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64790-15-4,MFCD00076518
Catalog No.:AA00E8RJ

64790-15-4 | H-Ala-Gln-Asp-Phe-Val-Gln-Trp-Leu-Met-Asn-Thr-OH

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5mg
in stock  
$147.00   $103.00
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10mg
in stock  
$200.00   $140.00
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25mg
in stock  
$254.00   $178.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00E8RJ
Chemical Name:
H-Ala-Gln-Asp-Phe-Val-Gln-Trp-Leu-Met-Asn-Thr-OH
CAS Number:
64790-15-4
Molecular Formula:
C61H89N15O18S
Molecular Weight:
1352.5141
MDL Number:
MFCD00076518
SMILES:
CSCC[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)O)[C@H](O)C)CC(=O)N)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2c1cccc2)NC(=O)[C@@H](NC(=O)[C@H](C(C)C)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](N)C)CCC(=O)N)CC(=O)O)Cc1ccccc1)CCC(=O)N)CC(C)C
Properties
Computed Properties
 
Complexity:
2700  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
12  
Heavy Atom Count:
95  
Hydrogen Bond Acceptor Count:
20  
Hydrogen Bond Donor Count:
18  
Rotatable Bond Count:
42  
XLogP3:
-4.6  

Literature

Title: Miniglucagon (MG)-generating endopeptidase, which processes glucagon into MG, is composed of N-arginine dibasic convertase and aminopeptidase B.

Journal: Endocrinology 20050201

Title: A novel method to assay proteins in blood plasma after intravenous injection of plasmid DNA.

Journal: The Tohoku journal of experimental medicine 20040301

Title: Endosomal proteolysis of glucagon at neutral pH generates the bioactive degradation product miniglucagon-(19-29).

Journal: Endocrinology 20031201

Title: Miniglucagon (glucagon 19-29): a novel regulator of the pancreatic islet physiology.

Journal: Diabetes 20020201

Title: Dalle S, et al. Miniglucagon (glucagon 19-29), a potent and efficient inhibitor of secretagogue-induced insulin release through a Ca2+ pathway. J Biol Chem. 1999 Apr 16;274(16):10869-76.

Title: Dalle S, et al. Miniglucagon (glucagon 19-29): a novel regulator of the pancreatic islet physiology. Diabetes. 2002 Feb;51(2):406-12.

Title: Pavoine C, et al. Miniglucagon [glucagon-(19-29) is a component of the positive inotropic effect of glucagon. Am J Physiol. 1991 May;260(5 Pt 1):C993-9.

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Tags:64790-15-4 Molecular Formula|64790-15-4 MDL|64790-15-4 SMILES|64790-15-4 H-Ala-Gln-Asp-Phe-Val-Gln-Trp-Leu-Met-Asn-Thr-OH