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655-35-6,MFCD00717478
Catalog No.:AA00EF36

655-35-6 | CARBOCROMENE HYDROCHLORIDE

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Purity
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10mg
3 weeks  
$350.00   $245.00
- +
25mg
3 weeks  
$466.00   $326.00
- +
100mg
3 weeks  
$1,200.00   $840.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00EF36
Chemical Name:
CARBOCROMENE HYDROCHLORIDE
CAS Number:
655-35-6
Molecular Formula:
C20H28ClNO5
Molecular Weight:
397.8930
MDL Number:
MFCD00717478
SMILES:
CCOC(=O)COc1ccc2c(c1)oc(=O)c(c2C)CCN(CC)CC.Cl
NSC Number:
110430
Properties
Computed Properties
 
Complexity:
526  
Covalently-Bonded Unit Count:
2  
Heavy Atom Count:
27  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
10  

Literature

Title: Synthesis and vasorelaxant and platelet antiaggregatory activities of a new series of 6-halo-3-phenylcoumarins.

Journal: Molecules (Basel, Switzerland) 20100112

Title: Protective effects of a coumarin derivative in diabetic rats.

Journal: Investigative ophthalmology & visual science 20090801

Title: Retinal and systemic pharmacokinetics of the anti-inflammatory drug cloricromene following oral administration in the rat and rabbit.

Journal: Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20070601

Title: Enhancement of availability of cloricromene at brain level by a lipophilic prodrug.

Journal: The Journal of pharmacy and pharmacology 20060701

Title: Cloricromene, a coumarine derivative, reduced the development of periodontitis in rats.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20060401

Title: Preparation and characterization of eudragit retard nanosuspensions for the ocular delivery of cloricromene.

Journal: AAPS PharmSciTech 20060301

Title: Cloricromene effect on the enzyme activities of the tryptophan-nicotinic acid pathway in diabetic/hyperlipidemic rabbits.

Journal: Life sciences 20060118

Title: Cloricromene in endotoxemia: role of NF-kappaB.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20040801

Title: Eudragit RL100 nanoparticle system for the ophthalmic delivery of cloricromene.

Journal: The Journal of pharmacy and pharmacology 20040701

Title: In vitro evaluation of PLA nanoparticles containing a lipophilic drug in water-soluble or insoluble form.

Journal: International journal of pharmaceutics 20040618

Title: A protective effect of the synthetic coumarine derivative Cloricromene against DNB-colitis in the rat.

Journal: Life sciences 20040416

Title: Effects of cloricromene, a coumarin derivative, on endotoxin-induced uveitis in Lewis rats.

Journal: Investigative ophthalmology & visual science 20030301

Title: Preparation and characterization of solid lipid nanoparticles containing cloricromene.

Journal: Drug delivery 20030101

Title: Simultaneous determination of cloricromene and its active metabolite in rabbit aqueous humor by high-performance liquid chromatography.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20020205

Title: Effect of estrogen replacement therapy on distribution of myocardial blood flow in female anesthetized rabbits.

Journal: American journal of physiology. Heart and circulatory physiology 20010901

Title: Cloricromene, a semi-synthetic coumarin derivative, inhibits tumor necrosis factor-alpha production at a pre-transcriptional level.

Journal: European journal of pharmacology 20010427

Title: Intradermal injection vs. oral treatment of tinnitus.

Journal: Therapie 20010101

Title: Protective actions of carbocromene against amitriptyline-induced cardiotoxicity in anesthetized rats.

Journal: Archives internationales de pharmacodynamie et de therapie 19860101

Title: Cardioprotective effects of carbocromen in awake and anesthetized dogs with amitriptyline poisoning.

Journal: Journal of cardiovascular pharmacology 19850101

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