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79-62-9,MFCD00271492
Catalog No.:AA00G4AD

79-62-9 | DIHYDROLANOSTEROL

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25mg
95%
in stock  
$224.00   $157.00
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100mg
95%
in stock  
$568.00   $398.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00G4AD
Chemical Name:
DIHYDROLANOSTEROL
CAS Number:
79-62-9
Molecular Formula:
C30H52O
Molecular Weight:
428.7333
MDL Number:
MFCD00271492
SMILES:
CC(CCC[C@H]([C@H]1CC[C@@]2([C@]1(C)CCC1=C2CC[C@@H]2[C@]1(C)CC[C@@H](C2(C)C)O)C)C)C
Properties
Computed Properties
 
Complexity:
716  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
7  
Heavy Atom Count:
31  
Hydrogen Bond Acceptor Count:
1  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
5  
XLogP3:
9.4  

Literature

Title: New Bioactive Semisynthetic Derivatives of 31-Norlanostenol and Obtusifoliol from Euphorbia officinarum.

Journal: Natural product communications 20160601

Title: Targeting C4-demethylating genes in the cholesterol pathway sensitizes cancer cells to EGF receptor inhibitors via increased EGF receptor degradation.

Journal: Cancer discovery 20130101

Title: Mouse knockout of the cholesterogenic cytochrome P450 lanosterol 14alpha-demethylase (Cyp51) resembles Antley-Bixler syndrome.

Journal: The Journal of biological chemistry 20110819

Title: Circadian rhythm of cholesterol synthesis in mouse liver: a statistical analysis of the post-squalene metabolites in wild-type and Crem-knock-out mice.

Journal: Biochemical and biophysical research communications 20110520

Title: Expression, purification, and characterization of Aspergillus fumigatus sterol 14-alpha demethylase (CYP51) isoenzymes A and B.

Journal: Antimicrobial agents and chemotherapy 20101001

Title: Effects of FoxO4 overexpression on cholesterol biosynthesis, triacylglycerol accumulation, and glucose uptake.

Journal: Journal of lipid research 20100601

Title: Antibacterial compounds from mushrooms I: a lanostane-type triterpene and prenylphenol derivatives from Jahnoporus hirtus and Albatrellus flettii and their activities against Bacillus cereus and Enterococcus faecalis.

Journal: Planta medica 20100201

Title: Trypanosoma cruzi CYP51 inhibitor derived from a Mycobacterium tuberculosis screen hit.

Journal: PLoS neglected tropical diseases 20090201

Title: Cholesterol, lanosterol, and ergosterol attenuate the membrane association of LL-37(W27F) and temporin L.

Journal: Biochimica et biophysica acta 20080601

Title: Effectors of rapid homeostatic responses of endoplasmic reticulum cholesterol and 3-hydroxy-3-methylglutaryl-CoA reductase.

Journal: The Journal of biological chemistry 20080118

Title: Hypoxia stimulates degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase through accumulation of lanosterol and hypoxia-inducible factor-mediated induction of insigs.

Journal: The Journal of biological chemistry 20070914

Title: A low-toxicity method for the separation of lanosterol and dihydrolanosterol from commercial mixtures.

Journal: Steroids 20040901

Title: Cholesterol-lowering properties of Ganoderma lucidum in vitro, ex vivo, and in hamsters and minipigs.

Journal: Lipids in health and disease 20040101

Title: Creating new supramolecular materials by architecture of three-dimensional nanocrystal fiber networks.

Journal: Journal of the American Chemical Society 20021218

Title: The role of cytochrome P450 in the regulation of cholesterol biosynthesis.

Journal: Lipids 20021201

Title: Selective inhibition of mammalian lanosterol 14 alpha-demethylase by RS-21607 in vitro and in vivo.

Journal: Biochemistry 19940419

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Tags:79-62-9 Molecular Formula|79-62-9 MDL|79-62-9 SMILES|79-62-9 DIHYDROLANOSTEROL