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72432-03-2,MFCD00867240
Catalog No.:AA00IC6Q

72432-03-2 | Miglitol

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1mg
98%
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$7.00   $5.00
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1g
98%
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$32.00   $22.00
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5g
98%
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$113.00   $79.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
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  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00IC6Q
Chemical Name:
Miglitol
CAS Number:
72432-03-2
Molecular Formula:
C8H17NO5
Molecular Weight:
207.2243
MDL Number:
MFCD00867240
SMILES:
OCCN1C[C@H](O)[C@H]([C@@H]([C@H]1CO)O)O
Properties
Computed Properties
 
Complexity:
179  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
4  
Heavy Atom Count:
14  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
5  
Rotatable Bond Count:
3  
XLogP3:
-2.6  

Downstream Synthesis Route

[1]CarbohydrateResearch,2016,vol.435,p.1-6

[2]JournalofNaturalProducts,2002,vol.65,p.198-202

[1]BioorganicandMedicinalChemistryLetters,2009,vol.19,p.5673-5674

87199-14-2    72432-03-2   
C15H21BNO6(1-) 

[1]RapidCommunicationsinMassSpectrometry,2016,p.155-161

Literature

Title: Effect of the addition of sitagliptin and miglitol on insulin-treated type 2 diabetes.

Journal: Diabetes therapy : research, treatment and education of diabetes and related disorders 20121201

Title: Intestinal alpha-glucosidase inhibitors: abdominal gas cysts.

Journal: Prescrire international 20120901

Title: Alpha-glucosidase inhibitors 2012 - cardiovascular considerations and trial evaluation.

Journal: Diabetes & vascular disease research 20120701

Title: Differential effects of α-glucosidase inhibitors on postprandial plasma glucose and lipid profile in patients with type 2 diabetes under control with insulin lispro mix 50/50.

Journal: Diabetes technology & therapeutics 20120701

Title: In vitro cytotoxic, antioxidative and alpha-glucosidase inhibitory potential of a herbal mixture comprised of Allium sativum and Lagerstroemia speciosa.

Journal: European review for medical and pharmacological sciences 20120701

Title: Nutrient detection by incretin hormone secreting cells.

Journal: Physiology & behavior 20120606

Title: Miglitol administered before breakfast increased plasma active glucagon-like peptide-1 (GLP-1) levels after lunch in patients with type 2 diabetes treated with sitagliptin.

Journal: Acta diabetologica 20120601

Title: Effect of miglitol as an add-on to bolus insulin on postprandial glycemic excursions in type 2 diabetes patients assessed by continuous glucose monitoring.

Journal: Diabetes technology & therapeutics 20120501

Title: Anorexigenic effects of miglitol in concert with the alterations of gut hormone secretion and gastric emptying in healthy subjects.

Journal: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20120401

Title: Newer insights into the drug delivery approaches of α-glucosidase inhibitors.

Journal: Expert opinion on drug delivery 20120401

Title: Reappraisal of metformin efficacy in the treatment of type 2 diabetes: a meta-analysis of randomised controlled trials.

Journal: PLoS medicine 20120401

Title: Comparisons of the effects of 12-week administration of miglitol and voglibose on the responses of plasma incretins after a mixed meal in Japanese type 2 diabetic patients.

Journal: Diabetes, obesity & metabolism 20120301

Title: Effect of 3-month repeated administration of miglitol on vascular endothelial function in patients with diabetes mellitus and coronary artery disease.

Journal: The American journal of cardiology 20120101

Title: Preventive pharmacotherapy in type 2 diabetes mellitus.

Journal: Indian journal of endocrinology and metabolism 20120101

Title: Effect of the α-glucosidase inhibitor miglitol on the glucose profile in Japanese type 2 diabetic patients receiving multiple daily insulin injections.

Journal: Endocrine journal 20120101

Title: Performance scores in general practice: a comparison between the clinical versus medication-based approach to identify target populations.

Journal: PloS one 20120101

Title: Efficacy of various antidiabetic agents as add-on treatments to metformin in type 2 diabetes mellitus: systematic review and meta-analysis.

Journal: ISRN endocrinology 20120101

Title: The management of type 2 diabetic patients with hypoglycaemic agents.

Journal: ISRN endocrinology 20120101

Title: Pharmacological approaches to the management of type 2 diabetes in fasting adults during Ramadan.

Journal: Diabetes, metabolic syndrome and obesity : targets and therapy 20120101

Title: Polymer-based delivery of glucagon-like Peptide-1 for the treatment of diabetes.

Journal: ISRN endocrinology 20120101

Title: Successful treatment of reactive hypoglycemia secondary to late dumping syndrome using miglitol.

Journal: Internal medicine (Tokyo, Japan) 20120101

Title: Miglitol, an anti-diabetic drug, inhibits oxidative stress-induced apoptosis and mitochondrial ROS over-production in endothelial cells by enhancement of AMP-activated protein kinase.

Journal: Journal of pharmacological sciences 20120101

Title: Study of the inhibition of two human maltase-glucoamylases catalytic domains by different α-glucosidase inhibitors.

Journal: Carbohydrate research 20111213

Title: Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).

Journal: PLoS computational biology 20111201

Title: Treatment with the α-glucosidase inhibitor miglitol from the preonset stage in Otsuka Long-Evans Tokushima Fatty rats improves glycemic control and reduces the expression of inflammatory cytokine genes in peripheral leukocytes.

Journal: Metabolism: clinical and experimental 20111101

Title: Both stimulation of GLP-1 receptors and inhibition of glycogenolysis additively contribute to a protective effect of oral miglitol against ischaemia-reperfusion injury in rabbits.

Journal: British journal of pharmacology 20110901

Title: Iminosugars as therapeutic agents: recent advances and promising trends.

Journal: Future medicinal chemistry 20110901

Title: Mapping the intestinal alpha-glucogenic enzyme specificities of starch digesting maltase-glucoamylase and sucrase-isomaltase.

Journal: Bioorganic & medicinal chemistry 20110701

Title: Targeting enteral endocrinal L-cells with dietary carbohydrates, by increasing the availability of miglitol in the intestinal lumen, leads to multi-fold enhancement of plasma glucagon-like peptide-1 levels in non-diabetic canines.

Journal: Drug development and industrial pharmacy 20110501

Title: Primary language, income and the intensification of anti-glycemic medications in managed care: the (TRIAD) study.

Journal: Journal of general internal medicine 20110501

Title: Risk of bladder cancer among diabetic patients treated with pioglitazone: interim report of a longitudinal cohort study.

Journal: Diabetes care 20110401

Title: Cohort study of pioglitazone and cancer incidence in patients with diabetes.

Journal: Diabetes care 20110401

Title: Ultra-performance liquid chromatography electrospray ionization-tandem mass spectrometry method for the estimation of miglitol in human plasma using metformin as the internal standard.

Journal: Drug testing and analysis 20110401

Title: Quercetin attenuates fasting and postprandial hyperglycemia in animal models of diabetes mellitus.

Journal: Nutrition research and practice 20110401

Title: Efficacy of combined use of miglitol in Type 2 diabetes patients receiving insulin therapy-placebo-controlled double-blind comparative study.

Journal: Acta diabetologica 20110301

Title: Evaluation of the efficacy and tolerability of miglitol in Chinese patients with type 2 diabetes mellitus inadequately controlled by diet and sulfonylureas.

Journal: Acta diabetologica 20110301

Title: Serum and urine cystatin C are poor biomarkers for acute kidney injury and renal replacement therapy.

Journal: Intensive care medicine 20110301

Title: Comparing the efficacy of α-glucosidase inhibitors in suppressing postprandial hyperglycemia using continuous glucose monitoring: a pilot study-the MAJOR study.

Journal: Diabetes technology & therapeutics 20110301

Title: Glycosylation failure extends to glycoproteins in gestational diabetes mellitus: evidence from reduced α2-6 sialylation and impaired immunomodulatory activities of pregnancy-related glycodelin-A.

Journal: Diabetes 20110301

Title: Elevated serum levels of interleukin-18 in patients with overt diabetic nephropathy: effects of miglitol.

Journal: Clinical and experimental nephrology 20110201

Title: The role of alpha-glucosidase in germinating barley grains.

Journal: Plant physiology 20110201

Title: The synthesis and biological evaluation of 1-C-alkyl-L-arabinoiminofuranoses, a novel class of α-glucosidase inhibitors.

Journal: Bioorganic & medicinal chemistry letters 20110115

Title: Antidiabetic Indian plants: a good source of potent amylase inhibitors.

Journal: Evidence-based complementary and alternative medicine : eCAM 20110101

Title: Advances in the treatment of type 2 diabetes mellitus.

Journal: American journal of therapeutics 20110101

Title: Evaluation of traditional Indian antidiabetic medicinal plants for human pancreatic amylase inhibitory effect in vitro.

Journal: Evidence-based complementary and alternative medicine : eCAM 20110101

Title: Potent α-amylase inhibitory activity of Indian Ayurvedic medicinal plants.

Journal: BMC complementary and alternative medicine 20110101

Title: A proprietary alpha-amylase inhibitor from white bean (Phaseolus vulgaris): a review of clinical studies on weight loss and glycemic control.

Journal: Nutrition journal 20110101

Title: Sitagliptin is effective and safe as add-on to insulin in patients with absolute insulin deficiency: a case series.

Journal: Journal of medical case reports 20110101

Title: In vitro and in vivo anti-hyperglycemic effects of Omija (Schizandra chinensis) fruit.

Journal: International journal of molecular sciences 20110101

Title: Cinnamon extract inhibits α-glucosidase activity and dampens postprandial glucose excursion in diabetic rats.

Journal: Nutrition & metabolism 20110101

Title: Antihyperglycemic effect of the alcoholic seed extract of Swietenia macrophylla on streptozotocin-diabetic rats.

Journal: Pharmacognosy research 20110101

Title: Effects of onion (Allium cepa L.) extract administration on intestinal α-glucosidases activities and spikes in postprandial blood glucose levels in SD rats model.

Journal: International journal of molecular sciences 20110101

Title: Effects of miglitol in platelet-derived microparticle, adiponectin, and selectin level in patients with type 2 diabetes mellitus.

Journal: International journal of general medicine 20110101

Title: Effects of miglitol in combination with intensive insulin therapy on blood glucose control with special reference to incretin responses in type 1 diabetes mellitus.

Journal: Endocrine journal 20110101

Title: Effects of calcium channel blockers on glucose tolerance, inflammatory state, and circulating progenitor cells in non-diabetic patients with essential hypertension: a comparative study between azelnidipine and amlodipine on glucose tolerance and endothelial function--a crossover trial (AGENT).

Journal: Cardiovascular diabetology 20110101

Title: A review of methods used in assessing non-serious adverse drug events in observational studies among type 2 diabetes mellitus patients.

Journal: Health and quality of life outcomes 20110101

Title: Medicinal chemistry of novel anti-diabetic drugs.

Journal: The open medicinal chemistry journal 20110101

Title: Synthesis and α-glucosidase inhibitory mechanisms of bis(2,3-dibromo-4,5-dihydroxybenzyl) ether, a potential marine bromophenol α-glucosidase inhibitor.

Journal: Marine drugs 20110101

Title: Management of diabetes across the course of disease: minimizing obesity-associated complications.

Journal: Diabetes, metabolic syndrome and obesity : targets and therapy 20110101

Title: A pilot study of the efficacy of miglitol and sitagliptin for type 2 diabetes with a continuous glucose monitoring system and incretin-related markers.

Journal: Cardiovascular diabetology 20110101

Title: The α-glucosidase inhibitor miglitol decreases glucose fluctuations and inflammatory cytokine gene expression in peripheral leukocytes of Japanese patients with type 2 diabetes mellitus.

Journal: Metabolism: clinical and experimental 20101201

Title: Hypoglycemic effects of Welsh onion in an animal model of diabetes mellitus.

Journal: Nutrition research and practice 20101201

Title: Probing the active-site requirements of human intestinal N-terminal maltase-glucoamylase: Synthesis and enzyme inhibitory activities of a six-membered ring nitrogen analogue of kotalanol and its de-O-sulfonated derivative.

Journal: Bioorganic & medicinal chemistry 20101115

Title: Acute pancreatitis in type 2 diabetes treated with exenatide or sitagliptin: a retrospective observational pharmacy claims analysis.

Journal: Diabetes care 20101101

Title: Changes in α-glucosidase activities along the jejunal-ileal axis of normal rats by the α-glucosidase inhibitor miglitol.

Journal: Metabolism: clinical and experimental 20101001

Title: Amplification of the inhibitory activity and reversal of the selectivity of miglitol by C(2')-monofluorination.

Journal: Archiv der Pharmazie 20101001

Title: The effect of oral antidiabetic agents on A1C levels: a systematic review and meta-analysis.

Journal: Diabetes care 20100801

Title: Recommendations for management of diabetes during Ramadan: update 2010.

Journal: Diabetes care 20100801

Title: Single administration of alpha-glucosidase inhibitors on endothelial function and incretin secretion in diabetic patients with coronary artery disease - Juntendo University trial: effects of miglitol on endothelial vascular reactivity in type 2 diabetic patients with coronary heart disease (J-MACH) -.

Journal: Circulation journal : official journal of the Japanese Circulation Society 20100701

Title: Sitagliptin: review of preclinical and clinical data regarding incidence of pancreatitis.

Journal: International journal of clinical practice 20100601

Title: Drug utilization of oral hypoglycemic agents in a university teaching hospital in India.

Journal: Journal of clinical pharmacy and therapeutics 20100601

Title: Computational identification of uncharacterized cruzain binding sites.

Journal: PLoS neglected tropical diseases 20100501

Title: A case of insulinoma following total gastrectomy--effects of an alpha-glucosidase inhibitor on suppressing GIP and GLP-1 elevations.

Journal: Diabetes research and clinical practice 20100401

Title: Disordered eating behavior in individuals with diabetes: importance of context, evaluation, and classification.

Journal: Diabetes care 20100301

Title: Glucose supply and insulin demand dynamics of antidiabetic agents.

Journal: Journal of diabetes science and technology 20100301

Title: Development and validation of HPLC-UV-MS method for the control of four anti-diabetic drugs in suspected counterfeit products.

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20100301

Title: Dual-action lipophilic iminosugar improves glycemic control in obese rodents by reduction of visceral glycosphingolipids and buffering of carbohydrate assimilation.

Journal: Journal of medicinal chemistry 20100128

Title: New glucosidase inhibitors from an ayurvedic herbal treatment for type 2 diabetes: structures and inhibition of human intestinal maltase-glucoamylase with compounds from Salacia reticulata.

Journal: Biochemistry 20100126

Title: Glycosidase inhibition: assessing mimicry of the transition state.

Journal: Organic & biomolecular chemistry 20100121

Title: Aspects of insulin treatment.

Journal: Diabetes care 20100101

Title: Type 2 diabetes: postprandial hyperglycemia and increased cardiovascular risk.

Journal: Vascular health and risk management 20100101

Title: Effects of miglitol, sitagliptin or their combination on plasma glucose, insulin and incretin levels in non-diabetic men.

Journal: Endocrine journal 20100101

Title: Effects of pre-meal versus post-meal administration of miglitol on plasma glucagon-like peptide-1 and glucosedependent insulinotropic polypeptide levels in healthy men.

Journal: Endocrine journal 20100101

Title: Comparison of adverse gastrointestinal effects of acarbose and miglitol in healthy men: a crossover study.

Journal: Internal medicine (Tokyo, Japan) 20100101

Title: Pneumatosis cystoides intestinalis induced by the α-glucosidase inhibitor miglitol.

Journal: Internal medicine (Tokyo, Japan) 20100101

Title: Antioxidant rich grape pomace extract suppresses postprandial hyperglycemia in diabetic mice by specifically inhibiting alpha-glucosidase.

Journal: Nutrition & metabolism 20100101

Title: Reduced expression of β2 integrin genes in rat peripheral leukocytes by inhibiting postprandial hyperglycemia.

Journal: Bioscience, biotechnology, and biochemistry 20100101

Title: The role of lipid and carbohydrate digestive enzyme inhibitors in the management of obesity: a review of current and emerging therapeutic agents.

Journal: Diabetes, metabolic syndrome and obesity : targets and therapy 20100101

Title: Stability-Indicating RP-HPLC Method for Estimation of Miglitol in Bulk and Tablets.

Journal: Indian journal of pharmaceutical sciences 20100101

Title: The alpha-glucosidase inhibitor miglitol delays the development of diabetes and dysfunctional insulin secretion in pancreatic beta-cells in OLETF rats.

Journal: European journal of pharmacology 20091210

Title: Design and evaluation of oral bioadhesive controlled release formulations of miglitol, intended for prolonged inhibition of intestinal alpha-glucosidases and enhancement of plasma glucagon like peptide-1 levels.

Journal: International journal of pharmaceutics 20091001

Title: Amplification of the inhibitory activity of miglitol by monofluorination.

Journal: Bioorganic & medicinal chemistry letters 20091001

Title: The alpha-glucosidase inhibitor miglitol suppresses postprandial hyperglycaemia and interleukin-1beta and tumour necrosis factor-alpha gene expression in rat peripheral leucocytes induced by intermittent sucrose loading.

Journal: The British journal of nutrition 20090701

Title: The alpha-glucosidase inhibitor miglitol decreases glucose fluctuations and gene expression of inflammatory cytokines induced by hyperglycemia in peripheral leukocytes.

Journal: Nutrition (Burbank, Los Angeles County, Calif.) 20090601

Title: Effect of miglitol, an alpha-glucosidase inhibitor, on atherogenic outcomes in balloon-injured diabetic rats.

Journal: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20090301

Title: Diabetes treatment.

Journal: Diabetes care 20090301

Title: Miglitol induces prolonged and enhanced glucagon-like peptide-1 and reduced gastric inhibitory polypeptide responses after ingestion of a mixed meal in Japanese Type 2 diabetic patients.

Journal: Diabetic medicine : a journal of the British Diabetic Association 20090201

Title: Rapid quantification of miglustat in human plasma and cerebrospinal fluid by liquid chromatography coupled with tandem mass spectrometry.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20090115

Title: Effect of insulin-unstimulated diabetic therapy with miglitol on serum cystatin C level and its clinical significance.

Journal: Diabetes research and clinical practice 20090101

Title: Postprandial hyperglycemia as an etiological factor in vascular failure.

Journal: Cardiovascular diabetology 20090101

Title: Effects of a low-carbohydrate diet on glycemic control in outpatients with severe type 2 diabetes.

Journal: Nutrition & metabolism 20090101

Title: Hypoglycemic herbs and their action mechanisms.

Journal: Chinese medicine 20090101

Title: Suppressive response of confections containing the extractive from leaves of Morus Alba on postprandial blood glucose and insulin in healthy human subjects.

Journal: Nutrition & metabolism 20090101

Title: A cardiologic approach to non-insulin antidiabetic pharmacotherapy in patients with heart disease.

Journal: Cardiovascular diabetology 20090101

Title: Design, statistical analysis and sample size calculation of a phase IIb/III study of linagliptin versus voglibose and placebo.

Journal: Trials 20090101

Title: Drugs associated with more suicidal ideations are also associated with more suicide attempts.

Journal: PloS one 20090101

Title: Pneumatosis cystoides intestinalis of the ascending colon related to acarbose treatment: a case report.

Journal: Journal of medical case reports 20090101

Title: Acute metabolic responses to a high-carbohydrate meal in outpatients with type 2 diabetes treated with a low-carbohydrate diet: a crossover meal tolerance study.

Journal: Nutrition & metabolism 20090101

Title: Postprandial hypoglycemic effect of mulberry leaf in Goto-Kakizaki rats and counterpart control Wistar rats.

Journal: Nutrition research and practice 20090101

Title: Management of obesity, insulin resistance and type 2 diabetes in children: consensus and controversy.

Journal: Diabetes, metabolic syndrome and obesity : targets and therapy 20090101

Title: Alpha-glucosidase inhibitors in the early treatment of type 2 diabetes.

Journal: Vascular health and risk management 20081201

Title: Synthesis of iminoalditol analogues of galactofuranosides and their activities against glycosidases.

Journal: Carbohydrate research 20081124

Title: Miglitol suppresses the postprandial increase in interleukin 6 and enhances active glucagon-like peptide 1 secretion in viscerally obese subjects.

Journal: Metabolism: clinical and experimental 20080901

Title: Comparison of pre- vs. postmeal administration of miglitol for 3 months in type 2 diabetic patients.

Journal: Diabetes, obesity & metabolism 20080901

Title: In vitro inhibition of glycogen-degrading enzymes and glycosidases by six-membered sugar mimics and their evaluation in cell cultures.

Journal: Bioorganic & medicinal chemistry 20080801

Title: Alpha-glucosidase-like activity detected in a siboglinid polychaete, Oligobrachia mashikoi.

Journal: Zoological science 20080401

Title: Effect of butanol fraction from Cassia tora L. seeds on glycemic control and insulin secretion in diabetic rats.

Journal: Nutrition research and practice 20080101

Title: Divided-dose administration of miglitol just before and 15 minutes after the start of a meal smoothes postprandial plasma glucose excursions and serum insulin responses in healthy men.

Journal: Endocrine journal 20071201

Title: [In-vitro study of the drug interactions between Miglitol, an alpha-glucosidase inhibitor, and adsorbents].

Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20071201

Title: Miglitol increases the adiponectin level and decreases urinary albumin excretion in patients with type 2 diabetes mellitus.

Journal: Metabolism: clinical and experimental 20071101

Title: [Adverse effects of alpha-glucosidase inhibitors].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20071028

Title: Administration of miglitol until 30 min after the start of a meal is effective in type 2 diabetic patients.

Journal: Diabetes research and clinical practice 20071001

Title: Effects of miglitol, an alpha-glucosidase inhibitor, on glycaemic status and histopathological changes in islets in non-obese, non-insulin-dependent diabetic Goto-Kakizaki rats.

Journal: The British journal of nutrition 20071001

Title: Optimizing combination treatment in the management of type 2 diabetes.

Journal: Vascular health and risk management 20071001

Title: Swings in blood glucose levels accelerate atherogenesis in apolipoprotein E-deficient mice.

Journal: Biochemical and biophysical research communications 20070706

Title: Evaluation of the efficacy, safety and tolerability of miglitol in adult Indian patients with uncomplicated type 2 diabetes mellitus.

Journal: Journal of the Indian Medical Association 20070601

Title: Indian herbs and herbal drugs used for the treatment of diabetes.

Journal: Journal of clinical biochemistry and nutrition 20070501

Title: Imino sugars are potent agonists of the human glucose sensor SGLT3.

Journal: Molecular pharmacology 20070201

Title: Determination of miglitol in human plasma by liquid chromatography/tandem mass spectrometry.

Journal: Rapid communications in mass spectrometry : RCM 20070101

Title: [Iminosugars: current and future therapeutic applications].

Journal: Annales pharmaceutiques francaises 20070101

Title: Thioglycosides as inhibitors of hSGLT1 and hSGLT2: potential therapeutic agents for the control of hyperglycemia in diabetes.

Journal: International journal of medical sciences 20070101

Title: The genus Gluconobacter oxydans: comprehensive overview of biochemistry and biotechnological applications.

Journal: Critical reviews in biotechnology 20070101

Title: Hypoglycemic and hypolipidemic effects of Saururus chinensis Baill in streptozotocin-induced diabetic rats.

Journal: Nutrition research and practice 20070101

Title: Inhibition of recombinant human maltase glucoamylase by salacinol and derivatives.

Journal: The FEBS journal 20060601

Title: Oxidative stress in type 2 diabetes: the role of fasting and postprandial glycaemia.

Journal: International journal of clinical practice 20060301

Title: [Pharmacokinetic, pharmacological, and clinical profile of miglitol (SEIBULE), a novel alpha-glucosidase inhibitor].

Journal: Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20060301

Title: Liquid chromatographic tandem mass spectrometry method for the quantification of miglitol in human plasma.

Journal: Arzneimittel-Forschung 20060101

Title: The anti-diabetic drug miglitol is protective against anginal ischaemia through a mechanism independent of regional myocardial blood flow in the dog.

Journal: Clinical and experimental pharmacology & physiology 20051001

Title: Prediction of genotoxicity of chemical compounds by statistical learning methods.

Journal: Chemical research in toxicology 20050601

Title: Alpha-glucosidase inhibitors for type 2 diabetes mellitus.

Journal: The Cochrane database of systematic reviews 20050418

Title: Alpha-glucosidase inhibitors for patients with type 2 diabetes: results from a Cochrane systematic review and meta-analysis.

Journal: Diabetes care 20050101

Title: Cardiovascular risk factors associated with insulin resistance: effects of oral antidiabetic agents.

Journal: American journal of cardiovascular drugs : drugs, devices, and other interventions 20050101

Title: C-glycosides and aza-C-glycosides as potential glycosidase and glycosyltransferase inhibitors.

Journal: Current topics in medicinal chemistry 20050101

Title: Synthesis and glycosidase inhibitory activity of new hexa-substituted C8-glycomimetics.

Journal: Beilstein journal of organic chemistry 20050101

Title: Antidiabetic drug miglitol inhibits myocardial apoptosis involving decreased hydroxyl radical production and Bax expression in an ischaemia/reperfusion rabbit heart.

Journal: British journal of pharmacology 20040701

Title: The effects of oral anti-hyperglycaemic medications on serum lipid profiles in patients with type 2 diabetes.

Journal: Diabetes, obesity & metabolism 20040301

Title: [Usefulness of miglitol in patients with diabetes mellitus type 2 and insufficient control of the blood glucose].

Journal: Revista clinica espanola 20040101

Title: [Continuation 50. Type 2 diabetes: possibilities and limitations of pharmacological therapy].

Journal: MMW Fortschritte der Medizin 20031218

Title: [Therapy decision based on the glucose triad. Drug treatment of type 2 diabetes].

Journal: MMW Fortschritte der Medizin 20030227

Title: Is there a role for alpha-glucosidase inhibitors in the prevention of type 2 diabetes mellitus?

Journal: Drugs 20030101

Title: Biochemistry and biotechnological applications of Gluconobacter strains.

Journal: Applied microbiology and biotechnology 20021101

Title: Therapeutic options for the management of type 2 diabetes mellitus.

Journal: The American journal of managed care 20021101

Title: HbA(1c) and glycemic profile, basal- and post-treatment with Miglitol, in an area with a Mediterranean diet.

Journal: Diabetes care 20021001

Title: The effects of miglitol on glucagon-like peptide-1 secretion and appetite sensations in obese type 2 diabetics.

Journal: Diabetes, obesity & metabolism 20020901

Title: Dose-dependent efficacy of miglitol, an alpha-glucosidase inhibitor, in type 2 diabetic patients on diet alone: results of a 24-week double-blind placebo-controlled study.

Journal: Diabetes, nutrition & metabolism 20020601

Title: [Postprandial hyperglycemia. II. Pharmacological approaches].

Journal: Revue medicale de Liege 20020401

Title: Control of post-prandial hyperglycemia--an essential part of good diabetes treatment and prevention of cardiovascular complications.

Journal: Nutrition, metabolism, and cardiovascular diseases : NMCD 20020401

Title: New sugar-mimic alkaloids from the pods of Angylocalyx pynaertii.

Journal: Journal of natural products 20020201

Title: Potential pharmacokinetics interference between alpha-glucosidase inhibitors and other oral antidiabetic agents.

Journal: Diabetes care 20020101

Title: [Reducing postprandial glucose levels. Glucosidase antagonists].

Journal: Pharmazie in unserer Zeit 20020101

Title: Postprandial hyperglycemia in patients with type 2 diabetes mellitus.

Journal: Treatments in endocrinology 20020101

Title: Critical Importance of alpha-glucosidase contained in rice kernel for alcohol fermentation of rice polish.

Journal: Journal of bioscience and bioengineering 20020101

Title: Miglitol combined with metformin improves glycaemic control in type 2 diabetes.

Journal: Diabetes, obesity & metabolism 20011001

Title: Pathophysiologic mechanisms of postprandial hyperglycemia.

Journal: The American journal of cardiology 20010920

Title: Combination of miglitol, an anti-diabetic drug, and nicorandil markedly reduces myocardial infarct size through opening the mitochondrial K(ATP) channels in rabbits.

Journal: British journal of pharmacology 20010801

Title: [The alpha-glucosidase inhibitor miglitol for the treatment of type 2 diabetes mellitus in the doctor's office].

Journal: Fortschritte der Medizin. Originalien 20010719

Title: A new era in type 2 diabetes mellitus treatment?

Journal: The American journal of medicine 20010701

Title: The synergistic effect of miglitol plus metformin combination therapy in the treatment of type 2 diabetes.

Journal: Diabetes care 20010601

Title: [Current and future aspects of oral antidiabetic agents in type 2 diabetes].

Journal: Vnitrni lekarstvi 20010501

Title: [Alpha-glucosidase inhibitor in type 2 diabetic patients. Metabolism and body weight are favorably modified].

Journal: MMW Fortschritte der Medizin 20010426

Title: Improved glycaemic control with miglitol in inadequately-controlled type 2 diabetics.

Journal: Diabetes research and clinical practice 20010301

Title: Oral hypoglycemic agents: insulin secretagogues, alpha-glucosidase inhibitors and insulin sensitizers.

Journal: Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 20010101

Title: Fukaya, N., et al., The alpha-glucosidase inhibitor miglitol delays the development of diabetes and dysfunctional insulin secretion in pancreatic beta-cells in OLETF rats. Eur J Pharmacol, 2009. 624(1-3): p. 51-7.

Title: Hirata, A., et al., Effect of miglitol, an alpha-glucosidase inhibitor, on atherogenic outcomes in balloon-injured diabetic rats. Horm Metab Res, 2009. 41(3): p. 213-20.

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Tags:72432-03-2 Molecular Formula|72432-03-2 MDL|72432-03-2 SMILES|72432-03-2 Miglitol