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626-69-7,MFCD00672378
Catalog No.:AA00EC4R

626-69-7 | H-Ser(so3h)-oh

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250mg
2 weeks  
$483.00   $338.00
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1g
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$870.00   $609.00
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5g
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$2,318.00   $1,623.00
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00EC4R
Chemical Name:
H-Ser(so3h)-oh
CAS Number:
626-69-7
Molecular Formula:
C3H7NO6S
Molecular Weight:
185.1558
MDL Number:
MFCD00672378
SMILES:
C(C(C(=O)O)N)OS(=O)(=O)O
Properties
Computed Properties
 
Complexity:
227  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Heavy Atom Count:
11  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
4  
XLogP3:
-4.4  

Literature

Title: Antinociceptive effect of rat D-serine racemase inhibitors, L-serine-O-sulfate, and L-erythro-3-hydroxyaspartate in an arthritic pain model.

Journal: TheScientificWorldJournal 20120101

Title: 3-Phosphono-L-alanine as pyrophosphate mimic for DNA synthesis using HIV-1 reverse transcriptase.

Journal: Organic & biomolecular chemistry 20110107

Title: Functional roles of high-affinity glutamate transporters in cochlear afferent synaptic transmission in the mouse.

Journal: Journal of neurophysiology 20100501

Title: Conformationally-restricted amino acid analogues bearing a distal sulfonic acid show selective inhibition of system x(c)(-) over the vesicular glutamate transporter.

Journal: Bioorganic & medicinal chemistry letters 20100415

Title: Inhibition of glutamate transporters couples to Kv4.2 dephosphorylation through activation of extrasynaptic NMDA receptors.

Journal: Neuroscience 20100113

Title: Discovery of the first selective inhibitor of excitatory amino acid transporter subtype 1.

Journal: Journal of medicinal chemistry 20090226

Title: Purification and characterization of human brain serine racemase expressed in moderately halophilic bacteria.

Journal: Protein and peptide letters 20090101

Title: Riluzole enhances the activity of glutamate transporters GLAST, GLT1 and EAAC1.

Journal: European journal of pharmacology 20080114

Title: Molecular modeling and docking studies of glutamate racemase in Vibrio vulnificus CMCP6.

Journal: In silico biology 20080101

Title: Comparison of [(3)H]-(2S,4R)-4-methylglutamate and [(3)H]D-aspartate as ligands for binding and autoradiographic analyses of glutamate transporters.

Journal: Neurochemistry international 20071201

Title: Structural insight into the pharmacophore pocket of human glutamate carboxypeptidase II.

Journal: Journal of medicinal chemistry 20070712

Title: Human glutamate carboxypeptidase II inhibition: structures of GCPII in complex with two potent inhibitors, quisqualate and 2-PMPA.

Journal: Acta crystallographica. Section D, Biological crystallography 20070401

Title: Impact of the gliotoxin L-serine-O-sulphate on cellular metabolism in cultured rat astrocytes.

Journal: Neurochemistry international 20060601

Title: Dual substrate and reaction specificity in mouse serine racemase: identification of high-affinity dicarboxylate substrate and inhibitors and analysis of the beta-eliminase activity.

Journal: Biochemistry 20051004

Title: Substrate-induced modulation of glutamate uptake in human platelets.

Journal: British journal of pharmacology 20050701

Title: Regulation of serine racemase activity by amino acids.

Journal: Brain research. Molecular brain research 20050218

Title: Gliotoxins disrupt alanine metabolism and glutathione production in C6 glioma cells: a 13C NMR spectroscopic study.

Journal: Neurochemistry international 20041201

Title: Binding and transport of [3H](2S,4R)- 4-methylglutamate, a new ligand for glutamate transporters, demonstrate labeling of EAAT1 in cultured murine astrocytes.

Journal: Journal of neuroscience research 20040315

Title: Differentiation of substrate and non-substrate inhibitors of transport system xc(-): an obligate exchanger of L-glutamate and L-cystine.

Journal: Neuropharmacology 20040201

Title: Theanine and glutamate transporter inhibitors enhance the antitumor efficacy of chemotherapeutic agents.

Journal: Biochimica et biophysica acta 20031205

Title: An NMR study of alterations in [1-13C]glucose metabolism in C6 glioma cells by gliotoxic amino acids.

Journal: Neurochemistry international 20030501

Title: The 'glial' glutamate transporter, EAAT2 (Glt-1) accounts for high affinity glutamate uptake into adult rodent nerve endings.

Journal: Journal of neurochemistry 20030201

Title: Effects of glutamate transporter inhibitors on the antitumor activity of doxorubicin.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20021201

Title: Allosteric regulation of mouse brain serine racemase.

Journal: Neurochemical research 20021201

Title: Molecular mechanisms of cystine transport.

Journal: Biochemical Society transactions 20011101

Title: Characterization of Na+-coupled glutamate/aspartate transport by a rat brain astrocyte line expressing GLAST and EAAC1.

Journal: The Journal of membrane biology 20010701

Title: [(3)H](2S,4R)-4-Methylglutamate: a novel ligand for the characterization of glutamate transporters.

Journal: Journal of neurochemistry 20010601

Title: A Na+-dependent electrogenic glutamate transporter current in voltage-clamped cells of corpora allata in the cricket Gryllus bimaculatus.

Journal: Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 20010501

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