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75187-63-2,MFCD00885567
Catalog No.:AA005DPO

75187-63-2 | 7,8-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-one

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250mg
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$16.00   $11.00
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5g
97%
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$57.00   $40.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA005DPO
Chemical Name:
7,8-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-one
CAS Number:
75187-63-2
Molecular Formula:
C15H10O5
Molecular Weight:
270.2369
MDL Number:
MFCD00885567
SMILES:
Oc1ccc(cc1)c1coc2c(c1=O)ccc(c2O)O
NSC Number:
678112
Properties
Properties
 
Form:
Solid  
MP:
>300°C  
Solubility:
DMSO: soluble10mg/mL, clear  
Storage:
Inert atmosphere;2-8℃;  

Computed Properties
 
Complexity:
411  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
20  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
1  
XLogP3:
2.1  

Downstream Synthesis Route

[1]Waehaelae,Kristiina;Hase,TapioA.[JournaloftheChemicalSociety.PerkintransactionsI,1991,#12,p.3005-3008]

75187-63-2    106-95-6   
8-allyloxy-4',7-dihydroxyisoflavone 
  229612-58-2   
7,8-diallyloxy-4'-hydroxyisoflavone 
 
4',7,8-triallyloxyisoflavone 

[1]Shiozaki,Masao[TetrahedronAsymmetry,1999,vol.10,#8,p.1477-1482]

[1]Li,Ming;Han,Xiuwen;Yu,Biao[JournalofOrganicChemistry,2003,vol.68,#17,p.6842-6845]

[1]Li,Ming;Han,Xiuwen;Yu,Biao[JournalofOrganicChemistry,2003,vol.68,#17,p.6842-6845]

Literature

Title: Synthesis and biological studies of 4', 7, 8-trihydroxy-isoflavone metal complexes.

Journal: Journal of inorganic biochemistry 20111201

Title: UHPLC method for the simultaneous determination of β-blockers, isoflavones and their metabolites in human urine.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20110315

Title: Evaluation of in vitro and in vivo depigmenting activity of raspberry ketone from Rheum officinale.

Journal: International journal of molecular sciences 20110101

Title: Study on the stability of deoxyArbutin in an anhydrous emulsion system.

Journal: International journal of molecular sciences 20110101

Title: Melanogenesis inhibitory activity of two generic drugs: cinnarizine and trazodone in mouse B16 melanoma cells.

Journal: International journal of molecular sciences 20110101

Title: Chemometric modeling of free radical scavenging activity of flavone derivatives.

Journal: European journal of medicinal chemistry 20101101

Title: Isoflavone derivatives inhibit NF-κB-dependent transcriptional activity.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: Natural ortho-dihydroxyisoflavone derivatives from aged Korean fermented soybean paste as potent tyrosinase and melanin formation inhibitors.

Journal: Bioorganic & medicinal chemistry letters 20100201

Title: Identifying 8-hydroxynaringenin as a suicide substrate of mushroom tyrosinase.

Journal: Journal of cosmetic science 20100101

Title: Determination of the thermodegradation of deoxyArbutin in aqueous solution by high performance liquid chromatography.

Journal: International journal of molecular sciences 20100101

Title: A-ring ortho-specific monohydroxylation of daidzein by cytochrome P450s of Nocardia farcinica IFM10152.

Journal: Biotechnology journal 20091101

Title: Evaluation of depigmenting activity by 8-hydroxydaidzein in mouse B16 melanoma cells and human volunteers.

Journal: International journal of molecular sciences 20091001

Title: Isolation of a new metabolite from biotransformation of daidzein by Aspergillus oryzae.

Journal: Bioscience, biotechnology, and biochemistry 20090801

Title: Antiplasmodial isoflavanones from the roots of Sophora mollis.

Journal: Journal of natural products 20090701

Title: An updated review of tyrosinase inhibitors.

Journal: International journal of molecular sciences 20090601

Title: 8-Hydroxydaidzein is unstable in alkaline solutions.

Journal: Journal of cosmetic science 20090101

Title: ortho-dihydroxyisoflavone derivatives from aged Doenjang (Korean fermented soypaste) and its radical scavenging activity.

Journal: Bioorganic & medicinal chemistry letters 20080915

Title: Polyphenols based on isoflavones as inhibitors of Helicobacter pylori urease.

Journal: Bioorganic & medicinal chemistry 20070601

Title: Metabolism of the soy isoflavones daidzein and genistein by fungi used in the preparation of various fermented soybean foods.

Journal: Bioscience, biotechnology, and biochemistry 20070501

Title: Two potent suicide substrates of mushroom tyrosinase: 7,8,4'-trihydroxyisoflavone and 5,7,8,4'-tetrahydroxyisoflavone.

Journal: Journal of agricultural and food chemistry 20070307

Title: Prostatic fluid concentrations of isoflavonoids in soy consumers are sufficient to inhibit growth of benign and malignant prostatic epithelial cells in vitro.

Journal: The Prostate 20060401

Title: Absorption and excretion of the 8-hydroxydaidzein in rats after oral administration and its antioxidant effect.

Journal: Journal of nutritional science and vitaminology 20050401

Title: Novel tempeh (fermented soyabean) isoflavones inhibit in vivo angiogenesis in the chicken chorioallantoic membrane assay.

Journal: The British journal of nutrition 20050301

Title: [Mechanism of mono-hydroxylation of daidzein in human liver microsomes].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20041101

Title: 8-Hydroxydaidzein, an aldose reductase inhibitor from okara fermented with Aspergillus sp. HK-388.

Journal: Bioscience, biotechnology, and biochemistry 20040701

Title: Isolation of 8-hydroxyglycitein and 6-hydroxydaidzein from soybean miso.

Journal: Bioscience, biotechnology, and biochemistry 20040601

Title: Effect of circulating forms of soy isoflavones on the oxidation of low density lipoprotein.

Journal: Free radical research 20040201

Title: Antioxidant and free radical scavenging activity of isoflavone metabolites.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20030901

Title: Evidence for the involvement of human liver microsomes CYP1A2 in the mono-hydroxylation of daidzein.

Journal: Clinica chimica acta; international journal of clinical chemistry 20030801

Title: Oxidative metabolism of the soy isoflavones daidzein and genistein in humans in vitro and in vivo.

Journal: Journal of agricultural and food chemistry 20010601

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Tags:75187-63-2 Molecular Formula|75187-63-2 MDL|75187-63-2 SMILES|75187-63-2 7,8-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-one