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Home Other Building Blocks 778277-15-9
778277-15-9,MFCD16877246
Catalog No.:AA00G3LN

778277-15-9 | GNF-5

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
98%
in stock  
$9.00   $7.00
- +
10mg
98%
in stock  
$18.00   $13.00
- +
100mg
98%
in stock  
$131.00   $92.00
- +
  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00G3LN
Chemical Name:
GNF-5
CAS Number:
778277-15-9
Molecular Formula:
C20H17F3N4O3
Molecular Weight:
418.3692
MDL Number:
MFCD16877246
SMILES:
OCCNC(=O)c1cccc(c1)c1ncnc(c1)Nc1ccc(cc1)OC(F)(F)F
Properties
Computed Properties
 
Complexity:
544  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
30  
Hydrogen Bond Acceptor Count:
9  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
7  
XLogP3:
3.5  

Upstream Synthesis Route

[1]JournalofMedicinalChemistry,2010,vol.53,#19,p.6934-6946

[1]Patent:US2011/21524,2011,A1,

Literature

Title: Expanding the diversity of allosteric bcr-abl inhibitors.

Journal: Journal of medicinal chemistry 20101014

Title: Targeting Bcr-Abl by combining allosteric with ATP-binding-site inhibitors.

Journal: Nature 20100128

Title: Allosteric inhibitors of Bcr-abl-dependent cell proliferation.

Journal: Nature chemical biology 20060201

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SDS
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