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63038-10-8,MFCD16660665
Catalog No.:AA0036WK

63038-10-8 | Senkyunolide A

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Purity
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1mg
≥98%
in stock  
$52.00   $36.00
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5mg
≥98%
in stock  
$208.00   $145.00
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10mg
≥98%
in stock  
$392.00   $274.00
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25mg
≥98%
in stock  
$850.00   $595.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA0036WK
Chemical Name:
Senkyunolide A
CAS Number:
63038-10-8
Molecular Formula:
C12H16O2
Molecular Weight:
192.2542
MDL Number:
MFCD16660665
SMILES:
CCCC[C@@H]1OC(=O)C2=C1CCC=C2
Properties
Properties
 
Form:
Solid  
Storage:
2-8℃;  

Computed Properties
 
Complexity:
299  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Heavy Atom Count:
14  
Hydrogen Bond Acceptor Count:
2  
Rotatable Bond Count:
3  
XLogP3:
2.7  

Downstream Synthesis Route

[1]Oguro,Daichi;Watanabe,Hidenori[Bioscience,BiotechnologyandBiochemistry,2011,vol.75,#8,p.1502-1505]

Literature

Title: [Influence of different solutions on extracting of active components in Danggui Chishao drug pair].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20120401

Title: Preparative isolation and purification of senkyunolide-I, senkyunolide-H and ferulic acid from Rhizoma Chuanxiong using counter-current chromatography.

Journal: Journal of separation science 20111201

Title: Components of rhizome extract of Cnidium officinale Makino and their in vitro biological effects.

Journal: Molecules (Basel, Switzerland) 20111021

Title: [Release characteristics in vitro and pharmacokinetics of da chuanxiong fang multiunit drug delivery system in rats].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20110901

Title: Isolation and identification of anti-inflammatory constituents from Ligusticum chuanxiong and their underlying mechanisms of action on microglia.

Journal: Neuropharmacology 20110501

Title: [UPLC-MS analysis of constituents of dachuanxiong fang active parts absorbed into blood].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20110501

Title: Effect and mechanism of senkyunolide I as an anti-migraine compound from Ligusticum chuanxiong.

Journal: The Journal of pharmacy and pharmacology 20110201

Title: Asymmetric synthesis and sensory evaluation of sedanenolide.

Journal: Bioscience, biotechnology, and biochemistry 20110101

Title: Senkyunolides reduce hydrogen peroxide-induced oxidative damage in human liver HepG2 cells via induction of heme oxygenase-1.

Journal: Chemico-biological interactions 20100212

Title: [Pharmacological activities of Z-ligustilide and metabolites in rats].

Journal: Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20090901

Title: Simultaneous determination of phenolic acids and phthalide compounds by liquid chromatography for quality assessment of Rhizoma cnidii.

Journal: Journal of AOAC International 20090101

Title: [Study on biligustilides from Angelica sinensis].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20081001

Title: Flavor enhancement of chicken broth from boiled celery constituents.

Journal: Journal of agricultural and food chemistry 20080123

Title: Relaxation effects of ligustilide and senkyunolide A, two main constituents of Ligusticum chuanxiong, in rat isolated aorta.

Journal: Journal of ethnopharmacology 20070522

Title: [High performance liquid chromatography-mass spectrometry analysis of radix Angelica sciensis].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20061101

Title: Identification and comparative determination of senkyunolide A in traditional Chinese medicinal plants Ligusticum chuanxiong and Angelica sinensis by HPLC coupled with DAD and ESI-MS.

Journal: Chemical & pharmaceutical bulletin 20051101

Title: LC-DAD-APCI-MS-based screening and analysis of the absorption and metabolite components in plasma from a rabbit administered an oral solution of danggui.

Journal: Analytical and bioanalytical chemistry 20050901

Title: [Determination of lactone components in chuanxiong by reversed-phase high performance liquid chromatography].

Journal: Se pu = Chinese journal of chromatography 20050901

Title: [Preparation of senkyunolide I by reversed-phase high performance liquid chromatography].

Journal: Se pu = Chinese journal of chromatography 20040101

Title: Mosquitocidal, nematicidal, and antifungal compounds from Apium graveolens L. seeds.

Journal: Journal of agricultural and food chemistry 20010101

Title: Dalei Zhang, et al. Separation and Purification of Z Ligustilide and Senkyunolide A from Ligusticum chuanxiong Hort. with Supercritical Fluid Extraction and High‐Speed Counter‐Current Chromatography. Separation Science and Technology, 41: 3397-3408, 2006.

Title: Kan WL, et al. Study of the anti-proliferative effects and synergy of phthalides from Angelica sinensis on colon cancer cells. J Ethnopharmacol. 2008 Oct 30;120(1):36-43.

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SDS
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