Home Fluorides 651-80-9
651-80-9,MFCD00012385
Catalog No.:AA003FBZ

651-80-9 | 1,2,4,5-Tetrafluoro-3-(trifluoromethyl)benzene

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1g
98%
in stock  
$23.00   $16.00
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5g
98%
in stock  
$62.00   $43.00
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25g
98%
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$167.00   $117.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
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  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA003FBZ
Chemical Name:
1,2,4,5-Tetrafluoro-3-(trifluoromethyl)benzene
CAS Number:
651-80-9
Molecular Formula:
C7HF7
Molecular Weight:
218.0717
MDL Number:
MFCD00012385
SMILES:
Fc1cc(F)c(c(c1F)C(F)(F)F)F
Properties
Properties
 
BP:
112.4 °C at 760 mmHg  
Form:
Solid  
MP:
111-112 °C(lit.)  
Refractive Index:
n20/D 1.379(lit.)  
Storage:
2-8℃;  

Computed Properties
 
Complexity:
187  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
14  
Hydrogen Bond Acceptor Count:
7  
XLogP3:
3.2  

Downstream Synthesis Route

[1]Schaefer,Sascha;Wirth,Thomas[AngewandteChemie-InternationalEdition,2010,vol.49,#15,p.2786-2789]

[2]Barrow,I.;Pedler,A.E.[Tetrahedron,1976,vol.32,p.1829-1834]

[3]Matsuo,Daisuke;Yang,Xin;Hamada,Akiko;Morimoto,Kyo;Kato,Takuji;Yahiro,Masayuki;Adachi,Chihaya;Orita,Akihiro;Otera,Junzo[ChemistryLetters,2010,vol.39,#12,p.1300-1302]

651-80-9    17823-46-0   
1-H-nonafluoro-4-methyl-1,4-cyclohexadiene 
  79150-81-5 

[1]Bardin,V.V.;FurinG.G.;Yakobson,G.G.[JournalofOrganicChemistryUSSR(EnglishTranslation),1981,p.879-884][ZhurnalOrganicheskoiKhimii,1981,vol.17,#5,p.999-1004]

[2]Bardin,V.V.;FurinG.G.;Yakobson,G.G.[JournalofOrganicChemistryUSSR(EnglishTranslation),1981,p.879-884][ZhurnalOrganicheskoiKhimii,1981,vol.17,#5,p.999-1004]

[3]Bardin,V.V.;FurinG.G.;Yakobson,G.G.[JournalofOrganicChemistryUSSR(EnglishTranslation),1981,p.879-884][ZhurnalOrganicheskoiKhimii,1981,vol.17,#5,p.999-1004]

[1]Facundo,AldoA.;Arévalo,Alma;Fundora-Galano,Gabriela;Flores-Álamo,Marcos;Orgaz,Emilio;García,JuventinoJ.[NewJournalofChemistry,2019,vol.43,#18,p.6897-6908]

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[6]Krasnov;Platonov[RussianJournalofOrganicChemistry,2001,vol.37,#4,p.517-522]

[7]Schaefer,Sascha;Wirth,Thomas[AngewandteChemie-InternationalEdition,2010,vol.49,#15,p.2786-2789]

[8]Li,Junye;Zheng,Tingting;Sun,Hongjian;Li,Xiaoyan[DaltonTransactions,2013,vol.42,#36,p.13048-13053]

[9]Jaeger,AlmaD.;Ehm,Christian;Lentz,Dieter[Chemistry-AEuropeanJournal,2018,vol.24,#26,p.6769-6777]

[10]Jaeger,AlmaD.;Lentz,Dieter[ZeitschriftfurAnorganischeundAllgemeineChemie,2018,vol.644,#21,p.1229-1233]

[11]Alsop,D.J.etal.[JournaloftheChemicalSociety,1962,p.1801-1805]

[12]Krasnov,V.I.;Platonov,V.E.[RussianJournalofOrganicChemistry,1993,vol.29,#5.2,p.895-896][ZhurnalOrganicheskoiKhimii,1993,vol.29,#5,p.1078-1079]

[13]Miller,AlexeyO.;Krasnov,VyacheslavI.;Peters,Dietmar;Platonov,VyacheslavE.;Miethchen,Ralf[TetrahedronLetters,2000,vol.41,#20,p.3817-3819]

[14]Kraft,BradleyM;Jones,WilliamD[JournalofOrganometallicChemistry,2002,vol.658,#1-2,p.132-140]

[15]Tamborski,C.;Soloski,E.J.[JournalofOrganicChemistry,1966,vol.31,p.746-749]

[16]Locationinpatent:experimentalpartFischer,Peter;Goetz,Kathrin;Eichhorn,Antonius;Radius,Udo[Organometallics,2012,vol.31,#4,p.1374-1383]

[17]Locationinpatent:experimentalpartZhan,Jin-Hui;Lv,Hongbin;Yu,Yi;Zhang,Jun-Long[AdvancedSynthesisandCatalysis,2012,vol.354,#8,p.1529-1541]

[18]Lv,Hongbin;Cai,Yuan-Bo;Zhang,Jun-Long[AngewandteChemie-InternationalEdition,2013,vol.52,#11,p.3203-3207][Angew.Chem.,2013,vol.125,#11,p.3285-3289,5]

[19]Senaweera,SameeraM.;Singh,Anuradha;Weaver,JimmieD.[JournaloftheAmericanChemicalSociety,2014,vol.136,#8,p.3002-3005]

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[21]Matsunami,Asuka;Kuwata,Shigeki;Kayaki,Yoshihito[ACSCatalysis,2016,vol.6,#8,p.5181-5185]

[22]Krüger,Juliane;Leppkes,Jakob;Ehm,Christian;Lentz,Dieter[Chemistry-AnAsianJournal,2016,vol.11,#21,p.3062-3071]

[23]Lu,Jingzhi;Khetrapal,NavneetS.;Johnson,JacobA.;Zeng,XiaoCheng;Zhang,Jian[JournaloftheAmericanChemicalSociety,2016,vol.138,#49,p.15805-15808]

[24]Hein,NicholasM.;Pick,FraserS.;Fryzuk,MichaelD.[InorganicChemistry,2017,vol.56,#23,p.14513-14523]

[25]Nicholls,ThomasP.;Robertson,JohnathonC.;Gardiner,MichaelG.;Bissember,AlexC.[ChemicalCommunications,2018,vol.54,#36,p.4589-4592]

[26]Jaeger,AlmaD.;Walter,Ruben;Ehm,Christian;Lentz,Dieter[Chemistry-AnAsianJournal,2018,vol.13,#19,p.2908-2915]

[27]Lim,Soohyun;Radosevich,AlexanderT.[JournaloftheAmericanChemicalSociety,2020,vol.142,#38,p.16188-16193]

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[29]Pang,Yue;Leutzsch,Markus;Nöthling,Nils;Katzenburg,Felix;Cornella,Josep[JournaloftheAmericanChemicalSociety,2021,vol.143,#32,p.12487-12493]

[30]Zhang,Jingjing;Zhao,Xiao;Yang,Jin-Dong;Cheng,Jin-Pei[JournalofOrganicChemistry,2022,vol.87,#1,p.294-300]

[1]JournaloftheChemicalSociety,1962,p.1801-1805

[2]JournalofOrganicChemistryUSSR(EnglishTranslation),1974,vol.10,p.802-806    ZhurnalOrganicheskoiKhimii,1974,vol.10,p.799-804

[1]Bardin;Pressman[RussianChemicalBulletin,1997,vol.46,#4,p.786-788]

Literature

Title: Dichlorido[2,3,5,6-tetra-fluoro-4-(tri-fluoro-meth-yl)phenyl-κC]bis-(tri-methyl-phosphine-κP)cobalt(III).

Journal: Acta crystallographica. Section E, Structure reports online 20100501

Title: Synthesis and reactivity of low-coordinate iron(II) fluoride complexes and their use in the catalytic hydrodefluorination of fluorocarbons.

Journal: Journal of the American Chemical Society 20050601

Title: Synthesis of (Z)-4-hydroxytamoxifen and (Z)-2-[4-[1-(p-hydroxyphenyl)-2-phenyl]-1butenyl]phenoxyacetic acid.

Journal: The Journal of organic chemistry 20020628

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Tags:651-80-9 Molecular Formula|651-80-9 MDL|651-80-9 SMILES|651-80-9 1,2,4,5-Tetrafluoro-3-(trifluoromethyl)benzene |Fluorinated_Building_Blocks