Title: In vitro characterization of zebrafish (Danio rerio) organic anion transporters Oat2a-e.
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Title: Structural-Activity Relationship of Ginsenosides from Steamed Ginseng in the Treatment of Erectile Dysfunction.
Journal: The American journal of Chinese medicine 20180101
Title: Angiotensin-(1-7) Downregulates Diabetes-Induced cGMP Phosphodiesterase Activation in Rat Corpus Cavernosum.
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Title: α1-A680T variant in GUCY1A3 as a candidate conferring protection from pulmonary hypertension among Kyrgyz highlanders.
Journal: Circulation. Cardiovascular genetics 20141201
Title: Erythropoietin prevents endothelial dysfunction in GTP-cyclohydrolase I-deficient hph1 mice.
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Title: Erythropoietin increases bioavailability of tetrahydrobiopterin and protects cerebral microvasculature against oxidative stress induced by eNOS uncoupling.
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Title: Dysfunctional nitric oxide signalling increases risk of myocardial infarction.
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Title: Uncoupling of eNOS causes superoxide anion production and impairs NO signaling in the cerebral microvessels of hph-1 mice.
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Title: Differential regulation by cyclic nucleotides of the CNGA4 and CNGB1b subunits in olfactory cyclic nucleotide-gated channels.
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Title: Cobinamides are novel coactivators of nitric oxide receptor that target soluble guanylyl cyclase catalytic domain.
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Title: Phosphodiesterase-5 inhibitor and rat lung ischemia-reperfusion injury.
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Title: Simultaneous LC-MS/MS analysis of the biomarkers cAMP and cGMP in plasma, CSF and brain tissue.
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Title: CSF concentrations of cAMP and cGMP are lower in patients with Creutzfeldt-Jakob disease but not Parkinson's disease and amyotrophic lateral sclerosis.
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Title: Differential effects of eNOS uncoupling on conduit and small arteries in GTP-cyclohydrolase I-deficient hph-1 mice.
Journal: American journal of physiology. Heart and circulatory physiology 20111201
Title: Anti-proliferative effect of curcumin on melanoma cells is mediated by PDE1A inhibition that regulates the epigenetic integrator UHRF1.
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Title: eNOS activation mediated by AMPK after stimulation of endothelial cells with histamine or thrombin is dependent on LKB1.
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Title: Testosterone-induced modulation of nitric oxide-cGMP signaling pathway and androgenesis in the rat Leydig cells.
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Title: Pyridoxine improves platelet nitric oxide synthase dysfunction induced by advanced glycation end products in vitro.
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Title: Linaclotide is a potent and selective guanylate cyclase C agonist that elicits pharmacological effects locally in the gastrointestinal tract.
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Title: Nitric oxide sensitive guanylyl cyclase activity decreases during cerebral postnatal development because of a reduction in heterodimerization.
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Title: Nitric oxide and carbon monoxide act as inhibitory neurotransmitters in the longitudinal muscle of C57BL/6J mouse distal colon.
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Title: Role of guanylate cyclase modulators in decompensated heart failure.
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Title: Decreased platelet nitric oxide contributes to increased circulating monocyte-platelet aggregates in hypertension.
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Title: Exploiting cGMP-based therapies for the prevention of left ventricular hypertrophy: NO* and beyond.
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Title: Anxiolytic effects of phosphodiesterase-2 inhibitors associated with increased cGMP signaling.
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Title: Pyridoxine increases nitric oxide biosynthesis in human platelets.
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Title: cGMP-dependent protein kinase type I is implicated in the regulation of the timing and quality of sleep and wakefulness.
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Title: Up-regulation of 3'5'-cyclic guanosine monophosphate-specific phosphodiesterase in the porcine cumulus-oocyte complex affects steroidogenesis during in vitro maturation.
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Title: Manganese potentiates nuclear factor-kappaB-dependent expression of nitric oxide synthase 2 in astrocytes by activating soluble guanylate cyclase and extracellular responsive kinase signaling pathways.
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Title: Ammonia inhibits the C-type natriuretic peptide-dependent cyclic GMP synthesis and calcium accumulation in a rat brain endothelial cell line.
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Title: The effect of sildenafil on ocular blood flow.
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Title: Role of cGMP-dependent protein kinase in development of tolerance to nitroglycerine in porcine coronary arteries.
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Title: Low nitric oxide: a key factor underlying copper-deficiency teratogenicity.
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Title: Hyperammonemia inhibits the natriuretic peptide receptor 2 (NPR-2)-mediated cyclic GMP synthesis in the astrocytic compartment of rat cerebral cortex slices.
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Title: Regulation of cGMP-dependent protein kinase-mediated vasodilation by hypoxia-induced reactive species in ovine fetal pulmonary veins.
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Title: Decrease in endogenous CGRP release in nitroglycerin tolerance: role of ALDH-2.
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Title: Chronic nitrates blunt the effects of not only nitric oxide but also natriuretic peptides in cardiac myocytes.
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Title: Effect of manganese on luteinizing hormone-releasing hormone secretion in adult male rats.
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Title: Manganese stimulates luteinizing hormone releasing hormone secretion in prepubertal female rats: hypothalamic site and mechanism of action.
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Title: Gene transfer of neuronal nitric oxide synthase into intracardiac Ganglia reverses vagal impairment in hypertensive rats.
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Title: The involvement of the nitric oxide in the effects and expression of opioid receptors during peripheral inflammation.
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Title: Atrial natriuretic peptide and long acting natriuretic peptide inhibit MEK 1/2 activation in human prostate cancer cells.
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Title: Inhibition of proinflammatory tumor necrosis factor-{alpha}-induced inducible nitric-oxide synthase by xanthine-based 7-[2-[4-(2-chlorobenzene)piperazinyl]ethyl]-1,3-dimethylxanthine (KMUP-1) and 7-[2-[4-(4-nitrobenzene)piperazinyl]ethyl]-1, 3-dimethylxanthine (KMUP-3) in rat trachea: The involvement of soluble guanylate cyclase and protein kinase G.
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Title: Synthesis, ocular effects, and nitric oxide donation of imidazole amidoximes.
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Title: Ramipril treatment protects against nitrate-induced oxidative stress in eNOS-/- mice: An implication of the NADPH oxidase pathway.
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Title: Role of probucol on endothelial dysfunction of epicardial coronary arteries associated with left ventricular hypertrophy.
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Title: Cyclic nucleotides modulate genioglossus and hypoglossal responses to excitatory inputs in rats.
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Title: Possible involvement of the spinal nitric oxide/cGMP pathway in vincristine-induced painful neuropathy in mice.
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Title: Modulatory effects of plant phenols on human multidrug-resistance proteins 1, 4 and 5 (ABCC1, 4 and 5).
Journal: The FEBS journal 20050901
Title: Adrenomedullin induces heme oxygenase-1 gene expression and cGMP formation in rat vascular smooth muscle cells.
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Title: Heme oxygenase-2 protects against glutathione depletion-induced neuronal apoptosis mediated by bilirubin and cyclic GMP.
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Title: Inhibitory effects on human eosinophil chemotaxis in vitro by BAY 41-2272, an activator of nitric oxide-independent site of soluble guanylate cyclase.
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Title: Distribution of cGMP-dependent protein kinase type I and its isoforms in the mouse brain and retina.
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Title: Effects of chronic endothelin ET(A) receptor blockade on blood pressure and vascular formation of cyclic guanosine-3',5'-monophosphate in spontaneously hypertensive rats.
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Title: Nitric oxide-cyclic GMP pathway with some emphasis on cavernosal contractility.
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Title: Inhibition of endothelial nitric oxide generation by low-density lipoprotein is partially prevented by L-arginine and L-ascorbate.
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Title: Role of nitric oxide in NAG-ST induced store-operated calcium entry in rat intestinal epithelial cells.
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Title: Localization of the NO-cGMP signaling pathway molecules, NOS III-phosphorylation sites, ERK1/2, and Akt/PKB in osteoclasts.
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Title: Cooperation between aspirin-triggered lipoxin and nitric oxide (NO) mediates antiadhesive properties of 2-(Acetyloxy)benzoic acid 3-(nitrooxymethyl)phenyl ester (NCX-4016) (NO-aspirin) on neutrophil-endothelial cell adherence.
Journal: The Journal of pharmacology and experimental therapeutics 20040601
Title: Antibodies to guanosine triphosphate misidentified as anti-double-stranded DNA antibodies in a patient with antinuclear antibody-negative lupus, due to buckling of insolubilized assay DNA.
Journal: Arthritis and rheumatism 20040501
Title: Gene transfer of endothelial NO synthase, but not eNOS plus inducible NOS, regressed atherosclerosis in rabbits.
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Title: Role of cyclic GMP on inhibition by nitric oxide donors of human eosinophil chemotaxis in vitro.
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Title: Intraplatelet cyclic guanosine-3',5'-monophosphate levels during pregnancy and preeclampsia.
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Title: Natriuretic peptides--a class of heterologous molecules in plants.
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Title: Nitric oxide-induced inhibition of aortic smooth muscle cell motility: role of PTP-PEST and adaptor proteins p130cas and Crk.
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Title: Transduction of the liver with activated Akt normalizes portal pressure in cirrhotic rats.
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Title: Functionally important calmodulin-binding sites in both NH2- and COOH-terminal regions of the cone photoreceptor cyclic nucleotide-gated channel CNGB3 subunit.
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Title: NO inhibits Na+-K+-2Cl- cotransport via a cytochrome P-450-dependent pathway in renal epithelial cells (MMDD1).
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Title: Phosphodiesterase inhibitors are neuroprotective to cultured spinal motor neurons.
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Title: Impairment of vascular and platelet levels of nitric oxide and cyclic guanosine-3',5'-monophosphate in cyclosporin A-induced hypertensive rats.
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Title: Regulation of endothelin-converting enzyme 1 in nephrotic syndrome in rats.
Journal: Nephron. Experimental nephrology 20030101
Title: Nitric oxide preferentially induces type 1 T cell differentiation by selectively up-regulating IL-12 receptor beta 2 expression via cGMP.
Journal: Proceedings of the National Academy of Sciences of the United States of America 20021210
Title: Rod cyclic nucleotide-gated channels have a stoichiometry of three CNGA1 subunits and one CNGB1 subunit.
Journal: Neuron 20021205
Title: Naphazoline-induced neuroendocrine changes: increases in ANP and cGMP levels, but suppression of NE, 3H-NE, and cAMP levels in rabbit eyes.
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Title: The MRP4/ABCC4 gene encodes a novel apical organic anion transporter in human kidney proximal tubules: putative efflux pump for urinary cAMP and cGMP.
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Title: Possible involvement of nitric oxide in signaling pigment dispersion in teleostean melanophores.
Journal: Zoological science 20011201
Title: L-citrulline mediated relaxation in the control and lipopolysaccharide-treated rat aortic rings.
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Title: Upregulation of phosphodiesterase 1A1 expression is associated with the development of nitrate tolerance.
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Title: Plasma levels of cyclic guanosine-3',5'-monophosphate in the cavernous and systemic blood of healthy males during different functional conditions of the penis.
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Title: Halothane but not isoflurane attenuates interleukin 1beta-induced nitric oxide synthase in vascular smooth muscle.
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Title: Electrophysiological characteristics of rat gustatory cyclic nucleotide--gated channel expressed in Xenopus oocytes.
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Title: Adeno-associated virus-mediated transfer of endothelial nitric oxide synthase gene inhibits protein synthesis of rat ventricular cardiomyocytes.
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Title: Nitric oxide metabolites, prostaglandins and trigeminal vasoactive peptides in internal jugular vein blood during spontaneous migraine attacks.
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Title: Cyclic GMP mediates apoptosis induced by sulindac derivatives via activation of c-Jun NH2-terminal kinase 1.
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Title: Molecular cloning and characterization of a distinct human phosphodiesterase gene family: PDE11A.
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Title: Cloning and characterization of a novel human phosphodiesterase that hydrolyzes both cAMP and cGMP (PDE10A).
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Title: Molecular cloning and characterization of human PDE8B, a novel thyroid-specific isozyme of 3',5'-cyclic nucleotide phosphodiesterase.
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Title: Cloning, chromosomal localization and functional expression of the gene encoding the alpha-subunit of the cGMP-gated channel in human cone photoreceptors.
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Title: Molecular cloning, functional expression and chromosomal localization of a human homolog of the cyclic nucleotide-gated ion channel of retinal cone photoreceptors.
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Title: Heteromeric olfactory cyclic nucleotide-gated channels: a subunit that confers increased sensitivity to cAMP.
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Title: Isolation and characterization of a previously undetected human cAMP phosphodiesterase by complementation of cAMP phosphodiesterase-deficient Saccharomyces cerevisiae.
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Title: Mechanisms of sodium retention in heart failure: relation to the renin-angiotensin-aldosterone system.
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