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7327-87-9,MFCD00035271
Catalog No.:AA0039J1

7327-87-9 | Dihydralazine sulfate

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1mg
98%
in stock  
$25.00   $18.00
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5mg
98%
in stock  
$60.00   $42.00
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10mg
98%
in stock  
$82.00   $57.00
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25mg
98%
in stock  
$136.00   $96.00
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50mg
98%
in stock  
$232.00   $163.00
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100mg
98%
in stock  
$301.00   $211.00
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250mg
98%
in stock  
$507.00   $355.00
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1g
98%
in stock  
$1,218.00   $853.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA0039J1
Chemical Name:
Dihydralazine sulfate
CAS Number:
7327-87-9
Molecular Formula:
C8H12N6O4S
Molecular Weight:
288.2837
MDL Number:
MFCD00035271
SMILES:
OS(=O)(=O)O.NNc1nnc(c2c1cccc2)NN
Properties
Computed Properties
 
Complexity:
248  
Covalently-Bonded Unit Count:
2  
Heavy Atom Count:
19  
Hydrogen Bond Acceptor Count:
10  
Hydrogen Bond Donor Count:
6  
Rotatable Bond Count:
2  

Downstream Synthesis Route

[1]JournaloftheIndianChemicalSociety,1991,vol.68,p.402-403

7327-87-9   
5-nitro-2-furaldehydediacetate 
 
C18H12N8O6 

[1]ScientiaPharmaceutica,1995,vol.63,p.29-35

Literature

Title: The differential effects of recombinant brain natriuretic peptide, nitroglycerine and dihydralazine on systemic oxygen delivery and gastric mucosal microvascular oxygenation in dogs.

Journal: Anaesthesia 20120501

Title: Long-term efficacy and tolerability of a fixed-dose combination of antihypertensive agents: an open-label surveillance study in China.

Journal: Clinical drug investigation 20111101

Title: Flow-injection chemiluminescence determination of dihydralazine sulfate in serum using luminol and diperiodatocuprate (III) system.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20100101

Title: Effects of dihydralazine on renal water and aquaporin-2 excretion in humans.

Journal: Scandinavian journal of clinical and laboratory investigation 20090101

Title: Regression of glomerulosclerosis in subtotally nephrectomized rats: effects of monotherapy with losartan, spironolactone, and their combination.

Journal: American journal of physiology. Renal physiology 20080701

Title: Chemiluminescence investigation of carbon dioxide-enhanced oxidation of dihydralazine sulfate by peroxynitrite and its application to pharmaceutical analysis.

Journal: Analytica chimica acta 20080602

Title: Maternal and fetal hemodynamic effects induced by nitric oxide donors and plasma volume expansion in pregnancies with gestational hypertension complicated by intrauterine growth restriction with absent end-diastolic flow in the umbilical artery.

Journal: Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology 20080101

Title: Progress curve analysis of CYP1A2 inhibition: a more informative approach to the assessment of mechanism-based inactivation?

Journal: Drug metabolism and disposition: the biological fate of chemicals 20071201

Title: Method development for dihydralazine with HPLC-MS/MS--an old but tricky substance in human plasma.

Journal: Journal of pharmaceutical and biomedical analysis 20070117

Title: Antihypertensive therapy in patients with pre-eclampsia: A prospective randomised multicentre study comparing dihydralazine with urapidil.

Journal: European journal of obstetrics, gynecology, and reproductive biology 20060801

Title: Dihydralazine treatment limits liver injury after hemorrhagic shock in rats.

Journal: Critical care medicine 20060301

Title: Changes in metabolism and blood flow following catecholamine stimulation in the synovial membrane measured with microdialysis.

Journal: Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA 20060201

Title: Morbidity and development in childhood of infants born after temporising treatment of early onset pre-eclampsia.

Journal: BJOG : an international journal of obstetrics and gynaecology 20050701

Title: Hypertension in children with chronic renal failure.

Journal: The Turkish journal of pediatrics 20050101

Title: Site-specific 99mTc-labeling of antibody using dihydrazinophthalazine (DHZ) conjugation to Fc region of heavy chain.

Journal: Archives of pharmacal research 20040901

Title: [Determination of five components in compound hypotensive tablet by HPLC].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20040801

Title: The impact of maternal plasma volume expansion and antihypertensive treatment with intravenous dihydralazine on fetal and maternal hemodynamics during pre-eclampsia: a clinical, echo-Doppler and viscometric study.

Journal: Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology 20040401

Title: Flow injection chemiluminescence determination of dihydralazine sulphate based on permanganate oxidation sensitized by rhodamine B.

Journal: Luminescence : the journal of biological and chemical luminescence 20040101

Title: [When hypertension becomes an emergency case: lower the blood pressure, but slowly!].

Journal: MMW Fortschritte der Medizin 20030529

Title: Myocyte loss in early left ventricular hypertrophy of experimental renovascular hypertension.

Journal: Virchows Archiv : an international journal of pathology 20030401

Title: [Reversible loss of vision in severe preeclampsia: case report and review of the literature].

Journal: Zeitschrift fur Geburtshilfe und Neonatologie 20030101

Title: Drug-induced lupus as a cause of relapsing inflammatory disease after renal transplantation.

Journal: Pediatric transplantation 20020801

Title: Immune-mediated drug-induced liver disease.

Journal: Clinics in liver disease 20020801

Title: [Effect of Urapidil in antihypertensive therapy of preeclampsia on newborns].

Journal: Zentralblatt fur Gynakologie 20010901

Title: Influence of metabolic activation on the induction of micronuclei by antihypertensive drugs in L929 cells.

Journal: Archives of toxicology 20010201

Title: Ketanserin for the treatment of preeclampsia.

Journal: Journal of perinatal medicine 20010101

Title: Additive effects of dihydralazine during enflurane or isoflurane hypotensive anaesthesia for spinal fusion.

Journal: Canadian journal of anaesthesia = Journal canadien d'anesthesie 19880501

Title: Comparative study on the short-term effects of angiotensin converting enzyme inhibitors (Lopirin, SQUIBB and Tensiomin), and dihydralazine in chronic cardiac failure.

Journal: Acta physiologica Hungarica 19880101

Title: [Liver lesions induced by dihydralazine and propranolol].

Journal: Zentralblatt fur allgemeine Pathologie u. pathologische Anatomie 19850101

Title: Vagally mediated bradycardiac effect of prazosin in anaesthetized rats.

Journal: European journal of pharmacology 19841015

Title: Mode of antihypertensive action of nitrendipine.

Journal: Journal of cardiovascular pharmacology 19840101

Title: Action of vasodilating drugs on small and large arteries of hypertensive patients.

Journal: Journal of cardiovascular pharmacology 19830101

Title: [Hypotensive anaesthesia in the oto-rhino-laryngological surgery using nitroglycerine (author's transl)].

Journal: Der Anaesthesist 19800501

Title: [Rare liver damage caused by an antihypertensive and anti-arrhythmic agents].

Journal: Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete 19800401

Title: Effects of acute hypotension and hypertension on serum TSH concentrations in male rats.

Journal: Acta physiologica Scandinavica 19791001

Title: [Treatment of essential hypertension with a combination of propranolol, spironolactone-thiabutazide and dihydralazine (author's transl)].

Journal: Deutsche medizinische Wochenschrift (1946) 19781020

Title: Bijvank SW, et al. Ketanserin versus dihydralazine for the treatment of severe hypertension in early-onset preeclampsia: a double blind randomized controlled trial. Eur J Obstet Gynecol Reprod Biol. 2015 Jun;189:106-11.

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Tags:7327-87-9 Molecular Formula|7327-87-9 MDL|7327-87-9 SMILES|7327-87-9 Dihydralazine sulfate