[1]Smullen,Shaun;Evans,Paul[Tetrahedron,2017,vol.73,#37,p.5493-5499]
Title: Inhibition of matrix metalloproteinase-2 by halofuginone is mediated by the Egr1 transcription factor.
Journal: Anti-cancer drugs 20121101
Title: Halofuginone prevents estrogen-deficient osteoporosis in mice.
Journal: Journal of cellular biochemistry 20121001
Title: Validation of the aging hen (Gallus gallus domesticus) as an animal model for uterine leiomyomas.
Journal: Biology of reproduction 20121001
Title: Halofugine prevents cutaneous graft versus host disease by suppression of Th17 differentiation.
Journal: Hematology (Amsterdam, Netherlands) 20120901
Title: Anticoccidial effect of halofuginone hydrobromide against Eimeria tenella with associated histology.
Journal: Parasitology research 20120801
Title: Halofuginone inhibits multiple myeloma growth in vitro and in vivo and enhances cytotoxicity of conventional and novel agents.
Journal: British journal of haematology 20120601
Title: TH17 cells are critical for skin-specific pathological injury in acute graft-versus-host disease.
Journal: Transplantation proceedings 20120601
Title: Local inhibition of angiogenesis by halofuginone coated silicone materials.
Journal: Journal of materials science. Materials in medicine 20120501
Title: Characterization of Plasmodium liver stage inhibition by halofuginone.
Journal: ChemMedChem 20120501
Title: Reduction of burn scar formation by halofuginone-eluting silicone gel sheets: a controlled study on nude mice.
Journal: Annals of plastic surgery 20120301
Title: Surgical stress resistance induced by single amino acid deprivation requires Gcn2 in mice.
Journal: Science translational medicine 20120125
Title: Halofuginone down-regulates Smad3 expression and inhibits the TGFbeta-induced expression of fibrotic markers in human corneal fibroblasts.
Journal: Molecular vision 20120101
Title: Involvement of host stroma cells and tissue fibrosis in pancreatic tumor development in transgenic mice.
Journal: PloS one 20120101
Title: Light-chain shuffling from an antigen-biased phage pool allows 185-fold improvement of an anti-halofuginone single-chain variable fragment.
Journal: Analytical biochemistry 20110301
Title: Is there any synergic effect for coadministration of mitomycin C and halofuginone on the skin wound healing?
Journal: American journal of otolaryngology 20110101
Title: Phase II AIDS Malignancy Consortium trial of topical halofuginone in AIDS-related Kaposi sarcoma.
Journal: Journal of acquired immune deficiency syndromes (1999) 20110101
Title: Halofuginone and muscular dystrophy.
Journal: Histology and histopathology 20110101
Title: Halofuginone-coated urethral catheters prevent periurethral spongiofibrosis in a rat model of urethral injury.
Journal: Journal of endourology 20110101
Title: Th17 cells and IL-17 in protective immunity to vaginal candidiasis.
Journal: PloS one 20110101
Title: Halofuginone has anti-proliferative effects in acute promyelocytic leukemia by modulating the transforming growth factor beta signaling pathway.
Journal: PloS one 20110101
Title: Efficacy of topical halofuginone in myringotomy patency.
Journal: European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery 20101101
Title: Pharmacokinetic and tissue distribution of doxycycline in broiler chickens pretreated with either: diclazuril or halofuginone.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20101101
Title: Inhibition of pancreatic stellate cell activation by halofuginone prevents pancreatic xenograft tumor development.
Journal: Pancreas 20101001
Title: The effects of methylprednisolone and halofuginone on preventing esophageal and hypopharyngeal fibrosis in delivered radiotherapy.
Journal: European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery 20100901
Title: Fibrosis inhibition and muscle histopathology improvement in laminin-alpha2-deficient mice.
Journal: Muscle & nerve 20100801
Title: Surface modification of silicone breast implants by binding the antifibrotic drug halofuginone reduces capsular fibrosis.
Journal: Plastic and reconstructive surgery 20100701
Title: Halofuginone inhibits Smad3 phosphorylation via the PI3K/Akt and MAPK/ERK pathways in muscle cells: effect on myotube fusion.
Journal: Experimental cell research 20100401
Title: The antifibrotic drug halofuginone inhibits proliferation and collagen production by human leiomyoma and myometrial smooth muscle cells.
Journal: Fertility and sterility 20100301
Title: Halofuginone, a specific inhibitor of collagen type 1 synthesis, ameliorates oxidant colonic damage in rats with experimental colitis.
Journal: Digestive diseases and sciences 20100301
Title: Halofuginone enhances the radiation sensitivity of human tumor cell lines.
Journal: Cancer letters 20100301
Title: Dihydroxylation of vinyl sulfones: stereoselective synthesis of (+)- and (-)-febrifugine and halofuginone.
Journal: The Journal of organic chemistry 20100115
Title: Halofuginone- and chitosan-coated amnion membranes demonstrate improved abdominal adhesion prevention.
Journal: TheScientificWorldJournal 20100101
Title: Systematic review and meta-analyses of the effects of halofuginone against calf cryptosporidiosis.
Journal: Preventive veterinary medicine 20091001
Title: Halofuginone mediated protection against radiation-induced leg contracture.
Journal: International journal of oncology 20090801
Title: Immunology. Amino acid addiction.
Journal: Science (New York, N.Y.) 20090605
Title: Halofuginone inhibits TH17 cell differentiation by activating the amino acid starvation response.
Journal: Science (New York, N.Y.) 20090605
Title: Inhibition of transforming growth factor beta signaling by halofuginone as a modality for pancreas fibrosis prevention.
Journal: Pancreas 20090501
Title: Effectiveness of topically applied halofuginone in management of subglottic stenosis in rats.
Journal: Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 20090501
Title: Synthesis and comparison of antimalarial activity of febrifugine derivatives including halofuginone.
Journal: Medicinal chemistry (Shariqah (United Arab Emirates)) 20090501
Title: Halofuginone prevents extracellular matrix deposition in diabetic nephropathy.
Journal: Biochemical and biophysical research communications 20090206
Title: Wound-healing modulation in upper airway stenosis-Myths and facts.
Journal: Head & neck 20090101
Title: Halofuginone has a beneficial effect on gentamicin-induced acute nephrotoxicity in rats.
Journal: Drug and chemical toxicology 20090101
Title: Prevention of muscle fibrosis and improvement in muscle performance in the mdx mouse by halofuginone.
Journal: Neuromuscular disorders : NMD 20081101
Title: An outbreak of cryptosporidiosis in a collection of Stone curlews (Burhinus oedicnemus) in Dubai.
Journal: Avian pathology : journal of the W.V.P.A 20081001
Title: The effect of halofuginone, a specific inhibitor of collagen type 1 synthesis, in the prevention of pancreatic fibrosis in an experimental model of severe hyperstimulation and obstruction pancreatitis.
Journal: The Journal of surgical research 20080701
Title: The preventive effect of halofuginone on posterior glottic stenosis in a rabbit model.
Journal: Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 20080701
Title: Halofuginone upregulates the expression of heparanase in thioacetamide-induced liver fibrosis in rats.
Journal: Laboratory investigation; a journal of technical methods and pathology 20080601
Title: Functional resolution of fibrosis in mdx mouse dystrophic heart and skeletal muscle by halofuginone.
Journal: American journal of physiology. Heart and circulatory physiology 20080401
Title: Focusing on fibrosis: halofuginone-induced functional improvement in the mdx mouse model of Duchenne muscular dystrophy.
Journal: American journal of physiology. Heart and circulatory physiology 20080401
Title: Type I collagen expression contributes to angiogenesis and the development of deeply invasive cutaneous melanoma.
Journal: International journal of cancer 20080301
Title: Involvement of ERK signaling in halofuginone-driven inhibition of fibroblast ability to contract collagen lattices.
Journal: European journal of pharmacology 20071114
Title: Development and validation of a cell culture based assay for in vitro assessment of anticryptosporidial compounds.
Journal: Parasitology research 20070601
Title: Gene expression during chemically induced liver fibrosis: effect of halofuginone on TGF-beta signaling.
Journal: Cell and tissue research 20070401
Title: Evaluation of endotoxaemia in the prognosis and treatment of scouring merino lambs.
Journal: Journal of veterinary medicine. A, Physiology, pathology, clinical medicine 20070301
Title: Inhibition of fibroblast to myofibroblast transition by halofuginone contributes to the chemotherapy-mediated antitumoral effect.
Journal: Molecular cancer therapeutics 20070201
Title: Effects of halofuginone on fibrosis formation secondary to experimentally induced subglottic trauma.
Journal: The Laryngoscope 20070201
Title: Halofuginone reduces the occurrence of renal fibrosis in 5/6 nephrectomized rats.
Journal: The Israel Medical Association journal : IMAJ 20070101
Title: Potential therapeutical effects of topical halofuginone hydrobromide in keloid management.
Journal: Medical hypotheses 20070101
Title: Effect of halofuginone, a collagen alpha1(I) inhibitor, on wound healing in normal and irradiated skin: implication for hematopoietic stem cell transplantation.
Journal: Acta haematologica 20070101
Title: Field study of the efficacy of halofuginone and decoquinate in the treatment of cryptosporidiosis in veal calves.
Journal: The Veterinary record 20061111
Title: Halofuginone inhibits NF-kappaB and p38 MAPK in activated T cells.
Journal: Journal of leukocyte biology 20060801
Title: Phase I and pharmacokinetic study of halofuginone, an oral quinazolinone derivative in patients with advanced solid tumours.
Journal: European journal of cancer (Oxford, England : 1990) 20060801
Title: Halofuginone induces matrix metalloproteinases in rat hepatic stellate cells via activation of p38 and NFkappaB.
Journal: The Journal of biological chemistry 20060602
Title: Involvement of the tyrosine phosphatase early gene of liver regeneration (PRL-1) in cell cycle and in liver regeneration and fibrosis effect of halofuginone.
Journal: Cell and tissue research 20060601
Title: Halofuginone prevents subglottic stenosis in a canine model.
Journal: The Annals of otology, rhinology, and laryngology 20060501
Title: Halofuginone suppresses the lung metastasis of chemically induced hepatocellular carcinoma in rats through MMP inhibition.
Journal: Neoplasia (New York, N.Y.) 20060401
Title: Halofuginone inhibits tumor growth in the polyoma middle T antigen mouse via a thrombospondin-1 independent mechanism.
Journal: Cancer biology & therapy 20060201
Title: Inhibition of rat renal fibroblast proliferation by halofuginone.
Journal: Nephron. Experimental nephrology 20060101
Title: Inhibition of Wilms tumor xenograft progression by halofuginone is accompanied by activation of WT-1 gene expression.
Journal: The Journal of urology 20051001
Title: Prevention of esophageal strictures in a caustic burn model using halofuginone, an inhibitor of collagen type I synthesis.
Journal: The Laryngoscope 20050901
Title: Halofuginone inhibits collagen deposition in fibrous capsules around implants.
Journal: Annals of plastic surgery 20050301
Title: Screening for the coccidiostats halofuginone and nicarbazin in egg and chicken muscle: development of an ELISA.
Journal: Food additives and contaminants 20050201
Title: Residue analysis for halofuginone in sturgeon muscle by immunoaffinity cleanup and liquid chromatography.
Journal: Journal of AOAC International 20050101
Title: Liquid chromatography-electrospray tandem mass spectrometric assay suitable for quantitation of halofuginone in plasma.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20041015
Title: Halofuginone can worsen liver fibrosis in bile duct obstructed rats.
Journal: Liver international : official journal of the International Association for the Study of the Liver 20041001
Title: Halofuginone inhibits angiogenesis and growth in implanted metastatic rat brain tumor model--an MRI study.
Journal: Neoplasia (New York, N.Y.) 20040901
Title: Suppression of hepatocellular carcinoma growth in mice by the alkaloid coccidiostat halofuginone.
Journal: European journal of cancer (Oxford, England : 1990) 20040601
Title: Ureteral replacement using small-intestinal submucosa and a collagen inhibitor in a porcine model.
Journal: Journal of endourology 20040601
Title: Potential nonhormonal therapeutics for medical treatment of leiomyomas.
Journal: Seminars in reproductive medicine 20040501
Title: Amelioration of radiation-induced fibrosis: inhibition of transforming growth factor-beta signaling by halofuginone.
Journal: The Journal of biological chemistry 20040409
Title: Halofuginone, an inhibitor of collagen synthesis by rat stellate cells, stimulates insulin-like growth factor binding protein-1 synthesis by hepatocytes.
Journal: Journal of hepatology 20040201
Title: The effect of halofuginone, a specific inhibitor of collagen type 1 synthesis, in the prevention of esophageal strictures related to caustic injury.
Journal: American journal of surgery 20040201
Title: Determination of halofuginone in eggs by liquid chromatography/tandem mass spectrometry after cleanup with immunoaffinity chromatography.
Journal: Rapid communications in mass spectrometry : RCM 20040101
Title: Halofuginone inhibits serum-stimulated pericardial tissue retraction in vitro.
Journal: Tissue engineering 20040101
Title: The use of halofuginone in limiting urethral stricture formation and recurrence: an experimental study in rabbits.
Journal: The Journal of urology 20031101
Title: Treatment with halofuginone results in marked growth inhibition of a von Hippel-Lindau pheochromocytoma in vivo.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20030901
Title: Halofuginone to treat fibrosis in chronic graft-versus-host disease and scleroderma.
Journal: Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20030701
Title: Development and validation of a method for the confirmation of halofuginone in chicken liver and eggs using electrospray tandem mass spectrometry.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20030505
Title: A medical compound derived from herbs.
Journal: Science (New York, N.Y.) 20030328
Title: Prevalence and control of bovine cryptosporidiosis in German dairy herds.
Journal: Veterinary parasitology 20030325
Title: Halofuginone inhibition of COL1A2 promoter activity via a c-Jun-dependent mechanism.
Journal: Arthritis and rheumatism 20021001
Title: Halofuginone, a collagen type I inhibitor improves liver regeneration in cirrhotic rats.
Journal: Journal of hepatology 20020901
Title: Halofuginone does not reduce fibrosis in bleomycin-induced lung injury.
Journal: Life sciences 20020823
Title: Effect of halofuginone on the development of tight skin (TSK) syndrome.
Journal: Autoimmunity 20020701
Title: Angiogenesis in bladder cancer--prognostic marker and target for future therapy.
Journal: Surgical oncology 20020601
Title: Growth inhibition of prostate cancer xenografts by halofuginone.
Journal: The Prostate 20020501
Title: Analysis of the effect of halofuginone on bleomycin-induced scleroderma.
Journal: Rheumatology (Oxford, England) 20020501
Title: Halofuginone, an inhibitor of type-I collagen synthesis and skin sclerosis, blocks transforming-growth-factor-beta-mediated Smad3 activation in fibroblasts.
Journal: The Journal of investigative dermatology 20020301
Title: Reduction in dermal fibrosis in the tight-skin (Tsk) mouse after local application of halofuginone.
Journal: Biochemical pharmacology 20011101
Title: Pharmacokinetics and tissue distribution of halofuginone (NSC 713205) in CD2F1 mice and Fischer 344 rats.
Journal: Cancer chemotherapy and pharmacology 20011101
Title: Halofuginone to prevent and treat thioacetamide-induced liver fibrosis in rats.
Journal: Hepatology (Baltimore, Md.) 20010201
Title: Novel therapy in the treatment of scleroderma.
Journal: Expert opinion on investigational drugs 20010101
Title: Determination of halofuginone and amprolium in chicken muscle and egg by liquid chromatography.
Journal: Journal of AOAC International 20010101
Title: Halofuginone: a potent inhibitor of critical steps in angiogenesis progression.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20001201
Title: The activity of halofuginone in immunosuppressed rats infected with Cryptosporidium parvum.
Journal: The Journal of antimicrobial chemotherapy 19950301
