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631-69-6,MFCD04039448
Catalog No.:AA003OGX

631-69-6 | b-Boswellic acid

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1mg
≥95%
in stock  
$63.00   $44.00
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5mg
≥95%
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10mg
≥95%
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$459.00   $321.00
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25mg
98% by HPLC
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$1,018.00   $713.00
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50mg
98% by HPLC
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$1,690.00   $1,183.00
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100mg
98% by HPLC
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$2,877.00   $2,014.00
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500mg
98% by HPLC
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$9,149.00   $6,405.00
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1000mg
98% by HPLC
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$14,602.00   $10,222.00
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  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA003OGX
Chemical Name:
b-Boswellic acid
CAS Number:
631-69-6
Molecular Formula:
C30H48O3
Molecular Weight:
456.7003
MDL Number:
MFCD04039448
SMILES:
C[C@@H]1CC[C@]2([C@@H]([C@H]1C)C1=CC[C@H]3[C@@]([C@@]1(CC2)C)(C)CCC1[C@]3(C)CC[C@H]([C@]1(C)C(=O)O)O)C
Properties
Properties
 
BP:
556.0±50.0°C at 760 mmHg  
Form:
Solid  
MP:
130-135°C  
Storage:
Keep in dry area;2-8℃;  

Computed Properties
 
Complexity:
878  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
11  
Heavy Atom Count:
33  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
1  
XLogP3:
8.3  

Literature

Title: The synergistic effect of beta-boswellic acid and Nurr1 overexpression on dopaminergic programming of antioxidant glutathione peroxidase-1-expressing murine embryonic stem cells.

Journal: Neuroscience 20121011

Title: Boswellic acids from frankincense inhibit lipopolysaccharide functionality through direct molecular interference.

Journal: Biochemical pharmacology 20120101

Title: [Chemopreventive effect of boswellic acid and curcumin on 7,12-dimethyl benzanthracene-induced hamster cheek pouch carcinogenesis].

Journal: Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology 20111101

Title: Isolation of hypoxia-inducible factor 1 (HIF-1) inhibitors from frankincense using a molecularly imprinted polymer.

Journal: Investigational new drugs 20111001

Title: The 'MESACA' study: methylsulfonylmethane and boswellic acids in the treatment of gonarthrosis.

Journal: Advances in therapy 20111001

Title: A cyano analogue of boswellic acid induces crosstalk between p53/PUMA/Bax and telomerase that stages the human papillomavirus type 18 positive HeLa cells to apoptotic death.

Journal: European journal of pharmacology 20110625

Title: Development and evaluation of vesicular system for curcumin delivery.

Journal: Archives of dermatological research 20110301

Title: Two new triterpenoids from the resin of Boswellia carterii.

Journal: Journal of Asian natural products research 20110301

Title: Complexation with phosphatidyl choline as a strategy for absorption enhancement of boswellic acid.

Journal: Drug delivery 20101101

Title: Identification of human cathepsin G as a functional target of boswellic acids from the anti-inflammatory remedy frankincense.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20090901

Title: LY294002 enhances boswellic acid-induced apoptosis in colon cancer cells.

Journal: Anticancer research 20090801

Title: Boswellic acid blocks signal transducers and activators of transcription 3 signaling, proliferation, and survival of multiple myeloma via the protein tyrosine phosphatase SHP-1.

Journal: Molecular cancer research : MCR 20090101

Title: Boswellic acid inhibits expression of acid sphingomyelinase in intestinal cells.

Journal: Lipids in health and disease 20090101

Title: Oleanolic acid and its derivatives: new inhibitor of protein tyrosine phosphatase 1B with cellular activities.

Journal: Bioorganic & medicinal chemistry 20080915

Title: A simple high-performance liquid chromatographic method for the estimation of boswellic acids from the market formulations containing Boswellia serrata extract.

Journal: Journal of chromatographic science 20080901

Title: Boswellic acids: A leukotriene inhibitor also effective through topical application in inflammatory disorders.

Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20080601

Title: The gastric ulcer protective effect of boswellic acids, a leukotriene inhibitor from Boswellia serrata, in rats.

Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20080601

Title: Identification and functional analysis of cyclooxygenase-1 as a molecular target of boswellic acids.

Journal: Biochemical pharmacology 20080115

Title: Boswellic acids and glucosamine show synergistic effect in preclinical anti-inflammatory study in rats.

Journal: Bioorganic & medicinal chemistry letters 20070701

Title: CEC and EKC of natural compounds.

Journal: Electrophoresis 20070601

Title: Natural products as a gold mine for arthritis treatment.

Journal: Current opinion in pharmacology 20070601

Title: Anti-inflammatory activities of the triterpene acids from the resin of Boswellia carteri.

Journal: Journal of ethnopharmacology 20060919

Title: Boswellic acids stimulate arachidonic acid release and 12-lipoxygenase activity in human platelets independent of Ca2+ and differentially interact with platelet-type 12-lipoxygenase.

Journal: Molecular pharmacology 20060901

Title: Separation and quantification of terpenoids of Boswellia serrata Roxb. extract by planar chromatography techniques (TLC and AMD).

Journal: Journal of separation science 20060901

Title: Induction of central signalling pathways and select functional effects in human platelets by beta-boswellic acid.

Journal: British journal of pharmacology 20051001

Title: Boswellia carterii extract inhibits TH1 cytokines and promotes TH2 cytokines in vitro.

Journal: Clinical and diagnostic laboratory immunology 20050501

Title: Effects of Boswellia serrata in mouse models of chemically induced colitis.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20050401

Title: Boswellic acid acetate induces apoptosis through caspase-mediated pathways in myeloid leukemia cells.

Journal: Molecular cancer therapeutics 20050301

Title: Bioactive constituents from Boswellia papyrifera.

Journal: Journal of natural products 20050201

Title: Coupling of boswellic acid-induced Ca2+ mobilisation and MAPK activation to lipid metabolism and peroxide formation in human leucocytes.

Journal: British journal of pharmacology 20040101

Title: Immunomodulatory activity of boswellic acids of Boswellia serrata Roxb.

Journal: Indian journal of experimental biology 20031201

Title: Boswellic acid acetate induces differentiation and apoptosis in highly metastatic melanoma and fibrosarcoma cells.

Journal: Cancer detection and prevention 20030101

Title: Boswellic acids trigger apoptosis via a pathway dependent on caspase-8 activation but independent on Fas/Fas ligand interaction in colon cancer HT-29 cells.

Journal: Carcinogenesis 20021201

Title: Keto- and acetyl-keto-boswellic acids inhibit proliferation and induce apoptosis in Hep G2 cells via a caspase-8 dependent pathway.

Journal: International journal of molecular medicine 20021001

Title: Cytostatic and apoptosis-inducing activity of boswellic acids toward malignant cell lines in vitro.

Journal: Anticancer research 20020101

Title: [Therapy of active Crohn disease with Boswellia serrata extract H 15].

Journal: Zeitschrift fur Gastroenterologie 20010101

Title: Acetyl-boswellic acids are novel catalytic inhibitors of human topoisomerases I and IIalpha.

Journal: Molecular pharmacology 20000701

Title: Safayhi H, et al. Boswellic acids: novel, specific, nonredox inhibitors of 5-lipoxygenase. J Pharmacol Exp Ther. 1992 Jun;261(3):1143-6.

Title: Shao Y, et al. Inhibitory activity of boswellic acids from Boswellia serrata against human leukemia HL-60 cellsin culture. Planta Med. 1998 May;64(4):328-31

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Tags:631-69-6 Molecular Formula|631-69-6 MDL|631-69-6 SMILES|631-69-6 b-Boswellic acid