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70476-82-3,MFCD00242943
Catalog No.:AA003S22

70476-82-3 | Mitoxantrone dihydrochloride

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1mg
98%
in stock  
$8.00   $6.00
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10mg
98%
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$22.00   $15.00
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25mg
98%(HPLC)powder
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$43.00   $30.00
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50mg
98%
in stock  
$44.00   $31.00
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500mg
98%(HPLC)powder
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$377.00   $264.00
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1g
98%(HPLC)powder
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$713.00   $499.00
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  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA003S22
Chemical Name:
Mitoxantrone dihydrochloride
CAS Number:
70476-82-3
Molecular Formula:
C22H30Cl2N4O6
Molecular Weight:
517.4028
MDL Number:
MFCD00242943
SMILES:
OCCNCCNc1ccc(c2c1C(=O)c1c(C2=O)c(O)ccc1O)NCCNCCO.Cl.Cl
Properties
Properties
 
Form:
Solid  
MP:
203-205 C  
Storage:
Inert atmosphere;Room Temperature;  

Computed Properties
 
Complexity:
571  
Covalently-Bonded Unit Count:
3  
Heavy Atom Count:
34  
Hydrogen Bond Acceptor Count:
10  
Hydrogen Bond Donor Count:
10  
Rotatable Bond Count:
12  

Upstream Synthesis Route

[1]Farmaco,EdizioneScientifica,1987,vol.42,#3,p.219-226

[1]Farmaco,EdizioneScientifica,1987,vol.42,#3,p.219-226

Downstream Synthesis Route

[1]CurrentPatentAssignee:ABCAMPLC-US6656917,2003,B1Locationinpatent:Pagecolumn33

70476-82-3    3150-24-1   
mitoxantronedi-galactosideconjugate 

[1]CurrentPatentAssignee:ABCAMPLC-US6656917,2003,B1Locationinpatent:Pagecolumn34

70476-82-3   
CASUnavailable 

[1]CurrentPatentAssignee:PFIZERINC-US4296030,1981,A

70476-82-3   
CASUnavailable 

[1]CurrentPatentAssignee:PFIZERINC-US4296030,1981,A

[2]CurrentPatentAssignee:PFIZERINC-US4296030,1981,A

1180-95-6    70476-82-3   
2C26H45NO6S*C22H28N4O6 

[1]Molecules,2017,vol.22

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Title: Rituximab serum concentrations during immuno-chemotherapy of follicular lymphoma correlate with patient gender, bone marrow infiltration and clinical response.

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Journal: Medical oncology (Northwood, London, England) 20120601

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Journal: The AAPS journal 20120601

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Journal: Paediatric drugs 20120601

Title: Failure event types and prognostic factors after node-positive breast cancer in patients treated by adjuvant chemotherapy: impact on follow-up.

Journal: Bulletin du cancer 20120601

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Title: A population-based study of prostate cancer chemotherapy.

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Journal: Der Nervenarzt 20111001

Title: Pegylated liposomal doxorubicin in combination with dexamethasone and bortezomib (VMD) or lenalidomide (RMD) in multiple myeloma pretreated patients.

Journal: Annals of hematology 20110901

Title: Stability of cognitive functions under mitoxantrone therapy in patients with progressive multiple sclerosis: a pilot analysis.

Journal: Clinical neurology and neurosurgery 20110901

Title: Intra-arterial mitoxantrone delivery in rabbits: an optical pharmacokinetic study.

Journal: Neurosurgery 20110901

Title: MS Forum/MS Over the Past 17 Years.

Journal: International MS journal 20110901

Title: ABCG2 is required to control the sonic hedgehog pathway in side population cells with stem-like properties.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20110901

Title: Randomized phase II trial of Custirsen (OGX-011) in combination with docetaxel or mitoxantrone as second-line therapy in patients with metastatic castrate-resistant prostate cancer progressing after first-line docetaxel: CUOG trial P-06c.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20110901

Title: [A case of neuromyelitis optica with varicella zoster virus meningitis during mitoxantrone treatment].

Journal: Rinsho shinkeigaku = Clinical neurology 20110901

Title: [Docetaxel-based chemotherapy for hormone-refractory prostate cancer in Japanese patients : experience in a single institute].

Journal: Hinyokika kiyo. Acta urologica Japonica 20110901

Title: [Regulation mechanism of breast cancer resistance protein by toremifene to reverse BCRP-mediated multidrug resistance in breast cancer cells].

Journal: Zhonghua zhong liu za zhi [Chinese journal of oncology] 20110901

Title: Structure-activity relationship and molecular mechanisms of ethyl 2-amino-6-(3,5-dimethoxyphenyl)-4-(2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate (CXL017) and its analogues.

Journal: Journal of medicinal chemistry 20110825

Title: A newborn with Pierre Robin sequence after preconceptional mitoxantrone exposure of a female with multiple sclerosis.

Journal: Journal of the neurological sciences 20110815

Title: Mitoxantrone inhibits HIF-1α expression in a topoisomerase II-independent pathway.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20110801

Title: Use of mitoxantrone in neuromyelitis optica.

Journal: Archives of neurology 20110801

Title: What's up with down syndrome and leukemia-A lot!

Journal: Pediatric blood & cancer 20110715

Title: Continuous and high-dose cytarabine combined chemotherapy in children with down syndrome and acute myeloid leukemia: Report from the Japanese children's cancer and leukemia study group (JCCLSG) AML 9805 down study.

Journal: Pediatric blood & cancer 20110715

Title: Mitoxantrone induced impediment of histone acetylation and structural flexibility of the protein.

Journal: Cell biochemistry and biophysics 20110701

Title: Fludarabine and cytarabine in patients with acute myeloid leukemia refractory to two different courses of front-line chemotherapy.

Journal: Leukemia research 20110701

Title: Long-term safety profile of mitoxantrone in a French cohort of 802 multiple sclerosis patients: a 5-year prospective study.

Journal: Multiple sclerosis (Houndmills, Basingstoke, England) 20110701

Title: MDM2 antagonist nutlin-3a reverses mitoxantrone resistance by inhibiting breast cancer resistance protein mediated drug transport.

Journal: Biochemical pharmacology 20110701

Title: Glucocorticoid regulation of placental breast cancer resistance protein (Bcrp1) in the mouse.

Journal: Reproductive sciences (Thousand Oaks, Calif.) 20110701

Title: Cytarabine dose of 36 g/m² compared with 12 g/m² within first consolidation in acute myeloid leukemia: results of patients enrolled onto the prospective randomized AML96 study.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110701

Title: GALNT14 SNP as a potential predictor of response to combination chemotherapy using 5-FU, mitoxantrone and cisplatin in advanced HCC.

Journal: Pharmacogenomics 20110701

Title: A pH-responsive cleavage route based on a metal-organic coordination bond.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20110620

Title: Gemtuzumab ozogamicin, mitoxantrone, and etoposide in newly diagnosed acute myeloid leukemia patients with persistent leukemia after a course of induction therapy.

Journal: Annals of hematology 20110601

Title: Long-term follow-up of tandem high-dose therapy with autologous stem cell support for adults with high-risk age-adjusted international prognostic index aggressive non-Hodgkin Lymphomas: a GOELAMS pilot study.

Journal: Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20110601

Title: Tumor necrosis factor alpha induces stronger cytotoxicity in ABCG2-overexpressing resistant breast cancer cells compared with their drug-sensitive parental line.

Journal: DNA and cell biology 20110601

Title: Multiple sclerosis: current treatment algorithms.

Journal: Current opinion in neurology 20110601

Title: Increased incidence of central nervous system hemorrhages in patients with secondary acute promyelocytic leukemia after treatment of multiple sclerosis with mitoxantrone?

Journal: Haematologica 20110601

Title: Use of diagnostic tests and procedures for disease-modifying therapy users and non-disease-modifying therapy users with multiple sclerosis.

Journal: Expert review of neurotherapeutics 20110601

Title: Adjuvant androgen deprivation for high-risk prostate cancer after radical prostatectomy: SWOG S9921 study.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110520

Title: Asymmetric enzymatic glycosylation of mitoxantrone.

Journal: Organic letters 20110520

Title: Clinical outcomes of natalizumab-associated progressive multifocal leukoencephalopathy.

Journal: Neurology 20110517

Title: Synthesis and biological evaluation of 4-arylcoumarin analogues of combretastatins. Part 2.

Journal: Journal of medicinal chemistry 20110512

Title: 5,7-Dimethoxyflavone and multiple flavonoids in combination alter the ABCG2-mediated tissue distribution of mitoxantrone in mice.

Journal: Pharmaceutical research 20110501

Title: [Specific palatal infiltration in B-cell chronic lymphocytic leukemia].

Journal: Actas dermo-sifiliograficas 20110501

Title: Managing MS in a changing treatment landscape.

Journal: Journal of neurology 20110501

Title: Functional improvement and symptom management in multiple sclerosis: clinical efficacy of current therapies.

Journal: The American journal of managed care 20110501

Title: Sildenafil reverses ABCB1- and ABCG2-mediated chemotherapeutic drug resistance.

Journal: Cancer research 20110415

Title: Total tau and S100b proteins in different types of multiple sclerosis and during immunosuppressive treatment with mitoxantrone.

Journal: Acta neurologica Scandinavica 20110401

Title: Drug-induced Sweet's syndrome after mitoxantrone therapy in a patient with multiple sclerosis.

Journal: Multiple sclerosis (Houndmills, Basingstoke, England) 20110401

Title: Efficacy and safety of mitoxantrone in patients with highly relapsing neuromyelitis optica.

Journal: Archives of neurology 20110401

Title: Five Chinese pediatric patients with leukemias possibly arising from immature natural killer cells: clinical features and courses.

Journal: Pediatric hematology and oncology 20110401

Title: TROPIC: Phase III trial of cabazitaxel for the treatment of metastatic castration-resistant prostate cancer.

Journal: Future oncology (London, England) 20110401

Title: Phase 1 and pharmacokinetic study of bolus-infusion flavopiridol followed by cytosine arabinoside and mitoxantrone for acute leukemias.

Journal: Blood 20110324

Title: Risk of acute promyelocytic leukemia in multiple sclerosis: coding variants of DNA repair genes.

Journal: Neurology 20110322

Title: Race and intensity of post-remission therapy in acute myeloid leukemia.

Journal: Leukemia research 20110301

Title: Primary mediastinal B-cell lymphoma treated with CHOP-like chemotherapy with or without rituximab: results of the Mabthera International Trial Group study.

Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20110301

Title: Midtreatment 18F-fluorodeoxyglucose positron-emission tomography in aggressive non-Hodgkin lymphoma.

Journal: Cancer 20110301

Title: Salvaging AML with CLAG: novel option, or more of the same?

Journal: Leukemia research 20110301

Title: Salvage chemotherapy regimens for acute myeloid leukemia: Is one better? Efficacy comparison between CLAG and MEC regimens.

Journal: Leukemia research 20110301

Title: A phase I/II study of combined chemotherapy with mitoxantrone and uracil/tegafur for advanced hepatocellular carcinoma.

Journal: Japanese journal of clinical oncology 20110301

Title: Investigating the enhancement of cisplatin cytotoxicity on 5637 cells by combination with mogoltacin.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20110301

Title: Cabazitaxel: a new drug for metastatic prostate cancer.

Journal: Asian journal of andrology 20110301

Title: A randomized phase II trial of fludarabine, cyclophosphamide and mitoxantrone (FCM) with or without rituximab in previously treated chronic lymphocytic leukaemia.

Journal: British journal of haematology 20110301

Title: Infusional mitoxantrone plus bolus melphalan as a stem cell transplant conditioning regimen for multiple myeloma.

Journal: Cancer investigation 20110301

Title: Inhibition of unwinding and ATPase activities of pea MCM6 DNA helicase by actinomycin and nogalamycin.

Journal: Plant signaling & behavior 20110301

Title: Role of second-line systemic treatment post-docetaxel in metastatic castrate resistant prostate cancer- current strategies and future directions.

Journal: Anti-cancer agents in medicinal chemistry 20110301

Title: Schedule treatment design and quantitative in vitro evaluation of chemotherapeutic combinations for metastatic prostate cancer therapy.

Journal: Cancer chemotherapy and pharmacology 20110201

Title: Potential role of cyclooxygenase-2 on the regulation of the drug efflux transporter ABCG2 in breast cancer cell lines.

Journal: Journal of cancer research and clinical oncology 20110201

Title: A phase I study of OSI-461 in combination with mitoxantrone in patients with advanced solid tumors potentially responsive to mitoxantrone.

Journal: Cancer chemotherapy and pharmacology 20110201

Title: Spectral studies on the molecular interaction of anticancer drug mitoxantrone with CTAB micelles.

Journal: Journal of pharmaceutical sciences 20110201

Title: Oxidative metabolism of the anti-cancer agent mitoxantrone by horseradish, lacto-and lignin peroxidase.

Journal: Biochimie 20110201

Title: Molecular genetic basis for fluoroquinolone-induced retinal degeneration in cats.

Journal: Pharmacogenetics and genomics 20110201

Title: Long-term follow-up of pediatric patients treated with mitoxantrone for multiple sclerosis.

Journal: Neuropediatrics 20110201

Title: Infusion of HLA-mismatched peripheral blood stem cells improves the outcome of chemotherapy for acute myeloid leukemia in elderly patients.

Journal: Blood 20110120

Title: Early lymphocyte recovery after intensive timed sequential chemotherapy for acute myelogenous leukemia: peripheral oligoclonal expansion of regulatory T cells.

Journal: Blood 20110113

Title: Cabazitaxel for castration-resistant prostate cancer.

Journal: Lancet (London, England) 20110108

Title: Cabazitaxel for castration-resistant prostate cancer.

Journal: Lancet (London, England) 20110108

Title: Liposomal imatinib-mitoxantrone combination: formulation development and therapeutic evaluation in an animal model of prostate cancer.

Journal: The Prostate 20110101

Title: Mitoxantrone is expelled by the ABCG2 multidrug transporter directly from the plasma membrane.

Journal: Biochimica et biophysica acta 20110101

Title: [Clinical, radiographic, prognostic and therapeutic aspects of demelinating disease with tumefactive demyelinating lesions].

Journal: Revue neurologique 20110101

Title: Knockdown of caveolin-1 decreases activity of breast cancer resistance protein (BCRP/ABCG2) and increases chemotherapeutic sensitivity.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20110101

Title: Interaction of mitoxantrone, as an anticancer drug, with chromatin proteins, core histones and H1, in solution.

Journal: International journal of biological macromolecules 20110101

Title: Mitoxantrone in combination with an inhibitor of DNA-dependent protein kinase: a potential therapy for high risk B-cell chronic lymphocytic leukaemia.

Journal: British journal of haematology 20110101

Title: Tolerability and acceptance of prolonged low/delayed mitoxantrone regimens in patients with worsening multiple sclerosis.

Journal: European neurology 20110101

Title: Biochemical and pharmacological effects of mitoxantrone and acetyl-L-carnitine in mice with a solid form of Ehrlich tumour.

Journal: Chemotherapy 20110101

Title: Intra-arterial mitoxantrone/paclitaxel in angiosarcoma of the lower limb associated with chronic lymphedema (Stewart-Treves syndrome) in a patient with cervical cancer.

Journal: European journal of dermatology : EJD 20110101

Title: Structure and function of ABCG2-rich extracellular vesicles mediating multidrug resistance.

Journal: PloS one 20110101

Title: Current disease-modifying treatment of multiple sclerosis.

Journal: The Mount Sinai journal of medicine, New York 20110101

Title: Molecular modeling study of interaction of anthracenedione class of drug mitoxantrone and its analogs with DNA tetrameric sequences.

Journal: Advances in experimental medicine and biology 20110101

Title: Influence of anticancer therapy on oxidation phenotype and acetylation phenotype in patients with acute myeloblastic leukemia.

Journal: Pharmacological reports : PR 20110101

Title: [Energetics of complex formation of the DNA hairpin structure d(GCGAAGC) with aromatic ligands].

Journal: Biofizika 20110101

Title: Retrospective comparison between a regular and a split-dose protocol of 5-fluorouracil, cisplatin, and mitoxantrone for the treatment of far advanced hepatocellular carcinoma.

Journal: BMC cancer 20110101

Title: [Severe skin reaction with mucous membrane inflammation during MINE chemotherapy].

Journal: Annales de dermatologie et de venereologie 20110101

Title: The effect of ATM and ERK1/2 inhibition on mitoxantrone-induced cell death of leukaemic cells.

Journal: Folia biologica 20110101

Title: Glycolysis inhibition inactivates ABC transporters to restore drug sensitivity in malignant cells.

Journal: PloS one 20110101

Title: Mitoxantrone in combination with a DNA-PK inhibitor: possible therapy of promyelocytic leukaemia resistant forms.

Journal: Folia biologica 20110101

Title: Interaction of human multidrug and toxin extrusion 1 (MATE1) transporter with antineoplastic agents.

Journal: Drug metabolism and drug interactions 20110101

Title: [Treatment of elderly patients with non-Hodgkin's lymphoma].

Journal: Likars'ka sprava 20110101

Title: Complete remission and early death after intensive chemotherapy in patients aged 60 years or older with acute myeloid leukaemia: a web-based application for prediction of outcomes.

Journal: Lancet (London, England) 20101211

Title: Effect of mitoxantrone on outcome of children with first relapse of acute lymphoblastic leukaemia (ALL R3): an open-label randomised trial.

Journal: Lancet (London, England) 20101211

Title: Mitoxantrone in first-relapse paediatric ALL: the ALL R3 trial.

Journal: Lancet (London, England) 20101211

Title: Flower-like hierarchically nanostructured hydroxyapatite hollow spheres: facile preparation and application in anticancer drug cellular delivery.

Journal: Chemistry, an Asian journal 20101203

Title: Effect of mitoxantrone on proliferation dynamics and cell-cycle progression.

Journal: Bioscience reports 20101201

Title: Reduced dose-limiting toxicity of intraperitoneal mitoxantrone chemotherapy using cardiolipin-based anionic liposomes.

Journal: Nanomedicine : nanotechnology, biology, and medicine 20101201

Title: Mitoxantrone for worsening multiple sclerosis: tolerability, toxicity, adherence and efficacy in the clinical setting.

Journal: Clinical neurology and neurosurgery 20101201

Title: Comparative study of mitoxantrone efficacy profile in patients with relapsing-remitting and secondary progressive multiple sclerosis.

Journal: Multiple sclerosis (Houndmills, Basingstoke, England) 20101201

Title: A predictive ligand-based Bayesian model for human drug-induced liver injury.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20101201

Title: Receptor for activated C-kinase 1 regulates the cell surface expression and function of ATP binding cassette G2.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20101201

Title: Identification of specific inhibitors for a trypanosomatid RNA editing reaction.

Journal: RNA (New York, N.Y.) 20101201

Title: [Mitoxantrone-related acute leukemia by multiple sclerosis. Case report and practical approach by unclear cytopenia].

Journal: Der Nervenarzt 20101201

Title: A Phase II trial of gemcitabine and mitoxantrone for patients with acute myeloid leukemia in first relapse.

Journal: Clinical lymphoma, myeloma & leukemia 20101201

Title: [Pharmacodynamics, pharmacokinetics and tissue distribution of liposomal mitoxantrone hydrochloride].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20101201

Title: The anti-oxidative role of ABCG2 in corneal epithelial cells.

Journal: Investigative ophthalmology & visual science 20101101

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: Second-line mitoxantrone, etoposide, and cytarabine for acute myeloid leukemia: a single-center experience.

Journal: American journal of hematology 20101101

Title: Expression of noncoding vault RNA in human malignant cells and its importance in mitoxantrone resistance.

Journal: Molecular cancer research : MCR 20101101

Title: New biomarkers probing depth of cell senescence assessed by laser scanning cytometry.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20101101

Title: TRAIL-expressing mesenchymal stem cells kill the putative cancer stem cell population.

Journal: British journal of cancer 20101101

Title: Tubulin-targeting chemotherapy impairs androgen receptor activity in prostate cancer.

Journal: Cancer research 20101015

Title: On-line chemiluminescence determination of mitoxantrone by capillary electrophoresis.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20101015

Title: New anthracenedione derivatives with improved biological activity by virtue of stable drug-DNA adduct formation.

Journal: Journal of medicinal chemistry 20101014

Title: Differential inhibition of murine Bcrp1/Abcg2 and human BCRP/ABCG2 by the mycotoxin fumitremorgin C.

Journal: European journal of pharmacology 20101010

Title: Cabazitaxel in prostate cancer: stretching a string.

Journal: Lancet (London, England) 20101002

Title: Prednisone plus cabazitaxel or mitoxantrone for metastatic castration-resistant prostate cancer progressing after docetaxel treatment: a randomised open-label trial.

Journal: Lancet (London, England) 20101002

Title: Mitoxantrone treatment in multiple sclerosis induces TH2-type cytokines.

Journal: Acta neurologica Scandinavica 20101001

Title: Transcriptional modulation of BCRP gene to reverse multidrug resistance by toremifene in breast adenocarcinoma cells.

Journal: Breast cancer research and treatment 20101001

Title: Efficacy of oncolytic mutants targeting pRb and p53 pathways is synergistically enhanced when combined with cytotoxic drugs in prostate cancer cells and tumor xenografts.

Journal: Human gene therapy 20101001

Title: Efficacy and safety of the combination of rituximab, fludarabine, and mitoxantrone for rituximab-naive, recurrent/refractory follicular non-Hodgkin lymphoma with high tumor burden: a multicenter phase 2 trial by the Groupe d'Etude des Lymphomes de l'Adulte (GELA) and Groupe Ouest Est des Leucémies et Autres Maladies du Sang (GOELAMS).

Journal: Cancer 20100915

Title: Treatment outcome of radiotherapy alone versus radiochemotherapy in early stage nasal natural killer/T-cell lymphoma.

Journal: Medical oncology (Northwood, London, England) 20100901

Title: A pilot study of carboplatin and mitoxantrone in blast crisis of chronic myeloid leukemia.

Journal: Medical oncology (Northwood, London, England) 20100901

Title: Long-term outcome of mesna, ifosfamide, mitoxantrone, etoposide (MINE) regimen as a consolidation in patients with aggressive non-Hodgkin lymphoma responding to CHOP.

Journal: Medical oncology (Northwood, London, England) 20100901

Title: Off-line memory consolidation impairments in multiple sclerosis patients receiving high-dose corticosteroid treatment mirror consolidation impairments in depression.

Journal: Psychoneuroendocrinology 20100901

Title: Determination of mitoxantrone in rat plasma by liquid chromatography-tandem mass spectrometry method: Application to a pharmacokinetic study.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20100815

Title: Beta-casein-based nanovehicles for oral delivery of chemotherapeutic drugs: drug-protein interactions and mitoxantrone loading capacity.

Journal: Nanomedicine : nanotechnology, biology, and medicine 20100801

Title: Constructing a conceptual framework of patient-reported outcomes for metastatic hormone-refractory prostate cancer.

Journal: Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research 20100801

Title: BCRP/ABCG2 confers anticancer drug resistance without covalent dimerization.

Journal: Cancer science 20100801

Title: Analysis of t(15;17) chromosomal breakpoint sequences in therapy-related versus de novo acute promyelocytic leukemia: association of DNA breaks with specific DNA motifs at PML and RARA loci.

Journal: Genes, chromosomes & cancer 20100801

Title: Characterization and optimization of a novel protein-protein interaction biosensor high-content screening assay to identify disruptors of the interactions between p53 and hDM2.

Journal: Assay and drug development technologies 20100801

Title: Preparation, characterization, and in vivo evaluation of mitoxantrone-loaded, folate-conjugated albumin nanoparticles.

Journal: Archives of pharmacal research 20100801

Title: Rational design, synthesis, and DNA binding properties of novel sequence-selective peptidyl congeners of ametantrone.

Journal: ChemMedChem 20100705

Title: Clinical activity of sequential flavopiridol, cytosine arabinoside, and mitoxantrone for adults with newly diagnosed, poor-risk acute myelogenous leukemia.

Journal: Leukemia research 20100701

Title: Effects of single and multiple flavonoids on BCRP-mediated accumulation, cytotoxicity and transport of mitoxantrone in vitro.

Journal: Pharmaceutical research 20100701

Title: Sequential flavopiridol, mitoxantrone and cytosine arabinoside for newly diagnosed poor risk acute myeloid leukemia. What to do next?

Journal: Leukemia research 20100701

Title: Overcoming drug resistance in mantle cell lymphoma using a combination of dose-dense and intense therapy.

Journal: Cancer investigation 20100701

Title: Effects of the isoflavonoid biochanin A on the transport of mitoxantrone in vitro and in vivo.

Journal: Biopharmaceutics & drug disposition 20100701

Title: Autologous haematopoietic stem cell transplantation for secondary progressive multiple sclerosis: an exploratory cost-effectiveness analysis.

Journal: Bone marrow transplantation 20100601

Title: Aggregation of spectrin and PKCtheta is an early hallmark of fludarabine/mitoxantrone/dexamethasone-induced apoptosis in Jurkat T and HL60 cells.

Journal: Molecular and cellular biochemistry 20100601

Title: Kinetic analysis of the cooperation of P-glycoprotein (P-gp/Abcb1) and breast cancer resistance protein (Bcrp/Abcg2) in limiting the brain and testis penetration of erlotinib, flavopiridol, and mitoxantrone.

Journal: The Journal of pharmacology and experimental therapeutics 20100601

Title: Cardiotoxicity and other adverse events associated with mitoxantrone treatment for MS.

Journal: Neurology 20100601

Title: Treatment of therapy-related myeloid neoplasms with high-dose cytarabine/mitoxantrone followed by hematopoietic stem cell transplant.

Journal: Leukemia & lymphoma 20100601

Title: A single dose pegfilgrastim for supporting neutrophil recovery in patients treated for high-risk acute myeloid leukemia by the EMA 2000 schedule.

Journal: Hematology (Amsterdam, Netherlands) 20100601

Title: DNA topoisomerases and their poisoning by anticancer and antibacterial drugs.

Journal: Chemistry & biology 20100528

Title: Coupled spectral and electrochemical evaluation of the anticancer drug mitoxantrone-sodium dodecyl sulfate interaction.

Journal: International journal of pharmaceutics 20100510

Title: Immunotherapy and multiple sclerosis: The devil is in the details.

Journal: Neurology 20100504

Title: Evidence Report: The efficacy and safety of mitoxantrone (Novantrone) in the treatment of multiple sclerosis: Report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology.

Journal: Neurology 20100504

Title: Pharmacokinetics and biliary excretion of mitoxantrone in rats.

Journal: Journal of pharmaceutical sciences 20100501

Title: Genotoxic stress causes the accumulation of the splicing regulator Sam68 in nuclear foci of transcriptionally active chromatin.

Journal: Nucleic acids research 20100501

Title: Phase I study of valspodar (PSC-833) with mitoxantrone and etoposide in refractory and relapsed pediatric acute leukemia: a report from the Children's Oncology Group.

Journal: Pediatric blood & cancer 20100501

Title: Adherence to recommended dosing and monitoring for mitoxantrone in patients with multiple sclerosis: a healthcare claims database study supplemented with medical records--the RETRO study.

Journal: Pharmacoepidemiology and drug safety 20100501

Title: [Diagnosis and therapy in multiple sclerosis].

Journal: Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS 20100501

Title: Inhibition of transcription factor assembly and structural stability on mitoxantrone binding with DNA.

Journal: Bioscience reports 20100421

Title: Magnetic resonance evidence of cerebellar cortical pathology in multiple sclerosis.

Journal: Journal of neurology, neurosurgery, and psychiatry 20100401

Title: KLK5 gene expression is severely upregulated in androgen-independent prostate cancer cells after treatment with the chemotherapeutic agents docetaxel and mitoxantrone.

Journal: Biological chemistry 20100401

Title: Clinical effect of neutralizing antibodies to interferon beta that persist long after cessation of therapy for multiple sclerosis.

Journal: Archives of neurology 20100401

Title: Phase 1/2 study of preoperative docetaxel and mitoxantrone for high-risk prostate cancer.

Journal: Cancer 20100401

Title: (-)-Epigallocatechin-3-gallate downregulates Pg-P and BCRP in a tamoxifen resistant MCF-7 cell line.

Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20100401

Title: Rituximab plus dose-reduced cyclophosphamide, mitoxantrone, vincristine, and prednisolone are effective in elderly patients with diffuse large B-cell lymphoma of the thyroid.

Journal: Thyroid : official journal of the American Thyroid Association 20100401

Title: Histologic changes associated with neoadjuvant chemotherapy are predictive of nodal metastases in patients with high-risk prostate cancer.

Journal: American journal of clinical pathology 20100401

Title: Evaluation of indomethacin and dexamethasone effects on BCRP-mediated drug resistance in MCF-7 parental and resistant cell lines.

Journal: Drug and chemical toxicology 20100401

Title: Multiple sclerosis: closing in on an oral treatment.

Journal: Nature 20100318

Title: Mutational analysis of threonine 402 adjacent to the GXXXG dimerization motif in transmembrane segment 1 of ABCG2.

Journal: Biochemistry 20100316

Title: Severe cardiac failure in a patient with multiple sclerosis following low-dose mitoxantrone treatment.

Journal: Neurology 20100316

Title: The human breast cancer resistance protein (BCRP/ABCG2) shows conformational changes with mitoxantrone.

Journal: Structure (London, England : 1993) 20100314

Title: [Pharmacological treatment of multiple sclerosis].

Journal: Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20100311

Title: Fludarabine, cyclophosphamide, mitoxantrone plus rituximab (FCM-R) in frontline CLL <70 Years.

Journal: Leukemia research 20100301

Title: CCL2 is induced by chemotherapy and protects prostate cancer cells from docetaxel-induced cytotoxicity.

Journal: The Prostate 20100301

Title: Intrathecal chemotherapy and meningeal relapses in myelomonocytic AML. A single institution experience.

Journal: American journal of hematology 20100301

Title: Advantage of MIDAM protocol in treatment of elderly patients with refractory and relapsing acute myeloid leukemia.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100301

Title: Heart transplant in a childhood leukemia survivor: a case report.

Journal: Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation 20100301

Title: Evaluation of a multidrug chemotherapy protocol with mitoxantrone based maintenance (CHOP-MA) for the treatment of canine lymphoma.

Journal: Veterinary and comparative oncology 20100301

Title: HPLC analysis of mitoxantrone in mouse plasma and tissues: application in a pharmacokinetic study.

Journal: Journal of pharmaceutical and biomedical analysis 20100205

Title: Beta-casein nanovehicles for oral delivery of chemotherapeutic drugs.

Journal: Nanomedicine : nanotechnology, biology, and medicine 20100201

Title: The development of risk groups in men with metastatic castration-resistant prostate cancer based on risk factors for PSA decline and survival.

Journal: European journal of cancer (Oxford, England : 1990) 20100201

Title: Attempts to optimize induction and consolidation treatment in acute myeloid leukemia: results of the MRC AML12 trial.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100201

Title: Multidrug resistance in breast cancer cells during epithelial-mesenchymal transition is modulated by breast cancer resistant protein.

Journal: Chinese journal of cancer 20100201

Title: [Effect of physical exercise on the efficacy of mitoxantrone-loaded nanoparticles in treating early breast cancer].

Journal: Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi 20100201

Title: Evidence for direct involvement of epirubicin in the formation of chromosomal translocations in t(15;17) therapy-related acute promyelocytic leukemia.

Journal: Blood 20100114

Title: Mitoxantrone and cytotoxic drugs' mechanisms of action.

Journal: Neurology 20100105

Title: Tyrosine kinase inhibitors and multidrug resistance proteins: interactions and biological consequences.

Journal: Cancer chemotherapy and pharmacology 20100101

Title: The beta-carboline alkaloid harmine inhibits BCRP and can reverse resistance to the anticancer drugs mitoxantrone and camptothecin in breast cancer cells.

Journal: Phytotherapy research : PTR 20100101

Title: Regulation of BCRP (ABCG2) and P-glycoprotein (ABCB1) by cytokines in a model of the human blood-brain barrier.

Journal: Cellular and molecular neurobiology 20100101

Title: Regulation of gene expression in brain tissues of rats repeatedly treated by the highly abused opioid agonist, oxycodone: microarray profiling and gene mapping analysis.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20100101

Title: VNCOP-B plus rituximab therapy in elderly patients with aggressive B-cell non-Hodgkin lymphoma: a multicenter experience.

Journal: Archives of gerontology and geriatrics 20100101

Title: Inhibition of receptor tyrosine kinase signalling by small molecule agonist of T-cell protein tyrosine phosphatase.

Journal: BMC cancer 20100101

Title: [Clinical study of sequential high-dose chemotherapy with in vivo rituximab-purged stem cell autografting for mantle cell lymphoma].

Journal: [Rinsho ketsueki] The Japanese journal of clinical hematology 20100101

Title: A randomized phase II trial of mitoxantrone, estramustine and vinorelbine or bcl-2 modulation with 13-cis retinoic acid, interferon and paclitaxel in patients with metastatic castrate-resistant prostate cancer: ECOG 3899.

Journal: Journal of translational medicine 20100101

Title: [Patients older than 80 years with de novo acute myeloid leukemias without erythroblastic and/or megakaryocytic dysplasia achieve complete remission and longer survival after classical chemotherapy 3 + 7].

Journal: Vnitrni lekarstvi 20100101

Title: [Evaluation of fludarabine-containing regimens versus immunochemotherapy for chronic lymphocytic leukemia].

Journal: Terapevticheskii arkhiv 20100101

Title: Mitoxantrone loaded superparamagnetic nanoparticles for drug targeting: a versatile and sensitive method for quantification of drug enrichment in rabbit tissues using HPLC-UV.

Journal: Journal of biomedicine & biotechnology 20100101

Title: TTFields alone and in combination with chemotherapeutic agents effectively reduce the viability of MDR cell sub-lines that over-express ABC transporters.

Journal: BMC cancer 20100101

Title: Biclonal follicular lymphoma: histological, clinical and molecular characteristics.

Journal: Pathology 20100101

Title: Pharmacokinetic comparability of Prolastin®-C to Prolastin® in alpha₁-antitrypsin deficiency: a randomized study.

Journal: BMC clinical pharmacology 20100101

Title: Effects of chitosan coating on physical properties and pharmacokinetic behavior of mitoxantrone liposomes.

Journal: International journal of nanomedicine 20100101

Title: Luteinizing hormone-releasing hormone receptor-mediated delivery of mitoxantrone using LHRH analogs modified with PEGylated liposomes.

Journal: International journal of nanomedicine 20100101

Title: Dynamic vs static ABCG2 inhibitors to sensitize drug resistant cancer cells.

Journal: PloS one 20100101

Title: Citrulline as a marker for chemotherapy induced mucosal barrier injury in pediatric patients.

Journal: Pediatric blood & cancer 20091215

Title: A randomized multicenter phase II clinical trial of mitoxantrone-loaded nanoparticles in the treatment of 108 patients with unresected hepatocellular carcinoma.

Journal: Nanomedicine : nanotechnology, biology, and medicine 20091201

Title: Restoring immune suppression in the multiple sclerosis brain.

Journal: Progress in neurobiology 20091201

Title: Mitoxantrone-mediated apoptotic B16-F1 cells induce specific anti-tumor immune response.

Journal: Cellular & molecular immunology 20091201

Title: Tumor-specific cytotoxicity and type of cell death induced by gefitinib in oral squamous cell carcinoma cell lines.

Journal: Anticancer research 20091201

Title: Chemotherapy induces ATP release from tumor cells.

Journal: Cell cycle (Georgetown, Tex.) 20091115

Title: Mitoxantrone analogues as ligands for a stem-loop structure of tau pre-mRNA.

Journal: Journal of medicinal chemistry 20091112

Title: Daunorubicin versus mitoxantrone versus idarubicin as induction and consolidation chemotherapy for adults with acute myeloid leukemia: the EORTC and GIMEMA Groups Study AML-10.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20091110

Title: Additional chromosomal abnormalities and their prognostic significance in adult Philadelphia-positive acute lymphoblastic leukemia: with or without imatinib in chemotherapy.

Journal: Annals of hematology 20091101

Title: Efficacious but insidious: a retrospective analysis of fludarabine-induced myelotoxicity using long-term culture-initiating cells in 100 follicular lymphoma patients.

Journal: Experimental hematology 20091101

Title: Multiple sclerosis. Part 2: ophthalmic issues in MS therapy.

Journal: Current opinion in ophthalmology 20091101

Title: Revision of the risk of secondary leukaemia after mitoxantrone in multiple sclerosis populations is required.

Journal: Multiple sclerosis (Houndmills, Basingstoke, England) 20091101

Title: Mitoxantrone and etoposide in patients with newly diagnosed acute myeloid leukemia with persistent leukemia after a course of therapy with cytarabine and idarubicin.

Journal: Leukemia & lymphoma 20091101

Title: [Rescue treatments for multiple sclerosis].

Journal: Rinsho shinkeigaku = Clinical neurology 20091101

Title: [Treatment of NMO].

Journal: Rinsho shinkeigaku = Clinical neurology 20091101

Title: The cytotoxic effects of gemtuzumab ozogamicin (mylotarg) in combination with conventional antileukemic agents by isobologram analysis in vitro.

Journal: Anticancer research 20091101

Title: Surface modification of mitoxantrone-loaded PLGA nanospheres with chitosan.

Journal: Colloids and surfaces. B, Biointerfaces 20091015

Title: Structure-activity relationship and molecular mechanisms of ethyl 2-amino-4-(2-ethoxy-2-oxoethyl)-6-phenyl-4h-chromene-3-carboxylate (sha 14-1) and its analogues.

Journal: Journal of medicinal chemistry 20091008

Title: Results of a Phase II trial of gemcitabine, mitoxantrone, and rituximab in relapsed or refractory mantle cell lymphoma.

Journal: Investigational new drugs 20091001

Title: Interleukin-1 beta and tumor necrosis factor-alpha increase ABCG2 expression in MCF-7 breast carcinoma cell line and its mitoxantrone-resistant derivative, MCF-7/MX.

Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20091001

Title: ABCG2 is related with the grade of glioma and resistance to mitoxantone, a chemotherapeutic drug for glioma.

Journal: Journal of cancer research and clinical oncology 20091001

Title: B-type natriuretic peptide as a marker of subclinical heart injury during mitoxantrone therapy in MS patients--preliminary study.

Journal: Clinical neurology and neurosurgery 20091001

Title: Incidence and outcome of patients with diffuse large B cell lymphoma with marrow involvement and preliminary experience of an adult acute lymphoblastic leukemia protocol (NEALL VI) in cyclophosphamide, doxorubicin, vincristine, and prednisolone--rituximab refractory patients.

Journal: Leukemia & lymphoma 20091001

Title: Lack of ABCG2 expression and side population properties in human pluripotent stem cells.

Journal: Stem cells (Dayton, Ohio) 20091001

Title: Escape from hsa-miR-519c enables drug-resistant cells to maintain high expression of ABCG2.

Journal: Molecular cancer therapeutics 20091001

Title: Pharmacokinetic-pharmacodynamic modeling of manganese after a single intravenous infusion of mangafodipir in patients with acute alcoholic hepatitis.

Journal: Therapeutic drug monitoring 20091001

Title: Treatment of multiple sclerosis: role of natalizumab.

Journal: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20091001

Title: Mitoxantrone: benefits and risks in multiple sclerosis patients.

Journal: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20091001

Title: Severe cardiac failure in a patient with multiple sclerosis following low-dose mitoxantrone treatment.

Journal: Neurology 20090922

Title: Rituximab, fludarabine, cyclophosphamide, and mitoxantrone: a new, highly active chemoimmunotherapy regimen for chronic lymphocytic leukemia.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090920

Title: Expression of multidrug resistance proteins in prostate cancer is related with cell sensitivity to chemotherapeutic drugs.

Journal: The Prostate 20090915

Title: Mitochondrial expression and functional activity of breast cancer resistance protein in different multiple drug-resistant cell lines.

Journal: Cancer research 20090915

Title: Substrate-dependent bidirectional modulation of P-glycoprotein-mediated drug resistance by erlotinib.

Journal: Cancer science 20090901

Title: [Patients with metastatic hormone-refractory prostate cancer. Second-line chemotherapy with mitoxantrone plus prednisone].

Journal: Der Urologe. Ausg. A 20090901

Title: Dose-dependent melanonychia by mitoxantrone.

Journal: Multiple sclerosis (Houndmills, Basingstoke, England) 20090901

Title: ABC-transporter gene-polymorphisms are potential pharmacogenetic markers for mitoxantrone response in multiple sclerosis.

Journal: Brain : a journal of neurology 20090901

Title: Poly(ethylene glycol)-stabilized silver nanoparticles for bioanalytical applications of SERS spectroscopy.

Journal: The Analyst 20090901

Title: Optimisation of replication-selective oncolytic adenoviral mutants in combination with chemotherapeutics.

Journal: Journal of B.U.ON. : official journal of the Balkan Union of Oncology 20090901

Title: Bendamustine in chronic lymphocytic leukemia: the future is combination therapy.

Journal: Leukemia & lymphoma 20090901

Title: Bendamustine/mitoxantrone/rituximab: a short remission induction chemoimmunotherapy for elderly patients with relapsed or refractory chronic lymphocytic leukemia.

Journal: Leukemia & lymphoma 20090901

Title: Breast cancer resistance protein (BCRP/ABCG2): new inhibitors and QSAR studies by a 3D linear solvation energy approach.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20090812

Title: Continuous 24-h monitoring of electrocardiogram during anthracycline-based therapy in acute leukemia.

Journal: Leukemia research 20090801

Title: Dynamic assessment of mitoxantrone resistance and modulation of multidrug resistance by valspodar (PSC833) in multidrug resistance human cancer cells.

Journal: The Journal of pharmacology and experimental therapeutics 20090801

Title: Serial combination therapy: is immune modulation in multiple sclerosis enhanced by initial immune suppression?

Journal: Multiple sclerosis (Houndmills, Basingstoke, England) 20090801

Title: [Successful induction of complete remission by gemtuzumab ozogamicin following chemotherapy in three patients with relapsed or refractory acute myeloid leukemia].

Journal: [Rinsho ketsueki] The Japanese journal of clinical hematology 20090801

Title: Survival time of dogs with inflammatory mammary cancer treated with palliative therapy alone or palliative therapy plus chemotherapy.

Journal: The Veterinary record 20090718

Title: Inhibitors of VIM-2 by screening pharmacologically active and click-chemistry compound libraries.

Journal: Bioorganic & medicinal chemistry 20090715

Title: Identification of inhibitors of ABCG2 by a bioluminescence imaging-based high-throughput assay.

Journal: Cancer research 20090715

Title: Shortened and intensified MJMA: an effective salvage therapy for relapsed and refractory lymphomas and a strong mobilizer of PBSCs.

Journal: Bone marrow transplantation 20090701

Title: Idiopathic hyperammonemia (IHA) after dose-dense induction chemotherapy for acute myeloid leukemia: Case report and review of the literature.

Journal: Leukemia research 20090701

Title: Use of arsenic trioxide in secondary acute promyelocytic leukemia developing after treatment of multiple sclerosis with mitoxantrone.

Journal: Leukemia & lymphoma 20090701

Title: Identification of a pancreatic stellate cell population with properties of progenitor cells: new role for stellate cells in the pancreas.

Journal: The Biochemical journal 20090626

Title: Tie2-mediated multidrug resistance in malignant gliomas is associated with upregulation of ABC transporters.

Journal: Oncogene 20090618

Title: Cyclophosphamide therapy in pediatric multiple sclerosis.

Journal: Neurology 20090616

Title: Phase I study of ixabepilone, mitoxantrone, and prednisone in patients with metastatic castration-resistant prostate cancer previously treated with docetaxel-based therapy: a study of the department of defense prostate cancer clinical trials consortium.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090610

Title: Doxorubicin and mitoxantrone drug eluting beads for the treatment of experimental peritoneal carcinomatosis in colorectal cancer.

Journal: International journal of cancer 20090601

Title: What is the real impact of bone pain on survival in patients with metastatic hormone-refractory prostate cancer treated with docetaxel?

Journal: BJU international 20090601

Title: MicroRNA-328 negatively regulates the expression of breast cancer resistance protein (BCRP/ABCG2) in human cancer cells.

Journal: Molecular pharmacology 20090601

Title: Drug-induced torsades de pointes: data mining of the public version of the FDA Adverse Event Reporting System (AERS).

Journal: Pharmacoepidemiology and drug safety 20090601

Title: DNA damage response as a biomarker in treatment of leukemias.

Journal: Cell cycle (Georgetown, Tex.) 20090601

Title: Targeting of epidermal growth factor receptor (EGFR)-expressing tumor cells with sterically stabilized affibody liposomes (SAL).

Journal: Bioconjugate chemistry 20090601

Title: Acquired acute myelogenous leukemia after therapy for acute promyelocytic leukemia with t(15;17): a case report and review of the literature.

Journal: Puerto Rico health sciences journal 20090601

Title: A dual-fluorescence high-throughput cell line system for probing multidrug resistance.

Journal: Assay and drug development technologies 20090601

Title: Effect and prognostic analysis of treatment for acute myeloid leukemia using Chinese drugs combined with chemotherapy.

Journal: Chinese journal of integrative medicine 20090601

Title: Pentostatin treatment combinations in chronic lymphocytic leukemia.

Journal: Clinical advances in hematology & oncology : H&O 20090601

Title: Isolation and identification of a new impurity in mitoxantrone hydrochloride.

Journal: Die Pharmazie 20090601

Title: Regimen containing perarubicin for the treatment of newly diagnosed young patients with acute myeloid leukemia.

Journal: Ai zheng = Aizheng = Chinese journal of cancer 20090601

Title: Structural basis for stabilization of the tau pre-mRNA splicing regulatory element by novantrone (mitoxantrone).

Journal: Chemistry & biology 20090529

Title: Prostate-specific antigen progression predicts overall survival in patients with metastatic prostate cancer: data from Southwest Oncology Group Trials 9346 (Intergroup Study 0162) and 9916.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090520

Title: Retrovirally transduced murine T lymphocytes expressing FasL mediate effective killing of prostate cancer cells.

Journal: Cancer gene therapy 20090501

Title: Anthracycline-fludarabine-containing regimens with or without rituximab in the treatment of patients with advanced follicular lymphoma.

Journal: Cancer 20090501

Title: Incidence of intestinal obstruction following intraperitoneal chemotherapy for ovarian tubal and peritoneal malignancies.

Journal: Gynecologic oncology 20090501

Title: [Toxicity and efficacy of intermittent docetaxel chemotherapy for hormone refractory prostate cancer].

Journal: Aktuelle Urologie 20090501

Title: [Stem cell therapy in multiple sclerosis: a clinical update].

Journal: Zeitschrift fur Rheumatologie 20090501

Title: HIV and anal cancer outcomes: a single institution's experience.

Journal: Diseases of the colon and rectum 20090501

Title: [Mitoxantrone for the treatment of patients with multiple sclerosis].

Journal: Brain and nerve = Shinkei kenkyu no shinpo 20090501

Title: Dose-dense induction with sequential high-dose cytarabine and mitoxantone (S-HAM) and pegfilgrastim results in a high efficacy and a short duration of critical neutropenia in de novo acute myeloid leukemia: a pilot study of the AMLCG.

Journal: Blood 20090423

Title: Single-dose mitoxantrone in combination with continuous infusion intermediate-dose cytarabine plus etoposide for treatment of refractory or early relapsed acute myeloid leukemia.

Journal: Leukemia research 20090401

Title: Assessment of mitoxantrone-induced cardiotoxicity in patients with multiple sclerosis: a tissue Doppler echocardiographic analysis.

Journal: Echocardiography (Mount Kisco, N.Y.) 20090401

Title: Therapy-related acute leukaemia with Mitoxantrone: what is the risk and can we minimise it?

Journal: Multiple sclerosis (Houndmills, Basingstoke, England) 20090401

Title: The use of higher dose clofarabine in adults with relapsed acute lymphoblastic leukemia.

Journal: American journal of hematology 20090401

Title: Rituximab-associated acute thrombocytopenia: an under-diagnosed phenomenon.

Journal: American journal of hematology 20090401

Title: Immune-induced epithelial to mesenchymal transition in vivo generates breast cancer stem cells.

Journal: Cancer research 20090401

Title: CE can identify small molecules that selectively target soluble oligomers of amyloid beta protein and display antifibrillogenic activity.

Journal: Electrophoresis 20090401

Title: Hematology: germinal center or nongerminal center DLBCL?

Journal: Nature reviews. Clinical oncology 20090401

Title: [Bacillus cereus sepsis and subarachnoid hemorrhage following consolidation chemotherapy for acute myelogenous leukemia].

Journal: [Rinsho ketsueki] The Japanese journal of clinical hematology 20090401

Title: Characterization of the inhibition of breast cancer resistance protein-mediated efflux of mitoxantrone by pharmaceutical excipients.

Journal: International journal of pharmaceutics 20090331

Title: PTEN/PI3K/Akt pathway regulates the side population phenotype and ABCG2 activity in glioma tumor stem-like cells.

Journal: Cell stem cell 20090306

Title: Rapid complete cytogenetic remission after upfront dasatinib monotherapy in a patient with a NUP214-ABL1-positive T-cell acute lymphoblastic leukemia.

Journal: Leukemia 20090301

Title: Identification of a potential 'hotspot' DNA region in the RUNX1 gene targeted by mitoxantrone in therapy-related acute myeloid leukemia with t(16;21) translocation.

Journal: Genes, chromosomes & cancer 20090301

Title: CTLA-4 genotype and relapse incidence in patients with acute myeloid leukemia in first complete remission after induction chemotherapy.

Journal: Leukemia 20090301

Title: Chemotherapeutic impact on pain and global health-related quality of life in hormone-refractory prostate cancer: Dynamically Modified Outcomes (DYNAMO) analysis of a randomized controlled trial.

Journal: Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation 20090301

Title: Synthesis and cytotoxic properties of 4,11-bis[(aminoethyl)amino]anthra[2,3-b]thiophene-5,10-diones, novel analogues of antitumor anthracene-9,10-diones.

Journal: Bioorganic & medicinal chemistry 20090301

Title: Cellular folate status modulates the expression of BCRP and MRP multidrug transporters in cancer cell lines from different origins.

Journal: Molecular cancer therapeutics 20090301

Title: Biphenotypic acute leukemia treated with acute myeloid leukemia regimens: a case series.

Journal: Journal of the National Medical Association 20090301

Title: How effective is natalizumab as second-line treatment for multiple sclerosis in daily clinical praxis?

Journal: European journal of neurology 20090301

Title: Efficacy of natalizumab in multiple sclerosis patients with high disease activity: a Danish nationwide study.

Journal: European journal of neurology 20090301

Title: Drug rash with eosinophilia and systemic signs syndrome in a patient with multiple sclerosis.

Journal: Clinical therapeutics 20090301

Title: Ni2+-mediated mitoxantrone encapsulation: improved efficacy of fast release formulation.

Journal: International journal of pharmaceutics 20090223

Title: Phylogenetic conservation of the preapoptotic calreticulin exposure pathway from yeast to mammals.

Journal: Cell cycle (Georgetown, Tex.) 20090215

Title: The epidermal growth factor tyrosine kinase inhibitor AG1478 and erlotinib reverse ABCG2-mediated drug resistance.

Journal: Oncology reports 20090201

Title: The hypoxia-activated ProDrug AQ4N penetrates deeply in tumor tissues and complements the limited distribution of mitoxantrone.

Journal: Cancer research 20090201

Title: Treatment of PC3 prostate cancer cells with mitoxantrone, etoposide, doxorubicin and carboplatin induces distinct alterations in the expression of kallikreins 5 and 11.

Journal: Thrombosis and haemostasis 20090201

Title: Concepts of induction and escalation therapy in multiple sclerosis.

Journal: Journal of the neurological sciences 20090201

Title: Long-term experience with induction treatment regimens in multiple sclerosis.

Journal: Journal of the neurological sciences 20090201

Title: Immunosuppression followed by immunomodulation.

Journal: Journal of the neurological sciences 20090201

Title: Experimental evidence for killing the resistant cells and raising the efficacy and decreasing the toxicity of cytostatics and irradiation by mixtures of the agents of the passive antitumor defense system in the case of various tumor and normal cell lines in vitro.

Journal: Cancer biotherapy & radiopharmaceuticals 20090201

Title: [Therapeutic effect and toxicity of compound vincristine liposome on breast cancer in nude mice].

Journal: Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi 20090201

Title: Complex t(2;21;8)(p12;q22;q22): a variant t(8;21) in a patient with acute myeloid leukemia (AML-M2).

Journal: Cancer genetics and cytogenetics 20090115

Title: The relationship of body mass index and serum testosterone with disease outcomes in men with castration-resistant metastatic prostate cancer.

Journal: Prostate cancer and prostatic diseases 20090101

Title: A combination therapy with fludarabine, mitoxantrone and rituximab induces complete immunophenotypical remission in B-cell prolymphocytic leukaemia.

Journal: Annals of hematology 20090101

Title: Value of information and value of implementation: application of an analytic framework to inform resource allocation decisions in metastatic hormone-refractory prostate cancer.

Journal: Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research 20090101

Title: Mitoxantrone does not restore the impaired suppressive function of natural regulatory T cells in patients suffering from multiple sclerosis. A longitudinal ex vivo and in vitro study.

Journal: European neurology 20090101

Title: Higher liposomal membrane fluidity enhances the in vitro antitumor activity of folate-targeted liposomal mitoxantrone.

Journal: Molecular pharmaceutics 20090101

Title: Anticancer drug-DNA interactions measured using a photoinduced electron-transfer mechanism based on luminescent quantum dots.

Journal: Analytical chemistry 20090101

Title: Molecular expression and functional evidence of a drug efflux pump (BCRP) in human corneal epithelial cells.

Journal: Current eye research 20090101

Title: Successfully conservative treatment of large cervical choriocarcinoma with profuse vaginal bleeding.

Journal: Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20090101

Title: Studies on the binding affinity of anticancer drug mitoxantrone to chromatin, DNA and histone proteins.

Journal: Journal of biomedical science 20090101

Title: Inflammatory (B) symptoms are independent predictors of myelosuppression from chemotherapy in Non-Hodgkin Lymphoma (NHL) patients--analysis of data from a British National Lymphoma Investigation phase III trial comparing CHOP to PMitCEBO.

Journal: BMC cancer 20090101

Title: Primary cutaneous large B-cell lymphoma, leg type, successfully treated with rituximab plus chemotherapy.

Journal: European journal of dermatology : EJD 20090101

Title: A novel two mode-acting inhibitor of ABCG2-mediated multidrug transport and resistance in cancer chemotherapy.

Journal: PloS one 20090101

Title: Efficacy and safety of mitoxantrone, as an initial therapy, in multiple sclerosis: experience in an Indian tertiary care setting.

Journal: Neurology India 20090101

Title: Invited commentary. Efficacy and safety of mitoxantrone, as an initial therapy, in multiple sclerosis: experience in an Indian tertiary care setting.

Journal: Neurology India 20090101

Title: Invited commentary. Efficacy and safety of mitoxantrone, as an initial therapy, in multiple sclerosis: experience in an Indian tertiary care setting.

Journal: Neurology India 20090101

Title: [Use of mitoxantrone in the treatment of multiple sclerosis].

Journal: Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20090101

Title: [Combined therapy of aggressive remitted multiple sclerosis with mitoxantrone in combination with copaxone].

Journal: Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20090101

Title: Mitroxantrone in multiple sclerosis.

Journal: Neurology India 20090101

Title: Membrane topology of the human breast cancer resistance protein (BCRP/ABCG2) determined by epitope insertion and immunofluorescence.

Journal: Biochemistry 20081230

Title: Interaction of mitoxantrone with human serum albumin: spectroscopic and molecular modeling studies.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20081218

Title: A phase II study of high-dose calcitriol combined with mitoxantrone and prednisone for androgen-independent prostate cancer.

Journal: BJU international 20081201

Title: High level functional expression of the ABCG2 multidrug transporter in undifferentiated human embryonic stem cells.

Journal: Biochimica et biophysica acta 20081201

Title: [Use of mitoxantrone in early multiple sclerosis with malignant disease course. Observational study in 30 patients with clinical and MRI outcomes after one year].

Journal: Revue neurologique 20081201

Title: Clustering of organ-specific autoimmunity: a case presentation of multiple sclerosis and connective tissue disorders.

Journal: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20081201

Title: Treatment of invasive aspergillosis with nonmyeloablative allogeneic stem cell transplantation: the hunter becomes the hunted.

Journal: American journal of hematology 20081201

Title: Repeated injection of pegylated liposomal antitumour drugs induces the disappearance of the rapid distribution phase.

Journal: The Journal of pharmacy and pharmacology 20081201

Title: Interactions of mitoxantrone with duplex and triplex DNA studied by electrospray ionization mass spectrometry.

Journal: Rapid communications in mass spectrometry : RCM 20081201

Title: Adjuvant intra-arterial chemotherapy and radiotherapy versus surgery alone in resectable pancreatic and periampullary cancer: a prospective randomized controlled trial.

Journal: Annals of surgery 20081201

Title: Early interferon beta treatment in multiple sclerosis: nursing care implications of the BENEFIT study.

Journal: The Journal of neuroscience nursing : journal of the American Association of Neuroscience Nurses 20081201

Title: New therapeutical approaches for non muscle invasive bladder cancer.

Journal: Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica 20081201

Title: Multiple sclerosis and the TNFRSF1A R92Q mutation: clinical characteristics of 21 cases.

Journal: Neurology 20081125

Title: Dimethoxyaurones: Potent inhibitors of ABCG2 (breast cancer resistance protein).

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20081115

Title: Long-term disease-free survival after gemtuzumab, intermediate-dose cytarabine, and mitoxantrone in patients with CD33(+) primary resistant or relapsed acute myeloid leukemia.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20081110

Title: The therapy of multiple sclerosis with immune-modulating or immunosuppressive drug. A critical evaluation based upon evidence based parameters and published systematic reviews.

Journal: Clinical neurology and neurosurgery 20081101

Title: A preliminary study on MeO-PEG-PLGA-PEG-OMe nanoparticles as intravenous carriers.

Journal: Journal of biomedical materials research. Part A 20081101

Title: Frequency and risk factors of mitoxantrone-induced amenorrhea in multiple sclerosis: the FEMIMS study.

Journal: Multiple sclerosis (Houndmills, Basingstoke, England) 20081101

Title: Timed sequential induction chemotherapy and risk-adapted postremission therapy for acute myelogenous leukemia.

Journal: American journal of hematology 20081101

Title: Overexpression of cell surface cytokeratin 8 in multidrug-resistant MCF-7/MX cells enhances cell adhesion to the extracellular matrix.

Journal: Neoplasia (New York, N.Y.) 20081101

Title: [A case of stage IV breast cancer in which a long-term no change state (NC) was attained by a combination of S-1 and TAM following AC-T as a primary systemic therapy (PST)].

Journal: Gan to kagaku ryoho. Cancer & chemotherapy 20081101

Title: Future research directions for the treatment of AML.

Journal: Clinical advances in hematology & oncology : H&O 20081101

Title: Dexamethasone down-regulates ABCG2 expression levels in breast cancer cells.

Journal: Biochemical and biophysical research communications 20081024

Title: Molecular analysis of t(15;17) genomic breakpoints in secondary acute promyelocytic leukemia arising after treatment of multiple sclerosis.

Journal: Blood 20081015

Title: Acute promyelocytic leukemic involvement of the optic nerves following mitoxantrone treatment for multiple sclerosis.

Journal: Journal of the neurological sciences 20081015

Title: Survival and PSA response of patients in the TAX 327 study who crossed over to receive docetaxel after mitoxantrone or vice versa.

Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20081001

Title: Encapsulation of mitoxantrone into pegylated SUVs enhances its antineoplastic efficacy.

Journal: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20081001

Title: Lipid composition and grafted PEG affect in vivo activity of liposomal mitoxantrone.

Journal: International journal of pharmaceutics 20081001

Title: Folate deprivation induces BCRP (ABCG2) expression and mitoxantrone resistance in Caco-2 cells.

Journal: International journal of cancer 20081001

Title: Addition of rituximab to standard chemotherapy improves the survival of both the germinal center B-cell-like and non-germinal center B-cell-like subtypes of diffuse large B-cell lymphoma.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20081001

Title: Predictive factors of outcome and tumor response to systemic chemotherapy in patients with metastatic hepatocellular carcinoma.

Journal: Japanese journal of clinical oncology 20081001

Title: Phosphorylation of p53 on Ser15 during cell cycle caused by Topo I and Topo II inhibitors in relation to ATM and Chk2 activation.

Journal: Cell cycle (Georgetown, Tex.) 20081001

Title: [Choice of early and escalation treatment options for multiple sclerosis].

Journal: Der Nervenarzt 20081001

Title: Antipsychotic drugs inhibit the function of breast cancer resistance protein.

Journal: Basic & clinical pharmacology & toxicology 20081001

Title: Glatiramer acetate after mitoxantrone induction improves MRI markers of lesion volume and permanent tissue injury in MS.

Journal: Journal of neurology 20081001

Title: Basic and escalating immunomodulatory treatments in multiple sclerosis: current therapeutic recommendations.

Journal: Journal of neurology 20081001

Title: Co-expression of cytokeratin 8 and breast cancer resistant protein indicates a multifactorial drug-resistant phenotype in human breast cancer cell line.

Journal: Life sciences 20080926

Title: Modulation of breast cancer resistance protein (BCRP/ABCG2) by non-basic chalcone analogues.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20080902

Title: Lobeline, a piperidine alkaloid from Lobelia can reverse P-gp dependent multidrug resistance in tumor cells.

Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20080901

Title: The co-translocation of ERp57 and calreticulin determines the immunogenicity of cell death.

Journal: Cell death and differentiation 20080901

Title: Equitoxicity of bolus and infusional etoposide: results of a multicenter randomised trial of the German High-Grade Non-Hodgkins Lymphoma Study Group (DSHNHL) in elderly patients with refractory or relapsing aggressive non-Hodgkin lymphoma using the CEMP regimen (cisplatinum, etoposide, mitoxantrone and prednisone).

Journal: Annals of hematology 20080901

Title: Systemic therapy after first-line docetaxel in metastatic castration-resistant prostate cancer.

Journal: Current opinion in supportive and palliative care 20080901

Title: Induction and add-on therapy with mitoxantrone and interferon beta in multiple sclerosis.

Journal: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20080901

Title: Neuromyelitis optica: diagnosis, pathogenesis, and treatment.

Journal: Current neurology and neuroscience reports 20080901

Title: Fas-mediated killing of primary prostate cancer cells is increased by mitoxantrone and docetaxel.

Journal: Molecular cancer therapeutics 20080901

Title: Profiling SLCO and SLC22 genes in the NCI-60 cancer cell lines to identify drug uptake transporters.

Journal: Molecular cancer therapeutics 20080901

Title: Clinical investigations in aggressive non-Hodgkin lymphoma.

Journal: Clinical advances in hematology & oncology : H&O 20080901

Title: Mitoxantrone-related acute leukemia in two MS patients.

Journal: Acta neurologica Belgica 20080901

Title: Perspective on 'Chemotherapy for advanced prostate cancer: 25 years later': is it a mirage or an oasis?

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080820

Title: A role for topoisomerase II alpha in the formation of radiation-induced chromatid breaks.

Journal: British journal of cancer 20080819

Title: ERP57 membrane translocation dictates the immunogenicity of tumor cell death by controlling the membrane translocation of calreticulin.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20080815

Title: Copper ion-mediated liposomal encapsulation of mitoxantrone: the role of anions in drug loading, retention and release.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20080807

Title: The Canadian Uro-Oncology Group multicentre phase II study of docetaxel administered every 3 weeks with prednisone in men with metastatic hormone-refractory prostate cancer progressing after mitoxantrone/prednisone.

Journal: BJU international 20080805

Title: Four new cases of therapy-related acute promyelocytic leukemia after mitoxantrone.

Journal: Neurology 20080805

Title: The effects of methylprednisolone and mitoxantrone on CCL5-induced migration of lymphocytes in multiple sclerosis.

Journal: Acta neurologica Scandinavica 20080801

Title: Azathioprine in multiple sclerosis.

Journal: Mini reviews in medicinal chemistry 20080801

Title: [Effects of mitoxantrone on the activity of human protein kinase CK2 holoenzyme].

Journal: Ai zheng = Aizheng = Chinese journal of cancer 20080801

Title: Phase I evaluation of gemcitabine, mitoxantrone, and their effect on plasma disposition of fludarabine in patients with relapsed or refractory acute myeloid leukemia.

Journal: Leukemia & lymphoma 20080801

Title: The postchemotherapy PSA surge syndrome.

Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20080701

Title: Comment on: 'Non-Hodgkin's lymphoma in very elderly patients over 80 years. A descriptive analysis of clinical presentation and outcome'.

Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20080701

Title: Systemic nonhormonal management of advanced prostate cancer and its likely impact on patients' survival and quality of life.

Journal: Anti-cancer drugs 20080701

Title: Frontline therapy for chronic lymphocytic leukemia: the dilemma continues.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20080701

Title: Synthesis, cytotoxicity, DNA interaction, and topoisomerase II inhibition properties of novel indeno[2,1-c]quinolin-7-one and indeno[1,2-c]isoquinolin-5,11-dione derivatives.

Journal: Journal of medicinal chemistry 20080626

Title: Randomized trial of high-dose adjuvant chemotherapy with autologous hematopoietic stem-cell support versus standard-dose chemotherapy in breast cancer patients with 10 or more positive lymph nodes: overall survival after 6 years of follow-up.

Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20080601

Title: CNOP (mitoxantrone) chemotherapy is inferior to CHOP (doxorubicin) in the treatment of patients with aggressive non-Hodgkin lymphoma (meta-analysis).

Journal: European journal of haematology 20080601

Title: Mechanisms and strategies to overcome chemotherapy resistance in metastatic breast cancer.

Journal: Cancer treatment reviews 20080601

Title: Glatiramer acetate after induction therapy with mitoxantrone in relapsing multiple sclerosis.

Journal: Multiple sclerosis (Houndmills, Basingstoke, England) 20080601

Title: Kinetics of histone H2AX phosphorylation and Chk2 activation in A549 cells treated with topotecan and mitoxantrone in relation to the cell cycle phase.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20080601

Title: CI-994 (N-acetyl-dinaline) in combination with conventional anti-cancer agents is effective against acute myeloid leukemia in vitro and in vivo.

Journal: Oncology reports 20080601

Title: Effective multiple sclerosis management through improved patient assessment.

Journal: The Journal of neuroscience nursing : journal of the American Association of Neuroscience Nurses 20080601

Title: Pharmacologic management of multiple sclerosis.

Journal: Urologic nursing 20080601

Title: Acute myeloid leukemia induced by mitoxantrone treatment for aggressive multiple sclerosis.

Journal: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20080601

Title: Assessment of DNA double-strand breaks and gammaH2AX induced by the topoisomerase II poisons etoposide and mitoxantrone.

Journal: Mutation research 20080510

Title: Safety and efficacy of gemtuzumab ozogamicin in combination with chemotherapy for pediatric acute myeloid leukemia: a report from the Children's Oncology Group.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080510

Title: Re: Adaptive therapy for androgen-independent prostate cancer: a randomized selection trial of four regimens.

Journal: Journal of the National Cancer Institute 20080507

Title: Single-step doxorubicin-selected cancer cells overexpress the ABCG2 drug transporter through epigenetic changes.

Journal: British journal of cancer 20080506

Title: Treatment of recurrent glioblastoma: can local delivery of mitoxantrone improve survival?

Journal: Journal of neuro-oncology 20080501

Title: A theoretical study on interactions between mitoxantrone as an anticancer drug and DNA: application in drug design.

Journal: Chemical biology & drug design 20080501

Title: Rapid and sustained clearance of circulating lymphoma cells after chemotherapy plus rituximab: clinical significance of quantitative t(14;18) PCR monitoring in advanced stage follicular lymphoma patients.

Journal: British journal of haematology 20080501

Title: Treatment of hormone-refractory prostate cancer with docetaxel or mitoxantrone: relationships between prostate-specific antigen, pain, and quality of life response and survival in the TAX-327 study.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20080501

Title: Acute promyelocytic leukemia after mitoxantrone therapy for multiple sclerosis.

Journal: Cancer genetics and cytogenetics 20080415

Title: Liposomal coencapsulated fludarabine and mitoxantrone for lymphoproliferative disorder treatment.

Journal: Journal of pharmaceutical sciences 20080401

Title: Variation of serum uric acid levels in multiple sclerosis during relapses and immunomodulatory treatment.

Journal: European journal of neurology 20080401

Title: Fludarabine and mitoxantrone followed by yttrium-90 ibritumomab tiuxetan in previously untreated patients with follicular non-Hodgkin lymphoma trial: a phase II non-randomised trial (FLUMIZ).

Journal: The Lancet. Oncology 20080401

Title: Therapeutic outcome 3 years after switching of immunomodulatory therapies in patients with relapsing-remitting multiple sclerosis in Argentina.

Journal: European journal of neurology 20080401

Title: Cancer risk and impact of disease-modifying treatments in patients with multiple sclerosis.

Journal: Multiple sclerosis (Houndmills, Basingstoke, England) 20080401

Title: Difficulty of peripheral blood stem cell collection after multiple consolidation therapy in acute myeloid leukemia.

Journal: Journal of clinical and experimental hematopathology : JCEH 20080401

Title: Biweekly docetaxel-containing chemotherapy may be the optimal schedule.

Journal: Anti-cancer drugs 20080401

Title: Randomization reveals unexpected acute leukemias in Southwest Oncology Group prostate cancer trial.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080320

Title: Intravenous mitoxantrone and cyclophosphamide as second-line therapy in multiple sclerosis: an open-label comparative study of efficacy and safety.

Journal: Journal of the neurological sciences 20080315

Title: Acute myelogenous leukemia associated with Ollier disease.

Journal: Pediatric blood & cancer 20080301

Title: Treatment of multiple sclerosis with methylprednisolone and mitoxantrone modulates the expression of CXC chemokine receptors in PBMC.

Journal: Journal of clinical immunology 20080301

Title: Chronic myeloid leukemia associated with mitoxantrone treatment in a patient with MS.

Journal: Multiple sclerosis (Houndmills, Basingstoke, England) 20080301

Title: Therapeutic experience of adult acute myeloid leukemia in a single institution of China and its relationship with chromosome karyotype.

Journal: Leukemia & lymphoma 20080301

Title: Mechanisms responsible for reduced cardiotoxicity of mitoxantrone compared to doxorubicin examined in isolated guinea-pig heart preparations.

Journal: The Journal of veterinary medical science 20080301

Title: Severe bladder contracture leading to cystectomy after intravesical mitoxantrone chemotherapy.

Journal: Anti-cancer drugs 20080301

Title: Rapid screening of antineoplastic candidates for the human organic anion transporter OATP1B3 substrates using fluorescent probes.

Journal: Cancer letters 20080218

Title: WRC-213, an l-methionine-conjugated mitoxantrone derivative, displays anticancer activity with reduced cardiotoxicity and drug resistance: identification of topoisomerase II inhibition and apoptotic machinery in prostate cancers.

Journal: Biochemical pharmacology 20080215

Title: A phase 2 trial of fludarabine and mitoxantrone chemotherapy followed by yttrium-90 ibritumomab tiuxetan for patients with previously untreated, indolent, nonfollicular, non-Hodgkin lymphoma.

Journal: Cancer 20080215

Title: Spectroelectrochemistry of the redox activation of anti-cancer drug mitoxantrone.

Journal: Bioelectrochemistry (Amsterdam, Netherlands) 20080201

Title: Cladribine combined with high doses of arabinoside cytosine, mitoxantrone, and G-CSF (CLAG-M) is a highly effective salvage regimen in patients with refractory and relapsed acute myeloid leukemia of the poor risk: a final report of the Polish Adult Leukemia Group.

Journal: European journal of haematology 20080201

Title: High clinical and molecular response rates with fludarabine, cyclophosphamide and mitoxantrone in previously untreated patients with advanced stage follicular lymphoma.

Journal: Haematologica 20080201

Title: Genotoxic stress-induced expression of p53 and apoptosis in leukemic clam hemocytes with cytoplasmically sequestered p53.

Journal: Cancer research 20080201

Title: ABCG2 expression and side population abundance regulated by a transforming growth factor beta-directed epithelial-mesenchymal transition.

Journal: Cancer research 20080201

Title: Pulmonary complications of novel antineoplastic agents for solid tumors.

Journal: Chest 20080201

Title: Cyclic metabolites: chemical and biological considerations.

Journal: Current drug metabolism 20080201

Title: Mitoxantrone: multiple sclerosis: too many serious adverse effects.

Journal: Prescrire international 20080201

Title: Cardiomyopathy in children with Down syndrome treated for acute myeloid leukemia: a report from the Children's Oncology Group Study POG 9421.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080120

Title: Translocation (2;11)(q37;q23) in therapy-related myelodysplastic syndrome after treatment for acute promyelocytic leukemia.

Journal: Cancer genetics and cytogenetics 20080115

Title: Docetaxel plus prednisone or mitoxantrone plus prednisone for advanced prostate cancer: updated survival in the TAX 327 study.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080110

Title: Mitoxantrone as induction treatment in aggressive relapsing remitting multiple sclerosis: treatment response factors in a 5 year follow-up observational study of 100 consecutive patients.

Journal: Journal of neurology, neurosurgery, and psychiatry 20080101

Title: Brain natriuretic peptide as a marker of cardiac toxicity in patients with multiple sclerosis treated with mitoxantrone.

Journal: Journal of neurology 20080101

Title: Long-term outcome of adjuvant chemotherapy cyclophosphamide, mitoxantrone, and fluorouracil in women with breast cancer.

Journal: Acta oncologica (Stockholm, Sweden) 20080101

Title: Fludarabine, cyclophosphamide, and mitoxantrone as initial therapy of chronic lymphocytic leukemia: high response rate and disease eradication.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20080101

Title: Phase II study of low-grade non-Hodgkin lymphomas with fludarabine and mitoxantrone followed by rituximab consolidation: promising results in marginal zone lymphoma.

Journal: Leukemia & lymphoma 20080101

Title: Benign multiple sclerosis: a distinct clinical entity with therapeutic implications.

Journal: Current topics in microbiology and immunology 20080101

Title: [Cognitive impact of mitoxantrone and methylprednisolone in multiple sclerosis: an open label study].

Journal: Revue neurologique 20080101

Title: Successful rescue of an apocrine gland carcinoma metastatic to the cervical lymph nodes by mitoxantrone coupled with trains of permeabilizing electrical pulses (electrochemotherapy).

Journal: In vivo (Athens, Greece) 20080101

Title: Localized small-bowel infarction caused by Aspergillus during chemotherapy for acute myeloid leukemia: report of a case.

Journal: Surgery today 20080101

Title: Current status of cytotoxic chemotherapy in patients with metastatic prostate cancer.

Journal: Urologic oncology 20080101

Title: Prognostic impact of combined fludarabine, treosulfan and mitoxantrone resistance profile in childhood acute myeloid leukemia.

Journal: Anticancer research 20080101

Title: Substantial activity of mitoxantrone and paclitaxel in a heavily pre-treated metastatic bladder cancer patient.

Journal: The Journal of the Louisiana State Medical Society : official organ of the Louisiana State Medical Society 20080101

Title: Interactions between antitumor drugs and vault RNA.

Journal: Nucleic acids symposium series (2004) 20080101

Title: Increased multidrug resistance-associated protein activity in mononuclear cells of patients with systemic lupus erythematosus.

Journal: Clinical and experimental rheumatology 20080101

Title: Use of fludarabine-containing chemotherapeutic regimen results in durable complete remission of subcutaneous panniculitis-like T-cell lymphoma.

Journal: American journal of clinical dermatology 20080101

Title: High-dose chemotherapy with autologous stem cell rescue in stage IIIB inflammatory breast cancer.

Journal: Anticancer research 20080101

Title: Quantitative online detection of low-concentrated drugs via a SERS microfluidic system.

Journal: Chemphyschem : a European journal of chemical physics and physical chemistry 20071221

Title: Phase II study of sequential chemotherapy with docetaxel-estramustine followed by mitoxantrone-prednisone in patients with advanced hormone-refractory prostate cancer.

Journal: British journal of cancer 20071217

Title: Are prostate-specific antigen changes valid surrogates for survival in hormone-refractory prostate cancer? A meta-analysis is needed!

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20071210

Title: Effect of excipients on breast cancer resistance protein substrate uptake activity.

Journal: Journal of controlled release : official journal of the Controlled Release Society 20071204

Title: Two cases of isolated symptomatic myocarditis induced by all-trans retinoic acid (ATRA).

Journal: Annals of hematology 20071201

Title: Aplidin synergizes with cytosine arabinoside: functional relevance of mitochondria in Aplidin-induced cytotoxicity.

Journal: Leukemia 20071201

Title: In vitro and in vivo pharmacological profile of UFP-512, a novel selective delta-opioid receptor agonist; correlations between desensitization and tolerance.

Journal: British journal of pharmacology 20071201

Title: Integration of 18O labeling and solution isoelectric focusing in a shotgun analysis of mitochondrial proteins.

Journal: Journal of proteome research 20071201

Title: Therapeutic effect of anthracene-based anticancer agent ethonafide in an animal model of multiple sclerosis.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20071201

Title: Targeting of Sp1 transcription factor: a novel therapeutic approach for keloids, an in vitro analysis.

Journal: Experimental dermatology 20071201

Title: The naphthoquinones, vitamin K3 and its structural analogue plumbagin, are substrates of the multidrug resistance linked ATP binding cassette drug transporter ABCG2.

Journal: Molecular cancer therapeutics 20071201

Title: Evidence for dual mode of action of a thiosemicarbazone, NSC73306: a potent substrate of the multidrug resistance linked ABCG2 transporter.

Journal: Molecular cancer therapeutics 20071201

Title: [Nursing care of patients with basic multiple sclerosis therapy: preventing relapses].

Journal: Pflege Zeitschrift 20071201

Title: Improvement of cytotoxic effects induced by mitoxantrone on hormone-refractory metastatic prostate cancer cells by co-targeting epidermal growth factor receptor and hedgehog signaling cascades.

Journal: Growth factors (Chur, Switzerland) 20071201

Title: Synthesis and biological evaluation of novel cytotoxic azanaphthoquinone annelated pyrrolo oximes.

Journal: Bioorganic & medicinal chemistry letters 20071115

Title: Erlotinib (Tarceva, OSI-774) antagonizes ATP-binding cassette subfamily B member 1 and ATP-binding cassette subfamily G member 2-mediated drug resistance.

Journal: Cancer research 20071115

Title: The multidrug transporter ABCG2 (BCRP) is inhibited by plant-derived cannabinoids.

Journal: British journal of pharmacology 20071101

Title: Integrating an evidence-based assessment of benefit and risk in disease-modifying treatment of multiple sclerosis.

Journal: Current medical research and opinion 20071101

Title: Advanced age and high initial WBC influence the outcome of inv(3) (q21q26)/t(3;3) (q21;q26) positive AML.

Journal: Leukemia & lymphoma 20071101

Title: Mitoxantrone treatment in multiple sclerosis: a 5-year clinical and MRI follow-up.

Journal: European journal of neurology 20071101

Title: A contemporary prognostic nomogram for men with hormone-refractory metastatic prostate cancer: a TAX327 study analysis.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20071101

Title: VNCOP-B plus rituximab in the treatment of diffuse large B-cell lymphoma in the elderly.

Journal: Leukemia & lymphoma 20071101

Title: [A short duration treatment with intensive consolidation therapy for patients with acute myelogenous leukemia--13 year experience in a single institute].

Journal: Gan to kagaku ryoho. Cancer & chemotherapy 20071101

Title: [MALT (mucosa-associated lymphoid tissue) lymphoma of the lacrimal gland].

Journal: Journal francais d'ophtalmologie 20071101

Title: Phase I trial of FLAGM with high doses of cytosine arabinoside for relapsed, refractory acute myeloid leukemia: study of the Japan Adult Leukemia Study Group (JALSG).

Journal: International journal of hematology 20071101

Title: Neoadjuvant chemotherapy in locally advanced primary breast cancers: the Nottingham experience.

Journal: European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology 20071001

Title: Fludarabine, mitoxantrone and dexamethasone as first-line treatment for T-cell large granular lymphocyte leukemia.

Journal: Leukemia 20071001

Title: A global drug inhibition pattern for the human ATP-binding cassette transporter breast cancer resistance protein (ABCG2).

Journal: The Journal of pharmacology and experimental therapeutics 20071001

Title: Patterns of care study of breast-conserving therapy in Japan: comparison of the treatment process between 1995 1997 and 1999 2001 surveys.

Journal: Japanese journal of clinical oncology 20071001

Title: Malignant pericardial effusion secondary to ovarian adenocarcinoma: a case report.

Journal: The Journal of reproductive medicine 20071001

Title: Mitoxantrone plus vinorelbine in pretreated patients with metastatic breast cancer.

Journal: Journal of chemotherapy (Florence, Italy) 20071001

Title: Reversal of BCRP-mediated multidrug resistance by stable expression of small interfering RNAs.

Journal: Journal of cellular biochemistry 20070901

Title: Mitoxantrone treatment in patients with early relapsing-remitting multiple sclerosis.

Journal: Multiple sclerosis (Houndmills, Basingstoke, England) 20070901

Title: Phase II study of chemotherapy and stem cell transplantation for adult acute lymphoblastic leukemia or lymphoblastic lymphoma: Japan Clinical Oncology Group Study 9004.

Journal: Cancer science 20070901

Title: [Recent advances in the pathogenesis and immunotherapy of multiple sclerosis].

Journal: Der Nervenarzt 20070901

Title: Prostate-specific antigen and pain surrogacy analysis in metastatic hormone-refractory prostate cancer.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20070901

Title: Roscovitine in B-chronic lymphocytic leukemia cells: high apoptosis-inducing efficacy and synergism with alemtuzumab independent of the patients' pretreatment status.

Journal: Haematologica 20070901

Title: Non-Hodgkin's lymphoma in the elderly. Part 2: treatment of diffuse aggressive lymphomas.

Journal: Oncology (Williston Park, N.Y.) 20070901

Title: [A case of recurrent renal cell carcinoma which recurred after fourth surgical resection and survived for about 2 years by medroxyporgesterone acetate administration].

Journal: Hinyokika kiyo. Acta urologica Japonica 20070901

Title: [A clinical observation of fludarabine-containing regimens in the treatment of low grade non-Hodgkin's lymphoma].

Journal: Zhonghua zhong liu za zhi [Chinese journal of oncology] 20070901

Title: Photochemical internalisation of chemotherapy potentiates killing of multidrug-resistant breast and bladder cancer cells.

Journal: British journal of cancer 20070820

Title: Pharmacokinetics and pharmacodynamics of the interferon-betas, glatiramer acetate, and mitoxantrone in multiple sclerosis.

Journal: Journal of the neurological sciences 20070815

Title: Repetitive cycles of high-dose cytarabine are effective for childhood acute myeloid leukemia: long-term outcome of the children with AML treated on two consecutive trials of Tokyo Children's Cancer Study Group.

Journal: Pediatric blood & cancer 20070801

Title: Re: Fabio Calabrò and Cora N. Sternberg. Current indications for chemotherapy in prostate cancer patients. Eur urol 2007;51:17-26.

Journal: European urology 20070801

Title: Paraneoplastic Sweet's syndrome and the pathergy phenomenon.

Journal: Annals of hematology 20070801

Title: Toxicity and outcomes associated with surgical cytoreduction and hyperthermic intraperitoneal chemotherapy (HIPEC) for patients with sarcomatosis.

Journal: Annals of surgical oncology 20070801

Title: On the origin of the decrease in stability of the DNA hairpin d(GCGAAGC) on complexation with aromatic drugs.

Journal: Biophysical chemistry 20070801

Title: Prolonged survival in poor-risk diffuse large B-cell lymphoma following front-line treatment with rituximab-supplemented, early-intensified chemotherapy with multiple autologous hematopoietic stem cell support: a multicenter study by GITIL (Gruppo Italiano Terapie Innovative nei Linfomi).

Journal: Leukemia 20070801

Title: Activity of second-line chemotherapy in docetaxel-refractory hormone-refractory prostate cancer patients : randomized phase 2 study of ixabepilone or mitoxantrone and prednisone.

Journal: Cancer 20070801

Title: Sequential flavopiridol, cytosine arabinoside, and mitoxantrone: a phase II trial in adults with poor-risk acute myelogenous leukemia.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20070801

Title: Successful treatment for recurrence of primary cutaneous anaplastic large-cell lymphoma in elderly patient with etoposide, mitoxantrone, cyclophosphamide, vincristine, prednisolone and bleomycin (VNCOP-B) therapy.

Journal: The Journal of dermatology 20070801

Title: Hyperforin inhibits P-gp and BCRP activities in chronic lymphocytic leukaemia cells and myeloid cells.

Journal: Leukemia & lymphoma 20070801

Title: Leukaemia due to mitoxantrone.

Journal: Prescrire international 20070801

Title: Requirement of Apaf-1 for mitochondrial events and the cleavage or activation of all procaspases during genotoxic stress-induced apoptosis.

Journal: The Biochemical journal 20070701

Title: Expression of the ATP-binding cassette membrane transporter, ABCG2, in human and rodent brain microvessel endothelial and glial cell culture systems.

Journal: Pharmaceutical research 20070701

Title: The effect of short-term intensive chemotherapy on reactivation of tuberculosis.

Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20070701

Title: High anti-lymphoma activity of bendamustine/mitoxantrone/rituximab in rituximab pretreated relapsed or refractory indolent lymphomas and mantle cell lymphomas. A multicenter phase II study of the German Low Grade Lymphoma Study Group (GLSG).

Journal: Leukemia & lymphoma 20070701

Title: Salvage immuno-chemotherapy with a combination of rituximab, high-dose cytarabine, mitoxantrone and dexamethasone for patients with primary CNS lymphoma: a preliminary study.

Journal: Leukemia & lymphoma 20070701

Title: [Mitoxantrone for the treatment of Japanese patients with multiple sclerosis].

Journal: Rinsho shinkeigaku = Clinical neurology 20070701

Title: [Prostate cancer and chemotherapy].

Journal: Bulletin du cancer 20070701

Title: Therapy-related acute nonlymphoblastic leukemia following mitoxantrone therapy in a patient with multiple sclerosis.

Journal: Journal of the Mississippi State Medical Association 20070701

Title: C421 allele-specific ABCG2 gene amplification confers resistance to the antitumor triazoloacridone C-1305 in human lung cancer cells.

Journal: Biochemical pharmacology 20070630

Title: Effect of a single nucleotide polymorphism in the murine double minute 2 promoter (SNP309) on the sensitivity to topoisomerase II-targeting drugs.

Journal: Cancer research 20070615

Title: Pixantrone (BBR 2778) has reduced cardiotoxic potential in mice pretreated with doxorubicin: comparative studies against doxorubicin and mitoxantrone.

Journal: Investigational new drugs 20070601

Title: Ethonafide-induced cytotoxicity is mediated by topoisomerase II inhibition in prostate cancer cells.

Journal: The Journal of pharmacology and experimental therapeutics 20070601

Title: Gemtuzumab ozogamicin with cytarabine and mitoxantrone as a third-line treatment in a poor prognosis group of adult acute myeloid leukemia patients: a single-center experience.

Journal: Annals of hematology 20070601

Title: The quality of molecular response to chemotherapy is predictive for the outcome of AML1-ETO-positive AML and is independent of pretreatment risk factors.

Journal: Leukemia 20070601

Title: Compared benefit of approved and experimental immunosuppressive therapeutic approaches in multiple sclerosis.

Journal: Expert opinion on pharmacotherapy 20070601

Title: Clinical follow-up of 304 patients with multiple sclerosis three years after mitoxantrone treatment.

Journal: Multiple sclerosis (Houndmills, Basingstoke, England) 20070601

Title: Multiple sclerosis in Pakistan.

Journal: Multiple sclerosis (Houndmills, Basingstoke, England) 20070601

Title: Combination therapy for the treatment of multiple sclerosis: challenges and opportunities.

Journal: Current medical research and opinion 20070601

Title: Cladribine combined with cyclophosphamide and mitoxantrone is an active salvage therapy in advanced non-Hodgkin's lymphoma.

Journal: Leukemia & lymphoma 20070601

Title: Energy transfer to analyse membrane-integrated mitoxantrone in BCRP-overexpressed cells.

Journal: Journal of photochemistry and photobiology. B, Biology 20070525

Title: [Advances in the treatment of multiple sclerosis?].

Journal: MMW Fortschritte der Medizin 20070521

Title: Rituximab added to first-line mitoxantrone, chlorambucil, and prednisolone chemotherapy followed by interferon maintenance prolongs survival in patients with advanced follicular lymphoma: an East German Study Group Hematology and Oncology Study.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20070520

Title: Distinct effector cytokine profiles of memory and naive human B cell subsets and implication in multiple sclerosis.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20070515

Title: Mitoxantrone for multiple sclerosis causing acute lymphoblastic leukemia.

Journal: Neurology 20070508

Title: The first case of mitoxantrone exposure in early pregnancy.

Journal: Neurotoxicology 20070501

Title: Silibinin synergizes with mitoxantrone to inhibit cell growth and induce apoptosis in human prostate cancer cells.

Journal: International journal of cancer 20070501

Title: Differential subcellular distribution of mitoxantrone in relation to chemosensitization in two human breast cancer cell lines.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20070501

Title: Divergent cytotoxic effects of PKC412 in combination with conventional antileukemic agents in FLT3 mutation-positive versus -negative leukemia cell lines.

Journal: Leukemia 20070501

Title: Evaluation of relative DNA binding affinities of anthrapyrazoles by electrospray ionization mass spectrometry.

Journal: Journal of mass spectrometry : JMS 20070501

Title: Influence of cladribine alone and in combination with cyclophosphamide or cyclophosphamide and mitoxantrone on bone marrow angiogenesis in chronic lymphocytic leukemia.

Journal: Leukemia & lymphoma 20070501

Title: Monitoring of minimal residual disease in adult acute myeloid leukemia using peripheral blood as an alternative source to bone marrow.

Journal: Haematologica 20070501

Title: Cellular FLICE-inhibitory protein regulates chemotherapy-induced apoptosis in breast cancer cells.

Journal: Molecular cancer therapeutics 20070501

Title: The first 2 years of clinical experience with peripheral blood stem cell transplantation for various hematological malignancies: results from a single Baskent University Center.

Journal: Transplantation proceedings 20070501

Title: A novel substrate mimetic inhibitor of PKB/Akt inhibits prostate cancer tumor growth in mice by blocking the PKB pathway.

Journal: Biochemistry 20070424

Title: Acridone derivatives: design, synthesis, and inhibition of breast cancer resistance protein ABCG2.

Journal: Bioorganic & medicinal chemistry 20070415

Title: Imatinib combined with mitoxantrone/etoposide and cytarabine is an effective induction therapy for patients with chronic myeloid leukemia in myeloid blast crisis.

Journal: Cancer 20070415

Title: Identification of cancer stem cell-like side population cells in human nasopharyngeal carcinoma cell line.

Journal: Cancer research 20070415

Title: Independent regulation of apical and basolateral drug transporter expression and function in placental trophoblasts by cytokines, steroids, and growth factors.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20070401

Title: MEK-ERK is involved in SUMO-1 foci formation on apoptosis.

Journal: Cancer science 20070401

Title: QT prolongation and Torsades de Pointes in patients previously treated with anthracyclines.

Journal: Anti-cancer drugs 20070401

Title: [Preparation of liposome entrapped vincristine sulfate and mitoxantrone chlorhydric acid].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20070401

Title: Improved outcome in childhood acute myeloid leukemia in Singapore with the MRC AML 10 protocol.

Journal: Pediatric blood & cancer 20070301

Title: Evaluation of the myocardial performance index for early detection of mitoxantrone-induced cardiotoxicity in patients with multiple sclerosis.

Journal: European journal of echocardiography : the journal of the Working Group on Echocardiography of the European Society of Cardiology 20070301

Title: Outcome of patients with acute promyelocytic leukemia failing to front-line treatment with all-trans retinoic acid and anthracycline-based chemotherapy (PETHEMA protocols LPA96 and LPA99): benefit of an early intervention.

Journal: Leukemia 20070301

Title: Effect of priming with granulocyte-macrophage colony-stimulating factor in younger adults with newly diagnosed acute myeloid leukemia: a trial by the Acute Leukemia French Association (ALFA) Group.

Journal: Leukemia 20070301

Title: Sequence-dependent synergy of the proteasome inhibitor bortezomib and cytarabine in mantle cell lymphoma.

Journal: Leukemia 20070301

Title: Donor lymphocyte infusion for the treatment of leukemia relapse after HLA-mismatched/haploidentical T-cell-replete hematopoietic stem cell transplantation.

Journal: Haematologica 20070301

Title: [Hodgkin lymphoma in Chile: experience of the national adult cancer program].

Journal: Revista medica de Chile 20070301

Title: Imatinib combined with induction or consolidation chemotherapy in patients with de novo Philadelphia chromosome-positive acute lymphoblastic leukemia: results of the GRAAPH-2003 study.

Journal: Blood 20070215

Title: Proteomic analysis of prodigiosin-induced apoptosis in a breast cancer mitoxantrone-resistant (MCF-7 MR) cell line.

Journal: Investigational new drugs 20070201

Title: Modulation of function of three ABC drug transporters, P-glycoprotein (ABCB1), mitoxantrone resistance protein (ABCG2) and multidrug resistance protein 1 (ABCC1) by tetrahydrocurcumin, a major metabolite of curcumin.

Journal: Molecular and cellular biochemistry 20070201

Title: Mitoxantrone-related acute myeloblastic leukaemia in a patient with metastatic hormone-refractory prostate cancer.

Journal: Anti-cancer drugs 20070201

Title: Early mitoxantrone-induced cardiotoxicity in secondary progressive multiple sclerosis.

Journal: Journal of neurology, neurosurgery, and psychiatry 20070201

Title: Phase III trial of concurrent or sequential adjuvant chemoradiotherapy after conservative surgery for early-stage breast cancer: final results of the ARCOSEIN trial.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20070201

Title: 3-methylcrotonyl-CoA carboxylase deficiency and severe multiple sclerosis.

Journal: Pediatric neurology 20070201

Title: [Mandibular chloroma].

Journal: Revue de stomatologie et de chirurgie maxillo-faciale 20070201

Title: Induction of ATM activation, histone H2AX phosphorylation and apoptosis by etoposide: relation to cell cycle phase.

Journal: Cell cycle (Georgetown, Tex.) 20070201

Title: [A case of multiple lung metastases of hepatocellular carcinoma after resection of liver and tumor thrombi in the inferior vena cava responding to chemotherapy using 5-FU, mitoxantrone and CDDP].

Journal: Gan to kagaku ryoho. Cancer & chemotherapy 20070201

Title: [A case of malignant meningioma treated by individual adjuvant chemotherapy based on the mRNA expression of drug-resistance gene].

Journal: Gan to kagaku ryoho. Cancer & chemotherapy 20070201

Title: Use of rituximab in patients with follicular lymphoma.

Journal: Clinical oncology (Royal College of Radiologists (Great Britain)) 20070201

Title: Anthracyclines, mitoxantrone, radiotherapy, and granulocyte colony-stimulating factor: risk factors for leukemia and myelodysplastic syndrome after breast cancer.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20070120

Title: Cutaneous recall phenomenon at the site of previous doxorubicin extravasation after second-line chemotherapy.

Journal: Journal of the National Cancer Institute 20070117

Title: Bioreductive activation of mitoxantrone by NADPH cytochrome P450 reductase. Implications for increasing its ability to inhibit the growth of sensitive and multidrug resistant leukaemia HL60 cells.

Journal: Cancer letters 20070108

Title: Novel tetrahydroisoquinolin-ethyl-phenylamine based multidrug resistance inhibitors with broad-spectrum modulating properties.

Journal: Cancer chemotherapy and pharmacology 20070101

Title: Current indications for chemotherapy in prostate cancer patients.

Journal: European urology 20070101

Title: The effect of low pH on breast cancer resistance protein (ABCG2)-mediated transport of methotrexate, 7-hydroxymethotrexate, methotrexate diglutamate, folic acid, mitoxantrone, topotecan, and resveratrol in in vitro drug transport models.

Journal: Molecular pharmacology 20070101

Title: Phase II study of the irinotecan (CPT-11), mitoxantrone and dexamethasone regimen in elderly patients with relapsed or refractory peripheral T-cell lymphoma.

Journal: Cancer science 20070101

Title: Initial chemotherapy with mitoxantrone, chlorambucil, prednisone impairs the collection of stem cells in patients with indolent lymphomas--results of a randomized comparison by the German Low-Grade Lymphoma Study Group.

Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20070101

Title: Late relapses in acute promyelocytic leukaemia.

Journal: Acta haematologica 20070101

Title: Epithelial-mesenchymal interactions in keloid pathogenesis modulate vascular endothelial growth factor expression and secretion.

Journal: The Journal of pathology 20070101

Title: Mitoxantrone reduced disability in Iranian patients with multiple sclerosis.

Journal: Archives of Iranian medicine 20070101

Title: [Concurrent chemo-radiotherapy for localized refractory non-Hodgkin's lymphoma--report of two cases].

Journal: Gan to kagaku ryoho. Cancer & chemotherapy 20070101

Title: Three-dimensional cellular spheroid formation provides human prostate tumor cells with tissue-like features.

Journal: Anticancer research 20070101

Title: Mitoxantrone permeability in MDCKII cells is influenced by active influx transport.

Journal: Molecular pharmaceutics 20070101

Title: Immunomodulatory treatment of multiple sclerosis in Norway.

Journal: Acta neurologica Scandinavica. Supplementum 20070101

Title: Response to vinorelbine with or without estramustine as second-line chemotherapy in patients with hormone-refractory prostate cancer.

Journal: Cancer journal (Sudbury, Mass.) 20070101

Title: N-glycan alterations are associated with drug resistance in human hepatocellular carcinoma.

Journal: Molecular cancer 20070101

Title: [Optimization of treatment options through a multidisciplinary approach for advanced hormone refractory prostate carcinoma].

Journal: Tumori 20070101

Title: Curcumin as chemosensitizer.

Journal: Advances in experimental medicine and biology 20070101

Title: Flexible low-intensity combination chemotherapy for elderly patients with acute myeloid leukaemia: a multicentre, phase II study.

Journal: Drugs & aging 20070101

Title: Proteomic analysis to dissect mitoxantrone resistance-associated proteins in a squamous lung carcinoma.

Journal: Anticancer research 20070101

Title: Resistance-associated signatures in breast cancer.

Journal: Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer 20070101

Title: Optical method for real-time monitoring of drug concentrations facilitates the development of novel methods for drug delivery to brain tissue.

Journal: Journal of biomedical optics 20070101

Title: Combined low-dose cytarabine, melphalan and mitoxantrone for older patients with acute myeloid leukemia or high-risk myelodysplastic syndrome.

Journal: Anticancer research 20070101

Title: [The results of a multicenter randomized trial on the treatment of acute myeloid leukemia of adults].

Journal: Terapevticheskii arkhiv 20070101

Title: Therapeutic options for hormone-refractory prostate cancer in 2007.

Journal: Urologic oncology 20070101

Title: Feasibility and efficacy of chemotherapy with gemcitabine mono and with paclitaxel/mitoxantron in gynaecological cancers.

Journal: European journal of gynaecological oncology 20070101

Title: Sensitization against anticancer drugs by transfection with UBE2I variant gene into ras-NIH3H3 mouse fibroblasts.

Journal: Anticancer research 20070101

Title: Docetaxel plus prednisone versus mitoxantrone plus prednisone for metastatic hormone-refractory prostate cancer in Chinese patients: experience of a single center.

Journal: Urologia internationalis 20070101

Title: Utilization, cost trends, and member cost-share for self-injectable multiple sclerosis drugs--pharmacy and medical benefit spending from 2004 through 2007.

Journal: Journal of managed care pharmacy : JMCP 20070101

Title: Valproic acid increases the in vitro effects of nitrosureas on human glioma cell lines.

Journal: Oncology research 20070101

Title: Survival benefit with GM-CSF use after high-dose chemotherapy in high-risk breast cancer.

Journal: Tumori 20070101

Title: Maintenance therapy with rituximab leads to a significant prolongation of response duration after salvage therapy with a combination of rituximab, fludarabine, cyclophosphamide, and mitoxantrone (R-FCM) in patients with recurring and refractory follicular and mantle cell lymphomas: Results of a prospective randomized study of the German Low Grade Lymphoma Study Group (GLSG).

Journal: Blood 20061215

Title: Comment on electron transfer vs differential decay in irradiated DNA.

Journal: The journal of physical chemistry. B 20061214

Title: Evaluation of the antineoplastic activity of mitoxantrone-L-carnitine combination therapy on an experimental solid form of ehrlich tumour in mice.

Journal: Pharmacological research 20061201

Title: Two new cases of acute promyelocytic leukemia following mitoxantrone treatment in patients with multiple sclerosis.

Journal: Leukemia 20061201

Title: In vitro sensitivity of B-cell chronic lymphocytic leukemia to cladribine and its combinations with mafosfamide and/or mitoxantrone.

Journal: Oncology reports 20061201

Title: [Escalating immunomodulatory therapy of multiple sclerosis. Update (September 2006)].

Journal: Der Nervenarzt 20061201

Title: Rituximab induces effective clearance of minimal residual disease in molecular relapses of mantle cell lymphoma.

Journal: Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20061201

Title: Long-term follow-up of autologous peripheral blood stem cell transplantation in the treatment of a patient with acute panmyelosis with myelofibrosis.

Journal: Haematologica 20061201

Title: [Superior sagittal sinus thrombosis during remission induction therapy for acute lymphoblastic leukemia].

Journal: [Rinsho ketsueki] The Japanese journal of clinical hematology 20061201

Title: Treatment of malignant gliomas with mitoxantrone-loaded poly (lactide-co-glycolide) microspheres.

Journal: Neurosurgery 20061201

Title: [Release profile of compound liposomes entrapped with vincristine sulfate and mitoxantrone chlorhydric acid in vitro and their distribution in mice].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20061201

Title: [Long-term application of the multiple sclerosis functional composite test in Debrecen, Hungary].

Journal: Ideggyogyaszati szemle 20061120

Title: Multiple drugbinding sites on the R482G isoform of the ABCG2 transporter.

Journal: British journal of pharmacology 20061101

Title: Cooperative effect of gefitinib and fumitremorgin c on cell growth and chemosensitivity in estrogen receptor alpha negative fulvestrant-resistant MCF-7 cells.

Journal: International journal of oncology 20061101

Title: Microtransponders, the miniature RFID electronic chips, as platforms for cell growth in cytotoxicity assays.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20061101

Title: Inhibition by mitoxantrone of in vitro migration of immunocompetent cells: a possible mechanism for therapeutic efficacy in the treatment of multiple sclerosis.

Journal: Archives of neurology 20061101

Title: [Preparation of mitoxantrone liposomes and study on its in vivo distribution in rats after transdermal delivery].

Journal: Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20061101

Title: Fludarabine, cytarabine, and mitoxantrone (FLAM) for the treatment of relapsed and refractory adult acute lymphoblastic leukemia. A phase study by the Polish Adult Leukemia Group (PALG).

Journal: Annals of hematology 20061001

Title: Inhibition of efflux transporter ABCG2/BCRP does not restore mitoxantrone sensitivity in irinotecan-selected human leukemia CPT-K5 cells: evidence for multifactorial multidrug resistance.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20061001

Title: Non-infusional vs intravenous consolidation chemotherapy in elderly patients with acute myeloid leukemia: final results of the EORTC-GIMEMA AML-13 randomized phase III trial.

Journal: Leukemia 20061001

Title: Less toxicity by optimizing chemotherapy, but not by addition of granulocyte colony-stimulating factor in children and adolescents with acute myeloid leukemia: results of AML-BFM 98.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20060920

Title: Cyclosporin A, tacrolimus and sirolimus are potent inhibitors of the human breast cancer resistance protein (ABCG2) and reverse resistance to mitoxantrone and topotecan.

Journal: Cancer chemotherapy and pharmacology 20060901

Title: Phase II study of the CPT-11, mitoxantrone and dexamethasone regimen in combination with rituximab in elderly patients with relapsed diffuse large B-cell lymphoma.

Journal: Cancer science 20060901

Title: Combined cyclophosphamide, vincristine, doxorubicin, and prednisone (CHOP) improves response rates but not survival and has lower hematologic toxicity compared with combined mitoxantrone, chlorambucil, and prednisone (MCP) in follicular and mantle cell lymphomas: results of a prospective randomized trial of the German Low-Grade Lymphoma Study Group.

Journal: Cancer 20060901

Title: Concurrent administration of adjuvant chemotherapy and radiotherapy after breast-conserving surgery: in regards to Toledano et al. (Int J Radiat Oncol Biol Phys 2006;65:324-332).

Journal: International journal of radiation oncology, biology, physics 20060901

Title: Sequential maintenance treatment with glatiramer acetate after mitoxantrone is safe and can limit exposure to immunosuppression in very active, relapsing remitting multiple sclerosis.

Journal: Journal of neurology 20060901

Title: Fertility in patients with multiple sclerosis: current knowledge and future perspectives.

Journal: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20060901

Title: Anti-cancer activities of 1,4-naphthoquinones: a QSAR study.

Journal: Anti-cancer agents in medicinal chemistry 20060901

Title: A systematic review of the effectiveness of docetaxel and mitoxantrone for the treatment of metastatic hormone-refractory prostate cancer.

Journal: British journal of cancer 20060821

Title: The influence of increasing age on the deliverability and toxicity of fludarabine-based combination chemotherapy regimens in patients with indolent lymphoproliferative disorders.

Journal: Cancer 20060815

Title: Postirradiation electron transfer vs differential radical decay in X-irradiated DNA and its mixtures with additives. Electron spin resonance spectroscopy in LiBr glass at low temperatures.

Journal: The journal of physical chemistry. B 20060803

Title: Mitoxantrone versus cyclophosphamide in secondary-progressive multiple sclerosis: a comparative study.

Journal: Journal of neurology 20060801

Title: Upregulation of secretory connective tissue growth factor (CTGF) in keratinocyte-fibroblast coculture contributes to keloid pathogenesis.

Journal: Journal of cellular physiology 20060801

Title: Activation of ATM and histone H2AX phosphorylation induced by mitoxantrone but not by topotecan is prevented by the antioxidant N-acetyl-L-cysteine.

Journal: Cancer biology & therapy 20060801

Title: Purification of breast cancer resistance protein ABCG2 and role of arginine-482.

Journal: Cellular and molecular life sciences : CMLS 20060801

Title: Combined effect of low-power laser irradiation and anthraquinone anticancer drug aclarubicin on survival of immortalized cells: Comparison with mitoxantrone.

Journal: Cell biology international 20060801

Title: Surgifoam and mitoxantrone in the glioblastoma multiforme postresection cavity: the first step of locoregional chemotherapy through an ad hoc-placed catheter: technical note.

Journal: Neurosurgery 20060801

Title: [Effect of several anti-tumor drugs on apoptosis induction in Jurkat cell line].

Journal: Zhongguo shi yan xue ye xue za zhi 20060801

Title: Modulation of the function of the multidrug resistance-linked ATP-binding cassette transporter ABCG2 by the cancer chemopreventive agent curcumin.

Journal: Molecular cancer therapeutics 20060801

Title: High dose sequential chemotherapy and autologous stem cell transplantation in patients with relapsed/refractory lymphoma.

Journal: Leukemia & lymphoma 20060801

Title: Important differences between topoisomerase-I and -II targeting agents.

Journal: Cancer biology & therapy 20060801

Title: The calcium channel blockers, 1,4-dihydropyridines, are substrates of the multidrug resistance-linked ABC drug transporter, ABCG2.

Journal: Biochemistry 20060725

Title: Complex interaction of BCRP/ABCG2 and imatinib in BCR-ABL-expressing cells: BCRP-mediated resistance to imatinib is attenuated by imatinib-induced reduction of BCRP expression.

Journal: Blood 20060715

Title: Cladribine alone and in combination with cyclophosphamide or cyclophosphamide plus mitoxantrone in the treatment of progressive chronic lymphocytic leukemia: report of a prospective, multicenter, randomized trial of the Polish Adult Leukemia Group (PALG CLL2).

Journal: Blood 20060715

Title: In vitro and in vivo evaluation of WK-X-34, a novel inhibitor of P-glycoprotein and BCRP, using radio imaging techniques.

Journal: International journal of cancer 20060715

Title: Metabolites of ginsenosides as novel BCRP inhibitors.

Journal: Biochemical and biophysical research communications 20060714

Title: Digitoxin, at concentrations commonly found in the plasma of cardiac patients, antagonizes etoposide and idarubicin activity in K562 leukemia cells.

Journal: Leukemia research 20060701

Title: Functional validation of the genetic polymorphisms of human ATP-binding cassette (ABC) transporter ABCG2: identification of alleles that are defective in porphyrin transport.

Journal: Molecular pharmacology 20060701

Title: Study of mitoxantrone for the treatment of recurrent neuromyelitis optica (Devic disease).

Journal: Archives of neurology 20060701

Title: Quality of life and pain in advanced stage prostate cancer: results of a Southwest Oncology Group randomized trial comparing docetaxel and estramustine to mitoxantrone and prednisone.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20060620

Title: Gene expression profiles of two accelerations in a CML patient.

Journal: Leukemia research 20060601

Title: Concurrent administration of adjuvant chemotherapy and radiotherapy after breast-conserving surgery enhances late toxicities: long-term results of the ARCOSEIN multicenter randomized study.

Journal: International journal of radiation oncology, biology, physics 20060601

Title: Phase II study of mitoxantrone and ketoconazole for hormone-refractory prostate cancer.

Journal: Cancer 20060601

Title: CD24 Ala/Val polymorphism and multiple sclerosis.

Journal: Journal of neuroimmunology 20060601

Title: [Concurrent administration of adjuvant chemotherapy and radiotherapy after breast-conservative surgery enhances late toxicities].

Journal: Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique 20060601

Title: Immunological studies of mitoxantrone in primary progressive MS.

Journal: Journal of neuroimmunology 20060601

Title: Myelodysplastic syndrome and acute myeloid leukemia after treatment with fludarabine, mitoxantrone, and dexamethasone.

Journal: American journal of hematology 20060601

Title: Induction of apoptosis and enhancement of chemosensitivity in human prostate cancer LNCaP cells using bispecific antisense oligonucleotide targeting Bcl-2 and Bcl-xL genes.

Journal: BJU international 20060601

Title: Preparation of DHAQ-loaded mPEG-PLGA-mPEG nanoparticles and evaluation of drug release behaviors in vitro/in vivo.

Journal: Journal of materials science. Materials in medicine 20060601

Title: Optimization of preparation of DHAQ-loaded PEG-PLGA-PEG nonaparticles using central composite design.

Journal: Journal of materials science. Materials in medicine 20060601

Title: Double induction containing either two courses or one course of high-dose cytarabine plus mitoxantrone and postremission therapy by either autologous stem-cell transplantation or by prolonged maintenance for acute myeloid leukemia.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20060601

Title: Multidrug resistance and stem cells in acute myeloid leukemia.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20060601

Title: ABCB1 modulation does not circumvent drug extrusion from primitive leukemic progenitor cells and may preferentially target residual normal cells in acute myelogenous leukemia.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20060601

Title: Levocarnitine administration in multiple sclerosis patients with immunosuppressive therapy-induced fatigue.

Journal: Multiple sclerosis (Houndmills, Basingstoke, England) 20060601

Title: Response to second-line chemotherapy in patients with hormone refractory prostate cancer receiving two sequences of mitoxantrone and taxanes.

Journal: Urology 20060601

Title: Current chemotherapeutic approaches for androgen-independent prostate cancer.

Journal: Current opinion in investigational drugs (London, England : 2000) 20060601

Title: The structure of PknB in complex with mitoxantrone, an ATP-competitive inhibitor, suggests a mode of protein kinase regulation in mycobacteria.

Journal: FEBS letters 20060529

Title: Effect of mitoxantrone on MRI in progressive MS: results of the MIMS trial.

Journal: Neurology 20060509

Title: Regulation of BCRP/ABCG2 expression by progesterone and 17beta-estradiol in human placental BeWo cells.

Journal: American journal of physiology. Endocrinology and metabolism 20060501

Title: Targeting cancer cells: magnetic nanoparticles as drug carriers.

Journal: European biophysics journal : EBJ 20060501

Title: Solid lipid nanoparticles of mitoxantrone for local injection against breast cancer and its lymph node metastases.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20060501

Title: Sequential chemotherapy with cisplatin/gemcitabine (CG) followed by mitoxantrone/methotrexate/mitomycin (MMM) in patients with malignant pleural mesothelioma. A multicenter Italian Phase II Study (SITMP1).

Journal: Lung cancer (Amsterdam, Netherlands) 20060501

Title: Rh2 synergistically enhances paclitaxel or mitoxantrone in prostate cancer models.

Journal: The Journal of urology 20060501

Title: The significance of minimal residual disease kinetics in adults with newly diagnosed PML-RARalpha-positive acute promyelocytic leukemia: results of a prospective trial.

Journal: Haematologica 20060501

Title: Changing perspectives of the role of chemotherapy in advanced prostate cancer.

Journal: The Urologic clinics of North America 20060501

Title: [Development of acute type, CD 8 positive adult T-cell leukemia in a carrier of hepatitis B virus--possible therapeutic effect of lamivudine combined with chemotherapy].

Journal: Gan to kagaku ryoho. Cancer & chemotherapy 20060501

Title: [Preparation and characterization of transfersomes of three drugs in vitro].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20060501

Title: Treatment of relapsed acute myeloid leukaemia.

Journal: Reviews on recent clinical trials 20060501

Title: Evaluation of prostate-specific antigen declines for surrogacy in patients treated on SWOG 99-16.

Journal: Journal of the National Cancer Institute 20060419

Title: Multidrug resistance protein 1 (MRP1, ABCC1) mediates resistance to mitoxantrone via glutathione-dependent drug efflux.

Journal: Molecular pharmacology 20060401

Title: Circulating chromogranin a and hormone refractory prostate cancer chemotherapy.

Journal: The Journal of urology 20060401

Title: Chemotherapy for high-risk localized prostate cancer.

Journal: BJU international 20060401

Title: Synthesis and antitumor evaluation of symmetrical 1,5-diamidoanthraquinone derivatives as compared to their disubstituted homologues.

Journal: Chemical & pharmaceutical bulletin 20060401

Title: [Alteration of expression of survivin in HL-60 cells treated with chemotherapeutic drugs].

Journal: Zhongguo shi yan xue ye xue za zhi 20060401

Title: Sensitizing hormone-refractory prostate cancer cells to drug treatment by targeting 14-3-3sigma.

Journal: Molecular cancer therapeutics 20060401

Title: Mitoxantrone-induced cardiotoxicity in patients with multiple sclerosis.

Journal: Archives of Iranian medicine 20060401

Title: [A case of secondary malignant lymphoma of the urinary bladder].

Journal: Hinyokika kiyo. Acta urologica Japonica 20060401

Title: Mitoxantrone, vinblastine and CCNU: long-term follow-up of patients treated for advanced and poor-prognosis Hodgkin's disease.

Journal: Leukemia & lymphoma 20060401

Title: The role of post-remission chemotherapy for older patients with acute myelogenous leukemia.

Journal: Leukemia & lymphoma 20060401

Title: Sequential response-adapted induction and consolidation regimens idarubicin/cytarabine and mitoxantrone/etoposide in adult acute myelogenous leukemia: 10 year follow-up of a study by the Canadian Leukemia Studies Group.

Journal: Leukemia & lymphoma 20060401

Title: Mitoxantrone plus gemcitabine in pretreated patients with metastatic breast cancer.

Journal: Journal of chemotherapy (Florence, Italy) 20060401

Title: Management of worsening multiple sclerosis with mitoxantrone: a review.

Journal: Clinical therapeutics 20060401

Title: Treatment of acute myeloid leukemia in older adults: time to reflect?

Journal: Leukemia & lymphoma 20060401

Title: Inhibition of endosomal sequestration of basic anticancer drugs: influence on cytotoxicity and tissue penetration.

Journal: British journal of cancer 20060327

Title: A phase III trial comparing CHOP to PMitCEBO with or without G-CSF in patients aged 60 plus with aggressive non-Hodgkin's lymphoma.

Journal: British journal of cancer 20060327

Title: PS exposure increases the susceptibility of cells to fusion with DOTAP liposomes.

Journal: Chemico-biological interactions 20060325

Title: A phase III randomized trial comparing adjuvant concomitant chemoradiotherapy versus standard adjuvant chemotherapy followed by radiotherapy in operable node-positive breast cancer: final results.

Journal: International journal of radiation oncology, biology, physics 20060315

Title: Identification of 14-3-3sigma as a contributor to drug resistance in human breast cancer cells using functional proteomic analysis.

Journal: Cancer research 20060315

Title: Long-term follow-up of high-dose mitoxantrone-based induction therapy for patients with newly-diagnosed acute myelogenous leukemia. Twelve year results from a single institution.

Journal: Leukemia & lymphoma 20060301

Title: Treatment for myeloid leukaemia of Down syndrome: population-based experience in the UK and results from the Medical Research Council AML 10 and AML 12 trials.

Journal: British journal of haematology 20060301

Title: First- and second-line chemotherapy with docetaxel or mitoxantrone in patients with hormone-refractory prostate cancer: does sequence matter?

Journal: Cancer 20060301

Title: Positron emission tomography--positive distal femur following fludarabine, dexamethasone and mitoxantrone chemotherapy.

Journal: British journal of haematology 20060301

Title: A high-throughput cell-based assay for inhibitors of ABCG2 activity.

Journal: Journal of biomolecular screening 20060301

Title: The cardiac effects of mitoxantrone: do the benefits in multiple sclerosis outweigh the risks?

Journal: Expert opinion on drug safety 20060301

Title: Mitoxantrone, carboplatin, cytosine arabinoside, and methylprednisolone followed by autologous peripheral blood stem cell transplantation: a salvage regimen for patients with refractory or recurrent non-Hodgkin lymphoma.

Journal: Cancer 20060215

Title: Modulation of p-glycoprotein and breast cancer resistance protein by some prescribed corticosteroids.

Journal: European journal of pharmacology 20060215

Title: Evaluation of carbon dioxide laser ablation combined with mitoxantrone and piroxicam treatment in dogs with transitional cell carcinoma.

Journal: Journal of the American Veterinary Medical Association 20060215

Title: Cell adhesion to fibronectin (CAM-DR) influences acquired mitoxantrone resistance in U937 cells.

Journal: Cancer research 20060215

Title: Relationship between therapeutic efficacy of arterial infusion chemotherapy and expression of P-glycoprotein and p53 protein in advanced hepatocellular carcinoma.

Journal: World journal of gastroenterology 20060214

Title: Continuous infusion intermediate-dose cytarabine, mitoxantrone, plus etoposide for refractory or early relapsed acute myelogenous leukemia.

Journal: Leukemia research 20060201

Title: Randomized Phase II study comparing paclitaxel and carboplatin versus mitoxantrone in patients with hormone-refractory prostate cancer.

Journal: Urology 20060201

Title: [Mitoxantrone in the treatment of multiple sclerosis: risks and benefits].

Journal: Revue neurologique 20060201

Title: [Mitoxantrone as induction therapy in aggressive relapsing remitting multiple sclerosis: a descriptive analysis of 100 consecutive patients].

Journal: Revue neurologique 20060201

Title: [Acute leukaemia in two multiple sclerosis patients treated with mitoxantrone].

Journal: Revue neurologique 20060201

Title: [Investigation on the properties of mitoxantrone-insulin conjugates lyophilized powder].

Journal: Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi 20060201

Title: Doxetaxel: new indication. Prostate cancer: a few more weeks.

Journal: Prescrire international 20060201

Title: [Acute airway obstruction during chemotherapy-induced agranulocytosis with fever].

Journal: Revue de pneumologie clinique 20060201

Title: Mitoxantrone-loaded BSA nanospheres and chitosan nanospheres for local injection against breast cancer and its lymph node metastases. II: Tissue distribution and pharmacodynamics.

Journal: International journal of pharmaceutics 20060113

Title: Mitoxantrone-loaded BSA nanospheres and chitosan nanospheres for local injection against breast cancer and its lymph node metastases. I: Formulation and in vitro characterization.

Journal: International journal of pharmaceutics 20060113

Title: Therapeutic role of mitoxantrone in multiple sclerosis.

Journal: Pharmacology & therapeutics 20060101

Title: Non-Hodgkin disease in beta-thalassemia major.

Journal: American journal of hematology 20060101

Title: Suppression of mitoxantrone cardiotoxicity in multiple sclerosis patients by dexrazoxane.

Journal: Annals of neurology 20060101

Title: Mitoxantrone in multiple sclerosis.

Journal: Advances in neurology 20060101

Title: Multiple sclerosis: advances in understanding, diagnosing, and treating the underlying disease.

Journal: Cleveland Clinic journal of medicine 20060101

Title: Expression and functional activity of breast cancer resistance protein (BCRP, ABCG2) transporter in the human choriocarcinoma cell line BeWo.

Journal: Clinical and experimental pharmacology & physiology 20060101

Title: Transport of glyburide by placental ABC transporters: implications in fetal drug exposure.

Journal: Placenta 20060101

Title: [Tumor cell targetability of folate receptor-mediated mitoxantrone albumin nanoparticles].

Journal: Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20060101

Title: Expression of ABC transporters in human hepatocyte carcinoma cells with cross-resistance to epirubicin and mitoxantrone.

Journal: Anticancer research 20060101

Title: Differential regulation of NF-kappaB activation and function by topoisomerase II inhibitors.

Journal: BMC cancer 20060101

Title: Neoadjuvant mitoxantrone and docetaxel for high-risk localized prostate cancer.

Journal: Urologic oncology 20060101

Title: Early prediction of therapy response in patients with acute myeloid leukemia by nucleosomal DNA fragments.

Journal: BMC cancer 20060101

Title: Skin involvement in Hodgkin's disease.

Journal: Cancer investigation 20060101

Title: Mitoxantrone changes spectrin-aminophospholipid interactions.

Journal: Molecular membrane biology 20060101

Title: The changing pattern of management for hormone-refractory, metastatic prostate cancer.

Journal: Prostate cancer and prostatic diseases 20060101

Title: Gemcitabine plus mitoxantrone and prednisone in the palliative treatment of hormone-resistant prostate cancer (HRPC): A phase II study (GOAM 01.01 study).

Journal: Anticancer research 20060101

Title: Successful management of cerebral and pulmonary mucormycosis with liposomal amphotericin B in a 28-year-old woman with acute lymphoblastic leukemia.

Journal: Acta bio-medica : Atenei Parmensis 20060101

Title: Mitoxantrone-associated acute myelogenous leukemia in a patient with high-risk adenocarcinoma of the prostate: a case report and brief review.

Journal: Cancer investigation 20060101

Title: [Remission in T-cell prolymphocytic leukemia during the FMC treatment course].

Journal: Terapevticheskii arkhiv 20060101

Title: Efficacy of mitoxantrone and intrathecal triamcinolone acetonide treatment in chronic progressive multiple sclerosis patients.

Journal: Clinical neuropharmacology 20060101

Title: In vivo effects of mitoxantrone on the production of pro- and anti-inflammatory cytokines by peripheral blood mononuclear cells of secondary progressive multiple sclerosis patients.

Journal: Neuroimmunomodulation 20060101

Title: Activity of rituximab plus cyclophosphamide, doxorubicin/mitoxantrone, vincristine and prednisone in patients with relapsed MALT lymphoma.

Journal: Oncology 20060101

Title: Mitoxantrone treatment of multiple sclerosis: safety considerations.

Journal: Neurology 20051227

Title: A randomized, postremission comparison of four courses of standard-dose consolidation therapy without maintenance therapy versus three courses of standard-dose consolidation with maintenance therapy in adults with acute myeloid leukemia: the Japan Adult Leukemia Study Group AML 97 Study.

Journal: Cancer 20051215

Title: Results of 58872 and 58921 trials in acute myeloblastic leukemia and relative value of chemotherapy vs allogeneic bone marrow transplantation in first complete remission: the EORTC Children Leukemia Group report.

Journal: Leukemia 20051201

Title: Mechanisms of induction of apoptosis by anthraquinone anticancer drugs aclarubicin and mitoxantrone in comparison with doxorubicin: relation to drug cytotoxicity and caspase-3 activation.

Journal: Apoptosis : an international journal on programmed cell death 20051201

Title: BCRP transports dipyridamole and is inhibited by calcium channel blockers.

Journal: Pharmaceutical research 20051201

Title: [Therapy of hormone-refractory prostate cancer].

Journal: Der Urologe. Ausg. A 20051201

Title: Novel extracellular vesicles mediate an ABCG2-dependent anticancer drug sequestration and resistance.

Journal: Cancer research 20051201

Title: Phase I and pharmacokinetic study of flavopiridol followed by 1-beta-D-arabinofuranosylcytosine and mitoxantrone in relapsed and refractory adult acute leukemias.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20051201

Title: Synergistic interaction between histone deacetylase and topoisomerase II inhibitors is mediated through topoisomerase IIbeta.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20051201

Title: The prognostic value of MLL-AF9 detection in patients with t(9;11)(p22;q23)-positive acute myeloid leukemia.

Journal: Haematologica 20051201

Title: [Preliminary report of fludarabine, mitoxantrone and dexamethasone in treating refractory or relapsed multiple myeloma].

Journal: Ai zheng = Aizheng = Chinese journal of cancer 20051201

Title: Therapeutic options in androgen-independent prostate cancer: building on docetaxel.

Journal: BJU international 20051201

Title: Successful treatment of rhinocerebral zygomycosis with a combination of caspofungin and liposomal amphotericin B.

Journal: Haematologica 20051201

Title: Prediction of doxorubicin sensitivity in breast tumors based on gene expression profiles of drug-resistant cell lines correlates with patient survival.

Journal: Oncogene 20051117

Title: Piperazinobenzopyranones and phenalkylaminobenzopyranones: potent inhibitors of breast cancer resistance protein (ABCG2).

Journal: Journal of medicinal chemistry 20051117

Title: [What was the cause of fever, neck pain and arm paresis? Normal blood picture led to error].

Journal: MMW Fortschritte der Medizin 20051110

Title: Identification of intra- and intermolecular disulfide bridges in the multidrug resistance transporter ABCG2.

Journal: The Journal of biological chemistry 20051104

Title: Multiple sclerosis: Mitoxantrone promotes differential effects on immunocompetent cells in vitro.

Journal: Journal of neuroimmunology 20051101

Title: Assessment of ATM phosphorylation on Ser-1981 induced by DNA topoisomerase I and II inhibitors in relation to Ser-139-histone H2AX phosphorylation, cell cycle phase, and apoptosis.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20051101

Title: Phase II trial of tesmilifene plus mitoxantrone and prednisone for hormone refractory prostate cancer: high subjective and objective response in patients with symptomatic metastases.

Journal: The Journal of urology 20051101

Title: Systemic temozolomide combined with loco-regional mitoxantrone in treating recurrent glioblastoma.

Journal: Journal of neuro-oncology 20051101

Title: Mitoxantrone in the treatment of multiple sclerosis.

Journal: International MS journal 20051101

Title: Mitoxantrone for multiple sclerosis.

Journal: The Cochrane database of systematic reviews 20051019

Title: Severe delayed heart failure in three multiple sclerosis patients previously treated with mitoxantrone.

Journal: Journal of neurology 20051001

Title: Alemtuzumab induced complete remission of therapy-resistant pure red cell aplasia.

Journal: Leukemia research 20051001

Title: Ifosfamide, epirubicin, etoposide (IEV) and autologous peripheral blood progenitor cell transplant: a feasible and effective salvage treatment for lymphoid malignancies.

Journal: Oncology reports 20051001

Title: Rapid collapse of mitochondrial transmembrane potential in HL-60 cells and isolated mitochondria treated with anti-tumor 1,4-anthracenediones.

Journal: Anti-cancer drugs 20051001

Title: Expression level of ABCG2 in the placenta decreases from the mid stage to the end of gestation.

Journal: Bioscience, biotechnology, and biochemistry 20051001

Title: Routine application of the proton-pump inhibitor pantoprazole in patients with gastric lymphoma undergoing chemotherapy.

Journal: Scandinavian journal of gastroenterology 20051001

Title: Effect of mitoxantrone on MRI in progressive MS: results of the MIMS trial.

Journal: Neurology 20050913

Title: A multicenter, open, noncomparative, phase II study of the combination of cladribine (2-chlorodeoxyadenosine), cytarabine, granulocyte colony-stimulating factor and mitoxantrone as induction therapy in refractory acute myeloid leukemia: a report of the Polish Adult Leukemia Group.

Journal: Annals of hematology 20050901

Title: Hetero-association of anticancer antibiotics in aqueous solution: NMR and molecular mechanics analysis.

Journal: Biophysical chemistry 20050901

Title: High-dose mitoxantrone-vinblastine-cyclophosphamide and autologous stem cell transplantation for stage III breast cancer: final results of a prospective multicentre study.

Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20050901

Title: Administration of mylotarg 4 days after beginning of a chemotherapy including intermediate-dose aracytin and mitoxantrone (MIDAM regimen) produces a high rate of complete hematologic remission in patients with CD33+ primary resistant or relapsed acute myeloid leukemia.

Journal: Leukemia research 20050901

Title: Pilot study of tandem high-dose chemotherapy and autologous stem cell transplantation with a novel combination of regimens in patients with poor risk lymphoma.

Journal: Bone marrow transplantation 20050901

Title: Effect of notch ligands on in vitro sensitivity to chemo-therapeutic drugs in leukemia and lymphoma cells.

Journal: Oncology reports 20050901

Title: A prospective randomized study to compare the molecular response rates between central lymphatic irradiation and intensive alternating triple chemotherapy in the treatment of stage I-III follicular lymphoma.

Journal: International journal of radiation oncology, biology, physics 20050901

Title: [Hormone-refractory metastatic prostate carcinoma -- combination improves survival].

Journal: Aktuelle Urologie 20050901

Title: Fludarabine combination therapy is highly effective in first-line and salvage treatment of patients with Waldenström's macroglobulinemia.

Journal: Clinical lymphoma & myeloma 20050901

Title: Prognostic factors and outcome of core binding factor acute myeloid leukemia patients with t(8;21) differ from those of patients with inv(16): a Cancer and Leukemia Group B study.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050820

Title: [Treatment of refractory and relapsed acute lymphocytic leukemia in adults].

Journal: Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences 20050818

Title: Use of MLL/GRAF fusion mRNA for measurement of minimal residual disease during chemotherapy in an infant with acute monoblastic leukemia (AML-M5).

Journal: Genes, chromosomes & cancer 20050801

Title: Interaction of anticancer drug mitoxantrone with DNA analyzed by electrochemical and spectroscopic methods.

Journal: Biophysical chemistry 20050801

Title: Effects of dihydropyridines and pyridines on multidrug resistance mediated by breast cancer resistance protein: in vitro and in vivo studies.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20050801

Title: A longitudinal prospective study of health-related quality of life in breast cancer patients following high-dose chemotherapy with autologous blood stem cell transplantation.

Journal: Bone marrow transplantation 20050801

Title: Gemcitabine and mitoxantrone in metastatic breast cancer: a phase-I-study.

Journal: Investigational new drugs 20050801

Title: Preliminary investigation of mitoxantrone coating on stent-grafts to inhibit neointimal proliferation.

Journal: Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists 20050801

Title: Human splicing factor SPF45 (RBM17) confers broad multidrug resistance to anticancer drugs when overexpressed--a phenotype partially reversed by selective estrogen receptor modulators.

Journal: Cancer research 20050801

Title: The combination of estramustine, vinorelbine, and mitoxantrone in hormone-refractory prostate cancer: a Phase II feasibility study conducted by the Hellenic Cooperative Oncology Group.

Journal: Urology 20050801

Title: [Therapy of hormone refractory prostate cancer: new standards, new trends].

Journal: Aktuelle Urologie 20050801

Title: Weekly docetaxel as second line treatment after mitozantrone for androgen-independent prostate cancer.

Journal: Internal medicine journal 20050801

Title: Multiplicity adjustment for multiple endpoints in clinical trials with multiple doses of an active treatment.

Journal: Statistics in medicine 20050730

Title: [Multiple sclerosis--update].

Journal: Praxis 20050727

Title: Effects of peroxidase substrates on the Amplex red/peroxidase assay: antioxidant properties of anthracyclines.

Journal: Analytical biochemistry 20050715

Title: Immunosuppression and infectious complications in patients with stage IV indolent lymphoma treated with a fludarabine, mitoxantrone, and dexamethasone regimen.

Journal: Cancer 20050715

Title: Characterization of ABCG2 gene amplification manifesting as extrachromosomal DNA in mitoxantrone-selected SF295 human glioblastoma cells.

Journal: Cancer genetics and cytogenetics 20050715

Title: Modulation of breast cancer resistance protein mediated atypical multidrug resistance using RNA interference delivered by adenovirus.

Journal: Chinese medical journal 20050705

Title: [Magnetic Drug Targeting--a new approach in locoregional tumor therapy with chemotherapeutic agents. Experimental animal studies].

Journal: HNO 20050701

Title: [Magnetic drug targeting. New paths for the local concentration of drugs for head and neck cancer].

Journal: HNO 20050701

Title: Transport of anthracyclines and mitoxantrone across membranes by a flip-flop mechanism.

Journal: Biochemical pharmacology 20050701

Title: Use of low-dose mitozantrone to treat aggressive multiple sclerosis: a single-centre open-label study using patient self-assessment and clinical measures of multiple sclerosis status.

Journal: Internal medicine journal 20050701

Title: Prolonging survival in prostate cancer: chemotherapy will have an important role.

Journal: BJU international 20050701

Title: Article on mitoxantrone-induced extravasation raised useful questions.

Journal: Oncology nursing forum 20050701

Title: Autologous or allogeneic stem cell transplantation as post-remission therapy in refractory or relapsed acute myeloid leukemia after highly intensive chemotherapy.

Journal: Leukemia & lymphoma 20050701

Title: Late cardiac toxicity secondary to treatment in Hodgkin's disease. A study comparing doxorubicin, epirubicin and mitoxantrone in combined therapy.

Journal: Leukemia & lymphoma 20050701

Title: Granulocytic sarcoma of the heart: extramedullary relapse of acute myeloblastic leukemia after allogeneic stem cell transplantation successfully treated by chemotherapy alone.

Journal: Leukemia & lymphoma 20050701

Title: Severe toxicity following induction chemotherapy for acute myelogenous leukemia in a patient with Werner's syndrome.

Journal: Leukemia & lymphoma 20050701

Title: Extranodal mantle cell lymphoma in a prolapsed ileostomy stump.

Journal: British journal of haematology 20050701

Title: Reduced intensity conditioning for allograft after cytoreductive autograft in metastatic breast cancer.

Journal: Lancet (London, England) 20050701

Title: Changing the way we think about chronic lymphocytic leukemia.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050620

Title: Phase III randomized multicenter study of a humanized anti-CD33 monoclonal antibody, lintuzumab, in combination with chemotherapy, versus chemotherapy alone in patients with refractory or first-relapsed acute myeloid leukemia.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050620

Title: Promoted electron transfer of mitoxantrone binding with DNA by cytochrome c.

Journal: Biochemical and biophysical research communications 20050617

Title: Myelodysplasia and acute myeloid leukemia following therapy for indolent lymphoma with fludarabine, mitoxantrone, and dexamethasone (FND) plus rituximab and interferon alpha.

Journal: Blood 20050615

Title: Intensive chemotherapy with mitoxantrone administered as a single injection in patients with high-risk acute myeloid leukemia: results of the EMA 2000 trial.

Journal: Annals of hematology 20050601

Title: Short intensive sequential therapy followed by autologous stem cell transplantation in adult Burkitt, Burkitt-like and lymphoblastic lymphoma.

Journal: Leukemia 20050601

Title: [The effect of combined mitoxantrone and methylprednisolone therapy in primary and secondary progressive multiple sclerosis. An applied study in 65 patients].

Journal: Der Nervenarzt 20050601

Title: Impact of three courses of intensified CHOP prior to high-dose sequential therapy followed by autologous stem-cell transplantation as first-line treatment in poor-risk, aggressive non-hodgkin's lymphoma: comparative analysis of Dutch-Belgian Hemato-Oncology Cooperative Group Studies 27 and 40.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050601

Title: High-dose cytarabine and mitoxantrone in consolidation therapy for acute promyelocytic leukemia.

Journal: Leukemia 20050601

Title: High-dose chemotherapy and autologous stem cell rescue for metastatic breast cancer: superior survival for tandem compared with single transplants.

Journal: American journal of clinical oncology 20050601

Title: Flavonoid structure-activity studies identify 6-prenylchrysin and tectochrysin as potent and specific inhibitors of breast cancer resistance protein ABCG2.

Journal: Cancer research 20050601

Title: Preclinical evaluation of gemcitabine combination regimens for application in acute myeloid leukemia.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20050601

Title: The evolving role of chemotherapy in androgen-independent (hormone-refractory) prostate cancer.

Journal: Urology 20050601

Title: Future directions in the treatment of androgen-independent prostate cancer.

Journal: Urology 20050601

Title: An interdisciplinary approach to treating prostate cancer.

Journal: Urology 20050601

Title: High dose sequential chemotherapy with autologous transplantation versus dose-dense chemotherapy MegaCEOP as first line treatment in poor-prognosis diffuse large cell lymphoma: an 'Intergruppo Italiano Linfomi' randomized trial.

Journal: Haematologica 20050601

Title: A pilot trial of combination therapy with mitoxantrone and interferon beta-1b using monthly gadolinium-enhanced magnetic resonance imaging.

Journal: Multiple sclerosis (Houndmills, Basingstoke, England) 20050601

Title: [Structure charateristics of mitoxantrone transforsomes].

Journal: Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi 20050601

Title: Transplant-finalized salvage of adult acute lymphoblastic leukemia: results of a mitoxantrone- and methotrexate-based regimen in 36 patients.

Journal: Leukemia & lymphoma 20050601

Title: Mitoxantrone in secondarily progressive multiple sclerosis: a series of 18 patients.

Journal: Arquivos de neuro-psiquiatria 20050601

Title: Acute myeloid leukaemia induced by mitoxantrone: case report.

Journal: Arquivos de neuro-psiquiatria 20050601

Title: Multicenter randomized phase II study of two schedules of docetaxel, estramustine, and prednisone versus mitoxantrone plus prednisone in patients with metastatic hormone-refractory prostate cancer.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050520

Title: The application of enhanced parallel gatekeeping strategies.

Journal: Statistics in medicine 20050515

Title: Secretory transport of irinotecan metabolite SN-38 across isolated intestinal tissue.

Journal: Cancer chemotherapy and pharmacology 20050501

Title: Update in the management of patients with hormone-refractory prostate cancer.

Journal: Current opinion in urology 20050501

Title: Mitoxantrone as rescue therapy in worsening relapsing-remitting MS patients receiving IFN-beta.

Journal: Journal of neuroimmunology 20050501

Title: Chemotherapy agents and timing of chemotherapy in prostate cancer management.

Journal: Current urology reports 20050501

Title: Immunosuppressive therapy in multiple sclerosis.

Journal: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20050501

Title: The current role of chemotherapy in metastatic hormone-refractory prostate cancer.

Journal: Urology 20050501

Title: Knee arthritis as a rare inaugural manifestation of adult leukemia.

Journal: Rheumatology international 20050501

Title: A practical approach to immunomodulatory therapy for multiple sclerosis.

Journal: Physical medicine and rehabilitation clinics of North America 20050501

Title: [Hormonoresistant metastatic prostate cancer: analysis of two phase III clinical studies].

Journal: Bulletin du cancer 20050501

Title: Immunopathogenesis and immunotherapeutic approaches in multiple sclerosis.

Journal: Expert review of neurotherapeutics 20050501

Title: Impact of TCR status and genotype on outcome in adult T-cell acute lymphoblastic leukemia: a LALA-94 study.

Journal: Blood 20050415

Title: DNA topoisomerase II in therapy-related acute promyelocytic leukemia.

Journal: The New England journal of medicine 20050414

Title: Expression and function of ABCB1 and ABCG2 in human placental tissue.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20050401

Title: Changes in adsorption and permeability of mitoxantrone on plasma membrane of BCRP/MXR resistant cells.

Journal: Biochemical and biophysical research communications 20050401

Title: In vitro assessment of cytotoxic agent combinations for hormone-refractory prostate cancer treatment.

Journal: Anti-cancer drugs 20050401

Title: Effect of Walker A mutation (K86M) on oligomerization and surface targeting of the multidrug resistance transporter ABCG2.

Journal: Journal of cell science 20050401

Title: Multiple bilateral parotid sialoliths in a patient with mucosa-associated lymphoid tissue lymphoma (MALT lymphoma) of the salivary glands.

Journal: Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 20050401

Title: Selective gene silencing of rat ATP-binding cassette G2 transporter in an in vitro blood-brain barrier model by short interfering RNA.

Journal: Journal of neurochemistry 20050401

Title: Molecular basis of the low activity of antitumor anthracenediones, mitoxantrone and ametantrone, in oxygen radical generation catalyzed by NADH dehydrogenase. Enzymatic and molecular modelling studies.

Journal: European journal of medicinal chemistry 20050401

Title: Effects of the mammalian target of rapamycin inhibitor CCI-779 used alone or with chemotherapy on human prostate cancer cells and xenografts.

Journal: Cancer research 20050401

Title: Induction of the ABC-transporters Mdr1/P-gp (Abcb1), mrpl (Abcc1), and bcrp (Abcg2) during establishment of multidrug resistance following exposure to mitoxantrone.

Journal: Journal of chemotherapy (Florence, Italy) 20050401

Title: Intratumoral delivery of mitoxantrone in association with 90-Y radioimmunotherapy (RIT) in recurrent glioblastoma.

Journal: Journal of neuro-oncology 20050401

Title: Which drug combination for hormone-refractory prostate cancer?

Journal: Expert opinion on pharmacotherapy 20050401

Title: Design, synthesis and structure-activity relationships of novel taxane-based multidrug resistance reversal agents.

Journal: Journal of medicinal chemistry 20050324

Title: Cyclosporin A is a broad-spectrum multidrug resistance modulator.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20050315

Title: Breast cancer resistance protein in drug resistance of primitive CD34+38- cells in acute myeloid leukemia.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20050315

Title: Prognostic features for response and survival in elderly patients with de novo acute myeloid leukemia treated with mitoxantrone and intermediate dose cytarabine.

Journal: Leukemia & lymphoma 20050301

Title: Acute myeloid leukemia in the elderly: etoposide when anthracyclins are contraindicated.

Journal: Leukemia & lymphoma 20050301

Title: Combined chemotherapy with carmustine, doxorubicin, etoposide, vincristine, and cyclophosphamide plus mitoxantrone, cytarabine and methotrexate with citrovorum factor for the treatment of aggressive non-Hodgkin lymphoma: a long-term follow-up study.

Journal: Cancer 20050301

Title: Sequential mitoxantrone/prednisone followed by docetaxel/estramustine in patients with hormone refractory metastatic prostate cancer: results of a phase II study.

Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20050301

Title: An open-label pilot study of pentostatin, mitoxantrone, and rituximab in patients with previously untreated, Stage III or IV, low-grade non-Hodgkin lymphoma.

Journal: Cancer 20050301

Title: Long-term follow-up of a randomized trial of fludarabine-mitoxantrone, compared with cyclophosphamide, doxorubicin, vindesine, prednisone (CHVP), as first-line treatment of elderly patients with advanced, low-grade non-Hodgkin's lymphoma before the era of monoclonal antibodies.

Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20050301

Title: Shifting paradigms in prostate cancer; docetaxel plus low-dose prednisone - finally an effective chemotherapy.

Journal: European journal of cancer (Oxford, England : 1990) 20050301

Title: Prediction of individual response to chemotherapy in patients with acute myeloid leukaemia using the chemosensitivity index Ci.

Journal: British journal of haematology 20050301

Title: [Current and new therapeutic strategies in acute myeloid leukemia].

Journal: Gan to kagaku ryoho. Cancer & chemotherapy 20050301

Title: Toxicity of the topoisomerase II inhibitors.

Journal: Expert opinion on drug safety 20050301

Title: [Adams-Stokes attack due to complete atrioventricular block in a patient with acute promyelocytic leukemia during remission induction therapy using all-trans retinoic acid].

Journal: [Rinsho ketsueki] The Japanese journal of clinical hematology 20050301

Title: A phase II trial of continuous infusion of 5-fluorouracil, mitoxantrone, and cisplatin for metastatic hepatocellular carcinoma.

Journal: Cancer 20050215

Title: Gefitinib ('Iressa', ZD1839), an epidermal growth factor receptor tyrosine kinase inhibitor, reverses breast cancer resistance protein/ABCG2-mediated drug resistance.

Journal: Cancer research 20050215

Title: Function-dependent conformational changes of the ABCG2 multidrug transporter modify its interaction with a monoclonal antibody on the cell surface.

Journal: The Journal of biological chemistry 20050211

Title: Topoisomerase II inhibitors, irrespective of their chemical composition, ameliorate experimental arthritis.

Journal: Rheumatology (Oxford, England) 20050201

Title: Perioperative morbidity and quality of life in long-term survivors following cytoreductive surgery and hyperthermic intraperitoneal chemotherapy.

Journal: European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology 20050201

Title: Effective treatment of indolent non-hodgkin's lymphomas with mitoxantrone, chlorambucil and prednisone.

Journal: Onkologie 20050201

Title: Good clinical response of breast cancers to neoadjuvant chemoendocrine therapy is associated with improved overall survival.

Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20050201

Title: The role of mitoxantrone in the treatment of indolent lymphomas.

Journal: The oncologist 20050201

Title: Synergistic antitumor effect of combined use of adenoviral-mediated p53 gene transfer and antisense oligodeoxynucleotide targeting clusterin gene in an androgen-independent human prostate cancer model.

Journal: Molecular cancer therapeutics 20050201

Title: [Chemotherapy for prostate cancer].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20050201

Title: Recent docetaxel studies establish a new standard of care in hormone refractory prostate cancer.

Journal: The Canadian journal of urology 20050201

Title: Does docetaxel plus prednisone prolong the survival of men with metastatic hormone-refractory prostate cancer?

Journal: Nature clinical practice. Oncology 20050201

Title: Can docetaxel plus estramustine prolong survival of men with metastatic hormone-refractory prostate cancer?

Journal: Nature clinical practice. Oncology 20050201

Title: Docetaxel-based regimens, the standard of care for metastatic androgen-insensitive prostate cancer.

Journal: Future oncology (London, England) 20050201

Title: Outcome of induction and postremission therapy in younger adults with acute myeloid leukemia with normal karyotype: a cancer and leukemia group B study.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050120

Title: Up-front tandem high-dose chemotherapy compared with standard chemotherapy with doxorubicin and paclitaxel in metastatic breast cancer: results of a randomized trial.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050120

Title: Cloning and functional analysis of the rhesus macaque ABCG2 gene. Forced expression confers an SP phenotype among hematopoietic stem cell progeny in vivo.

Journal: The Journal of biological chemistry 20050114

Title: Investigation of efflux transport of dehydroepiandrosterone sulfate and mitoxantrone at the mouse blood-brain barrier: a minor role of breast cancer resistance protein.

Journal: The Journal of pharmacology and experimental therapeutics 20050101

Title: Mitoxantrone induces cell death in peripheral blood leucocytes of multiple sclerosis patients.

Journal: Clinical and experimental immunology 20050101

Title: Induction chemotherapy for acute myelogenous leukemia.

Journal: Current hematology reports 20050101

Title: High-dose chemotherapy with haematopoietic stem cell transplantation for metastatic breast cancer patients: final results of the French multicentric randomised CMA/PEGASE 04 protocol.

Journal: European journal of cancer (Oxford, England : 1990) 20050101

Title: A phase I study of estramustine, weekly docetaxel, and carboplatin chemotherapy in patients with hormone-refractory prostate cancer.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20050101

Title: [VNCOP-B (etoposide, mitoxantrone, cyclophosphamide, vincristine, predonisolone, bleomycin) therapy in elderly patients with aggressive non-Hodgkin lymphoma--a study of efficacy and safety, final report].

Journal: Gan to kagaku ryoho. Cancer & chemotherapy 20050101

Title: Complete remissions in chemotherapy of lung cancer models induced in mice by asbestos.

Journal: The Mount Sinai journal of medicine, New York 20050101

Title: Mitoxantrone-induced extravasation.

Journal: Oncology nursing forum 20050101

Title: Separation of liposome-entrapped mitoxantrone from nonliposomal mitoxantrone in plasma: pharmacokinetics in mice.

Journal: Methods in enzymology 20050101

Title: Hypoxia-induced acidification causes mitoxantrone resistance not mediated by drug transporters in human breast cancer cells.

Journal: Cellular oncology : the official journal of the International Society for Cellular Oncology 20050101

Title: Preparation, characterization, and stability of liposome-based formulations of mitoxantrone.

Journal: Drug development and industrial pharmacy 20050101

Title: Acute demyelination: an insight into the effect of mitoxantrone on CNS lesions.

Journal: Journal of neuroradiology. Journal de neuroradiologie 20050101

Title: Modulation of BCRP mediated atypical multidrug resistance phenotype by RNA interference.

Journal: Neoplasma 20050101

Title: Case reports: mitozantrone-induced onycholysis associated with subungual abscesses, paronychia, and pyogenic granuloma.

Journal: Journal of drugs in dermatology : JDD 20050101

Title: Methylxanthines (caffeine, pentoxifylline and theophylline) decrease the mutagenic effect of daunomycin, doxorubicin and mitoxantrone.

Journal: Acta biochimica Polonica 20050101

Title: Mitoxantrone therapy in rapidly worsening multiple sclerosis.

Journal: Bratislavske lekarske listy 20050101

Title: Assessment of potential cardiotoxic side effects of mitoxantrone in patients with multiple sclerosis.

Journal: European neurology 20050101

Title: Prospective randomized study comparing MEMID with a chop-like regimen in elderly patients with aggressive non-Hodgkin's lymphoma.

Journal: Oncology 20050101

Title: Anthracyclines.

Journal: Cancer chemotherapy and biological response modifiers 20050101

Title: Impact of uncertainty on cost-effectiveness analysis of medical strategies: the case of high-dose chemotherapy for breast cancer patients.

Journal: International journal of technology assessment in health care 20050101

Title: Chemotherapy for acute myeloid leukemias with cytosine arabinoside, daunorubicin, etoposide, and mitoxantrone may cause permanent oligoasthenozoospermia or amenorrhea in middle-aged patients.

Journal: Neoplasma 20050101

Title: Acute myeloid leukemia treatment in patients over 60 years of age. Comparison of symptomatic, palliative, and aggressive therapy.

Journal: Neoplasma 20050101

Title: [Chemotherapy of hormone-resistent cancer of the prostate].

Journal: Urologiia (Moscow, Russia : 1999) 20050101

Title: Mechanisms of action for treatments in multiple sclerosis: Does a heterogeneous disease demand a multi-targeted therapeutic approach?

Journal: BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy 20050101

Title: Proteomic evidence for roles for nucleolin and poly[ADP-ribosyl] transferase in drug resistance.

Journal: Journal of proteome research 20050101

Title: [A structural and thermodynamic analysis of novatrone and flavin mononucleotide heteroassociation in aqueous solution by 1H NMR spectroscopy].

Journal: Bioorganicheskaia khimiia 20050101

Title: Celiac axis infusion and microembolization for advanced stage III/IV pancreatic cancer--a phase II study on 265 cases.

Journal: Anticancer research 20050101

Title: Unbiased examination of changes in plasma membrane proteins in drug resistant cancer cells.

Journal: Journal of proteome research 20050101

Title: Soluble form of TRAIL, Fas and FasL in the serum of patients with B-CLL.

Journal: Roczniki Akademii Medycznej w Bialymstoku (1995) 20050101

Title: [Mantle cell lymphoma mimicking chronic lymphocytic leukemia].

Journal: [Rinsho ketsueki] The Japanese journal of clinical hematology 20050101

Title: Mechanism of action of mitoxantrone.

Journal: Neurology 20041228

Title: Review of mitoxantrone in the treatment of multiple sclerosis.

Journal: Neurology 20041228

Title: Mitoxantrone for multiple sclerosis in clinical practice.

Journal: Neurology 20041228

Title: Mitoxantrone treatment of multiple sclerosis: safety considerations.

Journal: Neurology 20041228

Title: Identifying and treating patients with suboptimal responses.

Journal: Neurology 20041228

Title: Use of combination therapy with immunomodulators and immunosuppressants in treating multiple sclerosis.

Journal: Neurology 20041228

Title: Current approved options for treating patients with multiple sclerosis.

Journal: Neurology 20041228

Title: Synthesis and biological evaluation of new 1,5-diazaanthraquinones with cytotoxic activity.

Journal: Bioorganic & medicinal chemistry 20041215

Title: Approval summary: Docetaxel in combination with prednisone for the treatment of androgen-independent hormone-refractory prostate cancer.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20041215

Title: Strategies for managing the side effects of treatments for multiple sclerosis.

Journal: Neurology 20041214

Title: Multidrug transporter activity in lymphocytes.

Journal: British journal of pharmacology 20041201

Title: Breast cancer resistance protein and P-glycoprotein in 149 adult acute myeloid leukemias.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20041201

Title: Radiotherapy is a cost-effective palliative treatment for patients with bone metastasis from prostate cancer.

Journal: International journal of radiation oncology, biology, physics 20041201

Title: Bendamustine/Mitoxantrone/Rituximab (BMR): a very effective, well tolerated outpatient chemoimmunotherapy for relapsed and refractory CD20-positive indolent malignancies. Final results of a pilot study.

Journal: Leukemia & lymphoma 20041201

Title: [Chemotherapy for hepatocellular carcinoma].

Journal: Gan to kagaku ryoho. Cancer & chemotherapy 20041201

Title: Modulation of breast cancer resistance protein (BCRP/ABCG2) gene expression using RNA interference.

Journal: Molecular cancer therapeutics 20041201

Title: [Biodistribution of N-(2-hydroxypropyl) methacrylamide copolymer-bound mitoxantrone in mice bearing Ehrlich solid tumor].

Journal: Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi 20041201

Title: Multiple sclerosis.

Journal: Clinical evidence 20041201

Title: A RasGAP-derived cell permeable peptide potently enhances genotoxin-induced cytotoxicity in tumor cells.

Journal: Oncogene 20041125

Title: Activation of mitochondrial apoptotic pathway in mantle cell lymphoma: high sensitivity to mitoxantrone in cases with functional DNA-damage response genes.

Journal: Oncogene 20041125

Title: [Immunomodulatory therapy in multiple sclerosis].

Journal: Ideggyogyaszati szemle 20041120

Title: The addition of rituximab to a combination of fludarabine, cyclophosphamide, mitoxantrone (FCM) significantly increases the response rate and prolongs survival as compared with FCM alone in patients with relapsed and refractory follicular and mantle cell lymphomas: results of a prospective randomized study of the German Low-Grade Lymphoma Study Group.

Journal: Blood 20041115

Title: Imatinib mesylate (STI571) is a substrate for the breast cancer resistance protein (BCRP)/ABCG2 drug pump.

Journal: Blood 20041101

Title: Incidence and predictors of low chemotherapy dose-intensity in aggressive non-Hodgkin's lymphoma: a nationwide study.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20041101

Title: High dose chemotherapy with thiotepa, mitoxantrone and carboplatin (TMJ) followed by autologous stem cell support in 100 consecutive lymphoma patients in a single centre: analysis of efficacy, toxicity and prognostic factors.

Journal: Leukemia & lymphoma 20041101

Title: Early deaths and treatment-related mortality in children undergoing therapy for acute myeloid leukemia: analysis of the multicenter clinical trials AML-BFM 93 and AML-BFM 98.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20041101

Title: In vitro cytotoxicity of mitoxantrone-incorporated albumin microspheres on acute promyelocytic leukaemia cells.

Journal: Journal of microencapsulation 20041101

Title: Antitumour antibiotic containing regimens for metastatic breast cancer.

Journal: The Cochrane database of systematic reviews 20041018

Title: Docetaxel plus prednisone or mitoxantrone plus prednisone for advanced prostate cancer.

Journal: The New England journal of medicine 20041007

Title: Docetaxel and estramustine compared with mitoxantrone and prednisone for advanced refractory prostate cancer.

Journal: The New England journal of medicine 20041007

Title: Addition of cyclosporin A to the combination of mitoxantrone and etoposide to overcome resistance to chemotherapy in refractory or relapsing acute myeloid leukaemia: a randomised phase II trial from HOVON, the Dutch-Belgian Haemato-Oncology Working Group for adults.

Journal: Leukemia research 20041001

Title: Phase II study of PEND chemotherapy in patients with refractory/relapsed Hodgkin lymphoma.

Journal: Leukemia & lymphoma 20041001

Title: Pharmacoeconomic considerations of multiple sclerosis therapy with the new disease-modifying agents.

Journal: Expert opinion on pharmacotherapy 20041001

Title: [Expression establishment and functional analysis of breast cancer resistance protein with doxycycline induced tet regulating system in mouse fibroblast cell line PA317].

Journal: Ai zheng = Aizheng = Chinese journal of cancer 20041001

Title: Cells resistant to HTI-286 do not overexpress P-glycoprotein but have reduced drug accumulation and a point mutation in alpha-tubulin.

Journal: Molecular cancer therapeutics 20041001

Title: [Pseudomonas sepsis with ecthyma gangrenosum in an acute myeloid leukemia patient].

Journal: [Rinsho ketsueki] The Japanese journal of clinical hematology 20041001

Title: [Clinical study on mitoxantrone contained regimen for treatment of newly diagnosed childhood acute lymphoblastic leukemia].

Journal: Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20041001

Title: Mitochondrial proliferation during apoptosis induced by anticancer agents: effects of doxorubicin and mitoxantrone on cancer and cardiac cells.

Journal: Oncogene 20040916

Title: Is there a role for chemotherapy in prostate cancer?

Journal: British journal of cancer 20040913

Title: Acute promyelocytic leukemia in a patient with multiple sclerosis following treatment with mitoxantrone.

Journal: Leukemia 20040901

Title: The effectiveness and practicality of immunosuppressive drugs.

Journal: International MS journal 20040901

Title: Direct assessment of drug penetration into tissue using a novel application of three-dimensional cell culture.

Journal: Cancer research 20040901

Title: Second-line chemotherapy for hormone-refractory prostate cancer: has the time come?

Journal: Clinical prostate cancer 20040901

Title: [Therapy of painful bone metastases in patients with prostate carcinoma. The AP 32/02 Study of the AUO].

Journal: Der Urologe. Ausg. A 20040901

Title: A nurse-led, patient-centred mitoxantrone service in neurology.

Journal: British journal of nursing (Mark Allen Publishing) 20040901

Title: Mechanisms of mitoxantrone in multiple sclerosis--what is known?

Journal: Journal of the neurological sciences 20040815

Title: Rationale for the use of mitoxantrone in multiple sclerosis.

Journal: Journal of the neurological sciences 20040815

Title: The argument against the use of cyclophosphamide and mitoxantrone in the treatment of multiple sclerosis.

Journal: Journal of the neurological sciences 20040815

Title: Autologous hemopoietic stem cell transplantation in the treatment of multiple sclerosis: rationale and clinical experience.

Journal: Journal of the neurological sciences 20040815

Title: Clinical practice of immunosuppressive treatments in multiple sclerosis: results of a second international questionnaire.

Journal: Journal of the neurological sciences 20040815

Title: Pixantrone (BBR2778): a new immunosuppressant in multiple sclerosis with a low cardiotoxicity.

Journal: Journal of the neurological sciences 20040815

Title: Reversible paraneoplastic neuropathy associated with T-cell large granular lymphocyte leukemia.

Journal: Neurology 20040810

Title: Functional expression of rat ABCG2 on the luminal side of brain capillaries and its enhancement by astrocyte-derived soluble factor(s).

Journal: Journal of neurochemistry 20040801

Title: Sphingosine 1-phosphate receptor agonists attenuate relapsing-remitting experimental autoimmune encephalitis in SJL mice.

Journal: Journal of neuroimmunology 20040801

Title: Predictive parameters of mitoxantrone effectiveness in the treatment of multiple sclerosis.

Journal: Multiple sclerosis (Houndmills, Basingstoke, England) 20040801

Title: Mitoxantrone therapy in multiple sclerosis and acute leukaemia: a case report out of 644 treated patients.

Journal: Multiple sclerosis (Houndmills, Basingstoke, England) 20040801

Title: [Mobilization of peripheral blood stem cells with mitoxantrone and high-dose cytarabine chemotherapy and rhG-CSF in patients with hematopoietic malignancies].

Journal: Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20040801

Title: Surface-enhanced Raman scattering reveals adsorption of mitoxantrone on plasma membrane of living cells.

Journal: Biochemical and biophysical research communications 20040723

Title: Primary adrenal lymphoma presenting as Addison's disease: case report and review of the literature.

Journal: Annals of hematology 20040701

Title: HIV protease inhibitors are inhibitors but not substrates of the human breast cancer resistance protein (BCRP/ABCG2).

Journal: The Journal of pharmacology and experimental therapeutics 20040701

Title: Feasibility and results of autologous stem cell transplantation in de novo acute myeloid leukemia in patients over 60 years old. Results of the CETLAM AML-99 protocol.

Journal: Haematologica 20040701

Title: Randomized Phase II trial of two high-dose chemotherapy regimens with stem cell transplantation for the treatment of advanced ovarian cancer in first remission or chemosensitive relapse: a Southwest Oncology Group study.

Journal: Gynecologic oncology 20040701

Title: [Five cases of de novo acute myeloid leukemia with trilineage myelodysplasia (AML/TMDS) achieved CR with the continuous drip infusion of low-dose etoposide and low-dose cytosine arabinoside combined with mitoxantrone (MEtA)].

Journal: Gan to kagaku ryoho. Cancer & chemotherapy 20040701

Title: IgD kappa myeloma: a new case.

Journal: Joint, bone, spine : revue du rhumatisme 20040701

Title: Combined effects of multiple flavonoids on breast cancer resistance protein (ABCG2)-mediated transport.

Journal: Pharmaceutical research 20040701

Title: Intralesional mitoxantrone biopolymer-mediated chemotherapy prolongs survival in rats with experimental brain tumors.

Journal: Journal of neuro-oncology 20040701

Title: Presentation of extramedullary acute myelogenous leukemia as bilateral testicular masses: response to non-myeloablative allogeneic transplantation.

Journal: Leukemia & lymphoma 20040701

Title: Rh2, a compound extracted from ginseng, hypersensitizes multidrug-resistant tumor cells to chemotherapy.

Journal: Canadian journal of physiology and pharmacology 20040701

Title: Fludarabine and mitoxantrone for patients with chronic lymphocytic leukemia.

Journal: Cancer 20040615

Title: Mitoxantrone resistance in a small cell lung cancer cell line is associated with ABCA2 upregulation.

Journal: British journal of cancer 20040614

Title: A phase II study of timed sequential therapy of acute myelogenous leukemia (AML) for patients over the age of 60: two cycle timed sequential therapy with topotecan, ara-C and mitoxantrone in adults with poor-risk AML.

Journal: Leukemia research 20040601

Title: Treatment of a well differentiated pulmonary adenocarcinoma in a cat by pneumonectomy and adjuvant mitoxantrone chemotherapy.

Journal: Journal of feline medicine and surgery 20040601

Title: Quantification of disseminated tumor cells in the bloodstream of patients with hormone-refractory prostate carcinoma undergoing cytotoxic chemotherapy.

Journal: International journal of oncology 20040601

Title: Pixantrone (BBR2778) reduces the severity of experimental allergic encephalomyelitis.

Journal: Journal of neuroimmunology 20040601

Title: Health outcomes in multiple sclerosis.

Journal: Current opinion in neurology 20040601

Title: Targeting vascular endothelial growth factor for relapsed and refractory adult acute myelogenous leukemias: therapy with sequential 1-beta-d-arabinofuranosylcytosine, mitoxantrone, and bevacizumab.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20040601

Title: Mitoxantrone as a potential therapy for primary progressive multiple sclerosis.

Journal: Multiple sclerosis (Houndmills, Basingstoke, England) 20040601

Title: [Chemotherapy of the hormone-refractory prostate cancer].

Journal: Aktuelle Urologie 20040601

Title: Acute myeloid leukaemia induced by mitoxantrone in a multiple sclerosis patient.

Journal: Journal of neurology 20040601

Title: A modified low-dose regimen of mitoxantrone and prednisolone in patients with androgen-independent prostate cancer.

Journal: Japanese journal of clinical oncology 20040601

Title: Fludarabine, cyclophosphamide and mitoxantrone for untreated follicular lymphoma: a report from the non-Hodgkin's lymphoma co-operative study group.

Journal: Leukemia & lymphoma 20040601

Title: A randomized trial of continuous infusion versus bolus mitoxantrone in combination with cytarabine in newly diagnosed patients with acute myeloblastic leukemia.

Journal: Hematological oncology 20040601

Title: Priming with granulocyte colony-stimulating factor--relation to high-dose cytarabine in acute myeloid leukemia.

Journal: The New England journal of medicine 20040520

Title: Broad-spectrum modulation of ATP-binding cassette transport proteins by the taxane derivatives ortataxel (IDN-5109, BAY 59-8862) and tRA96023.

Journal: Cancer chemotherapy and pharmacology 20040501

Title: The cytoplasmic trafficking of DNA topoisomerase IIalpha correlates with etoposide resistance in human myeloma cells.

Journal: Experimental cell research 20040501

Title: Flavonoids are inhibitors of breast cancer resistance protein (ABCG2)-mediated transport.

Journal: Molecular pharmacology 20040501

Title: Expression, up-regulation, and transport activity of the multidrug-resistance protein Abcg2 at the mouse blood-brain barrier.

Journal: Cancer research 20040501

Title: Heart transplantation in a patient with multiple sclerosis and mitoxantrone-induced cardiomyopathy.

Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20040501

Title: Prognostic impact of early response to induction therapy as assessed by multiparameter flow cytometry in acute myeloid leukemia.

Journal: Haematologica 20040501

Title: Treatment of indolent non-Hodgkin's lymphoma with cladribine as single-agent therapy and in combination with mitoxantrone.

Journal: International journal of hematology 20040501

Title: Bendamustine plus mitoxantrone--a new effective treatment for advanced chronic lymphocytic leukaemia: results of a phase I/II study.

Journal: Leukemia & lymphoma 20040501

Title: Fludarabine, cyclophosphamide and mitoxantrone in relapsed or refractory chronic lymphocytic leukemia and low grade non-Hodgkin's lymphoma.

Journal: Leukemia & lymphoma 20040501

Title: [Selective tumor-accumulation of HPMA copolymer-mitoxantrone conjugates].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20040501

Title: Disease-modifying drugs for the early treatment of multiple sclerosis.

Journal: Expert review of neurotherapeutics 20040501

Title: A molecular understanding of mitoxantrone-DNA adduct formation: effect of cytosine methylation and flanking sequences.

Journal: The Journal of biological chemistry 20040430

Title: Interaction of the breast cancer resistance protein with plant polyphenols.

Journal: Biochemical and biophysical research communications 20040423

Title: Antitumor activity of irofulven monotherapy and in combination with mitoxantrone or docetaxel against human prostate cancer models.

Journal: The Prostate 20040401

Title: Assessment of histone H2AX phosphorylation induced by DNA topoisomerase I and II inhibitors topotecan and mitoxantrone and by the DNA cross-linking agent cisplatin.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20040401

Title: A comparison of the benefits of mitoxantrone and other recent therapeutic approaches in multiple sclerosis.

Journal: Expert opinion on pharmacotherapy 20040401

Title: Rituximab in a patient with acute renal failure due to B-cell lymphomatous infiltration of the kidneys.

Journal: Leukemia & lymphoma 20040401

Title: [Postoperative intraperitioneal hyperthermic chemoperfusion combined with intravenous chemotherapy for 82 advanced gastric cancer patients].

Journal: Zhonghua zhong liu za zhi [Chinese journal of oncology] 20040401

Title: Autologous stem cell transplantation following induction therapy with an anthracycline-based regimen including interferon-alpha for low-grade non-Hodgkin's lymphoma.

Journal: Clinical advances in hematology & oncology : H&O 20040401

Title: Mitoxantrone, etoposide, and cytarabine with or without valspodar in patients with relapsed or refractory acute myeloid leukemia and high-risk myelodysplastic syndrome: a phase III trial (E2995).

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20040315

Title: Determination of the in vivo effects of cladribine alone and its combination with cyclophosphamide or cyclophosphamide and mitoxantrone on Bax and Bcl-2 protein expression in B-CLL cells.

Journal: Oncology reports 20040301

Title: The study of mitoxantrone as a potential immunosuppressor in transgenic pig renal xenotransplantation in baboons: comparison with cyclophosphamide.

Journal: Xenotransplantation 20040301

Title: Fludarabine, mitoxantrone and dexamethasone in the treatment of indolent B- and T-cell lymphoid malignancies in Chinese patients.

Journal: British journal of haematology 20040301

Title: Cumulative incidence and risk factors of mitoxantrone-induced cardiotoxicity in children: a systematic review.

Journal: European journal of cancer (Oxford, England : 1990) 20040301

Title: Combination with liposome-entrapped, ends-modified raf antisense oligonucleotide (LErafAON) improves the anti-tumor efficacies of cisplatin, epirubicin, mitoxantrone, docetaxel and gemcitabine.

Journal: Anti-cancer drugs 20040301

Title: Successful treatment of disseminated nasal T-cell lymphoma using high-dose chemotherapy and autologus peripheral blood stem cell transplantation: a case report.

Journal: Auris, nasus, larynx 20040301

Title: [Primary studies on synthesis and properties of mitoxantrone-insulin conjugates].

Journal: Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20040301

Title: Phase I study of weekly mitoxantrone and docetaxel before prostatectomy in patients with high-risk localized prostate cancer.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20040215

Title: [Multiple sclerosis (MS), an inflammatory or degenerative disease?].

Journal: Presse medicale (Paris, France : 1983) 20040214

Title: [Aggressive multiple sclerosis. Definition and specific therapeutic indication].

Journal: Presse medicale (Paris, France : 1983) 20040214

Title: Differences in the longevity of topo IIalpha and topo IIbeta drug-stabilized cleavable complexes and the relationship to drug sensitivity.

Journal: Cancer chemotherapy and pharmacology 20040201

Title: Marginal effects of regional intra-arterial chemotherapy as an alternative treatment option in advanced pancreatic carcinoma.

Journal: Langenbeck's archives of surgery 20040201

Title: Adjuvant cytotoxic and endocrine therapy in pre- and postmenopausal patients with breast cancer and one to nine infiltrated nodes: five-year results of the Hellenic Cooperative Oncology Group randomized HE 10/92 study.

Journal: American journal of clinical oncology 20040201

Title: Second malignancies after chemotherapy and radiotherapy for Hodgkin disease.

Journal: American journal of clinical oncology 20040201

Title: Gastrointestinal stromal tumours (Br J Surg 2003; 90: 1178-1186).

Journal: The British journal of surgery 20040201

Title: Therapy related acute myeloblastic leukaemia after mitoxantrone treatment in a patient with multiple sclerosis.

Journal: Multiple sclerosis (Houndmills, Basingstoke, England) 20040201

Title: Urinary immunocytology for primary bladder B cell lymphoma.

Journal: Urology 20040201

Title: Granulocyte-macrophage colony-stimulating factor to increase efficacy of mitoxantrone, etoposide and cytarabine in previously untreated elderly patients with acute myeloid leukaemia: a Swedish multicentre randomized trial.

Journal: British journal of haematology 20040201

Title: [Radiation and concomitant chemotherapy after surgery for breast cancer].

Journal: Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique 20040201

Title: Glypican-3 is involved in cellular protection against mitoxantrone in gastric carcinoma cells.

Journal: Oncogene 20040129

Title: Suppressing immunity in advancing MS: too much too late, or too late for much?

Journal: Neurology 20040127

Title: Improved liquid chromatographic method for mitoxantrone quantification in mouse plasma and tissues to study the pharmacokinetics of a liposome entrapped mitoxantrone formulation.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20040105

Title: Infectious complications in pediatric acute myeloid leukemia: analysis of the prospective multi-institutional clinical trial AML-BFM 93.

Journal: Leukemia 20040101

Title: Reversal of breast cancer resistance protein (BCRP/ABCG2)-mediated drug resistance by novobiocin, a coumermycin antibiotic.

Journal: International journal of cancer 20040101

Title: Children with acute myeloblastic leukemia presenting with extramedullary infiltration: the effects of high-dose steroid treatment.

Journal: Leukemia research 20040101

Title: The cardioprotector dexrazoxane augments therapeutic efficacy of mitoxantrone in experimental autoimmune encephalomyelitis.

Journal: Clinical and experimental immunology 20040101

Title: VEPEMB in elderly Hodgkin's lymphoma patients. Results from an Intergruppo Italiano Linfomi (IIL) study.

Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20040101

Title: Treatment of Marburg variant multiple sclerosis with mitoxantrone.

Journal: Journal of neuroimaging : official journal of the American Society of Neuroimaging 20040101

Title: Pleurodesis for malignant pleural effusions.

Journal: The Cochrane database of systematic reviews 20040101

Title: [Antitumor activity of mitoxantrone-nanosphere against murine liver tumor H22].

Journal: Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20040101

Title: Mitoxantrone, vinorelbine and prednisone (MVD) in the treatment of metastatic hormonoresistant prostate cancer--a phase II trial.

Journal: Prostate cancer and prostatic diseases 20040101

Title: Piroxicam, mitoxantrone, and coarse fraction radiotherapy for the treatment of transitional cell carcinoma of the bladder in 10 dogs: a pilot study.

Journal: Journal of the American Animal Hospital Association 20040101

Title: Repeated rituximab maintenance courses in fludarabine-failed young patients with chronic lymphocytic leukaemia responding to FAND chemotherapy.

Journal: The hematology journal : the official journal of the European Haematology Association 20040101

Title: Fludarabine, mitoxantrone and dexamethasone as front-line therapy in elderly patients affected by newly-diagnosed, low-grade non-Hodgkin's lymphomas with unfavorable prognostic factors: results of a phase II study.

Journal: Leukemia & lymphoma 20040101

Title: Mitoxantrone: a review of its use in multiple sclerosis.

Journal: CNS drugs 20040101

Title: Maintenance therapy in childhood acute myeloid leukemia.

Journal: Annals of hematology 20040101

Title: Adjuvant intravesical mitoxantrone versus recombinant interferon-alpha after transurethral resection of superficial bladder cancer: a randomized prospective study.

Journal: Urologia internationalis 20040101

Title: A phase II study of intensive chemotherapy with fludarabine, cytarabine, and mitoxantrone in P glycoprotein-negative high-risk myelodysplastic syndromes.

Journal: The hematology journal : the official journal of the European Haematology Association 20040101

Title: Chemotherapy using 5-fluorouracil, mitoxantrone, and cisplatin for patients with advanced hepatocellular carcinoma: an analysis of 63 cases.

Journal: Journal of gastroenterology 20040101

Title: Formation of mitoxantrone adducts in human tumor cells: potentiation by AN-9 and DNA methylation.

Journal: Oncology research 20040101

Title: Parental longevity and prognosis in elderly patients with aggressive non-Hodgkin's lymphoma.

Journal: Acta oncologica (Stockholm, Sweden) 20040101

Title: Highly altered protein expression profile in the adriamycin resistant MCF-7 cell line.

Journal: Journal of proteome research 20040101

Title: Intravenous immunoglobulin and mitoxantrone stop the progression of secondary progressive multiple sclerosis in a patient with interferon intolerance.

Journal: Revista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993) 20040101

Title: Effective knock down of very high ABCG2 expression by a hammerhead ribozyme.

Journal: Anticancer research 20040101

Title: Paclitaxel and mitoxantrone in metastatic breast cancer: a phase II trial of the Italian Oncology Group for Cancer Research.

Journal: Cancer investigation 20040101

Title: 2-Chlorodeoxyadenosine alone and in combination with cyclophosphamide and mitoxantrone induce apoptosis in B chronic lymphocytic leukemia cells in vivo.

Journal: Cancer detection and prevention 20040101

Title: [Evaluation of the clinical effectivity and toxicity of the FDN regimen (fludarabin, mitoxantron, dexamethason) in patients with follicular lymphoma].

Journal: Casopis lekaru ceskych 20040101

Title: [Evaluation of the long term effect of mitoxantrone on neurological disability in patients with active multiple sclerosis].

Journal: Srpski arhiv za celokupno lekarstvo 20040101

Title: [The multidrug tumor cell resistance phenotype caused by the impaired cell death program].

Journal: Vestnik Rossiiskoi akademii meditsinskikh nauk 20040101

Title: [Use of fludarabin in conjunction with other cytostatics in the treatment of non-Hodgkin lymphoma resistant to standard chemotherapy].

Journal: Voprosy onkologii 20040101

Title: Treatment options in hormone-refractory metastatic prostate carcinoma.

Journal: Tumori 20040101

Title: Mitoxantrone (Novantrone) in multiple sclerosis: new insights.

Journal: Expert review of neurotherapeutics 20040101

Title: 6-Thioguanine, cytarabine, and daunorubicin (TAD) and high-dose cytarabine and mitoxantrone (HAM) for induction, TAD for consolidation, and either prolonged maintenance by reduced monthly TAD or TAD-HAM-TAD and one course of intensive consolidation by sequential HAM in adult patients at all ages with de novo acute myeloid leukemia (AML): a randomized trial of the German AML Cooperative Group.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20031215

Title: Is surgery necessary after complete clinical remission following neoadjuvant chemotherapy for early breast cancer?

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20031215

Title: Reversal of breast cancer resistance protein-mediated drug resistance by tryprostatin A.

Journal: International journal of cancer 20031210

Title: Single amino acid substitutions in the transmembrane domains of breast cancer resistance protein (BCRP) alter cross resistance patterns in transfectants.

Journal: International journal of cancer 20031210

Title: Treatment of extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma) with mitoxantrone, chlorambucil and prednisone (MCP).

Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20031201

Title: Risk and timing of hospitalization for febrile neutropenia in patients receiving CHOP, CHOP-R, or CNOP chemotherapy for intermediate-grade non-Hodgkin lymphoma.

Journal: Cancer 20031201

Title: Secondary acute leukemia following mitoxantrone-based high-dose chemotherapy for primary breast cancer patients.

Journal: Bone marrow transplantation 20031201

Title: Hematopoietic cells from mice that are deficient in both Bcrp1/Abcg2 and Mdr1a/1b develop normally but are sensitized to mitoxantrone.

Journal: BioTechniques 20031201

Title: Chloroma of the orbit in a non-leukemic adult: A case report.

Journal: Orbit (Amsterdam, Netherlands) 20031201

Title: MLL/AF-1p fusion in therapy-related early pre-B acute lymphoblastic leukemia with t(1;11)(p32;q23) translocation developing in the relapse phase of acute promyelocytic leukemia.

Journal: International journal of hematology 20031201

Title: [Acute heart failure in a patient treated by mitoxantrone for multiple sclerosis].

Journal: Revue neurologique 20031201

Title: [Mitoxantrone chemoprophylaxis for multirecurrent multifocal superficial bladder tumours: results of a phase 2 controlled study].

Journal: Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica 20031201

Title: Highlights from the XII European Cancer Conference Copenhagen, Denmark.

Journal: Clinical prostate cancer 20031201

Title: New approach in delivering chemotherapy: locoregional treatment for recurrent glioblastoma (rGBM).

Journal: Journal of experimental & clinical cancer research : CR 20031201

Title: The use of mitoxantrone (Novantrone) for the treatment of multiple sclerosis: report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology.

Journal: Neurology 20031125

Title: Salvage by timed sequential chemotherapy in primary resistant acute myeloid leukemia: analysis of prognostic factors.

Journal: Annals of hematology 20031101

Title: Non-invasive functional and biochemical assessment of mitoxantrone cardiotoxicity in patients with multiple sclerosis.

Journal: Journal of cardiovascular pharmacology 20031101

Title: Pretransplant minimal residual disease level predicts clinical outcome in patients with acute myeloid leukemia receiving high-dose chemotherapy and autologous stem cell transplantation.

Journal: Leukemia 20031101

Title: The role of breast cancer resistance protein in acute lymphoblastic leukemia.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20031101

Title: Synthesis and characterization of the tumor targeting mitoxantrone-insulin conjugate.

Journal: Archives of pharmacal research 20031101

Title: Low L-selectin (CD62L) expression in acute myeloid leukemia correlates with a bad cytogenetic risk.

Journal: European journal of haematology 20031101

Title: Conventional dose fludarabine-based regimens are effective but have excessive toxicity in elderly patients with refractory chronic lymphocytic leukemia.

Journal: Leukemia & lymphoma 20031101

Title: Tumor acidity, ion trapping and chemotherapeutics. II. pH-dependent partition coefficients predict importance of ion trapping on pharmacokinetics of weakly basic chemotherapeutic agents.

Journal: Biochemical pharmacology 20031001

Title: [Mitoxanthrone in the therapy of multiple sclerosis].

Journal: Der Nervenarzt 20031001

Title: Inhibition of induced chemoresistance by cotreatment with (E)-5-(2-bromovinyl)-2'-deoxyuridine (RP101).

Journal: Cancer research 20030915

Title: New and emerging treatment options for multiple sclerosis.

Journal: The Lancet. Neurology 20030901

Title: Randomized, double-blind, controlled trial of mitoxantrone/prednisone and clodronate versus mitoxantrone/prednisone and placebo in patients with hormone-refractory prostate cancer and pain.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20030901

Title: Synergistic effects of chemotherapeutic drugs in lymphoma cells are associated with down-regulation of inhibitor of apoptosis proteins (IAPs), prostate-apoptosis-response-gene 4 (Par-4), death-associated protein (Daxx) and with enforced caspase activation.

Journal: Biochemical pharmacology 20030901

Title: The effect of mitoxantrone on anti-pig immunization in baboons.

Journal: Xenotransplantation 20030901

Title: Wild-type breast cancer resistance protein (BCRP/ABCG2) is a methotrexate polyglutamate transporter.

Journal: Cancer research 20030901

Title: Extramedullary acute myeloid leukemia (granulocytic sarcoma) with arm paresis, maculopapular exanthema and organ involvement.

Journal: Leukemia & lymphoma 20030901

Title: Non-Hodgkin's lymphoma presenting as a giant chest wall mass.

Journal: Leukemia & lymphoma 20030901

Title: Rituximab in heavily pretreated cutaneous B-cell lymphoma.

Journal: Leukemia & lymphoma 20030901

Title: Mitoxantrone-cyclophosphamide-rituximab: an effective and safe combination for indolent NHL.

Journal: Hematological oncology 20030901

Title: Efficacy of mitoxantrone-loaded albumin microspheres for intratumoral chemotherapy of breast cancer.

Journal: Journal of controlled release : official journal of the Controlled Release Society 20030828

Title: Quinine as a multidrug resistance inhibitor: a phase 3 multicentric randomized study in adult de novo acute myelogenous leukemia.

Journal: Blood 20030815

Title: Mitoxantrone and cytarabine induction, high-dose cytarabine, and etoposide intensification for pediatric patients with relapsed or refractory acute myeloid leukemia: Children's Cancer Group Study 2951.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20030801

Title: Risk-adapted postremission therapy in acute myeloid leukemia: results of the German multicenter AML HD93 treatment trial.

Journal: Leukemia 20030801

Title: Expression and functional analyses of breast cancer resistance protein in lung cancer.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20030801

Title: Therapy-related leukemia in mitozantrone treated patients.

Journal: Multiple sclerosis (Houndmills, Basingstoke, England) 20030801

Title: [Newer disease--modifying drugs: glatiramer acetate and mitoxantrone].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20030801

Title: [Immunologic therapy for secondary and primary progressive multiple sclerosis].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20030801

Title: Oxidation of mitoxantrone by lactoperoxidase.

Journal: Biochimica et biophysica acta 20030730

Title: Prognosis of inv(16)/t(16;16) acute myeloid leukemia (AML): a survey of 110 cases from the French AML Intergroup.

Journal: Blood 20030715

Title: Long-term remission in mantle cell lymphoma following high-dose sequential chemotherapy and in vivo rituximab-purged stem cell autografting (R-HDS regimen).

Journal: Blood 20030715

Title: Clinical effects of combination therapy with mitoxantrone, vincristine, and prednisolone in breast cancer.

Journal: Cancer chemotherapy and pharmacology 20030701

Title: Intraperitoneal chemotherapy with mitoxantrone in malignant ascites.

Journal: Surgical oncology clinics of North America 20030701

Title: Chemotherapy of prostate cancer: present and future.

Journal: Current urology reports 20030601

Title: Timed-sequential chemotherapy with concomitant granulocyte colony-stimulating factor for newly diagnosed de novo acute myelogenous leukemia.

Journal: Leukemia 20030601

Title: Bone marrow stromal-derived soluble factors and direct cell contact contribute to de novo drug resistance of myeloma cells by distinct mechanisms.

Journal: Leukemia 20030601

Title: High-dose sequential chemotherapy and peripheral blood progenitor cell autografting in patients with refractory and/or recurrent Hodgkin lymphoma: a multicenter study of the intergruppo Italiano Linfomi showing prolonged disease free survival in patients treated at first recurrence.

Journal: Cancer 20030601

Title: The combination of estramustine and mitoxantrone in hormone-refractory prostate cancer: a phase II feasibility study conducted by the Hellenic Cooperative Oncology Group.

Journal: Urology 20030601

Title: First-line treatment with brief-duration chemotherapy plus rituximab in elderly patients with intermediate-grade non-Hodgkin's lymphoma: phase II trial.

Journal: Clinical lymphoma 20030601

Title: The potential effect of short-course high-dose steroid on the maturation and apoptosis of leukemic cells in a child with acute megakaryoblastic leukemia.

Journal: Leukemia & lymphoma 20030601

Title: Multiple paradigm shifts in multiple sclerosis.

Journal: Current opinion in neurology 20030601

Title: Current disease-modifying therapies in multiple sclerosis.

Journal: Seminars in neurology 20030601

Title: [Diagnosis and treatment of multiple sclerosis. Update, 2003].

Journal: MMW Fortschritte der Medizin 20030526

Title: CHOP is superior to CNOP in elderly patients with aggressive lymphoma while outcome is unaffected by filgrastim treatment: results of a Nordic Lymphoma Group randomized trial.

Journal: Blood 20030515

Title: Combination of fludarabine and mitoxantrone in untreated stages III and IV low-grade lymphoma: S9501.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20030515

Title: Waldenstrom's macroglobulinemia: is there a place and time for a cease-fire?

Journal: Leukemia research 20030501

Title: The effect of loss of Brca1 on the sensitivity to anticancer agents in p53-deficient cells.

Journal: International journal of oncology 20030501

Title: Activity of docetaxel with or without estramustine phosphate versus mitoxantrone in androgen dependent and independent human prostate cancer xenografts.

Journal: The Journal of urology 20030501

Title: Acute myelogenous leukemia following mitoxantrone treatment for multiple sclerosis.

Journal: The Annals of pharmacotherapy 20030501

Title: Randomized multicentric study of perioperative chemotherapy with mitoxantrone in early breast cancer.

Journal: Annals of surgical oncology 20030501

Title: A case of acute promyelocytic leukaemia following mitoxantrone treatment of multiple sclerosis.

Journal: Leukemia 20030501

Title: Electrochemical determination of interaction parameters for DNA and mitoxantrone in an irreversible redox process.

Journal: Biophysical chemistry 20030501

Title: Therapy-related acute myeloblastic leukemia after mitoxantrone treatment in a patient with MS.

Journal: Neurology 20030422

Title: Mitoxantrone and prolonged infusion gemcitabine as salvage therapy in patients with acute myelogenous leukemia.

Journal: Leukemia research 20030401

Title: Relevance of drug uptake, cellular distribution and cell membrane fluidity to the enhanced sensitivity of Down's syndrome fibroblasts to anticancer antibiotic-mitoxantrone.

Journal: Biochimica et biophysica acta 20030401

Title: [Mitoxantrone, a new reality].

Journal: Revista de neurologia 20030401

Title: Partially successful treatment of a patient with chronic lymphocytic leukemia and Hodgkin's disease: case report and literature review.

Journal: American journal of hematology 20030401

Title: Local delivery of mitoxantrone for the treatment of malignant brain tumors in rats.

Journal: Journal of neurosurgery 20030401

Title: [Drug-resistant proteins in breast cancer: recent progress in multidrug resistance].

Journal: Ai zheng = Aizheng = Chinese journal of cancer 20030401

Title: Safety and efficacy of the MDR inhibitor Incel (biricodar, VX-710) in combination with mitoxantrone and prednisone in hormone-refractory prostate cancer.

Journal: Cancer chemotherapy and pharmacology 20030401

Title: A randomized trial comparing intensified CNOP vs. CHOP in patients with aggressive non-Hodgkin's lymphoma.

Journal: Leukemia & lymphoma 20030401

Title: Intrapericardial instillation of mitoxantrone in palliative therapy of malignant pericardial effusion.

Journal: Onkologie 20030401

Title: Magnetic drug targeting--biodistribution of the magnetic carrier and the chemotherapeutic agent mitoxantrone after locoregional cancer treatment.

Journal: Journal of drug targeting 20030401

Title: Mitoxantrone trial in multiple sclerosis.

Journal: Lancet (London, England) 20030329

Title: Investigation on the interaction of DNA and electroactive ligands using a rapid electrochemical method.

Journal: Journal of biochemical and biophysical methods 20030328

Title: A significant diffuse component predicts for inferior survival in grade 3 follicular lymphoma, but cytologic subtypes do not predict survival.

Journal: Blood 20030315

Title: Association of genomic imbalances with drug resistance and thermoresistance in human gastric carcinoma cells.

Journal: International journal of cancer 20030301

Title: [Adjuvant and additive therapy for cancer of the pancreas].

Journal: Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen 20030301

Title: Application of a human multidrug transporter (ABCG2) variant as selectable marker in gene transfer to progenitor cells.

Journal: Human gene therapy 20030301

Title: Therapy-related acute myelogenous leukaemia (t-AML) in a patient with multiple sclerosis treated with mitoxantrone.

Journal: Multiple sclerosis (Houndmills, Basingstoke, England) 20030301

Title: Phase I/II study of gemcitabine plus mitoxantrone as salvage chemotherapy in metastatic breast cancer.

Journal: British journal of cancer 20030224

Title: Synthesis and biological evaluation of 2,7-Dihydro-3H-dibenzo[de,h]cinnoline-3,7-dione derivatives, a novel group of anticancer agents active on a multidrug resistant cell line.

Journal: Bioorganic & medicinal chemistry 20030220

Title: Mitoxantrone in progressive multiple sclerosis: when and how to treat?

Journal: Journal of the neurological sciences 20030215

Title: Interferon beta-1a in primary progressive multiple sclerosis.

Journal: Journal of the neurological sciences 20030215

Title: A randomised multicentre trial of modified CHOP versus MCOP in patients aged 65 years and over with aggressive non-Hodgkin's lymphoma.

Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20030201

Title: Clinical evaluation of mitoxantrone and piroxicam in a canine model of human invasive urinary bladder carcinoma.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20030201

Title: The last to die is hope: prolonged mechanical circulatory support with a Novacor left ventricular assist device as a bridge to transplantation.

Journal: The Journal of thoracic and cardiovascular surgery 20030201

Title: Chemosensitization of human prostate cancer using antisense agents targeting the type 1 insulin-like growth factor receptor.

Journal: BJU international 20030201

Title: Randomized phase III study for the treatment of advanced indolent non-Hodgkin's lymphomas (NHL) and mantle cell lymphoma: chemotherapy versus chemotherapy plus rituximab.

Journal: Annals of hematology 20030201

Title: Rapid onset mitoxantrone-induced cardiotoxicity in secondary progressive multiple sclerosis.

Journal: Multiple sclerosis (Houndmills, Basingstoke, England) 20030201

Title: Severe heart failure in a young multiple sclerosis patient.

Journal: Journal of neurology 20030201

Title: Serial gadolinium-enhanced MRI in acute attack of multiple sclerosis treated with plasma exchange.

Journal: Journal of neurology 20030201

Title: Rituximab plus chemotherapy in follicular and mantle cell lymphomas.

Journal: Seminars in oncology 20030201

Title: A randomized trial comparing intravesical instillations of mitoxantrone and doxorubicin in patients with superficial bladder cancer.

Journal: Chang Gung medical journal 20030201

Title: A cost-utility analysis of mitoxantrone hydrochloride and interferon beta-1b in the treatment of patients with secondary progressive or progressive relapsing multiple sclerosis.

Journal: Clinical therapeutics 20030201

Title: Saccharomyces cerevisiae as an eukaryotic cell model to assess cytotoxicity and genotoxicity of three anticancer anthraquinones.

Journal: Mutagenesis 20030101

Title: Recent advances in pediatric acute lymphoblastic and myeloid leukemia.

Journal: Current opinion in oncology 20030101

Title: Treatment of large cell lymphoma in elderly patients with a mitoxantrone, cyclophosphamide, etoposide, and prednisone regimen: long-term follow-up results.

Journal: Cancer 20030101

Title: NOVP chemotherapy for Hodgkin's disease transiently induces sperm aneuploidies associated with the major clinical aneuploidy syndromes involving chromosomes X, Y, 18, and 21.

Journal: Cancer research 20030101

Title: Reversal of breast cancer resistance protein-mediated drug resistance by estrogen antagonists and agonists.

Journal: Molecular cancer therapeutics 20030101

Title: Treatment of multiple sclerosis and related disorders: what's new in the past 2 years?

Journal: Clinical neuropharmacology 20030101

Title: Multiple sclerosis. Treatment is shifting.

Journal: Mayo Clinic health letter (English ed.) 20030101

Title: Effects of mitoxantrone on multiple sclerosis patients' lymphocyte subpopulations and production of immunoglobulin, TNF-alpha and IL-10.

Journal: European neurology 20030101

Title: A phase I-II study of rituximab, ifosfamide, mitoxantrone and etoposide (R-IME) for B cell non-Hodgkin's lymphoma prior to and after high-dose chemotherapy and autologous stem cell transplantation (HDC-ASCT).

Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20030101

Title: Rituximab in combination with CNOP chemotherapy in patients with previously untreated indolent non-Hodgkin's lymphoma.

Journal: The hematology journal : the official journal of the European Haematology Association 20030101

Title: [Analysis of causes of death during intensive chemotherapy according to treatment protocol AML-BFM 93].

Journal: Klinische Padiatrie 20030101

Title: High-risk localized prostate cancer: primary surgery and adjuvant therapy.

Journal: Urologic oncology 20030101

Title: Regional celiac artery infusion in the adjuvant treatment of pancreatic cancer.

Journal: Anticancer research 20030101

Title: [Mitoxantrone].

Journal: Neurologia (Barcelona, Spain) 20030101

Title: New principles in the treatment of prostate cancer--the oncologist's view.

Journal: Scandinavian journal of urology and nephrology. Supplementum 20030101

Title: Mitoxantrone mediates demethylation and reexpression of cyclin d2, estrogen receptor and 14.3.3sigma in breast cancer cells.

Journal: Cancer biology & therapy 20030101

Title: Mitoxantrone: a hypomethylating agent?

Journal: Cancer biology & therapy 20030101

Title: Novobiocin sensitizes BCRP/MXR/ABCP overexpressing topotecan-resistant human breast carcinoma cells to topotecan and mitoxantrone.

Journal: Anticancer research 20030101

Title: DNA damage induced by DNA topoisomerase I- and topoisomerase II-inhibitors detected by histone H2AX phosphorylation in relation to the cell cycle phase and apoptosis.

Journal: Cell cycle (Georgetown, Tex.) 20030101

Title: First-line intra-arterial chemotherapy (IAC) with epirubicin and mitoxantrone in locally advanced breast cancer.

Journal: Anticancer research 20030101

Title: The interaction of daunorubicin and mitoxantrone with the red blood cells of acute myeloid leukemia patients.

Journal: Cellular & molecular biology letters 20030101

Title: Immunosuppressive antimetabolites inhibit induction of contact hypersensitivity while lymphoablative drugs also prevent its expression.

Journal: European journal of dermatology : EJD 20030101

Title: High-dose chemotherapy with mitoxantrone + melphalan and autologous stem cell rescue in metastatic breast cancer patients: a study of feasibility and tolerability.

Journal: Tumori 20030101

Title: Fludarabine, mitoxantrone, dexamethasone (FND) compared with an alternating triple therapy (ATT) regimen in patients with stage IV indolent lymphoma.

Journal: Blood 20021215

Title: Low levels of ABCG2 expression in adult AML blast samples.

Journal: Blood 20021215

Title: Characterization of drug transport, ATP hydrolysis, and nucleotide trapping by the human ABCG2 multidrug transporter. Modulation of substrate specificity by a point mutation.

Journal: The Journal of biological chemistry 20021213

Title: ABCG2 confers resistance to indolocarbazole compounds by ATP-dependent transport.

Journal: Biochemical and biophysical research communications 20021213

Title: Outcome after induction chemotherapy for older patients with acute myeloid leukemia is not improved with mitoxantrone and etoposide compared to cytarabine and daunorubicin: a Southwest Oncology Group study.

Journal: Blood 20021201

Title: Phase III study of mitoxantrone plus low dose prednisone versus low dose prednisone alone in patients with asymptomatic hormone refractory prostate cancer.

Journal: The Journal of urology 20021201

Title: Editorial: States and state transitions are all that really matter.

Journal: The Journal of urology 20021201

Title: Issues and practices in multiple sclerosis.

Journal: Neurorehabilitation and neural repair 20021201

Title: Fludarabine, cyclophosphamide and mitoxantrone in the treatment of resistant or relapsed chronic lymphocytic leukaemia.

Journal: British journal of haematology 20021201

Title: Favorable outcome with STI571 (imatinib mesylate) and allogeneic stem cell transplantation in a case of Ph+ chemorefractory acute lymphocytic leukaemia.

Journal: Bone marrow transplantation 20021201

Title: Adjuvant intraperitoneal chemotherapy with cisplatinum, mitoxantrone, 5-fluorouracil, and calcium folinate in patients with gastric cancer: a phase II study.

Journal: American journal of clinical oncology 20021201

Title: [Immunosuppressive medication in multiple sclerosis].

Journal: Revista de neurologia 20021201

Title: Mitoxantrone in progressive multiple sclerosis: a placebo-controlled, double-blind, randomised, multicentre trial.

Journal: Lancet (London, England) 20021201

Title: Alternation of epirubicin and mitoxantrone in CHOP-like regimens retains efficacy and reduces overall toxicity in elderly patients with high and intermediate grade non-Hodgkin lymphomas.

Journal: Leukemia & lymphoma 20021201

Title: Prevention of autoimmune attack and disease progression in multiple sclerosis: current therapies and future prospects.

Journal: Internal medicine journal 20021101

Title: Is first-line single-agent mitoxantrone in the treatment of high-risk metastatic breast cancer patients as effective as combination chemotherapy? No difference in survival but higher quality of life were found in a multicenter randomized trial.

Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20021101

Title: Blast crisis of chronic myeloid leukemia: diagnosis prompted by T(8;9).

Journal: Journal of pediatric hematology/oncology 20021101

Title: Local delivery of mitoxantrone for the treatment of malignant brain tumors in rats.

Journal: Journal of neurosurgery 20021101

Title: Treatment of secondary myelodysplastic syndrome after heart transplantation with chemotherapy and nonmyeloablative stem-cell transplantation.

Journal: Transplantation 20021027

Title: [Increased response rate with rituximab in relapsed and refractory follicular and mantle cell lymphomas -- results of a prospective randomized study of the German Low-Grade Lymphoma Study Group].

Journal: Deutsche medizinische Wochenschrift (1946) 20021025

Title: Inhibition of basal and transforming growth factor-beta-induced stimulation of COL1A1 transcription by the DNA intercalators, mitoxantrone and WP631, in cultured human dermal fibroblasts.

Journal: The Journal of biological chemistry 20021011

Title: Visual recovery in a man with the rare combination of mtDNA 11778 LHON mutation and a MS-like disease after mitoxantrone therapy.

Journal: Acta neurologica Scandinavica 20021001

Title: Outcome of treatment in adults with Philadelphia chromosome-positive acute lymphoblastic leukemia--results of the prospective multicenter LALA-94 trial.

Journal: Blood 20021001

Title: Treatment of hemophagocytic lymphohistiocytosis with HLH-94 immunochemotherapy and bone marrow transplantation.

Journal: Blood 20021001

Title: Efficacy and tolerance of a scalp-cooling system for prevention of hair loss and the experience of breast cancer patients treated by adjuvant chemotherapy.

Journal: Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 20021001

Title: A study of therapy-related acute leukaemia after mitoxantrone therapy for multiple sclerosis.

Journal: Multiple sclerosis (Houndmills, Basingstoke, England) 20021001

Title: CMF (cyclophosphamide, methotrexate, 5-fluorouracil) versus CNF (cyclophosphamide, mitoxantrone, 5-fluorouracil) as adjuvant chemotherapy for stage II lymph-node positive breast cancer: results by demographic and clinical subgroups.

Journal: American journal of clinical oncology 20021001

Title: Correlation of p53 immunostaining in primary and residual ovarian cancer at the time of positive second-look laparotomy and its prognostic role: a Southwest Oncology Group ancillary study.

Journal: Gynecologic oncology 20021001

Title: Cardiac adverse effects associated with mitoxantrone (Novantrone) therapy in patients with MS.

Journal: Neurology 20020924

Title: Therapy-related acute myeloblastic leukemia after mitoxantrone treatment in a patient with MS.

Journal: Neurology 20020924

Title: Key issues in the diagnosis and treatment of multiple sclerosis. An overview.

Journal: Neurology 20020924

Title: Use of peptide antibodies to probe for the mitoxantrone resistance-associated protein MXR/BCRP/ABCP/ABCG2.

Journal: Biochimica et biophysica acta 20020920

Title: Reduced-dose cladribine (2-CdA) plus mitoxantrone is effective in the treatment of mantle-cell and low-grade non-Hodgkin's lymphoma.

Journal: European journal of cancer (Oxford, England : 1990) 20020901

Title: Spontaneous and drug-induced apoptosis is mediated by conformational changes of Bax and Bak in B-cell chronic lymphocytic leukemia.

Journal: Blood 20020901

Title: Randomized trial of 8-week versus 12-week VNCOP-B plus G-CSF regimens as front-line treatment in elderly aggressive non-Hodgkin's lymphoma patients.

Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20020901

Title: Intensive chemotherapy in patients with chronic myelogenous leukaemia (CML) in accelerated or blastic phase--a report from the Swedish CML Group.

Journal: British journal of haematology 20020901

Title: Fludarabine, ara-C, novantrone and dexamethasone (FAND) in previously treated chronic lymphocytic leukemia patients.

Journal: Haematologica 20020901

Title: Melphalan-prednisone versus alternating combination VAD/MP or VND/MP as primary therapy for multiple myeloma: final analysis of a randomized clinical study.

Journal: Haematologica 20020901

Title: Acute myocardial infarction as the presenting symptom of acute myeloblastic leukemia with extreme hyperleukocytosis.

Journal: American journal of hematology 20020901

Title: Chemotherapy for prostate cancer.

Journal: Urology 20020901

Title: Evaluation of apoptosis induced in vitro by cladribine (2-CdA) combined with anthracyclines in lymphocytes from patients with B-cell chronic lymphocytic leukemia.

Journal: Annals of hematology 20020901

Title: A phase II study of dose-dense docetaxel and mitoxantrone in the treatment of patients with high-risk metastatic breast cancer.

Journal: Anti-cancer drugs 20020901

Title: Updated meta analysis finds that interferon-alpha improves progression-free and overall survival in low-grade non-Hodgkin's lymphoma when administered with chemotherapy that contains anthracycline or mitoxantrone.

Journal: Clinical lymphoma 20020901

Title: Mitoxantrone/ifosfamide/etoposide salvage regimen with rituximab for in vivo purging in patients with relapsed lymphoma.

Journal: Clinical lymphoma 20020901

Title: Overexpression of the atypical protein kinase C zeta reduces topoisomerase II catalytic activity, cleavable complexes formation, and drug-induced cytotoxicity in monocytic U937 leukemia cells.

Journal: The Journal of biological chemistry 20020830

Title: Primary squamous cell carcinoma of the prostate: a novel chemotherapy regimen.

Journal: The Journal of urology 20020801

Title: Calcitriol (1,25-dihydroxycholecalciferol) potentiates activity of mitoxantrone/dexamethasone in an androgen independent prostate cancer model.

Journal: The Journal of urology 20020801

Title: Intensified double induction therapy with high dose mitoxantrone, etoposide, m-amsacrine and high dose ara-C for elderly acute myeloid leukemia patients aged 61-65 years.

Journal: Haematologica 20020801

Title: A relapsed non-Hodgkin lymphoma presenting as panhypopituitarism successfully treated by chemotherapy.

Journal: Journal of neuro-oncology 20020801

Title: [Immunosuppressants and multiple sclerosis].

Journal: Revista de neurologia 20020801

Title: Segmental coecal cytomegalovirus colitis during fludarabine, cytarabine and mitoxantrone induction chemotherapy for myelodysplastic syndrome.

Journal: Leukemia & lymphoma 20020801

Title: Modulation of the atypical multidrug-resistant phenotype by a hammerhead ribozyme directed against the ABC transporter BCRP/MXR/ABCG2.

Journal: Cancer gene therapy 20020701

Title: Monitoring, and estimation of kinetic data, by piezoelectric impedance analysis, of the binding of the anticancer drug mitoxantrone to surface-immobilized DNA.

Journal: Analytical and bioanalytical chemistry 20020701

Title: Phase II trial of sequential therapy with fludarabine followed by cyclophosphamide, mitoxantrone, vincristine, and prednisone for low-grade follicular lymphomas.

Journal: American journal of hematology 20020701

Title: beta-lapachone, a novel plant product, overcomes drug resistance in human multiple myeloma cells.

Journal: Experimental hematology 20020701

Title: Multiple mechanisms confer different drug-resistant phenotypes in pancreatic carcinoma cells.

Journal: Journal of cancer research and clinical oncology 20020701

Title: Quantitative analysis of mitoxantrone by surface-enhanced resonance Raman scattering.

Journal: Analytical chemistry 20020701

Title: Re-treatment with cladribine-based regimens in relapsed patients with B-cell chronic lymphocytic leukemia. Efficacy and toxicity in comparison with previous treatment.

Journal: European journal of haematology 20020701

Title: Conjunctival chloroma (granulocytic sarcoma).

Journal: Lancet (London, England) 20020629

Title: A unique type II topoisomerase mutant that is hypersensitive to a broad range of cleavage-inducing antitumor agents.

Journal: Biochemistry 20020625

Title: [Experience with fludarabine treatment and review of the literature].

Journal: Orvosi hetilap 20020616

Title: Impact of addition of maintenance therapy to intensive induction and consolidation chemotherapy for childhood acute myeloblastic leukemia: results of a prospective randomized trial, LAME 89/91. Leucámie Aiqüe Myéloïde Enfant.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20020615

Title: Mitoxantrone and cisplatin in recurrent and/or metastatic salivary gland malignancies.

Journal: Anti-cancer drugs 20020601

Title: Flexible low-intensity combination chemotherapy for elderly patients with acute myeloid leukemia.

Journal: International journal of hematology 20020601

Title: Flow cytometric analysis of breast cancer resistance protein expression and function.

Journal: Cytometry 20020601

Title: Phase III trial of a humanized anti-CD33 antibody (HuM195) in patients with relapsed or refractory acute myeloid leukemia.

Journal: Clinical lymphoma 20020601

Title: Fludarabine combination therapy for the treatment of chronic lymphocytic leukemia.

Journal: Clinical lymphoma 20020601

Title: Anthracyclines potentiate activity against murine leukemias L1210 and P388 in vivo and in vitro.

Journal: European journal of haematology 20020601

Title: Methotrexate-associated liver toxicity in a patient with breast cancer: case report and literature review.

Journal: The Netherlands journal of medicine 20020601

Title: C421A polymorphism in the human breast cancer resistance protein gene is associated with low expression of Q141K protein and low-level drug resistance.

Journal: Molecular cancer therapeutics 20020601

Title: [Preparation of long circulating mitoxantrone liposomes and its pharmacokinetics].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20020601

Title: Expression and activity of breast cancer resistance protein (BCRP) in de novo and relapsed acute myeloid leukemia.

Journal: Blood 20020515

Title: Myocardial function in patients with multiple sclerosis treated with low-dose mitoxantrone.

Journal: The American journal of cardiology 20020515

Title: Outcomes in patients treated with gemtuzumab ozogamicin for relapsed acute myelogenous leukemia.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20020515

Title: Occupational asthma due to mitoxantrone.

Journal: Allergy 20020501

Title: Topotecan-induced topoisomerase IIalpha expression increases the sensitivity of the CML cell line K562 to subsequent etoposide plus mitoxantrone treatment.

Journal: Cancer chemotherapy and pharmacology 20020501

Title: Pharmacokinetic interactions of cyclosporine with etoposide and mitoxantrone in children with acute myeloid leukemia.

Journal: Leukemia 20020501

Title: Treatment of refractory acute leukemia with timed sequential chemotherapy using topotecan followed by etoposide + mitoxantrone (T-EM) and correlation with topoisomerase II levels.

Journal: Leukemia & lymphoma 20020501

Title: Considerations in the treatment of relapsing-remitting multiple sclerosis.

Journal: Neurology 20020423

Title: High-dose chemotherapy in poor-prognosis adult small round-cell tumors: clinical and molecular results from a prospective study.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20020415

Title: Anthracyclines in the treatment of gynecologic malignancies.

Journal: Gynecologic oncology 20020401

Title: Results of an international questionnaire on immunosuppressive treatment of multiple sclerosis.

Journal: Multiple sclerosis (Houndmills, Basingstoke, England) 20020401

Title: The role of mitoxantrone in non-Hodgkin's lymphoma.

Journal: Oncology (Williston Park, N.Y.) 20020401

Title: CNOP for diffuse aggressive non-Hodgkin's lymphoma: the Nebraska lymphoma study group experience.

Journal: Leukemia & lymphoma 20020401

Title: A dose escalation study for salvage chemotherapy in patients with refractory lymphoma prior to high-dose myeloablative therapy with stem cell transplantation.

Journal: Bone marrow transplantation 20020401

Title: Potent and specific inhibition of the breast cancer resistance protein multidrug transporter in vitro and in mouse intestine by a novel analogue of fumitremorgin C.

Journal: Molecular cancer therapeutics 20020401

Title: European Organization for Research and Treatment of Cancer and Groupe d'Etude des Lymphomes de l'Adulte very favorable and favorable, lymphocyte-predominant Hodgkin disease.

Journal: Cancer 20020315

Title: Overexpression of IL-6 but not IL-8 increases paclitaxel resistance of U-2OS human osteosarcoma cells.

Journal: Cytokine 20020307

Title: Efficacy of carboplatin with an MEP (mitoxantrone, etoposide and prednisone) regimen for relapsed and CHOP-resistant diffuse large B-cell lymphomas.

Journal: Leukemia research 20020301

Title: Intraperitoneal mitoxantrone: a feasibility and pharmacokinetic study.

Journal: European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology 20020301

Title: Estrone and 17beta-estradiol reverse breast cancer resistance protein-mediated multidrug resistance.

Journal: Japanese journal of cancer research : Gann 20020301

Title: Efficacy of fludarabine/mitoxantrone/dexamethasone alternating with CHOP in bulky follicular non-Hodgkin's lymphoma.

Journal: Clinical lymphoma 20020301

Title: Treatment of intermediate- and high-grade non-Hodgkin's lymphoma using CEOP versus CNOP.

Journal: European journal of haematology 20020301

Title: Alphabet soup: a personal, evolving, mostly evidence-based and logical, sequential approach to the 'ABCNR' drugs in multiple sclerosis.

Journal: Seminars in neurology 20020301

Title: Impact of BCRP/MXR, MRP1 and MDR1/P-Glycoprotein on thermoresistant variants of atypical and classical multidrug resistant cancer cells.

Journal: International journal of cancer 20020220

Title: The modulation by xanthines of the DNA-damaging effect of polycyclic aromatic agents. Part II. The stacking complexes of caffeine with doxorubicin and mitoxantrone.

Journal: Biochemical pharmacology 20020215

Title: Chemotherapeutic stress mediated by certain antitumor antibiotics induces an atypical CD69+ surface phenotype in peripheral T-lymphocytes.

Journal: International immunopharmacology 20020201

Title: Phase I evaluation of prolonged-infusion gemcitabine with mitoxantrone for relapsed or refractory acute leukemia.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20020201

Title: A prolonged APTT in a patient with a low grade malignant NHL - a case report.

Journal: Haematologica 20020201

Title: Hematopoietic cell transplantation beyond first remission.

Journal: Leukemia 20020201

Title: Quantitative real-time polymerase chain reaction for monitoring minimal residual disease in patients with advanced indolent lymphomas treated with rituximab, fludarabine, mitoxantrone, and dexamethasone.

Journal: Seminars in oncology 20020201

Title: Higher doses of mitoxantrone among men with hormone-refractory prostate carcinoma: a Cancer and Leukemia Group B study.

Journal: Cancer 20020201

Title: Therapeutic approaches to secondary progressive multiple sclerosis.

Journal: Multiple sclerosis (Houndmills, Basingstoke, England) 20020201

Title: [Value of mitoxantrone in metastatic hormone-resistant prostate cancer].

Journal: Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie 20020201

Title: [Role of mitoxantrone in the treatment of hormone-independent metastatic cancer of the prostate].

Journal: Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie 20020201

Title: Bendamustine mitoxantrone and rituximab (BMR): a new effective regimen for refractory or relapsed indolent lymphomas.

Journal: Leukemia & lymphoma 20020201

Title: Induction of apoptosis by cladribine (2-CdA), gemcitabine and other chemotherapeutic drugs on CD34+/CD38+ and CD34+/CD38- hematopoietic progenitor cells: selective effects of doxorubicin and 2-CdA with protection of immature cells.

Journal: Leukemia & lymphoma 20020201

Title: Three-step high-dose sequential chemotherapy in patients with newly diagnosed multiple myeloma.

Journal: European journal of haematology 20020201

Title: Acute lymphocytic leukemia CNS disease presenting as central diabetes insipidus.

Journal: The Journal of the Association of Physicians of India 20020201

Title: Disease modifying therapies in multiple sclerosis: report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology and the MS Council for Clinical Practice Guidelines.

Journal: Neurology 20020122

Title: In vivo analysis of human multidrug resistance protein 1 (MRP1) activity using transient expression of fluorescently tagged MRP1.

Journal: Cancer research 20020115

Title: c-Jun N-terminal kinase/stress-activated protein kinase (JNK/SAPK) is required for mitoxantrone- and anisomycin-induced apoptosis in HL-60 cells.

Journal: Leukemia research 20020101

Title: Different drug sensitivity profiles of acute myeloid and lymphoblastic leukemia and normal peripheral blood mononuclear cells in children with and without Down syndrome.

Journal: Blood 20020101

Title: Anti-CD20 antibody (IDEC-C2B8, rituximab) enhances efficacy of cytotoxic drugs on neoplastic lymphocytes in vitro: role of cytokines, complement, and caspases.

Journal: Haematologica 20020101

Title: The multidrug resistance transporter ABCG2 (breast cancer resistance protein 1) effluxes Hoechst 33342 and is overexpressed in hematopoietic stem cells.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20020101

Title: Controversies in chemotherapy of prostate cancer.

Journal: Frontiers of radiation therapy and oncology 20020101

Title: Philadelphia chromosome-positive acute myeloid leukemia with tetraploidy.

Journal: International journal of hematology 20020101

Title: Experience with methotrexate, 5-fluorouracil, and leucovorin (MFL): a first line effective, minimally toxic regimen for metastatic breast cancer.

Journal: Cancer investigation 20020101

Title: Assessment of response by breast helical computed tomography to neoadjuvant chemotherapy in large inflammatory breast cancer.

Journal: Clinical breast cancer 20020101

Title: Primary treatment of low-grade non-Hodgkin's lymphoma with the combination of fludarabine and mitoxantrone: a phase II study of the Hellenic Cooperative Oncology Group.

Journal: Leukemia & lymphoma 20020101

Title: Treatment of non-Hodgkin's lymphoma in the elderly. The Italian studies.

Journal: Tumori 20020101

Title: Treatment of elderly Hodgkin's lymphoma patients. The experience of the Italian Lymphoma Intergroup.

Journal: Tumori 20020101

Title: The effect of doxorubicin and its analogue mitoxantrone on cardiac muscle and on serum lipids: an experimental study.

Journal: Anticancer research 20020101

Title: Timed sequential chemotherapy with concomitant granulocyte colony-stimulating factor for high-risk acute myelogenous leukemia: a single arm clinical trial.

Journal: BMC cancer 20020101

Title: Cognitive dysfunction in multiple sclerosis: natural history, pathophysiology and management.

Journal: CNS drugs 20020101

Title: [Thermodynamic analysis of interaction of mitoxantrone with deoxytetranucleotide 5'-d(TpGpCpA) in the water solution based on 1H-NMR spectrophotometry].

Journal: Biofizika 20020101

Title: ABVD versus stanford V versus MEC in unfavourable Hodgkin's lymphoma: results of a randomised trial.

Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20020101

Title: Binding free energy of selected anticancer compounds to DNA--theoretical calculations.

Journal: Journal of molecular modeling 20020101

Title: Lactic acid based PEU/HA and PEU/BCP composites: Dynamic mechanical characterization of hydrolysis.

Journal: Journal of biomedical materials research 20020101

Title: A comparison of the in vitro genotoxicity of anticancer drugs idarubicin and mitoxantrone.

Journal: Acta biochimica Polonica 20020101

Title: Inv(4)(p14q27) in a case with de novo acute nonlymphocytic leukemia.

Journal: Acta haematologica 20020101

Title: CD7+ and CD56+ myeloid/natural killer cell precursor acute leukemia treated with idarubicin and cytosine arabinoside.

Journal: Acta haematologica 20020101

Title: The antineoplastic treatment in the elderly.

Journal: La Clinica terapeutica 20020101

Title: [Effect of intercalators on the properties of liquid-crystalline dispersions of nucleic acid-chitosan complex].

Journal: Molekuliarnaia biologiia 20020101

Title: [Post-marketing surveillance information transmitted via electronic mail in a University Hospital].

Journal: Therapie 20020101

Title: A long-term survival case underwent repeated hepatic arterial infusion chemotherapy with portal branch ligation and wrapping of the liver using sheets for hepatocellular carcinoma.

Journal: Hepato-gastroenterology 20020101

Title: Treatment of blastic phase chronic myeloid leukemia with mitoxantrone, cytosine arabinoside and high dose methylprednisolone.

Journal: Haematologia 20020101

Title: Acute myelogenous leukaemia in older patients at St Bartholomew's Hospital: outcome with mitoxantrone and cytarabine.

Journal: The hematology journal : the official journal of the European Haematology Association 20020101

Title: P-glycoprotein expression by cancer cells affects cell cytotoxicity and cell-cycle perturbations induced by six chemotherapeutic drugs.

Journal: Journal of experimental therapeutics & oncology 20020101

Title: Loss of growth factor sensitivity and development of mitoxantrone resistance in transplanted recurrent SA7HD myeloid leukemia.

Journal: Journal of experimental therapeutics & oncology 20020101

Title: Evaluation of the in vitro cytotoxicity of mitoxantrone following repeated freeze-thaw cycles.

Journal: Veterinary therapeutics : research in applied veterinary medicine 20020101

Title: Paclitaxel and mitoxantrone in the treatment of metastatic breast cancer: a phase II trial of the Minnie Pearl Cancer Research Network.

Journal: Cancer investigation 20020101

Title: The treatment of acute myeloid leukemia with mitoxantrone, etoposide and low-dose cytarabine in elderly patients - a report of Polish Acute Leukemia Group (PALG) phase II study.

Journal: Neoplasma 20020101

Title: Superior outcome of infant acute myeloid leukemia with intensive chemotherapy: results of the Japan Infant Leukemia Study Group.

Journal: Blood 20011215

Title: Locally advanced primary breast cancer: medium-term results of a randomised trial of multimodal therapy versus initial hormone therapy.

Journal: European journal of cancer (Oxford, England : 1990) 20011201

Title: A phase I dose-finding study of combined treatment with an antisense Bcl-2 oligonucleotide (Genasense) and mitoxantrone in patients with metastatic hormone-refractory prostate cancer.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20011201

Title: Regional chemotherapy of nonresectable colorectal liver metastases with mitoxantrone, 5-fluorouracil, folinic acid, and mitomycin C may prolong survival.

Journal: Cancer 20011201

Title: A double-blind clinical trial of mitoxantrone versus methylprednisolone in relapsing, secondary progressive multiple sclerosis.

Journal: Acta neurologica Belgica 20011201

Title: Unrelated cord blood transplantation for an infant with chemotherapy-resistant progressive Langerhans cell histiocytosis.

Journal: Journal of pediatric hematology/oncology 20011201

Title: [Recent therapeutic strategy for multiple sclerosis].

Journal: Rinsho shinkeigaku = Clinical neurology 20011201

Title: High-dose mitoxantrone and cyclophosphamide without stem cell support in patients with high-risk and advanced breast carcinoma: a Phase II multicentric trial.

Journal: Cancer 20011115

Title: Intravenous chemotherapy, early debulking surgery, and consolidation intraperitoneal chemotherapy in advanced ovarian carcinoma.

Journal: Gynecologic oncology 20011101

Title: Infectious complications in breast cancer patients undergoing peripheral blood stem cell transplantation: a single center retrospective analysis towards outpatient strategy.

Journal: Bone marrow transplantation 20011101

Title: Primary progressive multiple sclerosis.

Journal: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20011101

Title: Intensive chemotherapy followed by allogeneic or autologous stem cell transplantation for patients with myelodysplastic syndromes (MDSs) and acute myeloid leukemia following MDS.

Journal: Blood 20011015

Title: Mitoxantrone in patients with prostate specific antigen progression after local therapy for prostate carcinoma.

Journal: Cancer 20011015

Title: Hydrogels for combination delivery of antineoplastic agents.

Journal: Biomaterials 20011001

Title: Cladribine combined with cyclophosphamide and mitoxantrone as front-line therapy in chronic lymphocytic leukemia.

Journal: Leukemia 20011001

Title: In vitro effects of dexrazoxane (Zinecard) and classical acute leukemia therapy: time to consider expanded clinical trials?

Journal: Leukemia 20011001

Title: Phosphodiesterase type 4 inhibitor suppresses expression of anti-apoptotic members of the Bcl-2 family in B-CLL cells and induces caspase-dependent apoptosis.

Journal: Leukemia 20011001

Title: [Combination chemotherapy with VP-16 in the treatment of lung cancer and malignant lymphoma].

Journal: Gan to kagaku ryoho. Cancer & chemotherapy 20011001

Title: Patterns of chemotherapy administration in patients with intermediate-grade non-Hodgkin's lymphoma.

Journal: Oncology (Williston Park, N.Y.) 20011001

Title: Donor cell-derived acute myeloid leukemia developing 14 months after matched unrelated bone marrow transplantation for chronic myeloid leukemia.

Journal: Bone marrow transplantation 20011001

Title: The use of serum levels of cardiac troponin T to compare the protective activity of dexrazoxane against doxorubicin- and mitoxantrone-induced cardiotoxicity.

Journal: Cancer chemotherapy and pharmacology 20011001

Title: Fludarabine and mitoxantrone: effective and well-tolerated salvage therapy in relapsed indolent lymphoproliferative disorders.

Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20011001

Title: FAB M4 and high CD14 surface expression is associated with high cellular resistance to Ara-C and daunorubicin: implications for clinical outcome in acute myeloid leukaemia.

Journal: European journal of haematology 20011001

Title: Intracavitary therapies for mesothelioma.

Journal: Current treatment options in oncology 20011001

Title: Reduction in drug-induced DNA double-strand breaks associated with beta1 integrin-mediated adhesion correlates with drug resistance in U937 cells.

Journal: Blood 20010915

Title: Acquired mutations in the MXR/BCRP/ABCP gene alter substrate specificity in MXR/BCRP/ABCP-overexpressing cells.

Journal: Cancer research 20010915

Title: University of Washington high-dose cyclophosphamide, mitoxantrone, and etoposide experience in metastatic breast cancer: unexpected cardiac toxicity.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20010915

Title: [New approaches in research of therapy of multiple sclerosis].

Journal: Medizinische Klinik (Munich, Germany : 1983) 20010915

Title: Attempts to improve treatment outcomes in acute myeloid leukemia (AML) in older patients: the results of the United Kingdom Medical Research Council AML11 trial.

Journal: Blood 20010901

Title: Cost-effectiveness analysis with risk aversion.

Journal: Health economics 20010901

Title: Establishment of two vaccine-associated feline sarcoma cell lines and determination of in vitro chemosensitivity to doxorubicin and mitoxantrone.

Journal: American journal of veterinary research 20010901

Title: Altered topoisomerase IIalpha and multidrug resistance-associated protein levels during drug selection: adaptations to increasing drug pressure.

Journal: Japanese journal of cancer research : Gann 20010901

Title: Prostate cancer in the older man.

Journal: Oncology (Williston Park, N.Y.) 20010901

Title: [Comparison of the effectiveness of idarubicin (Zavedos) and mitoxantrone (Refador) in induction therapy of acute myeloid leukemia in elderly patients (55-75) (a prospective multicenter randomized study conducted 1998-2000].

Journal: Vnitrni lekarstvi 20010901

Title: Enhanced expression of human ABC-transporter tap is associated with cellular resistance to mitoxantrone.

Journal: FEBS letters 20010817

Title: Resistance to topoisomerase poisons due to loss of DNA mismatch repair.

Journal: International journal of cancer 20010815

Title: A leukemic stem cell with intrinsic drug efflux capacity in acute myeloid leukemia.

Journal: Blood 20010815

Title: A novel 7-modified camptothecin analog overcomes breast cancer resistance protein-associated resistance in a mitoxantrone-selected colon carcinoma cell line.

Journal: Cancer research 20010815

Title: The DNA helicase activity of yeast Sgs1p is essential for normal lifespan but not for resistance to topoisomerase inhibitors.

Journal: Mechanisms of ageing and development 20010801

Title: Postremission therapy in older patients with de novo acute myeloid leukemia: a randomized trial comparing mitoxantrone and intermediate-dose cytarabine with standard-dose cytarabine.

Journal: Blood 20010801

Title: CMF (cyclophosphamide, methotrexate, 5-fluorouracil) versus cnf (cyclophosphamide, mitoxantrone, 5-fluorouracil) as adjuvant chemotherapy for stage II lymph-node positive breast cancer: a phase III randomized multicenter study.

Journal: American journal of clinical oncology 20010801

Title: Treatment of aggressive non-Hodgkin's lymphoma in elderly patients with thiotepa, Novantrone (mitoxantrone), vincristine, prednisone (TNOP).

Journal: American journal of clinical oncology 20010801

Title: Treatment of hormone refractory prostate cancer.

Journal: Seminars in urologic oncology 20010801

Title: Can chemotherapy alter the course of prostate cancer?

Journal: Seminars in urologic oncology 20010801

Title: Complications of chemotherapy for prostate cancer.

Journal: Seminars in urologic oncology 20010801

Title: Mito-flag as salvage therapy for relapsed and refractory acute myeloid leukemia.

Journal: Onkologie 20010801

Title: Perioperative locoregional application of mitoxantrone in patients with early breast carcinoma.

Journal: Journal of chemotherapy (Florence, Italy) 20010801

Title: Amifostine does not inhibit the toxic effects of anthracycline derivates or mitoxantrone on MDR tumor cell lines.

Journal: Leukemia & lymphoma 20010801

Title: Mitoxantrone: new indication. More risky than beneficial in advanced prostate cancer.

Journal: Prescrire international 20010801

Title: Efficacy of intratumoral delivery of mitoxantrone in recurrent malignant glial tumours.

Journal: Journal of neuro-oncology 20010801

Title: Resistance to mitoxantrone in multidrug-resistant MCF7 breast cancer cells: evaluation of mitoxantrone transport and the role of multidrug resistance protein family proteins.

Journal: Cancer research 20010715

Title: Detection of human herpesvirus 6 and JC virus in progressive multifocal leukoencephalopathy complicating follicular lymphoma.

Journal: American journal of hematology 20010701

Title: Radiation therapy after a partial response to CHOP chemotherapy for aggressive lymphomas.

Journal: International journal of radiation oncology, biology, physics 20010701

Title: Ifosfamide- and etoposide-based chemotherapy as salvage and mobilizing regimens for poor prognosis lymphoma.

Journal: European journal of haematology. Supplementum 20010701

Title: Rituximab and ifosfamide, mitoxantrone, etoposide (RIME) with Neupogen support for B-cell non-Hodgkin's lymphoma prior to high-dose chemotherapy with autologous haematopoietic transplant.

Journal: European journal of haematology. Supplementum 20010701

Title: Combination therapy with irinotecan (CPT-11), mitoxantrone, and dexamethasone in relapsed or refractory non-Hodgkin's lymphoma: a pilot study.

Journal: Annals of hematology 20010701

Title: Incremental net benefit in randomized clinical trials.

Journal: Statistics in medicine 20010615

Title: A functional assay for detection of the mitoxantrone resistance protein, MXR (ABCG2).

Journal: Biochimica et biophysica acta 20010606

Title: Esters of 2-(1-hydroxyalkyl)-1,4-dihydroxy-9,10-anthraquinones with melphalan as multifunctional anticancer agents.

Journal: Bioorganic & medicinal chemistry letters 20010604

Title: Results of a phase III prospective, randomised trial, comparing mitoxantrone and vinorelbine (MV) in combination with standard FAC/FEC in front-line therapy of metastatic breast cancer.

Journal: European journal of cancer (Oxford, England : 1990) 20010601

Title: Magnetic resonance imaging detection of avascular necrosis of the bone in children receiving intensive prednisone therapy for acute lymphoblastic leukemia or non-Hodgkin lymphoma.

Journal: Leukemia 20010601

Title: The prognostic value of cytogenetics is reinforced by the kind of induction/consolidation therapy in influencing the outcome of acute myeloid leukemia--analysis of 848 patients.

Journal: Leukemia 20010601

Title: Secondary acute myelogenous leukemia and myelodysplasia without abnormalities of chromosome 11q23 following treatment of acute leukemia with topoisomerase II-based chemotherapy.

Journal: Leukemia 20010601

Title: Efficacy of fludarabine, intermittent sequential high-dose cytosine arabinoside, and mitoxantrone (FIS-HAM) salvage therapy in highly resistant acute leukemias.

Journal: Annals of hematology 20010601

Title: A retrospective analysis of the relationship between changes in serum PSA, palliative response and survival following systemic treatment in a Canadian randomized trial for symptomatic hormone-refractory prostate cancer.

Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20010601

Title: Docetaxel in combination with mitoxantrone and granulocyte colony-stimulating factor as front-line chemotherapy in metastatic breast cancer: a multicenter phase II study.

Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20010601

Title: Cost of de novo acute myeloid leukemia induction therapy in adults: analysis of EORTC-GIMEMA AML10 and FLANG regimens.

Journal: Journal of experimental & clinical cancer research : CR 20010601

Title: From MDR to MXR: new understanding of multidrug resistance systems, their properties and clinical significance.

Journal: Cellular and molecular life sciences : CMLS 20010601

Title: Paclitaxel and docetaxel in prostate cancer.

Journal: Hematology/oncology clinics of North America 20010601

Title: Mitoxantrone is superior to doxorubicin in a multiagent weekly regimen for patients older than 60 with high-grade lymphoma: results of a BNLI randomized trial of PAdriaCEBO versus PMitCEBO.

Journal: Blood 20010515

Title: Improved treatment results in high-risk pediatric acute myeloid leukemia patients after intensification with high-dose cytarabine and mitoxantrone: results of Study Acute Myeloid Leukemia-Berlin-Frankfurt-Münster 93.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20010515

Title: Cytosine methylation enhances mitoxantrone-DNA adduct formation at CpG dinucleotides.

Journal: The Journal of biological chemistry 20010511

Title: Atp-bound topoisomerase ii as a target for antitumor drugs.

Journal: The Journal of biological chemistry 20010511

Title: Combined action of PSC 833 (Valspodar), a novel MDR reversing agent, with mitoxantrone, etoposide and cytarabine in poor-prognosis acute myeloid leukemia.

Journal: Leukemia 20010501

Title: Estrogen-receptor-directed neoadjuvant therapy for breast cancer: results of a randomised trial using formestane and methotrexate, mitozantrone and mitomycin C (MMM) chemotherapy.

Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20010501

Title: Longitudinal effects of high-dose chemotherapy and autologous stem cell transplantation on quality of life in the treatment of metastatic breast cancer.

Journal: Bone marrow transplantation 20010501

Title: Acute metabolic alkalosis enhances response of C3H mouse mammary tumors to the weak base mitoxantrone.

Journal: Neoplasia (New York, N.Y.) 20010501

Title: Immunologic therapy for relapsing-remitting multiple sclerosis.

Journal: Current neurology and neuroscience reports 20010501

Title: Immunologic therapy for secondary and primary progressive multiple sclerosis.

Journal: Current neurology and neuroscience reports 20010501

Title: HPV16-E6 enhances mitoxantrone sensitivity in a human ovarian cancer line: an isolated instance or a trend?

Journal: International journal of oncology 20010401

Title: Complications associated with intraperitoneal chemotherapy catheters.

Journal: Gynecologic oncology 20010401

Title: Combination chemotherapy with mitoxantrone, methotrexate, and mitomycin (MMM regimen) in malignant pleural mesothelioma: a phase II study.

Journal: American journal of clinical oncology 20010401

Title: Immunomodulatory drugs for multiple sclerosis: a systematic review of clinical and cost effectiveness.

Journal: Expert opinion on pharmacotherapy 20010401

Title: High remission rate in acute myeloblastic leukemia with only two days of chemotherapy.

Journal: Leukemia & lymphoma 20010401

Title: Acute promyelocytic leukemia with additional chromosome abnormalities in a renal transplant case.

Journal: Annals of hematology 20010401

Title: Double reinforcement with fludarabine/high-dose cytarabine enhances the impact of autologous stem cell transplantation in acute myeloid leukemia patients.

Journal: Bone marrow transplantation 20010401

Title: Fludarabine in combination with cyclophosphamide or with cyclophosphamide plus mitoxantrone for relapsed or refractory low-grade non-Hodgkin's lymphoma.

Journal: Haematologica 20010301

Title: Optimal timing and dosage of chemotherapy as a combined treatment with androgen withdrawal in the human prostate LNCaP tumour model.

Journal: British journal of cancer 20010301

Title: Ifosfamide and mitoxantrone in the treatment of recurrent and/or metastatic squamous cell carcinoma of the head and neck.

Journal: Anti-cancer drugs 20010301

Title: Neutrophilic eccrine hidradenitis in two neutropaenic patients.

Journal: Clinical and experimental dermatology 20010301

Title: Treatment of elderly patients with intermediate- and high-grade non-Hodgkin's lymphoma: a retrospective population-based study.

Journal: Annals of hematology 20010301

Title: Selection and characterization of a high-activity ribozyme directed against the antineoplastic drug resistance-associated ABC transporter BCRP/MXR/ABCG2.

Journal: Cancer gene therapy 20010301

Title: Cemp, a mitoxantrone containing combination, in the treatment of intermediate and high grade non-hodgkin's lymphoma: an effective and non toxic therapeutic alternative for adult and elderly patients.

Journal: Leukemia & lymphoma 20010301

Title: Pretreatment leukaemia cell drug resistance is correlated to clinical outcome in acute myeloid leukaemia.

Journal: European journal of haematology 20010301

Title: Cladribine in combination with mitoxantrone and cyclophosphamide(CMC) in the treatment of heavily pre-treated patients with advanced indolent lymphoid malignancies.

Journal: European journal of haematology 20010301

Title: Secondary leukemia after adjuvant chemotherapy for breast cancer.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20010215

Title: Anthracycline adjuvant chemotherapy: how much is enough?

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20010201

Title: Intensification of adjuvant chemotherapy: 5-year results of a randomized trial comparing conventional doxorubicin and cyclophosphamide with high-dose mitoxantrone and cyclophosphamide with filgrastim in operable breast cancer with 10 or more involved axillary nodes.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20010201

Title: Elderly ovarian cancer: treatment with mitoxantrone-carboplatin.

Journal: Gynecologic oncology 20010201

Title: [Is it useful to perform a (67)gallium scintigraphy in the follow-up of patients with gastric lymphoma?].

Journal: Revista espanola de medicina nuclear 20010201

Title: Chemotherapy for acute myelogenous leukemia in the elderly with cytarabine, mitoxantrone, and granulocyte-macrophage colony-stimulating factor.

Journal: American journal of clinical oncology 20010201

Title: High-dose mitoxantrone + melphalan (MITO/L-PAM) as conditioning regimen supported by peripheral blood progenitor cell (PBPC) autograft in 113 lymphoma patients: high tolerability with reversible cardiotoxicity.

Journal: Leukemia 20010201

Title: Induction therapy of adult acute lymphocytic leukemia without the use of vincristine or prednisone.

Journal: Hematology/oncology clinics of North America 20010201

Title: [Escalating immunomodulatory therapy of multiple sclerosis. 1st supplement: December 2000].

Journal: Der Nervenarzt 20010201

Title: Multiple sclerosis treatment 2001.

Journal: Neurologic clinics 20010201

Title: [Conjugation of mitoxantrone-loaded nanospheres and anti-C-erbB-2 monoclonal antibodies].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20010201

Title: Inhibition of BCRP-mediated drug efflux by fumitremorgin-type indolyl diketopiperazines.

Journal: Bioorganic & medicinal chemistry letters 20010108

Title: Chemotherapy and marrow transplantation for congenital leukaemia.

Journal: Archives of disease in childhood. Fetal and neonatal edition 20010101

Title: DNA-interactive anticancer aza-anthrapyrazoles: biophysical and biochemical studies relevant to the mechanism of action.

Journal: Molecular pharmacology 20010101

Title: The role of laparoscopy in second-look evaluations for ovarian cancer.

Journal: Gynecologic oncology 20010101

Title: Serum LDH, a prognostic factor in elderly patients with acute myelogenous leukaemia.

Journal: British journal of cancer 20010101

Title: Patients with de novo acute myeloid leukaemia and complex karyotype aberrations show a poor prognosis despite intensive treatment: a study of 90 patients.

Journal: British journal of haematology 20010101

Title: DNA topoisomerase II inhibition by peroxisomicine A(1) and its radical metabolite induces apoptotic cell death of HL-60 and HL-60/MX2 human leukemia cells.

Journal: Chemical research in toxicology 20010101

Title: 5'-deoxy-5-fluorouridine, medroxyprogestrone acetate and mitoxantrone hydrochloride for advanced or recurrent breast cancer.

Journal: Breast cancer (Tokyo, Japan) 20010101

Title: Overexpression of the ATP-binding cassette half-transporter, ABCG2 (Mxr/BCrp/ABCP1), in flavopiridol-resistant human breast cancer cells.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20010101

Title: Phase I study of mitoxantrone, raltitrexed, levofolinic acid and 5-fluorouracil in advanced solid tumours.

Journal: Cancer chemotherapy and pharmacology 20010101

Title: High-dose mitoxantrone and cyclophosphamide without stem cell support in high-risk and advanced solid tumors: a phase I trial.

Journal: Bone marrow transplantation 20010101

Title: Clinical assessment of a chemosensitivity assay as a treatment planning tool for dogs with cancer.

Journal: Journal of the American Animal Hospital Association 20010101

Title: The efficacy of combination chemotherapy including intraperitoneal cisplatinum and mitoxantrone with intravenous ifosfamide in patients with FIGO stage I C ovarian carcinoma.

Journal: European journal of gynaecological oncology 20010101

Title: Mitoxantrone and paclitaxel combination chemotherapy in metastatic breast cancer.

Journal: Cancer investigation 20010101

Title: Combination therapy of percutaneous mitoxantrone injection, percutaneous ethanol injection, and transcatheter arterial embolization for intrahepatic hepatocellular carcinoma and adrenal metastasis.

Journal: Hepato-gastroenterology 20010101

Title: Salvage chemotherapy with mitoxantrone, fludarabine, cytarabine, and cisplatin (MIFAP) in relapsing and refractory lymphoma.

Journal: Journal of cancer research and clinical oncology 20010101

Title: Phase II study of combination human recombinant GM-CSF with intermediate-dose cytarabine and mitoxantrone chemotherapy in patients with high-risk myelodysplastic syndromes (RAEB, RAEBT, and CMML): an Eastern Cooperative Oncology Group Study.

Journal: American journal of hematology 20010101

Title: Mitoxantrone and fludarabine in the treatment of patients with non-Hodgkin's lymphoma failing primary therapy with a doxorubicinor mitoxantrone-containing regimen.

Journal: Leukemia & lymphoma 20010101

Title: A systematic overview of chemotherapy effects in acute myeloid leukaemia.

Journal: Acta oncologica (Stockholm, Sweden) 20010101

Title: Intensive postremission chemotherapy in Taiwanese adults with acute myelogenous leukemia.

Journal: Advances in therapy 20010101

Title: Pharmaco-economic study of intensive chemotherapy with peripheral blood progenitor cell support for advanced breast cancer.

Journal: Oncology reports 20010101

Title: [Improved treatment results in children with AML: Results of study AML-BFM 93].

Journal: Klinische Padiatrie 20010101

Title: Cladribine combined with mitoxantrone in the treatment of blastic phase of chronic myeloid leukemia.

Journal: Neoplasma 20010101

Title: T-cell-rich B-cell lymphoma. Analysis of clinical features, response to treatment, survival and comparison with diffuse large B-cell lymphoma.

Journal: Oncology 20010101

Title: Treatment options in hormone-refractory prostate cancer: current and future approaches.

Journal: Drugs 20010101

Title: Improved safety, pharmacokinetics and therapeutic efficacy profiles of a novel liposomal formulation of mitoxantrone.

Journal: Anticancer research 20010101

Title: Outcome is not improved by the use of alternating chemotherapy in elderly patients with aggressive lymphoma.

Journal: The hematology journal : the official journal of the European Haematology Association 20010101

Title: Drug helps delay progression of multiple sclerosis.

Journal: FDA consumer 20010101

Title: Bbr 2778, an aza-anthracenedione endowed with preclinical anticancer activity and lack of delayed cardiotoxicity.

Journal: Tumori 20010101

Title: Sinus bradycardia secondary to mitoxantrone.

Journal: Missouri medicine 20000601

Title: Treatment of patients with recurrent and primary refractory acute myelogenous leukemia using mitoxantrone and intermediate-dose cytarabine: a pharmacologically based regimen.

Journal: Cancer 20000501

Title: Sinus bradycardia due to mitoxantrone.

Journal: Southern medical journal 20000401

Title: Effects of protein binding on the in vitro activity of antitumour acridine derivatives and related anticancer drugs.

Journal: Cancer chemotherapy and pharmacology 20000101

Title: First-line treatment of metastatic breast cancer with mitoxantrone, vinorelbine, and carboplatin.

Journal: American journal of clinical oncology 19991201

Title: Camptothecin resistance: role of the ATP-binding cassette (ABC), mitoxantrone-resistance half-transporter (MXR), and potential for glucuronidation in MXR-expressing cells.

Journal: Cancer research 19991201

Title: Toxicity of a particulate formulation for the intraperitoneal application of mitoxantrone.

Journal: International journal of pharmaceutics 19990415

Title: Efficacy of dexrazoxane as a cardioprotective agent in patients receiving mitoxantrone- and daunorubicin-based chemotherapy.

Journal: Seminars in oncology 19980801

Title: Fas ligand is constitutively secreted by prostate cancer cells in vitro.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 19980701

Title: A phase I-II study of high-dose melphalan, mitoxantrone and carboplatin with peripheral blood stem cell support in patients with advanced ovarian or breast carcinoma.

Journal: Bone marrow transplantation 19971101

Title: [Mitoxantrone-induced acute left heart failure after intrapleural administration].

Journal: Herz 19970801

Title: S-HAM induction chemotherapy with or without GM-CSF in patients with high-risk myelodysplastic syndromes.

Journal: Annals of hematology 19970501

Title: Mitoxantrone-induced bradycardia.

Journal: Annals of internal medicine 19970301

Title: Pericarditis induced by high-dose cytosine arabinoside chemotherapy.

Journal: Annals of hematology 19970101

Title: Cerebellar toxicity with medium-dose cytarabine in a young patient with renal insufficiency.

Journal: American journal of hematology 19961101

Title: Overexpression of Bcl-2 or Bcl-xL inhibits Ara-C-induced CPP32/Yama protease activity and apoptosis of human acute myelogenous leukemia HL-60 cells.

Journal: Cancer research 19961015

Title: Bradycardia due to mitoxantrone exacerbated by previous anthracycline therapy.

Journal: American journal of hematology 19960801

Title: Therapy-related leukemia with a novel 21q22 rearrangement.

Journal: Cancer genetics and cytogenetics 19960801

Title: [Severe 5-fluorouracil toxicity in a woman treated for breast cancer with concurrent osteogenesis imperfecta and dehydrogenase deficiency].

Journal: Bulletin du cancer 19960401

Title: Expression of inducible nitric oxide synthase in failing and non-failing human heart.

Journal: Journal of molecular and cellular cardiology 19960101

Title: Comparison of mitozantrone and epirubicin in advanced breast cancer.

Journal: Clinical oncology (Royal College of Radiologists (Great Britain)) 19960101

Title: Rhabdomyolysis: an unusual complication of cytotoxic chemotherapy.

Journal: Medical oncology (Northwood, London, England) 19951201

Title: High-dose chemotherapy combined with escalating doses of cyclosporin A and an autologous bone marrow transplant for the treatment of drug-resistant solid tumors: a phase I clinical trial.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 19951201

Title: [Long-term selective beta 1-blockade therapy for a patient with anthracycline-induced cardiomyopathy].

Journal: [Rinsho ketsueki] The Japanese journal of clinical hematology 19951101

Title: Amino-substituted 2-[2'-(dimethylamino)ethyl]-1,2-dihydro-3H- dibenz[de,h]isoquinoline-1,3-diones. Synthesis, antitumor activity, and quantitative structure--activity relationship.

Journal: Journal of medicinal chemistry 19950317

Title: Post-remission cytopenias following intense induction chemotherapy for acute myeloid leukemia.

Journal: Leukemia 19940401

Title: Intensive conventional-dose chemotherapy for stage IV low-grade lymphoma: high remission rates and reversion to negative of peripheral blood bcl-2 rearrangement.

Journal: Annals of oncology : official journal of the European Society for Medical Oncology 19940101

Title: High-dose mitoxantrone induces programmed cell death or apoptosis in human myeloid leukemia cells.

Journal: Blood 19931115

Title: Late cardiac toxicity of doxorubicin, epirubicin, and mitoxantrone therapy for Hodgkin's disease in adults.

Journal: Leukemia & lymphoma 19931001

Title: Myocyte cell damage after administration of doxorubicin or mitoxantrone in breast cancer patients assessed by indium 111 antimyosin monoclonal antibody studies.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 19930701

Title: [Superselective intra-arterial chemotherapy in breast cancer].

Journal: Der Radiologe 19930501

Title: Characterization of experimental mitoxantrone cardiotoxicity and its partial inhibition by ICRF-187 in cultured neonatal rat heart cells.

Journal: Cancer research 19930201

Title: A toxic interaction between mitomycin C and tamoxifen causing the haemolytic uraemic syndrome.

Journal: European journal of cancer (Oxford, England : 1990) 19930101

Title: Intravesical mitoxantrone in superficial bladder tumours (Ta-T1).

Journal: European journal of cancer (Oxford, England : 1990) 19930101

Title: Mitoxantrone (dihydroxyanthracenedione) in acute leukemia. An evaluation of two treatment schedules by the Southwest Oncology Group.

Journal: Investigational new drugs 19930101

Title: Reversible cardiopathy after accidental overdose of mitoxantrone.

Journal: Pediatric hematology and oncology 19930101

Title: Fulminant hepatic failure after high-dose cytosine arabinoside and mitoxantrone treatment for relapse of acute myelogenous leukaemia.

Journal: European journal of haematology 19921001

Title: Phase II trial of mitoxantrone in head and neck carcinoma.

Journal: American journal of clinical oncology 19910801

Title: A phase I trial of 14-day continuous intravenous infusion mitoxantrone.

Journal: Anti-cancer drugs 19910601

Title: Ventricular late potentials in the assessment of mitoxantrone cardiotoxicity.

Journal: Cardiology 19910101

Title: A phase I-II study of high-dose cyclophosphamide, thiotepa and escalating doses of mitoxantrone with autologous stem cell rescue in patients with refractory malignancies.

Journal: Bone marrow transplantation 19901201

Title: High activity of daily-schedule mitoxantrone in newly diagnosed low-grade non-Hodgkin's lymphomas: a 5-year follow-up.

Journal: Seminars in oncology 19901201

Title: [Even mitoxantrone can cause local skin necrosis].

Journal: Lakartidningen 19900117

Title: Discoloration of the nails and early anemia after mitoxantrone, folinic acid and 5-fluorouracil.

Journal: Medical oncology and tumor pharmacotherapy 19900101

Title: Randomized clinical trial comparing mitoxantrone with doxorubicin in previously treated patients with metastatic breast cancer.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 19890501

Title: Warning against use of intrathecal mitoxantrone.

Journal: Lancet (London, England) 19890401

Title: Mitoxantrone induced congestive heart failure in patients previously treated with anthracyclines.

Journal: British journal of haematology 19890201

Title: Salvage of relapsed malignant histiocytosis by autologous bone marrow transplant.

Journal: Bone marrow transplantation 19890101

Title: [Evaluation of ventricular function in patients treated with mitoxantrone and 4'-epidoxorubicin].

Journal: Archivos del Instituto de Cardiologia de Mexico 19890101

Title: Evaluation of ventricular function by echocardiography and radionuclide angiography in patients treated with mitoxantrone.

Journal: Drugs under experimental and clinical research 19890101

Title: Treatment of refractory or relapsed adult acute leukemia by using mitoxantrone-containing regimens.

Journal: Taiwan yi xue hui za zhi. Journal of the Formosan Medical Association 19890101

Title: Cardiotoxicity of mitozantrone assessed by stress and resting nuclear ventriculography.

Journal: European journal of cancer & clinical oncology 19880501

Title: Primary chemotherapy with mitoxantrone and prednisone in advanced breast carcinoma. A phase II study.

Journal: European journal of cancer & clinical oncology 19880301

Title: Mitoxantrone: an active, new antitumor agent with an improved therapeutic index.

Journal: Cancer treatment reviews 19871201

Title: Toxicity evaluation of dihydroxyanthracenedione (DHAD) in combination with cytosine arabinoside (Ara-C).

Journal: Investigational new drugs 19871201

Title: Mitoxantrone in the treatment of patients with non-Hodgkin's Lymphoma.

Journal: Cancer treatment reports 19871201

Title: A case of mitozantrone-associated cardiomyopathy without prior anthracycline therapy.

Journal: The British journal of radiology 19871101

Title: Combined mitoxantrone plus doxorubicin in the treatment of breast cancer.

Journal: American journal of clinical oncology 19870801

Title: High-dose cytosine arabinoside and mitoxantrone: a highly effective regimen in refractory acute myeloid leukemia.

Journal: Blood 19870301

Title: Paraplegia after intrathecal mitozantrone.

Journal: Lancet (London, England) 19861213

Title: Reversible bilateral lateral rectus muscle palsy associated with high-dose cytosine arabinoside and mitoxantrone therapy.

Journal: Cancer 19861015

Title: Inhibition of endogenous respiration in rat heart slices as a measure of mitoxantrone cardiac toxicity.

Journal: Oncology 19860101

Title: Early and delayed clinical cardiotoxicity of doxorubicin.

Journal: Cancer 19850615

Title: A randomized trial of doxorubicin, mitoxantrone and bisantrene in advanced breast cancer (a South West Oncology Group Study).

Journal: Investigational new drugs 19850101

Title: Fatal congestive heart failure following mitoxantrone treatment in two children previously treated with doxorubicin and cisplatin.

Journal: Cancer treatment reports 19830101

Title: Comparison of cardiotoxicity of two anthracenediones and doxorubicin in rats.

Journal: Toxicology letters 19820501

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Tags:70476-82-3 Molecular Formula|70476-82-3 MDL|70476-82-3 SMILES|70476-82-3 Mitoxantrone dihydrochloride