Title: Ethyl pyruvate protects rats from phosgene-induced pulmonary edema by inhibiting cyclooxygenase2 and inducible nitric oxide synthase expression.
Journal: Journal of applied toxicology : JAT 20130101
Title: Effects of Ethyl Pyruvate on Allodynia, TNF-α Expression, and Apoptosis in the Dorsal Root Ganglion after Spinal Nerve Ligation Injury.
Journal: The Korean journal of pain 20121001
Title: Ethyl pyruvate induces heme oxygenase-1 through p38 mitogen-activated protein kinase activation by depletion of glutathione in RAW 264.7 cells and improves survival in septic animals.
Journal: Antioxidants & redox signaling 20120915
Title: HMGB1 in renal ischemic injury.
Journal: American journal of physiology. Renal physiology 20120915
Title: A comparison of the effects of N-acetylcysteine and ethyl pyruvate on experimental testicular ischemia-reperfusion injury.
Journal: Fertility and sterility 20120901
Title: Ethyl pyruvate ameliorates endotoxin-induced corneal inflammation.
Journal: Investigative ophthalmology & visual science 20120901
Title: Protective effect of ethyl pyruvate on liver injury in streptozotocin-induced diabetic rats.
Journal: Acta gastro-enterologica Belgica 20120901
Title: Role of high mobility group box 1 (HMGB1) in wound healing.
Journal: The Journal of surgical research 20120701
Title: Ethyl pyruvate-mediated Nrf2 activation and hemeoxygenase 1 induction in astrocytes confer protective effects via autocrine and paracrine mechanisms.
Journal: Neurochemistry international 20120701
Title: HMGB1 was a pivotal synergistic effecor for CpG oligonucleotide to enhance the progression of human lung cancer cells.
Journal: Cancer biology & therapy 20120701
Title: Therapeutic treatment with ethyl pyruvate attenuates the severity of liver injury in rats with severe acute pancreatitis.
Journal: Pancreas 20120701
Title: Decontamination of green onions and baby spinach by vaporized ethyl pyruvate.
Journal: Journal of food protection 20120601
Title: Ethyl pyruvate reduces ventilation-induced neutrophil infiltration and oxidative stress.
Journal: Experimental biology and medicine (Maywood, N.J.) 20120601
Title: Ethyl pyruvate promotes spinal cord repair by ameliorating the glial microenvironment.
Journal: British journal of pharmacology 20120501
Title: Inhibitory effects of ethyl pyruvate administration on human gastric cancer growth via regulation of the HMGB1-RAGE and Akt pathways in vitro and in vivo.
Journal: Oncology reports 20120501
Title: HMGB1: a potential therapeutic target for myocardial ischemia and reperfusion injury.
Journal: International journal of cardiology 20120322
Title: Ethyl pyruvate ameliorates albuminuria and glomerular injury in the animal model of diabetic nephropathy.
Journal: American journal of physiology. Renal physiology 20120301
Title: Differences in lipopolysaccharide- and lipoteichoic acid-induced cytokine/chemokine expression.
Journal: Intensive care medicine 20120201
Title: Peculiarity of methoxy group-substituted phenylhydrazones in Fischer indole synthesis.
Journal: Proceedings of the Japan Academy. Series B, Physical and biological sciences 20120111
Title: Chiral ammonium-capped rhodium(0) nanocatalysts: synthesis, characterization, and advances in asymmetric hydrogenation in neat water.
Journal: ChemSusChem 20120109
Title: Ethyl pyruvate reduces myocardial ischemia and reperfusion injury by inhibiting high mobility group box 1 protein in rats.
Journal: Molecular biology reports 20120101
Title: An in vitro spinal cord slice preparation for recording from lumbar motoneurons of the adult mouse.
Journal: Journal of neurophysiology 20120101
Title: Effects of continuous erythropoietin receptor activator in sepsis-induced acute kidney injury and multi-organ dysfunction.
Journal: PloS one 20120101
Title: Ethyl pyruvate reduces liver injury at early phase but impairs regeneration at late phase in acetaminophen overdose.
Journal: Critical care (London, England) 20120101
Title: Ethyl pyruvate for the treatment of acetaminophen intoxication: alternative to N-acetylcysteine?
Journal: Critical care (London, England) 20120101
Title: Reperfusion strategies in the management of extremity vascular injury with ischaemia.
Journal: The British journal of surgery 20120101
Title: Accelerated rejection of the second transplants of immunogenic tumor in mice under inhibition of indoleamine 2,3-dioxygenase activity by ethyl pyruvate.
Journal: Experimental oncology 20120101
Title: Toll-like receptors in ischaemia and its potential role in the pathophysiology of muscle damage in critical limb ischaemia.
Journal: Cardiology research and practice 20120101
Title: Small interference RNA targeting TLR4 gene effectively attenuates pulmonary inflammation in a rat model.
Journal: Journal of biomedicine & biotechnology 20120101
Title: Reactive oxygen species and inhibitors of inflammatory enzymes, NADPH oxidase, and iNOS in experimental models of Parkinson's disease.
Journal: Mediators of inflammation 20120101
Title: Nicotinic acetylcholine receptor agonists attenuate septic acute kidney injury in mice by suppressing inflammation and proteasome activity.
Journal: PloS one 20120101
Title: Therapeutic effect of captopril, pentoxifylline, and cordyceps sinensis in pre-hepatic portal hypertensive rats.
Journal: Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association 20120101
Title: Ethyl pyruvate attenuates formalin-induced inflammatory nociception by inhibiting neuronal ERK phosphorylation.
Journal: Molecular pain 20120101
Title: Glutathione supplementation attenuates lipopolysaccharide-induced mitochondrial dysfunction and apoptosis in a mouse model of acute lung injury.
Journal: Frontiers in physiology 20120101
Title: Immunological and nonimmunological effects of indoleamine 2,3-dioxygenase on breast tumor growth and spontaneous metastasis formation.
Journal: Clinical & developmental immunology 20120101
Title: Dengue virus infection mediates HMGB1 release from monocytes involving PCAF acetylase complex and induces vascular leakage in endothelial cells.
Journal: PloS one 20120101
Title: Uric acid and HMGB1 are involved in the induction of autoantibodies elicited in mice infected with mouse hepatitis virus A59.
Journal: Autoimmunity 20111201
Title: [Ethyl pyruvate inhibited HMGB1 expression induced by LPS in macrophages].
Journal: Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology 20111201
Title: Inhaled nitric oxide aggravates phosgene model of acute lung injury.
Journal: Inhalation toxicology 20111101
Title: Ethyl 2-[(carbamothioyl-amino)-imino]-propano-ate.
Journal: Acta crystallographica. Section E, Structure reports online 20110801
Title: Metabolic agents that enhance ATP can improve cognitive functioning: a review of the evidence for glucose, oxygen, pyruvate, creatine, and L-carnitine.
Journal: Nutrients 20110801
Title: Ethyl pyruvate rescues nigrostriatal dopaminergic neurons by regulating glial activation in a mouse model of Parkinson's disease.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20110715
Title: Preventive effects of ethyl pyruvate on endotoxin-induced uveitis in rats.
Journal: Investigative ophthalmology & visual science 20110701
Title: Macrophage activation by factors released from acetaminophen-injured hepatocytes: potential role of HMGB1.
Journal: Toxicology and applied pharmacology 20110615
Title: In vivo anticoagulant effect of ethyl pyruvate in endotoxemic rats.
Journal: Thrombosis research 20110601
Title: Kainic Acid-induced neurotoxicity: targeting glial responses and glia-derived cytokines.
Journal: Current neuropharmacology 20110601
Title: Ethyl pyruvate reduces acute lung injury via regulation of iNOS and HO-1 expression in endotoxemic rats.
Journal: The Journal of surgical research 20110515
Title: Ethyl pyruvate decreases proinflammatory gene expression in lipopolysaccharide-stimulated equine monocytes.
Journal: Veterinary immunology and immunopathology 20110515
Title: Preliminary safety and biological efficacy studies of ethyl pyruvate in normal mature horses.
Journal: Equine veterinary journal 20110501
Title: Alternative fluids for prehospital resuscitation: 'pharmacological' resuscitation fluids.
Journal: The Journal of trauma 20110501
Title: Ethyl pyruvate, an anti-inflammatory agent, inhibits tumor angiogenesis through inhibition of the NF-κB signaling pathway.
Journal: Cancer letters 20110428
Title: Inhibitory mechanism of MMP-9 gene expression by ethyl pyruvate in lipopolysaccharide-stimulated BV2 microglial cells.
Journal: Neuroscience letters 20110408
Title: Pyruvate: immunonutritional effects on neutrophil intracellular amino or alpha-keto acid profiles and reactive oxygen species production.
Journal: Amino acids 20110401
Title: High-mobility group box 1, oxidative stress, and disease.
Journal: Antioxidants & redox signaling 20110401
Title: The first case of competitive heterogeneously catalyzed enantioselective hydrogenation of ketones.
Journal: Chemical communications (Cambridge, England) 20110207
Title: Interaction of ethyl pyruvate in vitro with NF-κB subunits, RelA and p50.
Journal: European journal of pharmacology 20110110
Title: Effects of ethyl pyruvate and other α-keto carboxylic acid derivatives in a rat model of multivisceral ischemia and reperfusion.
Journal: The Journal of surgical research 20110101
Title: Ethyl pyruvate preserves IGF-I sensitivity toward mTOR substrates and protein synthesis in C2C12 myotubes.
Journal: Endocrinology 20110101
Title: Postischemic treatment with ethyl pyruvate prevents adenosine triphosphate depletion, ameliorates inflammation, and decreases thrombosis in a murine model of hind-limb ischemia and reperfusion.
Journal: The Journal of trauma 20110101
Title: A hepatic protein, fetuin-A, occupies a protective role in lethal systemic inflammation.
Journal: PloS one 20110101
Title: Higher hypochlorous acid scavenging activity of ethyl pyruvate compared to its sodium salt.
Journal: Bioscience, biotechnology, and biochemistry 20110101
Title: The role of receptor for advanced glycation endproducts (RAGE) in infection.
Journal: Critical care (London, England) 20110101
Title: Systemically administered ligands of Toll-like receptor 2, -4, and -9 induce distinct inflammatory responses in the murine lung.
Journal: Mediators of inflammation 20110101
Title: Trauma is danger.
Journal: Journal of translational medicine 20110101
Title: An observational cohort study of the kynurenine to tryptophan ratio in sepsis: association with impaired immune and microvascular function.
Journal: PloS one 20110101
Title: Beneficial effects of ethyl pyruvate through inhibiting high-mobility group box 1 expression and TLR4/NF-κB pathway after traumatic brain injury in the rat.
Journal: Mediators of inflammation 20110101
Title: Prevention of cataract in diabetic mice by topical pyruvate.
Journal: Clinical ophthalmology (Auckland, N.Z.) 20110101
Title: Tissue factor, blood coagulation, and beyond: an overview.
Journal: International journal of inflammation 20110101
Title: Metabolomics of oxidative stress in recent studies of endogenous and exogenously administered intermediate metabolites.
Journal: International journal of molecular sciences 20110101
Title: Differential regional expression patterns of α-synuclein, TNF-α, and IL-1β; and variable status of dopaminergic neurotoxicity in mouse brain after Paraquat treatment.
Journal: Journal of neuroinflammation 20110101
Title: The beneficial effect of direct peritoneal resuscitation on septic shock in rats.
Journal: Journal of biomedicine & biotechnology 20110101
Title: Using Complementary and Alternative Medicines to Target the Host Response during Severe Influenza.
Journal: Evidence-based complementary and alternative medicine : eCAM 20101201
Title: HMGB1 activates nuclear factor-κB signaling by RAGE and increases the production of TNF-α in human umbilical vein endothelial cells.
Journal: Immunobiology 20101201
Title: Transglutaminase 2 expression induced by lipopolysaccharide stimulation together with NO synthase induction in cultured astrocytes.
Journal: Neurochemistry international 20101201
Title: [Effect of ethyl pyruvate on expression of inflammatory factors and mitogen-activated protein kinase proteins in renal ischemic/reperfusion injury in BABL/c mice].
Journal: Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue 20101201
Title: Ethyl pyruvate has anti-inflammatory and delayed myocardial protective effects after regional ischemia/reperfusion injury.
Journal: Yonsei medical journal 20101101
Title: Ethyl pyruvate diminishes the endotoxin-induced inflammatory response of bovine mammary endothelial cells.
Journal: Journal of dairy science 20101101
Title: Ethyl pyruvate downregulates tumor necrosis factor alpha and interleukin (IL)-6 and upregulates IL-10 in lipopolysaccharide-stimulated canine peripheral blood mononuclear cells.
Journal: The Journal of veterinary medical science 20101001
Title: Beneficial effects of sodium or ethyl pyruvate after traumatic brain injury in the rat.
Journal: Experimental neurology 20101001
Title: Cell to Cell Interaction Can Activate Membrane-bound APRIL Which Are Expressed on Inflammatory Macrophages.
Journal: Immune network 20101001
Title: Ethyl pyruvate stabilizes hypoxia-inducible factor 1 alpha via stimulation of the TCA cycle.
Journal: Cancer letters 20100928
Title: HMGB1 release and redox regulates autophagy and apoptosis in cancer cells.
Journal: Oncogene 20100923
Title: Ethyl pyruvate prevents inflammatory responses and organ damage during resuscitation in porcine hemorrhage.
Journal: Shock (Augusta, Ga.) 20100801
Title: Inhibition by ethyl pyruvate of the nuclear translocation of nuclear factor-kappaB in cultured lung epithelial cells.
Journal: Pulmonary pharmacology & therapeutics 20100801
Title: The biochemical basis for the anti-inflammatory and cytoprotective actions of ethyl pyruvate and related compounds.
Journal: Biochemical pharmacology 20100715
Title: Association between high-mobility group box-1 protein release and immune function of dendritic cells in thermal injury.
Journal: Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 20100701
Title: Responses of cultured human keratocytes and myofibroblasts to ethyl pyruvate: a microarray analysis of gene expression.
Journal: Investigative ophthalmology & visual science 20100601
Title: Ethyl pyruvate prevents intestinal inflammatory response and oxidative stress in a rat model of extrahepatic cholestasis.
Journal: The Journal of surgical research 20100515
Title: Diastereoselective synthesis of fused [1,3]oxazines from ethyl pyruvate, activated acetylenes and N-heterocycles.
Journal: Molecular diversity 20100501
Title: Hypertonic sodium pyruvate solution is more effective than Ringer's ethyl pyruvate in the treatment of hemorrhagic shock.
Journal: Shock (Augusta, Ga.) 20100501
Title: Intraocular penetration of pyruvate following its topical administration in mice.
Journal: Molecular and cellular biochemistry 20100501
Title: Cancer and inflammation: promise for biologic therapy.
Journal: Journal of immunotherapy (Hagerstown, Md. : 1997) 20100501
Title: Metabolic imaging in the anesthetized rat brain using hyperpolarized [1-13C] pyruvate and [1-13C] ethyl pyruvate.
Journal: Magnetic resonance in medicine 20100501
Title: Ethyl pyruvate has a neuroprotective effect through activation of extracellular signal-regulated kinase in Parkinson's disease model.
Journal: Biochemical and biophysical research communications 20100409
Title: [Influence of splenic high mobility group box-1 protein on immune function of regulatory T lymphocytes in scald rats].
Journal: Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns 20100401
Title: Ethyl (2E)-2-(hydroxy-imino)propanoate.
Journal: Acta crystallographica. Section E, Structure reports online 20100401
Title: Role of high-mobility group box 1 protein in the pathogenesis of intestinal barrier injury in rats with severe acute pancreatitis.
Journal: Pancreas 20100301
Title: Ethyl pyruvate protects against hypoxic-ischemic brain injury via anti-cell death and anti-inflammatory mechanisms.
Journal: Neurobiology of disease 20100301
Title: Immunotherapeutic suppression of indoleamine 2,3-dioxygenase and tumor growth with ethyl pyruvate.
Journal: Cancer research 20100301
Title: Highly diastereoselective synthesis of modified nucleosides via an asymmetric multicomponent reaction.
Journal: Chemical communications (Cambridge, England) 20100227
Title: Ethyl pyruvate inhibits peroxynitrite-induced DNA damage and hydroxyl radical generation: implications for neuroprotection.
Journal: Neurochemical research 20100201
Title: Natural alkaloids and synthetic relatives as chiral templates of the Orito's reaction.
Journal: Chirality 20100101
Title: Combination treatment with ethyl pyruvate and aspirin enhances neuroprotection in the postischemic brain.
Journal: Neurotoxicity research 20100101
Title: LucidDraw: efficiently visualizing complex biochemical networks within MATLAB.
Journal: BMC bioinformatics 20100101
Title: Peritoneal inflammation after twenty-week exposure to dialysis solution: effect of solution versus catheter-foreign body reaction.
Journal: Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis 20100101
Title: Proline-Glycine-Proline (PGP) and High Mobility Group Box Protein-1 (HMGB1): Potential Mediators of Cystic Fibrosis Airway Inflammation.
Journal: The open respiratory medicine journal 20100101
Title: Novel insights for systemic inflammation in sepsis and hemorrhage.
Journal: Mediators of inflammation 20100101
Title: DAMPening inflammation by modulating TLR signalling.
Journal: Mediators of inflammation 20100101
Title: Ethyl pyruvate therapy attenuates experimental severe arthritis caused by type II collagen (CII) in the mouse (CIA).
Journal: International journal of immunopathology and pharmacology 20100101
Title: Current and emerging strategies for the treatment and management of systemic lupus erythematosus based on molecular signatures of acute and chronic inflammation.
Journal: Journal of inflammation research 20100101
Title: Quercetin prevents LPS-induced high-mobility group box 1 release and proinflammatory function.
Journal: American journal of respiratory cell and molecular biology 20091201
Title: Ethyl pyruvate enhances intra-resuscitation hemodynamics in prolonged ventricular fibrillation arrest.
Journal: Resuscitation 20091201
Title: Autophagy inhibition in combination cancer treatment.
Journal: Current opinion in investigational drugs (London, England : 2000) 20091201
Title: Diastereoselective synthesis of fused [1,3]thiazolo[1,3]oxazins and [1,3]oxazino[2,3-b][1,3]benzothiazoles.
Journal: Molecular diversity 20091101
Title: Modulation of intracellular ROS levels by TIGAR controls autophagy.
Journal: The EMBO journal 20091007
Title: Shape-selective enantioselective hydrogenation on Pt nanoparticles.
Journal: Journal of the American Chemical Society 20090902
Title: Ethyl pyruvate decreases HMGB1 release and ameliorates murine colitis.
Journal: Journal of leukocyte biology 20090901
Title: Ethyl pyruvate administration inhibits hepatic tumor growth.
Journal: Journal of leukocyte biology 20090901
Title: Nuclear factor kappaB inhibitors alleviate and the proteasome inhibitor PS-341 exacerbates radiation toxicity in zebrafish embryos.
Journal: Molecular cancer therapeutics 20090901
Title: Beneficial effects of ethyl pyruvate in a mouse model of spinal cord injury.
Journal: Shock (Augusta, Ga.) 20090801
Title: Treatment with green tea extract attenuates secondary inflammatory response in an experimental model of spinal cord trauma.
Journal: Naunyn-Schmiedeberg's archives of pharmacology 20090801
Title: Can we predict the effects of NF-kappaB inhibition in sepsis? Studies with parthenolide and ethyl pyruvate.
Journal: Expert opinion on investigational drugs 20090801
Title: [Effects of ethyl pyruvate on injuries of sepsis in mice].
Journal: Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue 20090801
Title: Ethyl pyruvate modulates adhesive and secretory reactions in human lung epithelial cells.
Journal: Life sciences 20090605
Title: A phase II multicenter double-blind placebo-controlled study of ethyl pyruvate in high-risk patients undergoing cardiac surgery with cardiopulmonary bypass.
Journal: Journal of cardiothoracic and vascular anesthesia 20090601
Title: Ethyl pyruvate attenuates spinal cord ischemic injury with a wide therapeutic window through inhibiting high-mobility group box 1 release in rabbits.
Journal: Anesthesiology 20090601
Title: Anti-inflammatory resuscitation improves survival in hemorrhage with trauma.
Journal: The Journal of trauma 20090601
Title: The Stimulation of CD147 Induces MMP-9 Expression through ERK and NF-kappaB in Macrophages: Implication for Atherosclerosis.
Journal: Immune network 20090601
Title: Ethyl pyruvate ameliorates liver injury secondary to severe acute pancreatitis.
Journal: The Journal of surgical research 20090515
Title: Effect of ethyl pyruvate on physical and immunological barriers of the small intestine in a rat model of sepsis.
Journal: The Journal of trauma 20090501
Title: Neuroprotective effects of ethyl pyruvate on brain energy metabolism after ischemia-reperfusion injury: a 31P-nuclear magnetic resonance study.
Journal: Neurochemical research 20090401
Title: Ethyl pyruvate improves survival in awake hemorrhage.
Journal: Journal of molecular medicine (Berlin, Germany) 20090401
Title: The effect of high-mobility group box 1 protein on activity of regulatory T cells after thermal injury in rats.
Journal: Shock (Augusta, Ga.) 20090301
Title: Ethyl pyruvate protects colonic anastomosis from ischemia-reperfusion injury.
Journal: Surgical innovation 20090301
Title: Anti-inflammatory adjuvant in resuscitation fluids improves survival in hemorrhage.
Journal: Critical care medicine 20090301
Title: Would you like your colloid straight or with a twist of an anti-inflammatory antioxidant?
Journal: Critical care medicine 20090301
Title: Antioxidant effect of ethyl pyruvate in respiring neonatal cerebrocortical slices after H(2)O(2) stress.
Journal: Neurochemistry international 20090201
Title: Ethyl pyruvate reduces the development of zymosan-induced generalized inflammation in mice.
Journal: Critical care medicine 20090101
Title: Heme Oxygenase-1 is an Essential Cytoprotective Component in Oxidative Tissue Injury Induced by Hemorrhagic Shock.
Journal: Journal of clinical biochemistry and nutrition 20090101
Title: Ethyl pyruvate reduces mortality in an endotoxin-induced severe acute lung injury mouse model.
Journal: Respiratory research 20090101
Title: The Impact of Adenosine Fast Induction of Myocardial Arrest during CABG on Myocardial Expression of Apoptosis-Regulating Genes Bax and Bcl-2.
Journal: Cardiology research and practice 20090101
Title: Methyl-2-acetamidoacrylate, an ethyl pyruvate analog, decreases sepsis-induced acute kidney injury in mice.
Journal: American journal of physiology. Renal physiology 20081201
Title: Stereoselective reduction of carbonyl compounds with Actinomycete: purification and characterization of three alpha-keto ester reductases from Streptomyces avermitilis.
Journal: Bioscience, biotechnology, and biochemistry 20081201
Title: 1-(1-Naphthyl)ethylamine adsorption on platinum surfaces: on the mechanism of chiral modification in catalysis.
Journal: Journal of the American Chemical Society 20081105
Title: The effect of ethyl pyruvate on dapsone-induced methemoglobinemia in rats.
Journal: Clinical toxicology (Philadelphia, Pa.) 20081101
Title: Relationship between high-mobility group box 1 protein release and T-cell suppression in rats after thermal injury.
Journal: Shock (Augusta, Ga.) 20081001
Title: The role of high mobility group box1 in pulmonary fibrosis.
Journal: American journal of respiratory cell and molecular biology 20081001
Title: Ethyl pyruvate has an anti-inflammatory effect by inhibiting ROS-dependent STAT signaling in activated microglia.
Journal: Free radical biology & medicine 20081001
Title: Polar [3 + 2] cycloaddition of ketones with electrophilically activated carbonyl ylides. Synthesis of spirocyclic dioxolane indolinones.
Journal: Organic & biomolecular chemistry 20080907
Title: Ethyl pyruvate and ethyl lactate down-regulate the production of pro-inflammatory cytokines and modulate expression of immune receptors.
Journal: Biochemical pharmacology 20080901
Title: The role of high-mobility group box-1 in renal ischemia and reperfusion injury and the effect of ethyl pyruvate.
Journal: Transplantation proceedings 20080901
Title: Delayed ethyl pyruvate therapy attenuates experimental severe acute pancreatitis via reduced serum high mobility group box 1 levels in rats.
Journal: World journal of gastroenterology 20080728
Title: Systemic release of high mobility group box 1 protein during severe murine influenza.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20080715
Title: Ethyl pyruvate modulates acute inflammatory reactions in human endothelial cells in relation to the NF-kappaB pathway.
Journal: British journal of pharmacology 20080701
Title: Synphos modified Pt nanoclusters, their heterogenization by silica sol-gel entrapment, and catalytic activity in hydrogenolysis of bicyclo[2.2.2]oct-7-enes and hydrogenation of ethyl pyruvate.
Journal: Nanotechnology 20080604
Title: Effects of ethyl pyruvate on myocardial apoptosis and expression of Bcl-2 and Bax proteins after ischemia-reperfusion in rats.
Journal: Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20080601
Title: Synthesis and biological activity of functionalized indole-2-carboxylates, triazino- and pyridazino-indoles.
Journal: Archiv der Pharmazie 20080501
Title: Ethyl pyruvate decreased early nuclear factor-kappaB levels but worsened survival in lipopolysaccharide-challenged mice.
Journal: Critical care medicine 20080401
Title: Bull's eye missed by the magic bullet: preclinical investigations, publication bias, and promising new interventions.
Journal: Critical care medicine 20080401
Title: Ethyl pyruvate reduces germ cell-specific apoptosis and oxidative stress in rat model of testicular torsion/detorsion.
Journal: Journal of pediatric surgery 20080401
Title: Targeting the lipopolysaccharides: still a matter of debate?
Journal: Current opinion in anaesthesiology 20080401
Title: Ethyl pyruvate.
Journal: Current opinion in anaesthesiology 20080401
Title: Ethyl pyruvate inhibits hypoxic pulmonary vasoconstriction and attenuates pulmonary artery cytokine expression.
Journal: The Journal of surgical research 20080301
Title: [Protective effect of ethyl pyruvate on barrier function of intestinal mucosa in dogs with septic shock].
Journal: Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery 20080301
Title: Sepsis: from bench to bedside.
Journal: Clinics (Sao Paulo, Brazil) 20080201
Title: The effect of ethyl pyruvate on oxidative stress in intestine and bacterial translocation after thermal injury.
Journal: The Journal of surgical research 20080101
Title: [Effect of ethyl pyruvate on indices of tissue oxygenation and perfusion in dogs with septic shock].
Journal: Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue 20080101
Title: Protective effects of ethyl pyruvate treatment on paraquat-intoxicated rats.
Journal: Human & experimental toxicology 20080101
Title: Introduction of an agent-based multi-scale modular architecture for dynamic knowledge representation of acute inflammation.
Journal: Theoretical biology & medical modelling 20080101
Title: Bench-to-bedside review: latest results in hemorrhagic shock.
Journal: Critical care (London, England) 20080101
Title: Preconditioning of carbon monoxide releasing molecule-derived CO attenuates LPS-induced activation of HUVEC.
Journal: International journal of biological sciences 20080101
Title: Curcumin inhibits glyoxalase 1: a possible link to its anti-inflammatory and anti-tumor activity.
Journal: PloS one 20080101
Title: Management of sepsis.
Journal: BMJ (Clinical research ed.) 20071103
Title: Intrapulmonary delivery of ethyl pyruvate attenuates lipopolysaccharide- and lipoteichoic acid-induced lung inflammation in vivo.
Journal: Shock (Augusta, Ga.) 20071101
Title: Ethyl pyruvate, a potentially effective mitigator of damage after total-body irradiation.
Journal: Radiation research 20071101
Title: Exogenous ethyl pyruvate versus pyruvate during metabolic recovery after oxidative stress in neonatal rat cerebrocortical slices.
Journal: Anesthesiology 20071001
Title: Ethyl pyruvate improves survival and ameliorates distant organ injury in rats with severe acute pancreatitis.
Journal: Pancreas 20071001
Title: The protective effect of ethyl pyruvate on lung injury after burn in rats.
Journal: Saudi medical journal 20071001
Title: [Effect of ethyl pyruvate on renal high mobility group box-1 protein expression and acute kidney injury in rats with delayed resuscitation after thermal injury].
Journal: Zhonghua wai ke za zhi [Chinese journal of surgery] 20070901
Title: Oxidative damage in rat erythrocyte membranes following ethanol intake: effect of ethyl pyruvate.
Journal: Chemico-biological interactions 20070830
Title: Role of guiding groups in cinchona-modified platinum for controlling the sense of enantiodifferentiation in the hydrogenation of ketones.
Journal: Journal of the American Chemical Society 20070829
Title: Ethyl pyruvate induces necrosis-to-apoptosis switch and inhibits high mobility group box protein 1 release in A549 lung adenocarcinoma cells.
Journal: International journal of molecular medicine 20070801
Title: [Advances in high mobility group box-1 protein mediated multiple organ dysfunction and its potential interventional strategies].
Journal: Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae 20070801
Title: Ethyl pyruvate: a novel anti-inflammatory agent.
Journal: Journal of internal medicine 20070401
Title: Ethyl pyruvate: a novel treatment for sepsis.
Journal: Current drug targets 20070401
Title: Enantioselective hydrogenation of ethyl pyruvate over diop modified Pt nanoclusters. Determination of geometry of the ligand adsorption mode via DRIFTS.
Journal: Physical chemistry chemical physics : PCCP 20070221
Title: Beneficial effects of ethyl pyruvate in septic shock from peritonitis.
Journal: Archives of surgery (Chicago, Ill. : 1960) 20070201
Title: Promising therapeutic agents for sepsis.
Journal: Trends in microbiology 20070101
Title: Protective effect of ethyl pyruvate on msP rat leukocytes damaged by alcohol intake.
Journal: Journal of applied toxicology : JAT 20070101
Title: HMGB1 as a potential therapeutic target.
Journal: Novartis Foundation symposium 20070101
Title: Ethyl pyruvate: a novel treatment for sepsis.
Journal: Novartis Foundation symposium 20070101
Title: The first organocatalytic carbonyl-ene reaction: isomerisation-free C-C bond formations catalysed by H-bonding thio-ureas.
Journal: Beilstein journal of organic chemistry 20070101
Title: Bench-to-bedside review: High-mobility group box 1 and critical illness.
Journal: Critical care (London, England) 20070101
Title: A major ingredient of green tea rescues mice from lethal sepsis partly by inhibiting HMGB1.
Journal: PloS one 20070101
Title: Sulfur mustard toxicity following dermal exposure: role of oxidative stress, and antioxidant therapy.
Journal: Journal of burns and wounds 20070101
Title: Ethyl pyruvate exerts combined anti-inflammatory and anticoagulant effects on human monocytic cells.
Journal: Thrombosis and haemostasis 20061201
Title: Ethyl pyruvate attenuates kainic acid-induced neuronal cell death in the mouse hippocampus.
Journal: Journal of neuroscience research 20061115
Title: Haemodynamic and metabolic effects of resuscitation with Ringer's ethyl pyruvate in the acute phase of porcine endotoxaemic shock.
Journal: Acta anaesthesiologica Scandinavica 20061101
Title: [Relation between level of expression of high mobility group protein B1 in hepatic tissue with the severity and prognosis of sepsis in rat].
Journal: Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue 20061101
Title: Is pyruvate an endogenous anti-inflammatory molecule?
Journal: Nutrition (Burbank, Los Angeles County, Calif.) 20060901
Title: Introduction to serial reviews on redox signaling in immune function and cellular responses in lung injury and diseases.
Journal: Free radical biology & medicine 20060701
Title: Pyruvate is an endogenous anti-inflammatory and anti-oxidant molecule.
Journal: Medical science monitor : international medical journal of experimental and clinical research 20060501
Title: Determination of geometric orientation of adsorbed cinchonidine on Pt and Fe and quiphos on Pt nanoclusters via DRIFTS.
Journal: Physical chemistry chemical physics : PCCP 20060321
Title: [Effect of treatment with ethyl pyruvate on multiple organ dysfunction and mortality following delayed resuscitation after burn injury in rat].
Journal: Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue 20060301
Title: [Effect of ethyl pyruvate on peroxidation injury of intestinal mucosa in rats with severe abdominal infection].
Journal: Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue 20060301
Title: Treatment of severe sepsis: where next? Current and future treatment approaches after the introduction of drotrecogin alfa.
Journal: Vascular health and risk management 20060301
Title: Highly enantioselective direct reductive coupling of conjugated alkynes and alpha-ketoesters via rhodium-catalyzed asymmetric hydrogenation.
Journal: Journal of the American Chemical Society 20060125
Title: Oxidative damage to lens in culture: reversibility by pyruvate and ethyl pyruvate.
Journal: Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde 20060101
Title: Bench-to-bedside review: critical illness-associated cognitive dysfunction--mechanisms, markers, and emerging therapeutics.
Journal: Critical care (London, England) 20060101
Title: The ethyl pyruvate analogues, diethyl oxaloproprionate, 2-acetamidoacrylate, and methyl-2-acetamidoacrylate, exhibit anti-inflammatory properties in vivo and/or in vitro.
Journal: Biochemical pharmacology 20051125
Title: Anti-inflammatory mechanism is involved in ethyl pyruvate-mediated efficacious neuroprotection in the postischemic brain.
Journal: Brain research 20051026
Title: Efficiency in isotetronic acid synthesis via a diamine-acid couple catalyzed ethyl pyruvate homoaldol reaction.
Journal: Organic letters 20051013
Title: Inhibition of the cerebral ischemic injury by ethyl pyruvate with a wide therapeutic window.
Journal: Stroke 20051001
Title: The cytokine activity of HMGB1--extracellular escape of the nuclear protein.
Journal: Chang Gung medical journal 20051001
Title: Ethyl pyruvate improves systemic and hepatosplanchnic hemodynamics and prevents lipid peroxidation in a porcine model of resuscitated hyperdynamic endotoxemia.
Journal: Critical care medicine 20050901
Title: Neonicotinoid nitroguanidine insecticide metabolites: synthesis and nicotinic receptor potency of guanidines, aminoguanidines, and their derivatives.
Journal: Chemical research in toxicology 20050901
Title: Ethyl pyruvate ameliorates ileus induced by bowel manipulation in mice.
Journal: Surgery 20050901
Title: [Effects of ethyl pyruvate on splenocyte proliferation and apoptosis in burn rats with delayed resuscitation].
Journal: Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue 20050701
Title: Dendrimer-enhanced MRI as a diagnostic and prognostic biomarker of sepsis-induced acute renal failure in aged mice.
Journal: Kidney international 20050601
Title: Oxoester oxidoreductase activities in new isolates of Pichia anomala from apple, grape and cane juices.
Journal: FEMS yeast research 20050401
Title: Future strategies in the treatment of acute renal failure: growth factors, stem cells, and other novel therapies.
Journal: Current opinion in pediatrics 20050401
Title: Ethyl pyruvate inhibits nuclear factor-kappaB-dependent signaling by directly targeting p65.
Journal: The Journal of pharmacology and experimental therapeutics 20050301
Title: Ringer's ethyl pyruvate in hemorrhagic shock and resuscitation does not improve early hemodynamics or tissue energetics.
Journal: Shock (Augusta, Ga.) 20050301
Title: Ethyl pyruvate enhances ATP levels, reduces oxidative stress and preserves cardiac function in a rat model of off-pump coronary bypass.
Journal: Heart, lung & circulation 20050301
Title: Ethyl pyruvate protects PC12 cells from dopamine-induced apoptosis.
Journal: European journal of pharmacology 20050131
Title: Ethyl pyruvate ameliorates liver ischemia-reperfusion injury by decreasing hepatic necrosis and apoptosis.
Journal: Transplantation 20050127
Title: [Effects of ethyl pyruvate on cell-mediated immune function in rats with delayed resuscitation after burn injury].
Journal: Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue 20050101
Title: Bench-to-bedside review: Amelioration of acute renal impairment using ethyl pyruvate.
Journal: Critical care (London, England) 20050101
Title: Ethyl pyruvate reduces liver injury in a murine model of extrahepatic cholestasis.
Journal: Shock (Augusta, Ga.) 20041001
Title: Synthesis of cladobotryal, CJ16,169, and CJ16,170.
Journal: Organic letters 20040819
Title: Native versus recombinant high-mobility group B1 proteins: functional activity in vitro.
Journal: Inflammation 20040801
Title: Ethyl pyruvate ameliorates distant organ injury in a murine model of acute necrotizing pancreatitis.
Journal: Critical care medicine 20040701
Title: Ethyl pyruvate: a simple solution?
Journal: Critical care medicine 20040701
Title: Ethyl pyruvate preserves cardiac function and attenuates oxidative injury after prolonged myocardial ischemia.
Journal: The Journal of thoracic and cardiovascular surgery 20040501
Title: Ethyl pyruvate: a novel treatment for sepsis and shock.
Journal: Minerva anestesiologica 20040501
Title: Direct catalytic asymmetric aldol reactions of pyruvates: scope and mechanism.
Journal: Organic & biomolecular chemistry 20040407
Title: Identification of catalyst surface species during asymmetric platinum-catalysed hydrogenation in a 'supercritical' solvent.
Journal: Chemical communications (Cambridge, England) 20040321
Title: Evidence that glutathione depletion is a mechanism responsible for the anti-inflammatory effects of ethyl pyruvate in cultured lipopolysaccharide-stimulated RAW 264.7 cells.
Journal: The Journal of pharmacology and experimental therapeutics 20040101
Title: 8th Annual Toronto Critical Care Medicine Symposium, 30 October-1 November 2003, Toronto, Ontario, Canada.
Journal: Critical care (London, England) 20040101
Title: Investigation of chiral reactions: the structural detection of new hydrogenated isocinchona alkaloids from mixtures without isolation using electrospray ionization tandem mass spectrometry.
Journal: Rapid communications in mass spectrometry : RCM 20040101
Title: Ethyl pyruvate provides durable protection against inflammation-induced intestinal epithelial barrier dysfunction.
Journal: Shock (Augusta, Ga.) 20031201
Title: Dose-dependent effects of ethyl pyruvate in mice subjected to mesenteric ischemia and reperfusion.
Journal: Intensive care medicine 20031101
Title: Ethyl pyruvate decreases sepsis-induced acute renal failure and multiple organ damage in aged mice.
Journal: Kidney international 20031101
Title: Ethyl pyruvate ameliorates acute alcohol-induced liver injury and inflammation in mice.
Journal: The Journal of laboratory and clinical medicine 20031101
Title: Catalytic enantioselective transamination of alpha-keto esters: an organic approach to enzymatic reactions.
Journal: Chemical communications (Cambridge, England) 20031021
Title: Ringer's ethyl pyruvate solution: a novel resuscitation fluid for the treatment of hemorrhagic shock and sepsis.
Journal: The Journal of trauma 20030501
Title: Ethyl pyruvate ameliorates intestinal epithelial barrier dysfunction in endotoxemic mice and immunostimulated caco-2 enterocytic monolayers.
Journal: The Journal of pharmacology and experimental therapeutics 20030101
Title: Ethyl pyruvate: a novel anti-inflammatory agent.
Journal: Critical care medicine 20030101
Title: Hydrogenation of cinchona alkaloids over supported Pt catalyst.
Journal: Chirality 20030101
Title: Investigations in chiral reactions: identification of new adducts in the reactions of ethyl pyruvate with acetic anhydride and pyridine.
Journal: Rapid communications in mass spectrometry : RCM 20030101
Title: Resuscitation with Ringer's ethyl pyruvate solution prolongs survival and modulates plasma cytokine and nitrite/nitrate concentrations in a rat model of lipopolysaccharide-induced shock.
Journal: Shock (Augusta, Ga.) 20021201
Title: Possible mechanism for involvement of cysteine in aroma production in wine.
Journal: Journal of agricultural and food chemistry 20021009
Title: Structural characterization of acetylpyridinium-ethyl pyruvate adducts by electrospray ionization mass spectrometry.
Journal: Journal of mass spectrometry : JMS 20021001
Title: Ethyl pyruvate modulates inflammatory gene expression in mice subjected to hemorrhagic shock.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20020701
Title: Resuscitation from hemorrhagic shock with Ringer's ethyl pyruvate solution improves survival and ameliorates intestinal mucosal hyperpermeability in rats.
Journal: Shock (Augusta, Ga.) 20020601
Title: Unexpected change of the sense of the enantioselective hydrogenation of ethyl pyruvate catalyzed by a Pt-alumina-cinchona alkaloid system.
Journal: Chemical communications (Cambridge, England) 20020521
Title: Reactive oxygen species as mediators of organ dysfunction caused by sepsis, acute respiratory distress syndrome, or hemorrhagic shock: potential benefits of resuscitation with Ringer's ethyl pyruvate solution.
Journal: Current opinion in clinical nutrition and metabolic care 20020301
Title: A highly atom efficient, solvent promoted addition of tetraallylic, tetraallenic, and tetrapropargylic stannanes to carbonyl compounds.
Journal: The Journal of organic chemistry 20011116
Title: Ringer's ethyl pyruvate solution ameliorates ischemia/reperfusion-induced intestinal mucosal injury in rats.
Journal: Critical care medicine 20010801
Title: Ringer's ethyl pyruvate solution: a novel resuscitation fluid.
Journal: Minerva anestesiologica 20010401
Title: Fink MP. Ethyl pyruvate: a novel anti-inflammatory agent. J Intern Med. 2007 Apr;261(4):349-62.
