Home Other Building Blocks 63631-36-7
63631-36-7,MFCD13183926
Catalog No.:AA00EP25

63631-36-7 | ASPERPHENAMATE

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Purity
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1mg
≥95%
in stock  
$436.00   $305.00
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5mg
≥95%
in stock  
$1,628.00   $1,139.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00EP25
Chemical Name:
ASPERPHENAMATE
CAS Number:
63631-36-7
Molecular Formula:
C32H30N2O4
Molecular Weight:
506.5916
MDL Number:
MFCD13183926
SMILES:
O=C([C@@H](NC(=O)c1ccccc1)Cc1ccccc1)OC[C@@H](NC(=O)c1ccccc1)Cc1ccccc1
Properties
Computed Properties
 
Complexity:
732  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
2  
Heavy Atom Count:
38  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
12  
XLogP3:
6.1  

Literature

Title: Synthesis and in vitro antitumor activity of asperphenamate derivatives as autophagy inducer.

Journal: Bioorganic & medicinal chemistry letters 20120315

Title: Diterpenes from Leucas aspera inhibiting prostaglandin-induced contractions.

Journal: Journal of natural products 20060701

Title: A new method for asperphenamate synthesis and its antimicrobial activity evaluation.

Journal: Natural product research 20060520

Title: Petrosifungins A and B, novel cyclodepsipeptides from a sponge-derived strain of Penicillium brevicompactum.

Journal: Journal of natural products 20040301

Title: Alice M.Clark, et al. Synthesis of asperphenamate, a novel fungal metabolite. Phytochemistry

Title: LeiYuan, et al. Total synthesis and anticancer activity studies of the stereoisomers of asperphenamate and patriscabratine. Chinese Chemical Letters Volume 21, Issue 2, February 2010, Pages 155-158.

Title: Yuan L, et al. Discovery of novel cathepsin inhibitors with potent anti-metastatic effects in breast cancer cells. Bioorg Chem. 2018 Dec;81:672-680.

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SDS
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