[1]Torrence,PaulF.;Kinjo,Jun-ei;Khamnei,Shahrzad;Greig,NigelH.[JournalofMedicinalChemistry,1993,vol.36,#5,p.529-537]
[1]Sujino;Sugimura[TetrahedronLetters,1994,vol.35,#12,p.1883-1886]
[1]Farina,Vittorio;Benigni,DanielA.[TetrahedronLetters,1988,vol.29,#11,p.1239-1242]
[1]Motawia,MohammedS.;Pedersen,ErikB.[LiebigsAnnalenderChemie,1990,#6,p.599-602]
[1]Johansen,Oddvar;Holan,George;Marcuccio,SebastianM.;Mau,AlbertW.-H.[AustralianJournalofChemistry,1991,vol.44,p.37-41]
Title: Evaluating the Role of Multidrug Resistance Protein 3 (MDR3) Inhibition in Predicting Drug-Induced Liver Injury Using 125 Pharmaceuticals.
Journal: Chemical research in toxicology 20170515
Title: Ionic derivatives of betulinic acid exhibit antiviral activity against herpes simplex virus type-2 (HSV-2), but not HIV-1 reverse transcriptase.
Journal: Bioorganic & medicinal chemistry letters 20150815
Title: Discovery of 2-pyridone derivatives as potent HIV-1 NNRTIs using molecular hybridization based on crystallographic overlays.
Journal: Bioorganic & medicinal chemistry 20140315
Title: Design, synthesis and biological evaluation of N2,N4-disubstituted-1,1,3-trioxo-2H,4H-pyrrolo[1,2-b][1,2,4,6]thiatriazine derivatives as HIV-1 NNRTIs.
Journal: Bioorganic & medicinal chemistry 20131115
Title: Towards new C6-rigid S-DABO HIV-1 reverse transcriptase inhibitors: synthesis, biological investigation and molecular modeling studies.
Journal: Bioorganic & medicinal chemistry 20131101
Title: Sulfation and biological activities of konjac glucomannan.
Journal: Carbohydrate polymers 20130515
Title: Biological interaction between Sasa senanensis Rehder leaf extract and toothpaste ingredients.
Journal: In vivo (Athens, Greece) 20130101
Title: Structure-based bioisosterism design, synthesis and biological evaluation of novel 1,2,4-triazin-6-ylthioacetamides as potent HIV-1 NNRTIs.
Journal: Bioorganic & medicinal chemistry letters 20121201
Title: Discovery of novel 2-(3-(2-chlorophenyl)pyrazin-2-ylthio)-N-arylacetamides as potent HIV-1 inhibitors using a structure-based bioisosterism approach.
Journal: Bioorganic & medicinal chemistry 20121201
Title: Structural modifications of 5,6-dihydroxypyrimidines with anti-HIV activity.
Journal: Bioorganic & medicinal chemistry letters 20121201
Title: The correlation between pain-related behaviour and spinal microgliosis in four distinct models of peripheral neuropathy.
Journal: European journal of pain (London, England) 20121101
Title: Inhibition of transmitter release and attenuation of anti-retroviral-associated and tibial nerve injury-related painful peripheral neuropathy by novel synthetic Ca2+ channel peptides.
Journal: The Journal of biological chemistry 20121012
Title: Arylazolyl(azinyl)thioacetanilides. Part 10: design, synthesis and biological evaluation of novel substituted imidazopyridinylthioacetanilides as potent HIV-1 inhibitors.
Journal: Bioorganic & medicinal chemistry 20120915
Title: Squalenoylation: a generic platform for nanoparticular drug delivery.
Journal: Journal of controlled release : official journal of the Controlled Release Society 20120720
Title: Design, synthesis, anti-HIV evaluation and molecular modeling of piperidine-linked amino-triazine derivatives as potent non-nucleoside reverse transcriptase inhibitors.
Journal: Bioorganic & medicinal chemistry 20120615
Title: Cytosine deoxyribonucleoside anti-HIV analogues: a small chemical substitution allows relevant activities.
Journal: International journal of antimicrobial agents 20120601
Title: p53 and mitochondrial DNA: their role in mitochondrial homeostasis and toxicity of antiretrovirals.
Journal: The American journal of pathology 20120601
Title: Mitochondrial gene replacement in human pluripotent stem cell-derived neural progenitors.
Journal: Gene therapy 20120501
Title: Synthesis and biological evaluation of piperidine-substituted triazine derivatives as HIV-1 non-nucleoside reverse transcriptase inhibitors.
Journal: European journal of medicinal chemistry 20120501
Title: Erythrocyte inosine triphosphatase activity is decreased in HIV-seropositive individuals.
Journal: PloS one 20120101
Title: Combination of probenecid-sulphadoxine-pyrimethamine for intermittent preventive treatment in pregnancy.
Journal: Malaria journal 20120101
Title: Strong antiviral activity of the new l-hydroxycytidine derivative, l-Hyd4FC, in HBV-infected human chimeric uPA/SCID mice.
Journal: Antiviral therapy 20120101
Title: Adverse drug reactions to antiretroviral therapy (ARVs): incidence, type and risk factors in Nigeria.
Journal: BMC clinical pharmacology 20120101
Title: Assessment of liver fibrosis and associated risk factors in HIV-infected individuals using transient elastography and serum biomarkers.
Journal: BMC gastroenterology 20120101
Title: Prevalence of Drug Resistance and Associated Mutations in a Population of HIV-1(+) Puerto Ricans: 2006-2010.
Journal: AIDS research and treatment 20120101
Title: Pan-pathway based interaction profiling of FDA-approved nucleoside and nucleobase analogs with enzymes of the human nucleotide metabolism.
Journal: PloS one 20120101
Title: Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
Journal: PLoS computational biology 20111201
Title: How much do antiretroviral drugs penetrate into the central nervous system?
Journal: Journal of medicine and life 20111114
Title: TNFα is involved in neuropathic pain induced by nucleoside reverse transcriptase inhibitor in rats.
Journal: Brain, behavior, and immunity 20111101
Title: Arylazolylthioacetanilide. Part 8: Design, synthesis and biological evaluation of novel 2-(2-(2,4-dichlorophenyl)-2H-1,2,4-triazol-3-ylthio)-N-arylacetamides as potent HIV-1 inhibitors.
Journal: European journal of medicinal chemistry 20111001
Title: Synthesis and structure-activity relationship of novel diarylpyrimidines with hydromethyl linker (CH(OH)-DAPYs) as HIV-1 NNRTIs.
Journal: Bioorganic & medicinal chemistry 20110901
Title: Current Nucleos(t)ide Analogue Therapy for Chronic Hepatitis B.
Journal: Gut and liver 20110901
Title: Role of Drp1, a key mitochondrial fission protein, in neuropathic pain.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20110803
Title: The base component of 3'-azido-2',3'-dideoxynucleosides influences resistance mutations selected in HIV-1 reverse transcriptase.
Journal: Antimicrobial agents and chemotherapy 20110801
Title: Synthesis of enantiomerically pure D- and L-bicyclo[3.1.0]hexenyl carbanucleosides and their antiviral evaluation.
Journal: Bioorganic & medicinal chemistry 20110701
Title: Global gene disruption in human cells to assign genes to phenotypes by deep sequencing.
Journal: Nature biotechnology 20110601
Title: The response of spinal microglia to chemotherapy-evoked painful peripheral neuropathies is distinct from that evoked by traumatic nerve injuries.
Journal: Neuroscience 20110310
Title: [The curative effects of different drugs on liver cell damage of rats induced by acute nickel carbonyl poisoning].
Journal: Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases 20110201
Title: K70Q adds high-level tenofovir resistance to 'Q151M complex' HIV reverse transcriptase through the enhanced discrimination mechanism.
Journal: PloS one 20110101
Title: Management of HIV-1 associated hepatitis in patients with acquired immunodeficiency syndrome: role of a successful control of viral replication.
Journal: AIDS research and therapy 20110101
Title: Timely HAART initiation may pave the way for a better viral control.
Journal: BMC infectious diseases 20110101
Title: Effect of reverse transcriptase inhibitors on LINE-1 and Ty1 reverse transcriptase activities and on LINE-1 retrotransposition.
Journal: BMC biochemistry 20110101
Title: Interspecies somatic cell nuclear transfer is dependent on compatible mitochondrial DNA and reprogramming factors.
Journal: PloS one 20110101
Title: Conformational alterations in the CD4 binding cavity of HIV-1 gp120 influencing gp120-CD4 interactions and fusogenicity of HIV-1 envelopes derived from brain and other tissues.
Journal: Retrovirology 20110101
Title: Human immunodeficiency virus endocrinopathy.
Journal: Indian journal of endocrinology and metabolism 20110101
Title: Nanomedicine as an emerging approach against intracellular pathogens.
Journal: International journal of nanomedicine 20110101
Title: Role of pyrimidine depletion in the mitochondrial cardiotoxicity of nucleoside analogue reverse transcriptase inhibitors.
Journal: Journal of acquired immune deficiency syndromes (1999) 20101215
Title: Resistance profiles of novel electrostatically constrained HIV-1 fusion inhibitors.
Journal: The Journal of biological chemistry 20101210
Title: A predictive ligand-based Bayesian model for human drug-induced liver injury.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20101201
Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.
Journal: Bioorganic & medicinal chemistry letters 20101101
Title: Semiparametric analysis of recurrent events: artificial censoring, truncation, pairwise estimation and inference.
Journal: Lifetime data analysis 20101001
Title: Pharmacogenomics of human ABC transporter ABCC11 (MRP8): potential risk of breast cancer and chemotherapy failure.
Journal: Anti-cancer agents in medicinal chemistry 20101001
Title: Alcohol consumption enhances antiretroviral painful peripheral neuropathy by mitochondrial mechanisms.
Journal: The European journal of neuroscience 20100901
Title: Characterization of HIV-1 resistance to a fusion inhibitor, N36, derived from the gp41 amino-terminal heptad repeat.
Journal: Antiviral research 20100801
Title: Changing patterns of cancer incidence in the early- and late-HAART periods: the Swiss HIV Cohort Study.
Journal: British journal of cancer 20100727
Title: New trends in nucleoside biotechnology.
Journal: Acta naturae 20100701
Title: Transport characteristics of mouse concentrative nucleoside transporter 1.
Journal: International journal of pharmaceutics 20100330
Title: Novel enzymatic function of DNA polymerase nu in translesion DNA synthesis past major groove DNA-peptide and DNA-DNA cross-links.
Journal: Chemical research in toxicology 20100315
Title: Mitochondrial dysfunction enhances the migration of vascular smooth muscles cells via suppression of Akt phosphorylation.
Journal: Biochimica et biophysica acta 20100301
Title: Transgenic cardiac-targeted overexpression of human thymidylate kinase.
Journal: Laboratory investigation; a journal of technical methods and pathology 20100301
Title: Elvucitabine data released at CROI.
Journal: AIDS patient care and STDs 20100301
Title: Risk of myocardial infarction in patients with HIV infection exposed to specific individual antiretroviral drugs from the 3 major drug classes: the data collection on adverse events of anti-HIV drugs (D:A:D) study.
Journal: The Journal of infectious diseases 20100201
Title: Synthesis of fluorescent nucleoside analogs as probes for 2'-deoxyribonucleoside kinases.
Journal: Bioorganic & medicinal chemistry letters 20100201
Title: Oral uridine supplementation antagonizes the peripheral neuropathy and encephalopathy induced by antiretroviral nucleoside analogues.
Journal: AIDS (London, England) 20100128
Title: DNA polymerase-beta is required for 1-methyl-4-phenylpyridinium-induced apoptotic death in neurons.
Journal: Apoptosis : an international journal on programmed cell death 20100101
Title: Only slight impact of predicted replicative capacity for therapy response prediction.
Journal: PloS one 20100101
Title: Expression and functional activity of nucleoside transporters in human choroid plexus.
Journal: Cerebrospinal fluid research 20100101
Title: Technology Development Through Pooling ARV Drug Patents: A Vision from China.
Journal: The open AIDS journal 20100101
Title: Abacavir/lamivudine combination in the treatment of HIV: a review.
Journal: Therapeutics and clinical risk management 20100101
Title: Raltegravir is a potent inhibitor of XMRV, a virus implicated in prostate cancer and chronic fatigue syndrome.
Journal: PloS one 20100101
Title: Increasing rates of obesity among HIV-infected persons during the HIV epidemic.
Journal: PloS one 20100101
Title: Pyrimidine deoxynucleoside and nucleoside reverse transcriptase inhibitor metabolism in the perfused heart and isolated mitochondria.
Journal: Antiviral therapy 20100101
Title: Dynamics of HIV-1 quasispecies during antiviral treatment dissected using ultra-deep pyrosequencing.
Journal: PloS one 20100101
Title: Viral decay kinetics in the highly active antiretroviral therapy-treated rhesus macaque model of AIDS.
Journal: PloS one 20100101
Title: Estimating the impact of plasma HIV-1 RNA reductions on heterosexual HIV-1 transmission risk.
Journal: PloS one 20100101
Title: Progress in antiretroviral drug delivery using nanotechnology.
Journal: International journal of nanomedicine 20100101
Title: Antiretroviral therapy optimisation without genotype resistance testing: a perspective on treatment history based models.
Journal: PloS one 20100101
Title: Antiadenoviral effects of N-chlorotaurine in vitro confirmed by quantitative polymerase chain reaction methods.
Journal: Clinical ophthalmology (Auckland, N.Z.) 20100101
Title: Proteochemometric modeling of the susceptibility of mutated variants of the HIV-1 virus to reverse transcriptase inhibitors.
Journal: PloS one 20100101
Title: Pharmacological treatment of painful HIV-associated sensory neuropathy: a systematic review and meta-analysis of randomised controlled trials.
Journal: PloS one 20100101
Title: Beyond the black box: drug- and device-associated hypersensitivity events.
Journal: Drug, healthcare and patient safety 20100101
Title: Zidovudine-induced myopathy: A study in Indian patients.
Journal: Journal of neurosciences in rural practice 20100101
Title: New and emerging agents in the management of lipodystrophy in HIV-infected patients.
Journal: HIV/AIDS (Auckland, N.Z.) 20100101
Title: The pharmacokinetics of valganciclovir prophylaxis in pediatric solid organ transplant patients at risk for Epstein-Barr virus disease.
Journal: Clinical pharmacology : advances and applications 20100101
Title: Palmitic Acid Is a Novel CD4 Fusion Inhibitor That Blocks HIV Entry and Infection.
Journal: AIDS research and human retroviruses 20091201
Title: Freeze-drying of squalenoylated nucleoside analogue nanoparticles.
Journal: International journal of pharmaceutics 20091103
Title: The in vitro and in vivo evaluation of ddC as a topical antiviral for ocular adenovirus infections.
Journal: Investigative ophthalmology & visual science 20091101
Title: The role of transporters in the pharmacokinetics of orally administered drugs.
Journal: Pharmaceutical research 20090901
Title: Anti-human immunodeficiency virus activity, cross-resistance, cytotoxicity, and intracellular pharmacology of the 3'-azido-2',3'-dideoxypurine nucleosides.
Journal: Antimicrobial agents and chemotherapy 20090901
Title: The history of antiretrovirals: key discoveries over the past 25 years.
Journal: Reviews in medical virology 20090901
Title: Human heart mitochondrial DNA is organized in complex catenated networks containing abundant four-way junctions and replication forks.
Journal: The Journal of biological chemistry 20090807
Title: Human immunodeficiency virus: 25 years of diagnostic and therapeutic strategies and their impact on hepatitis B and C virus.
Journal: Medical microbiology and immunology 20090801
Title: Cytotoxicological analysis of a gp120 binding aptamer with cross-clade human immunodeficiency virus type 1 entry inhibition properties: comparison to conventional antiretrovirals.
Journal: Antimicrobial agents and chemotherapy 20090701
Title: Assessment of mitochondrial toxicity by analysis of mitochondrial protein expression in mononuclear cells.
Journal: Cytometry. Part B, Clinical cytometry 20090501
Title: The transport of anti-HIV drugs across blood-CNS interfaces: summary of current knowledge and recommendations for further research.
Journal: Antiviral research 20090501
Title: Timing of initiation of antiretroviral therapy in AIDS-free HIV-1-infected patients: a collaborative analysis of 18 HIV cohort studies.
Journal: Lancet (London, England) 20090418
Title: Screening and monitoring antiretrovirals and antivirals in the serum of acquired immunodeficiency syndrome patients by micellar liquid chromatography.
Journal: Journal of chromatography. A 20090417
Title: Comparison of dorsal root ganglion gene expression in rat models of traumatic and HIV-associated neuropathic pain.
Journal: European journal of pain (London, England) 20090401
Title: Anti-HIV drugs: 25 compounds approved within 25 years after the discovery of HIV.
Journal: International journal of antimicrobial agents 20090401
Title: Facilitated mitochondrial import of antiviral and anticancer nucleoside drugs by human equilibrative nucleoside transporter-3.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20090401
Title: Human multidrug resistance protein 7 (ABCC10) is a resistance factor for nucleoside analogues and epothilone B.
Journal: Cancer research 20090101
Title: An analysis of enzyme kinetics data for mitochondrial DNA strand termination by nucleoside reverse transcription inhibitors.
Journal: PLoS computational biology 20090101
Title: Prescribing and using self-injectable antiretrovirals: how concordant are physician and patient perspectives?
Journal: AIDS research and therapy 20090101
Title: Effects of the K65R and K65R/M184V reverse transcriptase mutations in subtype C HIV on enzyme function and drug resistance.
Journal: Retrovirology 20090101
Title: Clinical evaluation of local ocular toxicity in candidate anti-adenoviral agents in vivo.
Journal: Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde 20090101
Title: Type I interferons and interferon regulatory factors regulate TNF-related apoptosis-inducing ligand (TRAIL) in HIV-1-infected macrophages.
Journal: PloS one 20090101
Title: The triple combination of tenofovir, emtricitabine and efavirenz shows synergistic anti-HIV-1 activity in vitro: a mechanism of action study.
Journal: Retrovirology 20090101
Title: Serial evolutionary networks of within-patient HIV-1 sequences reveal patterns of evolution of X4 strains.
Journal: BMC systems biology 20090101
Title: Host sequence motifs shared by HIV predict response to antiretroviral therapy.
Journal: BMC medical genomics 20090101
Title: Increased chemokine signaling in a model of HIV1-associated peripheral neuropathy.
Journal: Molecular pain 20090101
Title: Pharmacotherapy of pediatric and adolescent HIV infection.
Journal: Therapeutics and clinical risk management 20090101
Title: Drugs associated with more suicidal ideations are also associated with more suicide attempts.
Journal: PloS one 20090101
Title: German-Austrian recommendations for HIV1-therapy in pregnancy and in HIV1-exposed newborn, update 2008.
Journal: European journal of medical research 20090101
Title: Anticancer conjugates and cocktails based on methotrexate and nucleoside synergism.
Journal: Clinical medicine. Oncology 20090101
Title: New approaches in the management of chronic hepatitis B: role of tenofovir.
Journal: Infection and drug resistance 20090101
Title: Pharmacologic and nonpharmacologic options for the management of HIV infection during pregnancy.
Journal: HIV/AIDS (Auckland, N.Z.) 20090101
Title: Hepatitis C virus NS5B polymerase exhibits distinct nucleotide requirements for initiation and elongation.
Journal: The Journal of biological chemistry 20081205
Title: Notch1 is a frequent mutational target in chemically induced lymphoma in mouse.
Journal: International journal of cancer 20081201
Title: Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Journal: Journal of medicinal chemistry 20081113
Title: Update on antiviral treatment of adenoviral ocular infections.
Journal: American journal of ophthalmology 20081101
Title: Trends in the prescription of antiretroviral drugs and impact on plasma HIV-RNA measurements.
Journal: The Journal of antimicrobial chemotherapy 20081001
Title: Disease- and treatment-related predictors of hepatic mitochondrial dysfunction in chronic HIV infection assessed by non-invasive (13)C-methionine breath test diagnostic.
Journal: European journal of medical research 20080922
Title: Relevance of the organic cation transporters 1 and 2 for antiretroviral drug therapy in human immunodeficiency virus infection.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20080801
Title: In vivo reshaping the catalytic site of nucleoside 2'-deoxyribosyltransferase for dideoxy- and didehydronucleosides via a single amino acid substitution.
Journal: The Journal of biological chemistry 20080718
Title: Role of spinal serotonin 5-HT2A receptor in 2',3'-dideoxycytidine-induced neuropathic pain in the rat and the mouse.
Journal: Pain 20080701
Title: Neurologic disorders are prevalent in HIV-positive outpatients in the Asia-Pacific region.
Journal: Neurology 20080701
Title: [Drug-related neuropathies: analysis of the French Adverse Drug Reaction Database 1995-2005].
Journal: Presse medicale (Paris, France : 1983) 20080601
Title: High concentrations of stavudine impair fatty acid oxidation without depleting mitochondrial DNA in cultured rat hepatocytes.
Journal: Toxicology in vitro : an international journal published in association with BIBRA 20080601
Title: [Tenofovir DF in rescue regimens].
Journal: Enfermedades infecciosas y microbiologia clinica 20080601
Title: Structural studies of nucleoside analog and feedback inhibitor binding to Drosophila melanogaster multisubstrate deoxyribonucleoside kinase.
Journal: The FEBS journal 20080501
Title: Influence of mitochondrial DNA level on cellular energy metabolism: implications for mitochondrial diseases.
Journal: Journal of bioenergetics and biomembranes 20080401
Title: Increased mitochondrial DNA copy-number in CEM cells resistant to delayed toxicity of 2',3'-dideoxycytidine.
Journal: Biochemical pharmacology 20080315
Title: Transdermal penetration of zalcitabine, lamivudine and synthesised N-acyl lamivudine esters.
Journal: International journal of pharmaceutics 20080303
Title: S-adenosylmethionine prevents Mallory Denk body formation in drug-primed mice by inhibiting the epigenetic memory.
Journal: Hepatology (Baltimore, Md.) 20080201
Title: Cytokine genotype suggests a role for inflammation in nucleoside analog-associated sensory neuropathy (NRTI-SN) and predicts an individual's NRTI-SN risk.
Journal: AIDS research and human retroviruses 20080201
Title: Interaction of transient receptor potential vanilloid 4, integrin, and SRC tyrosine kinase in mechanical hyperalgesia.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20080130
Title: Adenosine 3',5'-cyclic monophosphate (cAMP)-dependent phosphoregulation of mitochondrial complex I is inhibited by nucleoside reverse transcriptase inhibitors.
Journal: Toxicology and applied pharmacology 20080101
Title: Alcohol-induced stress in painful alcoholic neuropathy.
Journal: The European journal of neuroscience 20080101
Title: Uridine supplementation antagonizes zidovudine-induced mitochondrial myopathy and hyperlactatemia in mice.
Journal: Arthritis and rheumatism 20080101
Title: The incidence of multidrug and full class resistance in HIV-1 infected patients is decreasing over time (2001-2006) in Portugal.
Journal: Retrovirology 20080101
Title: Identification of a novel resistance (E40F) and compensatory (K43E) substitution in HIV-1 reverse transcriptase.
Journal: Retrovirology 20080101
Title: Longitudinal microarray analysis of cell surface antigens on peripheral blood mononuclear cells from HIV+ individuals on highly active antiretroviral therapy.
Journal: Retrovirology 20080101
Title: Vascularization of the dorsal root ganglia and peripheral nerve of the mouse: implications for chemical-induced peripheral sensory neuropathies.
Journal: Molecular pain 20080101
Title: 2'-deoxy-4'-C-ethynyl-2-halo-adenosines active against drug-resistant human immunodeficiency virus type 1 variants.
Journal: The international journal of biochemistry & cell biology 20080101
Title: The risk of developing peripheral neuropathy induced by nucleoside reverse transcriptase inhibitors decreases over time: evidence from the Delta trial.
Journal: Antiviral therapy 20080101
Title: Prevalence of drug resistance and associated mutations in HIV-positive Puerto Ricans: sex variations.
Journal: Ethnicity & disease 20080101
Title: Small-scale immunopurification of cytochrome c oxidase for a high-throughput multiplexing analysis of enzyme activity and amount.
Journal: Biotechnology and applied biochemistry 20071201
Title: Sublethal concentrations of gemcitabine (2',2'-difluorodeoxycytidine) alter mitochondrial ultrastructure and function without reducing mitochondrial DNA content in BxPC-3 human pancreatic carcinoma cells.
Journal: Human & experimental toxicology 20071201
Title: Differential sensitivity of thick and thin fibers to HIV and therapy-induced neuropathy.
Journal: Autonomic neuroscience : basic & clinical 20071030
Title: Effects of apricitabine and other nucleoside reverse transcriptase inhibitors on replication of mitochondrial DNA in HepG2 cells.
Journal: Antiviral research 20071001
Title: Characterization of rodent models of HIV-gp120 and anti-retroviral-associated neuropathic pain.
Journal: Brain : a journal of neurology 20071001
Title: Inhibition of Mycobacterium tuberculosis, Mycobacterium bovis, and Mycobacterium avium by novel dideoxy nucleosides.
Journal: Journal of medicinal chemistry 20070920
Title: Anti-adenoviral effect of anti-HIV agents in vitro in serotypes inducing keratoconjunctivitis.
Journal: Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20070901
Title: Mutations at 65 and 70 within the context of a Q151M cluster in human immunodeficiency virus type 1 reverse transcriptase impact the susceptibility to the different nucleoside reverse transcriptase inhibitors in distinct ways.
Journal: Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 20070901
Title: The effect of the palmitoylethanolamide analogue, palmitoylallylamide (L-29) on pain behaviour in rodent models of neuropathy.
Journal: British journal of pharmacology 20070801
Title: Simian immunodeficiency virus infection induces severe loss of intestinal central memory T cells which impairs CD4+ T-cell restoration during antiretroviral therapy.
Journal: Journal of medical primatology 20070801
Title: The renaissance of fixed dose combinations: Combivir.
Journal: Therapeutics and clinical risk management 20070801
Title: More on the treatment-tropism relationship: the impact of prior antiretroviral treatment on HIV coreceptor tropism among subjects entering AIDS clinical trials group 175.
Journal: The Journal of infectious diseases 20070715
Title: CXCR4 chemokine receptor signaling mediates pain hypersensitivity in association with antiretroviral toxic neuropathy.
Journal: Brain, behavior, and immunity 20070701
Title: Testing antiretroviral drug efficacy in conventional mice infected with chimeric HIV-1.
Journal: AIDS (London, England) 20070511
Title: Determination of 19 antiretroviral agents in pharmaceuticals or suspected products with two methods using high-performance liquid chromatography.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070501
Title: Development and evaluation of an oligonucleotide ligation assay for detection of drug resistance-associated mutations in the human immunodeficiency virus type 2 pol gene.
Journal: Journal of clinical microbiology 20070501
Title: Oxidative stress and toxicity induced by the nucleoside reverse transcriptase inhibitor (NRTI)--2',3'-dideoxycytidine (ddC): relevance to HIV-dementia.
Journal: Experimental neurology 20070301
Title: Characterization of an HIV-1 group M variant that is distinct from the known subtypes.
Journal: AIDS research and human retroviruses 20070301
Title: Regulated mitochondrial DNA replication during oocyte maturation is essential for successful porcine embryonic development.
Journal: Biology of reproduction 20070201
Title: Modulation of human BCRP (ABCG2) activity by anti-HIV drugs.
Journal: The Journal of antimicrobial chemotherapy 20070201
Title: The triphosphate of beta-D-4'-C-ethynyl-2',3'-dideoxycytidine is the preferred enantiomer substrate for HIV reverse transcriptase.
Journal: Bioorganic & medicinal chemistry 20070101
Title: Uridine supplementation antagonizes zalcitabine-induced microvesicular steatohepatitis in mice.
Journal: Hepatology (Baltimore, Md.) 20070101
Title: A dominant-negative form of the major human abasic endonuclease enhances cellular sensitivity to laboratory and clinical DNA-damaging agents.
Journal: Molecular cancer research : MCR 20070101
Title: Baseline resistance to nucleoside reverse transcriptase inhibitors fails to predict virologic response to combination therapy in children (PACTG 338).
Journal: AIDS research and therapy 20070101
Title: Mechanically-evoked C-fiber activity in painful alcohol and AIDS therapy neuropathy in the rat.
Journal: Molecular pain 20070101
Title: The AIDS and Cancer Specimen Resource: role in HIV/AIDS scientific discovery.
Journal: Infectious agents and cancer 20070101
Title: Dideoxynucleoside HIV reverse transcriptase inhibitors and drug-related hepatotoxicity: a case report.
Journal: Journal of medical case reports 20070101
Title: Relationship of mitochondrial DNA depletion and respiratory chain activity in preadipocytes treated with nucleoside reverse transcriptase inhibitors.
Journal: Antiviral therapy 20070101
Title: Development of a sensitive and specific liquid chromatography/mass spectrometry method for the determination of tenofovir in human plasma.
Journal: Rapid communications in mass spectrometry : RCM 20070101
Title: AIDS in the Third World: how to stop the HIV infection?
Journal: Verhandelingen - Koninklijke Academie voor Geneeskunde van Belgie 20070101
Title: Anti-HIV drugs.
Journal: Verhandelingen - Koninklijke Academie voor Geneeskunde van Belgie 20070101
Title: Additive risk survival model with microarray data.
Journal: BMC bioinformatics 20070101
Title: Synergistic activity of troxacitabine (Troxatyl) and gemcitabine in pancreatic cancer.
Journal: BMC cancer 20070101
Title: Protease inhibitor associated mutations compromise the efficacy of therapy in human immunodeficiency virus-1 (HIV-1) infected pediatric patients: a cross-sectional study.
Journal: AIDS research and therapy 20070101
Title: Electrospray tandem mass spectroscopic characterisation of 18 antiretroviral drugs and simultaneous quantification of 12 antiretrovirals in plasma.
Journal: Rapid communications in mass spectrometry : RCM 20070101
Title: The HIV RNA setpoint theory revisited.
Journal: Retrovirology 20070101
Title: Utilization and spending trends for antiretroviral medications in the U.S. Medicaid program from 1991 to 2005.
Journal: AIDS research and therapy 20070101
Title: Bcl11b mutations identified in murine lymphomas increase the proliferation rate of hematopoietic progenitor cells.
Journal: BMC cancer 20070101
Title: Biological activity of 3-formylchromones and related compounds.
Journal: In vivo (Athens, Greece) 20070101
Title: Insights on resistance to reverse transcriptase: the different patterns of interaction of the nucleoside reverse transcriptase inhibitors in the deoxyribonucleotide triphosphate binding site relative to the normal substrate.
Journal: Journal of medicinal chemistry 20061228
Title: Induction of thymidine phosphorylase expression by AZT contributes to enhancement of 5'-DFUR cytotoxicity.
Journal: Cancer letters 20061208
Title: Rapid and random turnover of mitochondrial DNA in rat hepatocytes of primary culture.
Journal: Mitochondrion 20061201
Title: Alterations to the expression level of mitochondrial transcription factor A, TFAM, modify the mode of mitochondrial DNA replication in cultured human cells.
Journal: Nucleic acids research 20061101
Title: Paclitaxel- and vincristine-evoked painful peripheral neuropathies: loss of epidermal innervation and activation of Langerhans cells.
Journal: Experimental neurology 20061001
Title: In vitro antiviral activities of Chinese medicinal herbs against duck hepatitis B virus.
Journal: Phytotherapy research : PTR 20061001
Title: Monitoring the toxicity of antiretroviral therapy in resource limited settings: a prospective clinical trial cohort in Thailand.
Journal: The Journal of antimicrobial chemotherapy 20060901
Title: Microarray analysis during adipogenesis identifies new genes altered by antiretroviral drugs.
Journal: AIDS (London, England) 20060822
Title: [Central nervous system HIV-associated polyarteritis nodosa: long-term outcome].
Journal: La Revue de medecine interne 20060801
Title: Flow-injection spectrophotometric determination of reverse transcriptase inhibitors used for acquired immuno deficiency syndrome (AIDS) treatment: focus on strategies for dealing with the background components.
Journal: Analytica chimica acta 20060714
Title: Distal sensory polyneuropathy in HIV-positive patients in the HAART era: an entity underestimated by clinical examination.
Journal: International journal of STD & AIDS 20060701
Title: A randomised trial comparing genotypic and virtual phenotypic interpretation of HIV drug resistance: the CREST study.
Journal: PLoS clinical trials 20060701
Title: Real-time nucleic acid sequence-based amplification assay to quantify changes in mitochondrial DNA concentrations in cell cultures and blood cells from HIV-infected patients receiving antiviral therapy.
Journal: Clinical chemistry 20060601
Title: Antiretroviral drug resistance and routine therapy, Cameroon.
Journal: Emerging infectious diseases 20060601
Title: A prospective study of Kaposi's sarcoma-associated herpesvirus and Epstein-Barr virus in adults with human immunodeficiency virus-1.
Journal: British journal of cancer 20060522
Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.
Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
Title: Dysregulation of cellular calcium homeostasis in chemotherapy-evoked painful peripheral neuropathy.
Journal: Anesthesia and analgesia 20060501
Title: dD4FC development discontinued.
Journal: AIDS clinical care 20060501
Title: Interaction of zalcitabine with human organic anion transporter 1.
Journal: Die Pharmazie 20060501
Title: mtDNA controls expression of the Death Associated Protein 3.
Journal: Experimental cell research 20060401
Title: Influence of HCV or HBV coinfection on adverse drug reactions to antiretroviral drugs in HIV patients.
Journal: European journal of clinical pharmacology 20060301
Title: Mitochondrial electron transport in models of neuropathic and inflammatory pain.
Journal: Pain 20060301
Title: Simultaneous determination of 16 anti-HIV drugs in human plasma by high-performance liquid chromatography.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20060202
Title: In vitro antiretroviral activity and in vitro toxicity profile of SPD754, a new deoxycytidine nucleoside reverse transcriptase inhibitor for treatment of human immunodeficiency virus infection.
Journal: Antimicrobial agents and chemotherapy 20060201
Title: Simple adjustments for randomized trials with nonrandomly missing or censored outcomes arising from informative covariates.
Journal: Biostatistics (Oxford, England) 20060101
Title: Altered pharmacokinetics of zalcitabine by concurrent use of NSAIDs in rats.
Journal: Acta pharmacologica Sinica 20060101
Title: The distribution of the anti-HIV drug, tenofovir (PMPA), into the brain, CSF and choroid plexuses.
Journal: Cerebrospinal fluid research 20060101
Title: [Mitochondrial cytopathies associated with HIV infection].
Journal: Revue neurologique 20060101
Title: Uridine abrogates the adverse effects of antiretroviral pyrimidine analogues on adipose cell functions.
Journal: Antiviral therapy 20060101
Title: DR_SEQAN: a PC/Windows-based software to evaluate drug resistance using human immunodeficiency virus type 1 genotypes.
Journal: BMC infectious diseases 20060101
Title: Inhibition of highly productive HIV-1 infection in T cells, primary human macrophages, microglia, and astrocytes by Sargassum fusiforme.
Journal: AIDS research and therapy 20060101
Title: 2'-deoxy-4'-C-ethynyl-2-fluoroadenosine, a nucleoside reverse transcriptase inhibitor, is highly potent against all human immunodeficiency viruses type 1 and has low toxicity.
Journal: Chemical record (New York, N.Y.) 20060101
Title: Nuclear and mitochondrial genome responses in HeLa cells treated with inhibitors of mitochondrial DNA expression.
Journal: Acta biochimica Polonica 20060101
Title: Alterations of mitochondrial DNA in CEM cells selected for resistance toward ddC toxicity.
Journal: Nucleosides, nucleotides & nucleic acids 20060101
Title: 3'-Carbon-substituted pyrimidine nucleosides having a 2',3'-dideoxy and 2',3'-didehydro-2',3'-dideoxy structure: synthesis and antiviral evaluation.
Journal: Antiviral chemistry & chemotherapy 20060101
Title: Using cost-effectiveness analyses to inform policy: the case of antiretroviral therapy in Thailand.
Journal: Cost effectiveness and resource allocation : C/E 20060101
Title: Disease Management - Constructing Optimal NRTI-Based Combinations: Past, Present, and Future.
Journal: Journal of the International AIDS Society 20060101
Title: A combination of decreased NRTI incorporation and decreased excision determines the resistance profile of HIV-1 K65R RT.
Journal: AIDS (London, England) 20051104
Title: A direct comparison of drug susceptibility to HIV type 1 from antiretroviral experienced subjects as assessed by the antivirogram and PhenoSense assays and by seven resistance algorithms.
Journal: AIDS research and human retroviruses 20051101
Title: Newly designed six-membered azasugar nucleotide-containing phosphorothioate oligonucleotides as potent human immunodeficiency virus type 1 inhibitors.
Journal: Antimicrobial agents and chemotherapy 20051001
Title: HIV Pathogenesis and Treatment - Third International AIDS Society Conference.
Journal: IDrugs : the investigational drugs journal 20051001
Title: Meeting notes from the 3rd IAS Conference. New drugs.
Journal: AIDS clinical care 20051001
Title: Cytosine arabinoside affects multiple cellular factors and induces drug resistance in human lymphoid cells.
Journal: Biochemical pharmacology 20050801
Title: The broadly selective human Na+/nucleoside cotransporter (hCNT3) exhibits novel cation-coupled nucleoside transport characteristics.
Journal: The Journal of biological chemistry 20050708
Title: New drugs.
Journal: HIV medicine 20050701
Title: SIV-specific T lymphocyte responses in PBMC and lymphoid tissues of SIV-infected pigtailed macaques during suppressive combination antiretroviral therapy.
Journal: Journal of medical primatology 20050601
Title: Genotypic resistance analyses in nucleoside-pretreated patients failing an indinavir containing regimen: results from a randomized comparative trial: (Novavir ANRS 073).
Journal: Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 20050601
Title: Oxygen consumption by cultured human cells is impaired by a nucleoside analogue cocktail that inhibits mitochondrial DNA synthesis.
Journal: Mitochondrion 20050601
Title: Emerging anti-HIV drugs.
Journal: Expert opinion on emerging drugs 20050501
Title: Efficacy and safety of zidovudine and zalcitabine combined with a combination of herbs in the treatment of HIV-infected Thai patients.
Journal: The Southeast Asian journal of tropical medicine and public health 20050501
Title: Functional characterization of novel human and mouse equilibrative nucleoside transporters (hENT3 and mENT3) located in intracellular membranes.
Journal: The Journal of biological chemistry 20050422
Title: Synthesis of 2',3'-dideoxynucleoside 5'-alpha-P-borano-beta,gamma-(difluoromethylene)triphosphates and their inhibition of HIV-1 reverse transcriptase.
Journal: Journal of medicinal chemistry 20050407
Title: Gene repair in mammalian cells is stimulated by the elongation of S phase and transient stalling of replication forks.
Journal: DNA repair 20050404
Title: Nucleotide specificity of HIV-1 reverse transcriptases with amino acid substitutions affecting Ala-114.
Journal: The Biochemical journal 20050401
Title: Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: results of a global collaboration.
Journal: PLoS medicine 20050401
Title: The central nervous system is a viral reservoir in simian immunodeficiency virus--infected macaques on combined antiretroviral therapy: a model for human immunodeficiency virus patients on highly active antiretroviral therapy.
Journal: Journal of neurovirology 20050401
Title: Antiadenovirus activities of several classes of nucleoside and nucleotide analogues.
Journal: Antimicrobial agents and chemotherapy 20050301
Title: In vitro activity of structurally diverse nucleoside analogs against human immunodeficiency virus type 1 with the K65R mutation in reverse transcriptase.
Journal: Antimicrobial agents and chemotherapy 20050301
Title: Synthesis and evaluation of S-acyl-2-thioethyl esters of modified nucleoside 5'-monophosphates as inhibitors of hepatitis C virus RNA replication.
Journal: Journal of medicinal chemistry 20050224
Title: Detection of mitochondrial DNA depletion in living human cells using PicoGreen staining.
Journal: Experimental cell research 20050215
Title: Synthesis and antiviral activity of helioxanthin analogues.
Journal: Journal of medicinal chemistry 20050127
Title: Anti-HIV benzylisoquinoline alkaloids and flavonoids from the leaves of Nelumbo nucifera, and structure-activity correlations with related alkaloids.
Journal: Bioorganic & medicinal chemistry 20050117
Title: Development and validation of a liquid chromatographic/tandem mass spectrometric assay for the quantitation of nucleoside HIV reverse transcriptase inhibitors in biological matrices.
Journal: Journal of mass spectrometry : JMS 20050101
Title: Pancreatic exocrine insufficiency in HIV-positive patients.
Journal: HIV medicine 20050101
Title: Molecular strategies to inhibit HIV-1 replication.
Journal: Retrovirology 20050101
Title: Meeting notes from ICAAC. D-D4FC (Reverset): further data on treatment-experienced patients.
Journal: AIDS clinical care 20050101
Title: Mitochondrial toxicity of nucleoside analogues in primary human lymphocytes.
Journal: Antiviral therapy 20050101
Title: Comparative pharmacokinetics of Racivir, (+/-)-beta-2',3'-dideoxy-5-fluoro-3'-thiacytidine in rats, rabbits, dogs, monkeys and HIV-infected humans.
Journal: Antiviral chemistry & chemotherapy 20050101
Title: Incidence and risk factors for liver enzyme elevation during highly active antiretroviral therapy in HIV-HCV co-infected patients: results from the Italian EPOKA-MASTER Cohort.
Journal: BMC infectious diseases 20050101
Title: Muscle and liver lactate metabolism in HAART-treated and naive HIV-infected patients: the MITOVIR study.
Journal: Antiviral therapy 20050101
Title: ABC transporters as multidrug resistance mechanisms and the development of chemosensitizers for their reversal.
Journal: Cancer cell international 20050101
Title: Genetic barriers to resistance and impact on clinical response.
Journal: Journal of the International AIDS Society 20050101
Title: Caspase signalling in neuropathic and inflammatory pain in the rat.
Journal: The European journal of neuroscience 20041201
Title: Interaction of nucleoside inhibitors of HIV-1 reverse transcriptase with the concentrative nucleoside transporter-1 (SLC28A1).
Journal: Antiviral therapy 20041201
Title: Prevalence of genotypic resistance to nucleoside analogues and protease inhibitors in antiretroviral-naive HIV patients in Campania, Italy.
Journal: Journal of chemotherapy (Florence, Italy) 20041201
Title: Determination of 2',3'-dideoxycytidine in maternal plasma, amniotic fluid, placental and fetal tissues by high-performance liquid chromatography.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20041125
Title: CADA, a novel CD4-targeted HIV inhibitor, is synergistic with various anti-HIV drugs in vitro.
Journal: AIDS (London, England) 20041105
Title: The HIV-1 nucleoside reverse transcriptase inhibitors stavudine and zidovudine alter adipocyte functions in vitro.
Journal: AIDS (London, England) 20041105
Title: A 4'-C-ethynyl-2',3'-dideoxynucleoside analogue highlights the role of the 3'-OH in anti-HIV active 4'-C-ethynyl-2'-deoxy nucleosides.
Journal: Journal of medicinal chemistry 20041007
Title: New nucleoside reverse transcriptase inhibitors for the treatment of HIV infections.
Journal: Current opinion in pharmacology 20041001
Title: Effects of zidovudine, stavudine and beta-aminoisobutyric acid on lipid homeostasis in mice: possible role in human fat wasting.
Journal: Antiviral therapy 20041001
Title: 5-Fluoro-2'-deoxyuridine has effects on mitochondria in CEM T-lymphoblast cells.
Journal: Nucleosides, nucleotides & nucleic acids 20041001
Title: Binding of anti-HIV drugs to human serum albumin.
Journal: IUBMB life 20041001
Title: Primer unblocking by HIV-1 reverse transcriptase and resistance to nucleoside RT inhibitors (NRTIs).
Journal: The international journal of biochemistry & cell biology 20040901
Title: Phenotypic impact of HIV reverse transcriptase M184I/V mutations in combination with single thymidine analog mutations on nucleoside reverse transcriptase inhibitor resistance.
Journal: AIDS (London, England) 20040820
Title: Electrophysiological characterization of a recombinant human Na+-coupled nucleoside transporter (hCNT1) produced in Xenopus oocytes.
Journal: The Journal of physiology 20040801
Title: Rapid analysis of mitochondrial DNA depletion by fluorescence in situ hybridization and immunocytochemistry: potential strategies for HIV therapeutic monitoring.
Journal: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 20040801
Title: Validated RP-hPLC method for the assay of zalcitabine in drug substance, formulated products and human serum.
Journal: Die Pharmazie 20040801
Title: Potent antiviral effect of reverset in HIV-1-infected adults following a single oral dose.
Journal: Antiviral therapy 20040801
Title: The use of GAP-43 mRNA quantification in high throughput screening of putative neuroprotective agents in dorsal root ganglion cultures.
Journal: Journal of neuroscience methods 20040730
Title: HIV hollow fiber SCID model for antiviral therapy comparison with SCID/hu model.
Journal: Antiviral research 20040701
Title: Antiviral drugs in current clinical use.
Journal: Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 20040601
Title: [New approaches in the treatment of hepatitis B].
Journal: Deutsche medizinische Wochenschrift (1946) 20040521
Title: Synthesis and evaluation of novel prodrugs of foscarnet and dideoxycytidine with a universal carrier compound comprising a chemiluminescent and a photochromic conjugate.
Journal: Journal of pharmaceutical sciences 20040501
Title: Novel 4'-substituted stavudine analog with improved anti-human immunodeficiency virus activity and decreased cytotoxicity.
Journal: Antimicrobial agents and chemotherapy 20040501
Title: [Lactic acidosis in HIV-patients--diagnosis and treatment].
Journal: MMW Fortschritte der Medizin 20040426
Title: Investigating the effects of stereochemistry on incorporation and removal of 5-fluorocytidine analogs by mitochondrial DNA polymerase gamma: comparison of D- and L-D4FC-TP.
Journal: Antiviral research 20040401
Title: [Neuromuscular diseases associated with HIV-1 infection].
Journal: No to shinkei = Brain and nerve 20040401
Title: Effect of indinavir used alone or in double or triple combination with AZT and ddC on human immune functions.
Journal: Life sciences 20040319
Title: A survival method to estimate the time to occurrence of mutations: an application to thymidine analogue mutations in HIV-1-infected patients.
Journal: The Journal of infectious diseases 20040301
Title: Antiretroviral pipeline: new-drug reports from retroviruses conference.
Journal: AIDS treatment news 20040227
Title: Potent nonclassical nucleoside antiviral drugs based on the N,N-diarylformamidine concept.
Journal: Journal of medicinal chemistry 20040226
Title: Comparative evaluation of three computerized algorithms for prediction of antiretroviral susceptibility from HIV type 1 genotype.
Journal: The Journal of antimicrobial chemotherapy 20040201
Title: Efficacy and tolerability of zalcitabine twice daily (HIVBID Study).
Journal: Journal of acquired immune deficiency syndromes (1999) 20040201
Title: Depletion of mitochondrial DNA in liver under antiretroviral therapy with didanosine, stavudine, or zalcitabine.
Journal: Hepatology (Baltimore, Md.) 20040201
Title: Susceptibility of HIV-2, SIV and SHIV to various anti-HIV-1 compounds: implications for treatment and postexposure prophylaxis.
Journal: Antiviral therapy 20040201
Title: 2', 3'-Dideoxycytidine represses thymidine kinases 1 and 2 expression in T-lymphoid cells.
Journal: Life sciences 20040102
Title: Transport of physiological nucleosides and anti-viral and anti-neoplastic nucleoside drugs by recombinant Escherichia coli nucleoside-H(+) cotransporter (NupC) produced in Xenopus laevis oocytes.
Journal: Molecular membrane biology 20040101
Title: Novel mechanism of enhanced nociception in a model of AIDS therapy-induced painful peripheral neuropathy in the rat.
Journal: Pain 20040101
Title: Risk factors and occurrence of rash in HIV-positive patients not receiving nonnucleoside reverse transcriptase inhibitor: data from a randomized study evaluating use of protease inhibitors in nucleoside-experienced patients with very low CD4 levels (<50 cells/microL).
Journal: HIV medicine 20040101
Title: Greater and more rapid depletion of mitochondrial DNA in blood of patients treated with dual (zidovudine+didanosine or zidovudine+zalcitabine) vs. single (zidovudine) nucleoside reverse transcriptase inhibitors.
Journal: HIV medicine 20040101
Title: Inhibition of severe acute respiratory syndrome-associated coronavirus (SARSCoV) by calpain inhibitors and beta-D-N4-hydroxycytidine.
Journal: Antiviral chemistry & chemotherapy 20040101
Title: K65R, TAMs and tenofovir.
Journal: AIDS reviews 20040101
Title: Biochemical and mechanistic basis for the activity of nucleoside analogue inhibitors of HIV reverse transcriptase.
Journal: Current topics in medicinal chemistry 20040101
Title: Antiretrovirals, Part II: focus on non-protease inhibitor antiretrovirals (NRTIs, NNRTIs, and fusion inhibitors).
Journal: Psychosomatics 20040101
Title: Assessment of FIV-C infection of cats as a function of treatment with the protease inhibitor, TL-3.
Journal: Retrovirology 20040101
Title: Pharmacokinetics of antiretrovirals in pregnant women.
Journal: Clinical pharmacokinetics 20040101
Title: Toxicity of nucleoside analogues used to treat AIDS and the selectivity of the mitochondrial DNA polymerase.
Journal: Biochemistry 20031223
Title: Synthesis of potent CXCR4 inhibitors possessing low cytotoxicity and improved biostability based on T140 derivatives.
Journal: Organic & biomolecular chemistry 20031107
Title: Enhancement of the T140-based pharmacophores leads to the development of more potent and bio-stable CXCR4 antagonists.
Journal: Organic & biomolecular chemistry 20031107
Title: Synthesis and biological evaluation of some 5-nitro- and 5-amino derivatives of 2'-deoxycytidine, 2',3'-dideoxyuridine, and 2',3'-dideoxycytidine.
Journal: Nucleosides, nucleotides & nucleic acids 20031101
Title: Broad nucleoside reverse-transcriptase inhibitor cross-resistance in human immunodeficiency virus type 1 clinical isolates.
Journal: The Journal of infectious diseases 20031001
Title: Uridine abrogates mitochondrial toxicity related to nucleoside analogue reverse transcriptase inhibitors in HepG2 cells.
Journal: Antiviral therapy 20031001
Title: [Antiretroviral-induced toxiderma in HIV-infected patients].
Journal: Presse medicale (Paris, France : 1983) 20030906
Title: Contraindicated antiretroviral drug combinations.
Journal: New Jersey medicine : the journal of the Medical Society of New Jersey 20030901
Title: Nucleoside reverse transcriptase inhibitor usage and the incidence of peripheral neuropathy in HIV/AIDS patients.
Journal: Antiviral chemistry & chemotherapy 20030901
Title: Translesion replication in cisplatin-treated xeroderma pigmentosum variant cells is also caffeine-sensitive: features of the error-prone DNA polymerase(s) involved in UV-mutagenesis.
Journal: DNA repair 20030812
Title: MRP8, ATP-binding cassette C11 (ABCC11), is a cyclic nucleotide efflux pump and a resistance factor for fluoropyrimidines 2',3'-dideoxycytidine and 9'-(2'-phosphonylmethoxyethyl)adenine.
Journal: The Journal of biological chemistry 20030808
Title: In vitro antiviral activities of Caesalpinia pulcherrima and its related flavonoids.
Journal: The Journal of antimicrobial chemotherapy 20030801
Title: Quantitation of blood lymphocyte mitochondrial DNA for the monitoring of antiretroviral drug-induced mitochondrial DNA depletion.
Journal: Journal of acquired immune deficiency syndromes (1999) 20030801
Title: Susceptibility of human T cell leukemia virus type I to nucleoside reverse transcriptase inhibitors.
Journal: The Journal of infectious diseases 20030801
Title: Granuloma annulare masquerading as molluscum contagiosum-like eruption in an HIV-positive African woman.
Journal: Journal of the American Academy of Dermatology 20030801
Title: Comparison between rules-based human immunodeficiency virus type 1 genotype interpretations and real or virtual phenotype: concordance analysis and correlation with clinical outcome in heavily treated patients.
Journal: The Journal of infectious diseases 20030715
Title: Simultaneous determination of six HIV nucleoside analogue reverse transcriptase inhibitors and nevirapine by liquid chromatography with ultraviolet absorbance detection.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20030705
Title: Comparison of nine resistance interpretation systems for HIV-1 genotyping.
Journal: Antiviral therapy 20030601
Title: Structural determinants in human DNA polymerase gamma account for mitochondrial toxicity from nucleoside analogs.
Journal: Journal of molecular biology 20030523
Title: APHS can act synergically with clinically available HIV-1 reverse transcriptase and protease inhibitors and is active against several drug-resistant HIV-1 strains in vitro.
Journal: The Journal of antimicrobial chemotherapy 20030501
Title: A novel genetic pathway of human immunodeficiency virus type 1 resistance to stavudine mediated by the K65R mutation.
Journal: Journal of virology 20030501
Title: Probing the mechanistic consequences of 5-fluorine substitution on cytidine nucleotide analogue incorporation by HIV-1 reverse transcriptase.
Journal: Antiviral chemistry & chemotherapy 20030501
Title: [Antiviral effect of sulfated sialyl lipid against a clinical strain of adenovirus].
Journal: Nippon Ganka Gakkai zasshi 20030401
Title: N4-acyl-modified D-2',3'-dideoxy-5-fluorocytidine nucleoside analogues with improved antiviral activity.
Journal: Antiviral chemistry & chemotherapy 20030301
Title: Human immunodeficiency virus type-1 integrase containing a glycine to serine mutation at position 140 is attenuated for catalysis and resistant to integrase inhibitors.
Journal: Virology 20030201
Title: Predictive factors and selection of thymidine analogue mutations by nucleoside reverse transcriptase inhibitors according to initial regimen received.
Journal: Antiviral therapy 20030201
Title: Prognostic value of baseline human immunodeficiency virus type 1 DNA measurement for disease progression in patients receiving nucleoside therapy.
Journal: The Journal of infectious diseases 20030101
Title: Discrepant results in the interpretation of HIV-1 drug-resistance genotypic data among widely used algorithms.
Journal: HIV medicine 20030101
Title: Comparative effects of adefovir and selected nucleoside inhibitors of hepatitis B virus DNA polymerase on mitochondrial DNA in liver and skeletal muscle cells.
Journal: Journal of viral hepatitis 20030101
Title: Development and validation of a T7 based linear amplification for genomic DNA.
Journal: BMC genomics 20030101
Title: Self-reported health-related quality of life in persons with HIV infection: results from a multi-site interview project.
Journal: Health and quality of life outcomes 20030101
Title: Cellular pharmacology of D-d4FC, a nucleoside analogue active against drug-resistant HIV.
Journal: Antiviral chemistry & chemotherapy 20030101
Title: HIV-1 resistance profile of the novel nucleoside reverse transcriptase inhibitor beta-D-2',3'-dideoxy-2',3'-didehydro-5-fluorocytidine (Reverset).
Journal: Antiviral chemistry & chemotherapy 20030101
Title: Commentary on using the SF-36 or MOS-HIV in studies of persons with HIV disease.
Journal: Health and quality of life outcomes 20030101
Title: Oligomerization aiming at phosphonate analogues of oligoadenylates.
Journal: Nucleosides, nucleotides & nucleic acids 20030101
Title: Incorporation of (alpha-P-borano)-2',3'-dideoxycytidine 5'-triphosphate into DNA by drug-resistant MMLV reverse transcriptase and Taq DNA polymerase.
Journal: Nucleosides, nucleotides & nucleic acids 20030101
Title: Three- or four- versus two-drug antiretroviral maintenance regimens for HIV infection.
Journal: The Cochrane database of systematic reviews 20030101
Title: Insulin-like growth factor-1 protects ischemic murine myocardium from ischemia/reperfusion associated injury.
Journal: Critical care (London, England) 20030101
Title: Effect of zidovudine resistance mutations on virologic response to treatment with zidovudine or stavudine, each in combination with lamivudine and indinavir.
Journal: Journal of acquired immune deficiency syndromes (1999) 20021215
Title: Increased risk of lipoatrophy under stavudine in HIV-1-infected patients: results of a substudy from a comparative trial.
Journal: AIDS (London, England) 20021206
Title: Erratic expression of DNA polymerases by beta-amyloid causes neuronal death.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20021201
Title: Interactions of enantiomers of 2',3'-didehydro-2',3'-dideoxy-fluorocytidine with wild type and M184V mutant HIV-1 reverse transcriptase.
Journal: Antiviral research 20021201
Title: Antiviral activities and cellular toxicities of modified 2',3'-dideoxy-2',3'-didehydrocytidine analogues.
Journal: Antimicrobial agents and chemotherapy 20021201
Title: Theoretical mechanistic basis of the toxic effects and efficacy of AZT in HIV: AIDS.
Journal: Medical hypotheses 20021201
Title: Animal models for the study of HBV infection and the evaluation of new anti-HBV strategies.
Journal: Journal of gastroenterology and hepatology 20021201
Title: Treatment of adult T-cell leukemia-lymphoma by CHOP followed by therapy with antinucleosides, alpha interferon and oral etoposide.
Journal: Leukemia & lymphoma 20021201
Title: Increased long-term mitochondrial toxicity in combinations of nucleoside analogue reverse-transcriptase inhibitors.
Journal: AIDS (London, England) 20021108
Title: New anti-HIV agents and targets.
Journal: Medicinal research reviews 20021101
Title: New saponins from the starfish Certonardoa semiregularis.
Journal: Journal of natural products 20021101
Title: ACH-126443 Achillion/Yale University.
Journal: Current opinion in investigational drugs (London, England : 2000) 20021101
Title: Stereoselective synthesis and antiviral activity of D-2',3'-didehydro-2',3'-dideoxy-2'-fluoro-4'-thionucleosides.
Journal: Journal of medicinal chemistry 20021024
Title: Multidrug-resistant HIV-1 reverse transcriptase: involvement of ribonucleotide-dependent phosphorolysis in cross-resistance to nucleoside analogue inhibitors.
Journal: Journal of molecular biology 20021018
Title: Phenotypic and genotypic HIV-1 drug resistance assays provide complementary information.
Journal: Journal of acquired immune deficiency syndromes (1999) 20021001
Title: Predictors of treatment failure during highly active antiretroviral therapy (racing trial).
Journal: European journal of medical research 20020830
Title: A conserved Tyr residue is required for sugar selectivity in a Pol alpha DNA polymerase.
Journal: Biochemistry 20020813
Title: New developments in anti-HIV chemotherapy.
Journal: Biochimica et biophysica acta 20020718
Title: Perspectives on the molecular mechanism of inhibition and toxicity of nucleoside analogs that target HIV-1 reverse transcriptase.
Journal: Biochimica et biophysica acta 20020718
Title: 3'-Azido-2',3'-dideoxythymidine induced deficiency of thymidine kinases 1, 2 and deoxycytidine kinase in H9 T-lymphoid cells.
Journal: Biochemical pharmacology 20020715
Title: An ancient prevertebrate Na+-nucleoside cotransporter (hfCNT) from the Pacific hagfish (Eptatretus stouti).
Journal: American journal of physiology. Cell physiology 20020701
Title: ATP-dependent removal of nucleoside reverse transcriptase inhibitors by human immunodeficiency virus type 1 reverse transcriptase.
Journal: Antimicrobial agents and chemotherapy 20020701
Title: Exposure to dideoxynucleosides is reflected in lowered mitochondrial DNA in subcutaneous fat.
Journal: Journal of acquired immune deficiency syndromes (1999) 20020701
Title: Comparison of virtual phenotype and HIV-SEQ program (Stanford) interpretation for predicting drug resistance of HIV strains.
Journal: HIV medicine 20020701
Title: Genotypic and phenotypic analysis of a novel 15-base insertion occurring between codons 69 and 70 of HIV type 1 reverse transcriptase.
Journal: AIDS research and human retroviruses 20020701
Title: [Mononucleosis syndrome with viro-immunologic parameters similar to those of a primary HIV-1 infection after interruption of highly effective anti-retroviral treatment].
Journal: Anales de medicina interna (Madrid, Spain : 1984) 20020601
Title: Selection of a T-cell line resistant to stavudine and zidovudine by prolonged treatment with stavudine.
Journal: Antiviral therapy 20020601
Title: A rapid phenotypic assay for detecting multiple nucleoside analogue reverse transcriptase inhibitor-resistant HIV-1 in plasma.
Journal: Antiviral therapy 20020601
Title: Certification of the critical importance of L-3-(2-naphthyl)alanine at position 3 of a specific CXCR4 inhibitor, T140, leads to an exploratory performance of its downsizing study.
Journal: Bioorganic & medicinal chemistry 20020501
Title: Point mutations and deletions in the znfn1a1/ikaros gene in chemically induced murine lymphomas.
Journal: Cancer research 20020501
Title: Concurrent analysis of nucleoside reverse transcriptase inhibitors in a pool of endogenous nucleosides by short-end injection-capillary electrochromatography on a beta-cyclodextrin-bonded stationary phase.
Journal: Electrophoresis 20020501
Title: Impact of highly active antiretroviral therapy on cognitive processing in HIV infection: cross-sectional and longitudinal studies of event-related potentials.
Journal: AIDS research and human retroviruses 20020501
Title: Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.
Journal: The Journal of biological chemistry 20020419
Title: Tenofovir exhibits low cytotoxicity in various human cell types: comparison with other nucleoside reverse transcriptase inhibitors.
Journal: Antiviral research 20020401
Title: Enhanced inhibition of orthopoxvirus replication in vitro by alkoxyalkyl esters of cidofovir and cyclic cidofovir.
Journal: Antimicrobial agents and chemotherapy 20020401
Title: Broad nucleoside-analogue resistance implications for human immunodeficiency virus type 1 reverse-transcriptase mutations at codons 44 and 118.
Journal: The Journal of infectious diseases 20020401
Title: The dangers of inferring treatment effects from observational data: a case study in HIV infection.
Journal: Controlled clinical trials 20020401
Title: Dietary supplements in the treatment of nucleoside reverse transcriptase inhibitor-related mitochondrial toxicity.
Journal: AIDS (London, England) 20020329
Title: Assessment of mitochondrial toxicity in human cells treated with tenofovir: comparison with other nucleoside reverse transcriptase inhibitors.
Journal: Antimicrobial agents and chemotherapy 20020301
Title: Novel use of a guanosine prodrug approach to convert 2',3'-didehydro-2',3'-dideoxyguanosine into a viable antiviral agent.
Journal: Antimicrobial agents and chemotherapy 20020301
Title: ViroLogic announces agreement with Achillion.
Journal: Pharmacogenomics 20020301
Title: Observations of HIV-1 genotypic drug resistance in a trial of four reverse transcriptase inhibitors (Quattro Trial).
Journal: Antiviral therapy 20020301
Title: Prevalence of HIV-1 polymerase gene mutations in pre-treated patients in Thailand.
Journal: The Southeast Asian journal of tropical medicine and public health 20020301
Title: S-acyl-2-thioethyl (SATE) pronucleotides are potent inhibitors of HIV-1 replication in T-lymphoid cells cross-resistant to deoxycytidine and thymidine analogs.
Journal: Antiviral research 20020201
Title: Involvement of DNA polymerase beta in DNA replication and mutagenic consequences.
Journal: Journal of molecular biology 20020201
Title: The distribution of the anti-HIV drug, 2'3'-dideoxycytidine (ddC), across the blood-brain and blood-cerebrospinal fluid barriers and the influence of organic anion transport inhibitors.
Journal: Journal of neurochemistry 20020201
Title: Molecular basis of 2',3'-dideoxycytidine-induced drug resistance in human cells.
Journal: Molecular and cellular biochemistry 20020201
Title: Transbuccal delivery of 2',3'-dideoxycytidine: in vitro permeation study and histological investigation.
Journal: International journal of pharmaceutics 20020101
Title: Uptake of lamivudine by rat renal brush border membrane vesicles.
Journal: The Journal of pharmacy and pharmacology 20020101
Title: Viral and immunologic follow up of 4 to 9 years of AIDS treatments by quadruple combinations of virostatics including integrase inhibitors applied in short sequences differing by drug rotation.
Journal: Acta pharmacologica Sinica 20020101
Title: Fomivirsen: clinical pharmacology and potential drug interactions.
Journal: Clinical pharmacokinetics 20020101
Title: Novel direct detection method for quantitative determination of intracellular nucleoside triphosphates using weak anion exchange liquid chromatography/tandem mass spectrometry.
Journal: Rapid communications in mass spectrometry : RCM 20020101
Title: 'Senseless' antiviral polyribonucleotides: poly (1-propargylinosinic acid).
Journal: Nucleosides, nucleotides & nucleic acids 20020101
Title: A preliminary benefit-risk assessment of lamivudine for the treatment of chronic hepatitis B virus infection.
Journal: Drug safety 20020101
Title: A multicentre study to determine the efficacy and tolerability of a combination of nelfinavir (VIRACEPT), zalcitabine (HIVID) and zidovudine in the treatment of HIV infected Nigerian patients.
Journal: West African journal of medicine 20020101
Title: Antiviral activity of NMSO3 against adenovirus in vitro.
Journal: Antiviral research 20011201
Title: HIV-1 reverse transcriptase mutations found in a drug-experienced patient confer reduced susceptibility to multiple nucleoside reverse transcriptase inhibitors.
Journal: Antiviral therapy 20011201
Title: [Therapeutic aspects of HIV/AIDS infected patients and evaluation of therapeutic protocols].
Journal: Acta pharmaceutica Hungarica 20011201
Title: Increased ability for selection of zidovudine resistance in a distinct class of wild-type HIV-1 from drug-naive persons.
Journal: Proceedings of the National Academy of Sciences of the United States of America 20011120
Title: Anti-human immunodeficiency virus drugs are ineffective against Pneumocystis carinii in vitro and in vivo.
Journal: The Journal of infectious diseases 20011115
Title: New developments in anti-HIV chemotherapy.
Journal: Current medicinal chemistry 20011101
Title: Mitochondrial alterations with mitochondrial DNA depletion in the nerves of AIDS patients with peripheral neuropathy induced by 2'3'-dideoxycytidine (ddC).
Journal: Laboratory investigation; a journal of technical methods and pathology 20011101
Title: HIV-protease inhibitors alter retinoic acid synthesis.
Journal: AIDS (London, England) 20011019
Title: Mismatched double-stranded RNA (polyI-polyC(12)U) is synergistic with multiple anti-HIV drugs and is active against drug-sensitive and drug-resistant HIV-1 in vitro.
Journal: Antiviral research 20010901
Title: Antitumor activity of 2',3'-dideoxycytidine nucleotide analog against tumors up-regulating DNA polymerase beta.
Journal: Molecular pharmacology 20010901
Title: Functional characterization of rat organic anion transporter 2 in LLC-PK1 cells.
Journal: The Journal of pharmacology and experimental therapeutics 20010901
Title: Differential effects of nucleoside analogs on oxidative phosphorylation in human pancreatic cells.
Journal: Digestive diseases and sciences 20010901
Title: Simultaneous quantitation of nucleoside HIV-1 reverse transcriptase inhibitors by short-end injection capillary electrochromatography on a beta-cyclodextrin-bonded silica stationary phase.
Journal: Journal of chromatography. A 20010824
Title: Susceptibility of human T cell leukemia virus type 1 to reverse-transcriptase inhibitors: evidence for resistance to lamivudine.
Journal: The Journal of infectious diseases 20010815
Title: Do HIV type 1 RNA levels provide additional prognostic value to CD4(+) T lymphocyte counts in patients with advanced HIV type 1 infection?
Journal: AIDS research and human retroviruses 20010810
Title: Antiviral drugs: current state of the art.
Journal: Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 20010801
Title: Theoretical mechanistic basis of the toxic effects and efficacy of dideoxycytidine in HIV:AIDS.
Journal: Medical hypotheses 20010801
Title: Testing the reverse transcriptase model of somatic mutation.
Journal: Molecular immunology 20010801
Title: Development of specific CXCR4 inhibitors possessing high selectivity indexes as well as complete stability in serum based on an anti-HIV peptide T140.
Journal: Bioorganic & medicinal chemistry letters 20010723
Title: Association between zalcitabine therapy for human immunodeficiency virus and granuloma annulare?
Journal: Archives of dermatology 20010701
Title: Evidence for prolonged clinical benefit from initial combination antiretroviral therapy: Delta extended follow-up.
Journal: HIV medicine 20010701
Title: Differential incorporation and removal of antiviral deoxynucleotides by human DNA polymerase gamma.
Journal: The Journal of biological chemistry 20010629
Title: Insights into the molecular mechanism of mitochondrial toxicity by AIDS drugs.
Journal: The Journal of biological chemistry 20010629
Title: Analysis of human immunodeficiency virus type 1 drug resistance in children receiving nucleoside analogue reverse-transcriptase inhibitors plus nevirapine, nelfinavir, or ritonavir (Pediatric AIDS Clinical Trials Group 377).
Journal: The Journal of infectious diseases 20010615
Title: Crystal structures of a ddATP-, ddTTP-, ddCTP, and ddGTP- trapped ternary complex of Klentaq1: insights into nucleotide incorporation and selectivity.
Journal: Protein science : a publication of the Protein Society 20010601
Title: Biological activity of kiwifruit peel extracts.
Journal: Phytotherapy research : PTR 20010601
Title: 4'-Ethynyl nucleoside analogs: potent inhibitors of multidrug-resistant human immunodeficiency virus variants in vitro.
Journal: Antimicrobial agents and chemotherapy 20010501
Title: Synthesis and purification of oligonucleotide N3'-->P5' phosphoramidates and their phosphodiester and phosphorothioate chimeras.
Journal: Current protocols in nucleic acid chemistry 20010501
Title: Determination of serum levels of thirteen human immunodeficiency virus-suppressing drugs by high-performance liquid chromatography.
Journal: Journal of chromatography. A 20010413
Title: Maedi-visna virus, a model for in vitro testing of potential anti-HIV drugs.
Journal: Comparative immunology, microbiology and infectious diseases 20010401
Title: Antiviral activity of beta-L-2',3'-dideoxy-2',3'-didehydro-5-fluorocytidine in woodchucks chronically infected with woodchuck hepatitis virus.
Journal: Antimicrobial agents and chemotherapy 20010401
Title: Amino acid deletion at codon 67 and Thr-to-Gly change at codon 69 of human immunodeficiency virus type 1 reverse transcriptase confer novel drug resistance profiles.
Journal: Journal of virology 20010401
Title: Peripheral neuropathy during stavudine-didanosine antiretroviral therapy.
Journal: HIV medicine 20010401
Title: Human cytosolic 5'-nucleotidase I: characterization and role in nucleoside analog resistance.
Journal: The Journal of biological chemistry 20010330
Title: Mutations in the non-nucleoside binding-pocket interfere with the multi-nucleoside resistance phenotype.
Journal: AIDS (London, England) 20010330
Title: Therapeutic effects of nucleoside analogues on psychomotor slowing in HIV infection.
Journal: AIDS (London, England) 20010309
Title: Peripheral neuropathy and antiretroviral drugs.
Journal: Journal of the peripheral nervous system : JPNS 20010301
Title: Differential susceptibility of retroviruses to nucleoside analogues.
Journal: Antiviral chemistry & chemotherapy 20010301
Title: Antiretroviral treatments used among adults with HIV infection in Europe.
Journal: AIDS care 20010201
Title: Genetic risks of antiviral nucleoside analogues--a survey.
Journal: Antiviral research 20010201
Title: Synthesis and anti-HIV activity of nonatyrosine N- and O1-9-decasulfate.
Journal: Bioorganic & medicinal chemistry 20010201
Title: Synthesis and chain length-anti-HIV activity relationship of fully N- and O-sulfated homooligomers of tyrosine.
Journal: Bioorganic & medicinal chemistry 20010201
Title: [Determination of HIV RNA concentration for evaluation of the efficacy of combined therapy of HIV infection].
Journal: Klinicheskaia laboratornaia diagnostika 20010201
Title: Potential use of antiviral L(-)nucleoside analogues for the prevention or treatment of viral associated cancers.
Journal: Cancer letters 20010101
Title: Phosphorylation of nucleoside analog antiretrovirals: a review for clinicians.
Journal: Pharmacotherapy 20010101
Title: In vitro biological activity of prenylflavanones.
Journal: Anticancer research 20010101
Title: New developments in anti-HIV chemotherapy.
Journal: Farmaco (Societa chimica italiana : 1989) 20010101
Title: Clinical applications of a novel sustained-release injectable drug delivery system: DepoFoam technology.
Journal: Cancer journal (Sudbury, Mass.) 20010101
Title: Transport of antiviral 3'-deoxy-nucleoside drugs by recombinant human and rat equilibrative, nitrobenzylthioinosine (NBMPR)-insensitive (ENT2) nucleoside transporter proteins produced in Xenopus oocytes.
Journal: Molecular membrane biology 20010101
Title: Eruptive cheilitis: a new adverse effect in reactive HIV-positive patients subjected to high activity antiretroviral therapy (HAART). Presentation of six clinical cases.
Journal: Medicina oral : organo oficial de la Sociedad Espanola de Medicina Oral y de la Academia Iberoamericana de Patologia y Medicina Bucal 20010101
Title: Synthesis and antiviral evaluation of C-4-hydrazide derivatives of 2',3'-dideoxycytidine.
Journal: Nucleosides, nucleotides & nucleic acids 20010101
Title: Differential human immunodeficiency virus-suppressive activity of reverse transcription inhibitors in resting and activated peripheral blood lymphocytes: implications for therapy.
Journal: Journal of human virology 20010101
Title: The molecular basis of inhibition and toxicity of modified cytosine analogues targetting HIV-1 reverse transcriptase.
Journal: Antiviral chemistry & chemotherapy 20010101
Title: DABOs as candidates to prevent mucosal HIV transmission.
Journal: Antiviral chemistry & chemotherapy 20010101
Title: Mutational patterns in the HIV genome and cross-resistance following nucleoside and nucleotide analogue drug exposure.
Journal: Antiviral therapy 20010101
Title: MIKADO: a multicentre, open-label pilot study to evaluate the antiretroviral activity and safety of saquinavir with stavudine and zalcitabine.
Journal: HIV medicine 20010101
Title: Human immunodeficiency virus 1 strains resistant to nucleoside inhibitors of reverse transcriptase in isolates from the Czech Republic as monitored by line probe assay and nucleotide sequencing.
Journal: Acta virologica 20010101
Title: Inhibitory effect of human immunodeficiency virus protease inhibitors on multidrug resistance transporter P-glycoproteins.
Journal: Biological & pharmaceutical bulletin 20001201
Title: Synergistic inhibition of HIV-1 in activated and resting peripheral blood mononuclear cells, monocyte-derived macrophages, and selected drug-resistant isolates with nucleoside analogues combined with a natural product, resveratrol.
Journal: Journal of acquired immune deficiency syndromes (1999) 20001101
Title: Correlation between intracellular pharmacological activation of nucleoside analogues and HIV suppression in vitro.
Journal: Antiviral chemistry & chemotherapy 20001101
Title: Synthesis and biological evaluation of L- and D-configuration 1,3-dioxolane 5-azacytosine and 6-azathymine nucleosides.
Journal: Bioorganic & medicinal chemistry letters 20000918
Title: Prevalence and characteristics of multinucleoside-resistant human immunodeficiency virus type 1 among European patients receiving combinations of nucleoside analogues.
Journal: Antimicrobial agents and chemotherapy 20000801
Title: In vitro selection of mutations in the human immunodeficiency virus type 1 reverse transcriptase that decrease susceptibility to (-)-beta-D-dioxolane-guanosine and suppress resistance to 3'-azido-3'-deoxythymidine.
Journal: Antimicrobial agents and chemotherapy 20000701
Title: Presence of 2',5'-Bis-O-(tert-butyldimethylsilyl)-3'-spiro-5'-(4'-amino-1',2'-oxath iole-2',2'-dioxide) (TSAO)-resistant virus strains in TSAO-inexperienced HIV patients.
Journal: AIDS research and human retroviruses 20000610
Title: Synthesis and evaluation of 'AZT-HEPT', 'AZT-pyridinone', and 'ddC-HEPT' conjugates as inhibitors of HIV reverse transcriptase.
Journal: Journal of medicinal chemistry 20000518
Title: Selection and characterization of human immunodeficiency virus type 1 variants resistant to the (+) and (-) enantiomers of 2'-deoxy-3'-oxa-4'-thio-5-fluorocytidine.
Journal: Antimicrobial agents and chemotherapy 20000501
Title: Antiviral properties of a series of 1,6-naphthyridine and 7, 8-dihydroisoquinoline derivatives exhibiting potent activity against human cytomegalovirus.
Journal: Antimicrobial agents and chemotherapy 20000401
Title: Synthesis and biological activity of N-acylphenothiazines.
Journal: International journal of antimicrobial agents 20000401
Title: Activities of masked 2',3'-dideoxynucleoside monophosphate derivatives against human immunodeficiency virus in resting macrophages.
Journal: Antimicrobial agents and chemotherapy 20000101
Title: Potentiation of the anti-HIV activity of zalcitabine and lamivudine by a CTP synthase inhibitor, 3-deazauridine.
Journal: Nucleosides, nucleotides & nucleic acids 20000101
Title: Molecular mechanism of the short-term cardiotoxicity caused by 2',3'-dideoxycytidine (ddC): modulation of reactive oxygen species levels and ADP-ribosylation reactions.
Journal: Biochemical pharmacology 19991215
Title: Mechanism of action and in vitro activity of 1',3'-dioxolanylpurine nucleoside analogues against sensitive and drug-resistant human immunodeficiency virus type 1 variants.
Journal: Antimicrobial agents and chemotherapy 19991001
Title: A novel genotype encoding a single amino acid insertion and five other substitutions between residues 64 and 74 of the HIV-1 reverse transcriptase confers high-level cross-resistance to nucleoside reverse transcriptase inhibitors. Abacavir CNA2007 International Study Group.
Journal: Journal of acquired immune deficiency syndromes (1999) 19991001
Title: Mechanistic studies show that (-)-FTC-TP is a better inhibitor of HIV-1 reverse transcriptase than 3TC-TP.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 19990901
Title: Relation of peripheral neuropathy to HIV treatment in four randomized clinical trials including didanosine.
Journal: Clinical therapeutics 19990701
Title: Sensitivity of L-(-)2,3-dideoxythiacytidine resistant hepatitis B virus to other antiviral nucleoside analogues.
Journal: Biochemical pharmacology 19990615
Title: Synthesis and antiviral activity of 1-[1,5-dialkyl-1H-1,2,4-triazol-3-yl)methyl]thymines.
Journal: Archiv der Pharmazie 19990401
Title: Synthesis and biological evaluation of 2',3'-didehydro-2',3'- dideoxy-5-fluorocytidine (D4FC) analogues: discovery of carbocyclic nucleoside triphosphates with potent inhibitory activity against HIV-1 reverse transcriptase.
Journal: Journal of medicinal chemistry 19990311
Title: Effect of nucleoside analogs and non-nucleoside inhibitors of HIV-1 reverse transcriptase on cell-free virions.
Journal: Archives of virology 19990101
Title: 'Mixed inhibitors' of HIV-reverse transcriptase: synthesis and antiviral activity.
Journal: Nucleosides & nucleotides 19990101
Title: ddC- and 3TC-bis(SATE) monophosphate prodrugs overcome cellular resistance mechanisms to HIV-1 associated with cytidine kinase deficiency.
Journal: Nucleosides & nucleotides 19990101
Title: A low-molecular-weight inhibitor against the chemokine receptor CXCR4: a strong anti-HIV peptide T140.
Journal: Biochemical and biophysical research communications 19981230
Title: Antiviral oligo- and polyribonucleotides containing selected triazolo[2,3-a]purines.
Journal: Journal of medicinal chemistry 19981203
Title: Azidothymidine resistance of H9 human T-cell lymphoma cells is associated with decreased sensitivity to antitumor agents and inhibition of apoptosis.
Journal: International journal of molecular medicine 19981201
Title: Synthesis and comparative evaluation of two antiviral agents: beta-L-Fd4C and beta-D-Fd4C.
Journal: Bioorganic & medicinal chemistry letters 19981117
Title: Anti-AIDS agents. 34. Synthesis and structure-activity relationships of betulin derivatives as anti-HIV agents.
Journal: Journal of medicinal chemistry 19981105
Title: Coresistance to zidovudine and foscarnet is associated with multiple mutations in the human immunodeficiency virus type 1 reverse transcriptase.
Journal: Antimicrobial agents and chemotherapy 19981101
Title: Multiple dideoxynucleoside analogue-resistant (MddNR) HIV-1 strains isolated from patients from different European countries.
Journal: AIDS (London, England) 19981022
Title: Synthesis, structure and in vitro anti-human immunodeficiency virus activity of novel 3-methyl-1H,3H-thiazolo[3,4-a]benzimidazoles.
Journal: Antiviral chemistry & chemotherapy 19980901
Title: In vitro anti-human immunodeficiency virus (HIV) activity of the chromanone derivative, 12-oxocalanolide A, a novel NNRTI.
Journal: Bioorganic & medicinal chemistry letters 19980818
Title: Robustaflavone, a potential non-nucleoside anti-hepatitis B agent.
Journal: Antiviral research 19980801
Title: Metabolism of 2',3'-dideoxy-2',3'-didehydro-beta-L(-)-5-fluorocytidine and its activity in combination with clinically approved anti-human immunodeficiency virus beta-D(+) nucleoside analogs in vitro.
Journal: Antimicrobial agents and chemotherapy 19980701
Title: Anti-hepatitis B virus activity and metabolism of 2',3'-dideoxy-2',3'-didehydro-beta-L(-)-5-fluorocytidine.
Journal: Antimicrobial agents and chemotherapy 19980701
Title: (Z)- and (E)-2-(hydroxymethylcyclopropylidene)-methylpurines and pyrimidines as antiviral agents.
Journal: Antiviral chemistry & chemotherapy 19980701
Title: 3'-Azido-3'-deoxythymidine (AZT) mediates cross-resistance to nucleoside analogs in the case of AZT-resistant human immunodeficiency virus type 1 variants.
Journal: Journal of virology 19980601
Title: S-1153 inhibits replication of known drug-resistant strains of human immunodeficiency virus type 1.
Journal: Antimicrobial agents and chemotherapy 19980601
Title: Interaction of beta-L-2',3'-dideoxy-2',3'-didehydro-5-fluoro-CTP with human immunodeficiency virus-1 reverse transcriptase and human DNA polymerases: implications for human immunodeficiency virus drug design.
Journal: Molecular pharmacology 19980501
Title: Altered drug sensitivity, fitness, and evolution of human immunodeficiency virus type 1 with pol gene mutations conferring multi-dideoxynucleoside resistance.
Journal: The Journal of infectious diseases 19980501
Title: Tri-N-Boc-tetraazamacrocycle-nucleoside conjugates: synthesis and anti-HIV activities.
Journal: Nucleosides & nucleotides 19980501
Title: Inhibitory effects of novel nucleoside and nucleotide analogues on Epstein-Barr virus replication.
Journal: Antiviral chemistry & chemotherapy 19980501
Title: Synthesis and antiviral activity of novel acyclic nucleosides: discovery of a cyclopropyl nucleoside with potent inhibitory activity against herpesviruses.
Journal: Journal of medicinal chemistry 19980409
Title: Synergistic inhibition of HIV-1 by an antisense oligonucleotide and nucleoside analog reverse transcriptase inhibitors.
Journal: Antiviral research 19980401
Title: Retention of marked sensitivity to (S)-4-isopropoxycarbonyl-6-methoxy-3-(methylthiomethyl)-3,4-di hydroquin oxaline-2(1H)-thione (HBY 097) by an azidothymidine (AZT)-resistant human immunodeficiency virus type 1 (HIV-1) strain subcultured in the combined presence of quinoxaline HBY 097 and 2',3'-dideoxy-3'-thiacytidine (lamivudine).
Journal: Biochemical pharmacology 19980301
Title: [Hepatic steatosis during treatment with zidovudine and lamivudine in an HIV-positive patient].
Journal: Nederlands tijdschrift voor geneeskunde 19980221
Title: Inactivations of p16INK4a-alpha, p16INK4a-beta and p15INK4b genes in 2',3'-dideoxycytidine- and 1,3-butadiene-induced murine lymphomas.
Journal: Oncogene 19980212
Title: Effective lowly cytotoxic analogs of an HIV-cell fusion inhibitor, T22 ([Tyr5,12, Lys7]-polyphemusin II).
Journal: Bioorganic & medicinal chemistry 19980201
Title: Bis-S-acyl-2-thioethyl (SATE)-bearing monophosphate prodrug of beta-L-FD4C as potent anti-HBV agent.
Journal: Bioorganic & medicinal chemistry letters 19980106
Title: (Z)- and (E)-2-((hydroxymethyl)cyclopropylidene)methyladenine and -guanine. New nucleoside analogues with a broad-spectrum antiviral activity.
Journal: Journal of medicinal chemistry 19980101
Title: Thiazolo[4,5-d]pyrimidines. Part II. Synthesis and anti-human cytomegalovirus activity in vitro of certain acyclonucleosides and acyclonucleotides derived from the guanine analogue 5-aminothiazolo[4,5-d]pyrimidine-2,7(3H,6H)-dione.
Journal: Antiviral chemistry & chemotherapy 19980101
Title: Molecular cloning, functional expression and chromosomal localization of a cDNA encoding a human Na+/nucleoside cotransporter (hCNT2) selective for purine nucleosides and uridine.
Journal: Molecular membrane biology 19980101
Title: Characteristics of the Pro225His mutation in human immunodeficiency virus type 1 (HIV-1) reverse transcriptase that appears under selective pressure of dose-escalating quinoxaline treatment of HIV-1.
Journal: Journal of virology 19971101
Title: Susceptibility of human immunodeficiency virus type 1 group O isolates to antiretroviral agents: in vitro phenotypic and genotypic analyses.
Journal: Journal of virology 19971101
Title: Zidovudine-resistant human immunodeficiency virus type 1 strains subcultured in the presence of both lamivudine and quinoxaline HBY 097 retain marked sensitivity to HBY 097 but not to lamivudine.
Journal: The Journal of infectious diseases 19971101
Title: Anti-HIV activity of adefovir (PMEA) and PMPA in combination with antiretroviral compounds: in vitro analyses.
Journal: Antiviral research 19971101
Title: Inhibition of replication of hepatitis B virus by cytallene in vitro.
Journal: Antimicrobial agents and chemotherapy 19970801
Title: Synthesis and anti-HIV-1 activity of a series of 1-alkoxy-5-alkyl-6-(arylthio)uracils.
Journal: Journal of medicinal chemistry 19970718
Title: Genetic alterations of p53 and ras genes in 1,3-butadiene- and 2',3'-dideoxycytidine-induced lymphomas.
Journal: Cancer research 19970701
Title: Identification of BMS-200475 as a potent and selective inhibitor of hepatitis B virus.
Journal: Antimicrobial agents and chemotherapy 19970701
Title: Inhibition of replication of HIV in primary monocyte/macrophages by different antiviral drugs and comparative efficacy in lymphocytes.
Journal: Journal of leukocyte biology 19970701
Title: In vitro induction of human immunodeficiency virus type 1 variants resistant to 2'-beta-Fluoro-2',3'-dideoxyadenosine.
Journal: Antimicrobial agents and chemotherapy 19970601
Title: 1592U89, a novel carbocyclic nucleoside analog with potent, selective anti-human immunodeficiency virus activity.
Journal: Antimicrobial agents and chemotherapy 19970501
Title: Combination of mutations in human immunodeficiency virus type 1 reverse transcriptase required for resistance to the carbocyclic nucleoside 1592U89.
Journal: Antimicrobial agents and chemotherapy 19970501
Title: Lecithinized superoxide dismutase: an inhibitor of human immunodeficiency virus replication.
Journal: AIDS research and human retroviruses 19970301
Title: Irreversible ototoxicity associated with zalcitabine.
Journal: International journal of STD & AIDS 19970301
Title: Acetyl-carnitine deficiency in AIDS patients with neurotoxicity on treatment with antiretroviral nucleoside analogues.
Journal: AIDS (London, England) 19970201
Title: Stavudine selectively induces apoptosis in HIV type 1-infected cells.
Journal: AIDS research and human retroviruses 19970120
Title: Inhibition of sandfly fever Sicilian virus (Phlebovirus) replication in vitro by antiviral compounds.
Journal: Research in virology 19970101
Title: Chiral influences of feedback inhibition with dCTP on murine deoxycytidine kinase.
Journal: Nucleic acids symposium series 19970101
Title: Carcinogenicity of 2',3'-dideoxycytidine in mice.
Journal: Cancer research 19961015
Title: In vitro selection and molecular characterization of human immunodeficiency virus type 1 with reduced sensitivity to 9-[2-(phosphonomethoxy)ethyl]adenine (PMEA).
Journal: Antiviral research 19961001
Title: Significance of amino acid variation at human immunodeficiency virus type 1 reverse transcriptase residue 210 for zidovudine susceptibility.
Journal: Journal of virology 19960901
Title: Novel mutation (K70E) in human immunodeficiency virus type 1 reverse transcriptase confers decreased susceptibility to 9-[2-(phosphonomethoxy)ethyl]adenine in vitro.
Journal: Antimicrobial agents and chemotherapy 19960901
Title: Anti-HIV and anti-HBV activity and resistance profile of 2',3'-dideoxy-3'-thiacytidine (3TC) and its arylphosphoramidate derivative CF 1109.
Journal: Biochemical and biophysical research communications 19960814
Title: Low dose methotrexate, bleomycin, doxorubicin, cyclophosphamide, vincristine, and dexamethasone with zalcitabine in patients with acquired immunodeficiency syndrome-related lymphoma. Effect on human immunodeficiency virus and serum interleukin-6 levels over time.
Journal: Cancer 19960801
Title: Transport of the antiviral nucleoside analogs 3'-azido-3'-deoxythymidine and 2',3'-dideoxycytidine by a recombinant nucleoside transporter (rCNT) expressed in Xenopus laevis oocytes.
Journal: Molecular pharmacology 19960801
Title: Functional characterization of a recombinant sodium-dependent nucleoside transporter with selectivity for pyrimidine nucleosides (cNT1rat) by transient expression in cultured mammalian cells.
Journal: The Biochemical journal 19960715
Title: Allelotype analysis of 2',3'-dideoxycytidine- and 1,3-butadiene-induced lymphomas in B6C3F1 mice.
Journal: Cancer research 19960715
Title: Evaluation of reverse transcriptase and protease inhibitors in two-drug combinations against human immunodeficiency virus replication.
Journal: Antimicrobial agents and chemotherapy 19960601
Title: Marked inhibitory activity of non-nucleoside reverse transcriptase inhibitors against human immunodeficiency virus type 1 when combined with (-)2',3'-dideoxy-3'-thiacytidine.
Journal: Molecular pharmacology 19960501
Title: Synergistic inhibition of human immunodeficiency virus isolates (including 3'-azido-3'-deoxythymidine-resistant isolates) by foscarnet in combination with 2',3'-dideoxyinosine or 2',3'-dideoxycytidine.
Journal: Antimicrobial agents and chemotherapy 19960501
Title: Design and synthesis of 2',3'-dideoxy-2',3'-didehydro-beta-L-cytidine (beta-L-d4C) and 2',3'-dideoxy 2',3'-didehydro-beta-L-5-fluorocytidine (beta-L-Fd4C), two exceptionally potent inhibitors of human hepatitis B virus (HBV) and potent inhibitors of human immunodeficiency virus (HIV) in vitro.
Journal: Journal of medicinal chemistry 19960426
Title: Assessment of a cytoprotection assay for the discovery and evaluation of anti-human immunodeficiency virus compounds utilizing a genetically-impaired virus.
Journal: Journal of virological methods 19960426
Title: Low-dose zalcitabine-related toxic neuropathy: frequency, natural history, and risk factors.
Journal: Neurology 19960401
Title: Favorable interaction of beta-L(-) nucleoside analogues with clinically approved anti-HIV nucleoside analogues for the treatment of human immunodeficiency virus.
Journal: Biochemical pharmacology 19960322
Title: Synthesis, chromatographic resolution, and anti-human immunodeficiency virus activity of (+/-)-calanolide A and its enantiomers.
Journal: Journal of medicinal chemistry 19960315
Title: Protease inhibitors shine in triple combinations.
Journal: AIDS alert 19960301
Title: Multidrug-resistant human immunodeficiency virus type 1 strains resulting from combination antiretroviral therapy.
Journal: Journal of virology 19960201
Title: (-)-cis-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine (524W91) inhibits hepatitis B virus replication in primary human hepatocytes.
Journal: Antimicrobial agents and chemotherapy 19960201
Title: 3'-Azido-3'-deoxythymidine inhibits erythroid-specific transcription factors in human erythroid K562 leukemia cells.
Journal: European journal of haematology 19960101
Title: In vitro evaluation of combination therapies against hepatitis B virus replication.
Journal: Antiviral research 19960101
Title: Comparative analysis of anti-human immunodeficiency virus type 1 activities of dideoxynucleoside analogs in resting and activated peripheral blood mononuclear cells.
Journal: Antimicrobial agents and chemotherapy 19951101
Title: Inhibition of episomal hepatitis B virus DNA in vitro by 2,4-diamino-7- (2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-pyrrolo[2,3-d]pyrimidine.
Journal: Antimicrobial agents and chemotherapy 19951101
Title: Hepatitis B reactivation after lamivudine.
Journal: Lancet (London, England) 19951028
Title: Risk factors for dideoxynucleoside-induced toxic neuropathy in patients with the human immunodeficiency virus infection.
Journal: Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association 19951001
Title: Antiviral activity of a phosphorothioate oligonucleotide complementary to human cytomegalovirus RNA when used in combination with antiviral nucleoside analogs.
Journal: Antiviral research 19951001
Title: Phosphatidyl-2',3'-dideoxy-3'-thiacytidine: synthesis and antiviral activity in hepatitis B-and HIV-1-infected cells.
Journal: Antiviral research 19951001
Title: Characterisation of foscarnet-resistant strains of human immunodeficiency virus type 1.
Journal: Virology 19950910
Title: Disparate actions of hydroxyurea in potentiation of purine and pyrimidine 2',3'-dideoxynucleoside activities against replication of human immunodeficiency virus.
Journal: Proceedings of the National Academy of Sciences of the United States of America 19950829
Title: Potential mechanism for sustained antiretroviral efficacy of AZT-3TC combination therapy.
Journal: Science (New York, N.Y.) 19950804
Title: K65R mutation of human immunodeficiency virus type 1 reverse transcriptase encodes cross-resistance to 9-(2-phosphonylmethoxyethyl)adenine.
Journal: Antimicrobial agents and chemotherapy 19950801
Title: Mechanism of inhibition of duck hepatitis B virus polymerase by (-)-beta-L-2',3'-dideoxy-3'-thiacytidine.
Journal: Antimicrobial agents and chemotherapy 19950701
Title: Down-regulation of interleukin-2 receptor gene activation and protein expression by dideoxynucleoside analogs.
Journal: Cellular immunology 19950701
Title: The PETT series, a new class of potent nonnucleoside inhibitors of human immunodeficiency virus type 1 reverse transcriptase.
Journal: Antimicrobial agents and chemotherapy 19950601
Title: A simple and rapid method for preliminary evaluation of in vivo efficacy of anti-HIV compounds in mice.
Journal: Antiviral research 19950501
Title: Novel mutations in reverse transcriptase of human immunodeficiency virus type 1 reduce susceptibility to foscarnet in laboratory and clinical isolates.
Journal: Antimicrobial agents and chemotherapy 19950501
Title: Zalcitabine. Clinical pharmacokinetics and efficacy.
Journal: Clinical pharmacokinetics 19950501
Title: Comparative anti-HIV evaluation of diverse HIV-1-specific reverse transcriptase inhibitor-resistant virus isolates demonstrates the existence of distinct phenotypic subgroups.
Journal: Antiviral research 19950301
Title: The inhibition of human immunodeficiency virus type 1 in vitro by a non-nucleoside reverse transcriptase inhibitor MKC-442, alone and in combination with other anti-HIV compounds.
Journal: Antiviral research 19950301
Title: Exacerbation of peripheral neuropathy by lamivudine.
Journal: Lancet (London, England) 19950218
Title: Immunomodulatory and antiviral activities of 2',3'-dideoxy-beta-L-cytidine and 2',3'-dideoxy-beta-L-5-fluorocytidine.
Journal: Immunopharmacology and immunotoxicology 19950201
Title: Anti-human immunodeficiency virus and anti-hepatitis-B virus activities and toxicities of the enantiomers of 2'-deoxy-3'-oxa-4'-thiocytidine and their 5-fluoro analogues in vitro.
Journal: Journal of medicinal chemistry 19950106
Title: Effect of antiviral treatments on the bone marrow in murine aids.
Journal: Blood cells, molecules & diseases 19950101
Title: Inhibition of human immunodeficiency virus type 1 replication in cytokine-stimulated monocytes/macrophages by combination therapy.
Journal: The Journal of infectious diseases 19941201
Title: Pharmacokinetics, oral bioavailability, and metabolism in mice and cynomolgus monkeys of (2'R,5'S-)-cis-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl] cytosine, an agent active against human immunodeficiency virus and human hepatitis B virus.
Journal: Antimicrobial agents and chemotherapy 19941201
Title: Phosphatidylazidothymidine and phosphatidyl-ddC: assessment of uptake in mouse lymphoid tissues and antiviral activities in human immunodeficiency virus-infected cells and in Rauscher leukemia virus-infected mice.
Journal: Antimicrobial agents and chemotherapy 19941201
Title: Evidence that hepatocyte turnover is required for rapid clearance of duck hepatitis B virus during antiviral therapy of chronically infected ducks.
Journal: Journal of virology 19941201
Title: The K65R mutant reverse transcriptase of HIV-1 cross-resistant to 2', 3'-dideoxycytidine, 2',3'-dideoxy-3'-thiacytidine, and 2',3'-dideoxyinosine shows reduced sensitivity to specific dideoxynucleoside triphosphate inhibitors in vitro.
Journal: The Journal of biological chemistry 19941111
Title: Synergistic anti-human immunodeficiency virus type 1 effect of hydroxamate compounds with 2',3'-dideoxyinosine in infected resting human lymphocytes.
Journal: Proceedings of the National Academy of Sciences of the United States of America 19941108
Title: Synthesis and antiviral (HIV-1, HBV) activities of 5-halo-6-methoxy(or azido)-5,6-dihydro-3'-fluoro-3'-deoxythymidine diastereomers. Potential prodrugs to 3'-fluoro-3'-deoxythymidine.
Journal: Journal of medicinal chemistry 19941014
Title: Inhibition of human immunodeficiency virus type 1 reverse transcriptase by the 5'-triphosphate beta enantiomers of cytidine analogs.
Journal: Antimicrobial agents and chemotherapy 19941001
Title: Resistance of human immunodeficiency virus type 1 to acyclic 6-phenylselenenyl- and 6-phenylthiopyrimidines.
Journal: Antimicrobial agents and chemotherapy 19941001
Title: Synthesis and antiviral activity of new carbonylphosphonate 2',3'-dideoxy-3'-thiacytidine conjugates.
Journal: Antiviral research 19941001
Title: Deficiency of the human mitochondrial transcription factor h-mtTFA in infantile mitochondrial myopathy is associated with mtDNA depletion.
Journal: Human molecular genetics 19941001
Title: Anti-human immunodeficiency virus type 1 activity of hydroxyurea in combination with 2',3'-dideoxynucleosides.
Journal: Molecular pharmacology 19941001
Title: Inhibition of human immunodeficiency virus type 1 (HIV-1) replication by daphnodorins.
Journal: Antiviral research 19940901
Title: Cloning and functional expression of a complementary DNA encoding a mammalian nucleoside transport protein.
Journal: The Journal of biological chemistry 19940708
Title: Inhibition of human immunodeficiency virus type 1 replication by phosphonoformate- and phosphonoacetate-2',3'-dideoxy-3'-thiacytidine conjugates.
Journal: Journal of medicinal chemistry 19940708
Title: 5-Chloro-2',3'-dideoxy-3'-fluorouridine (935U83), a selective anti-human immunodeficiency virus agent with an improved metabolic and toxicological profile.
Journal: Antimicrobial agents and chemotherapy 19940701
Title: Novel mutation (V75T) in human immunodeficiency virus type 1 reverse transcriptase confers resistance to 2',3'-didehydro-2',3'-dideoxythymidine in cell culture.
Journal: Antimicrobial agents and chemotherapy 19940601
Title: In vitro susceptibility of clinical isolates of HIV-1 to XM323, a non-peptidyl HIV protease inhibitor.
Journal: AIDS (London, England) 19940601
Title: Anti-human immunodeficiency virus activities of the beta-L enantiomer of 2',3'-dideoxycytidine and its 5-fluoro derivative in vitro.
Journal: Antimicrobial agents and chemotherapy 19940601
Title: Suppression of HIV production in resting lymphocytes by combining didanosine and hydroxamate compounds.
Journal: Lancet (London, England) 19940521
Title: Mutagenic study of codons 74 and 215 of the human immunodeficiency virus type 1 reverse transcriptase, which are significant in nucleoside analog resistance.
Journal: Journal of virology 19940501
Title: Mitochondrial schwannopathy and peripheral myelinopathy in a rabbit model of dideoxycytidine neurotoxicity.
Journal: Laboratory investigation; a journal of technical methods and pathology 19940501
Title: Identification of novel mutations that confer drug resistance in the human immunodeficiency virus polymerase gene.
Journal: Leukemia 19940401
Title: Influence of stereochemistry on antiviral activities and resistance profiles of dideoxycytidine nucleosides.
Journal: Antimicrobial agents and chemotherapy 19940401
Title: Synthesis and biological evaluation of 2',3'-dideoxy-L-pyrimidine nucleosides as potential antiviral agents against human immunodeficiency virus (HIV) and hepatitis B virus (HBV).
Journal: Journal of medicinal chemistry 19940318
Title: Identification of a mutation at codon 65 in the IKKK motif of reverse transcriptase that encodes human immunodeficiency virus resistance to 2',3'-dideoxycytidine and 2',3'-dideoxy-3'-thiacytidine.
Journal: Antimicrobial agents and chemotherapy 19940201
Title: Resistance to 2',3'-dideoxycytidine conferred by a mutation in codon 65 of the human immunodeficiency virus type 1 reverse transcriptase.
Journal: Antimicrobial agents and chemotherapy 19940201
Title: Bisheteroarylpiperazine reverse transcriptase inhibitor in combination with 3'-azido-3'-deoxythymidine or 2',3'-dideoxycytidine synergistically inhibits human immunodeficiency virus type 1 replication in vitro.
Journal: Antimicrobial agents and chemotherapy 19940201
Title: Combinative interactions of a human immunodeficiency virus (HIV) Tat antagonist with HIV reverse transcriptase inhibitors and an HIV protease inhibitor.
Journal: Antimicrobial agents and chemotherapy 19940201
Title: Antiviral activity of 2',3'-dideoxy-beta-L-5-fluorocytidine (beta-L-FddC) and 2',3'-dideoxy-beta-L-cytidine (beta-L-ddC) against hepatitis B virus and human immunodeficiency virus type 1 in vitro.
Journal: Biochemical pharmacology 19940120
Title: Anti-HIV activity of dideoxynucleosides, foscarnet and fusidic acid is potentiated by human leukocyte interferon in blood-derived macrophages.
Journal: Chemotherapy 19940101
Title: Anti-angiogenesis agent DS-4152 is a potent and selective inhibitor of HIV-1 replication in vitro.
Journal: AIDS (London, England) 19940101
Title: Inhibition of HIV in vitro by antiviral drug-targeting using nanoparticles.
Journal: Research in virology 19940101
Title: Enantiomeric 2',3'-dideoxycytidine derivatives are potent human immunodeficiency virus inhibitors in cell cultures.
Journal: Comptes rendus de l'Academie des sciences. Serie III, Sciences de la vie 19940101
Title: Human immunodeficiency virus type 1 pol gene mutations in an AIDS patient treated with multiple antiretroviral drugs.
Journal: Journal of virology 19931201
Title: The biochemical basis for the differential anti-human immunodeficiency virus activity of two cis enantiomers of 2',3'-dideoxy-3'-thiacytidine.
Journal: The Journal of biological chemistry 19931105
Title: High-level resistance to (-) enantiomeric 2'-deoxy-3'-thiacytidine in vitro is due to one amino acid substitution in the catalytic site of human immunodeficiency virus type 1 reverse transcriptase.
Journal: Antimicrobial agents and chemotherapy 19931001
Title: Knocking-out concentrations of HIV-1-specific inhibitors completely suppress HIV-1 infection and prevent the emergence of drug-resistant virus.
Journal: Virology 19931001
Title: Anti-human immunodeficiency virus type 1 therapy and peripheral neuropathy: prevention of 2',3'-dideoxycytidine toxicity in PC12 cells, a neuronal model, by uridine and pyruvate.
Journal: Molecular pharmacology 19931001
Title: In vitro isolation and identification of human immunodeficiency virus (HIV) variants with reduced sensitivity to C-2 symmetrical inhibitors of HIV type 1 protease.
Journal: Proceedings of the National Academy of Sciences of the United States of America 19930815
Title: Human immunodeficiency virus type 1 (HIV-1) strains selected for resistance against the HIV-1-specific [2',5'-bis-O-(tert-butyldimethylsilyl)-3'-spiro- 5''-(4''-amino-1'',2''-oxathiole-2'',2''-dioxide)]-beta-D-pentofurano syl (TSAO) nucleoside analogues retain sensitivity to HIV-1-specific nonnucleoside inhibitors.
Journal: Proceedings of the National Academy of Sciences of the United States of America 19930801
Title: The 5'-triphosphates of the (-) and (+) enantiomers of cis-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolane-5-yl]cytosine equally inhibit human immunodeficiency virus type 1 reverse transcriptase.
Journal: Antimicrobial agents and chemotherapy 19930801
Title: pol mutations conferring zidovudine and didanosine resistance with different effects in vitro yield multiply resistant human immunodeficiency virus type 1 isolates in vivo.
Journal: Antimicrobial agents and chemotherapy 19930701
Title: Rapid in vitro selection of human immunodeficiency virus type 1 resistant to 3'-thiacytidine inhibitors due to a mutation in the YMDD region of reverse transcriptase.
Journal: Proceedings of the National Academy of Sciences of the United States of America 19930615
Title: Inhibitory effect of 9-(2-phosphonylmethoxyethyl)-adenine (PMEA) on human and duck hepatitis B virus infection.
Journal: Antiviral research 19930601
Title: The same mutation that encodes low-level human immunodeficiency virus type 1 resistance to 2',3'-dideoxyinosine and 2',3'-dideoxycytidine confers high-level resistance to the (-) enantiomer of 2',3'-dideoxy-3'-thiacytidine.
Journal: Antimicrobial agents and chemotherapy 19930601
Title: U-90152, a potent inhibitor of human immunodeficiency virus type 1 replication.
Journal: Antimicrobial agents and chemotherapy 19930501
Title: In vitro anti-human immunodeficiency virus activity of 2',3'-dideoxynucleosides and their effect on clonal growth of hemopoietic cells from human bone marrow.
Journal: Arzneimittel-Forschung 19930501
Title: Characterization of human immunodeficiency viruses resistant to oxathiolane-cytosine nucleosides.
Journal: Antimicrobial agents and chemotherapy 19930401
Title: Zalcitabine.
Journal: The Annals of pharmacotherapy 19930401
Title: Alternating and intermittent regimens of zidovudine and dideoxycytidine in patients with AIDS or AIDS-related complex.
Journal: Annals of internal medicine 19930301
Title: 2',3'-dideoxycytidine (ddC) toxic neuropathy: a study of 52 patients.
Journal: Neurology 19930201
Title: Human immunodeficiency virus type 1-specific [2',5'-bis-O-(tert- butyldimethylsilyl)-beta-D-ribofuranosyl]-3'-spiro-5'-(4'-amino-1',2'- oxathiole-2',2'-dioxide)-purine analogues show a resistance spectrum that is different from that of the human immunodeficiency virus type 1-specific non-nucleoside analogues.
Journal: Molecular pharmacology 19930101
Title: A single conservative amino acid substitution in the reverse transcriptase of human immunodeficiency virus-1 confers resistance to (+)-(5S)-4,5,6,7-tetrahydro-5-methyl-6-(3-methyl-2-butenyl)imidazo[4,5, 1- jk][1,4]benzodiazepin-2(1H)-thione (TIBO R82150).
Journal: Molecular pharmacology 19930101
Title: HIV-1-specific reverse transcriptase inhibitors show differential activity against HIV-1 mutant strains containing different amino acid substitutions in the reverse transcriptase.
Journal: Virology 19930101
Title: Characterization of 2',3'-dideoxycytidine diphosphocholine and 2',3'-dideoxycytidine diphosphoethanolamine. Prominent phosphodiester metabolites of the anti-HIV nucleoside 2',3'-dideoxycytidine.
Journal: Drug metabolism and disposition: the biological fate of chemicals 19930101
Title: Generation of drug-resistant variants of human immunodeficiency virus type 1 by in vitro passage in increasing concentrations of 2',3'-dideoxycytidine and 2',3'-dideoxy-3'-thiacytidine.
Journal: Antimicrobial agents and chemotherapy 19930101
Title: Novel mutation in the human immunodeficiency virus type 1 reverse transcriptase gene that encodes cross-resistance to 2',3'-dideoxyinosine and 2',3'-dideoxycytidine.
Journal: Journal of virology 19921201
Title: The safety and pharmacokinetics of a reverse transcriptase inhibitor, 3TC, in patients with HIV infection: a phase I study.
Journal: AIDS (London, England) 19921201
Title: The anti-hepatitis B virus activities, cytotoxicities, and anabolic profiles of the (-) and (+) enantiomers of cis-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine.
Journal: Antimicrobial agents and chemotherapy 19921201
Title: Selective inhibition of human immunodeficiency viruses by racemates and enantiomers of cis-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine.
Journal: Antimicrobial agents and chemotherapy 19921101
Title: Effects of (-)-2'-deoxy-3'-thiacytidine (3TC) 5'-triphosphate on human immunodeficiency virus reverse transcriptase and mammalian DNA polymerases alpha, beta, and gamma.
Journal: Antimicrobial agents and chemotherapy 19920801
Title: Anti-HIV-I activity of linked lexitropsins.
Journal: Journal of medicinal chemistry 19920724
Title: Potential prodrug derivatives of 2',3'-didehydro-2',3'-dideoxynucleosides. Preparations and antiviral activities.
Journal: Journal of medicinal chemistry 19920724
Title: Synergistic inhibition of replication of human immunodeficiency virus type 1, including that of a zidovudine-resistant isolate, by zidovudine and 2',3'-dideoxycytidine in vitro.
Journal: Antimicrobial agents and chemotherapy 19920701
Title: Use of a standardized cell culture assay to assess activities of nucleoside analogs against hepatitis B virus replication.
Journal: Antiviral research 19920701
Title: Chemistry and anti-HIV properties of 2'-fluoro-2',3'-dideoxyarabinofuranosylpyrimidines.
Journal: Journal of medicinal chemistry 19920612
Title: Highly water-soluble lipophilic prodrugs of the anti-HIV nucleoside analogue 2',3'-dideoxycytidine and its 3'-fluoro derivative.
Journal: Journal of medicinal chemistry 19920529
Title: Synthesis and anti-HIV activity of 9-[c-4,t-5-bis(hydroxymethyl)cyclopent-2-en-r-1-yl]-9H-adenine.
Journal: Journal of medicinal chemistry 19920515
Title: Resolution of 9-(c-4,t-5-bishydroxymethylcyclopent-2-en-r-1-yl)-9H-adenine and selective inhibition of human immunodeficiency virus by the (-) enantiomer.
Journal: Biochemical and biophysical research communications 19920415
Title: (-)-2'-deoxy-3'-thiacytidine is a potent, highly selective inhibitor of human immunodeficiency virus type 1 and type 2 replication in vitro.
Journal: Antimicrobial agents and chemotherapy 19920401
Title: Aryl phosphate derivatives of AZT retain activity against HIV1 in cell lines which are resistant to the action of AZT.
Journal: Antiviral research 19920401
Title: Activities of the four optical isomers of 2',3'-dideoxy-3'-thiacytidine (BCH-189) against human immunodeficiency virus type 1 in human lymphocytes.
Journal: Antimicrobial agents and chemotherapy 19920301
Title: In vitro selection and molecular characterization of human immunodeficiency virus-1 resistant to non-nucleoside inhibitors of reverse transcriptase.
Journal: Molecular pharmacology 19920301
Title: Synthesis and anti-HIV activity of 4'-thio-2',3'-dideoxynucleosides.
Journal: Journal of medicinal chemistry 19920207
Title: Substrate specificity of human deoxycytidine kinase toward antiviral 2',3'-dideoxynucleoside analogs.
Journal: Biochemical pharmacology 19920122
Title: Peripheral neuropathy induced by 2',3'-dideoxycytidine. A rabbit model of 2',3'-dideoxycytidine neurotoxicity.
Journal: Laboratory investigation; a journal of technical methods and pathology 19920101
Title: Ultrastructure of peripheral neuropathy induced in rabbits by 2',3'-dideoxycytidine.
Journal: Laboratory investigation; a journal of technical methods and pathology 19920101
Title: Human immunodeficiency virus type 1 pol gene mutations which cause decreased susceptibility to 2',3'-dideoxycytidine.
Journal: Antimicrobial agents and chemotherapy 19920101
Title: The role of deoxycytidine-metabolizing enzymes in the cytotoxicity induced by 3'-amino-2',3'-dideoxycytidine and cytosine arabinoside.
Journal: Cancer chemotherapy and pharmacology 19920101
Title: In vitro selection of variants of human immunodeficiency virus type 1 resistant to 3'-azido-3'-deoxythymidine and 2',3'-dideoxyinosine.
Journal: Journal of virology 19920101
Title: Synthesis and anti-HIV-1 activity of 4,5,6,7-tetrahydro-5-methylimidazo[4,5,1-jk][1,4]benzodiazepin-2(1H)-on e (TIBO) derivatives. 2.
Journal: Journal of medicinal chemistry 19911101
Title: Inhibition of the replication of hepatitis B virus in vitro by 2',3'-dideoxy-3'-thiacytidine and related analogues.
Journal: Proceedings of the National Academy of Sciences of the United States of America 19911001
Title: Resistance to ddI and sensitivity to AZT induced by a mutation in HIV-1 reverse transcriptase.
Journal: Science (New York, N.Y.) 19910927
Title: 6-0-butanoylcastanospermine (MDL 28,574) inhibits glycoprotein processing and the growth of HIVs.
Journal: AIDS (London, England) 19910601
Title: Anti-HIV agents. I: Synthesis and in vitro anti-HIV evaluation of novel 1H,3H-thiazolo[3,4-a]benzimidazoles.
Journal: Farmaco (Societa chimica italiana : 1989) 19910601
Title: Biological comparison of wild-type and zidovudine-resistant isolates of human immunodeficiency virus type 1 from the same subjects: susceptibility and resistance to other drugs.
Journal: Antimicrobial agents and chemotherapy 19910501
Title: Effect of anti-human immunodeficiency virus nucleoside analogs on mitochondrial DNA and its implication for delayed toxicity.
Journal: Molecular pharmacology 19910501
Title: Potential anti-AIDS drugs. Lipophilic, adenosine deaminase-activated prodrugs.
Journal: Journal of medicinal chemistry 19910501
Title: The inhibitory activity of a peptide derivative against the growth of simian immunodeficiency virus in C8166 cells.
Journal: Biochemical and biophysical research communications 19910415
Title: Carbovir: the (-) enantiomer is a potent and selective antiviral agent against human immunodeficiency virus in vitro.
Journal: Antiviral research 19910201
Title: Inhibitory effects of selected antiviral compounds on human hepatitis B virus DNA synthesis.
Journal: Antimicrobial agents and chemotherapy 19910201
Title: Exacerbation of dideoxycytidine-induced neuropathy with dideoxyinosine.
Journal: Journal of acquired immune deficiency syndromes 19910101
Title: A new class of HIV-1-specific 6-substituted acyclouridine derivatives: synthesis and anti-HIV-1 activity of 5- or 6-substituted analogues of 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine (HEPT).
Journal: Journal of medicinal chemistry 19910101
Title: Synthesis of 2',3'-dideoxy-2',3'-alpha-methanocytidine.
Journal: Carbohydrate research 19900919
Title: Synthesis and anti-HIV-1 activity of 2'-'up'-fluoro analogues of active anti-AIDS nucleosides 3'-azido-3'-deoxythymidine (AZT) and 2',3'-dideoxycytidine (DDC).
Journal: Journal of medicinal chemistry 19900801
Title: Synthesis and antiviral activity of monofluoro and difluoro analogues of pyrimidine deoxyribonucleosides against human immunodeficiency virus (HIV-1).
Journal: Journal of medicinal chemistry 19900801
Title: Synthesis and anti-HIV activity of several 2'-fluoro-containing pyrimidine nucleosides.
Journal: Journal of medicinal chemistry 19900801
Title: 2',3'-Dideoxycytidine toxicity in cultured human CEM T lymphoblasts: effects of combination with 3'-azido-3'-deoxythymidine and thymidine.
Journal: Molecular pharmacology 19900801
Title: Ability of anti-HIV agents to inhibit HIV replication in monocyte/macrophages or U937 monocytoid cells under conditions of enhancement by GM-CSF or anti-HIV antibody.
Journal: AIDS research and human retroviruses 19900801
Title: Synthesis and biological evaluation of dinucleoside methylphosphonates of 3'-azido-3'-deoxythymidine and 2', 3'-dideoxycytidine.
Journal: Antiviral research 19900701
Title: Cross-resistance to anti-HIV nucleoside analogs in multidrug-resistant human cells.
Journal: Biochemical and biophysical research communications 19900629
Title: Synthesis and anti-HIV evaluation of 2',3'-dideoxyribo-5-chloropyrimidine analogues: reduced toxicity of 5-chlorinated 2',3'-dideoxynucleosides.
Journal: Journal of medicinal chemistry 19900601
Title: Susceptibility to nucleoside analogues of zidovudine-resistant isolates of human immunodeficiency virus.
Journal: The American journal of medicine 19900521
Title: Ototoxicity associated with dideoxycytidine.
Journal: Lancet (London, England) 19900505
Title: Inhibition of HIV-1 in monocyte/macrophage cultures by 2',3'-dideoxycytidine-5'-triphosphate, free and in liposomes.
Journal: AIDS research and human retroviruses 19900501
Title: American Society for Biochemistry and Molecular Biology, the American Association of Immunologists, joint meeting. New Orleans, Louisiana, June 4-7, 1990. Abstracts 1-3659, TU1-TU35, indexes.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 19900426
Title: Synthesis and antiretroviral activity of phospholipid analogs of azidothymidine and other antiviral nucleosides.
Journal: The Journal of biological chemistry 19900415
Title: Potent and selective inhibition of HIV-1 replication in vitro by a novel series of TIBO derivatives.
Journal: Nature 19900201
Title: Cyclobut-A and cyclobut-G, carbocyclic oxetanocin analogs that inhibit the replication of human immunodeficiency virus in T cells and monocytes and macrophages in vitro.
Journal: Antimicrobial agents and chemotherapy 19900201
Title: In vitro inhibition of the infectivity and replication of human immunodeficiency virus type 1 by combination of antiretroviral 2',3'-dideoxynucleosides and virus-binding inhibitors.
Journal: Antimicrobial agents and chemotherapy 19900101
Title: Antiretroviral activity, biochemistry, and pharmacokinetics of 3'-azido-2',3'-dideoxy-5-methylcytidine.
Journal: Annals of the New York Academy of Sciences 19900101
Title: Comparative studies of 2',3'-didehydro-2',3'-dideoxythymidine (D4T) with other pyrimidine nucleoside analogues.
Journal: Annals of the New York Academy of Sciences 19900101
Title: Inhibition of glycoprotein processing and HIV replication by castanospermine analogues.
Journal: Annals of the New York Academy of Sciences 19900101
Title: Synthesis and in vitro evaluation of some modified 4-thiopyrimidine nucleosides for prevention or reversal of AIDS-associated neurological disorders.
Journal: Journal of medicinal chemistry 19900101
Title: Synthesis and anti-HIV activity of carbocyclic 2',3'-didehydro-2',3'-dideoxy 2,6-disubstituted purine nucleosides.
Journal: Journal of medicinal chemistry 19900101
Title: Highly specific inhibition of human immunodeficiency virus type 1 by a novel 6-substituted acyclouridine derivative.
Journal: Biochemical and biophysical research communications 19891229
Title: A novel lead for specific anti-HIV-1 agents: 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine.
Journal: Journal of medicinal chemistry 19891201
Title: 2',3'-didehydro-2',3'-dideoxy-5-chlorocytidine is a selective anti-retrovirus agent.
Journal: Biochemical and biophysical research communications 19891115
Title: Reversible axonal neuropathy from the treatment of AIDS and related disorders with 2',3'-dideoxycytidine (ddC).
Journal: Muscle & nerve 19891001
Title: Human immunodeficiency virus inhibition is prolonged by 3'-azido-3'-deoxythymidine alternating with 2',3'-dideoxycytidine compared with 3'-azido-3'-deoxythymidine alone.
Journal: Antimicrobial agents and chemotherapy 19890601
Title: Dipyridamole potentiates the inhibition by 3'-azido-3'-deoxythymidine and other dideoxynucleosides of human immunodeficiency virus replication in monocyte-macrophages.
Journal: Proceedings of the National Academy of Sciences of the United States of America 19890501
Title: HIV with reduced sensitivity to zidovudine (AZT) isolated during prolonged therapy.
Journal: Science (New York, N.Y.) 19890331
Title: Replication of human immunodeficiency virus in monocytes. Granulocyte/macrophage colony-stimulating factor (GM-CSF) potentiates viral production yet enhances the antiviral effect mediated by 3'-azido-2'3'-dideoxythymidine (AZT) and other dideoxynucleoside congeners of thymidine.
Journal: The Journal of experimental medicine 19890301
Title: Susceptibility of human immunodeficiency virus to antiviral agents measured by infectious virus yield reduction.
Journal: Antiviral research 19890101
Title: Marked in vivo antiretrovirus activity of 9-(2-phosphonylmethoxyethyl)adenine, a selective anti-human immunodeficiency virus agent.
Journal: Proceedings of the National Academy of Sciences of the United States of America 19890101
Title: Enhanced in vitro inhibition of HIV-1 replication by 3'-fluoro-3'-deoxythymidine compared to several other nucleoside analogs.
Journal: AIDS research and human retroviruses 19881201
Title: Potent and selective activity of a new carbocyclic nucleoside analog (carbovir: NSC 614846) against human immunodeficiency virus in vitro.
Journal: Biochemical and biophysical research communications 19881031
Title: Comparative activity of 2',3'-saturated and unsaturated pyrimidine and purine nucleosides against human immunodeficiency virus type 1 in peripheral blood mononuclear cells.
Journal: Biochemical pharmacology 19881001
Title: Inhibition of human immunodeficiency virus (HIV-1/HTLV-IIIBa-L) replication in fresh and cultured human peripheral blood monocytes/macrophages by azidothymidine and related 2',3'-dideoxynucleosides.
Journal: The Journal of experimental medicine 19880901
Title: Rapid and automated tetrazolium-based colorimetric assay for the detection of anti-HIV compounds.
Journal: Journal of virological methods 19880801
Title: Synergistic interaction of 2',3'-dideoxycytidine and recombinant interferon-alpha-A on replication of human immunodeficiency virus type 1.
Journal: The Journal of infectious diseases 19880801
Title: Adenallene and cytallene: acyclic-nucleoside analogues that inhibit replication and cytopathic effect of human immunodeficiency virus in vitro.
Journal: Proceedings of the National Academy of Sciences of the United States of America 19880801
Title: Anti-retrovirus activity of 3'-fluoro- and 3'-azido-substituted pyrimidine 2',3'-dideoxynucleoside analogues.
Journal: Biochemical pharmacology 19880715
Title: The in vitro and in vivo anti-retrovirus activity, and intracellular metabolism of 3'-azido-2',3'-dideoxythymidine and 2',3'-dideoxycytidine are highly dependent on the cell species.
Journal: Biochemical pharmacology 19880301
Title: Potent and selective activity of 3'-azido-2,6-diaminopurine-2',3'-dideoxyriboside, 3'-fluoro-2,6-diaminopurine-2',3'-dideoxyriboside, and 3'-fluoro-2',3'-dideoxyguanosine against human immunodeficiency virus.
Journal: Molecular pharmacology 19880301
Title: 2',3'-Dideoxycytidine: regulation of its metabolism and anti-retroviral potency by natural pyrimidine nucleosides and by inhibitors of pyrimidine nucleotide synthesis.
Journal: Molecular pharmacology 19871201
Title: Dideoxynucleosides are less inhibitory in vitro against human immunodeficiency virus type 2 (HIV-2) than against HIV-1.
Journal: Antimicrobial agents and chemotherapy 19871201
Title: Ribavirin antagonizes inhibitory effects of pyrimidine 2',3'-dideoxynucleosides but enhances inhibitory effects of purine 2',3'-dideoxynucleosides on replication of human immunodeficiency virus in vitro.
Journal: Antimicrobial agents and chemotherapy 19871001
Title: Potent and selective in vitro activity of 3'-deoxythymidin-2'-ene (3'-deoxy-2',3'-didehydrothymidine) against human immunodeficiency virus.
Journal: Biochemical pharmacology 19870901
Title: 3'-substituted 2',3'-dideoxynucleoside analogues as potential anti-HIV (HTLV-III/LAV) agents.
Journal: Journal of medicinal chemistry 19870801
Title: The anti-HTLV-III (anti-HIV) and cytotoxic activity of 2',3'-didehydro-2',3'-dideoxyribonucleosides: a comparison with their parental 2',3'-dideoxyribonucleosides.
Journal: Molecular pharmacology 19870701
Title: Inhibitory effect of 2',3'-didehydro-2',3'-dideoxynucleosides on infectivity, cytopathic effects, and replication of human immunodeficiency virus.
Journal: Antimicrobial agents and chemotherapy 19870601
Title: Potential anti-AIDS drugs. 2',3'-Dideoxycytidine analogues.
Journal: Journal of medicinal chemistry 19870501
Title: Antiviral activity of 2',3'-dideoxycytidin-2'-ene (2',3'-dideoxy-2',3'-didehydrocytidine) against human immunodeficiency virus in vitro.
Journal: Biochemical pharmacology 19870201
Title: Synthesis and antiviral activity of various 3'-azido, 3'-amino, 2',3'-unsaturated, and 2',3'-dideoxy analogues of pyrimidine deoxyribonucleosides against retroviruses.
Journal: Journal of medicinal chemistry 19870201
Title: Both 2',3'-dideoxythymidine and its 2',3'-unsaturated derivative (2',3'-dideoxythymidinene) are potent and selective inhibitors of human immunodeficiency virus replication in vitro.
Journal: Biochemical and biophysical research communications 19870115
Title: Inhibition of the in vitro infectivity and cytopathic effect of human T-lymphotrophic virus type III/lymphadenopathy-associated virus (HTLV-III/LAV) by 2',3'-dideoxynucleosides.
Journal: Proceedings of the National Academy of Sciences of the United States of America 19860301
Title: Adkins JC, et al. Zalcitabine. An update of its pharmacodynamic and pharmacokinetic properties and clinical efficacy in the management of HIV infection.Drugs. 1997 Jun;53(6):1054-80
Title: Jin MJ, et al. Interaction of zalcitabine with human organic anion transporter 1. Pharmazie. 2006 May;61(5):491-2.
