Home Amines 61714-27-0
61714-27-0,MFCD00012559
Catalog No.:AA003SB1

61714-27-0 | N-(6-Aminohexyl)-5-chloro-1-naphthalenesulfonamide HCl

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10mg
≥98%
in stock  
$82.00   $57.00
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50mg
≥98%
in stock  
$122.00   $85.00
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100mg
≥98%
in stock  
$199.00   $139.00
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500mg
≥98.0%(HPLC)
in stock  
$547.00   $383.00
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1g
>98.0%(HPLC)(N)
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$740.00   $518.00
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  • Technical Information
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  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA003SB1
Chemical Name:
N-(6-Aminohexyl)-5-chloro-1-naphthalenesulfonamide HCl
CAS Number:
61714-27-0
Molecular Formula:
C16H22Cl2N2O2S
Molecular Weight:
377.3291
MDL Number:
MFCD00012559
SMILES:
NCCCCCCNS(=O)(=O)c1cccc2c1cccc2Cl.Cl
NSC Number:
683545
Properties
Properties
 
Form:
Solid  
MP:
220-222 °C  
Solubility:
methanol: 25 mg/mL, clear, colorless  
Storage:
-20 ℃;  

Computed Properties
 
Complexity:
424  
Covalently-Bonded Unit Count:
2  
Heavy Atom Count:
23  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
8  

Literature

Title: Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.

Journal: Nature chemical biology 20091001

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: H Hidaka, et al. N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide, a Calmodulin Antagonist, Inhibits Cell Proliferation. Proc Natl Acad Sci U S A. 1981 Jul;78(7):4354-7.

Title: M Asano. Divergent Pharmacological Effects of Three Calmodulin Antagonists, N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide (W-7), Chlorpromazine and Calmidazolium, on Isometric Tension Development and Myosin Light Chain Phosphorylation in Intact Bovine Tracheal Smooth Muscle. J Pharmacol Exp Ther. 1989 Nov;251(2):764-73.

Title: H Itoh, et al. Direct Interaction of Calmodulin Antagonists With Ca2+/calmodulin-dependent Cyclic Nucleotide Phosphodiesterase. J Biochem. 1984 Dec;96(6):1721-6.

Title: Shigeyuki Yokokura, et al. Calmodulin Antagonists Induce Cell Cycle Arrest and Apoptosis in Vitro and Inhibit Tumor Growth in Vivo in Human Multiple Myeloma. BMC Cancer. 2014 Nov 26;14:882.

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Tags:61714-27-0 Molecular Formula|61714-27-0 MDL|61714-27-0 SMILES|61714-27-0 N-(6-Aminohexyl)-5-chloro-1-naphthalenesulfonamide HCl