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626-51-7,MFCD00002727
Catalog No.:AA003JOK

626-51-7 | 3-Methylglutaric acid

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1g
98%
in stock  
$13.00   $9.00
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5g
98%
in stock  
$16.00   $11.00
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25g
98%
in stock  
$54.00   $38.00
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  • Technical Information
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  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA003JOK
Chemical Name:
3-Methylglutaric acid
CAS Number:
626-51-7
Molecular Formula:
C6H10O4
Molecular Weight:
146.1412
MDL Number:
MFCD00002727
SMILES:
CC(CC(=O)O)CC(=O)O
NSC Number:
14870
Properties
Properties
 
BP:
299°C at 760 mmHg  
Form:
Solid  
MP:
81-86 °C(lit.)  
Refractive Index:
1.4336 (estimate)  
Storage:
Keep in dry area;Room Temperature;  

Computed Properties
 
Complexity:
125  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
10  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
4  
XLogP3:
0.1  

Literature

Title: Anaerobic degradation of 4-methylbenzoate via a specific 4-methylbenzoyl-CoA pathway.

Journal: Environmental microbiology 20120501

Title: The 3-methylglutaconic acidurias: what's new?

Journal: Journal of inherited metabolic disease 20120101

Title: Mitochondrial optic neuropathies - disease mechanisms and therapeutic strategies.

Journal: Progress in retinal and eye research 20110301

Title: Neurochemical evidence that 3-methylglutaric acid inhibits synaptic Na+,K+-ATPase activity probably through oxidative damage in brain cortex of young rats.

Journal: International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20110201

Title: Carboxylated hyperbranched poly(glycidol)s for preparation of pH-sensitive liposomes.

Journal: Journal of controlled release : official journal of the Controlled Release Society 20110105

Title: Computational analysis of a novel mutation in ETFDH gene highlights its long-range effects on the FAD-binding motif.

Journal: BMC structural biology 20110101

Title: OPA3, mutated in 3-methylglutaconic aciduria type III, encodes two transcripts targeted primarily to mitochondria.

Journal: Molecular genetics and metabolism 20100601

Title: Striatum is more vulnerable to oxidative damage induced by the metabolites accumulating in 3-hydroxy-3-methylglutaryl-CoA lyase deficiency as compared to liver.

Journal: International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20090601

Title: Inherited mitochondrial optic neuropathies.

Journal: Journal of medical genetics 20090301

Title: Costeff optic atrophy syndrome: new clinical case and novel molecular findings.

Journal: Journal of inherited metabolic disease 20081201

Title: Induction of oxidative stress by the metabolites accumulating in 3-methylglutaconic aciduria in cerebral cortex of young rats.

Journal: Life sciences 20080312

Title: 3-methylglutaconic aciduria type 4 manifesting as Leigh syndrome in 2 siblings.

Journal: Journal of child neurology 20070201

Title: 3-Methylglutaric acid as a 13C solid-state NMR standard.

Journal: Solid state nuclear magnetic resonance 20061001

Title: NMR spectroscopic studies on the late onset form of 3-methylglutaconic aciduria type I and other defects in leucine metabolism.

Journal: NMR in biomedicine 20060401

Title: A new sensitive isotropic-anisotropic separation experiment-SPEED MAS.

Journal: Journal of magnetic resonance (San Diego, Calif. : 1997) 20040601

Title: Vitamin E analogues as inducers of apoptosis: structure-function relation.

Journal: British journal of cancer 20030616

Title: 3-methyglutaconic aciduria in a Chinese patient with glycogen storage disease Ib.

Journal: Journal of inherited metabolic disease 20030101

Title: 3-Methylglutaconic aciduria type III in a non-Iraqi-Jewish kindred: clinical and molecular findings.

Journal: Molecular genetics and metabolism 20020701

Title: Type III 3-methylglutaconic aciduria (optic atrophy plus syndrome, or Costeff optic atrophy syndrome): identification of the OPA3 gene and its founder mutation in Iraqi Jews.

Journal: American journal of human genetics 20011201

Title: 3-Hydroxy-3-methylglutaric aciduria in an Italian patient is caused by a new nonsense mutation in the HMGCL gene.

Journal: Molecular genetics and metabolism 20010701

Title: Mitochondrial DNA depletion associated with partial complex II and IV deficiencies and 3-methylglutaconic aciduria.

Journal: Journal of child neurology 20010201

Title: Barich DH, et al. 3-Methylglutaric acid as a 13C solid-state NMR standard. Solid State Nucl Magn Reson. 2006 Oct;30(3-4):125-9.

Title: Dylan E Jones, et al. 3-Methylglutaric acid in energy metabolism. Clin Chim Acta. 2020 Mar;502:233-239.

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