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Title: New Bioactive Semisynthetic Derivatives of 31-Norlanostenol and Obtusifoliol from Euphorbia officinarum.
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Title: Lanosterol biosynthesis: the critical role of the methyl-29 group of 2,3-oxidosqualene for the correct folding of this substrate and for the construction of the five-membered D ring.
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Title: Cloning of the lanosterol 14-α-demethylase ( ERG11 ) gene in Trichosporon asahii: a possible association between G453R amino acid substitution and azole resistance in T. asahii.
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Title: Evolutionarily conserved Delta(25(27))-olefin ergosterol biosynthesis pathway in the alga Chlamydomonas reinhardtii.
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Title: Hepatitis C virus selectively perturbs the distal cholesterol synthesis pathway in a genotype-specific manner.
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Title: A comprehensive method for extraction and quantitative analysis of sterols and secosteroids from human plasma.
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Title: Substrate analog studies of the ω-regiospecificity of Mycobacterium tuberculosis cholesterol metabolizing cytochrome P450 enzymes CYP124A1, CYP125A1 and CYP142A1.
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Title: Potential biological functions of cytochrome P450 reductase-dependent enzymes in small intestine: novel link to expression of major histocompatibility complex class II genes.
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Title: HILIC quantification of oenotheralanosterol A and B from Oenothera biennis and their suppression of IL-6 and TNF-α expression in mouse macrophages.
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Title: 27-Hydroxycholesterol, does it exist? On the nomenclature and stereochemistry of 26-hydroxylated sterols.
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Title: [Triterpenoids from Inonotus obliquus protect mice against oxidative damage induced by CCl4].
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Title: Cytotoxic and pro-apoptotic effects of novel ganoderic acid derivatives on human cervical cancer cells in vitro.
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Title: Novel sterol metabolic network of Trypanosoma brucei procyclic and bloodstream forms.
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Title: Cell-cell transmission enables HIV-1 to evade inhibition by potent CD4bs directed antibodies.
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Title: Simultaneous determination of cimicifugoside H-2, cimicifugoside H-1, 23-epi-26-deoxyactein, cimigenol xyloside and 25-O-acetylcimigenoside in beagle dog plasma by LC-MS/MS.
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Title: Lanosterol induces mitochondrial uncoupling and protects dopaminergic neurons from cell death in a model for Parkinson's disease.
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Title: Enhanced recovery of antitumor ganoderic acid T from Ganoderma lucidum mycelia by novel chemical conversion strategy.
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Title: Characterization of the chromosome 4 genes that affect fluconazole-induced disomy formation in Cryptococcus neoformans.
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Title: CUP-1 is a novel protein involved in dietary cholesterol uptake in Caenorhabditis elegans.
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Title: Endoplasmic Reticulum Stress-Associated Lipid Droplet Formation and Type II Diabetes.
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Title: Sequence and analysis of the genome of the pathogenic yeast Candida orthopsilosis.
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Title: Identification and characterization of antifungal compounds using a Saccharomyces cerevisiae reporter bioassay.
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Title: Propiconazole is a specific and accessible brassinosteroid (BR) biosynthesis inhibitor for Arabidopsis and maize.
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Title: The effect of ketoconazole on post-burn inflammation, hypermetabolism and clinical outcomes.
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Title: Sterol lipid metabolism in down syndrome revisited: down syndrome is associated with a selective reduction in serum brassicasterol levels.
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Title: Lipidomic analysis of extracellular vesicles from the pathogenic phase of Paracoccidioides brasiliensis.
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Title: Enhanced production of ganoderic acids and cytotoxicity of Ganoderma lucidum using solid-medium culture.
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Title: The yeast ABC transporter Pdr18 (ORF YNR070w) controls plasma membrane sterol composition, playing a role in multidrug resistance.
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Title: Semisynthesis and biological evaluation of ganodermanontriol and its stereoisomeric triols.
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Title: Transitional forms between the three domains of life and evolutionary implications.
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Title: Ganodermanontriol (GDNT) exerts its effect on growth and invasiveness of breast cancer cells through the down-regulation of CDC20 and uPA.
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Title: Synthesis, antifungal activity, and docking study of some new 1,2,4-triazole analogs.
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Title: Pathogenesis-based therapy reverses cutaneous abnormalities in an inherited disorder of distal cholesterol metabolism.
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Title: Deletion of Cryptococcus neoformans AIF ortholog promotes chromosome aneuploidy and fluconazole-resistance in a metacaspase-independent manner.
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Title: Triterpenoids with neurotrophic activity from Ganoderma lucidum.
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Title: Do the substituent effects affect conformational freedom of squalene in hopene biosynthesis?
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Title: Cholesterol metabolism is required for intracellular hedgehog signal transduction in vivo.
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Title: N-Cyclo-propyl-N-[2-(2,4-difluoro-phen-yl)-2-hy-droxy-1-(1H-1,2,4-triazol-1-yl)prop-yl]-2-(5-methyl-2,4-dioxo-1,2,3,4-tetra-hydro-pyrimidin-1-yl)acetamide dichloro-methane 0.62-solvate.
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Title: Mouse knockout of the cholesterogenic cytochrome P450 lanosterol 14alpha-demethylase (Cyp51) resembles Antley-Bixler syndrome.
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Title: Structure-based design, synthesis, and antifungal activity of new triazole derivatives.
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Title: Synthesis, in vitro evaluation and molecular docking studies of new triazole derivatives as antifungal agents.
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Title: Design, synthesis and antifungal activities of novel 1,2,4-triazole derivatives.
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Title: p53 is important for the anti-invasion of ganoderic acid T in human carcinoma cells.
Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20110615
Title: Cerebral accumulation of dietary derivable plant sterols does not interfere with memory and anxiety related behavior in Abcg5-/- mice.
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Title: The potentiality of medicinal plants as the source of new contraceptive principles in males.
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Title: Triterpene cyclases from Oryza sativa L.: cycloartenol, parkeol and achilleol B synthases.
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Title: Whole body cholesterol metabolism is impaired in Huntington's disease.
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Title: Epigenetic alterations in liver of C57BL/6J mice after short-term inhalational exposure to 1,3-butadiene.
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Title: Heterologous expression and characterization of the sterol 14α-demethylase CYP51F1 from Candida albicans.
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Title: Cdr2p contributes to fluconazole resistance in Candida dubliniensis clinical isolates.
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Title: Cosegregation of aortic root atherosclerosis and intermediate lipid phenotypes on chromosomes 2 and 8 in an intercross of C57BL/6 and BALBc/ByJ low-density lipoprotein receptor-/- mice.
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Title: [Studies on the secondary metabolites of Coriolopsis sp. G066].
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Title: Sensitive and selective liquid chromatography-tandem mass spectrometry method for the determination of five ganoderic acids in Ganoderma lucidum and its related species.
Journal: Journal of pharmaceutical and biomedical analysis 20110325
Title: Pubertal presentation in seven patients with congenital adrenal hyperplasia due to P450 oxidoreductase deficiency.
Journal: The Journal of clinical endocrinology and metabolism 20110301
Title: Ganodermanontriol, a lanostanoid triterpene from Ganoderma lucidum, suppresses growth of colon cancer cells through ß-catenin signaling.
Journal: International journal of oncology 20110301
Title: Effects of inotodiol extracts from inonotus obliquus on proliferation cycle and apoptotic gene of human lung adenocarcinoma cell line A549.
Journal: Chinese journal of integrative medicine 20110301
Title: Mutation of isoleucine 705 of the oxidosqualene-lanosterol cyclase from Saccharomyces cerevisiae affects lanosterol's C/D-ring cyclization and 17α/β-exocyclic side chain stereochemistry.
Journal: Organic & biomolecular chemistry 20110221
Title: Autoregulation of cholesterol synthesis: physiologic and pathophysiologic consequences.
Journal: Steroids 20110201
Title: Functional expression and characterization of CYP51 from dandruff-causing Malassezia globosa.
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Title: Friedolanostane, friedocycloartane and benzophenone constituents of the bark and leaves of Garcinia benthami.
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Title: Ultrastructural alterations induced by Δ(24(25))-sterol methyltransferase inhibitors on Trichomonas vaginalis.
Journal: FEMS microbiology letters 20110201
Title: Molecular modeling of human lanosterol 14α-demethylase complexes with substrates and their derivatives.
Journal: Biochemistry. Biokhimiia 20110201
Title: Cytosolic NADPH balancing in Penicillium chrysogenum cultivated on mixtures of glucose and ethanol.
Journal: Applied microbiology and biotechnology 20110101
Title: Inhibition of human sterol Δ7-reductase and other postlanosterol enzymes by LK-980, a novel inhibitor of cholesterol synthesis.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20110101
Title: Two oxidosqualene cyclases responsible for biosynthesis of tomato fruit cuticular triterpenoids.
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Title: The evolution of farnesoid X, vitamin D, and pregnane X receptors: insights from the green-spotted pufferfish (Tetraodon nigriviridis) and other non-mammalian species.
Journal: BMC biochemistry 20110101
Title: Genome variation in Cryptococcus gattii, an emerging pathogen of immunocompetent hosts.
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Title: Evaluation of the antibacterial and anticancer activities of some South African medicinal plants.
Journal: BMC complementary and alternative medicine 20110101
Title: Development of proteomics-based fungicides: new strategies for environmentally friendly control of fungal plant diseases.
Journal: International journal of molecular sciences 20110101
Title: Lipid pathway alterations in Parkinson's disease primary visual cortex.
Journal: PloS one 20110101
Title: The thermodynamics of simple biomembrane mimetic systems.
Journal: Journal of pharmacy & bioallied sciences 20110101
Title: Rapid isolation and purification of inotodiol and trametenolic acid from Inonotus obliquus by high-speed counter-current chromatography with evaporative light scatting detection.
Journal: Phytochemical analysis : PCA 20110101
Title: Pharmacology and metabolism of voriconazole and Posaconazole in the treatment of invasive aspergillosis: review of the literature.
Journal: European journal of medical research 20110101
Title: Epidemiology and antifungal resistance in invasive Aspergillosis according to primary disease: review of the literature.
Journal: European journal of medical research 20110101
Title: Impacts of membrane biophysics in Alzheimer's disease: from amyloid precursor protein processing to aβ Peptide-induced membrane changes.
Journal: International journal of Alzheimer's disease 20110101
Title: Comparative lipidomics of azole sensitive and resistant clinical isolates of Candida albicans reveals unexpected diversity in molecular lipid imprints.
Journal: PloS one 20110101
Title: Pneumocystis carinii sterol 14α-demethylase activity in Saccharomyces cerevisiae erg11 knockout mutant: sterol biochemistry.
Journal: The Journal of eukaryotic microbiology 20110101
Title: Expanding a dynamic flux balance model of yeast fermentation to genome-scale.
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Title: Role of heme and heme-proteins in trypanosomatid essential metabolic pathways.
Journal: Enzyme research 20110101
Title: Synthesis, in vitro antifungal activity and mechanism of action of four sterol hydrazone analogues against the dimorphic fungus Paracoccidioides brasiliensis.
Journal: Steroids 20110101
Title: Cross-species discovery of syncretic drug combinations that potentiate the antifungal fluconazole.
Journal: Molecular systems biology 20110101
Title: Update on the optimal use of voriconazole for invasive fungal infections.
Journal: Infection and drug resistance 20110101
Title: Pathogenesis of the cutaneous phenotype in inherited disorders of cholesterol metabolism: Therapeutic implications for topical treatment of these disorders.
Journal: Dermato-endocrinology 20110101
Title: Amino acid substitutions at the major insertion loop of Candida albicans sterol 14alpha-demethylase are involved in fluconazole resistance.
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Title: Molecular modelling of the emergence of azole resistance in Mycosphaerella graminicola.
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Title: Multiple oxygen tension environments reveal diverse patterns of transcriptional regulation in primary astrocytes.
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Title: Characterization of the channel constriction allowing the access of the substrate to the active site of yeast oxidosqualene cyclase.
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Title: Metabolic alteration of urinary steroids in pre- and post-menopausal women, and men with papillary thyroid carcinoma.
Journal: BMC cancer 20110101
Title: Next generation sequencing provides rapid access to the genome of Puccinia striiformis f. sp. tritici, the causal agent of wheat stripe rust.
Journal: PloS one 20110101
Title: Analysis of hypoxia and hypoxia-like states through metabolite profiling.
Journal: PloS one 20110101
Title: TIGER: Toolbox for integrating genome-scale metabolic models, expression data, and transcriptional regulatory networks.
Journal: BMC systems biology 20110101
Title: The role of Candida albicans homologous recombination factors Rad54 and Rdh54 in DNA damage sensitivity.
Journal: BMC microbiology 20110101
Title: Synergistic inhibition of endothelial cell proliferation, tube formation, and sprouting by cyclosporin A and itraconazole.
Journal: PloS one 20110101
Title: Mechanism of resistance to dietary cholesterol.
Journal: Journal of lipids 20110101
Title: Genome-wide linkage scan of a pedigree with familial hypercholesterolemia suggests susceptibility loci on chromosomes 3q25-26 and 21q22.
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Title: Enteric microbiome metabolites correlate with response to simvastatin treatment.
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Title: Protein trafficking, ergosterol biosynthesis and membrane physics impact recombinant protein secretion in Pichia pastoris.
Journal: Microbial cell factories 20110101
Title: Preventive and therapeutic euphol treatment attenuates experimental colitis in mice.
Journal: PloS one 20110101
Title: Mono-(2-ethylhexyl) phthalate directly alters the expression of Leydig cell genes and CYP17 lyase activity in cultured rat fetal testis.
Journal: PloS one 20110101
Title: Oral itraconazole for the treatment of severe seborrhoeic dermatitis.
Journal: Indian journal of dermatology 20110101
Title: In vitro antitumor activity and structure characterization of ethanol extracts from wild and cultivated Chaga medicinal mushroom, Inonotus obliquus (Pers.:Fr.) Pilát (Aphyllophoromycetideae).
Journal: International journal of medicinal mushrooms 20110101
Title: Mathematical modeling and validation of the ergosterol pathway in Saccharomyces cerevisiae.
Journal: PloS one 20110101
Title: Triterpenoid biosynthesis and engineering in plants.
Journal: Frontiers in plant science 20110101
Title: Bioactivity-guided isolation of GABA(A) receptor modulating constituents from the rhizomes of Actaea racemosa.
Journal: Journal of natural products 20101227
Title: Separation and determination of four ganoderic acids from dried fermentation mycelia powder of Ganoderma lucidum by capillary zone electrophoresis.
Journal: Journal of pharmaceutical and biomedical analysis 20101215
Title: Current progress in the study on biosynthesis and regulation of ganoderic acids.
Journal: Applied microbiology and biotechnology 20101201
Title: Impact of atorvastatin and omega-3 ethyl esters 90 on plasma plant sterol concentrations and cholesterol synthesis in type 2 diabetes: a randomised placebo controlled factorial trial.
Journal: Atherosclerosis 20101201
Title: Biochemical research elucidating metabolic pathways in Pneumocystis.
Journal: Parasite (Paris, France) 20101201
Title: Divergent interactions involving the oxidosqualene cyclase and the steroid-3-ketoreductase in the sterol biosynthetic pathway of mammals and yeasts.
Journal: Biochimica et biophysica acta 20101101
Title: Hair and skin sterols in normal mice and those with deficient dehydrosterol reductase (DHCR7), the enzyme associated with Smith-Lemli-Opitz syndrome.
Journal: The Journal of steroid biochemistry and molecular biology 20101101
Title: Significance of protein elicitor isolated from Tuber melanosporum on the production of ganoderic acid and Ganoderma polysaccharides during the fermentation of Ganoderma lucidum.
Journal: Bioprocess and biosystems engineering 20101001
Title: Inhibition of aldose reductase in vitro by constituents of Ganoderma lucidum.
Journal: Planta medica 20101001
Title: Cloning, mechanistic and functional analysis of a fungal sterol C24-methyltransferase implicated in brassicasterol biosynthesis.
Journal: Biochimica et biophysica acta 20101001
Title: Expression, purification, and characterization of Aspergillus fumigatus sterol 14-alpha demethylase (CYP51) isoenzymes A and B.
Journal: Antimicrobial agents and chemotherapy 20101001
Title: An unusual lanostane-type triterpenoid, spiroinonotsuoxodiol, and other triterpenoids from Inonotus obliquus.
Journal: Phytochemistry 20101001
Title: Targeting inflammatory pathways by triterpenoids for prevention and treatment of cancer.
Journal: Toxins 20101001
Title: Methyl jasmonate induces ganoderic acid biosynthesis in the basidiomycetous fungus Ganoderma lucidum.
Journal: Bioresource technology 20100901
Title: Observations on squalene accumulation in Saccharomyces cerevisiae due to the manipulation of HMG2 and ERG6.
Journal: FEMS yeast research 20100901
Title: Subcellular organelle lipidomics in TLR-4-activated macrophages.
Journal: Journal of lipid research 20100901
Title: Phytochemical investigation of the seeds of Althea officinalis L.
Journal: Natural product research 20100901
Title: Drug-induced regulation of target expression.
Journal: PLoS computational biology 20100901
Title: Azole drugs are imported by facilitated diffusion in Candida albicans and other pathogenic fungi.
Journal: PLoS pathogens 20100901
Title: Impact of oxygen level in gaseous phase on gene transcription and ganoderic acid biosynthesis in liquid static cultures of Ganoderma lucidum.
Journal: Bioprocess and biosystems engineering 20100801
Title: Adaptation of cholesterol synthesis to fasting and TNF-alpha: profiling cholesterol intermediates in the liver, brain, and testis.
Journal: The Journal of steroid biochemistry and molecular biology 20100801
Title: Alterations of cholesterol precursor levels in Alzheimer's disease.
Journal: Biochimica et biophysica acta 20100801
Title: A new ganoderic acid from Ganoderma lucidum mycelia.
Journal: Journal of Asian natural products research 20100801
Title: PKC signaling regulates drug resistance of the fungal pathogen Candida albicans via circuitry comprised of Mkc1, calcineurin, and Hsp90.
Journal: PLoS pathogens 20100801
Title: [Studies on the chemical constituents from the antithrombus activity extract of Radix Aerio Fici Microcarpae].
Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20100801
Title: Abiesatrines A-J: anti-inflammatory and antitumor triterpenoids from Abies georgei Orr.
Journal: Organic & biomolecular chemistry 20100607
Title: Effects of FoxO4 overexpression on cholesterol biosynthesis, triacylglycerol accumulation, and glucose uptake.
Journal: Journal of lipid research 20100601
Title: Gonadotropin-regulated expressions of lanosterol 14alpha-demethylase, sterol Delta14-reductase and C-4 sterol methyl oxidase contribute to the accumulation of meiosis-activating sterol in rabbit gonads.
Journal: Prostaglandins & other lipid mediators 20100601
Title: The sterol methyltransferases SMT1, SMT2, and SMT3 influence Arabidopsis development through nonbrassinosteroid products.
Journal: Plant physiology 20100601
Title: Biotechnological production and application of ganoderic acids.
Journal: Applied microbiology and biotechnology 20100601
Title: Requirement for ergosterol in V-ATPase function underlies antifungal activity of azole drugs.
Journal: PLoS pathogens 20100601
Title: Anticancer activity of subfractions containing pure compounds of Chaga mushroom (Inonotus obliquus) extract in human cancer cells and in Balbc/c mice bearing Sarcoma-180 cells.
Journal: Nutrition research and practice 20100601
Title: Antiplasmodial lanostanes from the Ganoderma lucidum mushroom.
Journal: Journal of natural products 20100528
Title: Second generation analogues of the cancer drug clinical candidate tipifarnib for anti-Chagas disease drug discovery.
Journal: Journal of medicinal chemistry 20100527
Title: Identification of testosterone-dependent volatile compounds and proteins in the preputial gland of rat Rattus norvegicus.
Journal: General and comparative endocrinology 20100515
Title: Enhanced biosynthetic gene expressions and production of ganoderic acids in static liquid culture of Ganoderma lucidum under phenobarbital induction.
Journal: Applied microbiology and biotechnology 20100501
Title: Structure-based rational design, synthesis and antifungal activity of oxime-containing azole derivatives.
Journal: Bioorganic & medicinal chemistry letters 20100501
Title: Antifungal drug resistance: not all azoles are equal.
Journal: Expert review of anti-infective therapy 20100501
Title: Lipid metabolism and HCV infection.
Journal: Viruses 20100501
Title: Cloning and characterization of the lanosterol 14alpha-demethylase gene from Antrodia cinnamomea.
Journal: Journal of agricultural and food chemistry 20100428
Title: Lipotoxicity in obese pregnancy and its potential role in adverse pregnancy outcome and obesity in the offspring.
Journal: Clinical science (London, England : 1979) 20100428
Title: Structural elucidation of cisoid and transoid cyclization pathways of a sesquiterpene synthase using 2-fluorofarnesyl diphosphates.
Journal: ACS chemical biology 20100416
Title: Screening for amino acid substitutions in the Candida albicans Erg11 protein of azole-susceptible and azole-resistant clinical isolates: new substitutions and a review of the literature.
Journal: Diagnostic microbiology and infectious disease 20100401
Title: Structural characterization of CYP51 from Trypanosoma cruzi and Trypanosoma brucei bound to the antifungal drugs posaconazole and fluconazole.
Journal: PLoS neglected tropical diseases 20100401
Title: [RP-HPLC simultaneous determination of five triterpenoid acids in different parts of Poria cocos by UV wavelengths switch].
Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20100401
Title: Relationship between antifungal resistance of fluconazole resistant Candida albicans and mutations in ERG11 gene.
Journal: Chinese medical journal 20100305
Title: Improved model of lanosterol 14alpha-demethylase by ligand-supported homology modeling: validation by virtual screening and azole optimization.
Journal: ChemMedChem 20100301
Title: Lanostane triterpenes from the fruiting bodies of Ganoderma lucidum and their inhibitory effects on adipocyte differentiation in 3T3-L1 Cells.
Journal: Journal of natural products 20100226
Title: Effects of lanosterol on in vitro maturation of porcine oocytes.
Journal: Animal reproduction science 20100201
Title: Topical anti-inflammatory effect of tirucallol, a triterpene isolated from Euphorbia lactea latex.
Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20100201
Title: Antibacterial compounds from mushrooms I: a lanostane-type triterpene and prenylphenol derivatives from Jahnoporus hirtus and Albatrellus flettii and their activities against Bacillus cereus and Enterococcus faecalis.
Journal: Planta medica 20100201
Title: Ganoderic acids from Ganoderma lucidum: inhibitory activity of osteoclastic differentiation and structural criteria.
Journal: Planta medica 20100201
Title: Interactions of oxidosqualene cyclase (Erg7p) with 3-keto reductase (Erg27p) and other enzymes of sterol biosynthesis in yeast.
Journal: Biochimica et biophysica acta 20100201
Title: Reverse genetics in Candida albicans predicts ARF cycling is essential for drug resistance and virulence.
Journal: PLoS pathogens 20100201
Title: Phytochemical characteristics and hypoglycaemic activity of fraction from mushroom Inonotus obliquus.
Journal: Journal of the science of food and agriculture 20100130
Title: Production of individual ganoderic acids and expression of biosynthetic genes in liquid static and shaking cultures of Ganoderma lucidum.
Journal: Applied microbiology and biotechnology 20100101
Title: Cholesterol, non-cholesterol sterols and bile acids in paediatric gallstones.
Journal: Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20100101
Title: Evolution of ergosterol biosynthesis inhibitors as fungicidal against Candida.
Journal: Microbial pathogenesis 20100101
Title: Changes in cholesterol biosynthetic and transport pathways after excitotoxicity.
Journal: Journal of neurochemistry 20100101
Title: Functional characterization and localization of Pneumocystis carinii lanosterol synthase.
Journal: Eukaryotic cell 20100101
Title: Protostadienol synthase from Aspergillus fumigatus: functional conversion into lanosterol synthase.
Journal: Biochemical and biophysical research communications 20100101
Title: Vitamin d levels and lipid response to atorvastatin.
Journal: International journal of endocrinology 20100101
Title: Functional characterization of the Chlamydomonas reinhardtii ERG3 ortholog, a gene involved in the biosynthesis of ergosterol.
Journal: PloS one 20100101
Title: Origin of the cell nucleus, mitosis and sex: roles of intracellular coevolution.
Journal: Biology direct 20100101
Title: Chemogenomic and transcriptome analysis identifies mode of action of the chemosensitizing agent CTBT (7-chlorotetrazolo[5,1-c]benzo[1,2,4]triazine).
Journal: BMC genomics 20100101
Title: Identification and analysis of unitary pseudogenes: historic and contemporary gene losses in humans and other primates.
Journal: Genome biology 20100101
Title: Metabolomic analyses of plasma reveals new insights into asphyxia and resuscitation in pigs.
Journal: PloS one 20100101
Title: Anti-inflammatory effects of Inonotus obliquus in colitis induced by dextran sodium sulfate.
Journal: Journal of biomedicine & biotechnology 20100101
Title: Downregulation of genes with a function in axon outgrowth and synapse formation in motor neurones of the VEGFdelta/delta mouse model of amyotrophic lateral sclerosis.
Journal: BMC genomics 20100101
Title: Ganoderic acid T inhibits tumor invasion in vitro and in vivo through inhibition of MMP expression.
Journal: Pharmacological reports : PR 20100101
Title: Development of azole resistance in Aspergillus fumigatus during azole therapy associated with change in virulence.
Journal: PloS one 20100101
Title: De novo sequencing and analysis of the American ginseng root transcriptome using a GS FLX Titanium platform to discover putative genes involved in ginsenoside biosynthesis.
Journal: BMC genomics 20100101
Title: Clinical utility of voriconazole eye drops in ophthalmic fungal keratitis.
Journal: Clinical ophthalmology (Auckland, N.Z.) 20100101
Title: Cellular cholesterol delivery, intracellular processing and utilization for biosynthesis of steroid hormones.
Journal: Nutrition & metabolism 20100101
Title: Phylogenetic distribution of fungal sterols.
Journal: PloS one 20100101
Title: Chemical combinations elucidate pathway interactions and regulation relevant to Hepatitis C replication.
Journal: Molecular systems biology 20100101
Title: Structural and functional study of YER067W, a new protein involved in yeast metabolism control and drug resistance.
Journal: PloS one 20100101
Title: Cholesterol induces specific spatial and orientational order in cholesterol/phospholipid membranes.
Journal: PloS one 20100101
Title: Antagonistic changes in sensitivity to antifungal drugs by mutations of an important ABC transporter gene in a fungal pathogen.
Journal: PloS one 20100101
Title: Liposomal amphotericin B and leishmaniasis: dose and response.
Journal: Journal of global infectious diseases 20100101
Title: Inhibition of iron uptake is responsible for differential sensitivity to V-ATPase inhibitors in several cancer cell lines.
Journal: PloS one 20100101
Title: Candida albicans virulence and drug-resistance requires the O-acyltransferase Gup1p.
Journal: BMC microbiology 20100101
Title: Lipid mediators in acne.
Journal: Mediators of inflammation 20100101
Title: Surface lipids as multifunctional mediators of skin responses to environmental stimuli.
Journal: Mediators of inflammation 20100101
Title: Identification and developmental expression of the full complement of Cytochrome P450 genes in Zebrafish.
Journal: BMC genomics 20100101
Title: Development, clinical utility, and place in therapy of posaconazole for prevention and treatment of invasive fungal infections.
Journal: Drug design, development and therapy 20100101
Title: Direct electrochemical analyses of human cytochromes b5 with a mutated heme pocket showed a good correlation between their midpoint and half wave potentials.
Journal: Journal of biomedical science 20100101
Title: Clearance in vivo of instilled [h]cholesterol from the rat lung.
Journal: Biochemistry research international 20100101
Title: Tumor and reproductive traits are linked by RNA metabolism genes in the mouse ovary: a transcriptome-phenotype association analysis.
Journal: BMC genomics 20100101
Title: Deciphering the nuclear bile acid receptor FXR paradigm.
Journal: Nuclear receptor signaling 20100101
Title: Management of tinea capitis in childhood.
Journal: Clinical, cosmetic and investigational dermatology 20100101
Title: Amelioration of lead-induced hepatotoxicity by Allium sativum extracts in Swiss albino mice.
Journal: The Libyan journal of medicine 20100101
Title: Role of posaconazole in the treatment of oropharyngeal candidiasis.
Journal: Infection and drug resistance 20100101
Title: Optimal management of oropharyngeal and esophageal candidiasis in patients living with HIV infection.
Journal: HIV/AIDS (Auckland, N.Z.) 20100101
Title: Phytopharmacology of Ficus religiosa.
Journal: Pharmacognosy reviews 20100101
Title: Lanostanes from Phellinus igniarius and their iNOS inhibitory activities.
Journal: Planta medica 20091201
Title: 13C nuclear magnetic resonance data of lanosterol derivatives--profiling the steric topology of the steroid skeleton via substituent effects on its 13C NMR.
Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20091201
Title: Design, synthesis, and antifungal activity of novel conformationally restricted triazole derivatives.
Journal: Archiv der Pharmazie 20091201
Title: Development of a new method for improved identification and relative quantification of unknown metabolites in complex samples: determination of a triterpenoid metabolic fingerprint for the in situ characterization of Ganoderma bioactive compounds.
Journal: Journal of separation science 20091201
Title: 4beta-hydroxycholesterol as a marker of CYP3A4 inhibition in vivo - effects of itraconazole in man.
Journal: International journal of clinical pharmacology and therapeutics 20091201
Title: Steroidal triterpenes: design of substrate-based inhibitors of ergosterol and sitosterol synthesis.
Journal: Molecules (Basel, Switzerland) 20091118
Title: Inhibition of nucleoside transport and synergistic potentiation of methotrexate cytotoxicity by cimicifugoside, a triterpenoid from Cimicifuga simplex.
Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20091105
Title: Reducing CYP51 inhibits follicle-stimulating hormone induced resumption of mouse oocyte meiosis in vitro.
Journal: Journal of lipid research 20091101
Title: Initiation of steroidogenesis precedes expression of cholesterologenic enzymes in the fetal mouse testes.
Journal: Anatomia, histologia, embryologia 20091101
Title: Dehydroeburicoic acid induces calcium- and calpain-dependent necrosis in human U87MG glioblastomas.
Journal: Chemical research in toxicology 20091101
Title: 24-Ethyl,24-methyl-29-nor-lanostanes from leaves of Freycinetia formosana.
Journal: Chemical & pharmaceutical bulletin 20091101
Title: Quantitative determination of steroids in the fruiting bodies and submerged-cultured mycelia of Inonotus obliquus.
Journal: Se pu = Chinese journal of chromatography 20091101
Title: Discovery of potent and reversible monoacylglycerol lipase inhibitors.
Journal: Chemistry & biology 20091030
Title: Discovery of highly potent novel antifungal azoles by structure-based rational design.
Journal: Bioorganic & medicinal chemistry letters 20091015
Title: Plasma levels of 24S-hydroxycholesterol reflect brain volumes in patients without objective cognitive impairment but not in those with Alzheimer's disease.
Journal: Neuroscience letters 20091002
Title: New azoles with potent antifungal activity: design, synthesis and molecular docking.
Journal: European journal of medicinal chemistry 20091001
Title: Anti-tumor-promoting effects of 25-methoxyporicoic acid A and other triterpene acids from Poria cocos.
Journal: Journal of natural products 20091001
Title: Acquisition of aneuploidy provides increased fitness during the evolution of antifungal drug resistance.
Journal: PLoS genetics 20091001
Title: Inhibition of cholesterol biosynthesis disrupts lipid raft/caveolae and affects insulin receptor activation in 3T3-L1 preadipocytes.
Journal: Biochimica et biophysica acta 20090901
Title: A comparison of the packing behavior of egg phosphatidylcholine with cholesterol and biogenically related sterols in Langmuir monolayer films.
Journal: Chemistry and physics of lipids 20090901
Title: Effects of triterpenoids from Poria cocos Wolf on the serotonin type 3A receptor-mediated ion current in Xenopus oocytes.
Journal: European journal of pharmacology 20090801
Title: Hsp90 orchestrates stress response signaling governing fungal drug resistance.
Journal: PLoS pathogens 20090801
Title: Exploring the effects of sterols in model lipid membranes using single-molecule orientations.
Journal: The journal of physical chemistry. B 20090730
Title: Combined gas chromatographic/mass spectrometric analysis of cholesterol precursors and plant sterols in cultured cells.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20090715
Title: Metabolism and pharmacokinetics in rats of ganoderiol F, a highly cytotoxic and antitumor triterpene from Ganoderma lucidum.
Journal: Journal of natural medicines 20090701
Title: Genomic analysis of the basal lineage fungus Rhizopus oryzae reveals a whole-genome duplication.
Journal: PLoS genetics 20090701
Title: Frequency and evolution of Azole resistance in Aspergillus fumigatus associated with treatment failure.
Journal: Emerging infectious diseases 20090701
Title: Hsp90 governs echinocandin resistance in the pathogenic yeast Candida albicans via calcineurin.
Journal: PLoS pathogens 20090701
Title: A new triterpene from the fruiting bodies of Ganoderma lucidum.
Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20090701
Title: Structurally simple inhibitors of lanosterol 14alpha-demethylase are efficacious in a rodent model of acute Chagas disease.
Journal: Journal of medicinal chemistry 20090625
Title: Molecular oxygen activation and proton transfer mechanisms in lanosterol 14alpha-demethylase catalysis.
Journal: The journal of physical chemistry. B 20090611
Title: Polyporenic acid C induces caspase-8-mediated apoptosis in human lung cancer A549 cells.
Journal: Molecular carcinogenesis 20090601
Title: Age-dependent increase in desmosterol restores DRM formation and membrane-related functions in cholesterol-free DHCR24-/- mice.
Journal: Neurochemical research 20090601
Title: Sterol content analysis suggests altered eburicol 14alpha-demethylase (CYP51) activity in isolates of Mycosphaerella graminicola adapted to azole fungicides.
Journal: FEMS microbiology letters 20090601
Title: Cyclodextrin-modified capillary electrophoresis for achiral and chiral separation of ergostane and lanostane compounds extracted from the fruiting body of Antrodia camphorata.
Journal: Electrophoresis 20090601
Title: Lanosterol metabolic product(s) is involved in primordial folliculogenesis and establishment of primordial follicle pool in mouse fetal ovary.
Journal: Molecular reproduction and development 20090501
Title: Antiplasmodial and other constituents from four Indonesian Garcinia spp.
Journal: Phytochemistry 20090501
Title: Cytolethal distending toxin-induced cell cycle arrest of lymphocytes is dependent upon recognition and binding to cholesterol.
Journal: The Journal of biological chemistry 20090417
Title: The construction and characterization of self-sufficient lanosterol 14-demethylase fusion proteins consisting of yeast CYP51 and its reductase.
Journal: Biological & pharmaceutical bulletin 20090401
Title: Compound MMH01 possesses toxicity against human leukemia and pancreatic cancer cells.
Journal: Toxicology in vitro : an international journal published in association with BIBRA 20090401
Title: Performance analyses of a pH-shift and DOT-shift integrated fed-batch fermentation process for the production of ganoderic acid and Ganoderma polysaccharides by medicinal mushroom Ganoderma lucidum.
Journal: Bioresource technology 20090301
Title: Modified oxidosqualene cyclases in the formation of bioactive secondary metabolites: biosynthesis of the antitumor clavaric acid.
Journal: Fungal genetics and biology : FG & B 20090301
Title: Drug interaction potential of 2-((3,4-dichlorophenethyl)(propyl)amino)-1-(pyridin-3-yl)ethanol (LK-935), the novel nonstatin-type cholesterol-lowering agent.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20090201
Title: Trypanosoma cruzi CYP51 inhibitor derived from a Mycobacterium tuberculosis screen hit.
Journal: PLoS neglected tropical diseases 20090201
Title: Sterol 24-C-methyltransferase: an enzymatic target for the disruption of ergosterol biosynthesis and homeostasis in Cryptococcus neoformans.
Journal: Archives of biochemistry and biophysics 20090115
Title: The effect of plagiochin E alone and in combination with fluconazole on the ergosterol biosynthesis of Candida albicans.
Journal: Biological & pharmaceutical bulletin 20090101
Title: Characterization of sterol lipids in Kluyveromyces lactis strain M-16 accumulating a high amount of steryl glucoside.
Journal: Journal of oleo science 20090101
Title: Transcriptional profiling of the effects of 25-hydroxycholesterol on human hepatocyte metabolism and the antiviral state it conveys against the hepatitis C virus.
Journal: BMC chemical biology 20090101
Title: Revision of the absolute configuration at C(23) of lanostanoids and isolation of secondary metabolites from formosan soft coral Nephthea erecta.
Journal: Chemistry & biodiversity 20090101
Title: Sequential metabolism of 7-dehydrocholesterol to steroidal 5,7-dienes in adrenal glands and its biological implication in the skin.
Journal: PloS one 20090101
Title: Regulation of clock-controlled genes in mammals.
Journal: PloS one 20090101
Title: Influence of the cystic fibrosis transmembrane conductance regulator on expression of lipid metabolism-related genes in dendritic cells.
Journal: Respiratory research 20090101
Title: Growth inhibition and ultrastructural alterations induced by Delta24(25)-sterol methyltransferase inhibitors in Candida spp. isolates, including non-albicans organisms.
Journal: BMC microbiology 20090101
Title: Sterol metabolism in the oomycete Aphanomyces euteiches, a legume root pathogen.
Journal: The New phytologist 20090101
Title: LeishCyc: a biochemical pathways database for Leishmania major.
Journal: BMC systems biology 20090101
Title: Targeted suppression of heme oxygenase-1 by small interference RNAs inhibits the production of bilirubin in neonatal rat with hyperbilirubinemia.
Journal: BMC molecular biology 20090101
Title: Progressive obesity leads to altered ovarian gene expression in the Lethal Yellow mouse: a microarray study.
Journal: Journal of ovarian research 20090101
Title: Early development of Moniliophthora perniciosa basidiomata and developmentally regulated genes.
Journal: BMC microbiology 20090101
Title: Sterol Biosynthesis Pathway as Target for Anti-trypanosomatid Drugs.
Journal: Interdisciplinary perspectives on infectious diseases 20090101
Title: Rapid detection of ERG11 gene mutations in clinical Candida albicans isolates with reduced susceptibility to fluconazole by rolling circle amplification and DNA sequencing.
Journal: BMC microbiology 20090101
Title: Management of invasive aspergillosis in patients with COPD: rational use of voriconazole.
Journal: International journal of chronic obstructive pulmonary disease 20090101
Title: Gene array analysis of adrenal glands in broiler chickens following ACTH treatment.
Journal: BMC genomics 20090101
Title: Transcriptional profiling of rats subjected to gestational undernourishment: implications for the developmental variations in metabolic traits.
Journal: PloS one 20090101
Title: Fixed drug eruption resulting from fluconazole use: a case report.
Journal: Journal of medical case reports 20090101
Title: Transcriptome analysis of differentiating trypanosomes reveals the existence of multiple post-transcriptional regulons.
Journal: BMC genomics 20090101
Title: Investigating the effects of statins on cellular lipid metabolism using a yeast expression system.
Journal: PloS one 20090101
Title: Phylogenomics of sterol synthesis: insights into the origin, evolution, and diversity of a key eukaryotic feature.
Journal: Genome biology and evolution 20090101
Title: Simultaneous HPLC determination of butenafine hydrochloride and betamethasone in a cream formulation.
Journal: Indian journal of pharmaceutical sciences 20090101
Title: Economic considerations in the treatment of invasive aspergillosis: a review of voriconazole pharmacoeconomic studies.
Journal: ClinicoEconomics and outcomes research : CEOR 20090101
Title: Elevated cholesterol precursors other than cholestanol can also be a hallmark for CTX.
Journal: Journal of inherited metabolic disease 20081201
Title: Lanostane-type triterpenes from the mushroom Astraeus pteridis with antituberculosis activity.
Journal: Journal of natural products 20081201
Title: Two novel A-seco-rearranged lanostane triterpenoids from Abies sachalinensis.
Journal: Archives of pharmacal research 20081201
Title: Loss of gamma-secretase function impairs endocytosis of lipoprotein particles and membrane cholesterol homeostasis.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20081112
Title: Importance of Saccharomyces cerevisiae oxidosqualene-lanosterol cyclase tyrosine 707 residue for chair-boat bicyclic ring formation and deprotonation reactions.
Journal: Organic letters 20081106
Title: Antifungal activity of 25-azalanosterol against Candida species.
Journal: European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 20081101
Title: A sterol-regulatory element binding protein is required for cell polarity, hypoxia adaptation, azole drug resistance, and virulence in Aspergillus fumigatus.
Journal: PLoS pathogens 20081101
Title: Overexpression of human ABCG1 does not affect atherosclerosis in fat-fed ApoE-deficient mice.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20081001
Title: Gas chromatographic-mass spectrometric analyses of cholesterol and its precursors in rat plasma as tert-butyldimethylsilyl derivatives.
Journal: Clinica chimica acta; international journal of clinical chemistry 20081001
Title: Differential azole antifungal efficacies contrasted using a Saccharomyces cerevisiae strain humanized for sterol 14 alpha-demethylase at the homologous locus.
Journal: Antimicrobial agents and chemotherapy 20081001
Title: Disruption of the gene encoding 3beta-hydroxysterol Delta-reductase (Tm7sf2) in mice does not impair cholesterol biosynthesis.
Journal: The FEBS journal 20081001
Title: Cytotoxic and anti-oxidant activities of lanostane-type triterpenes isolated from Poria cocos.
Journal: Chemical & pharmaceutical bulletin 20081001
Title: Regulation of cholesterologenesis by the oxysterol receptor, LXRalpha.
Journal: The Journal of biological chemistry 20080926
Title: Interfacial behavior of cholesterol, ergosterol, and lanosterol in mixtures with DPPC and DMPC.
Journal: Biophysical journal 20080901
Title: Multiple effects of a novel compound from Burkholderia cepacia against Candida albicans.
Journal: FEMS microbiology letters 20080801
Title: Posaconazole in the management of refractory invasive fungal infections.
Journal: Therapeutics and clinical risk management 20080801
Title: Spheciosterol sulfates, PKCzeta inhibitors from a philippine sponge Spheciospongia sp.
Journal: Journal of natural products 20080725
Title: Expression of microsomal lanosterol 14alpha-demethylase (CYP51) in an engineered soluble monomeric form.
Journal: Biochemical and biophysical research communications 20080711
Title: Nonenzymic polycyclization of analogues of oxidosqualene with a preformed C-ring.
Journal: Organic & biomolecular chemistry 20080607
Title: Cholesterol, lanosterol, and ergosterol attenuate the membrane association of LL-37(W27F) and temporin L.
Journal: Biochimica et biophysica acta 20080601
Title: Lanostane-type triterpenoids from the roots of Kadsura coccinea.
Journal: Journal of natural products 20080601
Title: Silencing of mouse hepatic lanosterol 14-alpha demethylase down-regulated plasma low-density lipoprotein cholesterol levels by short-term treatment of siRNA.
Journal: Biological & pharmaceutical bulletin 20080601
Title: Anti-HIV-1 protease activity of lanostane triterpenes from the vietnamese mushroom Ganoderma colossum.
Journal: Journal of natural products 20080601
Title: Characteristics of biofilm formation by Candida tropicalis and antifungal resistance.
Journal: FEMS yeast research 20080501
Title: Ganoderic acids suppress growth and invasive behavior of breast cancer cells by modulating AP-1 and NF-kappaB signaling.
Journal: International journal of molecular medicine 20080501
Title: ATP-binding cassette transporters G1 and G4 mediate cholesterol and desmosterol efflux to HDL and regulate sterol accumulation in the brain.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20080401
Title: Kadsuracoccinic acids A-C, ring-A seco-lanostane triterpenes from Kadsura coccinea and their effects on embryonic cell division of Xenopus laevis.
Journal: Journal of natural products 20080401
Title: Novel lanostane and rearranged lanostane-type triterpenoids from Abies sachalinensis - II -.
Journal: Chemical & pharmaceutical bulletin 20080401
Title: Oxysterols: novel biologic roles for the 21st century.
Journal: Steroids 20080201
Title: Effectors of rapid homeostatic responses of endoplasmic reticulum cholesterol and 3-hydroxy-3-methylglutaryl-CoA reductase.
Journal: The Journal of biological chemistry 20080118
Title: Moderately elevated plant sterol levels are associated with reduced cardiovascular risk--the LASA study.
Journal: Atherosclerosis 20080101
Title: Novel cholesterol biosynthesis inhibitors targeting human lanosterol 14alpha-demethylase (CYP51).
Journal: Bioorganic & medicinal chemistry 20080101
Title: Metabolic model integration of the bibliome, genome, metabolome and reactome of Aspergillus niger.
Journal: Molecular systems biology 20080101
Title: Novel role for SLPI in MOG-induced EAE revealed by spinal cord expression analysis.
Journal: Journal of neuroinflammation 20080101
Title: [Chemical constituents of the spores of Ganoderma lucidum].
Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20080101
Title: Preservation of genes involved in sterol metabolism in cholesterol auxotrophs: facts and hypotheses.
Journal: PloS one 20080101
Title: Metabolic innovations towards the human lineage.
Journal: BMC evolutionary biology 20080101
Title: Altered bile acid metabolism in patients with constipation-predominant irritable bowel syndrome and functional constipation.
Journal: Scandinavian journal of gastroenterology 20080101
Title: Breast cancer proteomics reveals correlation between estrogen receptor status and differential phosphorylation of PGRMC1.
Journal: Breast cancer research : BCR 20080101
Title: Histone deacetylase inhibitors: a new mode for inhibition of cholesterol metabolism.
Journal: BMC genomics 20080101
Title: Expression and regulation of lanosterol 14alpha-demethylase in mouse embryo and uterus during the peri-implantation period.
Journal: Reproduction, fertility, and development 20080101
Title: Insulin-like growth factor-1 coordinately induces the expression of fatty acid and cholesterol biosynthetic genes in murine C2C12 myoblasts.
Journal: BMC genomics 20080101
Title: Dynamical modeling of the cholesterol regulatory pathway with Boolean networks.
Journal: BMC systems biology 20080101
Title: Inotodiol, a lanostane triterpenoid, from Inonotus obliquus inhibits cell proliferation through caspase-3-dependent apoptosis.
Journal: Anticancer research 20080101
Title: Monocytes of patients with familial hypercholesterolemia show alterations in cholesterol metabolism.
Journal: BMC medical genomics 20080101
Title: A novel three-stage light irradiation strategy in the submerged fermentation of medicinal mushroom Ganoderma lucidum for the efficient production of ganoderic acid and Ganoderma polysaccharides.
Journal: Biotechnology progress 20080101
Title: Antifungals: need to search for a new molecular target.
Journal: Indian journal of pharmaceutical sciences 20080101
Title: Hypolipidemia: a word of caution.
Journal: The Libyan journal of medicine 20080101
Title: Histone deacetylase 3 down-regulates cholesterol synthesis through repression of lanosterol synthase gene expression.
Journal: The Journal of biological chemistry 20071207
Title: cis-Acting elements within the Candida albicans ERG11 promoter mediate the azole response through transcription factor Upc2p.
Journal: Eukaryotic cell 20071201
Title: A squalene epoxidase is involved in biosynthesis of both the antitumor compound clavaric acid and sterols in the basidiomycete H. sublateritium.
Journal: Chemistry & biology 20071201
Title: Biosynthesis of phytosterol esters: identification of a sterol o-acyltransferase in Arabidopsis.
Journal: Plant physiology 20071101
Title: Synthesis and antifungal activities of novel 2-aminotetralin derivatives.
Journal: Journal of medicinal chemistry 20071101
Title: [Application of binding spectra in DMIs fungicide screening].
Journal: Sheng wu gong cheng xue bao = Chinese journal of biotechnology 20071101
Title: [Study on chemical constituents from rhizomes of Actaea asiatica].
Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20071101
Title: Progressive dysfunction of the cholesterol biosynthesis pathway in the R6/2 mouse model of Huntington's disease.
Journal: Neurobiology of disease 20071001
Title: Sterol biosynthesis by a prokaryote: first in vitro identification of the genes encoding squalene epoxidase and lanosterol synthase from Methylococcus capsulatus.
Journal: Bioscience, biotechnology, and biochemistry 20071001
Title: Hypoxia stimulates degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase through accumulation of lanosterol and hypoxia-inducible factor-mediated induction of insigs.
Journal: The Journal of biological chemistry 20070914
Title: The farnesoid X receptor FXRalpha/NR1H4 acquired ligand specificity for bile salts late in vertebrate evolution.
Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20070901
Title: Structure elucidation and complete NMR spectral assignments of three new lanostanoid triterpenes with unprecedented Delta(16, 17) double bond from Ganoderma lucidum.
Journal: Magnetic resonance in chemistry : MRC 20070901
Title: Atorvastatin in patients with primary biliary cirrhosis and incomplete biochemical response to ursodeoxycholic acid.
Journal: Hepatology (Baltimore, Md.) 20070901
Title: 4-Methyl sterols regulate fission yeast SREBP-Scap under low oxygen and cell stress.
Journal: The Journal of biological chemistry 20070817
Title: Conformational dynamics in the F/G segment of CYP51 from Mycobacterium tuberculosis monitored by FRET.
Journal: Archives of biochemistry and biophysics 20070815
Title: Lanosterol biosynthesis in the prokaryote Methylococcus capsulatus: insight into the evolution of sterol biosynthesis.
Journal: Molecular biology and evolution 20070801
Title: Role of posaconazole in the management of oropharyngeal and esophageal candidiasis.
Journal: Therapeutics and clinical risk management 20070801
Title: Design, synthesis, and antifungal activities of novel 1H-triazole derivatives based on the structure of the active site of fungal lanosterol 14 alpha-demethylase (CYP51).
Journal: Chemistry & biodiversity 20070701
Title: Sterol composition in field-grown and cultured mycelia of Inonotus obliquus.
Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20070701
Title: [Studies on the chemical constituents from herba anoectochili].
Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20070701
Title: Regulation of hepatic Insig-2 by the farnesoid X receptor.
Journal: Molecular endocrinology (Baltimore, Md.) 20070601
Title: Enhancement of IL-2 and IFN-gamma expression and NK cells activity involved in the anti-tumor effect of ganoderic acid Me in vivo.
Journal: International immunopharmacology 20070601
Title: Electrochemical reduction of sterol-14alpha-demethylase from Mycobacterium tuberculosis (CYP51b1).
Journal: Biochemistry. Biokhimiia 20070601
Title: Diterpenoids and triterpenoids from Euphorbia guyoniana.
Journal: Phytochemistry 20070501
Title: Hepatic cytochrome P450 reductase-null mice reveal a second microsomal reductase for squalene monooxygenase.
Journal: Archives of biochemistry and biophysics 20070501
Title: Electrochemical properties of cytochroms P450 using nanostructured electrodes: direct electron transfer and electro catalysis.
Journal: Journal of inorganic biochemistry 20070501
Title: Rapid birth-death evolution specific to xenobiotic cytochrome P450 genes in vertebrates.
Journal: PLoS genetics 20070501
Title: Inhibition of angiogenesis by the antifungal drug itraconazole.
Journal: ACS chemical biology 20070424
Title: Structure of mixed micelles formed in PEG-lipid/lipid dispersions.
Journal: Langmuir : the ACS journal of surfaces and colloids 20070410
Title: Separation and determination of diversiform phytosterols in food materials using supercritical carbon dioxide extraction and ultraperformance liquid chromatography-atmospheric pressure chemical ionization-mass spectrometry.
Journal: Analytica chimica acta 20070404
Title: Cholesterol starvation induces differentiation of human leukemia HL-60 cells.
Journal: Cancer research 20070401
Title: [Study on chemical constituents of Euphorbia hylonoma hand. -Mazz].
Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20070401
Title: Three-dimensional quantitative structure-activity relationship analysis of human CYP51 inhibitors.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20070301
Title: Differential effects of cholesterol, ergosterol and lanosterol on a dipalmitoyl phosphatidylcholine membrane: a molecular dynamics simulation study.
Journal: The journal of physical chemistry. B 20070222
Title: Syntheses of ring C oxysterols: inhibitors of sterol biosynthesis.
Journal: Lipids 20070201
Title: Structure determination of inonotsuoxides A and B and in vivo anti-tumor promoting activity of inotodiol from the sclerotia of Inonotus obliquus.
Journal: Bioorganic & medicinal chemistry 20070101
Title: Amaranth oil application for coronary heart disease and hypertension.
Journal: Lipids in health and disease 20070101
Title: Preparative isolation of cyclolanostane-type saponins from Astragalus membranaceus bge. var. mongholicus (Bge.) Hsiao by TLC-MS/MS guided high-speed counter-current chromatography.
Journal: Journal of separation science 20070101
Title: The Interleukin-6 inflammation pathway from cholesterol to aging--role of statins, bisphosphonates and plant polyphenols in aging and age-related diseases.
Journal: Immunity & ageing : I & A 20070101
Title: Synthesis of the oxysterol, 24(S), 25-epoxycholesterol, parallels cholesterol production and may protect against cellular accumulation of newly-synthesized cholesterol.
Journal: Lipids in health and disease 20070101
Title: The transcriptome analysis of early morphogenesis in Paracoccidioides brasiliensis mycelium reveals novel and induced genes potentially associated to the dimorphic process.
Journal: BMC microbiology 20070101
Title: Transcriptome of Pneumocystis carinii during fulminate infection: carbohydrate metabolism and the concept of a compatible parasite.
Journal: PloS one 20070101
Title: Genomic analysis of the secretion stress response in the enzyme-producing cell factory Aspergillus niger.
Journal: BMC genomics 20070101
Title: Gene expression profiles in testis of pigs with extreme high and low levels of androstenone.
Journal: BMC genomics 20070101
Title: Coordinate up-regulation of TMEM97 and cholesterol biosynthesis genes in normal ovarian surface epithelial cells treated with progesterone: implications for pathogenesis of ovarian cancer.
Journal: BMC cancer 20070101
Title: Photosensitivity in Smith-Lemli-Opitz syndrome: a flux balance analysis of altered metabolism.
Journal: Bioinformation 20070101
Title: Trametes versatillis, a fungus highly producing eburicoic acid.
Journal: Zeitschrift fur Naturforschung. C, Journal of biosciences 20070101
Title: Separation of free sterols by high temperature liquid chromatography.
Journal: Journal of chromatography. A 20061229
Title: Ganoderic acid T from Ganoderma lucidum mycelia induces mitochondria mediated apoptosis in lung cancer cells.
Journal: Life sciences 20061223
Title: Comparison of lanosterol-14 alpha-demethylase (CYP51) of human and Candida albicans for inhibition by different antifungal azoles.
Journal: Toxicology 20061110
Title: Comparative calorimetric and spectroscopic studies of the effects of lanosterol and cholesterol on the thermotropic phase behavior and organization of dipalmitoylphosphatidylcholine bilayer membranes.
Journal: Biophysical journal 20061101
Title: Cloning of chicken lanosterol 14alpha-demethylase (CYP51) cDNA: discovery of a testis-specific CYP51 transcript.
Journal: Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20061101
Title: Design, synthesis, and antifungal activities in vitro of novel tetrahydroisoquinoline compounds based on the structure of lanosterol 14alpha-demethylase (CYP51) of fungi.
Journal: Bioorganic & medicinal chemistry letters 20061015
Title: Domain-formation in DOPC/SM bilayers studied by pfg-NMR: effect of sterol structure.
Journal: Biophysical journal 20061001
Title: Steroid structural requirements for interaction of ostreolysin, a lipid-raft binding cytolysin, with lipid monolayers and bilayers.
Journal: Biochimica et biophysica acta 20061001
Title: Inhibition of oxidative stress-induced invasiveness of cancer cells by Ganoderma lucidum is mediated through the suppression of interleukin-8 secretion.
Journal: International journal of molecular medicine 20061001
Title: Lanosterol 14alpha-demethylase expression in the mouse ovary and its participation in cumulus-enclosed oocyte spontaneous meiotic maturation in vitro.
Journal: Theriogenology 20060915
Title: New ganoderic acids, bioactive triterpenoid metabolites from the mushroom Ganoderma lucidum.
Journal: Natural product research 20060901
Title: Cholesterol precursors stabilize ordinary and ceramide-rich ordered lipid domains (lipid rafts) to different degrees. Implications for the Bloch hypothesis and sterol biosynthesis disorders.
Journal: The Journal of biological chemistry 20060804
Title: Synthetic studies toward highly functionalized 5beta-lanosterol derivatives: a versatile approach utilizing anionic cycloaddition.
Journal: The Journal of organic chemistry 20060804
Title: Cloning and characterization of CYP51 from Mycobacterium avium.
Journal: American journal of respiratory cell and molecular biology 20060801
Title: Phytosterol biosynthesis pathway in Mortierella alpina.
Journal: Phytochemistry 20060801
Title: Lanostane triterpenoids from the Sri Lankan basidiomycete Ganoderma applanatum.
Journal: Journal of natural products 20060801
Title: Cholesterol synthesis rate in human hippocampus declines with aging.
Journal: Neuroscience letters 20060731
Title: Sterol dependent regulation of human TM7SF2 gene expression: role of the encoded 3beta-hydroxysterol Delta14-reductase in human cholesterol biosynthesis.
Journal: Biochimica et biophysica acta 20060701
Title: Classical QSAR study on chromene derivatives as lanosterol 14alpha- demethylase inhibitor: a non azole antifungal target.
Journal: Medicinal chemistry (Shariqah (United Arab Emirates)) 20060701
Title: Triadimefon causes branchial arch malformations in Xenopus laevis embryos.
Journal: Environmental science and pollution research international 20060701
Title: Puerarin decreases serum total cholesterol and enhances thoracic aorta endothelial nitric oxide synthase expression in diet-induced hypercholesterolemic rats.
Journal: Life sciences 20060620
Title: Influence of thermodynamic parameter in Lanosterol 14alpha-demethylase inhibitory activity as antifungal agents: a QSAR approach.
Journal: Biological & pharmaceutical bulletin 20060601
Title: Host-specific response to HCV infection in the chimeric SCID-beige/Alb-uPA mouse model: role of the innate antiviral immune response.
Journal: PLoS pathogens 20060601
Title: Voriconazole in the management of nosocomial invasive fungal infections.
Journal: Therapeutics and clinical risk management 20060601
Title: Site-saturated mutagenesis of histidine 234 of Saccharomyces cerevisiae oxidosqualene-lanosterol cyclase demonstrates dual functions in cyclization and rearrangement reactions.
Journal: Journal of the American Chemical Society 20060517
Title: Phase behavior of lipid monolayers containing DPPC and cholesterol analogs.
Journal: Biophysical journal 20060501
Title: Plant lanosterol synthase: divergence of the sterol and triterpene biosynthetic pathways in eukaryotes.
Journal: Plant & cell physiology 20060501
Title: Lanosterol synthase in dicotyledonous plants.
Journal: Plant & cell physiology 20060501
Title: [Studies on constituents from roots of Euphorbia hylonoma].
Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20060501
Title: Meiosis activating sterol (MAS) regulate FSH-induced meiotic resumption of cumulus cell-enclosed porcine oocytes via PKC pathway.
Journal: Molecular and cellular endocrinology 20060425
Title: Follicular sterol composition in gonadotrophin stimulated women with polycystic ovarian syndrome.
Journal: Molecular and cellular endocrinology 20060425
Title: Cimicifuga species identification by high performance liquid chromatography-photodiode array/mass spectrometric/evaporative light scattering detection for quality control of black cohosh products.
Journal: Journal of chromatography. A 20060421
Title: Structure-based optimization of azole antifungal agents by CoMFA, CoMSIA, and molecular docking.
Journal: Journal of medicinal chemistry 20060420
Title: Tryptophan 232 within oxidosqualene-lanosterol cyclase from Saccharomyces cerevisiae influences rearrangement and deprotonation but not cyclization reactions.
Journal: Organic letters 20060330
Title: Modulation of cholesterol metabolism by the green tea polyphenol (-)-epigallocatechin gallate in cultured human liver (HepG2) cells.
Journal: Journal of agricultural and food chemistry 20060308
Title: Universal behavior of membranes with sterols.
Journal: Biophysical journal 20060301
Title: Lanosterol biosynthesis in plants.
Journal: Archives of biochemistry and biophysics 20060301
Title: cDNA cloning, genomic structure and expression analysis of the bovine lanosterol 14alpha-demethylase (CYP51) in gonads.
Journal: Biological & pharmaceutical bulletin 20060301
Title: Mechanistic insights into triterpene synthesis from quantum mechanical calculations. Detection of systematic errors in B3LYP cyclization energies.
Journal: Organic & biomolecular chemistry 20060207
Title: Effect of geraniol on fatty-acid and mevalonate metabolism in the human hepatoma cell line Hep G2.
Journal: Biochemistry and cell biology = Biochimie et biologie cellulaire 20060201
Title: Cytotoxicity of cycloartane triterpenoids from aerial part of Cimicifuga foetida.
Journal: Fitoterapia 20060101
Title: Investigation of de novo cholesterol synthetic capacity in the gonads of goldfish (Carassius auratus) exposed to the phytosterol beta-sitosterol.
Journal: Reproductive biology and endocrinology : RB&E 20060101
Title: [Nanoelectrochemistry of cytochrome P450s: direct electron transfer and electrocatalysis].
Journal: Biomeditsinskaia khimiia 20060101
Title: Bilayer thickness and thermal response of dimyristoylphosphatidylcholine unilamellar vesicles containing cholesterol, ergosterol and lanosterol: a small-angle neutron scattering study.
Journal: Biochimica et biophysica acta 20051230
Title: Cholesterogenic lanosterol 14alpha-demethylase (CYP51) is an immediate early response gene.
Journal: Endocrinology 20051201
Title: A new cytotoxic lanostane triterpenoid from the basidiomycete Hebeloma versipelle.
Journal: The Journal of antibiotics 20051201
Title: Sterol profiling of amniotic fluid: a routine method for the detection of distal cholesterol synthesis deficit.
Journal: Prenatal diagnosis 20051101
Title: Enzyme redesign: two mutations cooperate to convert cycloartenol synthase into an accurate lanosterol synthase.
Journal: Journal of the American Chemical Society 20051019
Title: A molecular mechanics force field for biologically important sterols.
Journal: Journal of computational chemistry 20051001
Title: Diffusion of cholesterol and its precursors in lipid membranes studied by 1H pulsed field gradient magic angle spinning NMR.
Journal: Biophysical journal 20051001
Title: Lipid signaling in plants. Cloning and expression analysis of the obtusifoliol 14alpha-demethylase from Solanum chacoense Bitt., a pollination- and fertilization-induced gene with both obtusifoliol and lanosterol demethylase activity.
Journal: Plant physiology 20051001
Title: Reductions in cholesterol and synaptic markers in association cortex in mood disorders.
Journal: Bipolar disorders 20051001
Title: Sterol structure determines miscibility versus melting transitions in lipid vesicles.
Journal: Biophysical journal 20050901
Title: The protein farnesyltransferase inhibitor Tipifarnib as a new lead for the development of drugs against Chagas disease.
Journal: Journal of medicinal chemistry 20050825
Title: Fluconazole upregulates sconC expression and inhibits sulphur metabolism in Microsporum canis.
Journal: Fungal genetics and biology : FG & B 20050801
Title: A prospective, randomized, double-blind, placebo-controlled study of the platelet and global hemostatic effects of Ganoderma lucidum (Ling-Zhi) in healthy volunteers.
Journal: Anesthesia and analgesia 20050801
Title: In vitro antifungal activity of ZJ-522, a new triazole restructured from fluconazole and butenafine, against clinically important fungi in comparison with fluconazole and butenafine.
Journal: Biological & pharmaceutical bulletin 20050801
Title: Friedolanostanes and lanostanes from the leaves of Garcinia hombroniana.
Journal: Journal of natural products 20050801
Title: Norlanostane triterpenoidal saponins from the marine sponge melophlussarassinorum.
Journal: Journal of natural products 20050801
Title: [Studies on chemical constitutes of green alga Chaetomorpha basiretorsa and their bioactivity].
Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20050801
Title: Flux of sterol intermediates in a yeast strain deleted of the lanosterol C-14 demethylase Erg11p.
Journal: Biochimica et biophysica acta 20050715
Title: Cytochrome P450 17alpha hydroxylase/17,20 lyase (CYP17) function in cholesterol biosynthesis: identification of squalene monooxygenase (epoxidase) activity associated with CYP17 in Leydig cells.
Journal: Molecular endocrinology (Baltimore, Md.) 20050701
Title: Ganoderic acid Sz, a new lanostanoid from the mushroom Ganoderma lucidum.
Journal: Natural product research 20050701
Title: Lord of the rings--the mechanism for oxidosqualene:lanosterol cyclase becomes crystal clear.
Journal: Trends in pharmacological sciences 20050701
Title: Synthetic lanostane-type triterpenoids as inhibitors of DNA topoisomerase II.
Journal: Bioorganic & medicinal chemistry letters 20050615
Title: Ganoderic acid X, a lanostanoid triterpene, inhibits topoisomerases and induces apoptosis of cancer cells.
Journal: Life sciences 20050603
Title: N-Phenethylhexadecanamide from the edible mushroom Laetiporus sulphureus.
Journal: Natural product research 20050601
Title: Cytotoxic constituents of the fruit body of Daedalea dickisii.
Journal: Journal of natural products 20050601
Title: Sterol stringency of proliferation and cell cycle progression in human cells.
Journal: Biochimica et biophysica acta 20050515
Title: Differences in the modulation of collective membrane motions by ergosterol, lanosterol, and cholesterol: a dynamic light scattering study.
Journal: Biophysical journal 20050501
Title: Pre-cholesterol precursors in gametogenesis.
Journal: Molecular and cellular endocrinology 20050429
Title: The imidazoline-like drug S23515 affects lipid metabolism in hepatocyte by inhibiting the oxidosqualene: lanosterol cyclase activity.
Journal: Biochemical pharmacology 20050401
Title: Determination of sterols in biological samples by SPME with on-fiber derivatization and GC/FID.
Journal: Analytical and bioanalytical chemistry 20050401
Title: Oxygenated lanostane-type triterpenoids from the fungus ganodermalucidum.
Journal: Journal of natural products 20050401
Title: How low can you go?
Journal: Science of aging knowledge environment : SAGE KE 20050316
Title: Desmosterol may replace cholesterol in lipid membranes.
Journal: Biophysical journal 20050301
Title: Dual-action hypoglycemic and hypocholesterolemic agents that inhibit glycogen phosphorylase and lanosterol demethylase.
Journal: Journal of lipid research 20050301
Title: Isotopomer spectral analysis of intermediates of cholesterol synthesis in patients with cerebrotendinous xanthomatosis.
Journal: Metabolism: clinical and experimental 20050301
Title: Insig-mediated degradation of HMG CoA reductase stimulated by lanosterol, an intermediate in the synthesis of cholesterol.
Journal: Cell metabolism 20050301
Title: Cancer preventive agents. Part 1: chemopreventive potential of cimigenol, cimigenol-3,15-dione, and related compounds.
Journal: Bioorganic & medicinal chemistry 20050215
Title: Antiproliferative synergism of azasterols and antifolates against Toxoplasma gondii.
Journal: International journal of antimicrobial agents 20050201
Title: The combination effects of phenolic compounds and fluconazole on the formation of ergosterol in Candida albicans determined by high-performance liquid chromatography/tandem mass spectrometry.
Journal: Analytical biochemistry 20050101
Title: Multidrug resistance in yeast Candida.
Journal: International review of cytology 20050101
Title: Aspergillus oryzae produces compounds inhibiting cholesterol biosynthesis downstream of dihydrolanosterol.
Journal: FEMS microbiology letters 20050101
Title: Lanostane triterpenoids and triterpene glycosides from the fruit body of Fomitopsis pinicola and their inhibitory activity against COX-1 and COX-2.
Journal: Journal of natural products 20050101
Title: MT FdR: a ferredoxin reductase from M. tuberculosis that couples to MT CYP51.
Journal: Biochimica et biophysica acta 20050101
Title: Exploring hepatic hormone actions using a compilation of gene expression profiles.
Journal: BMC physiology 20050101
Title: Genome-wide structural and evolutionary analysis of the P450 monooxygenase genes (P450ome) in the white rot fungus Phanerochaete chrysosporium: evidence for gene duplications and extensive gene clustering.
Journal: BMC genomics 20050101
Title: Vesicle fluctuation analysis of the effects of sterols on membrane bending rigidity.
Journal: European biophysics journal : EBJ 20041201
Title: Meiosis-activating sterol synthesis in rat preovulatory follicle: is it involved in resumption of meiosis?
Journal: Biology of reproduction 20041201
Title: Lead nitrate-induced development of hypercholesterolemia in rats: sterol-independent gene regulation of hepatic enzymes responsible for cholesterol homeostasis.
Journal: Toxicology letters 20041201
Title: Lanostanoid triterpenes from Laetiporus sulphureus and apoptosis induction on HL-60 human myeloid leukemia cells.
Journal: Journal of natural products 20041201
Title: Bioactive friedolanostanes and 11(10-->8)-abeolanostanes from the bark of Garcinia speciosa.
Journal: Journal of natural products 20041201
Title: 27-norlanostane glycosides from the bulbs of Muscari paradoxum.
Journal: Journal of natural products 20041201
Title: Studies on the expression levels of sterol-metabolizing enzymes in the obese model SHR/NDmcr-cp rats.
Journal: Clinical and experimental pharmacology & physiology 20041201
Title: Biochemical characterization of terbinafine-resistant Trichophyton rubrum isolates.
Journal: Medical mycology 20041201
Title: Molecular mechanisms of vitamin E transport.
Journal: Annals of the New York Academy of Sciences 20041201
Title: Cloning and characterization of the lanosterol 14alpha-demethylase (ERG11) gene in Cryptococcus neoformans.
Journal: Biochemical and biophysical research communications 20041112
Title: Insight into steroid scaffold formation from the structure of human oxidosqualene cyclase.
Journal: Nature 20041104
Title: Agrobacterium tumefaciens-mediated transformation of the antitumor clavaric acid-producing basidiomycete Hypholoma sublateritium.
Journal: Current genetics 20041101
Title: New lanostane-type triterpenes from Fomes officinalis.
Journal: Chemical & pharmaceutical bulletin 20041101
Title: Anti-inflammatory and anti-hyaluronate lyase activities of lanostanoids from Piptoporus betulinus.
Journal: The Journal of antibiotics 20041101
Title: What's so special about cholesterol?
Journal: Lipids 20041101
Title: Cholesterol is essential for mitosis progression and its deficiency induces polyploid cell formation.
Journal: Experimental cell research 20041015
Title: Geranylgeraniol regulates negatively caspase-1 autoprocessing: implication in the Th1 response against Mycobacterium tuberculosis.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20041015
Title: Oxysteroids: a new class of steroids with autocrine and paracrine functions.
Journal: Trends in endocrinology and metabolism: TEM 20041001
Title: Abnormal steroidogenesis in three patients with Antley-Bixler syndrome: apparent decreased activity of 17alpha-hydroxylase, 17,20-lyase and 21-hydroxylase.
Journal: Pediatrics international : official journal of the Japan Pediatric Society 20041001
Title: Low concentrations of the non-ionic detergent Nonidet P-40 interfere with sterol biogenesis and viability of the yeast Saccharomyces cerevisiae.
Journal: FEMS microbiology letters 20040901
Title: A low-toxicity method for the separation of lanosterol and dihydrolanosterol from commercial mixtures.
Journal: Steroids 20040901
Title: CYP51 from Trypanosoma brucei is obtusifoliol-specific.
Journal: Biochemistry 20040824
Title: Undetectable maternal serum uE3 and postnatal abnormal sterol and steroid metabolism in Antley-Bixler syndrome.
Journal: American journal of medical genetics. Part A 20040815
Title: Genome-wide expression profiling reveals genes associated with amphotericin B and fluconazole resistance in experimentally induced antifungal resistant isolates of Candida albicans.
Journal: The Journal of antimicrobial chemotherapy 20040801
Title: Homology modeling of lanosterol 14alpha-demethylase of Candida albicans and Aspergillus fumigatus and insights into the enzyme-substrate Interactions.
Journal: Journal of biomolecular structure & dynamics 20040801
Title: Compound heterozygous mutations of cytochrome P450 oxidoreductase gene (POR) in two patients with Antley-Bixler syndrome.
Journal: American journal of medical genetics. Part A 20040801
Title: Quantitation of lanosterol and its major metabolite FF-MAS in an inhibition assay of CYP51 by azoles with atmospheric pressure photoionization based LC-MS/MS.
Journal: Journal of the American Society for Mass Spectrometry 20040801
Title: Sterol metabolism in the opportunistic pathogen Pneumocystis: advances and new insights.
Journal: Lipids 20040801
Title: New lanostane-type triterpenoids from Ganoderma applanatum.
Journal: Journal of natural products 20040701
Title: New aspects on lanosterol 14alpha-demethylase and cytochrome P450 evolution: lanosterol/cycloartenol diversification and lateral transfer.
Journal: Journal of molecular evolution 20040701
Title: Selective anti-Toxoplasma gondii activities of azasterols.
Journal: International journal of antimicrobial agents 20040601
Title: Phytoestrogen cimicifugoside-mediated inhibition of catecholamine secretion by blocking nicotinic acetylcholine receptor in bovine adrenal chromaffin cells.
Journal: The Journal of pharmacology and experimental therapeutics 20040501
Title: The role of cholesterol in the activity of pneumolysin, a bacterial protein toxin.
Journal: Biophysical journal 20040501
Title: Ananosic acids B and C, two new 18(13-->12)-abeo-lanostane triterpenoids from Kadsura ananosma.
Journal: Journal of natural products 20040501
Title: Eucosterol-type nortriterpenoids from Merwilla natalensis.
Journal: Journal of natural products 20040501
Title: Roles of gonadotropins and meiosis-activating sterols in meiotic resumption of cultured follicle-enclosed mouse oocytes.
Journal: Molecular and cellular endocrinology 20040415
Title: Efficient routes to epimerically-pure side-chain derivatives of lanosterol.
Journal: Steroids 20040401
Title: Enzymatic cyclization of 22,23-dihydro-2,3-oxidosqualene into euph-7-en-3beta-ol and bacchar-12-en-3beta-ol by recombinant beta-amyrin synthase.
Journal: Journal of the American Chemical Society 20040324
Title: The monotopic membrane protein human oxidosqualene cyclase is active as monomer.
Journal: Biochemical and biophysical research communications 20040305
Title: A functional cytochrome P450 lanosterol 14 alpha-demethylase CYP51 enzyme in the acrosome: transport through the Golgi and synthesis of meiosis-activating sterols.
Journal: Endocrinology 20040301
Title: Two new cyclolanostanol glycosides from the aerial parts of Cimicifuga foetida.
Journal: Journal of Asian natural products research 20040301
Title: Characterization of a human Sec14-like protein cDNA SEC14L3 highly homologous to human SPF/TAP.
Journal: Molecular biology reports 20040301
Title: Impact of 10 dietary sterols on growth and reproduction of Daphnia galeata.
Journal: Journal of chemical ecology 20040301
Title: CYP51--the omnipotent P450.
Journal: Molecular and cellular endocrinology 20040227
Title: Lanosterol and cholesterol-induced variations in bilayer elasticity probed by 2H NMR relaxation.
Journal: Langmuir : the ACS journal of surfaces and colloids 20040217
Title: Cholesterol-lowering properties of Ganoderma lucidum in vitro, ex vivo, and in hamsters and minipigs.
Journal: Lipids in health and disease 20040101
Title: Modeling lipid-sterol bilayers: applications to structural evolution, lateral diffusion, and rafts.
Journal: Methods in enzymology 20040101
Title: Fungal biofilms and drug resistance.
Journal: Emerging infectious diseases 20040101
Title: Cloning and analysis of Trypanosoma cruzi lanosterol 14alpha-demethylase.
Journal: Molecular and biochemical parasitology 20031201
Title: Novel sterols synthesized via the CYP27A1 metabolic pathway.
Journal: Archives of biochemistry and biophysics 20031201
Title: Lanosterol and tetranorlanosterol glycosides from the bulbs of Muscari paradoxum.
Journal: Phytochemistry 20031201
Title: Changes in cholesterol and its precursors during the first days after major trauma.
Journal: Wiener klinische Wochenschrift 20031128
Title: Combined overexpression of genes of the ergosterol biosynthetic pathway leads to accumulation of sterols in Saccharomyces cerevisiae.
Journal: FEMS yeast research 20031001
Title: Localization of mammalian NAD(P)H steroid dehydrogenase-like protein on lipid droplets.
Journal: The Journal of biological chemistry 20030919
Title: Conservation in the CYP51 family. Role of the B' helix/BC loop and helices F and G in enzymatic function.
Journal: Biochemistry 20030805
Title: Characterization of a lanosterol 14 alpha-demethylase from Pneumocystis carinii.
Journal: American journal of respiratory cell and molecular biology 20030801
Title: Anti-inflammatory lanostane-type triterpene acids from Piptoporus betulinus.
Journal: Journal of natural products 20030801
Title: In yeast sterol biosynthesis the 3-keto reductase protein (Erg27p) is required for oxidosqualene cyclase (Erg7p) activity.
Journal: Biochimica et biophysica acta 20030704
Title: Revision and confirmation of the regiochemistry of isoxazoles derived from methyl oleanonate and lanost-8-en-3-one. Synthesis of a new lanostane triterpenoid with a cyano-enone functionality in ring A.
Journal: The Journal of organic chemistry 20030613
Title: Lanosterol metabolism and sterol regulatory element binding protein (SREBP) expression in male germ cell maturation.
Journal: The Journal of steroid biochemistry and molecular biology 20030601
Title: Phylogeny of choanozoa, apusozoa, and other protozoa and early eukaryote megaevolution.
Journal: Journal of molecular evolution 20030501
Title: Mechanistic insights into oxidosqualene cyclizations through homology modeling.
Journal: Journal of computational chemistry 20030430
Title: Production of progesterone from de novo-synthesized cholesterol in cumulus cells and its physiological role during meiotic resumption of porcine oocytes.
Journal: Biology of reproduction 20030401
Title: Saccharomyces cerevisiae Dap1p, a novel DNA damage response protein related to the mammalian membrane-associated progesterone receptor.
Journal: Eukaryotic cell 20030401
Title: Antitumor agents 220. Antitumor-promoting effects of cimigenol and related compounds on Epstein-Barr virus activation and two-stage mouse skin carcinogenesis.
Journal: Bioorganic & medicinal chemistry 20030320
Title: Human serum paraoxonase 1 decreases macrophage cholesterol biosynthesis: possible role for its phospholipase-A2-like activity and lysophosphatidylcholine formation.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20030301
Title: Drug induced proteome changes in Candida albicans: comparison of the effect of beta(1,3) glucan synthase inhibitors and two triazoles, fluconazole and itraconazole.
Journal: Proteomics 20030301
Title: [Studies on the new triterpenoid saponin of the aerial part of Cimicifuga foetida].
Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20030301
Title: Structure-based de novo design, synthesis, and biological evaluation of non-azole inhibitors specific for lanosterol 14alpha-demethylase of fungi.
Journal: Journal of medicinal chemistry 20030213
Title: Conservation and cloning of CYP51: a sterol 14 alpha-demethylase from Mycobacterium smegmatis.
Journal: Biochemical and biophysical research communications 20030207
Title: Identification of farnesoid X receptor beta as a novel mammalian nuclear receptor sensing lanosterol.
Journal: Molecular and cellular biology 20030201
Title: Triterpenoids from the orchids Agrostophyllum brevipes and Agrostophyllum callosum.
Journal: Phytochemistry 20030201
Title: [Serum markers in relation to cognitive functioning in an aging population: results of the Maastricht Aging Study (MAAS)].
Journal: Tijdschrift voor gerontologie en geriatrie 20030201
Title: [Studies on new trierpenoid constituents from the Rhizoma of Cimicifuga foetida].
Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20030201
Title: Formation of the C ring in the lanosterol biosynthesis from squalene.
Journal: Organic letters 20030123
Title: Many facets of mammalian lanosterol 14alpha-demethylase from the evolutionarily conserved cytochrome P450 family CYP51.
Journal: Archives of biochemistry and biophysics 20030101
Title: Serum cholesterol, precursors and metabolites and cognitive performance in an aging population.
Journal: Neurobiology of aging 20030101
Title: Supernatant protein factor and tocopherol-associated protein: an unexpected link between cholesterol synthesis and vitamin E (review).
Journal: The Journal of nutritional biochemistry 20030101
Title: Protein prenyltransferases.
Journal: Genome biology 20030101
Title: Two new 24-isopropenyl-lanostanoids from Tillandsia brachycaulos.
Journal: Zeitschrift fur Naturforschung. C, Journal of biosciences 20030101
Title: Scale-up of a liquid static culture process for hyperproduction of ganoderic acid by the medicinal mushroom Ganoderma lucidum.
Journal: Biotechnology progress 20030101
Title: Identification of two proteins induced by exposure of the pathogenic fungus Candida glabrata to fluconazole.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20021225
Title: Creating new supramolecular materials by architecture of three-dimensional nanocrystal fiber networks.
Journal: Journal of the American Chemical Society 20021218
Title: Desmosterolosis presenting with multiple congenital anomalies and profound developmental delay.
Journal: American journal of medical genetics 20021215
Title: Directed evolution experiments reveal mutations at cycloartenol synthase residue His477 that dramatically alter catalysis.
Journal: Organic letters 20021212
Title: A novel sterol 14alpha-demethylase/ferredoxin fusion protein (MCCYP51FX) from Methylococcus capsulatus represents a new class of the cytochrome P450 superfamily.
Journal: The Journal of biological chemistry 20021206
Title: Nuclear receptor agonists stimulate release of arachidonic acid from rat liver cells.
Journal: Prostaglandins, leukotrienes, and essential fatty acids 20021201
Title: Sterol biosynthesis in Pneumocystis: unique steps that define unique targets.
Journal: Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 20021201
Title: Novel hydroquinone as a matrix metallo-proteinase inhibitor from the mushroom, Piptoporus betulinus.
Journal: Bioscience, biotechnology, and biochemistry 20021201
Title: The role of cytochrome P450 in the regulation of cholesterol biosynthesis.
Journal: Lipids 20021201
Title: Evidence for multiple sterol methyl transferase pathways in Pneumocystis carinii.
Journal: Lipids 20021201
Title: Progesterone and 17 alpha-OH-progesterone in concentrations similar to that of preovulatory follicular fluid is without effect on resumption of meiosis in mouse cumulus enclosed oocytes cultured in the presence of hypoxanthine.
Journal: Steroids 20021101
Title: Triterpenoid constituents isolated from the bark of Abies sachalinensis.
Journal: Journal of natural products 20021101
Title: Anisotropic motion and molecular dynamics of cholesterol, lanosterol, and ergosterol in lecithin bilayers studied by quasi-elastic neutron scattering.
Journal: Biochemistry 20021029
Title: Complete characterisation of lanolin steryl esters by sub-ambient pressure gas chromatography-mass spectrometry in the electron impact and chemical ionisation modes.
Journal: Journal of chromatography. A 20020913
Title: Concomitant C-ring Expansion and D-ring formation in lanosterol biosynthesis from squalene without violation of Markovnikov's rule.
Journal: Journal of the American Chemical Society 20020904
Title: A cAMP-responsive element binding site is essential for sterol regulation of the human lanosterol 14alpha-demethylase gene (CYP51).
Journal: Molecular endocrinology (Baltimore, Md.) 20020801
Title: Conversion of a plant oxidosqualene-cycloartenol synthase to an oxidosqualene-lanosterol cyclase by random mutagenesis.
Journal: Biochemistry 20020702
Title: Cholesterol metabolism in normal and heterozygous familial hypercholesterolemic newborns.
Journal: The Journal of laboratory and clinical medicine 20020701
Title: Profile of cholesterol-related sterols in aged amyloid precursor protein transgenic mouse brain.
Journal: Journal of lipid research 20020701
Title: Comprehensive and definitive structural identities of Pneumocystis carinii sterols.
Journal: Journal of lipid research 20020701
Title: Altered gene expression of hepatic lanosterol 14alpha-demethylase (CYP51) in lead nitrate-treated rats.
Journal: Archives of toxicology 20020701
Title: Abnormal sterol metabolism in a patient with Antley-Bixler syndrome and ambiguous genitalia.
Journal: American journal of medical genetics 20020615
Title: Sterol 14alpha-demethylase activity in Streptomyces coelicolor A3(2) is associated with an unusual member of the CYP51 gene family.
Journal: The Biochemical journal 20020601
Title: The Salmonella-containing vacuole is a major site of intracellular cholesterol accumulation and recruits the GPI-anchored protein CD55.
Journal: Cellular microbiology 20020601
Title: Polyene substrates with unusual methylation patterns to probe the active sites of three catalytic antibodies.
Journal: Bioorganic & medicinal chemistry 20020501
Title: The Pneumocystis carinii drug target S-adenosyl-L-methionine:sterol C-24 methyl transferase has a unique substrate preference.
Journal: Molecular microbiology 20020501
Title: Membrane-bound enzymes of cholesterol synthesis from lanosterol.
Journal: Biochemical and biophysical research communications 20020419
Title: My years with Konrad, a memoir.
Journal: Biochemical and biophysical research communications 20020419
Title: Directed evolution to generate cycloartenol synthase mutants that produce lanosterol.
Journal: Organic letters 20020418
Title: Inhibition of tumor-promoting effects by poricoic acids G and H and other lanostane-type triterpenes and cytotoxic activity of poricoic acids A and G from Poria cocos.
Journal: Journal of natural products 20020401
Title: New lanostanoids, elfvingic acids A-H, from the fruit body of Elfvingia applanata.
Journal: Journal of natural products 20020401
Title: Modeling of binding modes and inhibition mechanism of some natural ligands of farnesyl transferase using molecular docking.
Journal: Journal of medicinal chemistry 20020328
Title: Elution behavior of unsaponifiable lipids with various capillary electrochromatographic stationary phases.
Journal: Journal of chromatography. A 20020308
Title: From lanosterol to cholesterol: structural evolution and differential effects on lipid bilayers.
Journal: Biophysical journal 20020301
Title: Differential effects of ergosterol and cholesterol on Cdk1 activation and SRE-driven transcription.
Journal: European journal of biochemistry 20020301
Title: New lanostanoids from the fungus Ganoderma concinna.
Journal: Journal of natural products 20020301
Title: Mechanism of azole antifungal activity as determined by liquid chromatographic/mass spectrometric monitoring of ergosterol biosynthesis.
Journal: Journal of mass spectrometry : JMS 20020301
Title: Lanosterol 14alpha-demethylase and MAS sterols in mammalian gametogenesis.
Journal: Molecular and cellular endocrinology 20020222
Title: Role of meiosis activating sterols, MAS, in induced oocyte maturation.
Journal: Molecular and cellular endocrinology 20020222
Title: Molecular basis of resistance to azole antifungals.
Journal: Trends in molecular medicine 20020201
Title: Yeast oxidosqualene cyclase (Erg7p) is a major component of lipid particles.
Journal: The Journal of biological chemistry 20020125
Title: Cloning and expression of sterol Delta 14-reductase from bovine liver.
Journal: European journal of biochemistry 20020101
Title: New lanostanoids from the mushroom Ganoderma lucidum.
Journal: Journal of natural products 20020101
Title: Lanostanoids of Amentotaxus formosana.
Journal: Journal of natural products 20020101
Title: Two-stage culture process for improved production of ganoderic acid by liquid fermentation of higher fungus Ganoderma lucidum.
Journal: Biotechnology progress 20020101
Title: Is Pneumocystis a plant?
Journal: The Journal of eukaryotic microbiology 20020101
Title: Chemopreventive effect of farnesol and lanosterol on colon carcinogenesis.
Journal: Cancer detection and prevention 20020101
Title: Substrate recognition sites in 14alpha-sterol demethylase from comparative analysis of amino acid sequences and X-ray structure of Mycobacterium tuberculosis CYP51.
Journal: Journal of inorganic biochemistry 20011215
Title: Gonadotropin-induced accumulation of 4,4-dimethylsterols in mouse ovaries and its temporal relation to meiosis.
Journal: Biology of reproduction 20011201
Title: Anticomplement activity of terpenoids from the spores of Ganoderma lucidum.
Journal: Planta medica 20011201
Title: Regulation of hepatic lanosterol 14 alpha-demethylase gene expression by dietary cholesterol and cholesterol-lowering agents.
Journal: Archives of biochemistry and biophysics 20011115
Title: Steryl and stanyl esters of fatty acids by solvent-free esterification and transesterification in vacuo using lipases from Rhizomucor miehei, Candida antarctica, and Carica papaya.
Journal: Journal of agricultural and food chemistry 20011101
Title: Blocking protein geranylgeranylation is essential for lovastatin-induced apoptosis of human acute myeloid leukemia cells.
Journal: Leukemia 20010901
Title: New pentanorlanostane derivatives, cladosporide B-D, as characteristic antifungal agents against Aspergillus fumigatus, isolated from Cladosporium sp.
Journal: The Journal of antibiotics 20010901
Title: Identification of a novel mutation in 3beta-hydroxysteroid-Delta8-Delta7-isomerase in a case of Conradi-Hünermann-Happle syndrome.
Journal: Experimental dermatology 20010801
Title: [A new triterpene from the fruiting bodies of Ganoderma lucidum].
Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20010801
Title: Obtusifoliol 14alpha-demethylase (CYP51) antisense Arabidopsis shows slow growth and long life.
Journal: Biochemical and biophysical research communications 20010706
Title: The interactions of amphotericin B with various sterols in relation to its possible use in anticancer therapy.
Journal: Biophysical chemistry 20010702
Title: Neutral sterols of rat epididymis. High concentrations of dehydrocholesterols in rat caput epididymidis.
Journal: Journal of lipid research 20010701
Title: Content of meiosis activating sterols in equine follicular fluids: correlation to follicular size and dominance.
Journal: Theriogenology 20010701
Title: Trypanosome and animal lanosterol synthases use different catalytic motifs.
Journal: Organic letters 20010614
Title: Mammalian exocrine secretions XVI. Constitutents of secretion of supplementary sacculi of dwarf hamster, Phodopus sungorus sungorus.
Journal: Journal of chemical ecology 20010601
Title: Cholesterol biosynthesis from lanosterol. A concerted role for Sp1 and NF-Y-binding sites for sterol-mediated regulation of rat 7-dehydrocholesterol reductase gene expression.
Journal: The Journal of biological chemistry 20010525
Title: Molecular dynamics simulation of the structure of dimyristoylphosphatidylcholine bilayers with cholesterol, ergosterol, and lanosterol.
Journal: Biophysical journal 20010401
Title: Anaerobiosis induces complex changes in sterol esterification pattern in the yeast Saccharomyces cerevisiae.
Journal: FEMS microbiology letters 20010401
Title: Ergosterol biosynthesis in novel melanized fungi from hypersaline environments.
Journal: Journal of lipid research 20010301
Title: [Studies on quality specification standards for Saposhnicovia divaricata (Turcz.) Schischk].
Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20010301
Title: LDL downregulates CYP51 in porcine vascular endothelial cells and in the arterial wall through a sterol regulatory element binding protein-2-dependent mechanism.
Journal: Circulation research 20010216
Title: Cholesterol biosynthesis from lanosterol: molecular cloning, chromosomal localization, functional expression and liver-specific gene regulation of rat sterol delta8-isomerase, a cholesterogenic enzyme with multiple functions.
Journal: The Biochemical journal 20010201
Title: Meiosis-activating sterol and the maturation of isolated mouse oocytes.
Journal: Biology of reproduction 20010101
Title: Role of meiosis-activating sterols in rat oocyte maturation: effects of specific inhibitors and changes in the expression of lanosterol 14alpha-demethylase during the preovulatory period.
Journal: Biology of reproduction 20010101
Title: Quantification of plasma membrane ergosterol of Saccharomyces cerevisiae by direct-injection atmospheric pressure chemical ionization/tandem mass spectrometry.
Journal: Analytical biochemistry 20010101
Title: Molecular cloning and expression in yeast of 2,3-oxidosqualene-triterpenoid cyclases from Arabidopsis thaliana.
Journal: Plant molecular biology 20010101
Title: Localisation of lanosterol 14alpha-demethylase in round and elongated spermatids of the mouse testis: an immunoelectron microscopic and stereological study.
Journal: Pflugers Archiv : European journal of physiology 20010101
Title: Inhibitors of sterol biosynthesis and amphotericin B reduce the viability of pneumocystis carinii f. sp. carinii.
Journal: Antimicrobial agents and chemotherapy 20000601
Title: Synthesis of 25-aminosterols, new antifungal agents.
Journal: Bioorganic & medicinal chemistry letters 19990607
Title: Selective inhibition of mammalian lanosterol 14 alpha-demethylase by RS-21607 in vitro and in vivo.
Journal: Biochemistry 19940419
Title: Plant sterol biosynthesis: 7-oxo-obtusifoliol analogues as potential selective inhibitors of cytochrome P-450 dependent obtusifoliol 14 alpha-demethylase.
Journal: Biochimica et biophysica acta 19920423
Title: Synthesis, specificity, and antifungal activity of inhibitors of the Candida albicans delta 24-sterol methyltransferase.
Journal: Journal of medicinal chemistry 19920101
Title: Effects of environmentally encountered epoxides on mouse liver epoxide-metabolizing enzymes.
Journal: Biochemical pharmacology 19910601
Title: [Steroid alkaloids. 138(12). Chemical composition of the fruits and grains of Holarrhena mitis R. Br. (Apocynacea): alkaloids and unsaponifiable material].
Journal: Annales pharmaceutiques francaises 19721201
Title: 3',5'-cyclic adenosine monophosphate response element binding protein up-regulated cytochrome P450 lanosterol 14alpha-demethylase expression involved in follicle-stimulating hormone-induced mouse oocyte maturation.
Journal: Molecular endocrinology (Baltimore, Md.)
Title: Upadhyay A, et al. Lanosterol Suppresses the Aggregation and Cytotoxicity of Misfolded Proteins Linked with Neurodegenerative Diseases. Mol Neurobiol. 2018;55(2):1169-1182.
Title: Lee S, et al. Lanosterol influences cytoplasmic maturation of pig oocytes in vitro and improves preimplantation development of cloned embryos. Theriogenology. 2016;85(4):575-584.