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79902-63-9,MFCD00072007
Catalog No.:AA00327R
79902-63-9 | (1S,3R,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl 2,2-dimethylbutanoate
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1g
98%
in stock  
$7.00   $5.00
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5g
98%
in stock  
$19.00   $13.00
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10g
98%
in stock  
$34.00   $24.00
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25g
98%
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$62.00   $44.00
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  • Technical Information
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Technical Information
Catalog Number:
AA00327R
Chemical Name:
(1S,3R,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl 2,2-dimethylbutanoate
CAS Number:
79902-63-9
Molecular Formula:
C25H38O5
Molecular Weight:
418.5662
MDL Number:
MFCD00072007
IUPAC Name:
[(1S,3R,7S,8S,8aR)-8-[2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] 2,2-dimethylbutanoate
InChI:
InChI=1S/C25H38O5/c1-6-25(4,5)24(28)30-21-12-15(2)11-17-8-7-16(3)20(23(17)21)10-9-19-13-18(26)14-22(27)29-19/h7-8,11,15-16,18-21,23,26H,6,9-10,12-14H2,1-5H3/t15-,16-,18+,19+,20-,21-,23-/m0/s1
InChI Key:
RYMZZMVNJRMUDD-HGQWONQESA-N
SMILES:
CCC(C(=O)OC1CC(C)C=C2C1C(CCC1CC(O)CC(=O)O1)C(C=C2)C)(C)C
EC Number:
616-751-8
UNII:
AGG2FN16EV
Properties
Computed Properties
 
Complexity:
706  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
7  
Defined Bond Stereocenter Count:
0
Exact Mass:
418.272g/mol
Formal Charge:
0
Heavy Atom Count:
30  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0
Molecular Weight:
418.574g/mol
Monoisotopic Mass:
418.272g/mol
Rotatable Bond Count:
7  
Topological Polar Surface Area:
72.8A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
4.7  

Synonyms
 
MK 733 
MK-733 
Sinvacor 
Prestwick0_000865 
Prestwick1_000865 
Prestwick2_000865 
Prestwick3_000865 
Spectrum2_001671 
Spectrum3_000669 
Spectrum4_000632 
Spectrum5_001428 
AC1L1H1F 
SCHEMBL2471 
Denan 
CHEMBL1064 
BSPBio_000909 
BSPBio_002337 
KBioGR_001244 
KBioSS_002197 
MLS001304029 
MLS001333077 
MLS001333078 
MLS002154038 
MLS006011866 
Lipex 
ARONIS24119 
BIDD:GT0769 
DivK1c_006991 
SPECTRUM1504236 
SPBio_001881 
SPBio_002830 
BPBio1_001001 
GTPL2955 
Simvastatin (JP17/USP/INN) 
Simvastatin, analytical standard 
MK-733 
DTXSID0023581 
BCBcMAP01_000007 
KBio1_001935 
KBio2_002197 
KBio2_004765 
KBio2_007333 
KBio3_001557 
RYMZZMVNJRMUDD-HGQWONQESA- 
HMS1570N11 
HMS1922H13 
Simvastatine 
HMS2089D12 
HMS2093E06 
HMS2097N11 
HMS2231N22 
HMS3259B12 
HMS3676P08 
HMS3714N11 
Pharmakon1600-01504236 
ZINC3780893 
Tox21_110696 
Sivastin 
Tox21_300400 
BBL024390 
BDBM50139181 
CCG-39069 
MFCD00072007 
NSC633782 
NSC758706 
s1792 
SBB080618 
STK801938 
Lodales 
AKOS005111006 
AKOS015842733 
Simvastatin, >=97% (HPLC), solid 
Tox21_110696_1 
AC-1530 
AN-7250 
AT-7048 
CS-2269 
DB00641 
MCULE-8390617062 
Simvastatina 
NC00719 
NSC-633782 
NSC-758706 
MRF-0000729 
NCGC00017324-01 
NCGC00017324-02 
NCGC00017324-03 
NCGC00017324-04 
NCGC00017324-05 
NCGC00017324-07 
Simvastatinum 
NCGC00017324-08 
NCGC00017324-09 
NCGC00254418-01 
2,2-Dimethylbutanoic acid (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl ester 
AJ-45588 
BC203244 
Butanoic acid, 2,2-dimethyl-, (1S,3R,7S,8S,*aR)-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-(2-((2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl)-1-naphthalenyl ester 
butanoic acid, 2,2-dimethyl-,1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-[2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)-ethyl]-1-naphthalenyl ester, [1S-[1 alpha,3 alpha,7 beta,8 beta(2S*,4S*),-8a beta 
CPD000718785 
HY-17502 
Cholestat 
LS-46264 
SAM002589969 
SC-12666 
ST057168 
SBI-0206773.P001 
AB0069097 
ST2407853 
D00434 
J10128 
W-3044 
MK733 
Colemin 
28049-EP2269989A1 
28049-EP2269990A1 
28049-EP2270011A1 
28049-EP2270505A1 
28049-EP2272825A2 
28049-EP2272841A1 
28049-EP2277865A1 
28049-EP2280001A1 
28049-EP2280006A1 
28049-EP2281813A1 
Simovil 
28049-EP2284158A1 
28049-EP2287165A2 
28049-EP2287166A2 
28049-EP2292620A2 
28049-EP2295406A1 
28049-EP2295409A1 
28049-EP2295417A1 
28049-EP2295422A2 
28049-EP2298731A1 
28049-EP2298742A1 
Medipo 
28049-EP2298745A1 
28049-EP2298769A1 
28049-EP2298772A1 
28049-EP2298776A1 
28049-EP2298779A1 
28049-EP2301923A1 
28049-EP2301931A1 
28049-EP2301936A1 
28049-EP2305219A1 
28049-EP2305648A1 
Pantok 
28049-EP2308839A1 
28049-EP2308878A2 
28049-EP2314588A1 
96639-EP2287163A1 
96639-EP2305678A1 
99548-EP2270011A1 
99548-EP2298779A1 
99548-EP2301923A1 
99548-EP2301931A1 
AB00053395-07 
Simvastatin lactone 
AB00053395-08 
AB00053395-10 
AB00053395_11 
AB00053395_13 
902S639 
SR-05000001894-1 
SR-05000001894-2 
BRD-K22134346-001-05-8 
BRD-K22134346-001-11-6 
BRD-K22134346-001-15-7 
Labistatin 
Z1741982918 
Simvastatin, British Pharmacopoeia (BP) Reference Standard 
Simvastatin, European Pharmacopoeia (EP) Reference Standard 
Simvastatin, United States Pharmacopeia (USP) Reference Standard 
Simvastatin, Pharmaceutical Secondary Standard; Certified Reference Material 
Simvastatin for peak identification, European Pharmacopoeia (EP) Reference Standard 
(1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-Hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyly-2,2-dimethyl butanoate 
(1S,3R,7S,8S,8aR)-8-(2-((2R,4R)-4-Hydroxy-6-oxotetrahydro-2H-pyran-2-yl)ethyl)-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl 2,2-dimethylbu 
(1S,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl 2,2-dimethylbutanoate 
InChI=1/C25H38O5/c1-6-25(4,5)24(28)30-21-12-15(2)11-17-8-7-16(3)20(23(17)21)10-9-19-13-18(26)14-22(27)29-19/h7-8,11,15-16,18-21,23,26H,6,9-10,12-14H2,1-5H3/t15-,16-,18+,19+,20-,21-,23-/m0/s1 
Nivelipol 
Liponorm 
Vytorin 
Statin 
pepstatin 
simvastol 
Mixture Name 
Simvacor (TN) 
Simcard (TN) 
Simlup (TN) 
Simvastatin hydroxy acid 
Rendapid 
D0H0ND 
Simvastatin (JAN/USP/INN) 
Simvastatin [USAN:BAN:INN] 
MK733 
MK 733 
CID54454 
ACN-038331 
C25-H38-O5 
CS-O-05972 
CS-O-10912 
Vasotenal 
A8522 
D019821 
Simvastatin, 97%, inhibitor of HMG-CoA reductase - 1G 1g 
Zocor, Simlup, Simcard, Simvacor, Simvoget, Zorced, Simvastatin 
8-[2-(4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl)ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydro-1-naphthalenyl 2,2-dimethylbutanoate 
Velostatin 
Simvastatin 
Coledis 
Corolin 
Zocord 
Simvastatin (Zocor) 
Lipovas 
Rechol 
Zorced 
Simvastatine [French] 
Simvastatinum [Latin] 
Simvastatina [Spanish] 
Synvinolin 
Simcard 
Simvacor 
Simvoget 
Simlup 
(1S,3R,7S,8S,8aR)-8-(2-((2R,4R)-4-Hydroxy-6-oxotetrahydro-2H-pyran-2-yl)ethyl)-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl 2,2-dimethylbutanoate 
MK-0733 
UNII-AGG2FN16EV 
DRG-0320 
MK 0733 
CCRIS 7558 
Zocor 
HSDB 7208 
AGG2FN16EV 
2,2-Dimethylbutyric acid, 8-ester with (4R,6R)-6-(2-((1S,2S,6R,8S,8aR)-1,2,6,7,8,8a-hexahydro-8-hydroxy-2,6-dimethyl-1-naphthyl)ethyl)tetrahydro-4-hydroxy-2H-pyran-2-one 
L 644128-000U 
BRN 4768037 
CHEBI:9150 
(1S,3R,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl 2,2-dimethylbutanoate 
RYMZZMVNJRMUDD-HGQWONQESA-N 
C25H38O5 
Simcor 
simvastatin 
Simvastatin, 98% 
[(1S,3R,7S,8S,8aR)-8-[2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] 2,2-dimethylbutanoate 
Butanoic acid, 2,2-dimethyl-, (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl ester 
DSSTox_CID_3581 
DSSTox_RID_77090 
DSSTox_GSID_23581 
(1S,3R,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl 2,2-dimethylbutanoate 
Butanoic acid, 2,2-dimethyl-, (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-(2-((2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl)-1-naphthalenyl ester 
Zosta 
Simvast CR 
79902-63-9 
[(1S,3R,7S,8S,8aR)-8-[2-[(2R,4R)-4-hydroxy-6-oxo-tetrahydropyran-2-yl]ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] 2,2-dimethylbutanoate 
Butanoic acid, 2,2-dimethyl-, 1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-(2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl)-1-naphthalenyl ester, (1S-(1alpha,3alpha,7beta,8beta(2S*,4S*),8abeta))- 
SMR000718785 
Simvastatin [USAN:INN:BAN] 
Zocor (TN) 
Simvastatin, Compactin 
Simvastatin & Primycin 
SR-05000001894 
Kolestevan 
Lipinorm 
Zocor 
Modutrol 
Simvotin 
Sinvascor 
Valemia 
Eucor 
Nor-Vastina 
Simvastatin,(S) 
simvastatin predrug 
(+)-Simvastatin 
NCGC00016940-01 
Synvinolin 
Simvastatin(Zocor) 
inactive simvastatin 
8-[2-((2R,4R)-4-hydroxy-6-oxo(2H-3,4,5-trihydropyran-2-yl))ethyl](1S,7S,8S,3R, 8aR)-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthyl 2,2-dimethylbutanoate 
Simvastatin [USAN:USP:INN:BAN] 
TNP00259 
Prestwick_171 
CAS-79902-63-9 
KS-1113 
Spectrum_001717 
SpecPlus_000895 
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Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20181001

Title: The enhancement of cardiotoxicity that results from inhibiton of CYP 3A4 activity and hERG channel by berberine in combination with statins.

Journal: Chemico-biological interactions 20180925

Title: Characterization of simvastatin acid uptake by organic anion transporting polypeptide 3A1 (OATP3A1) and influence of drug-drug interaction.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20171201

Title: Combination of carvacrol with simvastatin improves the lipid-lowering efficacy and alleviates simvastatin side effects.

Journal: Journal of biochemical and molecular toxicology 20171201

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Journal: Chinese journal of integrative medicine 20170501

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Journal: Modern rheumatology 20140301

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Journal: Annals of hepatology 20140101

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Journal: Toxicology 20131004

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Journal: Fundamental & clinical pharmacology 20121201

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Journal: Shock (Augusta, Ga.) 20121101

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Journal: Journal of clinical pharmacology 20121101

Title: Interference in mevalonate pathway ameliorates homocysteine-induced endothelium-dysfunction.

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Journal: Science translational medicine 20121003

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Journal: The international journal of cardiovascular imaging 20121001

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Journal: Drug development and industrial pharmacy 20121001

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Journal: Amino acids 20121001

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Journal: Metabolism: clinical and experimental 20121001

Title: TNF-α modulates statin effects on secretion and expression of MCP-1, PAI-1 and adiponectin in 3T3-L1 differentiated adipocytes.

Journal: Cytokine 20121001

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Journal: Journal of chromatographic science 20121001

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Journal: International journal of clinical pharmacy 20121001

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Journal: QJM : monthly journal of the Association of Physicians 20121001

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Title: Differences in synthesis and absorption of cholesterol of two effective lipid-lowering therapies.

Journal: Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20121001

Title: Statins inhibit pulmonary artery smooth muscle cell proliferation by upregulation of HO-1 and p21WAF1.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20121001

Title: Serum nitric oxide synthase activity is a novel predictor of impaired vasorelaxation in rats.

Journal: Clinical and experimental pharmacology & physiology 20121001

Title: Simvastatin but not bezafibrate decreases plasma lipoprotein-associated phospholipase A₂ mass in type 2 diabetes mellitus: relevance of high sensitive C-reactive protein, lipoprotein profile and low-density lipoprotein (LDL) electronegativity.

Journal: European journal of internal medicine 20121001

Title: A time course investigation of the statin paradox among valvular interstitial cell phenotypes.

Journal: American journal of physiology. Heart and circulatory physiology 20121001

Title: Clinical benefits of ezetimibe use: is absence of proof, proof of absence?

Journal: Expert opinion on pharmacotherapy 20121001

Title: Benefits of pharmaceutical innovation: the case of simvastatin in Canada.

Journal: International journal of technology assessment in health care 20121001

Title: [Lipid therapy in daily routine].

Journal: Deutsche medizinische Wochenschrift (1946) 20121001

Title: Teratogenic risk of statins in pregnancy.

Journal: The Annals of pharmacotherapy 20121001

Title: [Effects of simvastatin on lipopolysaccharide induced α-subunit epithelial sodium channel mRNA in rat lung alveolar type II epithelial cells].

Journal: Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue 20121001

Title: Effect of an Ilex asprella root decoction on the related genes of lipid metabolism from chronic stress and hyperlipidemic fatty liver in rats.

Journal: Chinese medical journal 20121001

Title: Pregabalin and simvastatin: first report of a case of rhabdomyolysis.

Journal: P & T : a peer-reviewed journal for formulary management 20121001

Title: Effects of simvastatin on the expression of heme oxygenase-1 in human RPE cells.

Journal: Investigative ophthalmology & visual science 20120921

Title: Myopathy and possible intestinal dysfunction in a patient treated with colchicine and simvastatin.

Journal: The Medical journal of Australia 20120917

Title: HMG CoA reductase inhibitors, NSAIDs and risk of glioma.

Journal: International journal of cancer 20120915

Title: Effect of a high dose of simvastatin on muscle mitochondrial metabolism and calcium signaling in healthy volunteers.

Journal: Toxicology and applied pharmacology 20120915

Title: Role of simvastatin and/or antioxidant vitamins in therapeutic angiogenesis in experimental diabetic hindlimb ischemia: effects on capillary density, angiogenesis markers, and oxidative stress.

Journal: European journal of pharmacology 20120905

Title: Simvastatin evokes an unpredicted inhibition of β-adrenoceptor-mediated vasodilatation in porcine coronary artery.

Journal: European journal of pharmacology 20120905

Title: Ox-LDL-induced TGF-β1 production in human alveolar epithelial cells: involvement of the Ras/ERK/PLTP pathway.

Journal: Journal of cellular physiology 20120901

Title: No evidence for mevalonate shunting in moderately affected children with Smith-Lemli-Opitz syndrome.

Journal: Journal of inherited metabolic disease 20120901

Title: Interleukin-6 and cytochrome-P450, reason for concern?

Journal: Rheumatology international 20120901

Title: Importance of assessing the effect of statins on the function of high- density lipoproteins on coronary plaque.

Journal: Cardiovascular & hematological disorders drug targets 20120901

Title: Role of genetic factors in statins side-effects.

Journal: Cardiovascular & hematological disorders drug targets 20120901

Title: Charaterization of bumarsin, a 3-hydroxy-3-methylglutaryl-coenzyme reductase inhibitor from Mesobuthus martensii Karsch venom.

Journal: Toxicon : official journal of the International Society on Toxinology 20120901

Title: Effect of intensive lipid-lowering therapy on cardiovascular outcome in patients with and those without inflammatory joint disease.

Journal: Arthritis and rheumatism 20120901

Title: Statin pleiotropy prevents rho kinase-mediated intestinal epithelial barrier compromise induced by Blastocystis cysteine proteases.

Journal: Cellular microbiology 20120901

Title: Lipid-lowering therapy in chronic kidney disease: is there a role for ezetimibe?

Journal: Journal of renal care 20120901

Title: Simvastatin exerts cardioprotective effects and inhibits the activity of Rho-associated protein kinase in rats with metabolic syndrome.

Journal: Clinical and experimental pharmacology & physiology 20120901

Title: Effects of lipid-lowering treatment on platelet reactivity and platelet-leukocyte aggregation in diabetic patients without and with chronic kidney disease: a randomized trial.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20120901

Title: Comparison of the effects of different statins and doses on lipid levels in patients with diabetes: results from VOYAGER.

Journal: Nutrition, metabolism, and cardiovascular diseases : NMCD 20120901

Title: Selective induction of apoptosis by HMG-CoA reductase inhibitors in hepatoma cells and dependence on p53 expression.

Journal: Oncology reports 20120901

Title: miR-33 controls the expression of biliary transporters, and mediates statin- and diet-induced hepatotoxicity.

Journal: EMBO molecular medicine 20120901

Title: The serum metabolomic study of intervention effects of the traditional Chinese medicine Shexiang Baoxin Pill and a multi-component medicine polypill in the treatment of myocardial infarction in rats.

Journal: Molecular bioSystems 20120901

Title: Simvastatin reduces myocardial injury undergoing noncoronary artery cardiac surgery: a randomized controlled trial.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20120901

Title: The effect of simvastatin treatment on behavioral parameters, cognitive performance, and hippocampal morphology in rats fed a standard or a high-fat diet.

Journal: Behavioural pharmacology 20120901

Title: Commentary: simvastatin as the key to improving H. pylori eradication rates?

Journal: Alimentary pharmacology & therapeutics 20120901

Title: Simultaneous quantification of niacin and its three main metabolites in human plasma by LC-MS/MS.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20120901

Title: Combining human periodontal ligament cell membrane chromatography with online HPLC/MS for screening osteoplastic active compounds from Coptidis Rhizoma.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20120901

Title: Atorvastatin prevents dehydromonocrotaline-induced pulmonary hypertension in beagles.

Journal: Experimental lung research 20120901

Title: Efficacy of statins in combination with interferon therapy in multiple sclerosis: a meta-analysis.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20120901

Title: Concomitant use of pazopanib and simvastatin increases the risk of transaminase elevations in patients with cancer.

Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20120901

Title: Statins and new-onset diabetes: a retrospective longitudinal cohort study.

Journal: Clinical therapeutics 20120901

Title: Can statins reduce the inflammatory response associated with preterm birth in an animal model?

Journal: American journal of obstetrics and gynecology 20120901

Title: Beyond low-density lipoprotein cholesterol: why, who and when.

Journal: Singapore medical journal 20120901

Title: LDL S-homocysteinylation decrease in chronic kidney disease patients undergone lipid lowering therapy.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20120830

Title: Effect of Si-Miao-Yong-An on the stability of atherosclerotic plaque in a diet-induced rabbit model.

Journal: Journal of ethnopharmacology 20120830

Title: Neuroprotective potential of atorvastatin and simvastatin (HMG-CoA reductase inhibitors) against 6-hydroxydopamine (6-OHDA) induced Parkinson-like symptoms.

Journal: Brain research 20120830

Title: Rational formulation development and in vitro assessment of SMEDDS for oral delivery of poorly water soluble drugs.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20120815

Title: Critical role for integrin-β4 in the attenuation of murine acute lung injury by simvastatin.

Journal: American journal of physiology. Lung cellular and molecular physiology 20120815

Title: Myalgia while taking statins.

Journal: BMJ (Clinical research ed.) 20120814

Title: Clinical reasoning: a case of treatable spastic paraparesis.

Journal: Neurology 20120807

Title: Cost-effectiveness of statins revisited: lessons learned about the value of innovation.

Journal: The European journal of health economics : HEPAC : health economics in prevention and care 20120801

Title: Phase I studies on the safety, tolerability, pharmacokinetics and pharmacodynamics of SB-649868, a novel dual orexin receptor antagonist.

Journal: Journal of psychopharmacology (Oxford, England) 20120801

Title: Drug interaction profile for GSK2248761, a next generation non-nucleoside reverse transcriptase inhibitor.

Journal: British journal of clinical pharmacology 20120801

Title: Progenitor cell mobilizing treatments prevent experimental transplant arteriosclerosis.

Journal: The Journal of surgical research 20120801

Title: Pravastatin and simvastatin improves acetylsalicylic acid-mediated in vitro blood platelet inhibition.

Journal: European journal of clinical investigation 20120801

Title: Statin-induced immunomodulation alters peripheral invariant natural killer T-cell prevalence in hyperlipidemic patients.

Journal: Cardiovascular drugs and therapy 20120801

Title: 3-Hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor simvastatin ameliorates renal fibrosis through HOXA13-USAG-1 pathway.

Journal: Laboratory investigation; a journal of technical methods and pathology 20120801

Title: Statin medication in patients treated with antiepileptic drugs in Norway.

Journal: Pharmacoepidemiology and drug safety 20120801

Title: Naltrindole inhibits human multiple myeloma cell proliferation in vitro and in a murine xenograft model in vivo.

Journal: The Journal of pharmacology and experimental therapeutics 20120801

Title: Fate and transport of atorvastatin and simvastatin drugs during conventional wastewater treatment.

Journal: Chemosphere 20120801

Title: Mitochondrial dysfunction--a pharmacological target in Alzheimer's disease.

Journal: Molecular neurobiology 20120801

Title: The development, characterization, and application of an OATP1B1 inhibition assay in drug discovery.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20120801

Title: Commentary on 'simvastatin decreases free radicals formation in the human abdominal aortic aneurysm wall via NF-κB'.

Journal: European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery 20120801

Title: Randomised clinical trial: simvastatin as adjuvant therapy improves significantly the Helicobacter pylori eradication rate--a placebo-controlled study.

Journal: Alimentary pharmacology & therapeutics 20120801

Title: Shear stress modulates the expression of the atheroprotective protein Cx37 in endothelial cells.

Journal: Journal of molecular and cellular cardiology 20120801

Title: Statin therapy lowers muscle sympathetic nerve activity and oxidative stress in patients with heart failure.

Journal: American journal of physiology. Heart and circulatory physiology 20120801

Title: Changes to the statin prescribing policy in Belgium: potential impact in clinical and economic terms.

Journal: American journal of cardiovascular drugs : drugs, devices, and other interventions 20120801

Title: Simvastatin decreases free radicals formation in the human abdominal aortic aneurysm wall via NF-κB.

Journal: European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery 20120801

Title: Effects of statin treatments and polymorphisms in UGT1A1 and SLCO1B1 on serum bilirubin levels in Chinese patients with hypercholesterolaemia.

Journal: Atherosclerosis 20120801

Title: Chronic cough as a complication of treatment with statins: a case report.

Journal: Therapeutic advances in respiratory disease 20120801

Title: Simvastatin administration.

Journal: The American journal of nursing 20120801

Title: In vitro synergism of simvastatin and fluconazole against Candida species.

Journal: Revista do Instituto de Medicina Tropical de Sao Paulo 20120801

Title: Literature based drug interaction prediction with clinical assessment using electronic medical records: novel myopathy associated drug interactions.

Journal: PLoS computational biology 20120801

Title: Simvastatin and losartan differentially and synergistically inhibit atherosclerosis in apolipoprotein e(-/-) mice.

Journal: Korean circulation journal 20120801

Title: Collagen with simvastatin promotes cell metabolism in osteoblast-like SaOS-2 cells.

Journal: Journal of pharmacy & bioallied sciences 20120801

Title: Statins: A new era in local drug delivery.

Journal: Journal of pharmacy & bioallied sciences 20120801

Title: Pleiotropic effects of ezetimibe/simvastatin vs. high dose simvastatin.

Journal: International journal of cardiology 20120726

Title: Journal Club: a randomized, double-blind, placebo-controlled trial of simvastatin to treat Alzheimer disease.

Journal: Neurology 20120724

Title: Simvastatin mobilizes bone marrow stromal cells migrating to injured areas and promotes functional recovery after spinal cord injury in the rat.

Journal: Neuroscience letters 20120719

Title: Feeding, simvastatin, and linezolid.

Journal: American journal of respiratory and critical care medicine 20120715

Title: Ring finger protein 149 is an E3 ubiquitin ligase active on wild-type v-Raf murine sarcoma viral oncogene homolog B1 (BRAF).

Journal: The Journal of biological chemistry 20120706

Title: Concomitant administration of simvastatin with ivabradine in contrast to metoprolol intensifies slowing of heart rate in normo- and hypercholesterolemic rats.

Journal: Archives of medical science : AMS 20120704

Title: Beta-alanine (Carnosyn™) supplementation in elderly subjects (60-80 years): effects on muscle carnosine content and physical capacity.

Journal: Amino acids 20120701

Title: RhoB is associated with the anti-angiogenic effects of celiac patient transglutaminase 2-targeted autoantibodies.

Journal: Journal of molecular medicine (Berlin, Germany) 20120701

Title: Comparative efficacy and safety of fenofibrate/pravastatin plus ezetimibe triple therapy and simvastatin/ezetimibe dual therapy in type 2 diabetic patients with mixed hyperlipidaemia and cardiovascular disease.

Journal: Diabetes & vascular disease research 20120701

Title: Implementing a statin switching programme in primary care: patients' views and experiences.

Journal: British journal of clinical pharmacology 20120701

Title: Predictors of statin-induced regression of left anterior descending coronary artery wall thickness as measured by high-resolution transthoracic echocardiography.

Journal: Echocardiography (Mount Kisco, N.Y.) 20120701

Title: Simvastatin decreases invasiveness of human endometrial stromal cells.

Journal: Biology of reproduction 20120701

Title: Protective role of simvastatin on isolated rabbit atrioventricular node during experimental atrial fibrillation model: role in rate control of ventricular beats.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20120701

Title: Persistent use of against-label statin-fibrate combinations from 2003-2009 despite United States Food and Drug Administration dose restrictions.

Journal: Pharmacotherapy 20120701

Title: The clinical pharmacogenomics implementation consortium: CPIC guideline for SLCO1B1 and simvastatin-induced myopathy.

Journal: Clinical pharmacology and therapeutics 20120701

Title: Identical LDL-cholesterol lowering but non-identical effects on NF-κB activity: High dose simvastatin vs combination therapy with ezetimibe.

Journal: Atherosclerosis 20120701

Title: Hypertension in aortic stenosis: implications for left ventricular structure and cardiovascular events.

Journal: Hypertension (Dallas, Tex. : 1979) 20120701

Title: Deterioration of glucose homeostasis in type 2 diabetic patients one year after beginning of statins therapy.

Journal: Atherosclerosis 20120701

Title: Phosphorylation of endothelial NOS contributes to simvastatin protection against myocardial no-reflow and infarction in reperfused swine hearts: partially via the PKA signaling pathway.

Journal: Acta pharmacologica Sinica 20120701

Title: A mechanistic pharmacokinetic model to assess modified oral drug bioavailability post bariatric surgery in morbidly obese patients: interplay between CYP3A gut wall metabolism, permeability and dissolution.

Journal: The Journal of pharmacy and pharmacology 20120701

Title: Mediating effects of aryl-hydrocarbon receptor and RhoA in altering brain vascular integrity: the therapeutic potential of statins.

Journal: The American journal of pathology 20120701

Title: The ezetimibe controversy - can this be resolved by comparing the clinical trials with simvastatin and ezetimibe alone and together?

Journal: Expert opinion on pharmacotherapy 20120701

Title: Insertion-deletions in a FADS2 intron 1 conserved regulatory locus control expression of fatty acid desaturases 1 and 2 and modulate response to simvastatin.

Journal: Prostaglandins, leukotrienes, and essential fatty acids 20120701

Title: Cholesterol level goal attainment with statins: clinical management guideline recommendations versus management in actual clinical practice.

Journal: Pharmacotherapy 20120701

Title: Comparison of risk factor reduction and tolerability of a full-dose polypill (with potassium) versus low-dose polypill (polycap) in individuals at high risk of cardiovascular diseases: the Second Indian Polycap Study (TIPS-2) investigators.

Journal: Circulation. Cardiovascular quality and outcomes 20120701

Title: [Effects of Chinese herbal medicine Guanxinkang on expression of PPARγ-LXRα-ABCA1 pathway in ApoE-knockout mice with atherosclerosis].

Journal: Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20120701

Title: Oral alitretinoin: a review of the clinical pharmacokinetics and pharmacodynamics.

Journal: Expert review of clinical pharmacology 20120701

Title: Dissolution medium responsive simvastatin release from biodegradable apatite cements and the therapeutic effect in osteoporosis rats.

Journal: Journal of applied biomaterials & functional materials 20120626

Title: ACP Journal Club. Review: Perioperative statins reduce perioperative MI and AF in statin-naïve patients.

Journal: Annals of internal medicine 20120619

Title: Case 7-2012: a man with pain and weakness in the legs.

Journal: The New England journal of medicine 20120614

Title: Cholesterol metabolism differs after statin therapy according to the type of hyperlipemia.

Journal: Life sciences 20120606

Title: Niacin and statin combination therapy for atherosclerosis regression and prevention of cardiovascular disease events: reconciling the AIM-HIGH (Atherothrombosis Intervention in Metabolic Syndrome With Low HDL/High Triglycerides: Impact on Global Health Outcomes) trial with previous surrogate endpoint trials.

Journal: Journal of the American College of Cardiology 20120605

Title: Differential effect of the rs4149056 variant in SLCO1B1 on myopathy associated with simvastatin and atorvastatin.

Journal: The pharmacogenomics journal 20120601

Title: Implementation of a simple age-based strategy in the prevention of cardiovascular disease: the Polypill approach.

Journal: Journal of evaluation in clinical practice 20120601

Title: The effect of ezetimibe and simvastatin on hemostasis in patients with isolated hypercholesterolemia.

Journal: Fundamental & clinical pharmacology 20120601

Title: Prescribing high-dose lipid-lowering therapy early to avoid subsequent cardiovascular events: is this a cost-effective strategy?

Journal: European journal of preventive cardiology 20120601

Title: Cost-effectiveness of extended-release niacin/laropiprant added to a stable simvastatin dose in secondary prevention patients not at cholesterol goal in Germany.

Journal: The European journal of health economics : HEPAC : health economics in prevention and care 20120601

Title: Tubulointerstitial injury and the progression of chronic kidney disease.

Journal: Pediatric nephrology (Berlin, Germany) 20120601

Title: Potential role of statins on wound healing: review of the literature.

Journal: International wound journal 20120601

Title: Patient socioeconomic determinants for the choice of the cheapest molecule within a cluster: evidence from Belgian prescription data.

Journal: The European journal of health economics : HEPAC : health economics in prevention and care 20120601

Title: Therapeutic effects of a combinatorial treatment of simvastatin and bone marrow stromal cells on experimental embolic stroke.

Journal: Basic & clinical pharmacology & toxicology 20120601

Title: Statins inhibit monocyte chemotactic protein 1 expression in endometriosis.

Journal: Reproductive sciences (Thousand Oaks, Calif.) 20120601

Title: 3-hydroxy 3-methylglutaryl coenzyme A reductase inhibition impairs muscle regeneration.

Journal: Journal of cellular biochemistry 20120601

Title: Impact of CYP2D6 polymorphisms on the pharmacokinetics of lovastatin in Chinese subjects.

Journal: European journal of clinical pharmacology 20120601

Title: Neuroprotective effects of statins: evidence from preclinical and clinical studies.

Journal: Current treatment options in cardiovascular medicine 20120601

Title: Cholesterol level influences opioid signaling in cell models and analgesia in mice and humans.

Journal: Journal of lipid research 20120601

Title: Simvastatin attenuated cerebrovascular cell proliferation in the development of hypertension through Rho/Rho-kinase pathway.

Journal: Journal of cardiovascular pharmacology 20120601

Title: Effect of simvastatin on the osteogenetic behavior of alveolar osteoblasts and periodontal ligament cells.

Journal: Human cell 20120601

Title: Molecular pathways regulating macrophage polarization: implications for atherosclerosis.

Journal: Current atherosclerosis reports 20120601

Title: Short-term statin administration in hypercholesterolaemic rabbits resistant to postconditioning: effects on infarct size, endothelial nitric oxide synthase, and nitro-oxidative stress.

Journal: Cardiovascular research 20120601

Title: Spontaneous cervical epidural hematoma associated with thunderclap headache.

Journal: The journal of headache and pain 20120601

Title: A broadly applicable gene knockout system for the thermoacidophilic archaeon Sulfolobus islandicus based on simvastatin selection.

Journal: Microbiology (Reading, England) 20120601

Title: Anti-inflammatory effects of perioperative statin therapy.

Journal: Canadian journal of anaesthesia = Journal canadien d'anesthesie 20120601

Title: New agents promote neuroprotection in Parkinson's disease models.

Journal: CNS & neurological disorders drug targets 20120601

Title: PDGF-simvastatin delivery stimulates osteogenesis in heat-induced osteonecrosis.

Journal: Journal of dental research 20120601

Title: Mesenchymal stromal cell therapy and treatment of ischaemic disease.

Journal: Basic & clinical pharmacology & toxicology 20120601

Title: Diastolic function parameters are improved by the addition of simvastatin to enalapril-based treatment in hypertensive individuals.

Journal: Atherosclerosis 20120601

Title: A review of time courses and predictors of lipid changes with fenofibric acid-statin combination.

Journal: Cardiovascular drugs and therapy 20120601

Title: Simvastatin alleviates the progression of periapical lesions by modulating autophagy and apoptosis in osteoblasts.

Journal: Journal of endodontics 20120601

Title: Statin is a reasonable treatment option for patients with Polycystic Ovary Syndrome: a meta-analysis of randomized controlled trials.

Journal: Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 20120601

Title: Short-term therapy with simvastatin reduces inflammatory mediators and heart inflammation during the acute phase of experimental Chagas disease.

Journal: Memorias do Instituto Oswaldo Cruz 20120601

Title: Apoptosis, autophagy and ER stress in mevalonate cascade inhibition-induced cell death of human atrial fibroblasts.

Journal: Cell death & disease 20120601

Title: Reverse Takotsubo pattern stress cardiomyopathy in a male patient induced during dobutamine stress echocardiography.

Journal: Annals of the Academy of Medicine, Singapore 20120601

Title: Combined effects of the ATP-sensitive potassium channel opener pinacidil and simvastatin on pulmonary vascular remodeling in rats with monocrotaline-induced pulmonary arterial hypertension.

Journal: Die Pharmazie 20120601

Title: Effects of Wenxiao II decoction on the expression of MCP-1 and VCAM-1 in atherosclerotic rabbits.

Journal: Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 20120601

Title: The evaluation of analgesic effects of simvastatin, pravastatin and atorvastatin in hot plate test.

Journal: European review for medical and pharmacological sciences 20120601

Title: Pleiotropic effects of rimonabant and simvastatin on obesity associated multiple metabolic risk factors in rats.

Journal: European review for medical and pharmacological sciences 20120601

Title: Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.

Journal: Journal of medicinal chemistry 20120524

Title: Déjà vu all over again.

Journal: Circulation 20120522

Title: Lipids and lipoproteins and risk of different vascular events in the MRC/BHF Heart Protection Study.

Journal: Circulation 20120522

Title: Simvastatin maintains osteoblastic viability while promoting differentiation by partially regulating the expressions of estrogen receptors α.

Journal: The Journal of surgical research 20120515

Title: Familial hypercholesterolaemia.

Journal: BMJ (Clinical research ed.) 20120511

Title: Peripheral arterial disease of the lower extremities.

Journal: Archives of medical science : AMS 20120509

Title: The differential effects of statins on the metastatic behaviour of prostate cancer.

Journal: British journal of cancer 20120508

Title: Safety of long-term simvastatin discontinuation.

Journal: Lancet (London, England) 20120505

Title: Hyaluronic acid receptor CD44 deficiency is associated with decreased Cryptococcus neoformans brain infection.

Journal: The Journal of biological chemistry 20120504

Title: Activator protein-1 (AP-1) signalling in human atherosclerosis: results of a systematic evaluation and intervention study.

Journal: Clinical science (London, England : 1979) 20120501

Title: Potential cardiovascular consequences of switching from atorvastatin to generic simvastatin in the Netherlands.

Journal: Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation 20120501

Title: Statins improve outcome in murine models of intracranial hemorrhage and traumatic brain injury: a translational approach.

Journal: Journal of neurotrauma 20120501

Title: Co-administration of statins with cytochrome P450 3A4 inhibitors in a UK primary care population.

Journal: Pharmacoepidemiology and drug safety 20120501

Title: Simvastatin reduces VCAM-1 expression in human umbilical vein endothelial cells exposed to lipopolysaccharide.

Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20120501

Title: Therapeutic effect of local administration of low-dose simvastatin-conjugated gelatin hydrogel for fracture healing.

Journal: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20120501

Title: Influence of lipid composition and drug load on the In Vitro performance of self-nanoemulsifying drug delivery systems.

Journal: Journal of pharmaceutical sciences 20120501

Title: Structural changes of the heart during severe sepsis or septic shock.

Journal: Shock (Augusta, Ga.) 20120501

Title: Identifying a selective substrate and inhibitor pair for the evaluation of CYP2J2 activity.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20120501

Title: Development of a multiparametric cell-based protocol to screen and classify the hepatotoxicity potential of drugs.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20120501

Title: The effects of membrane cholesterol and simvastatin on red blood cell deformability and ATP release.

Journal: Microvascular research 20120501

Title: Co-amorphous simvastatin and glipizide combinations show improved physical stability without evidence of intermolecular interactions.

Journal: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20120501

Title: Prolonged exposure to insulin induces mitochondrion-derived oxidative stress through increasing mitochondrial cholesterol content in hepatocytes.

Journal: Endocrinology 20120501

Title: Genetic determinants of response to cardiovascular drugs.

Journal: Current opinion in cardiology 20120501

Title: Different signaling mechanisms regulating IL-6 expression by LPS between gingival fibroblasts and mononuclear cells: seeking the common target.

Journal: Clinical immunology (Orlando, Fla.) 20120501

Title: Preparation of injectable auto-forming alginate gel containing simvastatin with amorphous calcium phosphate as a controlled release medium and their therapeutic effect in osteoporosis model rat.

Journal: Journal of materials science. Materials in medicine 20120501

Title: Influence of ischemic core muscle fibers on surface depolarization potentials in superfused cardiac tissue preparations: a simulation study.

Journal: Medical & biological engineering & computing 20120501

Title: Simvastatin interactions with other drugs.

Journal: Expert opinion on drug safety 20120501

Title: Simvastatin ointment, a new treatment for skin inflammatory conditions.

Journal: Journal of dermatological science 20120501

Title: Barbarians at the gate.

Journal: Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation 20120501

Title: Levofloxacin-induced tendinopathy of the hip.

Journal: The Annals of pharmacotherapy 20120501

Title: A polypill for all? Critical review of the polypill literature for primary prevention of cardiovascular disease and stroke.

Journal: The Annals of pharmacotherapy 20120501

Title: Prediction of drug-target interactions and drug repositioning via network-based inference.

Journal: PLoS computational biology 20120501

Title: A clinically significant interaction between warfarin and simvastatin is unique to carriers of the CYP2C9*3 allele.

Journal: Pharmacogenomics 20120501

Title: Pravastatin and fenofibrate in combination (Pravafenix(®)) for the treatment of high-risk patients with mixed hyperlipidemia.

Journal: Expert review of cardiovascular therapy 20120501

Title: Novel missense variants in LCAT and APOB genes in an Italian kindred with familial lecithin:cholesterol acyltransferase deficiency and hypobetalipoproteinemia.

Journal: Journal of clinical lipidology 20120501

Title: Interleukin-8 in the pathogenesis of primary central nervous system lymphoma in association with HIV infection.

Journal: Hematology (Amsterdam, Netherlands) 20120501

Title: Underuse of statins in patients with atherosclerotic ischemic stroke in China.

Journal: Chinese medical journal 20120501

Title: [Effect of Lycium ruthenicum anthocyanins on atherosclerosis in mice].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20120501

Title: [Effects of simvastatin on expression of connective tissue growth factor in vitreous and retina of diabetic rats].

Journal: [Zhonghua yan ke za zhi] Chinese journal of ophthalmology 20120501

Title: Aberrant expression of FcγRIIIA (CD16) contributes to the development of atherosclerosis.

Journal: Gene 20120425

Title: Cardiovascular primary prevention: how high should we set the bar?

Journal: Archives of internal medicine 20120423

Title: Use of administrative data to estimate the incidence of statin-related rhabdomyolysis.

Journal: JAMA 20120418

Title: ACP Journal Club. Adding niacin to simvastatin did not improve clinical outcomes in patients with CV disease and dyslipidemia.

Journal: Annals of internal medicine 20120417

Title: Propiconazole-enhanced hepatic cell proliferation is associated with dysregulation of the cholesterol biosynthesis pathway leading to activation of Erk1/2 through Ras farnesylation.

Journal: Toxicology and applied pharmacology 20120415

Title: The SHARP trial: lessons learnt; answers and more questions!

Journal: International journal of cardiology 20120405

Title: Age-dependent rescue by simvastatin of Alzheimer's disease cerebrovascular and memory deficits.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20120404

Title: Lipid-altering efficacy of ezetimibe/simvastatin 10/20 mg compared to rosuvastatin 10 mg in high-risk patients with and without type 2 diabetes mellitus inadequately controlled despite prior statin monotherapy.

Journal: Cardiovascular therapeutics 20120401

Title: Simvastatin inhibits glucose-stimulated vascular smooth muscle cell migration involving increased expression of RhoB and a block of Ras/Akt signal.

Journal: Cardiovascular therapeutics 20120401

Title: Simultaneous determination of simvastatin, lovastatin and niacin in human plasma by LC-MS/MS and its application to a human pharmacokinetic study.

Journal: Biomedical chromatography : BMC 20120401

Title: Heterogeneity in simvastatin-induced cytotoxicity in AML is caused by differences in Ras-isoprenylation.

Journal: Leukemia 20120401

Title: Apolipoprotein A-I mimetic peptide D-4F promotes human endothelial progenitor cell proliferation, migration, adhesion though eNOS/NO pathway.

Journal: Molecular biology reports 20120401

Title: Bisphosphonates as antimyeloma drugs.

Journal: Leukemia 20120401

Title: Potent mechanism-based inhibition of CYP3A4 by imatinib explains its liability to interact with CYP3A4 substrates.

Journal: British journal of pharmacology 20120401

Title: Recent advances in cardiovascular aspects of polycystic ovary syndrome.

Journal: European journal of endocrinology 20120401

Title: Simvastatin inhibits cancer cell growth by inducing apoptosis correlated to activation of Bax and down-regulation of BCL-2 gene expression.

Journal: International journal of oncology 20120401

Title: Statins lower calcium-induced oxidative stress in isolated mitochondria.

Journal: Human & experimental toxicology 20120401

Title: MEK/Erk-based negative feedback mechanism involved in control of Steel Factor-triggered production of Krüppel-like factor 2 in mast cells.

Journal: Cellular signalling 20120401

Title: Oral simvastatin reduces the hypertensive response to air-jet stress.

Journal: Clinical and experimental pharmacology & physiology 20120401

Title: Diabetes and hypertension: is there a common metabolic pathway?

Journal: Current atherosclerosis reports 20120401

Title: Direct to consumer Internet advertising of statins: an assessment of safety.

Journal: Pharmacoepidemiology and drug safety 20120401

Title: Simvastatin delivery via inhalation attenuates airway inflammation in a murine model of asthma.

Journal: International immunopharmacology 20120401

Title: Effect of extended-release niacin on new-onset diabetes among hyperlipidemic patients treated with ezetimibe/simvastatin in a randomized controlled trial.

Journal: Diabetes care 20120401

Title: Occipital nerve block is effective in craniofacial neuralgias but not in idiopathic persistent facial pain.

Journal: The journal of headache and pain 20120401

Title: Interventions to improve anticoagulation with warfarin.

Journal: Therapeutic drug monitoring 20120401

Title: Bone morphogenetic proteins and degenerative disk disease.

Journal: Neurosurgery 20120401

Title: Hypolipidemic effect of aqueous extract of Carum carvi (black Zeera) seeds in diet induced hyperlipidemic rats.

Journal: Pakistan journal of pharmaceutical sciences 20120401

Title: Reversible dysphasia and statins.

Journal: Journal of Korean medical science 20120401

Title: Is statin-associated cognitive impairment clinically relevant? A narrative review and clinical recommendations.

Journal: The Annals of pharmacotherapy 20120401

Title: Effect of lipid lowering on new-onset atrial fibrillation in patients with asymptomatic aortic stenosis: the Simvastatin and Ezetimibe in Aortic Stenosis (SEAS) study.

Journal: American heart journal 20120401

Title: Long-term outcome after statin treatment in routine clinical practice: results from a prospective PCI cohort study.

Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20120401

Title: The influence of simvastatin in induced peritoneal fibrosis in rats by peritoneal dialysis solution with glucosis 4.25%.

Journal: Acta cirurgica brasileira 20120401

Title: [Effects of simvastatin on PI3K/AKT signaling pathway in human acute monocytic leukemia cell line SHI-1].

Journal: Zhongguo shi yan xue ye xue za zhi 20120401

Title: Sialyllactose in viral membrane gangliosides is a novel molecular recognition pattern for mature dendritic cell capture of HIV-1.

Journal: PLoS biology 20120401

Title: Krüppel-like factor 2 suppression by high glucose as a possible mechanism of diabetic vasculopathy.

Journal: Korean circulation journal 20120401

Title: NASH is an Inflammatory Disorder: Pathogenic, Prognostic and Therapeutic Implications.

Journal: Gut and liver 20120401

Title: The Effects of Combined Treatment with an HMG-CoA Reductase Inhibitor and PPARγ Agonist on the Activation of Rat Pancreatic Stellate Cells.

Journal: Gut and liver 20120401

Title: Intestinal Anastomosis by Use of a Memory-shaped Compression Anastomosis Clip (Hand CAC 30): Early Clinical Experience.

Journal: Journal of the Korean Society of Coloproctology 20120401

Title: Ageing influences the effect of pre-hypoxic administration of clonidine, an alpha₂-adrenoceptor agonist, on post-hypoxic vasomotricity.

Journal: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20120401

Title: [Effects of serum containing Tanyu Tongzhi formula on production of NO, caveolin-1 and eNOS in HUVECs injured by ox-LDL].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20120401

Title: [Simvastatin inhibits activation of hepatic stellate cells and promotes activation of adenosine monophosphate-activated protein kinase].

Journal: Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20120401

Title: Interleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studies.

Journal: Lancet (London, England) 20120331

Title: Effect of shear stress, statins and TNF-α on hemostatic genes in human endothelial cells.

Journal: Biochemical and biophysical research communications 20120330

Title: Simvastatin disrupts cytoskeleton and decreases cardiac fibroblast adhesion, migration and viability.

Journal: Toxicology 20120329

Title: Impact of QRS duration and morphology on the risk of sudden cardiac death in asymptomatic patients with aortic stenosis: the SEAS (Simvastatin and Ezetimibe in Aortic Stenosis) Study.

Journal: Journal of the American College of Cardiology 20120327

Title: ACP Journal Club. Simvastatin reduced major vascular events at 5 years in at-risk patients; benefits were maintained at 11 years.

Journal: Annals of internal medicine 20120320

Title: Pregnane X receptor regulates drug metabolism and transport in the vasculature and protects from oxidative stress.

Journal: Cardiovascular research 20120315

Title: Statins for age-related macular degeneration.

Journal: The Cochrane database of systematic reviews 20120314

Title: Case records of the Massachusetts General Hospital. Case 7-2012. A 79-year-old man with pain and weakness in the legs.

Journal: The New England journal of medicine 20120308

Title: Pitavastatin: a review of its use in the management of hypercholesterolaemia or mixed dyslipidaemia.

Journal: Drugs 20120305

Title: Utility of Lp-PLA2 in lipid-lowering therapy.

Journal: American journal of therapeutics 20120301

Title: Simvastatin improves morphological and functional recovery of sciatic nerve injury in Wistar rats.

Journal: Injury 20120301

Title: Increased expression of endothelial lipase in symptomatic and unstable carotid plaques.

Journal: Journal of neurology 20120301

Title: SLCO1B1 haplotypes are not associated with atorvastatin-induced myalgia in Brazilian patients with familial hypercholesterolemia.

Journal: European journal of clinical pharmacology 20120301

Title: Addition of simvastatin to cold storage solution prevents endothelial dysfunction in explanted rat livers.

Journal: Hepatology (Baltimore, Md.) 20120301

Title: Treatment with high-dose simvastatin inhibits geranylgeranylation in AML blast cells in a subset of AML patients.

Journal: Experimental hematology 20120301

Title: Antimigraine medication use and associated health care costs in employed patients.

Journal: The journal of headache and pain 20120301

Title: A risk score for predicting mortality in patients with asymptomatic mild to moderate aortic stenosis.

Journal: Heart (British Cardiac Society) 20120301

Title: Effect of simvastatin on the expression and regulation mechanism of apolipoprotein M.

Journal: International journal of molecular medicine 20120301

Title: Statin use in COPD patients is associated with a reduction in mortality: a national cohort study.

Journal: Primary care respiratory journal : journal of the General Practice Airways Group 20120301

Title: Daily and intermittent rosuvastatin 5 mg therapy in statin intolerant patients: an observational study.

Journal: Current medical research and opinion 20120301

Title: Muscle mitochondrial metabolism and calcium signaling impairment in patients treated with statins.

Journal: Toxicology and applied pharmacology 20120301

Title: Clarification of the pleiotropic effects of statins on mevalonate pathway and the feedback regulation of isoprenoids requires more comprehensive investigation.

Journal: Cell biochemistry and function 20120301

Title: Combined treatment of Aβ immunization with statin in a mouse model of Alzheimer's disease.

Journal: Journal of neuroimmunology 20120301

Title: Clinical pharmacokinetics and pharmacodynamics of vildagliptin.

Journal: Clinical pharmacokinetics 20120301

Title: Effects of simvastain and enamel matrix derivative on Portland cement with bismuth oxide-induced growth and odontoblastic differentiation in human dental pulp cells.

Journal: Journal of endodontics 20120301

Title: Liraglutide-associated acute pancreatitis.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20120301

Title: Towards safer and more predictable drug treatment--reflections from studies of the First BCPT Prize awardee.

Journal: Basic & clinical pharmacology & toxicology 20120301

Title: Statins for COPD: a challenge to conventional beliefs?

Journal: Primary care respiratory journal : journal of the General Practice Airways Group 20120301

Title: Evaluation of the effects of simvastatin in reduction of panel-reactive antibody (PRA) levels in patients with end-stage renal disease awaiting renal transplantation.

Journal: Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia 20120301

Title: Cell cycle arrest is not yet senescence, which is not just cell cycle arrest: terminology for TOR-driven aging.

Journal: Aging 20120301

Title: Secondary stroke prevention: patent foramen ovale, aortic plaque, and carotid stenosis.

Journal: European heart journal 20120301

Title: Use of direct renin inhibitor in an HIV positive subject.

Journal: Le infezioni in medicina : rivista periodica di eziologia, epidemiologia, diagnostica, clinica e terapia delle patologie infettive 20120301

Title: The role and clinical significance of high-sensitivity C-reactive protein in cardiovascular disease.

Journal: Korean circulation journal 20120301

Title: SLCO1B1 gene variability influences lipid-lowering efficacy on simvastatin therapy in Southern Brazilians.

Journal: Clinical chemistry and laboratory medicine 20120301

Title: Simvastatin inhibits sphingosylphosphorylcholine-induced differentiation of human mesenchymal stem cells into smooth muscle cells.

Journal: Experimental & molecular medicine 20120227

Title: The effects of statins on blood pressure: current knowledge and future perspectives.

Journal: Archives of medical science : AMS 20120227

Title: Effects of 4-week administration of simvastatin in different doses on heart rate and blood pressure after metoprolol injection in normocholesterolaemic and normotensive rats.

Journal: Archives of medical science : AMS 20120227

Title: The impact of statin therapy on long-term cardiovascular outcomes in an outpatient cardiology practice.

Journal: Archives of medical science : AMS 20120227

Title: Reduction in atherosclerotic events: a retrospective study in an outpatient cardiology practice.

Journal: Archives of medical science : AMS 20120227

Title: Relationship between paraoxonase and homocysteine: crossroads of oxidative diseases.

Journal: Archives of medical science : AMS 20120227

Title: Immunohistochemical Characterization of S100A6 in the Murine Ovary.

Journal: Acta histochemica et cytochemica 20120227

Title: [Application of human adipose-derived stromal cells in bone tissue engineering].

Journal: Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences 20120218

Title: Impact of out-of-pocket expenses on discontinuation of statin therapy: a cohort study in Finland.

Journal: Journal of clinical pharmacy and therapeutics 20120201

Title: Review of the literature and suggestions for the design of rodent survival studies for the identification of compounds that increase health and life span.

Journal: Age (Dordrecht, Netherlands) 20120201

Title: Risk factor levels, risk factor combinations, and residual coronary risk: population-based estimates for secondary prevention patients using statins.

Journal: European journal of preventive cardiology 20120201

Title: Multidrug donor preconditioning protects steatotic liver grafts against ischemia-reperfusion injury.

Journal: American journal of surgery 20120201

Title: Post-operative atrial fibrillation: a maze of mechanisms.

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 20120201

Title: Hepatotoxicity associated with statins: reports of idiosyncratic liver injury post-marketing.

Journal: Journal of hepatology 20120201

Title: Simvastatin attenuates intestinal fibrosis independent of the anti-inflammatory effect by promoting fibroblast/myofibroblast apoptosis in the regeneration/healing process from TNBS-induced colitis.

Journal: Digestive diseases and sciences 20120201

Title: Adverse events associated with individual statin treatments for cardiovascular disease: an indirect comparison meta-analysis.

Journal: QJM : monthly journal of the Association of Physicians 20120201

Title: Effects of combining simvastatin with rosiglitazone on inflammation, oxidant stress and ambulatory blood pressure in patients with the metabolic syndrome: the SIROCO study.

Journal: Diabetes, obesity & metabolism 20120201

Title: Naringin ameliorates atherogenic dyslipidemia but not hyperglycemia in rats with type 1 diabetes.

Journal: Journal of cardiovascular pharmacology 20120201

Title: Simvastatin protects human osteosarcoma cells from oxidative stress-induced apoptosis through mitochondrial-mediated signaling.

Journal: Molecular medicine reports 20120201

Title: Proprotein convertase substilisin/kexin type 9 antagonism reduces low-density lipoprotein cholesterol in statin-treated hypercholesterolemic nonhuman primates.

Journal: The Journal of pharmacology and experimental therapeutics 20120201

Title: Simvastatin suppresses apoptosis in vulnerable atherosclerotic plaques through regulating the expression of p(53), Bcl-2 and Bcl-xL.

Journal: Cardiovascular drugs and therapy 20120201

Title: The pleiotropic effects of statins in the prevention of atherosclerosis : Editorial to: 'Simvastatin suppresses apoptosis in vulnerable atherosclerotic plaques through regulating the expression of p53, Bcl-2 en Bcl-xL' by Weiwei Qin et al.

Journal: Cardiovascular drugs and therapy 20120201

Title: A short-term biomarker modulation study of simvastatin in women at increased risk of a new breast cancer.

Journal: Breast cancer research and treatment 20120201

Title: Effects of losartan and amlodipine alone or combined with simvastatin in hypertensive patients with nonalcoholic hepatic steatosis.

Journal: European journal of gastroenterology & hepatology 20120201

Title: Simvastatin ameliorates angiotensin II-induced endothelial dysfunction through restoration of Rho-BH4-eNOS-NO pathway.

Journal: Cardiovascular drugs and therapy 20120201

Title: Behind-the-counter statins: a silver bullet for reducing costs and increasing access?

Journal: Health services research 20120201

Title: A review of the rationale for additional therapeutic interventions to attain lower LDL-C when statin therapy is not enough.

Journal: Current atherosclerosis reports 20120201

Title: Accelerated atherosclerosis in systemic lupus erythematosus: role of proinflammatory cytokines and therapeutic approaches.

Journal: Current allergy and asthma reports 20120201

Title: The 719Arg variant of KIF6 and cardiovascular outcomes in statin-treated, stable coronary patients of the treating to new targets and incremental decrease in end points through aggressive lipid-lowering prospective studies.

Journal: Circulation. Cardiovascular genetics 20120201

Title: Explication of interactions between HMGCR isoform 2 and various statins through In silico modeling and docking.

Journal: Computers in biology and medicine 20120201

Title: Inappropriately high left-ventricular mass in asymptomatic mild-moderate aortic stenosis.

Journal: Journal of hypertension 20120201

Title: Ezetimibe/simvastatin: a guide to its clinical use in hypercholesterolemia.

Journal: American journal of cardiovascular drugs : drugs, devices, and other interventions 20120201

Title: Teaching an old dog new tricks: potential antiatherothrombotic use for statins.

Journal: The Journal of clinical investigation 20120201

Title: Monocyte tissue factor-dependent activation of coagulation in hypercholesterolemic mice and monkeys is inhibited by simvastatin.

Journal: The Journal of clinical investigation 20120201

Title: Acute renal failure after paliperidone overdose: a case report.

Journal: Journal of clinical psychopharmacology 20120201

Title: Treatment with simvastatin inhibits the formation of abdominal aortic aneurysms in rabbits.

Journal: Annals of vascular surgery 20120201

Title: Lack of pharmacokinetic interactions between dapagliflozin and simvastatin, valsartan, warfarin, or digoxin.

Journal: Advances in therapy 20120201

Title: Imperative to consider multiple initiatives to maximize prescribing efficiency from generic availability: case history from Abu Dhabi.

Journal: Expert review of pharmacoeconomics & outcomes research 20120201

Title: Multiple initiatives continue to enhance the prescribing efficiency for the proton pump inhibitors and statins in Scotland.

Journal: Expert review of pharmacoeconomics & outcomes research 20120201

Title: HMG-CoA reductase inhibitors (statins) reduce hypertrophic scar formation in a rabbit ear wounding model.

Journal: Plastic and reconstructive surgery 20120201

Title: Additional experimental evidence that statins protect against acute lung injury.

Journal: Respiratory care 20120201

Title: [Simvastatin indused chylothorax].

Journal: Revue de pneumologie clinique 20120201

Title: Effect of simvastatin on development of obliterative airway disease: an experimental study.

Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20120201

Title: Prostaglandin E1 dose-dependently promotes stability of atherosclerotic plaque in a rabbit model.

Journal: Canadian journal of physiology and pharmacology 20120201

Title: Stem cells in drug screening for neurodegenerative disease.

Journal: The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 20120201

Title: Acute rhabdomyolysis caused by combination therapy with atorvastatin and warfarin.

Journal: British journal of hospital medicine (London, England : 2005) 20120201

Title: Severe neutropenia in a renal transplant patient suggesting an interaction between mycophenolate and fenofibrate.

Journal: Current drug safety 20120201

Title: Statin related memory dysfunction in a Nigerian woman: a case report.

Journal: Current drug safety 20120201

Title: Explaining statin inhibition effectiveness of HMG-CoA reductase by quantum biochemistry computations.

Journal: Physical chemistry chemical physics : PCCP 20120128

Title: Simvastatin-mediated enhancement of long-term potentiation is driven by farnesyl-pyrophosphate depletion and inhibition of farnesylation.

Journal: Neuroscience 20120127

Title: Suppression of Gαs synthesis by simvastatin treatment of vascular endothelial cells.

Journal: The Journal of biological chemistry 20120120

Title: Mutant p53 disrupts mammary tissue architecture via the mevalonate pathway.

Journal: Cell 20120120

Title: Clinical implications of electrocardiographic left ventricular strain and hypertrophy in asymptomatic patients with aortic stenosis: the Simvastatin and Ezetimibe in Aortic Stenosis study.

Journal: Circulation 20120117

Title: The effect of statins on performance in the Morris water maze in guinea pig.

Journal: European journal of pharmacology 20120115

Title: Protection against osteoporosis by statins is linked to a reduction of oxidative stress and restoration of nitric oxide formation in aged and ovariectomized rats.

Journal: European journal of pharmacology 20120115

Title: Simvastatin administration reduces thromboxane production in subjects taking aspirin: links between aspirin resistance and thrombin generation.

Journal: International journal of cardiology 20120112

Title: [Nephrology].

Journal: Revue medicale suisse 20120111

Title: In brief: Ezetimibe/simvastatin (Vytorin) in chronic kidney disease.

Journal: The Medical letter on drugs and therapeutics 20120109

Title: Researchers still seek clinical benefit in raising levels of good cholesterol.

Journal: JAMA 20120104

Title: Lack of modulatory effect of simvastatin on indoxyl sulfate-induced activation of cultured endothelial cells.

Journal: Life sciences 20120102

Title: Effects of simvastatin on carotenoid status in plasma.

Journal: Nutrition, metabolism, and cardiovascular diseases : NMCD 20120101

Title: Impacts of lisinopril and lisinopril plus simvastatin on erythrocyte and plasma arginase, nitrite, and nitrate in hypertensive patients.

Journal: Journal of clinical pharmacology 20120101

Title: Simvastatin augments the efficacy of therapeutic angiogenesis induced by bone marrow-derived mesenchymal stem cells in a murine model of hindlimb ischemia.

Journal: Molecular biology reports 20120101

Title: Synergistic effect of liver X receptor activation and simvastatin on plaque regression and stabilization: an magnetic resonance imaging study in a model of advanced atherosclerosis.

Journal: European heart journal 20120101

Title: The effect of ezetimibe, administered alone or in combination with simvastatin, on lymphocyte cytokine release in patients with elevated cholesterol levels.

Journal: Journal of internal medicine 20120101

Title: Using genome-wide association studies to identify genes important in serious adverse drug reactions.

Journal: Annual review of pharmacology and toxicology 20120101

Title: [Specific considerations on the prescription and therapeutic interchange of statins].

Journal: Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria 20120101

Title: A comparative evaluation of mono-, di- and triglyceride of medium chain fatty acids by lipid/surfactant/water phase diagram, solubility determination and dispersion testing for application in pharmaceutical dosage form development.

Journal: Pharmaceutical research 20120101

Title: Inhibition of AMPK-dependent autophagy enhances in vitro antiglioma effect of simvastatin.

Journal: Pharmacological research 20120101

Title: Hypertriglyceridemia, Metabolic Syndrome, and Cardiovascular Disease in HIV-Infected Patients: Effects of Antiretroviral Therapy and Adipose Tissue Distribution.

Journal: International journal of vascular medicine 20120101

Title: Simvastatin protects osteoblast against H2O2-induced oxidative damage via inhibiting the upregulation of Nox4.

Journal: Molecular and cellular biochemistry 20120101

Title: Simvastatin reduces steroidogenesis by inhibiting Cyp17a1 gene expression in rat ovarian theca-interstitial cells.

Journal: Biology of reproduction 20120101

Title: Simvastatin improves final visual outcome in acute optic neuritis: a randomized study.

Journal: Multiple sclerosis (Houndmills, Basingstoke, England) 20120101

Title: Cardioprotective effects of low-dose combination therapy with a statin and an angiotensin receptor blocker in a rat myocardial infarction model.

Journal: Journal of cardiology 20120101

Title: Understanding postprandial inflammation and its relationship to lifestyle behaviour and metabolic diseases.

Journal: International journal of vascular medicine 20120101

Title: Simvastatin modulates the Alzheimer's disease-related gene seladin-1.

Journal: Journal of Alzheimer's disease : JAD 20120101

Title: Effect of chinese herbal drug-containing serum for activating-blood and dispelling-toxin on ox-LDL-induced inflammatory factors' expression in endothelial cells.

Journal: Chinese journal of integrative medicine 20120101

Title: Effects of simvastatin on osseointegration in a canine total hip arthroplasty model an experimental study: a novel molecular mechanism.

Journal: The Journal of arthroplasty 20120101

Title: Plasma lipid profiling across species for the identification of optimal animal models of human dyslipidemia.

Journal: Journal of lipid research 20120101

Title: Rapid improvement of a complex migrainous episode with sodium valproate in a patient with CADASIL.

Journal: The journal of headache and pain 20120101

Title: Simvastatin impairs ADP-stimulated respiration and increases mitochondrial oxidative stress in primary human skeletal myotubes.

Journal: Free radical biology & medicine 20120101

Title: Effect of simvastatin on the pharmacokinetics of anastrozole.

Journal: Breast cancer research and treatment 20120101

Title: Development of an injectable two-phase drug delivery system for sequential release of antiresorptive and osteogenic drugs.

Journal: Journal of biomedical materials research. Part B, Applied biomaterials 20120101

Title: Deciphering the pathways of death of Histoplasma capsulatum-infected macrophages: implications for the immunopathogenesis of early infection.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20120101

Title: The effect of simvastatin on asymmetric dimethylarginine and flow-mediated vasodilation after optimizing the LDL level: a randomized, placebo-controlled study.

Journal: Vascular pharmacology 20120101

Title: Ezetimibe alone and in combination lowers the concentration of small, dense low-density lipoproteins in type 2 diabetes mellitus.

Journal: Atherosclerosis 20120101

Title: Utilization and costs of lipid modifying therapies following health technology assessment for the new reimbursement scheme in Sweden.

Journal: Health policy (Amsterdam, Netherlands) 20120101

Title: Ezetimibe: its novel effects on the prevention and the treatment of cholesterol gallstones and nonalcoholic Fatty liver disease.

Journal: Journal of lipids 20120101

Title: Current State-of-Art and New Trends on Lipid Nanoparticles (SLN and NLC) for Oral Drug Delivery.

Journal: Journal of drug delivery 20120101

Title: Effect of posaconazole on the pharmacokinetics of simvastatin and midazolam in healthy volunteers.

Journal: Expert opinion on drug metabolism & toxicology 20120101

Title: Lipid lowering effect of Cinnamomum zeylanicum in hyperlipidaemic albino rabbits.

Journal: Pakistan journal of pharmaceutical sciences 20120101

Title: Signaling required for blood vessel maintenance: molecular basis and pathological manifestations.

Journal: International journal of vascular medicine 20120101

Title: The long-term effect of statins on the risk of new-onset diabetes mellitus in elderly Taiwanese patients with hypertension and dyslipidaemia: a retrospective longitudinal cohort study.

Journal: Drugs & aging 20120101

Title: Adverse event profiles of 5-fluorouracil and capecitabine: data mining of the public version of the FDA Adverse Event Reporting System, AERS, and reproducibility of clinical observations.

Journal: International journal of medical sciences 20120101

Title: A systematic review of economic evaluations of interventions to tackle cardiovascular disease in low- and middle-income countries.

Journal: BMC public health 20120101

Title: Increased LDL susceptibility to oxidation accelerates future carotid artery atherosclerosis.

Journal: Lipids in health and disease 20120101

Title: Atorvastatin treatment is effective when used in combination with mefloquine in an experimental cerebral malaria murine model.

Journal: Malaria journal 20120101

Title: Quantile-specific penetrance of genes affecting lipoproteins, adiposity and height.

Journal: PloS one 20120101

Title: Connecting the dots between PubMed abstracts.

Journal: PloS one 20120101

Title: Cholesterol-lowering drugs and incident open-angle glaucoma: a population-based cohort study.

Journal: PloS one 20120101

Title: Effects of bile-acid-binding resin (colestimide) on blood glucose and visceral fat in Japanese patients with type 2 diabetes mellitus and hypercholesterolemia: an open-label, randomized, case-control, crossover study.

Journal: Journal of diabetes and its complications 20120101

Title: Statins to treat Alzheimer's disease: an incomplete story.

Journal: Expert review of neurotherapeutics 20120101

Title: Acute antidepressant and anxiolytic effects of simvastatin and its mechanisms in rats.

Journal: Neurosciences (Riyadh, Saudi Arabia) 20120101

Title: Simvastatin modulates remodeling of Kv4.3 expression in rat hypertrophied cardiomyocytes.

Journal: International journal of biological sciences 20120101

Title: The role of lipid rafts in cancer cell adhesion and migration.

Journal: International journal of cell biology 20120101

Title: Curcumin prevents high fat diet induced insulin resistance and obesity via attenuating lipogenesis in liver and inflammatory pathway in adipocytes.

Journal: PloS one 20120101

Title: Lipid disorders in elderly hypertensive patients.

Journal: International journal of hypertension 20120101

Title: Regression of left ventricular mass following conversion from conventional hemodialysis to thrice weekly in-centre nocturnal hemodialysis.

Journal: BMC nephrology 20120101

Title: Evidence-based prediction of statin use with lipid-panel data from the National Health and Nutrition Examination Survey.

Journal: Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research 20120101

Title: Comparison of the diagnostic accuracy of di-22:6-bis(monoacylglycerol)phosphate and other urinary phospholipids for drug-induced phospholipidosis or tissue injury in the rat.

Journal: International journal of toxicology 20120101

Title: Development and validation of a smartphone heart rate acquisition application for health promotion and wellness telehealth applications.

Journal: International journal of telemedicine and applications 20120101

Title: Lack of effect of lowering LDL cholesterol on cancer: meta-analysis of individual data from 175,000 people in 27 randomised trials of statin therapy.

Journal: PloS one 20120101

Title: Preventive pharmacotherapy in type 2 diabetes mellitus.

Journal: Indian journal of endocrinology and metabolism 20120101

Title: Treatment for primary hypothyroidism: current approaches and future possibilities.

Journal: Drug design, development and therapy 20120101

Title: Managing atrial fibrillation in the elderly: critical appraisal of dronedarone.

Journal: Clinical interventions in aging 20120101

Title: Correspondence between general practitioner-reported medication use and timing of prescription dispensation.

Journal: Clinical epidemiology 20120101

Title: Perspectives of Targeting mTORC1-S6K1 in Cardiovascular Aging.

Journal: Frontiers in physiology 20120101

Title: Ezetimibe/simvastatin 10/40 mg versus atorvastatin 40 mg in high cardiovascular risk patients with primary hypercholesterolemia: a randomized, double-blind, active-controlled, multicenter study.

Journal: Lipids in health and disease 20120101

Title: MicroRNA-152 mediates DNMT1-regulated DNA methylation in the estrogen receptor α gene.

Journal: PloS one 20120101

Title: Simvastatin and atorvastatin attenuate VCAM-1 and uPAR expression on human endothelial cells and platelet surface expression of CD40 ligand.

Journal: Cardiology journal 20120101

Title: A role for VEGFR2 activation in endothelial responses caused by barrier disruptive OxPAPC concentrations.

Journal: PloS one 20120101

Title: Toxicities effects of pharmaceutical, olive mill and textile wastewaters before and after degradation by Pseudomonas putida mt-2.

Journal: Cancer cell international 20120101

Title: PPARs in Regulation of Paraoxonases: Control of Oxidative Stress and Inflammation Pathways.

Journal: PPAR research 20120101

Title: Mesenchymal stem cells and cardiovascular disease: a bench to bedside roadmap.

Journal: Stem cells international 20120101

Title: Changes in Lipids and Lipoproteins after Selective LDL Apheresis (7-Year Experience).

Journal: Cholesterol 20120101

Title: Small vessel cerebrovascular disease: the past, present, and future.

Journal: Stroke research and treatment 20120101

Title: Quality and safety of medication use in primary care: consensus validation of a new set of explicit medication assessment criteria and prioritisation of topics for improvement.

Journal: BMC clinical pharmacology 20120101

Title: Niacin extended-release/simvastatin combination therapy produces larger favorable changes in high-density lipoprotein particles than atorvastatin monotherapy.

Journal: Vascular health and risk management 20120101

Title: Brain insulin resistance and deficiency as therapeutic targets in Alzheimer's disease.

Journal: Current Alzheimer research 20120101

Title: Statins induce the accumulation of regulatory T cells in atherosclerotic plaque.

Journal: Molecular medicine (Cambridge, Mass.) 20120101

Title: Antihyperlipidemic activity of Salacia chinensis root extracts in triton-induced and atherogenic diet-induced hyperlipidemic rats.

Journal: Indian journal of pharmacology 20120101

Title: Increased atherothrombotic burden in patients with diabetes mellitus and acute coronary syndrome: a review of antiplatelet therapy.

Journal: Cardiology research and practice 20120101

Title: Cost-effectiveness of rosuvastatin in comparison with generic atorvastatin and simvastatin in a Swedish population at high risk of cardiovascular events.

Journal: ClinicoEconomics and outcomes research : CEOR 20120101

Title: First-in-man study of simvastatin-eluting stent in de novo coronary lesions: the SIMVASTENT study.

Journal: Circulation journal : official journal of the Japanese Circulation Society 20120101

Title: An anti-PCSK9 antibody reduces LDL-cholesterol on top of a statin and suppresses hepatocyte SREBP-regulated genes.

Journal: International journal of biological sciences 20120101

Title: The effect of statin therapy in stroke outcome: a double blind clinical trial.

Journal: International journal of preventive medicine 20120101

Title: Statin use and the presence of microalbuminuria. Results from the ERICABEL trial: a non-interventional epidemiological cohort study.

Journal: PloS one 20120101

Title: Immunological response as a source to variability in drug metabolism and transport.

Journal: Frontiers in pharmacology 20120101

Title: Monocyte gene expression signature of patients with early onset coronary artery disease.

Journal: PloS one 20120101

Title: Paroxysmal atrial fibrillation triggered by a monomorphic ventricular couplet in a patient with acute coronary syndrome.

Journal: Indian pacing and electrophysiology journal 20120101

Title: Mouse heart rate in a human: diagnostic mystery of an extreme tachyarrhythmia.

Journal: Indian pacing and electrophysiology journal 20120101

Title: Expression and localization of claudins-3 and -12 in transformed human brain endothelium.

Journal: Fluids and barriers of the CNS 20120101

Title: Loss of proteostatic control as a substrate for atrial fibrillation: a novel target for upstream therapy by heat shock proteins.

Journal: Frontiers in physiology 20120101

Title: The relation between serum lipids and lutein and zeaxanthin in the serum and retina: results from cross-sectional, case-control and case study designs.

Journal: Lipids in health and disease 20120101

Title: Changes in prescription patterns before and after reporting of the Ezetimibe and Simvastatin in Hypercholesterolemia Enhances Atherosclerosis Regression trial (ENHANCE) results and expected effects on low-density lipoprotein-cholesterol reduction.

Journal: Journal of clinical lipidology 20120101

Title: Cost effectiveness of strategies to combat cardiovascular disease, diabetes, and tobacco use in sub-Saharan Africa and South East Asia: mathematical modelling study.

Journal: BMJ (Clinical research ed.) 20120101

Title: Assessment of extracts from red yeast rice for herb-drug interaction by in-vitro and in-vivo assays.

Journal: Scientific reports 20120101

Title: Ask the doctor. After a heart attack six years ago, I went on Lipitor (atorvastatin) because my doctor said it was proven to reduce the risk of a second heart attack in high-risk people like me. Three years ago, I switched to a generic (simvastatin) to save money. Now that Lipitor is going generic, should I switch back? And can I be assured that the generic version will be as effective as brand-name Lipitor at preventing a second heart attack?

Journal: Harvard heart letter : from Harvard Medical School 20120101

Title: Effect of simvastatin on transforming growth factor beta-1-induced myofibroblast differentiation and collagen production in nasal polyp-derived fibroblasts.

Journal: American journal of rhinology & allergy 20120101

Title: Comparison of prescription drug costs in the United States and the United Kingdom, Part 1: statins.

Journal: Pharmacotherapy 20120101

Title: Postchallenge responses of nitrotyrosine and TNF-alpha during 75-g oral glucose tolerance test are associated with the presence of coronary artery diseases in patients with prediabetes.

Journal: Cardiovascular diabetology 20120101

Title: Recovery of normal hemodynamic activities after long-term medication in a patient with left internal carotid arterial occlusion.

Journal: Journal of Nippon Medical School = Nippon Ika Daigaku zasshi 20120101

Title: Therapeutic Potential of Moringa oleifera Leaves in Chronic Hyperglycemia and Dyslipidemia: A Review.

Journal: Frontiers in pharmacology 20120101

Title: Cardiac arrest due to lymphocytic colitis: a case report.

Journal: Journal of medical case reports 20120101

Title: Therapeutic benefit of treatment of stroke with simvastatin and human umbilical cord blood cells: neurogenesis, synaptic plasticity, and axon growth.

Journal: Cell transplantation 20120101

Title: Quinolinic Acid, an endogenous molecule combining excitotoxicity, oxidative stress and other toxic mechanisms.

Journal: International journal of tryptophan research : IJTR 20120101

Title: A different way of coronary lesion preparation: stentablation and rotastenting.

Journal: Clinical Medicine Insights. Cardiology 20120101

Title: Acidic polysaccharide extracts from Gastrodia Rhizomes suppress the atherosclerosis risk index through inhibition of the serum cholesterol composition in Sprague Dawley rats fed a high-fat diet.

Journal: International journal of molecular sciences 20120101

Title: Antioxidant-induced stress.

Journal: International journal of molecular sciences 20120101

Title: Statin therapy, myopathy and exercise--a case report.

Journal: Lipids in health and disease 20120101

Title: Gender difference following high cholesterol diet induced renal injury and the protective role of rutin and ascorbic acid combination in Wistar albino rats.

Journal: Lipids in health and disease 20120101

Title: Comparative mitochondrial proteomics: perspective in human diseases.

Journal: Journal of hematology & oncology 20120101

Title: Locally administrated perindopril improves healing in an ovariectomized rat tibial osteotomy model.

Journal: PloS one 20120101

Title: Effects of pioglitazone and/or simvastatin on circulating TNFα and adiponectin levels in insulin resistance.

Journal: Journal of immunotoxicology 20120101

Title: Regulation of G protein-coupled receptors by palmitoylation and cholesterol.

Journal: BMC biology 20120101

Title: Palmitoylation and membrane cholesterol stabilize μ-opioid receptor homodimerization and G protein coupling.

Journal: BMC cell biology 20120101

Title: Effects of bezafibrate on lipid and glucose metabolism in dyslipidemic patients with diabetes: the J-BENEFIT study.

Journal: Cardiovascular diabetology 20120101

Title: Attenuation of niacin-induced prostaglandin D(2) generation by omega-3 fatty acids in THP-1 macrophages and Langerhans dendritic cells.

Journal: Journal of inflammation research 20120101

Title: Rosuvastatin: a review of the pharmacology and clinical effectiveness in cardiovascular disease.

Journal: Clinical Medicine Insights. Cardiology 20120101

Title: Bone responses to simvastatin-loaded porous implant surfaces in an ovariectomized model.

Journal: The International journal of oral & maxillofacial implants 20120101

Title: [Statin-ezetimibe combination in hyperlipidemia treatment].

Journal: Casopis lekaru ceskych 20120101

Title: Intensity of statin therapy, achieved low-density lipoprotein cholesterol levels and cardiovascular outcomes in Japanese patients after coronary revascularization. Perspectives from the CREDO-Kyoto registry cohort-2.

Journal: Circulation journal : official journal of the Japanese Circulation Society 20120101

Title: The renoprotective actions of peroxisome proliferator-activated receptors agonists in diabetes.

Journal: PPAR research 20120101

Title: Omega-3 index and smoking in patients with acute ST-elevation myocardial infarction taking statins: a case-control study in Korea.

Journal: Lipids in health and disease 20120101

Title: Simvastatin represses translocation of Pseudomonas aeruginosa across Madin-Darby canine kidney cell monolayers.

Journal: The journal of medical investigation : JMI 20120101

Title: HERALD (health economics using routine anonymised linked data).

Journal: BMC medical informatics and decision making 20120101

Title: The use of mouse models for understanding the biology of down syndrome and aging.

Journal: Current gerontology and geriatrics research 20120101

Title: Interplaying factors that effect multiple sclerosis causation and sustenance.

Journal: ISRN neurology 20120101

Title: Beneficial metabolic effects of 2',3',5'-tri-acetyl-N6- (3-hydroxylaniline) adenosine in the liver and plasma of hyperlipidemic hamsters.

Journal: PloS one 20120101

Title: Statins but not aspirin reduce thrombotic risk assessed by thrombin generation in diabetic patients without cardiovascular events: the RATIONAL trial.

Journal: PloS one 20120101

Title: HDL proteome in hemodialysis patients: a quantitative nanoflow liquid chromatography-tandem mass spectrometry approach.

Journal: PloS one 20120101

Title: The evaluation of chinese therapeutic food for the treatment of moderate dyslipidemia.

Journal: Evidence-based complementary and alternative medicine : eCAM 20120101

Title: Use of warfarin in long-term care: a systematic review.

Journal: BMC geriatrics 20120101

Title: New insights into the role of peroxisome proliferator-activated receptors in regulating the inflammatory response after tissue injury.

Journal: PPAR research 20120101

Title: Is there a role for hypolipidaemic drug therapy in the prevention or treatment of microvascular complications of diabetes?

Journal: The open cardiovascular medicine journal 20120101

Title: Genomics of Dementia: APOE- and CYP2D6-Related Pharmacogenetics.

Journal: International journal of Alzheimer's disease 20120101

Title: Notch signals in the endothelium and cancer 'stem-like' cells: opportunities for cancer therapy.

Journal: Vascular cell 20120101

Title: The effect of antihypertensive drugs on endothelial function as assessed by flow-mediated vasodilation in hypertensive patients.

Journal: International journal of vascular medicine 20120101

Title: Hyperglycemia and endothelial dysfunction in atherosclerosis: lessons from type 1 diabetes.

Journal: International journal of vascular medicine 20120101

Title: Cholesterol depletion in adipocytes causes caveolae collapse concomitant with proteosomal degradation of cavin-2 in a switch-like fashion.

Journal: PloS one 20120101

Title: Clarithromycin-induced rhabdomyolysis: a case report.

Journal: International journal of general medicine 20120101

Title: Simvastatin blocks blood-brain barrier disruptions induced by elevated cholesterol both in vivo and in vitro.

Journal: International journal of Alzheimer's disease 20120101

Title: Abnormal barrier function in the pathogenesis of ichthyosis: therapeutic implications for lipid metabolic disorders.

Journal: Clinics in dermatology 20120101

Title: Effect of spinally administered simvastatin on the formalin-induced nociceptive response in mice.

Journal: Journal of pharmacological sciences 20120101

Title: Efficacy of short-term high-dose statin in preventing contrast-induced nephropathy: a meta-analysis of seven randomized controlled trials.

Journal: PloS one 20120101

Title: Aloe barbadensis Mill. formulation restores lipid profile to normal in a letrozole-induced polycystic ovarian syndrome rat model.

Journal: Pharmacognosy research 20120101

Title: Fungal biofilm resistance.

Journal: International journal of microbiology 20120101

Title: Cardiovascular events in patients received combined fibrate/statin treatment versus statin monotherapy: Acute Coronary Syndrome Israeli Surveys data.

Journal: PloS one 20120101

Title: The metabolic syndrome and risk of chronic kidney disease: pathophysiology and intervention strategies.

Journal: Journal of nutrition and metabolism 20120101

Title: A comparative clinical study of hypolipidemic efficacy of Amla (Emblica officinalis) with 3-hydroxy-3-methylglutaryl-coenzyme-A reductase inhibitor simvastatin.

Journal: Indian journal of pharmacology 20120101

Title: A comparative effect of atorvastatin with other statins in patients of hyperlipidemia.

Journal: Indian journal of pharmacology 20120101

Title: Role of Mitogen-Activated Protein Kinases in Myocardial Ischemia-Reperfusion Injury during Heart Transplantation.

Journal: Journal of transplantation 20120101

Title: Barriers to cardiovascular risk prevention and management in Germany--an analysis of the EURIKA study.

Journal: Vascular health and risk management 20120101

Title: Nitric oxide synthases and atrial fibrillation.

Journal: Frontiers in physiology 20120101

Title: Recurrent acute pancreatitis probably induced by rosuvastatin therapy: a case report.

Journal: Case reports in medicine 20120101

Title: Connexins and diabetes.

Journal: Cardiology research and practice 20120101

Title: Novel therapeutics in Alzheimer's disease.

Journal: International journal of Alzheimer's disease 20120101

Title: Anti-inflammatory effect of simvastatin in an experimental model of spinal cord trauma: involvement of PPAR-α.

Journal: Journal of neuroinflammation 20120101

Title: Mobilization of CD34+CXCR4+ stem/progenitor cells and the parameters of left ventricular function and remodeling in 1-year follow-up of patients with acute myocardial infarction.

Journal: Mediators of inflammation 20120101

Title: Low-dose fluvastatin prevents the functional alterations of endothelium induced by short-term cholesterol feeding in rabbit carotid artery.

Journal: TheScientificWorldJournal 20120101

Title: Atherosclerosis: an integrative East-west medicine perspective.

Journal: Evidence-based complementary and alternative medicine : eCAM 20120101

Title: Sulfotanshinone sodium injection for unstable angina pectoris: a systematic review of randomized controlled trials.

Journal: Evidence-based complementary and alternative medicine : eCAM 20120101

Title: Regulation of hepatic paraoxonase-1 expression.

Journal: Journal of lipids 20120101

Title: Nutrition and nonalcoholic Fatty liver disease: the significance of cholesterol.

Journal: International journal of hepatology 20120101

Title: An overview of the evidence and mechanisms of herb-drug interactions.

Journal: Frontiers in pharmacology 20120101

Title: Cardiovascular magnetic resonance in systemic hypertension.

Journal: Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance 20120101

Title: Different effects of farrerol on an OVA-induced allergic asthma and LPS-induced acute lung injury.

Journal: PloS one 20120101

Title: Intestinal microbiota shifts towards elevated commensal Escherichia coli loads abrogate colonization resistance against Campylobacter jejuni in mice.

Journal: PloS one 20120101

Title: Antibacterial activity of statins: a comparative study of atorvastatin, simvastatin, and rosuvastatin.

Journal: Annals of clinical microbiology and antimicrobials 20120101

Title: Treatment patterns and risk factor control in patients with and without metabolic syndrome in cardiac rehabilitation.

Journal: Vascular health and risk management 20120101

Title: A systematic review of xuezhikang, an extract from red yeast rice, for coronary heart disease complicated by dyslipidemia.

Journal: Evidence-based complementary and alternative medicine : eCAM 20120101

Title: Integrin signaling in cancer cell survival and chemoresistance.

Journal: Chemotherapy research and practice 20120101

Title: Lumbar degenerative disc disease: current and future concepts of diagnosis and management.

Journal: Advances in orthopedics 20120101

Title: Sensitive spectrophotometric determination of atenolol in pharmaceutical formulations using bromate-bromide mixture as an eco-friendly brominating agent.

Journal: Journal of analytical methods in chemistry 20120101

Title: A novel granulation non-solvent addition method containing hydrophilic and lipophilic drugs.

Journal: Acta poloniae pharmaceutica 20120101

Title: Functional foods and nutraceuticals in the primary prevention of cardiovascular diseases.

Journal: Journal of nutrition and metabolism 20120101

Title: A tool for evaluating the potential for cost-effective outcomes measurement.

Journal: International journal of general medicine 20120101

Title: Pathophysiological changes to the peritoneal membrane during PD-related peritonitis: the role of mesothelial cells.

Journal: Mediators of inflammation 20120101

Title: Reactive oxygen species and inhibitors of inflammatory enzymes, NADPH oxidase, and iNOS in experimental models of Parkinson's disease.

Journal: Mediators of inflammation 20120101

Title: The Emerging Role of TLR and Innate Immunity in Cardiovascular Disease.

Journal: Cardiology research and practice 20120101

Title: Public health concerns for anti-obesity medicines imported for personal use through the internet: a cross-sectional study.

Journal: BMJ open 20120101

Title: Differential effects of simvastatin on IL-13-induced cytokine gene expression in primary mouse tracheal epithelial cells.

Journal: Respiratory research 20120101

Title: Vitreo-retinal hemorrhage after thrombolysis in a patient with acute ischemic stroke: a case report.

Journal: Frontiers in neurology 20120101

Title: Impact of oral simvastatin therapy on acute lung injury in mice during pneumococcal pneumonia.

Journal: BMC microbiology 20120101

Title: In vivo imaging of choroidal angiogenesis using fluorescence-labeled cationic liposomes.

Journal: Molecular vision 20120101

Title: Quercetin and epigallocatechin gallate induce in vitro a dose-dependent stiffening and hyperpolarizing effect on the cell membrane of human mononuclear blood cells.

Journal: International journal of molecular sciences 20120101

Title: Regular exercise or changing diet does not influence aortic valve disease progression in LDLR deficient mice.

Journal: PloS one 20120101

Title: Effect of ursodeoxycholic Acid alone and ursodeoxycholic Acid plus domperidone on radiolucent gallstones and gallbladder contractility in humans.

Journal: Gastroenterology research and practice 20120101

Title: Discontinuation of statin therapy in older people: does a cancer diagnosis make a difference? An observational cohort study using data linkage.

Journal: BMJ open 20120101

Title: Dynamic compression of chondrocyte-agarose constructs reveals new candidate mechanosensitive genes.

Journal: PloS one 20120101

Title: Do statins improve outcomes in patients with asthma on inhaled corticosteroid therapy? A retrospective cohort analysis.

Journal: BMJ open 20120101

Title: Plasticity and mTOR: towards restoration of impaired synaptic plasticity in mTOR-related neurogenetic disorders.

Journal: Neural plasticity 20120101

Title: Inactivation of CDK/pRb pathway normalizes survival pattern of lymphoblasts expressing the FTLD-progranulin mutation c.709-1G>A.

Journal: PloS one 20120101

Title: Novel and often bizarre strategies in the treatment of periodontal disease.

Journal: Journal of Indian Society of Periodontology 20120101

Title: Reviewing the medical literature: five notable articles in general internal medicine from 2010 and 2011.

Journal: Open medicine : a peer-reviewed, independent, open-access journal 20120101

Title: Concomitant administration of different doses of simvastatin with ivabradine influence on PAI-1 and heart rate in normo- and hypercholesterolaemic rats.

Journal: TheScientificWorldJournal 20120101

Title: Cardiometabolic complications after androgen deprivation therapy in a man with prostate cancer: effects of 3 years intermittent testosterone supplementation.

Journal: Frontiers in endocrinology 20120101

Title: Diverse spectrum of presentation of coronary slow flow phenomenon: a concise review of the literature.

Journal: Cardiology research and practice 20120101

Title: Sterol lipid metabolism in down syndrome revisited: down syndrome is associated with a selective reduction in serum brassicasterol levels.

Journal: Current gerontology and geriatrics research 20120101

Title: The Effect of Statins and Other Cardiovascular Medication on Ischemia-Reperfusion Damage in a Human DIEP Flap Model: Theoretical and Epidemiological Considerations.

Journal: Journal of transplantation 20120101

Title: [Simvastatin influence on carotid atherosclerotic disease regression].

Journal: Srpski arhiv za celokupno lekarstvo 20120101

Title: The effectiveness and cost effectiveness of dark chocolate consumption as prevention therapy in people at high risk of cardiovascular disease: best case scenario analysis using a Markov model.

Journal: BMJ (Clinical research ed.) 20120101

Title: LDL-apheresis: technical and clinical aspects.

Journal: TheScientificWorldJournal 20120101

Title: Antioxidant action of mangrove polyphenols against gastric damage induced by absolute ethanol and ischemia-reperfusion in the rat.

Journal: TheScientificWorldJournal 20120101

Title: Effects of coadministered extended-release niacin/laropiprant and simvastatin on lipoprotein subclasses in patients with dyslipidemia.

Journal: Journal of clinical lipidology 20120101

Title: Effectiveness of lipid-lowering therapy with statins for secondary prevention of atherosclerosis--guidelines vs. reality.

Journal: Pharmacological reports : PR 20120101

Title: Transcriptional activation of low-density lipoprotein receptor gene by DJ-1 and effect of DJ-1 on cholesterol homeostasis.

Journal: PloS one 20120101

Title: Genome-wide study of gene variants associated with differential cardiovascular event reduction by pravastatin therapy.

Journal: PloS one 20120101

Title: Pathophysiology of portal hypertension and esophageal varices.

Journal: International journal of hepatology 20120101

Title: Immunohistochemical and histomorphological analysis of rat mammary tumors after simvastatin treatment.

Journal: Neoplasma 20120101

Title: Effect of levels of acetate on the mevalonate pathway of Borrelia burgdorferi.

Journal: PloS one 20120101

Title: Acute pancreatitis induced by methimazole therapy.

Journal: Case reports in gastroenterology 20120101

Title: Sterol intermediates of cholesterol biosynthesis inhibit hair growth and trigger an innate immune response in cicatricial alopecia.

Journal: PloS one 20120101

Title: Mortality and morbidity of lowering low-density lipoprotein cholesterol with simvastatin.

Journal: The National medical journal of India 20120101

Title: [Effects of acidification and alkalinization agents on statins-induced muscle toxicity].

Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20120101

Title: Anesthetic Considerations in Hepatectomies under Hepatic Vascular Control.

Journal: HPB surgery : a world journal of hepatic, pancreatic and biliary surgery 20120101

Title: Relationship between lipid and lipoprotein metabolism in trimesters of pregnancy in Nigerian women: Is pregnancy a risk factor?

Journal: Journal of natural science, biology, and medicine 20120101

Title: [The influence of ezetimibe and simvaststin on platelet aggregation and protein c system in patients with coronary heart disease and hypercholesterolemia].

Journal: Klinicheskaia meditsina 20120101

Title: Ezetimibe and simvastatin reduce cholesterol levels in zebrafish larvae fed a high-cholesterol diet.

Journal: Cholesterol 20120101

Title: Mipomersen: evidence-based review of its potential in the treatment of homozygous and severe heterozygous familial hypercholesterolemia.

Journal: Core evidence 20120101

Title: Genetics Techniques for Thermococcus kodakarensis.

Journal: Frontiers in microbiology 20120101

Title: Barrett's Esophagus: Emerging Knowledge and Management Strategies.

Journal: Pathology research international 20120101

Title: Atherosclerotic disease and risk factor modification in Saudi Arabia: a call to action.

Journal: Vascular health and risk management 20120101

Title: CSF T-Tau/Aβ42 predicts white matter microstructure in healthy adults at risk for Alzheimer's disease.

Journal: PloS one 20120101

Title: Simvastatin reduces endotoxin-induced acute lung injury by decreasing neutrophil recruitment and radical formation.

Journal: PloS one 20120101

Title: Selected statins produce rapid spinal motor neuron loss in vitro.

Journal: BMC musculoskeletal disorders 20120101

Title: Versatile Genetic Tool Box for the Crenarchaeote Sulfolobus acidocaldarius.

Journal: Frontiers in microbiology 20120101

Title: Economic evaluation of statins in high-risk patients treated for primary and secondary prevention of cardiovascular disease in Greece.

Journal: ClinicoEconomics and outcomes research : CEOR 20120101

Title: Statin treatment increases lifespan and improves cardiac health in Drosophila by decreasing specific protein prenylation.

Journal: PloS one 20120101

Title: Doxycycline stabilizes vulnerable plaque via inhibiting matrix metalloproteinases and attenuating inflammation in rabbits.

Journal: PloS one 20120101

Title: Statin therapy in critical illness: an international survey of intensive care physicians' opinions, attitudes and practice.

Journal: BMC clinical pharmacology 20120101

Title: The importance of LDL and cholesterol metabolism for prostate epithelial cell growth.

Journal: PloS one 20120101

Title: Bilateral gluteal compartment syndrome following right total knee revision: a case report.

Journal: The Ochsner journal 20120101

Title: Effect of HMG-CoA-reductase inhibitor on DNA synthesis and free radical oxidation in the gastric mucosa under normal conditions and during indometacin-induced ulcerative process in the stomach of albino mice.

Journal: Bulletin of experimental biology and medicine 20120101

Title: Metabolomics reveals amino acids contribute to variation in response to simvastatin treatment.

Journal: PloS one 20120101

Title: Shengjie Tongyu Granule Inhibits Vascular Remodeling in ApoE-Gene-Knockout Mice.

Journal: Evidence-based complementary and alternative medicine : eCAM 20120101

Title: Potential hepato-protective effect of α-tocopherol or simvastatin in aged rats.

Journal: Pharmacological reports : PR 20120101

Title: Atorvastatin and simvastatin, but not pravastatin, up-regulate LPS-induced MMP-9 expression in macrophages by regulating phosphorylation of ERK and CREB.

Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20120101

Title: Statins affect the presentation of endothelial chemokines by targeting to multivesicular bodies.

Journal: PloS one 20120101

Title: Randomized Polypill crossover trial in people aged 50 and over.

Journal: PloS one 20120101

Title: ABO-incompatible kidney transplantation: first cases in Turkey.

Journal: Transplantation proceedings 20120101

Title: Simvastatin reduces endothelial NOS: caveolin-1 ratio but not the phosphorylation status of eNOS in vivo.

Journal: Journal of atherosclerosis and thrombosis 20120101

Title: Solubility enhancement of simvastatin: a review.

Journal: Acta poloniae pharmaceutica 20120101

Title: Preparation and statistical optimization of alginate based stomach specific floating microcapsules of simvastatin.

Journal: Acta poloniae pharmaceutica 20120101

Title: The effects of simvastatin or interferon-α on infectivity of human norovirus using a gnotobiotic pig model for the study of antivirals.

Journal: PloS one 20120101

Title: A survey of the FDA's AERS database regarding muscle and tendon adverse events linked to the statin drug class.

Journal: PloS one 20120101

Title: The effects of vitamin E-coated membrane dialyzer compared to simvastatin in patients on chronic hemodialysis.

Journal: Renal failure 20120101

Title: Heart-type fatty acid binding protein is associated with proteinuria in obesity.

Journal: PloS one 20120101

Title: Paracetamol and simvastatin: a potential interaction resulting in hepatotoxicity.

Journal: Medicina (Kaunas, Lithuania) 20120101

Title: The influence of simvastatin in rats mandible and femur bone mass under Freund's adjuvant arthritis.

Journal: Stomatologija 20120101

Title: Behavioral interactions of simvastatin and fluoxetine in tests of anxiety and depression.

Journal: Neuropsychiatric disease and treatment 20120101

Title: Statins and selective inhibition of Rho kinase protect small conductance calcium-activated potassium channel function (K(Ca)2.3) in cerebral arteries.

Journal: PloS one 20120101

Title: Cardioprotective potential of simvastatin in the hyperhomocysteinemic rat heart.

Journal: Journal of advanced pharmaceutical technology & research 20120101

Title: Patient with hypertriglyceridemia, type 2 diabetes, and chronic kidney disease treated with atorvastatin and omega-3 Fatty Acid ethyl esters.

Journal: The open cardiovascular medicine journal 20120101

Title: Potential drug-drug interactions in prescriptions to patients over 45 years of age in primary care, southern Brazil.

Journal: PloS one 20120101

Title: The effects of simvastatin on the pharmacokinectics of sitagliptin.

Journal: Journal of population therapeutics and clinical pharmacology = Journal de la therapeutique des populations et de la pharamcologie clinique 20120101

Title: Experimental evaluation of analgesic and anti-inflammatory activity of simvastatin and atorvastatin.

Journal: Indian journal of pharmacology 20120101

Title: Simvastatin attenuates contrast-induced nephropathy through modulation of oxidative stress, proinflammatory myeloperoxidase, and nitric oxide.

Journal: Oxidative medicine and cellular longevity 20120101

Title: Hypotensive effect of atorvastatin in hypertensive patients: the association among flow-mediated dilation, oxidative stress and endothelial dysfunction.

Journal: Archives of medical science : AMS 20111231

Title: IMproving the imPlemEntation of cuRrent guidelines for the mAnagement of major coronary hearT disease rIsk factors by multifactorial interVEntion. The IMPERATIVE renal analysis.

Journal: Archives of medical science : AMS 20111231

Title: Lipids, blood pressure, kidney - what was new in 2011?

Journal: Archives of medical science : AMS 20111231

Title: Comparative effects of high and low-dose simvastatin on prostate epithelial cells: the role of LDL.

Journal: European journal of pharmacology 20111230

Title: Simvastatin induces the expression of hemeoxygenase-1 against ischemia-reperfusion injury on the testes in rats.

Journal: Toxicology letters 20111215

Title: Niacin in patients with low HDL cholesterol levels receiving intensive statin therapy.

Journal: The New England journal of medicine 20111215

Title: PTU induction provide quick screening of hypo and hyperlipidemia.

Journal: Pakistan journal of biological sciences : PJBS 20111215

Title: Effects on 11-year mortality and morbidity of lowering LDL cholesterol with simvastatin for about 5 years in 20,536 high-risk individuals: a randomised controlled trial.

Journal: Lancet (London, England) 20111210

Title: Statins and safety: can we finally be reassured?

Journal: Lancet (London, England) 20111210

Title: Bisphosphonates: beyond prevention of bone metastases.

Journal: Journal of the National Cancer Institute 20111207

Title: Statins for multiple sclerosis.

Journal: The Cochrane database of systematic reviews 20111207

Title: Incorporation of economic evidence in the Dutch guideline 'cardiovascular risk management'.

Journal: Journal of evaluation in clinical practice 20111201

Title: Effects of simvastatin on osseointegration in a canine total hip arthroplasty model: an experimental study.

Journal: The Journal of arthroplasty 20111201

Title: Can simvastatin improve erectile function and health-related quality of life in men aged >40 years with erectile dysfunction? Rationale and design of the Erectile Dysfunction and Statins (EDS) Trial [ISRCTN66772971](1).

Journal: BJU international 20111201

Title: Lichen planus pemphigoides induced by a weight reduction drug.

Journal: Cutaneous and ocular toxicology 20111201

Title: Dissection of the posterior inferior cerebellar artery in the hypereosinophilic syndrome.

Journal: Journal of neurology 20111201

Title: The interactions of age, genetics, and disease severity on tacrolimus dosing requirements after pediatric kidney and liver transplantation.

Journal: European journal of clinical pharmacology 20111201

Title: Practice variation in a longitudinal perspective: a multilevel analysis of the prescription of simvastatin in general practices between 2003 and 2009.

Journal: European journal of clinical pharmacology 20111201

Title: Antinociception and anti-inflammation induced by simvastatin in algesiometric assays in mice.

Journal: Basic & clinical pharmacology & toxicology 20111201

Title: Effect of cryogrinding on chemical stability of the sparingly water-soluble drug furosemide.

Journal: Pharmaceutical research 20111201

Title: The influence of dosing time, variable compliance and circadian low-density lipoprotein production on the effect of simvastatin: simulations from a pharmacokinetic-pharmacodynamic model.

Journal: Basic & clinical pharmacology & toxicology 20111201

Title: Simvastatin administration ameliorates neurobehavioral consequences of subarachnoid hemorrhage in the rat.

Journal: Journal of neurotrauma 20111201

Title: Impact of diabetes on postinfarction heart failure and left ventricular remodeling.

Journal: Current heart failure reports 20111201

Title: Human embryonic stem cell derived hepatocyte-like cells as a tool for in vitro hazard assessment of chemical carcinogenicity.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20111201

Title: Simvastatin reduces tumor cell adhesion to human peritoneal mesothelial cells by decreased expression of VCAM-1 and β1 integrin.

Journal: International journal of oncology 20111201

Title: Regulation of apoptosis in human melanoma and neuroblastoma cells by statins, sodium arsenite and TRAIL: a role of combined treatment versus monotherapy.

Journal: Apoptosis : an international journal on programmed cell death 20111201

Title: Familial hypercholesterolemia: present and future management.

Journal: Current cardiology reports 20111201

Title: Novel CYP3A4 intron 6 single nucleotide polymorphism is associated with simvastatin-mediated cholesterol reduction in the Rotterdam Study.

Journal: Pharmacogenetics and genomics 20111201

Title: Altered fibrin clot properties in patients with retinal vein occlusion.

Journal: Journal of thrombosis and haemostasis : JTH 20111201

Title: Successful re-challenge of daptomycin therapy after initial rhabdomyolysis with co-administration of simvastatin.

Journal: International journal of antimicrobial agents 20111201

Title: Hypolipidemic and anti-inflammatory properties of Abacopterin A from Abacopteris penangiana in high-fat diet-induced hyperlipidemia mice.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20111201

Title: Cholesterol-lowering therapy for the treatment of nonalcoholic fatty liver disease: an update.

Journal: Current opinion in lipidology 20111201

Title: Drug utilization patterns and cardiovascular outcomes in elderly patients newly initiated on atorvastatin or simvastatin.

Journal: The American journal of geriatric pharmacotherapy 20111201

Title: Preparation and in vitro evaluation of simvastatin ethosome.

Journal: Artificial cells, blood substitutes, and immobilization biotechnology 20111201

Title: Effects of pioglitazone versus simvastatin on biomarkers of inflammation in patients on high cardiovascular risk.

Journal: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20111201

Title: Lipid lowering in patients with chronic kidney disease: a SHARP turn in the wrong direction?

Journal: European journal of cardiovascular prevention and rehabilitation : official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology 20111201

Title: [Effects of different statins, ezetimibe/simvastatin combination on hsCRP levels in unstable angina pectoris and non-ST elevation myocardial infarction patients: a randomized trial].

Journal: Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology 20111201

Title: Non-adherence to lipid-lowering therapies: a need for more studies to evaluate reasons for medication non-adherence.

Journal: International journal of clinical practice 20111201

Title: Intestinal sterol transporters and cholesterol absorption inhibition.

Journal: Current opinion in lipidology 20111201

Title: Simvastatin pretreatment prevents ambient particle-induced lung injury in mice.

Journal: Inhalation toxicology 20111201

Title: Simvastatin-induced myopathy with concomitant use of cyclosporine: case report.

Journal: International journal of clinical pharmacology and therapeutics 20111201

Title: Lipid-lowering drugs as primary prevention in general practice: do patients reach guideline goals and continue treatment? ADDITION Denmark.

Journal: Scandinavian journal of primary health care 20111201

Title: Fatal rhabdomyolysis in a patient with liver cirrhosis after switching from simvastatin to fluvastatin.

Journal: Journal of Korean medical science 20111201

Title: Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).

Journal: PLoS computational biology 20111201

Title: Phospholipase PLA2G7, associated with aggressive prostate cancer, promotes prostate cancer cell migration and invasion and is inhibited by statins.

Journal: Oncotarget 20111201

Title: Is it OK to eat or drink grapefruit products when I'm taking a statin?

Journal: The Johns Hopkins medical letter health after 50 20111201

Title: Low density lipoprotein cholesterol target goal attainment rate in korean patients with diabetes.

Journal: Diabetes & metabolism journal 20111201

Title: Low Density Lipoprotein Cholesterol Target Goal Attainment Rate and Physician Perceptions about Target Goal Achievement in Korean Patients with Diabetes.

Journal: Diabetes & metabolism journal 20111201

Title: Very Late Stent Thrombosis due to Neointimal Rupture After Paclitaxel-Eluting Stent Implantation.

Journal: Korean circulation journal 20111201

Title: NCI's provocative questions on cancer: some answers to ignite discussion.

Journal: Oncotarget 20111201

Title: Effects of simvastatin gel on bone regeneration in alveolar defects in miniature pigs.

Journal: Chinese medical journal 20111201

Title: Comparison of simvastatin with Eugenia Jambolana fruit pulp in their effects on alanine transferase, aspartate aminotransferase and creatinine phosphokinase levels of hyperlipidaemic rats.

Journal: JPMA. The Journal of the Pakistan Medical Association 20111201

Title: [Achievement of therapeutic target in subjects on statin treatment in clinical practice. Results of the STAR (Statins Target Assessment in Real practice) study].

Journal: Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace 20111201

Title: What are the Evidence Based Public Health Interventions for Prevention and Control of NCDs in Relation to India?

Journal: Indian journal of community medicine : official publication of Indian Association of Preventive & Social Medicine 20111201

Title: Exploiting the diversity of the heat-shock protein family for primary and secondary tauopathy therapeutics.

Journal: Current neuropharmacology 20111201

Title: Therapeutic interventions targeting Beta amyloid pathogenesis in an aging dog model.

Journal: Current neuropharmacology 20111201

Title: Simvastatin inhibits osteoclast differentiation by scavenging reactive oxygen species.

Journal: Experimental & molecular medicine 20111130

Title: Arginine or citrulline associated with a statin stimulates nitric oxide production in bovine aortic endothelial cells.

Journal: European journal of pharmacology 20111130

Title: Simvastatin inhibits pro-inflammatory mediators through induction of heme oxygenase-1 expression in lipopolysaccharide-stimulated RAW264.7 macrophages.

Journal: Toxicology letters 20111130

Title: Involvement of Chk1-Cdc25A-cyclin A/CDK2 pathway in simvastatin induced S-phase cell cycle arrest and apoptosis in multiple myeloma cells.

Journal: European journal of pharmacology 20111130

Title: Simvastatin promotes osteogenic differentiation of mouse embryonic stem cells via canonical Wnt/β-catenin signaling.

Journal: Molecules and cells 20111130

Title: Interaction of fluvastatin with the liver-specific Na+ -dependent taurocholate cotransporting polypeptide (NTCP).

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20111120

Title: 12/15-Lipoxygenase gene knockout severely impairs ischemia-induced angiogenesis due to lack of Rac1 farnesylation.

Journal: Blood 20111117

Title: Effects of the CETP inhibitor evacetrapib administered as monotherapy or in combination with statins on HDL and LDL cholesterol: a randomized controlled trial.

Journal: JAMA 20111116

Title: ACP Journal Club. Simvastatin plus ezetimibe reduced major atherosclerotic events in patients with chronic kidney disease.

Journal: Annals of internal medicine 20111115

Title: Sitagliptin and simvastatin (juvisync).

Journal: The Medical letter on drugs and therapeutics 20111114

Title: Novel medications for epilepsy.

Journal: Drugs 20111112

Title: Cost-effectiveness of the use of low- and high-potency statins in people at low cardiovascular risk.

Journal: CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20111108

Title: HMG-CoA reductase inhibitor simvastatin suppresses Toll-like receptor 2 ligand-induced activation of nuclear factor kappa B by preventing RhoA activation in monocytes from rheumatoid arthritis patients.

Journal: Rheumatology international 20111101

Title: Cardiovascular and economic outcomes after initiation of atorvastatin versus simvastatin in an employed population stratified by cardiovascular risk.

Journal: American journal of therapeutics 20111101

Title: Statins augment the chemosensitivity of colorectal cancer cells inducing epigenetic reprogramming and reducing colorectal cancer cell 'stemness' via the bone morphogenetic protein pathway.

Journal: Gut 20111101

Title: The effect of bezafibrate and omega-3 fatty acids on lymphocyte cytokine release and systemic inflammation in patients with isolated hypertriglyceridemia.

Journal: European journal of clinical pharmacology 20111101

Title: Acute simvastatin increases endothelial nitric oxide synthase phosphorylation via AMP-activated protein kinase and reduces contractility of isolated rat mesenteric resistance arteries.

Journal: Clinical science (London, England : 1979) 20111101

Title: Persistent lipid abnormalities in statin-treated patients with diabetes mellitus in Europe and Canada: results of the Dyslipidaemia International Study.

Journal: Diabetic medicine : a journal of the British Diabetic Association 20111101

Title: Bone healing of critical-sized nasal defects in rabbits by statins in two different carriers.

Journal: Clinical oral implants research 20111101

Title: The neuroprotective effect of two statins: simvastatin and pravastatin on a streptozotocin-induced model of Alzheimer's disease in rats.

Journal: Journal of neural transmission (Vienna, Austria : 1996) 20111101

Title: Pathogenesis-based therapy reverses cutaneous abnormalities in an inherited disorder of distal cholesterol metabolism.

Journal: The Journal of investigative dermatology 20111101

Title: Simvastatin upregulates Bcl-2 expression and protects retinal neurons from early ischemia/reperfusion injury in the rat retina.

Journal: Experimental eye research 20111101

Title: IMProving Adherence using Combination Therapy (IMPACT): design and protocol of a randomised controlled trial in primary care.

Journal: Contemporary clinical trials 20111101

Title: Effects of myosin heavy chain (MHC) plasticity induced by HMGCoA-reductase inhibition on skeletal muscle functions.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20111101

Title: Heterologous expression and purification of the soybean 7S globulin α' subunit extension region: in vitro evidence of its involvement in cell cholesterol homeostasis.

Journal: Protein expression and purification 20111101

Title: Photo-cured hyaluronic acid-based hydrogels containing simvastatin as a bone tissue regeneration scaffold.

Journal: Biomaterials 20111101

Title: Effects of simvastatin and metformin on polycystic ovary syndrome after six months of treatment.

Journal: The Journal of clinical endocrinology and metabolism 20111101

Title: Drug interactions with mitotane by induction of CYP3A4 metabolism in the clinical management of adrenocortical carcinoma.

Journal: Clinical endocrinology 20111101

Title: Differential effects of atorvastatin treatment and withdrawal on pentylenetetrazol-induced seizures.

Journal: Epilepsia 20111101

Title: Resveratrol inhibits the mevalonate pathway and potentiates the antiproliferative effects of simvastatin in rat theca-interstitial cells.

Journal: Fertility and sterility 20111101

Title: Modulators of induction of plasminogen activator inhibitor type-1 in HepG2 cells by transforming growth factor-β.

Journal: Coronary artery disease 20111101

Title: Statin effects on regulatory and proinflammatory factors in chronic idiopathic urticaria.

Journal: Clinical and experimental immunology 20111101

Title: Comparison of the effects of simvastatin vs. rosuvastatin vs. simvastatin/ezetimibe on parameters of insulin resistance.

Journal: International journal of clinical practice 20111101

Title: A cost-benefit analysis of lipid standardization in the United States.

Journal: Preventing chronic disease 20111101

Title: Apolipoprotein B100 is a better treatment target than calculated LDL and non-HDL cholesterol in statin-treated patients.

Journal: Annals of clinical biochemistry 20111101

Title: Antimicrobial effect of statins: organic solvents might falsify microbiological testing results.

Journal: International journal of clinical pharmacology and therapeutics 20111101

Title: Statin therapy attenuates growth and malignant potential of human esophageal adenocarcinoma cells.

Journal: The Journal of thoracic and cardiovascular surgery 20111101

Title: Statin therapy for the prevention of atrial fibrillation: a meta-analysis of randomized controlled trials.

Journal: Pharmacotherapy 20111101

Title: Modifiers of symptomatic embolic risk in infective endocarditis.

Journal: Mayo Clinic proceedings 20111101

Title: Effects of Lycium barbarum aqueous and ethanol extracts on high-fat-diet induced oxidative stress in rat liver tissue.

Journal: Molecules (Basel, Switzerland) 20111101

Title: Risk of pneumonia in patients taking statins: population-based nested case-control study.

Journal: The British journal of general practice : the journal of the Royal College of General Practitioners 20111101

Title: [Retinal microangiopathy in arterial hypertension as an early marker of a cerebral macroangiopathy].

Journal: Deutsche medizinische Wochenschrift (1946) 20111101

Title: Fatal prion disease in a mouse model of genetic E200K Creutzfeldt-Jakob disease.

Journal: PLoS pathogens 20111101

Title: Lipid lowering drugs and gallstones: a therapeutic option?

Journal: Current pharmaceutical design 20111101

Title: Discontinuation of unnecessary medications in older adults.

Journal: The Consultant pharmacist : the journal of the American Society of Consultant Pharmacists 20111101

Title: Gender differences, polypharmacy, and potential pharmacological interactions in the elderly.

Journal: Clinics (Sao Paulo, Brazil) 20111101

Title: Simvastatin ameliorates gentamicin-induced renal injury in rats.

Journal: Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia 20111101

Title: The fixed-dose combination drug for secondary cardiovascular prevention project: improving equitable access and adherence to secondary cardiovascular prevention with a fixed-dose combination drug. Study design and objectives.

Journal: American heart journal 20111101

Title: Relative burden of large CNVs on a range of neurodevelopmental phenotypes.

Journal: PLoS genetics 20111101

Title: Intermittent supplementation with rapamycin as a dietary restriction mimetic.

Journal: Aging 20111101

Title: HDL-C: role as a risk modifier.

Journal: Atherosclerosis. Supplements 20111101

Title: Pitavastatin: novel effects on lipid parameters.

Journal: Atherosclerosis. Supplements 20111101

Title: Pitavastatin: clinical effects from the LIVES Study.

Journal: Atherosclerosis. Supplements 20111101

Title: Hormesis does not make sense except in the light of TOR-driven aging.

Journal: Aging 20111101

Title: The effects of statin and niacin on plaque stability, plaque regression, inflammation and oxidative stress in patients with mild to moderate coronary artery stenosis.

Journal: Korean circulation journal 20111101

Title: Predictors of echocardiographic progression in patients with mild aortic stenosis.

Journal: Korean circulation journal 20111101

Title: Slow Coronary Flow is Related to Increased Carotid Intima-Media Thickness but Not Pulse Wave Velocity.

Journal: Korean circulation journal 20111101

Title: Prior use of 3-hydroxy-3-methyl-glutaryl-coenzyme a reductase inhibitor, simvastatin fails to improve outcome after experimental intracerebral hemorrhage.

Journal: Journal of Korean Neurosurgical Society 20111101

Title: Efficient discovery of anti-inflammatory small-molecule combinations using evolutionary computing.

Journal: Nature chemical biology 20111023

Title: Benefits of lowering cholesterol in chronic kidney disease.

Journal: Lancet (London, England) 20111015

Title: Benefits of lowering cholesterol in chronic kidney disease.

Journal: Lancet (London, England) 20111015

Title: Benefits of lowering cholesterol in chronic kidney disease.

Journal: Lancet (London, England) 20111015

Title: Benefits of lowering cholesterol in chronic kidney disease.

Journal: Lancet (London, England) 20111015

Title: Statin prescriptions and breast cancer recurrence risk: a Danish nationwide prospective cohort study.

Journal: Journal of the National Cancer Institute 20111005

Title: Statins for women with polycystic ovary syndrome not actively trying to conceive.

Journal: The Cochrane database of systematic reviews 20111005

Title: Effect of moderate and high-dose simvastatin on asymmetric dimethylarginine-homocysteine metabolic pathways in patients with newly detected severe hypercholesterolemia.

Journal: Cardiovascular therapeutics 20111001

Title: Apoptotic induction by simvastatin in human lung cancer A549 cells via Akt signaling dependent down-regulation of survivin.

Journal: Investigational new drugs 20111001

Title: Simvastatin enhances irinotecan-induced apoptosis in human non-small cell lung cancer cells by inhibition of proteasome activity.

Journal: Investigational new drugs 20111001

Title: Enhanced dissolution rate of simvastatin using spherical crystallization technique.

Journal: Pharmaceutical development and technology 20111001

Title: Protein prenylation contributes to the effects of LPS on EFS-induced responses in human isolated bronchi.

Journal: American journal of respiratory cell and molecular biology 20111001

Title: NOX1, 2, 4, 5: counting out oxidative stress.

Journal: British journal of pharmacology 20111001

Title: Increased expression of Foxj1 after traumatic brain injury.

Journal: Journal of molecular neuroscience : MN 20111001

Title: Cholesterol-lowering strategies reduce vascular LRP1 overexpression induced by hypercholesterolaemia.

Journal: European journal of clinical investigation 20111001

Title: Highly efficient release of lovastatin from poly(lactic-co-glycolic acid) nanoparticles enhances bone repair in rats.

Journal: Journal of orthopaedic research : official publication of the Orthopaedic Research Society 20111001

Title: Non-phosphorylated FTY720 induces apoptosis of human microglia by activating SREBP2.

Journal: Cellular and molecular neurobiology 20111001

Title: Hip circumference is associated with high density lipoprotein cholesterol response following statin therapy in hypertensive subjects.

Journal: Journal of endocrinological investigation 20111001

Title: Successful treatment of xanthoma disseminatum with simvastatin.

Journal: The Journal of dermatology 20111001

Title: Simvastatin in traumatic brain injury: effect on brain edema mechanisms.

Journal: Critical care medicine 20111001

Title: Pilot trial of simvastatin in the treatment of sporadic inclusion-body myositis.

Journal: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20111001

Title: Thalidomide, dexamethasone and lovastatin with autologous stem cell transplantation as a salvage immunomodulatory therapy in patients with relapsed and refractory multiple myeloma.

Journal: Annals of hematology 20111001

Title: Endotoxin-induced cardiovascular dysfunction in mice: effect of simvastatin.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20111001

Title: Erectile response to type 5 phosphodiesterase inhibitor could be preserved with the addition of simvastatin to conventional insulin treatment in rat model of diabetes.

Journal: International journal of andrology 20111001

Title: Statins inhibit chemotactic interaction between CCL20 and CCR6 in vitro: possible relevance to psoriasis treatment.

Journal: Experimental dermatology 20111001

Title: Genetic testing for early detection of individuals at risk of coronary heart disease and monitoring response to therapy: challenges and promises.

Journal: Current atherosclerosis reports 20111001

Title: Left atrial systolic force in asymptomatic aortic stenosis.

Journal: Echocardiography (Mount Kisco, N.Y.) 20111001

Title: Lipid-altering efficacy of switching to ezetimibe/simvastatin 10/20 mg versus rosuvastatin 10 mg in high-risk patients with and without metabolic syndrome.

Journal: Diabetes & vascular disease research 20111001

Title: Simvastatin protects against the development of monocrotaline-induced pulmonary hypertension in rats via a heme oxygenase-1-dependent pathway.

Journal: Experimental lung research 20111001

Title: Fenofibrate: a review of its use in dyslipidaemia.

Journal: Drugs 20111001

Title: The value of atorvastatin over the product life cycle in the United States.

Journal: Clinical therapeutics 20111001

Title: A comparative study of antioxidant vitamins and simvastatin in hypercholesterolimic rabbits.

Journal: Pakistan journal of pharmaceutical sciences 20111001

Title: Species-dependent sensitivity to contaminants: an approach using primary hepatocyte cultures with three marine fish species.

Journal: Marine environmental research 20111001

Title: Fluvastatin enhances sorafenib cytotoxicity in melanoma cells via modulation of AKT and JNK signaling pathways.

Journal: Anticancer research 20111001

Title: Current status of statin therapy for stroke prevention.

Journal: Expert review of cardiovascular therapy 20111001

Title: Adverse drug reactions caused by drug-drug interactions reported to Croatian Agency for Medicinal Products and Medical Devices: a retrospective observational study.

Journal: Croatian medical journal 20111001

Title: Simvastatin-induced cardiac autonomic control improvement in fructose-fed female rats.

Journal: Clinics (Sao Paulo, Brazil) 20111001

Title: [Rosuvastatin improves myocardial function and arteriosclerosis plaque in patients with ST-segment elevation after acute myocardial infarction and percutaneous coronary intervention].

Journal: Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20111001

Title: [Rhabdomyolysis related to statin and seizures: report of 3 cases].

Journal: Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20111001

Title: Avascular necrosis of the knees and ulcerative colitis.

Journal: Revista espanola de enfermedades digestivas : organo oficial de la Sociedad Espanola de Patologia Digestiva 20111001

Title: Study on the hypochlolesterolemic and antioxidative effects of tyramine derivatives from the root bark of Lycium chenese Miller.

Journal: Nutrition research and practice 20111001

Title: On call. My doctor just started me on Zocor to lower my cholesterol. I have had just one side effect, forgetfulness. It's not as bad as it sounds, since my memory remains excellent, except that I often forget to take my pill in the evening. So I'd like to know if it would be okay for me to take Zocor in the morning with my other pills, which I never forget.

Journal: Harvard men's health watch 20111001

Title: Inappropriate concomitant use of amlodipine and simvastatin: A report on its incidence in a primary care unit.

Journal: Indian journal of endocrinology and metabolism 20111001

Title: Are patients undergoing treatment of hyperlipidaemia with statins the best candidates for early cardiac rehabilitation?

Journal: Archives of medical science : AMS 20111001

Title: An attempt to make lipid-lowering therapy more effective in Hungary. The results of MULTI GAP 2010 and the PLUS Program.

Journal: Archives of medical science : AMS 20111001

Title: Effectiveness and tolerability of ezetimibe co-administered with statins versus statin dose-doubling in high-risk patients with persistent hyperlipidemia: The EZE(STAT)2 trial.

Journal: Archives of medical science : AMS 20111001

Title: Safety and impact on cardiovascular events of long-term multifactorial treatment in patients with metabolic syndrome and abnormal liver function tests: a post hoc analysis of the randomised ATTEMPT study.

Journal: Archives of medical science : AMS 20111001

Title: Persistent ductus arteriosus in a 72-year-old woman with paroxysmal atrial fibrillation and depression syndrome: a therapeutic and diagnostic problem.

Journal: Archives of medical science : AMS 20111001

Title: I am a 60-year-old woman with CAD. My LDL is 64 and my HDL is 72 on Zocor, but my doctor thinks Crestor may be better for me. He says it is more potent and could reduce my numbers even more. I would have to pay for this drug out-of-pocket. Do you think the additional cost would be worth it?

Journal: Heart advisor 20111001

Title: Letter by Dumesnil and Pibarot regarding article, 'Outcome of patients with low-gradient 'severe' aortic stenosis and preserved ejection fraction'.

Journal: Circulation 20110927

Title: Letter by Daneshvar regarding article, 'Outcome of patients with low-gradient 'severe' aortic stenosis and preserved ejection fraction'.

Journal: Circulation 20110927

Title: Evaluation of the osteoconductivity of α-tricalcium phosphate, β-tricalcium phosphate, and hydroxyapatite combined with or without simvastatin in rat calvarial defect.

Journal: Journal of biomedical materials research. Part A 20110915

Title: Thiazole- and imidazole-containing peptidomimetic inhibitors of protein farnesyltransferase.

Journal: Bioorganic & medicinal chemistry letters 20110915

Title: Simvastatin inhibits IFN regulatory factor 4 expression and Th17 cell differentiation in CD4+ T cells derived from patients with multiple sclerosis.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20110915

Title: Donor simvastatin treatment abolishes rat cardiac allograft ischemia/reperfusion injury and chronic rejection through microvascular protection.

Journal: Circulation 20110906

Title: Antioxidants prevent the RhoA inhibition evoked by crocidolite asbestos in human mesothelial and mesothelioma cells.

Journal: American journal of respiratory cell and molecular biology 20110901

Title: Simvastatin is protective during Staphylococcus aureus pneumonia.

Journal: Current pharmaceutical biotechnology 20110901

Title: A population pharmacokinetic-pharmacodynamic model for simvastatin that predicts low-density lipoprotein-cholesterol reduction in patients with primary hyperlipidaemia.

Journal: Basic & clinical pharmacology & toxicology 20110901

Title: Meal-induced increases in C-reactive protein, interleukin-6 and tumour necrosis factor α are attenuated by prandial + basal insulin in patients with Type 2 diabetes.

Journal: Diabetic medicine : a journal of the British Diabetic Association 20110901

Title: Impact of HMG-CoA reductase inhibition on oxidant-induced injury in human retinal pigment epithelium cells.

Journal: Journal of cellular biochemistry 20110901

Title: The effect of ezetimibe on peripheral arterial atherosclerosis depends upon statin use at baseline.

Journal: Atherosclerosis 20110901

Title: Chronic obstructive pulmonary disease: patho-physiology, current methods of treatment and the potential for simvastatin in disease management.

Journal: Expert opinion on drug delivery 20110901

Title: AAPS workshop report: strategies to address therapeutic protein-drug interactions during clinical development.

Journal: The AAPS journal 20110901

Title: Physiologically based pharmacokinetic modeling of intestinal first-pass metabolism of CYP3A substrates with high intestinal extraction.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20110901

Title: High plasma leptin levels confer increased risk of atherosclerosis in women with systemic lupus erythematosus, and are associated with inflammatory oxidised lipids.

Journal: Annals of the rheumatic diseases 20110901

Title: Monitoring of 7α-hydroxy-4-cholesten-3-one during therapy of cerebrotendinous xanthomatosis: a case report.

Journal: Chemistry and physics of lipids 20110901

Title: Reduction of spinal cord ischemia/reperfusion injury with simvastatin in rats.

Journal: Anesthesia and analgesia 20110901

Title: Simvastatin exerts favourable effects on neointimal formation in a mouse model of vein graft.

Journal: European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery 20110901

Title: Use and efficacy of bone morphogenetic proteins in fracture healing.

Journal: International orthopaedics 20110901

Title: Serum bilirubin levels in familial hypercholesterolemia: a new risk marker for cardiovascular disease?

Journal: Journal of lipid research 20110901

Title: Optimal pharmacotherapy to combat the atherogenic lipid triad.

Journal: Current opinion in cardiology 20110901

Title: Phaleria macrocarpa (Scheff.) Boerl fruit aqueous extract enhances LDL receptor and PCSK9 expression in vivo and in vitro.

Journal: Journal of ethnopharmacology 20110901

Title: Acrolein-induced dyslipidemia and acute-phase response are independent of HMG-CoA reductase.

Journal: Molecular nutrition & food research 20110901

Title: Combination therapy for dyslipidemia.

Journal: Current opinion in cardiology 20110901

Title: A copy number variation morbidity map of developmental delay.

Journal: Nature genetics 20110901

Title: Probucol attenuates inflammation and increases stability of vulnerable atherosclerotic plaques in rabbits.

Journal: The Tohoku journal of experimental medicine 20110901

Title: Mechanically induced experimental knee osteoarthritis benefits from anti-inflammatory and immunomodulatory properties of simvastatin via inhibition of matrix metalloproteinase-3.

Journal: Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology 20110901

Title: Evaluation of a pharmacist-managed amiodarone monitoring program.

Journal: Journal of managed care pharmacy : JMCP 20110901

Title: Effect of chronic kidney disease on warfarin management in a pharmacist-managed anticoagulation clinic.

Journal: Journal of managed care pharmacy : JMCP 20110901

Title: Long-term efficacy of pitavastatin versus simvastatin.

Journal: Advances in therapy 20110901

Title: Comparative efficacy of pitavastatin and simvastatin in high-risk patients: a randomized controlled trial.

Journal: Advances in therapy 20110901

Title: Simvastatin dosing restrictions; monitoring amiodarone therapy.

Journal: JAAPA : official journal of the American Academy of Physician Assistants 20110901

Title: Allopurinol reduces the lethality associated with acute renal failure induced by Crotalus durissus terrificus snake venom: comparison with probenecid.

Journal: PLoS neglected tropical diseases 20110901

Title: Outpatient drug oversupply at a teaching hospital in Thailand.

Journal: Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20110901

Title: Comparison of clinical outcomes of hydrophilic and lipophilic statins in patients with acute myocardial infarction.

Journal: The Korean journal of internal medicine 20110901

Title: Molecular imaging of high-risk atherosclerotic plaques: is it clinically translatable?

Journal: Korean circulation journal 20110901

Title: Changes of pulmonary pathology and gene expressions after simvastatin treatment in the monocrotaline-induced pulmonary hypertension rat model.

Journal: Korean circulation journal 20110901

Title: [Say no to the extremes in the debate on lipid reduction].

Journal: Lakartidningen 20110901

Title: [Current evidence about lipid-lowering therapy and coronary plaque].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20110901

Title: Nanostructured lipid carrier versus solid lipid nanoparticles of simvastatin: comparative analysis of characteristics, pharmacokinetics and tissue uptake.

Journal: International journal of pharmaceutics 20110830

Title: Low-density lipoprotein lowering does not improve calf muscle perfusion, energetics, or exercise performance in peripheral arterial disease.

Journal: Journal of the American College of Cardiology 20110830

Title: Learning to walk before we run: the mechanics of medical intervention for peripheral arterial disease.

Journal: Journal of the American College of Cardiology 20110830

Title: Effect of the traditional Chinese medicine tongxinluo on endothelial dysfunction rats studied by using urinary metabonomics based on liquid chromatography-mass spectrometry.

Journal: Journal of pharmaceutical and biomedical analysis 20110825

Title: New simvastatin dosing recommendations.

Journal: The Medical letter on drugs and therapeutics 20110825

Title: Re: Effect of simvastatin on cetuximab resistance in human colorectal cancer with KRAS mutations.

Journal: Journal of the National Cancer Institute 20110817

Title: Differences in cardiovascular risk profile between electrocardiographic hypertrophy versus strain in asymptomatic patients with aortic stenosis (from SEAS data).

Journal: The American journal of cardiology 20110815

Title: Simvastatin induces apoptosis by a Rho-dependent mechanism in cultured cardiac fibroblasts and myofibroblasts.

Journal: Toxicology and applied pharmacology 20110815

Title: Cardiovascular MRI in clinical trials: expanded applications through novel surrogate endpoints.

Journal: Heart (British Cardiac Society) 20110815

Title: Novel benzoxazine and benzothiazine derivatives as multifunctional antihyperlipidemic agents.

Journal: Journal of medicinal chemistry 20110811

Title: Statins for acute ischemic stroke.

Journal: The Cochrane database of systematic reviews 20110810

Title: A randomized, double-blind, placebo-controlled trial of simvastatin to treat Alzheimer disease.

Journal: Neurology 20110809

Title: Intronic polymorphism in CYP3A4 affects hepatic expression and response to statin drugs.

Journal: The pharmacogenomics journal 20110801

Title: Effects of simvastatin on proinflammatory cytokines and matrix metalloproteinases in hypercholesterolemic individuals.

Journal: Inflammation 20110801

Title: The effects of simvastatin on angiogenesis: studied by an original model of atherosclerosis and acute myocardial infarction in rabbit.

Journal: Molecular biology reports 20110801

Title: Early alveolar bone regeneration in rats after topical administration of simvastatin.

Journal: Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 20110801

Title: Simvastatin improves learning and memory in control but not in olfactory bulbectomized rats.

Journal: Psychopharmacology 20110801

Title: Simvastatin alters fibroblastic cell responses involved in tissue repair.

Journal: Journal of periodontal research 20110801

Title: Long-term simvastatin attenuates lung injury and oxidative stress in murine acute lung injury models induced by oleic Acid and endotoxin.

Journal: Respiratory care 20110801

Title: Role of prostaglandin pathway and alendronate-based carriers to enhance statin-induced bone.

Journal: Molecular pharmaceutics 20110801

Title: Statins regulate interleukin-1β-induced RANKL and osteoprotegerin production by human gingival fibroblasts.

Journal: Journal of periodontal research 20110801

Title: Simvastatin has beneficial effect on pulmonary artery hypertension by inhibiting NF-κB expression.

Journal: Molecular and cellular biochemistry 20110801

Title: Simvastatin enhances aquaporin-2 surface expression and urinary concentration in vasopressin-deficient Brattleboro rats through modulation of Rho GTPase.

Journal: American journal of physiology. Renal physiology 20110801

Title: Hyperlipidaemia and cardiovascular disease: do fibrates have a role?

Journal: Current opinion in lipidology 20110801

Title: Simvastatin effects on androgens, inflammatory mediators, and endogenous pituitary gonadotropins among patients with PCOS undergoing IVF: results from a prospective, randomized, placebo-controlled clinical trial.

Journal: Journal of investigative medicine : the official publication of the American Federation for Clinical Research 20110801

Title: Ezetimibe combined with simvastatin compared with simvastatin alone results in a greater suppression of oxidative stress and enhanced fibrinolysis in patients after acute coronary events.

Journal: Journal of cardiovascular pharmacology 20110801

Title: Parkinson's disease mouse models in translational research.

Journal: Mammalian genome : official journal of the International Mammalian Genome Society 20110801

Title: Statins affect AQP2 traffic.

Journal: American journal of physiology. Renal physiology 20110801

Title: Disturbed subjective sleep characteristics in adult patients with long-standing type 1 diabetes mellitus.

Journal: Diabetologia 20110801

Title: The pharmacological inhibition of sterol biosynthesis in Leishmania is counteracted by enhancement of LDL endocytosis.

Journal: Acta tropica 20110801

Title: Inhibition of pathological differentiation of valvular interstitial cells by C-type natriuretic peptide.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20110801

Title: Intestinal microbiota in human health and disease: the impact of probiotics.

Journal: Genes & nutrition 20110801

Title: The ezetimibe controversy: implications for clinical practice.

Journal: Therapeutic advances in cardiovascular disease 20110801

Title: Fenofibrate: a review of its lipid-modifying effects in dyslipidemia and its vascular effects in type 2 diabetes mellitus.

Journal: American journal of cardiovascular drugs : drugs, devices, and other interventions 20110801

Title: A single bisphosphonate infusion does not accelerate fracture healing in high tibial osteotomies.

Journal: Acta orthopaedica 20110801

Title: Begin with the real-world patients of non-goal-achieved hypercholesterolemia in taiwan through the ezetimibe/simvastatin tablet - The BRAVO Study.

Journal: Current medical research and opinion 20110801

Title: Reversal of drug-induced rhabdomyolysis on bone scan.

Journal: Clinical nuclear medicine 20110801

Title: Geraniol and simvastatin show a synergistic effect on a human hepatocarcinoma cell line.

Journal: Cell biochemistry and function 20110801

Title: Fenofibrate plus simvastatin (fixed-dose combination) for the treatment of dyslipidaemia.

Journal: Expert opinion on pharmacotherapy 20110801

Title: Statins promote the growth of experimentally induced cerebral aneurysms in estrogen-deficient rats.

Journal: Stroke 20110801

Title: Simvastatin as add-on therapy to interferon β-1a for relapsing-remitting multiple sclerosis (SIMCOMBIN study): a placebo-controlled randomised phase 4 trial.

Journal: The Lancet. Neurology 20110801

Title: Combining statins with interferon β in multiple sclerosis: think twice, it might not be all right.

Journal: The Lancet. Neurology 20110801

Title: Therapy and clinical trials: aggressive statin therapy versus combined and emerging approaches.

Journal: Current opinion in lipidology 20110801

Title: HMG-CoA reductase inhibitors enhance phagocytosis by upregulating ATP-binding cassette transporter A7.

Journal: Atherosclerosis 20110801

Title: Acquired port-wine stain occurring in association with a congenital lesion.

Journal: Clinical and experimental dermatology 20110801

Title: Pitavastatin calcium: clinical review of a new antihyperlipidemic medication.

Journal: Clinical therapeutics 20110801

Title: Polyamines in aging and disease.

Journal: Aging 20110801

Title: Retrospective study on antihyperlipidemic efficacy and safety of simvastatin, ezetimibe and their combination in Korean adults.

Journal: Archives of pharmacal research 20110801

Title: Effect of previous statin therapy in patients with acute coronary syndrome and percutaneous coronary intervention.

Journal: Korean circulation journal 20110801

Title: Trial clouds use of niacin with a statin.

Journal: Harvard heart letter : from Harvard Medical School 20110801

Title: Weighing the benefits of high-dose simvastatin against the risk of myopathy.

Journal: The New England journal of medicine 20110728

Title: Comparison of different extraction methods for the determination of statin drugs in wastewater and river water by HPLC/Q-TOF-MS.

Journal: Talanta 20110715

Title: [Effects of simvastatin plus all-trans retinoic acid on WT1/hDMP1 gene expression profiles of human promyelocytic leukemia cell line NB4].

Journal: Zhonghua yi xue za zhi 20110712

Title: Effect of early intensive multifactorial therapy on 5-year cardiovascular outcomes in individuals with type 2 diabetes detected by screening (ADDITION-Europe): a cluster-randomised trial.

Journal: Lancet (London, England) 20110709

Title: Simvastatin induces estrogen receptor-alpha expression in bone, restores bone loss, and decreases ERα expression and uterine wet weight in ovariectomized rats.

Journal: Journal of bone and mineral metabolism 20110701

Title: Lipid-altering efficacy and safety profile of combination therapy with ezetimibe/statin vs. statin monotherapy in patients with and without diabetes: an analysis of pooled data from 27 clinical trials.

Journal: Diabetes, obesity & metabolism 20110701

Title: Use of Entero-Test, a simple approach for non-invasive clinical evaluation of the biliary disposition of drugs.

Journal: British journal of clinical pharmacology 20110701

Title: Medical management of diabetic retinopathy: fenofibrate and ACCORD Eye studies.

Journal: Eye (London, England) 20110701

Title: Simulation of clinical drug-drug interactions from hepatocyte CYP3A4 induction data and its potential utility in trial designs.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20110701

Title: Use of transporter knockdown Caco-2 cells to investigate the in vitro efflux of statin drugs.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20110701

Title: Effect of doublecortin on self-renewal and differentiation in brain tumor stem cells.

Journal: Cancer science 20110701

Title: Pulmonary arterial hypertension and statins: an update.

Journal: Current opinion in cardiology 20110701

Title: Ezetimibe beneficially influences fasting and postprandial triglyceride-rich lipoproteins in type 2 diabetes.

Journal: Atherosclerosis 20110701

Title: Comparisons of apolipoprotein B levels estimated by immunoassay, nuclear magnetic resonance, vertical auto profile, and non-high-density lipoprotein cholesterol in subjects with hypertriglyceridemia (SAFARI Trial).

Journal: The American journal of cardiology 20110701

Title: Pharmacogenomics and adverse drug reactions: the case of statins.

Journal: Expert opinion on pharmacotherapy 20110701

Title: Osteogenic induction of bone marrow-derived stromal cells on simvastatin-releasing, biodegradable, nano- to microscale fiber scaffolds.

Journal: Annals of biomedical engineering 20110701

Title: Statins, vitamin D, and neuropathic pain.

Journal: Pain 20110701

Title: Topical anti-inflammatory effect of hypocholesterolaemic drugs.

Journal: The Journal of pharmacy and pharmacology 20110701

Title: Comparison of effects of morning versus evening administration of ezetimibe/simvastatin on serum cholesterol in patients with primary hypercholesterolemia.

Journal: The Annals of pharmacotherapy 20110701

Title: Stroke management.

Journal: Annals of Indian Academy of Neurology 20110701

Title: Optimizing secondary prevention: Statin prescribing across East and West London in accordance with NICE guidelines.

Journal: JRSM short reports 20110701

Title: Randomized clinical trial of aspirin and simvastatin for pulmonary arterial hypertension: ASA-STAT.

Journal: Circulation 20110628

Title: Future of clinical trials for pulmonary hypertension.

Journal: Circulation 20110628

Title: Dynamic CpG island methylation landscape in oocytes and preimplantation embryos.

Journal: Nature genetics 20110626

Title: [Pharmaco-economic optimization of cholesterol-lowering treatment with statins].

Journal: Medicina clinica 20110625

Title: SHARP: a stab in the right direction in chronic kidney disease.

Journal: Lancet (London, England) 20110625

Title: Progesterone impairs human ether-a-go-go-related gene (HERG) trafficking by disruption of intracellular cholesterol homeostasis.

Journal: The Journal of biological chemistry 20110624

Title: Simvastatin induces heme oxygenase-1 expression but fails to reduce inflammation in the capsule surrounding a silicone shell implant in rats.

Journal: The Journal of surgical research 20110615

Title: Effect of statins on cholesterol crystallization and atherosclerotic plaque stabilization.

Journal: The American journal of cardiology 20110615

Title: Statins for acute coronary syndrome.

Journal: The Cochrane database of systematic reviews 20110615

Title: Effect of the amyloidogenic L75P apolipoprotein A-I variant on HDL subpopulations.

Journal: Clinica chimica acta; international journal of clinical chemistry 20110611

Title: The effects of lowering LDL cholesterol with simvastatin plus ezetimibe in patients with chronic kidney disease (Study of Heart and Renal Protection): a randomised placebo-controlled trial.

Journal: Lancet (London, England) 20110609

Title: Statins and prostate cancer diagnosis and grade in a veterans population.

Journal: Journal of the National Cancer Institute 20110608

Title: Single coronary artery from the right sinus of Valsalva.

Journal: Heart international 20110602

Title: Combination of simvastatin and imatinib sensitizes the CD34+ cells in K562 to cell death.

Journal: Medical oncology (Northwood, London, England) 20110601

Title: Reimbursement of pharmaceuticals: reference pricing versus health technology assessment.

Journal: The European journal of health economics : HEPAC : health economics in prevention and care 20110601

Title: Haemostatic effects of simvastatin in subjects with impaired glucose tolerance.

Journal: Internal medicine journal 20110601

Title: High-density lipoprotein (HDL) cholesterol: leveraging practice-based biobank cohorts to characterize clinical and genetic predictors of treatment outcome.

Journal: The pharmacogenomics journal 20110601

Title: Simvastatin and other HMG-CoA reductase inhibitors on brain cholesterol levels in Alzheimer's disease.

Journal: Current Alzheimer research 20110601

Title: Regression and stabilization of advanced murine atherosclerotic lesions: a comparison of LDL lowering and HDL raising gene transfer strategies.

Journal: Journal of molecular medicine (Berlin, Germany) 20110601

Title: Prospects of statins in Parkinson disease.

Journal: The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry 20110601

Title: Differential effects on inhibition of cholesterol absorption by plant stanol and plant sterol esters in apoE-/- mice.

Journal: Cardiovascular research 20110601

Title: The influence of genetic polymorphisms and interacting drugs on initial response to warfarin in Chinese patients with heart valve replacement.

Journal: European journal of clinical pharmacology 20110601

Title: PPARα mediates the anti-inflammatory effect of simvastatin in an experimental model of zymosan-induced multiple organ failure.

Journal: British journal of pharmacology 20110601

Title: Switching from statin monotherapy to ezetimibe/simvastatin or rosuvastatin modifies the relationships between apolipoprotein B, LDL cholesterol, and non-HDL cholesterol in patients at high risk of coronary disease.

Journal: Clinical biochemistry 20110601

Title: Role of phospholipid transfer protein in high-density lipoprotein- mediated reverse cholesterol transport.

Journal: Current atherosclerosis reports 20110601

Title: Primary prevention of diastolic dysfunction in the normal heart: the 'eyes wide shut' on a statin pleiotropic effect?

Journal: Atherosclerosis 20110601

Title: Membrane cholesterol modulates cochlear electromechanics.

Journal: Pflugers Archiv : European journal of physiology 20110601

Title: Hypolipidaemic and hypoglycaemic effects of total flavonoids from seed residues of Hippophae rhamnoides L. in mice fed a high-fat diet.

Journal: Journal of the science of food and agriculture 20110601

Title: Validation of human ApoB and ApoAI immunoturbidity assays for non-human primate dyslipidemia and atherosclerosis research.

Journal: Journal of cardiovascular translational research 20110601

Title: Simvastatin preserves diastolic function in experimental hypercholesterolemia independently of its lipid lowering effect.

Journal: Atherosclerosis 20110601

Title: The effects of simvastatin treatment on plasma lipid-related biomarkers in men with dyslipidaemia.

Journal: Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 20110601

Title: Scintigraphic diagnosis of Erdheim-Chester disease.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110601

Title: Combination therapy with statin and fibrate in patients with dyslipidemia associated with insulin resistance, metabolic syndrome and type 2 diabetes mellitus.

Journal: Expert opinion on pharmacotherapy 20110601

Title: Split-liver procedure and inflammatory response: improvement by pharmacological preconditioning.

Journal: The Journal of surgical research 20110601

Title: Simvastatin regulates CXC chemokine formation in streptococcal M1 protein-induced neutrophil infiltration in the lung.

Journal: American journal of physiology. Lung cellular and molecular physiology 20110601

Title: Effects of statins on matrix metalloproteinases and their endogenous inhibitors in human endothelial cells.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20110601

Title: Comparative efficacy of the addition of ezetimibe to statin vs statin titration in patients with hypercholesterolaemia: systematic review and meta-analysis.

Journal: Current medical research and opinion 20110601

Title: Statins, blood pressure and the regression to the mean.

Journal: Nutrition, metabolism, and cardiovascular diseases : NMCD 20110601

Title: A pilot study of the short-term use of simvastatin in sickle cell disease: effects on markers of vascular dysfunction.

Journal: British journal of haematology 20110601

Title: Decline in low-density lipoprotein cholesterol concentration: lipid-lowering drugs, diet, or physical activity? Evidence from the Whitehall II study.

Journal: Heart (British Cardiac Society) 20110601

Title: Double oxidation of the cyclic nonaketide dihydromonacolin L to monacolin J by a single cytochrome P450 monooxygenase, LovA.

Journal: Journal of the American Chemical Society 20110601

Title: Triglyceride-rich lipoproteins and high-density lipoprotein cholesterol in patients at high risk of cardiovascular disease: evidence and guidance for management.

Journal: European heart journal 20110601

Title: Simvastatin-induced myopathy, the role of interaction with diltiazem and genetic predisposition.

Journal: Journal of clinical pharmacy and therapeutics 20110601

Title: Efficacy and safety of long-term ezetimibe/simvastatin treatment in patients with familial hypercholesterolemia.

Journal: International angiology : a journal of the International Union of Angiology 20110601

Title: Niacin extended-release therapy in phase III clinical trials is associated with relatively low rates of drug discontinuation due to flushing and treatment-related adverse events: a pooled analysis.

Journal: American journal of cardiovascular drugs : drugs, devices, and other interventions 20110601

Title: Beneficial effects of cordycepin on metabolic profiles of liver and plasma from hyperlipidemic hamsters.

Journal: Journal of Asian natural products research 20110601

Title: European countries with small populations can obtain low prices for drugs: Lithuania as a case history.

Journal: Expert review of pharmacoeconomics & outcomes research 20110601

Title: Effects of D-003 (10 mg/day) on bone mineral density of the lumbar spine and femoral neck in postmenopausal women: a randomized, double-blinded study.

Journal: The Korean journal of internal medicine 20110601

Title: [Effects of simvastatin on proliferation and apoptosis of acute monocytic leukemia cell line SHI-1].

Journal: Zhongguo shi yan xue ye xue za zhi 20110601

Title: Half-dose ezetimibe add-on to statin therapy is effective in improving resistant hyperlipidaemia in Asian patients with ischaemic heart disease.

Journal: Singapore medical journal 20110601

Title: [Effects of simvastatin on pulmonary nuclear factor-κB and intercellular adhesion molecule-1 in rats with lung injury induced by ischemia-reperfusion of the hind limbs].

Journal: Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20110601

Title: Lipid lowering therapy in type 2 diabetes.

Journal: Wiener medizinische Wochenschrift (1946) 20110601

Title: [Target levels for LDL cholesterol are put out of the running. Cholesterol should be lowered maximally in high cardiovascular risk].

Journal: Lakartidningen 20110601

Title: No deleterious effect of low dose methotrexate on titanium implant osseointegration in a rabbit model.

Journal: Clinics (Sao Paulo, Brazil) 20110601

Title: Clinical Characteristics of Microscopic Colitis in Korea: Prospective Multicenter Study by KASID.

Journal: Gut and liver 20110601

Title: [Effect of modified zhenzhu tiaozhi capsule on lipid peroxidation and endothelial functions in atherosclerotic rabbits].

Journal: Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20110601

Title: Hyponatremia associated with bupropion.

Journal: Electrolyte & blood pressure : E & BP 20110601

Title: Genetic variation in the association of air pollutants with a biomarker of vascular injury in children and adolescents in Isfahan, Iran.

Journal: Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences 20110601

Title: Therapeutic effects of biguanide vs. statin in polycystic ovary syndrome: a randomized clinical trial.

Journal: Pakistan journal of biological sciences : PJBS 20110601

Title: Plasma asymmetric dimethylarginine predicts restenosis after coronary angioplasty.

Journal: Archives of medical science : AMS 20110601

Title: The influence of high-dose simvastatin and diltiazem on myocardium in rabbits: a haemodynamic study.

Journal: Archives of medical science : AMS 20110601

Title: Inclusion of the poorly water-soluble drug simvastatin in mesocellular foam nanoparticles: drug loading and release properties.

Journal: International journal of pharmaceutics 20110530

Title: No impact of KIF6 genotype on vascular risk and statin response among 18,348 randomized patients in the heart protection study.

Journal: Journal of the American College of Cardiology 20110517

Title: Protective role of simvastatin on lung damage caused by burn and cotton smoke inhalation in rats.

Journal: The Journal of surgical research 20110515

Title: A phase 2 study of irinotecan, cisplatin, and simvastatin for untreated extensive-disease small cell lung cancer.

Journal: Cancer 20110515

Title: More on DSMBs.

Journal: The New England journal of medicine 20110512

Title: Cytotoxic effects of statins and thiazolidinediones on meningioma cells.

Journal: Journal of neuro-oncology 20110501

Title: Simvastatin-loaded porous implant surfaces stimulate preosteoblasts differentiation: an in vitro study.

Journal: Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 20110501

Title: Assessment of potential pharmacokinetic interactions of ezetimibe/simvastatin and extended-release niacin tablets in healthy subjects.

Journal: European journal of clinical pharmacology 20110501

Title: Cytotoxic effect of different statins and thiazolidinediones on malignant glioma cells.

Journal: Cancer chemotherapy and pharmacology 20110501

Title: Oral solid compritol 888 ATO nanosuspension of simvastatin: optimization and biodistribution studies.

Journal: Drug development and industrial pharmacy 20110501

Title: New perspectives for the treatment of pulmonary hypertension.

Journal: British journal of pharmacology 20110501

Title: Acute lipophilicity-dependent effect of intravascular simvastatin in the early phase of focal cerebral ischemia.

Journal: Neuropharmacology 20110501

Title: The size of solid lipid nanoparticles: an interpretation from experimental design.

Journal: Colloids and surfaces. B, Biointerfaces 20110501

Title: Cholesterol regulation of receptor-interacting protein 140 via microRNA-33 in inflammatory cytokine production.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20110501

Title: Angiotensin II-induced vascular endothelial dysfunction through RhoA/Rho kinase/p38 mitogen-activated protein kinase/arginase pathway.

Journal: American journal of physiology. Cell physiology 20110501

Title: Monocarboxylate transporters 1 and 4 are involved in the invasion activity of human lung cancer cells.

Journal: Cancer science 20110501

Title: Induction of angiogenesis and modulation of vascular endothelial growth factor receptor-2 by simvastatin after traumatic brain injury.

Journal: Neurosurgery 20110501

Title: Inhibition of geranylgeranylation mediates sensitivity to CHOP-induced cell death of DLBCL cell lines.

Journal: Experimental cell research 20110501

Title: Simvastatin antagonizes CD40L secretion, CXC chemokine formation, and pulmonary infiltration of neutrophils in abdominal sepsis.

Journal: Journal of leukocyte biology 20110501

Title: Simvastatin stimulates apoptosis in cholangiocarcinoma by inhibition of Rac1 activity.

Journal: Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20110501

Title: Use of an adult rat retinal explant model for screening of potential retinal ganglion cell neuroprotective therapies.

Journal: Investigative ophthalmology & visual science 20110501

Title: Effects of simvastatin on cytokines secretion from mononuclear cells from critically ill patients with acute kidney injury.

Journal: Cytokine 20110501

Title: Timing and dose of statin therapy define its impact on inflammatory and endothelial responses during myocardial infarction.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20110501

Title: Adherence to single-pill combination versus multiple-pill combination lipid-modifying therapy among patients with mixed dyslipidemia in a managed care population.

Journal: Current medical research and opinion 20110501

Title: Statins downregulate K6a promoter activity: a possible therapeutic avenue for pachyonychia congenita.

Journal: The Journal of investigative dermatology 20110501

Title: Statins alleviate experimental nerve injury-induced neuropathic pain.

Journal: Pain 20110501

Title: Disease-drug-drug interaction involving tocilizumab and simvastatin in patients with rheumatoid arthritis.

Journal: Clinical pharmacology and therapeutics 20110501

Title: Evaluating optimal lipid levels in patients with mixed dyslipidemia following short- and long-term treatment with fenofibric acid and statin combination therapy: a post hoc analysis.

Journal: Current medical research and opinion 20110501

Title: The beneficial effects of statin therapy may not apply to all forms of crescentic glomerulonephritis.

Journal: The American journal of pathology 20110501

Title: The ACCORD (Action to Control Cardiovascular Risk in Diabetes) Lipid trial: what we learn from subgroup analyses.

Journal: Diabetes care 20110501

Title: [Effects of Chinese herbal drug-containing serum on oxidative damage and apoptosis of umbilical vein endothelial cells induced by oxidized low-density lipoprotein].

Journal: Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20110501

Title: Correlation between Fc γ R III a and aortic atherosclerotic plaque destabilization in ApoE knockout mice and intervention effects of effective components of chuanxiong rhizome and red peony root.

Journal: Chinese journal of integrative medicine 20110501

Title: Clopidogrel-induced liver failure.

Journal: JRSM short reports 20110501

Title: Embryonic anti-aging niche.

Journal: Aging 20110501

Title: Effects of ezetimibe added to ongoing statin therapy on C-reactive protein levels in hypercholesterolemic patients.

Journal: Korean circulation journal 20110501

Title: C-Reactive protein predicts acute myocardial infarction during high-risk noncardiac and vascular surgery.

Journal: Clinics (Sao Paulo, Brazil) 20110501

Title: Statin therapy blunts inflammatory activation and improves prognosis and left ventricular performance assessed by Tissue Doppler Imaging in subjects with chronic ischemic heart failure: results from the Daunia Heart Failure Registry.

Journal: Clinics (Sao Paulo, Brazil) 20110501

Title: Antihyperlipidaemic effects of Eugenia jambolana fruit in diet induced hyperlipidaemic rats.

Journal: JPMA. The Journal of the Pakistan Medical Association 20110501

Title: Simvastatin improves retinal ganglion cell survival and spatial vision after acute retinal ischemia/reperfusion in mice.

Journal: Investigative ophthalmology & visual science 20110420

Title: Effect of simvastatin on cetuximab resistance in human colorectal cancer with KRAS mutations.

Journal: Journal of the National Cancer Institute 20110420

Title: Effects of Curcuma comosa on the expression of atherosclerosis-related cytokine genes in rabbits fed a high-cholesterol diet.

Journal: Journal of ethnopharmacology 20110412

Title: Predictors of new-onset diabetes in patients treated with atorvastatin: results from 3 large randomized clinical trials.

Journal: Journal of the American College of Cardiology 20110405

Title: Statins potently reduce the cytokine-mediated IL-6 release in SMC/MNC cocultures.

Journal: Journal of cellular and molecular medicine 20110401

Title: Simvastatin inhibits cytokine-stimulated Cyr61 expression in osteoblastic cells: a therapeutic benefit for arthritis.

Journal: Arthritis and rheumatism 20110401

Title: The combination of amlodipine and angiotensin receptor blocker or diuretics in high-risk hypertensive patients: rationale, design and baseline characteristics.

Journal: Journal of human hypertension 20110401

Title: The influence of local administration of simvastatin in calvarial bone healing in rats.

Journal: Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery 20110401

Title: Simvastatin improves epithelial dysfunction and airway hyperresponsiveness: from asymmetric dimethyl-arginine to asthma.

Journal: American journal of respiratory cell and molecular biology 20110401

Title: Vascular recovery promoted by atorvastatin and simvastatin after experimental intracerebral hemorrhage: magnetic resonance imaging and histological study.

Journal: Journal of neurosurgery 20110401

Title: In vitro and in vivo effects of statins on platelet-activating factor and its metabolism.

Journal: Angiology 20110401

Title: Adherence of hospital-based cardiologists to lipid guidelines in patients at high risk for cardiovascular events (2L registry).

Journal: Clinical research in cardiology : official journal of the German Cardiac Society 20110401

Title: Simvastatin application to augment facial jaw bone in a dog model: pilot study.

Journal: Journal of periodontology 20110401

Title: Prediction of phenprocoumon maintenance dose and phenprocoumon plasma concentration by genetic and non-genetic parameters.

Journal: European journal of clinical pharmacology 20110401

Title: Endothelial expression of transcription factor Kruppel-like factor 2 and its vasoprotective target genes in the normal and cirrhotic rat liver.

Journal: Gut 20110401

Title: Design of experiments approach to engineer cell-secreted matrices for directing osteogenic differentiation.

Journal: Annals of biomedical engineering 20110401

Title: Previous statins treatment and risk of post-stroke infections.

Journal: Neurologia (Barcelona, Spain) 20110401

Title: Participation of Mac-1, LFA-1 and VLA-4 integrins in the in vitro adhesion of sickle cell disease neutrophils to endothelial layers, and reversal of adhesion by simvastatin.

Journal: Haematologica 20110401

Title: Lactone form 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors (statins) stimulate the osteoblastic differentiation of mouse periodontal ligament cells via the ERK pathway.

Journal: Journal of periodontal research 20110401

Title: Simvastatin prevents skeletal metastasis of breast cancer by an antagonistic interplay between p53 and CD44.

Journal: The Journal of biological chemistry 20110401

Title: Simvastatin therapy reduces prooxidant-antioxidant balance: results of a placebo-controlled cross-over trial.

Journal: Lipids 20110401

Title: Statins inhibit T-acute lymphoblastic leukemia cell adhesion and migration through Rap1b.

Journal: Journal of leukocyte biology 20110401

Title: Metabolomic anatomy of an animal model revealing homeostatic imbalances in dyslipidaemia.

Journal: Molecular bioSystems 20110401

Title: Effect of simvastatin and fenofibrate on cytokine release and systemic inflammation in type 2 diabetes mellitus with mixed dyslipidemia.

Journal: The American journal of cardiology 20110401

Title: The effect of ezetimibe and simvastatin on monocyte cytokine release in patients with isolated hypercholesterolemia.

Journal: Journal of cardiovascular pharmacology 20110401

Title: Different effects of rosuvastatin and simvastatin on myocardial high-energy phosphate metabolism.

Journal: International journal of cardiology 20110401

Title: Statins utilisation pattern: a retrospective evaluation in a tertiary care hospital in Thailand.

Journal: The International journal of pharmacy practice 20110401

Title: Effects of ezetimibe on atherosclerosis in preclinical models.

Journal: Atherosclerosis 20110401

Title: Statin/ezetimibe combination therapy: emerging evidence.

Journal: Current opinion in lipidology 20110401

Title: Pharmacokinetic interactions between alitretinoin and ketoconazole or simvastatin or ciclosporin A.

Journal: Clinical and experimental dermatology 20110401

Title: LDL cholesterol goals and cardiovascular risk during statin treatment: the IDEAL study.

Journal: European journal of cardiovascular prevention and rehabilitation : official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology 20110401

Title: Effectiveness of drug-eluting stents versus bare-metal stents in large coronary arteries in patients with acute myocardial infarction.

Journal: Journal of Korean medical science 20110401

Title: Caveolin-1 in sarcomas: friend or foe?

Journal: Oncotarget 20110401

Title: Comparing pharmaceutical pricing and reimbursement policies in Croatia to the European Union Member States.

Journal: Croatian medical journal 20110401

Title: Statin therapy is associated with decreased pulmonary vascular pressures in severe COPD.

Journal: COPD 20110401

Title: Achievement of recommended lipid and lipoprotein levels with combined ezetimibe/statin therapy versus statin alone in patients with and without diabetes.

Journal: Diabetes & vascular disease research 20110401

Title: [Correlation between the eicosapentaenoic acid, docosahexaenoic acid and the aggressive behavior in mice].

Journal: Fa yi xue za zhi 20110401

Title: Rosuvastatin and primary cardiovascular prevention. Continue to use pravastatin or simvastatin.

Journal: Prescrire international 20110401

Title: [Generic substitution, replacement and substitution of drugs: contemporary extent].

Journal: Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti 20110401

Title: Demographic determinants of response to statin medications.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20110315

Title: A randomized phase II study of gefitinib plus simvastatin versus gefitinib alone in previously treated patients with advanced non-small cell lung cancer.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20110315

Title: A pilot comprehensive lifestyle intervention program (CLIP)--comparison with qualitative lifestyle advice and simvastatin on cardiovascular risk factors in overweight hypercholesterolaemic individuals.

Journal: Nutrition, metabolism, and cardiovascular diseases : NMCD 20110301

Title: The mevalonate cascade as a target to suppress extracellular matrix synthesis by human airway smooth muscle.

Journal: American journal of respiratory cell and molecular biology 20110301

Title: Simvastatin attenuates radiation-induced murine lung injury and dysregulated lung gene expression.

Journal: American journal of respiratory cell and molecular biology 20110301

Title: Marginal increase of sunitinib exposure by grapefruit juice.

Journal: Cancer chemotherapy and pharmacology 20110301

Title: Simvastatin suppresses expression of angiogenic factors in the retinas of rats with streptozotocin-induced diabetes.

Journal: Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20110301

Title: A randomized clinical trial of hydroxymethylglutaryl- coenzyme a reductase inhibition for acute lung injury (The HARP Study).

Journal: American journal of respiratory and critical care medicine 20110301

Title: Motor learning in children with neurofibromatosis type I.

Journal: Cerebellum (London, England) 20110301

Title: Fibrates and statins in the treatment of diabetic retinopathy.

Journal: Current pharmaceutical biotechnology 20110301

Title: Effects of simvastatin on pulmonary C-fiber sensitivity in rats with monocrotaline-induced pulmonary hypertension.

Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20110301

Title: Simvastatin prevents large blood pressure variability induced aggravation of cardiac hypertrophy in hypertensive rats by inhibiting RhoA/Ras-ERK pathways.

Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20110301

Title: Differential metabolic effects of distinct statins.

Journal: Atherosclerosis 20110301

Title: Simvastatin treatment improves survival in a murine model of burn sepsis: Role of interleukin 6.

Journal: Burns : journal of the International Society for Burn Injuries 20110301

Title: Rationale and design of a phase II clinical trial of aspirin and simvastatin for the treatment of pulmonary arterial hypertension: ASA-STAT.

Journal: Contemporary clinical trials 20110301

Title: Protective effects of statin on cardiac fibrosis and apoptosis in adrenomedullin-knockout mice treated with angiotensin II and high salt loading.

Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20110301

Title: The associations between statin use and prostate cancer screening, prostate size, high-grade prostatic intraepithelial neoplasia (PIN), and prostate cancer.

Journal: Cancer causes & control : CCC 20110301

Title: Constitutive activation of LXR in macrophages regulates metabolic and inflammatory gene expression: identification of ARL7 as a direct target.

Journal: Journal of lipid research 20110301

Title: Simvastatin modulates the adhesion and growth of hepatocellular carcinoma cells via decrease of integrin expression and ROCK.

Journal: International journal of oncology 20110301

Title: Cholesterol esterification and atherogenic index of plasma correlate with lipoprotein size and findings on coronary angiography.

Journal: Journal of lipid research 20110301

Title: Simvastatin represses protein synthesis in the muscle-derived C₂C₁₂ cell line with a concomitant reduction in eukaryotic initiation factor 2B expression.

Journal: American journal of physiology. Endocrinology and metabolism 20110301

Title: Socioeconomic and ethnic differences in use of lipid-lowering drugs after deregulation of simvastatin in the UK: the Whitehall II prospective cohort study.

Journal: Atherosclerosis 20110301

Title: The effect of simvastatin alone versus simvastatin plus ezetimibe on the concentration of small dense low-density lipoprotein cholesterol in subjects with primary hypercholesterolemia.

Journal: Current medical research and opinion 20110301

Title: Ezetimibe and low density lipoprotein subfractions: an ongoing debate.

Journal: Current medical research and opinion 20110301

Title: Lipid modification in the elderly using the combination of a statin and a cholesterol absorption inhibitor.

Journal: Expert opinion on pharmacotherapy 20110301

Title: A simplified and high-throughput chromogenic assay for testing tissue factor-dependent procoagulant activity.

Journal: Journal of biomolecular screening 20110301

Title: Outcome of patients with low-gradient 'severe' aortic stenosis and preserved ejection fraction.

Journal: Circulation 20110301

Title: Human models of acute lung injury.

Journal: Disease models & mechanisms 20110301

Title: [Regional differences in the treatment of dyslipidemia in Germany].

Journal: Deutsche medizinische Wochenschrift (1946) 20110301

Title: The role of niacin in raising high-density lipoprotein cholesterol to reduce cardiovascular events in patients with atherosclerotic cardiovascular disease and optimally treated low-density lipoprotein cholesterol Rationale and study design. The Atherothrombosis Intervention in Metabolic syndrome with low HDL/high triglycerides: Impact on Global Health outcomes (AIM-HIGH).

Journal: American heart journal 20110301

Title: The role of niacin in raising high-density lipoprotein cholesterol to reduce cardiovascular events in patients with atherosclerotic cardiovascular disease and optimally treated low-density lipoprotein cholesterol: baseline characteristics of study participants. The Atherothrombosis Intervention in Metabolic syndrome with low HDL/high triglycerides: impact on Global Health outcomes (AIM-HIGH) trial.

Journal: American heart journal 20110301

Title: Host defense against viral infection involves interferon mediated down-regulation of sterol biosynthesis.

Journal: PLoS biology 20110301

Title: The implication of Sir2 in replicative aging and senescence in Saccharomyces cerevisiae.

Journal: Aging 20110301

Title: [Effects of Chinese herbal medicine Guanxinkang on lipid metabolism and serum C-reactive protein, amyloid A protein and fibrinogen in apolipoprotein E-knockout mice with atherosclerosis].

Journal: Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20110301

Title: Effect of simvastatin use on autonomic function in patients with end stage renal disease.

Journal: Cardiovascular & hematological disorders drug targets 20110301

Title: Dyslipidemia, low left ventricular ejection fraction and high wall motion score index are predictors of progressive left ventricular dilatation after acute myocardial infarction.

Journal: Korean circulation journal 20110301

Title: Comparison of Ezetimibe/Simvastatin 10/20 mg Versus Atorvastatin 20 mg in Achieving a Target Low Density Lipoprotein-Cholesterol Goal for Patients With Very High Risk.

Journal: Korean circulation journal 20110301

Title: Unusual cause of neurological symptoms in a young man.

Journal: JRSM short reports 20110301

Title: [Interindividual differences in the response to statin therapy and gene polymorphisms related to myopathy during statin therapy].

Journal: Giornale italiano di cardiologia (2006) 20110301

Title: Bilateral, simultaneous rupture of the quadriceps tendon associated with simvastatin.

Journal: The Israel Medical Association journal : IMAJ 20110301

Title: [Clinical study on simvastatin treatment of pulmonary hypertension in patients with coal worker's pneumoconiosis].

Journal: Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases 20110301

Title: Low-density lipoprotein cholesterol goal attainment among Malaysian dyslipidemic patients.

Journal: The Southeast Asian journal of tropical medicine and public health 20110301

Title: Performance evaluation of PAMAM dendrimer based simvastatin formulations.

Journal: International journal of pharmaceutics 20110227

Title: Broccoli ( Brassica oleracea var. italica) sprouts and extracts rich in glucosinolates and isothiocyanates affect cholesterol metabolism and genes involved in lipid homeostasis in hamsters.

Journal: Journal of agricultural and food chemistry 20110223

Title: Antiarrhythmic effects of simvastatin in canine pulmonary vein sleeve preparations.

Journal: Journal of the American College of Cardiology 20110222

Title: Statins reduce the androgen sensitivity and cell proliferation by decreasing the androgen receptor protein in prostate cancer cells.

Journal: The Prostate 20110215

Title: Use of cyclodextrins as solubilizing agents for simvastatin: effect of hydroxypropyl-β-cyclodextrin on lactone/hydroxyacid aqueous equilibrium.

Journal: International journal of pharmaceutics 20110214

Title: CRP: star trekking the galaxy of risk markers.

Journal: Lancet (London, England) 20110205

Title: C-reactive protein concentration and the vascular benefits of statin therapy: an analysis of 20,536 patients in the Heart Protection Study.

Journal: Lancet (London, England) 20110205

Title: Low doses of simvastatin therapy ameliorate cardiac inflammatory remodeling in Trypanosoma cruzi-infected dogs.

Journal: The American journal of tropical medicine and hygiene 20110204

Title: Effects of simvastatin therapy on circulating adipocytokines in patients with hypercholesterolemia.

Journal: International journal of cardiology 20110203

Title: Effect of niacin on preβ-1 high-density lipoprotein levels in diabetes.

Journal: Metabolism: clinical and experimental 20110201

Title: Using routinely collected prescribing data to determine drug persistence for the purpose of pharmacovigilance.

Journal: Journal of clinical pharmacology 20110201

Title: CYP3AP1*3 allele is associated with lipid-lowering efficacy of simvastatin and atorvastatin in Chinese women.

Journal: Journal of clinical pharmacology 20110201

Title: Multidrug donor preconditioning prevents cold liver preservation and reperfusion injury.

Journal: Langenbeck's archives of surgery 20110201

Title: Enhanced spectrophotometric determination of two antihyperlipidemic mixtures containing ezetimibe in pharmaceutical preparations.

Journal: Drug testing and analysis 20110201

Title: Simvastatin treatment reduces heat shock protein 60, 65, and 70 antibody titers in dyslipidemic patients: A randomized, double-blind, placebo-controlled, cross-over trial.

Journal: Clinical biochemistry 20110201

Title: Intensive lipid lowering in patients with rheumatoid arthritis and previous myocardial infarction: an explorative analysis from the incremental decrease in endpoints through aggressive lipid lowering (IDEAL) trial.

Journal: Rheumatology (Oxford, England) 20110201

Title: Anti-inflammatory and monocyte-suppressing effects of simvastatin in patients with impaired fasting glucose.

Journal: Basic & clinical pharmacology & toxicology 20110201

Title: Rapamycin, but not resveratrol or simvastatin, extends life span of genetically heterogeneous mice.

Journal: The journals of gerontology. Series A, Biological sciences and medical sciences 20110201

Title: Statin therapy in metabolic syndrome and hypertension post-JUPITER: what is the value of CRP?

Journal: Current atherosclerosis reports 20110201

Title: Simvastatin reduces lipoprotein-associated phospholipase A2 in lipopolysaccharide-stimulated human monocyte-derived macrophages through inhibition of the mevalonate-geranylgeranyl pyrophosphate-RhoA-p38 mitogen-activated protein kinase pathway.

Journal: Journal of cardiovascular pharmacology 20110201

Title: Anticancer efficacy of simvastatin on prostate cancer cells and tumor xenografts is associated with inhibition of Akt and reduced prostate-specific antigen expression.

Journal: The Journal of pharmacology and experimental therapeutics 20110201

Title: Drug metabolome of the simvastatin formed by human intestinal microbiota in vitro.

Journal: Molecular bioSystems 20110201

Title: Subtrochanteric fractures after long-term treatment with bisphosphonates: a European Society on Clinical and Economic Aspects of Osteoporosis and Osteoarthritis, and International Osteoporosis Foundation Working Group Report.

Journal: Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 20110201

Title: What combination therapy with a statin, if any, would you recommend?

Journal: Current atherosclerosis reports 20110201

Title: The anti-ischemic and anti-anginal properties of statins.

Journal: Current atherosclerosis reports 20110201

Title: OxLDL-dependent activation of arginase II is dependent on the LOX-1 receptor and downstream RhoA signaling.

Journal: Atherosclerosis 20110201

Title: Metamorphosis of subarachnoid hemorrhage research: from delayed vasospasm to early brain injury.

Journal: Molecular neurobiology 20110201

Title: Achievement of lipid targets with the combination of rosuvastatin and fenofibric Acid in patients with type 2 diabetes mellitus.

Journal: Cardiovascular drugs and therapy 20110201

Title: Approach to dyslipidemia, lipodystrophy, and cardiovascular risk in patients with HIV infection.

Journal: Current atherosclerosis reports 20110201

Title: Statin wars: efficacy vs. cost.

Journal: International journal of clinical practice 20110201

Title: Use of high-intensity statin therapy with simvastatin 80 mg and atorvastatin 80 mg in primary care.

Journal: International journal of clinical practice 20110201

Title: Dose-dependent effect of statins on the incidence of acute kidney injury after cardiac surgery.

Journal: The Annals of thoracic surgery 20110201

Title: Molecular mechanisms underlying the inhibition of IFN-γ-induced, STAT1-mediated gene transcription in human macrophages by simvastatin and agonists of PPARs and LXRs.

Journal: Journal of cellular biochemistry 20110201

Title: [Genetic marker of statin-induced rhabdomyolysis].

Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20110201

Title: Combination of prescribing restrictions and policies to engineer low prices to reduce reimbursement costs.

Journal: Expert review of pharmacoeconomics & outcomes research 20110201

Title: Assessment of coronary atherosclerosis by IVUS and IVUS-based imaging modalities: progression and regression studies, tissue composition and beyond.

Journal: The international journal of cardiovascular imaging 20110201

Title: If started early in life, metformin treatment increases life span and postpones tumors in female SHR mice.

Journal: Aging 20110201

Title: Linking nutrition, maturation and aging: from thrifty genes to the spendthrift phenotype.

Journal: Aging 20110201

Title: Long-term efficacy of adding fenofibric acid to moderate-dose statin therapy in patients with persistent elevated triglycerides.

Journal: Cardiovascular drugs and therapy 20110201

Title: [Effects of simvastatin on bone formation relative factors of trabecular bone and osteogenic differentiation of bone marrow mesenchymal stem cells in young rats].

Journal: Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery 20110201

Title: Gene expressions of nitric oxide synthase and matrix metalloproteinase-2 in monocrotaline-induced pulmonary hypertension in rats after bosentan treatment.

Journal: Korean circulation journal 20110201

Title: Lipid-lowering effects of ezetimibe and simvastatin in combination.

Journal: Expert review of cardiovascular therapy 20110201

Title: Combination therapy with ezetimibe/simvastatin versus statin monotherapy for low-density lipoprotein cholesterol reduction and goal attainment in a real-world clinical setting.

Journal: Clinical therapeutics 20110201

Title: Statin-associated myasthenic weakness.

Journal: Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20110201

Title: Letter: a retrospective study on the efficacy of a ten-milligram dosage of atorvastatin for treatment of hypercholesterolemia in type 2 diabetes mellitus patients (korean diabetes j 2010;34:359-67).

Journal: Diabetes & metabolism journal 20110201

Title: Response: a retrospective study on the efficacy of a ten-milligram dosage of atorvastatin for treatment of hypercholesterolemia in type 2 diabetes mellitus patients (korean diabetes j 2010;34:359-67).

Journal: Diabetes & metabolism journal 20110201

Title: [Retention behavior of statins in microemulsion liquid chromatography].

Journal: Se pu = Chinese journal of chromatography 20110201

Title: Economic evaluation of ezetimibe combined with simvastatin for the treatment of primary hypercholesterolaemia.

Journal: Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation 20110201

Title: Rosuvastatin reduces nonalcoholic fatty liver disease in patients with chronic hepatitis C treated with α-interferon and ribavirin: Rosuvastatin reduces NAFLD in HCV patients.

Journal: Hepatitis monthly 20110201

Title: Diagnosis and management of carbon monoxide poisoning in the emergency department.

Journal: Emergency medicine practice 20110201

Title: Ezetimibe, cardiovascular risk and atherogenic dyslipidaemia.

Journal: Archives of medical science : AMS 20110201

Title: Predictors of coronary intervention-related myocardial infarction in stable angina patients pre-treated with statins.

Journal: Archives of medical science : AMS 20110201

Title: A LDL-masked liposomal-doxorubicin reverses drug resistance in human cancer cells.

Journal: Journal of controlled release : official journal of the Controlled Release Society 20110120

Title: PBOX-15, a novel microtubule targeting agent, induces apoptosis, upregulates death receptors, and potentiates TRAIL-mediated apoptosis in multiple myeloma cells.

Journal: British journal of cancer 20110118

Title: Impact of smoking on cardiovascular events in patients with coronary disease receiving contemporary medical therapy (from the Treating to New Targets [TNT] and the Incremental Decrease in End Points Through Aggressive Lipid Lowering [IDEAL] trials).

Journal: The American journal of cardiology 20110115

Title: Simvastatin treatment improves functional recovery after experimental spinal cord injury by upregulating the expression of BDNF and GDNF.

Journal: Neuroscience letters 20110110

Title: Managing residual risk in patients receiving statin therapy.

Journal: The Medical journal of Australia 20110103

Title: Managing residual risk in patients receiving statin therapy. Comment.

Journal: The Medical journal of Australia 20110103

Title: HMC05, Herbal Formula, Inhibits TNF-α-Induced Inflammatory Response in Human Umbilical Vein Endothelial Cells.

Journal: Evidence-based complementary and alternative medicine : eCAM 20110101

Title: Simvastatin and Ginkgo biloba in the treatment of subacute tinnitus: a retrospective study of 94 patients.

Journal: American journal of otolaryngology 20110101

Title: A large observational study of cardiovascular outcomes associated with atorvastatin or simvastatin therapy in hypertensive patients without prior cardiovascular disease.

Journal: American journal of therapeutics 20110101

Title: Extra- and intra-ovarian factors in polycystic ovary syndrome: impact on oocyte maturation and embryo developmental competence.

Journal: Human reproduction update 20110101

Title: Statins: 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) reductase inhibitors demonstrate anti-atherosclerotic character due to their antioxidant capacity.

Journal: Applied biochemistry and biotechnology 20110101

Title: Acute mutism: a useful lesson.

Journal: Emergency medicine journal : EMJ 20110101

Title: Comparative neuroprotective profile of statins in quinolinic acid induced neurotoxicity in rats.

Journal: Behavioural brain research 20110101

Title: Statin reverses smoke-induced pulmonary hypertension and prevents emphysema but not airway remodeling.

Journal: American journal of respiratory and critical care medicine 20110101

Title: Differential response of endothelial cells to simvastatin when conditioned with steady, non-reversing pulsatile or oscillating shear stress.

Journal: Annals of biomedical engineering 20110101

Title: Potential prevention: orally administered statins may retard the pathologic process of disc degeneration.

Journal: Medical hypotheses 20110101

Title: Prospective randomized comparison between omega-3 fatty acid supplements plus simvastatin versus simvastatin alone in Korean patients with mixed dyslipidemia: lipoprotein profiles and heart rate variability.

Journal: European journal of clinical nutrition 20110101

Title: A randomised placebo-controlled double-blind trial to evaluate lipid-lowering pharmacotherapy on proteolysis and inflammation in abdominal aortic aneurysms.

Journal: European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery 20110101

Title: Pravastatin normalises peripheral cardiac sympathetic hyperactivity in the spontaneously hypertensive rat.

Journal: Journal of molecular and cellular cardiology 20110101

Title: Consumption of serum lipid-reducing drugs in Serbia compared with Scandinavian countries: a population-based study, 2004-2008.

Journal: Pharmacoepidemiology and drug safety 20110101

Title: Involvement of the p38 pathway in the differential induction of heme oxygenase-1 by statins in Neuro-2A cells exposed to lipopolysaccharide.

Journal: Drug and chemical toxicology 20110101

Title: Cleanup strategies and advantages in the determination of several therapeutic classes of pharmaceuticals in wastewater samples by SPE-LC-MS/MS.

Journal: Analytical and bioanalytical chemistry 20110101

Title: Comments regarding 'A randomised placebo-controlled double-blind trial to evaluate lipid-lowering pharmacotherapy on proteolysis and inflammation in abdominal aortic aneurysms'.

Journal: European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery 20110101

Title: Generation of human chiral metabolites of simvastatin and lovastatin by bacterial CYP102A1 mutants.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20110101

Title: Rosuvastatin for primary prevention in patients with European systematic coronary risk evaluation risk ≥ 5% or Framingham risk >20%: post hoc analyses of the JUPITER trial requested by European health authorities.

Journal: European heart journal 20110101

Title: RhoA/Rho kinase pathway contributes to the pathogenesis of thermal hyperalgesia in diabetic mice.

Journal: Pain 20110101

Title: Subacute-cutaneous lupus erythematosus induced by Simvastatin.

Journal: Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 20110101

Title: Zebrafish Tie-2 shares a redundant role with Tie-1 in heart development and regulates vessel integrity.

Journal: Disease models & mechanisms 20110101

Title: Use of ultra high performance liquid chromatography-tandem mass spectrometry to demonstrate decreased serum statin levels after extracorporeal LDL-cholesterol elimination.

Journal: Journal of biomedicine & biotechnology 20110101

Title: Differential efficiency of simvastatin and lipoic acid treatments on Bothrops jararaca envenomation-induced acute kidney injury in mice.

Journal: Toxicon : official journal of the International Society on Toxinology 20110101

Title: Statins as neuroprotectants: a comparative in vitro study of lipophilicity, blood-brain-barrier penetration, lowering of brain cholesterol, and decrease of neuron cell death.

Journal: Journal of Alzheimer's disease : JAD 20110101

Title: Statin-mediated reduction of osteopontin expression induces apoptosis and cell growth arrest in ovarian clear cell carcinoma.

Journal: Oncology reports 20110101

Title: Paradoxical decrease in HDL-cholesterol and apolipoprotein A1 with simvastatin and atorvastatin in a patient with type 2 diabetes.

Journal: Annals of clinical biochemistry 20110101

Title: Mechanisms of statin treatment in cerebral vasospasm.

Journal: Acta neurochirurgica. Supplement 20110101

Title: Increased inflammatory response in patients with dilated cardiomyopathy is associated with dyslipidemia: Effects of statin therapy.

Journal: Angiology 20110101

Title: Pitavastatin: a new 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitor for the treatment of hyperlipidemia.

Journal: Advances in therapy 20110101

Title: Statins have an early antiplatelet effect in patients with acute myocardial infarction.

Journal: Platelets 20110101

Title: The sequential combination of a JNK inhibitor and simvastatin protects porcine islets from peritransplant apoptosis and inflammation.

Journal: Cell transplantation 20110101

Title: Effect of hydroxymethylglutaryl-CoA reductase inhibitors on low-density lipoprotein cholesterol, interleukin-6, and high-sensitivity C-reactive protein in end-stage renal disease.

Journal: Iranian journal of kidney diseases 20110101

Title: The American Diabetes Association's 57th annual advanced postgraduate course: diabetes risk, vitamin D, polycystic ovary syndrome, and obstructive sleep apnea.

Journal: Diabetes care 20110101

Title: Standards of medical care in diabetes--2011.

Journal: Diabetes care 20110101

Title: Pharmacological treatment of obesity in children and adolescents: present and future.

Journal: Journal of obesity 20110101

Title: A Polypill for primary prevention of cardiovascular disease: a feasibility study of the World Health Organization.

Journal: Trials 20110101

Title: Periodic Fever syndromes.

Journal: Pediatric annals 20110101

Title: Autosomal-dominant Alzheimer's disease: a review and proposal for the prevention of Alzheimer's disease.

Journal: Alzheimer's research & therapy 20110101

Title: Preventing hospital admissions by reviewing medication (PHARM) in primary care: design of the cluster randomised, controlled, multi-centre PHARM-study.

Journal: BMC health services research 20110101

Title: Changes in the vascular cell adhesion molecule-1, intercellular adhesion molecule-1 and c-reactive protein following administration of aqueous extract of piper sarmentosum on experimental rabbits fed with cholesterol diet.

Journal: Lipids in health and disease 20110101

Title: RhoB loss prevents streptozotocin-induced diabetes and ameliorates diabetic complications in mice.

Journal: The American journal of pathology 20110101

Title: Simvastatin is the statin that most efficiently protects against kainate-induced excitotoxicity and memory impairment.

Journal: Journal of Alzheimer's disease : JAD 20110101

Title: Study design and rationale of 'Synergistic effect of combination therapy with cilostazol and ProbUcol on plaque stabilization and lesion REgression (SECURE)' study: a double-blind randomised controlled multicenter clinical trial.

Journal: Trials 20110101

Title: Statins for secondary prevention of cardiovascular disease: the right dose.

Journal: Pharmacology 20110101

Title: Understanding diabetes in patients with HIV/AIDS.

Journal: Diabetology & metabolic syndrome 20110101

Title: ADPKD: Prototype of Cardiorenal Syndrome Type 4.

Journal: International journal of nephrology 20110101

Title: Simvastatin reduces atherogenesis and promotes the expression of hepatic genes associated with reverse cholesterol transport in apoE-knockout mice fed high-fat diet.

Journal: Lipids in health and disease 20110101

Title: Synergistic effect of combined HMG-CoA reductase inhibitor and angiotensin-II receptor blocker therapy in patients with chronic heart failure: the HF-COSTAR trial.

Journal: Circulation journal : official journal of the Japanese Circulation Society 20110101

Title: Multi-modal proteomic analysis of retinal protein expression alterations in a rat model of diabetic retinopathy.

Journal: PloS one 20110101

Title: Novel adiponectin-resistin (AR) and insulin resistance (IRAR) indexes are useful integrated diagnostic biomarkers for insulin resistance, type 2 diabetes and metabolic syndrome: a case control study.

Journal: Cardiovascular diabetology 20110101

Title: Endothelial progenitor cells in long-standing asymptomatic type 1 diabetic patients with or without diabetic nephropathy.

Journal: Nephron. Clinical practice 20110101

Title: Involvement of protein kinase C and RhoA in protease-activated receptor 1-mediated F-actin reorganization and cell growth in rat cardiomyocytes.

Journal: Journal of pharmacological sciences 20110101

Title: Pathophysiology, treatment, and animal and cellular models of human ischemic stroke.

Journal: Molecular neurodegeneration 20110101

Title: Costarring statins with ARBs: going to be a smash hit?

Journal: Circulation journal : official journal of the Japanese Circulation Society 20110101

Title: Branch facial nerve trauma after superficial temporal artery biopsy: a case report.

Journal: Journal of medical case reports 20110101

Title: Paradoxical decrease in serum high-density lipoprotein cholesterol and lipid-lowering drugs.

Journal: Annals of clinical biochemistry 20110101

Title: Pharmacological and non-pharmacological interventions to influence adipose tissue function.

Journal: Cardiovascular diabetology 20110101

Title: Comparative effectiveness of guidelines for the management of hyperlipidemia and hypertension for type 2 diabetes patients.

Journal: PloS one 20110101

Title: Evaluating the effectiveness of rosuvastatin in preventing the progression of diastolic dysfunction in aortic stenosis: A substudy of the aortic stenosis progression observation measuring effects of rosuvastatin (ASTRONOMER) study.

Journal: Cardiovascular ultrasound 20110101

Title: Neuropathologic features in the hippocampus and cerebellum of three older men with fragile X syndrome.

Journal: Molecular autism 20110101

Title: Mevalonate cascade regulation of airway mesenchymal cell autophagy and apoptosis: a dual role for p53.

Journal: PloS one 20110101

Title: Cardiovascular prevention of cognitive decline.

Journal: Cardiology research and practice 20110101

Title: Packaging and labeling of pharmaceutical products obtained from the internet.

Journal: Journal of medical Internet research 20110101

Title: A phage-targeting strategy for the design of spatiotemporal drug delivery from grafted matrices.

Journal: Fibrogenesis & tissue repair 20110101

Title: The endotoxin-induced neuroinflammation model of Parkinson's disease.

Journal: Parkinson's disease 20110101

Title: Cardiorenal syndrome type 4-cardiovascular disease in patients with chronic kidney disease: epidemiology, pathogenesis, and management.

Journal: International journal of nephrology 20110101

Title: Assessment of elastase-induced murine abdominal aortic aneurysms: comparison of ultrasound imaging with in situ video microscopy.

Journal: Journal of biomedicine & biotechnology 20110101

Title: Restoration of cognitive deficits after statin feeding in TBI.

Journal: Restorative neurology and neuroscience 20110101

Title: Considering statins for cholesterol-reduction in children if lifestyle and diet changes do not improve their health: a review of the risks and benefits.

Journal: Vascular health and risk management 20110101

Title: ACE up the sleeve - are vascular patients medically optimized?

Journal: Vascular health and risk management 20110101

Title: Geranylgeranyl-pyrophosphate regulates secretion of pentraxin 3 and monocyte chemoattractant protein-1 from rheumatoid fibroblast-like synoviocytes in distinct manners.

Journal: Clinical and experimental rheumatology 20110101

Title: Aggressive cardiac involvement in systemic lupus erythematosus: a case report and a comprehensive literature review.

Journal: Cardiology research and practice 20110101

Title: Effects of currently prescribed LDL-C-lowering drugs on PCSK9 and implications for the next generation of LDL-C-lowering agents.

Journal: Lipids in health and disease 20110101

Title: Statins do not prevent acute organ failure in ventilated ICU patients: single-centre retrospective cohort study.

Journal: Critical care (London, England) 20110101

Title: Atorvastatin prevents Plasmodium falciparum cytoadherence and endothelial damage.

Journal: Malaria journal 20110101

Title: Effect of atorvastatin and clopidogrel co-administration after coronary stenting in korean patients with stable angina.

Journal: Korean circulation journal 20110101

Title: Influence of the association between simvastatin and demineralized bovine bone matrix on bone repair in rats.

Journal: Brazilian oral research 20110101

Title: Subjects with molecularly defined familial hypercholesterolemia or familial defective apoB-100 are not being adequately treated.

Journal: PloS one 20110101

Title: An effective assessment of simvastatin-induced toxicity with NMR-based metabonomics approach.

Journal: PloS one 20110101

Title: The interplay of inflammation and cardiovascular disease in systemic lupus erythematosus.

Journal: Arthritis research & therapy 20110101

Title: Simvastatin re-couples dysfunctional endothelial nitric oxide synthase in experimental subarachnoid hemorrhage.

Journal: PloS one 20110101

Title: Radiation recall pneumonitis induced by chemotherapy after thoracic radiotherapy for lung cancer.

Journal: Radiation oncology (London, England) 20110101

Title: Pravastatin versus simvastatin for prevention of contrast-induced nephropathy.

Journal: Journal of cardiovascular pharmacology and therapeutics 20110101

Title: Extracellular administration of BCL2 protein reduces apoptosis and improves survival in a murine model of sepsis.

Journal: PloS one 20110101

Title: Gut microbiome-host interactions in health and disease.

Journal: Genome medicine 20110101

Title: Fixed-dose combination fenofibrate/pravastatin 160/40 mg versus simvastatin 20 mg monotherapy in adults with type 2 diabetes and mixed hyperlipidemia uncontrolled with simvastatin 20 mg: a double-blind, randomized comparative study.

Journal: Clinical therapeutics 20110101

Title: Animal models of cardiovascular diseases.

Journal: Journal of biomedicine & biotechnology 20110101

Title: Lipoprotein(a) Is the Best Single Marker in Assessing Unstable Angina Pectoris.

Journal: Cardiology research and practice 20110101

Title: Progesterone administration modulates cortical TLR4/NF-κB signaling pathway after subarachnoid hemorrhage in male rats.

Journal: Mediators of inflammation 20110101

Title: Sex differences in drug disposition.

Journal: Journal of biomedicine & biotechnology 20110101

Title: Metabolic syndrome, chronic kidney disease, and cardiovascular disease: a dynamic and life-threatening triad.

Journal: Cardiology research and practice 20110101

Title: Changes in the organization of excitation-contraction coupling structures in failing human heart.

Journal: PloS one 20110101

Title: Cardiovascular safety of exenatide BID: an integrated analysis from controlled clinical trials in participants with type 2 diabetes.

Journal: Cardiovascular diabetology 20110101

Title: Residual beta cell function in newly diagnosed type 1 diabetes after treatment with atorvastatin: the Randomized DIATOR Trial.

Journal: PloS one 20110101

Title: ABCA1 and ABCG1 expressions are regulated by statins and ezetimibe in Caco-2 cells.

Journal: Drug metabolism and drug interactions 20110101

Title: Sustained remission of rheumatoid arthritis with a specific serotonin reuptake inhibitor antidepressant: a case report and review of the literature.

Journal: Journal of medical case reports 20110101

Title: Persistent lipid abnormalities in patients treated with statins: Portuguese results of the Dyslipidemia International Study (DYSIS).

Journal: Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology 20110101

Title: The animal model of spinal cord injury as an experimental pain model.

Journal: Journal of biomedicine & biotechnology 20110101

Title: [Prodrug technology in the development of medicinal agents].

Journal: Duodecim; laaketieteellinen aikakauskirja 20110101

Title: Neurovascular dysfunction, inflammation and endothelial activation: implications for the pathogenesis of Alzheimer's disease.

Journal: Journal of neuroinflammation 20110101

Title: Therapeutics formulated to target cancer stem cells: Is it in our future?

Journal: Cancer cell international 20110101

Title: Statins as modulators of colon cancer cells induced cytokine secretion by human PBMC.

Journal: Vascular pharmacology 20110101

Title: Lymphocyte-suppressing effect of simvastatin in mixed dyslipidemic patients but not impaired glucose tolerance patients.

Journal: Pharmacological reports : PR 20110101

Title: Understanding hypertriglyceridemia in women: clinical impact and management with prescription omega-3-acid ethyl esters.

Journal: International journal of women's health 20110101

Title: Are all statins the same? Focus on the efficacy and tolerability of pitavastatin.

Journal: American journal of cardiovascular drugs : drugs, devices, and other interventions 20110101

Title: Glibenclamide or metformin combined with honey improves glycemic control in streptozotocin-induced diabetic rats.

Journal: International journal of biological sciences 20110101

Title: Characterization of human erythrocytes as potential carrier for pravastatin: an in vitro study.

Journal: International journal of medical sciences 20110101

Title: Cost effectiveness and cost utility of the noncoding blood glucose meter CONTOUR TS.

Journal: Diabetes, metabolic syndrome and obesity : targets and therapy 20110101

Title: Apolipoprotein E epsilon-4 polymorphism is associated with younger age at referral to a lipidology clinic and a poorer response to lipid-lowering therapy.

Journal: Lipids in health and disease 20110101

Title: Aspirin effect on the incidence of major adverse cardiovascular events in patients with diabetes mellitus: a systematic review and meta-analysis.

Journal: Cardiovascular diabetology 20110101

Title: Morphological changes of parotid gland in experimental hyperlipidemia.

Journal: International journal of dentistry 20110101

Title: Statins: cardiovascular risk reduction in percutaneous coronary intervention-basic and clinical evidence of hyperacute use of statins.

Journal: International journal of hypertension 20110101

Title: Protocol for the ADDITION-Plus study: a randomised controlled trial of an individually-tailored behaviour change intervention among people with recently diagnosed type 2 diabetes under intensive UK general practice care.

Journal: BMC public health 20110101

Title: Psoriasis carries an increased risk of venous thromboembolism: a Danish nationwide cohort study.

Journal: PloS one 20110101

Title: Ticagrelor: the evidence for its clinical potential as an oral antiplatelet treatment for the reduction of major adverse cardiac events in patients with acute coronary syndromes.

Journal: Core evidence 20110101

Title: Preparation and evaluation of ofloxacin-loaded palmitic acid solid lipid nanoparticles.

Journal: International journal of nanomedicine 20110101

Title: Effect of statin treatment on short term mortality after pneumonia episode: cohort study.

Journal: BMJ (Clinical research ed.) 20110101

Title: Clinical utility of rosuvastatin and other statins for cardiovascular risk reduction among the elderly.

Journal: Clinical interventions in aging 20110101

Title: Effects of short-term treatment with atorvastatin in smokers with asthma--a randomized controlled trial.

Journal: BMC pulmonary medicine 20110101

Title: NCI60 cancer cell line panel data and RNAi analysis help identify EAF2 as a modulator of simvastatin and lovastatin response in HCT-116 cells.

Journal: PloS one 20110101

Title: A new pathway of glucocorticoid action for asthma treatment through the regulation of PTEN expression.

Journal: Respiratory research 20110101

Title: Statins: a role in infected critically ill patients?

Journal: Critical care (London, England) 20110101

Title: Carriage of the V279F null allele within the gene encoding Lp-PLA₂ is protective from coronary artery disease in South Korean males.

Journal: PloS one 20110101

Title: Liposome technology for industrial purposes.

Journal: Journal of drug delivery 20110101

Title: Rhabdomyolysis-induced acute renal failure due to itraconazole and simvastatin association.

Journal: Drug metabolism and drug interactions 20110101

Title: Granulocyte-CSF induced inflammation-associated cardiac thrombosis in iron loading mouse heart and can be attenuated by statin therapy.

Journal: Journal of biomedical science 20110101

Title: Trends in utilization of lipid- and blood pressure-lowering agents and goal attainment among the U.S. diabetic population, 1999-2008.

Journal: Cardiovascular diabetology 20110101

Title: Cigarette smoke exacerbates mouse allergic asthma through Smad proteins expressed in mast cells.

Journal: Respiratory research 20110101

Title: Influence of polymorphisms and cholesterol-lowering treatment on SCARB1 mRNA expression.

Journal: Journal of atherosclerosis and thrombosis 20110101

Title: Peripheral endothelial dysfunction is associated with gas exchange inefficiency in smokers.

Journal: Respiratory research 20110101

Title: Iterative CT reconstruction of aortic intramural hematoma.

Journal: Circulation journal : official journal of the Japanese Circulation Society 20110101

Title: Pitavastatin increases ABCA1 expression by dual mechanisms: SREBP2-driven transcriptional activation and PPARα-dependent protein stabilization but without activating LXR in rat hepatoma McARH7777 cells.

Journal: Journal of pharmacological sciences 20110101

Title: Simvastatin suppresses dexamethasone-induced secretion of plasminogen activator inhibitor-1 in human bone marrow adipocytes.

Journal: BMC musculoskeletal disorders 20110101

Title: Network modeling of the transcriptional effects of copy number aberrations in glioblastoma.

Journal: Molecular systems biology 20110101

Title: Serum lipoprotein levels in takotsubo cardiomyopathy vs. myocardial infarction.

Journal: International archives of medicine 20110101

Title: A novel AMPK activator, WS070117, improves lipid metabolism discords in hamsters and HepG2 cells.

Journal: Lipids in health and disease 20110101

Title: Antineoplastic effects of simvastatin in experimental breast cancer.

Journal: Klinicka onkologie : casopis Ceske a Slovenske onkologicke spolecnosti 20110101

Title: Investigational drugs for the treatment of AD: what can we learn from negative trials?

Journal: Alzheimer's research & therapy 20110101

Title: Pre-admission statin use and in-hospital severity of 2009 pandemic influenza A(H1N1) disease.

Journal: PloS one 20110101

Title: Roles of the WHHL rabbit in translational research on hypercholesterolemia and cardiovascular diseases.

Journal: Journal of biomedicine & biotechnology 20110101

Title: A systems biology approach to dynamic modeling and inter-subject variability of statin pharmacokinetics in human hepatocytes.

Journal: BMC systems biology 20110101

Title: S1P, dihydro-S1P and C24:1-ceramide levels in the HDL-containing fraction of serum inversely correlate with occurrence of ischemic heart disease.

Journal: Lipids in health and disease 20110101

Title: Pleiotropic effects of the HMG-CoA reductase inhibitors.

Journal: International journal of general medicine 20110101

Title: Development and optimization of solid lipid nanoparticle formulation for ophthalmic delivery of chloramphenicol using a Box-Behnken design.

Journal: International journal of nanomedicine 20110101

Title: Primary prevention with statins is more cost-effective.

Journal: Cardiovascular journal of Africa 20110101

Title: Function and comorbidities of apolipoprotein e in Alzheimer's disease.

Journal: International journal of Alzheimer's disease 20110101

Title: Coordinately regulated alternative splicing of genes involved in cholesterol biosynthesis and uptake.

Journal: PloS one 20110101

Title: Increased levels of leukocyte-derived MMP-9 in patients with stable angina pectoris.

Journal: PloS one 20110101

Title: Clinical use and effectiveness of lipid lowering therapies in diabetes mellitus--an observational study from the Swedish National Diabetes Register.

Journal: PloS one 20110101

Title: Bioactivities of berberine metabolites after transformation through CYP450 isoenzymes.

Journal: Journal of translational medicine 20110101

Title: Exercise and spirulina control non-alcoholic hepatic steatosis and lipid profile in diabetic Wistar rats.

Journal: Lipids in health and disease 20110101

Title: AGE-BSA down-regulates endothelial connexin43 gap junctions.

Journal: BMC cell biology 20110101

Title: Pharmacological management of atrial fibrillation: one, none, one hundred thousand.

Journal: Cardiology research and practice 20110101

Title: Influence of simvastatin, fenofibrate and/or ezetimibe on correlation of low-density lipoprotein and nonhigh-density lipoprotein cholesterol with apolipoprotein B in mixed dyslipidemic patients.

Journal: Journal of clinical lipidology 20110101

Title: Design and evaluation of self-nanoemulsifying drug delivery system of flutamide.

Journal: Journal of young pharmacists : JYP 20110101

Title: No connection between the level of exposition to statins in the population and the incidence/mortality of acute myocardial infarction: an ecological study based on Sweden's municipalities.

Journal: Journal of negative results in biomedicine 20110101

Title: Harnessing expression data to identify novel candidate genes in polycystic ovary syndrome.

Journal: PloS one 20110101

Title: A case of xanthoma disseminatum with spontaneous resolution over 10 years: review of the literature on long-term follow-up.

Journal: Dermatology (Basel, Switzerland) 20110101

Title: Place of pitavastatin in the statin armamentarium: promising evidence for a role in diabetes mellitus.

Journal: Drug design, development and therapy 20110101

Title: Chronic oral infection with Porphyromonas gingivalis accelerates atheroma formation by shifting the lipid profile.

Journal: PloS one 20110101

Title: Concentration independent modulation of local micromechanics in a fibrin gel.

Journal: PloS one 20110101

Title: Concomitant use of simvastatin and amiodarone resulting in severe rhabdomyolysis: a case report and review of the literature.

Journal: Acta clinica Belgica 20110101

Title: Dyslipidemia associated with chronic kidney disease.

Journal: The open cardiovascular medicine journal 20110101

Title: HIV and HAART-Associated Dyslipidemia.

Journal: The open cardiovascular medicine journal 20110101

Title: An international randomised placebo-controlled trial of a four-component combination pill ('polypill') in people with raised cardiovascular risk.

Journal: PloS one 20110101

Title: Effects of thyroid dysfunction on lipid profile.

Journal: The open cardiovascular medicine journal 20110101

Title: Dyslipidaemia of obesity, metabolic syndrome and type 2 diabetes mellitus: the case for residual risk reduction after statin treatment.

Journal: The open cardiovascular medicine journal 20110101

Title: Awareness of Abdominal Adiposity as a Cardiometabolic Risk Factor (The 5A Study): Mexico.

Journal: Diabetes, metabolic syndrome and obesity : targets and therapy 20110101

Title: Pharmacological management of cardiorenal syndromes.

Journal: International journal of nephrology 20110101

Title: Clinical characteristics and evaluation of LDL-cholesterol treatment of the Spanish Familial Hypercholesterolemia Longitudinal Cohort Study (SAFEHEART).

Journal: Lipids in health and disease 20110101

Title: Does atorvastatin work more effectively than biguanides in reducing cardiovascular risk factors?

Journal: Journal of pharmacy & bioallied sciences 20110101

Title: Visfatin is regulated by rosiglitazone in type 2 diabetes mellitus and influenced by NFκB and JNK in human abdominal subcutaneous adipocytes.

Journal: PloS one 20110101

Title: Pathogenesis of the cutaneous phenotype in inherited disorders of cholesterol metabolism: Therapeutic implications for topical treatment of these disorders.

Journal: Dermato-endocrinology 20110101

Title: Relationship between a novel polymorphism of the C5L2 gene and coronary artery disease.

Journal: PloS one 20110101

Title: Classical risk factors of cardiovascular disease among Chinese male steel workers: a prospective cohort study for 20 years.

Journal: BMC public health 20110101

Title: Patient and general practitioner attitudes to taking medication to prevent cardiovascular disease after receiving detailed information on risks and benefits of treatment: a qualitative study.

Journal: BMC family practice 20110101

Title: Effects of HMG-CoA reductase inhibitors on the pharmacokinetics of losartan and its main metabolite EXP-3174 in rats: possible role of CYP3A4 and P-gp inhibition by HMG-CoA reductase inhibitors.

Journal: Pharmacology 20110101

Title: Ageusia as a side effect of clopidogrel treatment.

Journal: Indian journal of pharmacology 20110101

Title: Improvement in endothelial dysfunction in patients with systemic lupus erythematosus with N-acetylcysteine and atorvastatin.

Journal: Indian journal of pharmacology 20110101

Title: The effect of simvastatin in penile erection: a randomized, double-blind, placebo-controlled clinical trial (Simvastatin treatment for erectile dysfunction-STED TRIAL).

Journal: International journal of impotence research 20110101

Title: Asystole following positive pressure insufflation of right pleural cavity: a case report.

Journal: Journal of medical case reports 20110101

Title: Cardiovascular co-morbidity in patients with rheumatic diseases.

Journal: Arthritis research & therapy 20110101

Title: Generation of polyclonal antibody with high avidity to rosuvastatin and its use in development of highly sensitive ELISA for determination of rosuvastatin in plasma.

Journal: Chemistry Central journal 20110101

Title: Effects of simvastatin on apolipoprotein M in vivo and in vitro.

Journal: Lipids in health and disease 20110101

Title: Simvastatin prevents dopaminergic neurodegeneration in experimental parkinsonian models: the association with anti-inflammatory responses.

Journal: PloS one 20110101

Title: Simvastatin-induced meralgia paresthetica.

Journal: Journal of the American Board of Family Medicine : JABFM 20110101

Title: Add-on-Statin Extended Release Nicotinic Acid/Laropiprant but Not the Switch to High-Dose Rosuvastatin Lowers Blood Pressure: An Open-Label Randomized Study.

Journal: International journal of hypertension 20110101

Title: Secondary Pharmacotherapeutic Prevention among German Primary Care Patients with Peripheral Arterial Disease.

Journal: International journal of vascular medicine 20110101

Title: Left ventricular hypertrophy: major risk factor in patients with hypertension: update and practical clinical applications.

Journal: International journal of hypertension 20110101

Title: Double-blind, randomized, multicentre, and active comparator controlled investigation of the effect of pioglitazone, metformin, and the combination of both on cardiovascular risk in patients with type 2 diabetes receiving stable basal insulin therapy: the PIOCOMB study.

Journal: Cardiovascular diabetology 20110101

Title: Effects of improving glycemic control with insulin on leptin, adiponectin, ghrelin and neuropeptidey levels in patients with type 2 diabetes mellitus: a pilot study.

Journal: The open cardiovascular medicine journal 20110101

Title: Diabetes mellitus and cardiovascular prevention: the role and the limitations of currently available antiplatelet drugs.

Journal: International journal of vascular medicine 20110101

Title: Dyslipidemia induced by drugs used for the prevention and treatment of vascular diseases.

Journal: The open cardiovascular medicine journal 20110101

Title: Evaluation of plaque stability of advanced atherosclerotic lesions in apo E-deficient mice after treatment with the oral factor Xa inhibitor rivaroxaban.

Journal: Mediators of inflammation 20110101

Title: The gut microbiota and human health with an emphasis on the use of microencapsulated bacterial cells.

Journal: Journal of biomedicine & biotechnology 20110101

Title: Effective Delivery of PEGylated siRNA-Containing Lipoplexes to Extraperitoneal Tumours following Intraperitoneal Administration.

Journal: Journal of drug delivery 20110101

Title: Nonalcoholic Fatty liver disease: focus on lipoprotein and lipid deregulation.

Journal: Journal of lipids 20110101

Title: Stem cells for cardiac repair: status, mechanisms, and new strategies.

Journal: Stem cells international 20110101

Title: Treating statin-intolerant patients.

Journal: Diabetes, metabolic syndrome and obesity : targets and therapy 20110101

Title: Concordance between plasma apolipoprotein B levels and cholesterol indices among patients receiving statins and nonstatin treatment: Post-hoc analyses from the U.K. InPractice study.

Journal: Journal of clinical lipidology 20110101

Title: Antiamnesic activity of an ayurvedic formulation chyawanprash in mice.

Journal: Evidence-based complementary and alternative medicine : eCAM 20110101

Title: Adherence with statins in a real-life setting is better when associated cardiovascular risk factors increase: a cohort study.

Journal: BMC cardiovascular disorders 20110101

Title: Primary prevention of coronary heart disease: integration of new data, evolving views, revised goals, and role of rosuvastatin in management. A comprehensive survey.

Journal: Drug design, development and therapy 20110101

Title: Antiatherogenic Potential of Nigella sativa Seeds and Oil in Diet-Induced Hypercholesterolemia in Rabbits.

Journal: Evidence-based complementary and alternative medicine : eCAM 20110101

Title: The roles of buyang huanwu decoction in anti-inflammation, antioxidation and regulation of lipid metabolism in rats with myocardial ischemia.

Journal: Evidence-based complementary and alternative medicine : eCAM 20110101

Title: Depression in vascular pathologies: the neurologist's point of view.

Journal: Vascular health and risk management 20110101

Title: Effect of moderate and high dose simvastatin on adhesion molecules in severe hypercholesterolemia after targeting the LDL-cholesterol--a randomised, placebo-controlled study.

Journal: Folia medica 20110101

Title: δ-Sarcoglycan-deficient muscular dystrophy: from discovery to therapeutic approaches.

Journal: Skeletal muscle 20110101

Title: Influence of a probiotic soy product on fecal microbiota and its association with cardiovascular risk factors in an animal model.

Journal: Lipids in health and disease 20110101

Title: Suboptimal use of risk reduction therapy in peripheral arterial disease patients at a major teaching hospital.

Journal: Annals of Saudi medicine 20110101

Title: Downregulation of the proinflammatory state of circulating mononuclear cells by short-term treatment with pioglitazone in patients with type 2 diabetes mellitus and coronary artery disease.

Journal: PPAR research 20110101

Title: The role of soluble fiber intake in patients under highly effective lipid-lowering therapy.

Journal: Nutrition journal 20110101

Title: Processing of endogenous AβPP in blood-brain barrier endothelial cells is modulated by liver-X receptor agonists and altered cellular cholesterol homeostasis.

Journal: Journal of Alzheimer's disease : JAD 20110101

Title: Carotid plaque regression following 6-month statin therapy assessed by 3T cardiovascular magnetic resonance: comparison with ultrasound intima media thickness.

Journal: Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance 20110101

Title: Accumulation and aberrant composition of cholesteryl esters in Scrapie-infected N2a cells and C57BL/6 mouse brains.

Journal: Lipids in health and disease 20110101

Title: Association between statin therapy and outcomes in critically ill patients: a nested cohort study.

Journal: BMC clinical pharmacology 20110101

Title: Anti-inflammatory effect of fluvastatin on IL-8 production induced by Pseudomonas aeruginosa and Aspergillus fumigatus antigens in cystic fibrosis.

Journal: PloS one 20110101

Title: Animal models of calcific aortic valve disease.

Journal: International journal of inflammation 20110101

Title: Coenzyme Q10 levels are low and may be associated with the inflammatory cascade in septic shock.

Journal: Critical care (London, England) 20110101

Title: A 64-year old man presenting with carotid artery occlusion and corticobasal syndrome: a case report.

Journal: Journal of medical case reports 20110101

Title: Recurrent, sequential, bilateral deep cerebellar hemorrhages: a case report.

Journal: Journal of medical case reports 20110101

Title: Statin-induced apoptosis via the suppression of ERK1/2 and Akt activation by inhibition of the geranylgeranyl-pyrophosphate biosynthesis in glioblastoma.

Journal: Journal of experimental & clinical cancer research : CR 20110101

Title: Alopecia areata: a new treatment plan.

Journal: Clinical, cosmetic and investigational dermatology 20110101

Title: A systems biology strategy for predicting similarities and differences of drug effects: evidence for drug-specific modulation of inflammation in atherosclerosis.

Journal: BMC systems biology 20110101

Title: [Analysis of cost-effectiveness of simvastatin versus atorvastatin in the secondary prevention of cardiovascular events within the Brazilian public healthcare system].

Journal: Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research 20110101

Title: Tacrolimus and 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors: An interaction study in CYP3A5 non-expressors, renal transplant recipients.

Journal: Indian journal of pharmacology 20110101

Title: Comparative efficacy of ezetimibe/simvastatin, rosuvastatin, and atorvastatin in uncontrolled hyperlipidemia patients.

Journal: The American journal of managed care 20110101

Title: Paraoxonase (PON1 and PON3) Polymorphisms: Impact on Liver Expression and Atorvastatin-Lactone Hydrolysis.

Journal: Frontiers in pharmacology 20110101

Title: Response by sex to statin plus ezetimibe or statin monotherapy: a pooled analysis of 22,231 hyperlipidemic patients.

Journal: Lipids in health and disease 20110101

Title: [Antioxidant enzymes in erythrocytes from hypertension patients receiving lisinopril monotherapy or combined lisinopril plus simvastatin therapy].

Journal: Biomeditsinskaia khimiia 20110101

Title: Simvastatin inhibits TGFβ1-induced fibronectin in human airway fibroblasts.

Journal: Respiratory research 20110101

Title: Treatment of allergic asthma: modulation of Th2 cells and their responses.

Journal: Respiratory research 20110101

Title: Evaluation of the global association between cholesterol-associated polymorphisms and Alzheimer's disease suggests a role for rs3846662 and HMGCR splicing in disease risk.

Journal: Molecular neurodegeneration 20110101

Title: Developmental patterns and characteristics of epicardial cell markers Tbx18 and Wt1 in murine embryonic heart.

Journal: Journal of biomedical science 20110101

Title: Protein kinase C and toll-like receptor signaling.

Journal: Enzyme research 20110101

Title: Age-related white matter changes.

Journal: Journal of aging research 20110101

Title: Antioxidant vitamins in the prevention of atrial fibrillation: what is the evidence?

Journal: Cardiology research and practice 20110101

Title: Safe use of ezetimibe plus simvastatin in high-risk vascular patients (with chronic kidney disease and PAD).

Journal: Cardiovascular journal of Africa 20110101

Title: Stepwise approach to myopathy in systemic disease.

Journal: Frontiers in neurology 20110101

Title: Spinal cord injury: From inflammation to glial scar.

Journal: Surgical neurology international 20110101

Title: Synthesis, characterization and quantification of simvastatin metabolites and impurities.

Journal: Scientia pharmaceutica 20110101

Title: Prerenal azotemia from excessive sweating in an adult with a cystic fibrosis gene mutation.

Journal: Indian journal of nephrology 20110101

Title: Emerging therapies for severe asthma.

Journal: BMC medicine 20110101

Title: Simvastatin displays an antioxidative effect by inhibiting an increase in the serum 8-isoprostane level in patients with acute ischemic stroke: brief report.

Journal: Clinical neuropharmacology 20110101

Title: Tumor cell-selective apoptosis induction through targeting of K(V)10.1 via bifunctional TRAIL antibody.

Journal: Molecular cancer 20110101

Title: Probucol attenuates oxidative stress, energy starvation, and nitric acid production following transient forebrain ischemia in the rat hippocampus.

Journal: Oxidative medicine and cellular longevity 20110101

Title: Incidence of pancreatitis, secondary causes, and treatment of patients referred to a specialty lipid clinic with severe hypertriglyceridemia: a retrospective cohort study.

Journal: Lipids in health and disease 20110101

Title: Simvastatin improves spinal fusion in rats.

Journal: Acta orthopaedica et traumatologica turcica 20110101

Title: Contrast-induced nephropathy in interventional cardiology.

Journal: International journal of nephrology and renovascular disease 20110101

Title: Studies on the antibacterial effects of statins--in vitro and in vivo.

Journal: PloS one 20110101

Title: Rituximab resistant evans syndrome and autoimmunity in Schimke immuno-osseous dysplasia.

Journal: Pediatric rheumatology online journal 20110101

Title: Renal artery stenosis in kidney transplants: assessment of the risk factors.

Journal: Vascular health and risk management 20110101

Title: Lipid-lowering therapy: who can benefit?

Journal: Vascular health and risk management 20110101

Title: Extended-release ranolazine: critical evaluation of its use in stable angina.

Journal: Vascular health and risk management 20110101

Title: Vascular inflammation and endothelial dysfunction in experimental hypertension.

Journal: International journal of hypertension 20110101

Title: Potential role of differential medication use in explaining excess risk of cardiovascular events and death associated with chronic kidney disease: a cohort study.

Journal: BMC nephrology 20110101

Title: 5-α reductase inhibitors and prostate cancer prevention: where do we turn now?

Journal: BMC medicine 20110101

Title: Cardiac medication prescribing and adherence after acute myocardial infarction in Chinese and South Asian Canadian patients.

Journal: BMC cardiovascular disorders 20110101

Title: Egr-1 induces a profibrotic injury/repair gene program associated with systemic sclerosis.

Journal: PloS one 20110101

Title: Statins enhance clonal growth of late outgrowth endothelial progenitors and increase myocardial capillary density in the chronically ischemic heart.

Journal: PloS one 20110101

Title: Effects of simvastatin in patients with viral chronic hepatitis C.

Journal: Hepato-gastroenterology 20110101

Title: Short-term effect of fenofibrate on C-reactive protein: A meta-analysis of randomized controlled trials.

Journal: Diabetology & metabolic syndrome 20110101

Title: Atrioventricular dissociation after electroconvulsive therapy.

Journal: Cardiology research and practice 20110101

Title: [Association of a polymorphic marker Trp719Arg of KIF6 gene with effects of atorvastatin and simvastatin in patients with early ischemic heart disease].

Journal: Kardiologiia 20110101

Title: Exposure to statins and risk of common cancers: a series of nested case-control studies.

Journal: BMC cancer 20110101

Title: Promoting knowledge of statins in patients with low health literacy using an audio booklet.

Journal: Patient preference and adherence 20110101

Title: Long-term use and tolerability of irbesartan for control of hypertension.

Journal: Integrated blood pressure control 20110101

Title: Administration of simvastatin after kainic acid-induced status epilepticus restrains chronic temporal lobe epilepsy.

Journal: PloS one 20110101

Title: Effect of simvastatin on expression of transforming growth factor-β and collagen type IV in rat mesangial cells.

Journal: Pharmacology 20110101

Title: Antioxidant and inflammatory aspects of lipoprotein-associated phospholipase A₂ (Lp-PLA₂): a review.

Journal: Lipids in health and disease 20110101

Title: Activated microglia inhibit axonal growth through RGMa.

Journal: PloS one 20110101

Title: The effects of simvastatin on left ventricular hypertrophy and left ventricular function in patients with essential hypertension.

Journal: Clinical and experimental hypertension (New York, N.Y. : 1993) 20110101

Title: A retrospective cohort study of the potency of lipid-lowering therapy and race-gender differences in LDL cholesterol control.

Journal: BMC cardiovascular disorders 20110101

Title: Quality of online pharmacies and websites selling prescription drugs: a systematic review.

Journal: Journal of medical Internet research 20110101

Title: Prevalence, Predictors, and Impact of Low High-Density Lipoprotein Cholesterol on in-Hospital Outcomes Among Acute Coronary Syndrome Patients in the Middle East.

Journal: The open cardiovascular medicine journal 20110101

Title: Serum lipid profiles are associated with disability and MRI outcomes in multiple sclerosis.

Journal: Journal of neuroinflammation 20110101

Title: Prevalence of peripheral arterial disease in subjects with moderate cardiovascular risk: Italian results from the PANDORA study Data from PANDORA (Prevalence of peripheral Arterial disease in subjects with moderate CVD risk, with No overt vascular Diseases nor Diabetes mellitus).

Journal: BMC cardiovascular disorders 20110101

Title: Predicting P-glycoprotein-mediated drug transport based on support vector machine and three-dimensional crystal structure of P-glycoprotein.

Journal: PloS one 20110101

Title: Effectiveness of Ezetimibe in Reducing the Estimated Risk for Fatal Cardiovascular Events in Hypercholesterolaemic Patients with Inadequate Lipid Control While on Statin Monotherapy as Measured by the SCORE Model.

Journal: Advances in preventive medicine 20110101

Title: Ectopic hepatic tissue presented as a posterior mediastinal mass.

Journal: ISRN gastroenterology 20110101

Title: SLCO1B1 rs4149056 polymorphism associated with statin-induced myopathy is differently distributed according to ethnicity in the Brazilian general population: Amerindians as a high risk ethnic group.

Journal: BMC medical genetics 20110101

Title: Comparative study on saponin fractions from Panax notoginseng inhibiting inflammation-induced endothelial adhesion molecule expression and monocyte adhesion.

Journal: Chinese medicine 20110101

Title: Pleiotropic effects of statins in distal human pulmonary artery smooth muscle cells.

Journal: Respiratory research 20110101

Title: Risk factors associated with symptomatic cholelithiasis in Taiwan: a population-based study.

Journal: BMC gastroenterology 20110101

Title: Challenges associated with tyrosine kinase inhibitor therapy for metastatic thyroid cancer.

Journal: Journal of thyroid research 20110101

Title: Pharmacogenetics of OATP transporters reveals that SLCO1B1 c.388A>G variant is determinant of increased atorvastatin response.

Journal: International journal of molecular sciences 20110101

Title: Different impacts of cardiovascular risk factors on oxidative stress.

Journal: International journal of molecular sciences 20110101

Title: Fabrication, modeling and characterization of multi-crosslinked methacrylate copolymeric nanoparticles for oral drug delivery.

Journal: International journal of molecular sciences 20110101

Title: Multimodal cardiovascular magnetic resonance quantifies regional variation in vascular structure and function in patients with coronary artery disease: relationships with coronary disease severity.

Journal: Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance 20110101

Title: Effects of statin medication on mortality risk associated with type 2 diabetes in older persons: the population-based AGES-Reykjavik Study.

Journal: BMJ open 20110101

Title: Enteric microbiome metabolites correlate with response to simvastatin treatment.

Journal: PloS one 20110101

Title: Platelets in patients with premature coronary artery disease exhibit upregulation of miRNA340* and miRNA624*.

Journal: PloS one 20110101

Title: Effects of atorvastatin and rosuvastatin on high-sensitivity C-reactive protein and lipid profile in obese type 2 diabetes mellitus patients.

Journal: Journal of pharmacology & pharmacotherapeutics 20110101

Title: Sick sinus syndrome associated with topical timolol maleate instillation.

Journal: Journal of pharmacology & pharmacotherapeutics 20110101

Title: Viscum album exerts anti-inflammatory effect by selectively inhibiting cytokine-induced expression of cyclooxygenase-2.

Journal: PloS one 20110101

Title: South Asian Consensus Guidelines for the rational management of diabetes in human immunodeficiency virus/acquired immunodeficiency syndrome.

Journal: Indian journal of endocrinology and metabolism 20110101

Title: Diagnostic markers based on a computational model of lipoprotein metabolism.

Journal: Journal of clinical bioinformatics 20110101

Title: Protein trafficking dysfunctions: Role in the pathogenesis of pulmonary arterial hypertension.

Journal: Pulmonary circulation 20110101

Title: Combination use of sildenafil and simvastatin increases BMPR-II signal transduction in rats with monocrotaline-mediated pulmonary hypertension.

Journal: Pulmonary circulation 20110101

Title: Estimated glomerular filtration rate and the risk of major vascular events and all-cause mortality: a meta-analysis.

Journal: PloS one 20110101

Title: Unilateral thalamic infarction presenting as vertical gaze palsy: a case report.

Journal: Journal of medical case reports 20110101

Title: Rho kinase inhibition by fasudil has anti-inflammatory effects in hypercholesterolemic rats.

Journal: Biological & pharmaceutical bulletin 20110101

Title: Current status of immunomodulatory and cellular therapies in preclinical and clinical islet transplantation.

Journal: Journal of transplantation 20110101

Title: Role of magnesium sulfate in aneurysmal subarachnoid hemorrhage management: A meta-analysis of controlled clinical trials.

Journal: Asian journal of neurosurgery 20110101

Title: Effects of acute ingestion of different fats on oxidative stress and inflammation in overweight and obese adults.

Journal: Nutrition journal 20110101

Title: Prevalence of microscopic colitis in patients with chronic diarrhea in Egypt: a single-center study.

Journal: Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association 20110101

Title: Activation of Sirt1 by resveratrol inhibits TNF-α induced inflammation in fibroblasts.

Journal: PloS one 20110101

Title: In situ formation of nanocrystals from a self-microemulsifying drug delivery system to enhance oral bioavailability of fenofibrate.

Journal: International journal of nanomedicine 20110101

Title: Camphene, a plant-derived monoterpene, reduces plasma cholesterol and triglycerides in hyperlipidemic rats independently of HMG-CoA reductase activity.

Journal: PloS one 20110101

Title: Predicting in vivo anti-hepatofibrotic drug efficacy based on in vitro high-content analysis.

Journal: PloS one 20110101

Title: An essential farnesylated kinesin in Trypanosoma brucei.

Journal: PloS one 20110101

Title: Unmasking differential effects of rosiglitazone and pioglitazone in the combination treatment with n-3 fatty acids in mice fed a high-fat diet.

Journal: PloS one 20110101

Title: Apolipoprotein E mRNA expression in mononuclear cells from normolipidemic and hypercholesterolemic individuals treated with atorvastatin.

Journal: Lipids in health and disease 20110101

Title: Reversible cerebral vasoconstriction syndrome in a patient taking citalopram and Hydroxycut: a case report.

Journal: Journal of medical case reports 20110101

Title: Simvastatin protects auditory hair cells from gentamicin-induced toxicity and activates Akt signaling in vitro.

Journal: BMC neuroscience 20110101

Title: Two cases of aspiration of calcium tablets.

Journal: Lung India : official organ of Indian Chest Society 20110101

Title: Mathematical prognostic biomarker models for treatment response and survival in epithelial ovarian cancer.

Journal: Cancer informatics 20110101

Title: Extended release niacin-laropiprant in patients with hypercholesterolemia or mixed dyslipidemias improves clinical parameters.

Journal: Clinical Medicine Insights. Cardiology 20110101

Title: Safety and efficacy of dronedarone in the treatment of atrial fibrillation/flutter.

Journal: Clinical Medicine Insights. Cardiology 20110101

Title: Low incidence of paradoxical reductions in HDL-C levels in dyslipidemic patients treated with fenofibrate alone or in combination with ezetimibe or ezetimibe/simvastatin.

Journal: Lipids in health and disease 20110101

Title: Malignant Cerebral Edema following CT Myelogram Using Isovue-M 300 Intrathecal Nonionic Water-Soluble Contrast: A Case Report.

Journal: Radiology research and practice 20110101

Title: Apolipoprotein A-I and A-I mimetic peptides: a role in atherosclerosis.

Journal: Journal of inflammation research 20110101

Title: Propofol infusion syndrome in a super morbidly obese patient (BMI = 75).

Journal: International journal of critical illness and injury science 20110101

Title: Chimeric anti-staphylococcal enterotoxin B antibodies and lovastatin act synergistically to provide in vivo protection against lethal doses of SEB.

Journal: PloS one 20110101

Title: Adaptation to statins restricts human tumour growth in Nude mice.

Journal: BMC cancer 20110101

Title: Achievement of specified low-density lipoprotein cholesterol, non-high-density lipoprotein cholesterol apolipoprotein B, and high-sensitivity C-reactive protein levels with ezetimibe/simvastatin or atorvastatin in metabolic syndrome patients with and without atherosclerotic vascular disease (from the VYMET study).

Journal: Journal of clinical lipidology 20110101

Title: Metachronous merkel cell carcinoma: a case report.

Journal: Case reports in dermatology 20110101

Title: Omega-3 polyunsaturated Fatty acids and heart rate variability.

Journal: Frontiers in physiology 20110101

Title: Single coronary artery with anomalous rising of the right coronary artery: a rare coronary anomaly diagnosed by 256-multidetector computed tomography.

Journal: Case reports in medicine 20110101

Title: Astragalus polysaccharides lowers plasma cholesterol through mechanisms distinct from statins.

Journal: PloS one 20110101

Title: Gut microbiota and sirtuins in obesity-related inflammation and bowel dysfunction.

Journal: Journal of translational medicine 20110101

Title: [Arginase, nitrates, and nitrites in the blood plasma and erythrocytes in hypertension and after therapy with lisinopril and simvastatin].

Journal: Izvestiia Akademii nauk. Seriia biologicheskaia 20110101

Title: Bioactive oat β-glucan reduces LDL cholesterol in Caucasians and non-Caucasians.

Journal: Nutrition journal 20110101

Title: Statins and prevention of infections: systematic review and meta-analysis of data from large randomised placebo controlled trials.

Journal: BMJ (Clinical research ed.) 20110101

Title: Regulation of suppressors of cytokine signaling as a therapeutic approach in autoimmune diseases, with an emphasis on multiple sclerosis.

Journal: Journal of signal transduction 20110101

Title: Different statins produce highly divergent changes in gene expression profiles of human hepatoma cells: a pilot study.

Journal: Acta biochimica Polonica 20110101

Title: Gene-drug interaction in stroke.

Journal: Stroke research and treatment 20110101

Title: Diabetes Health, Residence & Metabolism in Asians: the DHRMA study, research into foods from the Indian subcontinent - a blinded, randomised, placebo controlled trial.

Journal: BMC cardiovascular disorders 20110101

Title: Development of validated stability-indicating chromatographic method for the determination of fexofenadine hydrochloride and its related impurities in pharmaceutical tablets.

Journal: Chemistry Central journal 20110101

Title: Current state of cardiac rehabilitation in Germany: patient characteristics, risk factor management and control status, by education level.

Journal: Vascular health and risk management 20110101

Title: Induction of antibodies in rhesus macaques that recognize a fusion-intermediate conformation of HIV-1 gp41.

Journal: PloS one 20110101

Title: COPD/emphysema: The vascular story.

Journal: Pulmonary circulation 20110101

Title: Are prescribing doctors sensitive to the price that their patients have to pay in the Spanish National Health System?

Journal: BMC health services research 20110101

Title: Open-label phase 1b pilot study to assess the antiviral efficacy of simvastatin combined with sertraline in chronic hepatitis C patients.

Journal: Antiviral therapy 20110101

Title: Activation of type I interferon pathway in systemic lupus erythematosus: association with distinct clinical phenotypes.

Journal: Journal of biomedicine & biotechnology 20110101

Title: Small interfering RNA against transcription factor STAT6 leads to increased cholesterol synthesis in lung cancer cell lines.

Journal: PloS one 20110101

Title: Allopurinol causing drug rash with eosinophilia and systemic symptoms syndrome: a challenging diagnosis.

Journal: International journal of general medicine 20110101

Title: Combining antihypertensive and antihyperlipidemic agents - optimizing cardiovascular risk factor management.

Journal: Integrated blood pressure control 20110101

Title: Treatment with statins and peripheral neuropathy: results of 36-months a prospective clinical and neurophysiological follow-up.

Journal: Neuro endocrinology letters 20110101

Title: Nanosuspension: An approach to enhance solubility of drugs.

Journal: Journal of advanced pharmaceutical technology & research 20110101

Title: Price, familiarity, and availability determine the choice of drug - a population-based survey five years after generic substitution was introduced in Finland.

Journal: BMC clinical pharmacology 20110101

Title: Mild and moderate pre-dialysis chronic kidney disease is associated with increased coronary artery calcium.

Journal: Vascular health and risk management 20110101

Title: Imatinib mesylate: past successes and future challenges in the treatment of gastrointestinal stromal tumors.

Journal: Clinical Medicine Insights. Oncology 20110101

Title: Medical angioplasty - hope and expectations: an optimistic overview.

Journal: Journal of family & community medicine 20110101

Title: A cluster randomised trial of educational messages to improve the primary care of diabetes.

Journal: Implementation science : IS 20110101

Title: The polypill in the primary prevention of cardiovascular disease: cost-effectiveness in the Dutch population.

Journal: BMJ open 20110101

Title: Peroxisome Proliferator-Activated Receptor-α Activation Decreases Mean Arterial Pressure, Plasma Interleukin-6, and COX-2 While Increasing Renal CYP4A Expression in an Acute Model of DOCA-Salt Hypertension.

Journal: PPAR research 20110101

Title: Strategies for reducing or preventing the generation of oxidative stress.

Journal: Oxidative medicine and cellular longevity 20110101

Title: Protective Effects of Simvastatin, a Lipid Lowering Agent, against Oxidative Damage in Experimental Diabetic Rats.

Journal: Journal of lipids 20110101

Title: Cholesterol, C-Reactive Protein, and Periodontitis: HMG-CoA-Reductase Inhibitors (Statins) as Effect Modifiers.

Journal: ISRN dentistry 20110101

Title: Statin-associated muscular and renal adverse events: data mining of the public version of the FDA adverse event reporting system.

Journal: PloS one 20110101

Title: Preventing Cardio-renal Syndrome Rather than Treating It: Could Statins Play A Role?

Journal: The open cardiovascular medicine journal 20110101

Title: Differential effects of pravastatin and simvastatin on the growth of tumor cells from different organ sites.

Journal: PloS one 20110101

Title: Nanotube action between human mesothelial cells reveals novel aspects of inflammatory responses.

Journal: PloS one 20110101

Title: The pivotal role of airway smooth muscle in asthma pathophysiology.

Journal: Journal of allergy 20110101

Title: [Effect of cardiovascular drugs on vasodilating endothelial function in animals with experimental deficiency of sex hormones].

Journal: Eksperimental'naia i klinicheskaia farmakologiia 20110101

Title: Critical appraisal of ticagrelor in the management of acute coronary syndrome.

Journal: Therapeutics and clinical risk management 20110101

Title: Preparation, characterization, and in vivo evaluation of a self-nanoemulsifying drug delivery system (SNEDDS) loaded with morin-phospholipid complex.

Journal: International journal of nanomedicine 20110101

Title: Efficacy and safety of gonadotropin-releasing hormone agonists used in the treatment of prostate cancer.

Journal: Drug, healthcare and patient safety 20110101

Title: Two-way pharmacokinetic interaction studies between saxagliptin and cytochrome P450 substrates or inhibitors: simvastatin, diltiazem extended-release, and ketoconazole.

Journal: Clinical pharmacology : advances and applications 20110101

Title: Pathway-Wide Association Study Implicates Multiple Sterol Transport and Metabolism Genes in HDL Cholesterol Regulation.

Journal: Frontiers in genetics 20110101

Title: Optimal management of peripheral arterial disease for the non-specialist.

Journal: The Ulster medical journal 20110101

Title: Effects of simvastatin on the pharmacokinetics of diltiazem and its main metabolite, desacetyldiltiazem, after oral and intravenous administration in rats: possible role of P-glycoprotein and CYP3A4 inhibition by simvastatin.

Journal: Pharmacological reports : PR 20110101

Title: Inflammatory Animal Model for Parkinson's Disease: The Intranigral Injection of LPS Induced the Inflammatory Process along with the Selective Degeneration of Nigrostriatal Dopaminergic Neurons.

Journal: ISRN neurology 20110101

Title: No consensus on definition criteria for stroke registry common data elements.

Journal: Cerebrovascular diseases extra 20110101

Title: Statin Hepatotoxicity: Is it a Real Concern?

Journal: Heart views : the official journal of the Gulf Heart Association 20110101

Title: Statins: past and present.

Journal: Heart views : the official journal of the Gulf Heart Association 20110101

Title: Adrenal Failure due to Adrenal Metastasis of Lung Cancer: A Case Report.

Journal: Case reports in oncological medicine 20110101

Title: Simvastatin-induced dermatomyositis in a 50-year-old man.

Journal: BMJ case reports 20110101

Title: My legs are getting old: sinvastatin-induced polyneuropathy.

Journal: BMJ case reports 20110101

Title: Rhabdomyolysis with simvastatin.

Journal: BMJ case reports 20110101

Title: Effects of simvastatin on markers of inflammation, oxidative stress and endothelial cell apoptosis in patients on chronic hemodialysis.

Journal: Journal of atherosclerosis and thrombosis 20101226

Title: Garlic extract induces intestinal P-glycoprotein, but exhibits no effect on intestinal and hepatic CYP3A4 in humans.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20101223

Title: Getting better value from the NHS drug budget.

Journal: BMJ (Clinical research ed.) 20101217

Title: Statins inhibited erythropoietin-induced proliferation of rat vascular smooth muscle cells.

Journal: European journal of pharmacology 20101215

Title: Simvastatin attenuates cardiopulmonary bypass-induced myocardial inflammatory injury in rats by activating peroxisome proliferator-activated receptor γ.

Journal: European journal of pharmacology 20101215

Title: Laminar shear stress prevents simvastatin-induced adhesion molecule expression in cytokine activated endothelial cells.

Journal: European journal of pharmacology 20101215

Title: Involvement of oxidative stress in simvastatin-induced apoptosis of murine CT26 colon carcinoma cells.

Journal: Toxicology letters 20101215

Title: Statins for multiple sclerosis.

Journal: The Cochrane database of systematic reviews 20101208

Title: Effects of Satureja khuzestanica on Serum Glucose, Lipids and Markers of Oxidative Stress in Patients with Type 2 Diabetes Mellitus: A Double-Blind Randomized Controlled Trial.

Journal: Evidence-based complementary and alternative medicine : eCAM 20101201

Title: Growth-dependent changes in the contribution of carbon monoxide to arteriolar function.

Journal: Journal of vascular research 20101201

Title: Atherosclerosis regression study in rabbits upon olive pomace polar lipid extract administration.

Journal: Nutrition, metabolism, and cardiovascular diseases : NMCD 20101201

Title: Molecular imaging in atherosclerosis.

Journal: European journal of nuclear medicine and molecular imaging 20101201

Title: Simvastatin overcomes the resistance to serum withdrawal-induced apoptosis of lymphocytes from Alzheimer's disease patients.

Journal: Cellular and molecular life sciences : CMLS 20101201

Title: Dipyridamole with low-dose aspirin augments the infarct size-limiting effects of simvastatin.

Journal: Cardiovascular drugs and therapy 20101201

Title: Optimized microemulsions and solid microemulsion systems of simvastatin: characterization and in vivo evaluation.

Journal: Journal of pharmaceutical sciences 20101201

Title: [Should the treatment of diabetic dyslipidemia be modified after the Action to Control Cardiovascular Risk in Diabetes Lipid study?].

Journal: Endocrinologia y nutricion : organo de la Sociedad Espanola de Endocrinologia y Nutricion 20101201

Title: Lipophilic statins prevent matrix metalloproteinase-mediated cartilage collagen breakdown by inhibiting protein geranylgeranylation.

Journal: Annals of the rheumatic diseases 20101201

Title: Hypercholesterolemia in rats impairs the cholinergic system and leads to memory deficits.

Journal: Molecular and cellular neurosciences 20101201

Title: Statins and pancreatic cancer risk: a nested case-control study.

Journal: Cancer causes & control : CCC 20101201

Title: Effects of simvastatin and 6-hydroxydopamine on histaminergic H1 receptor binding density in rat brains.

Journal: Progress in neuro-psychopharmacology & biological psychiatry 20101201

Title: Effect of ezetimibe-simvastatine over endothelial dysfunction in dyslipidemic patients: assessment by 13N-ammonia positron emission tomography.

Journal: Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology 20101201

Title: Rates and determinants of coronary and abdominal aortic artery calcium progression in the Veterans Affairs Diabetes Trial (VADT).

Journal: Diabetes care 20101201

Title: Efficacy of simvastatin in reducing aortic dilatation in mouse models of abdominal aortic aneurysm.

Journal: Cardiovascular drugs and therapy 20101201

Title: In vitro evaluation of inhibitory effects of antidiabetic and antihyperlipidemic drugs on human carboxylesterase activities.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20101201

Title: Statins inhibit growth of human theca-interstitial cells in PCOS and non-PCOS tissues independently of cholesterol availability.

Journal: The Journal of clinical endocrinology and metabolism 20101201

Title: Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20101201

Title: A predictive ligand-based Bayesian model for human drug-induced liver injury.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20101201

Title: Metformin treatment may increase omentin-1 levels in women with polycystic ovary syndrome.

Journal: Diabetes 20101201

Title: Engineered polyketide biosynthesis and biocatalysis in Escherichia coli.

Journal: Applied microbiology and biotechnology 20101201

Title: Efficient four-drug cocktail therapy targeting amyloid-β peptide for Alzheimer's disease.

Journal: Journal of neuroscience research 20101201

Title: IL-2 costimulation enables statin-mediated activation of human NK cells, preferentially through a mechanism involving CD56+ dendritic cells.

Journal: Cancer research 20101201

Title: Statins alter intracellular calcium homeostasis in malignant hyperthermia susceptible individuals.

Journal: Cardiovascular therapeutics 20101201

Title: Evaluation and discrimination of simvastatin-induced structural alterations in proteins of different rat tissues by FTIR spectroscopy and neural network analysis.

Journal: The Analyst 20101201

Title: Rhabdomyolysis in a patient receiving high-dose simvastatin after the induction of therapeutic hypothermia.

Journal: The Annals of pharmacotherapy 20101201

Title: Simvastatin inhibits goblet cell hyperplasia and lung arginase in a mouse model of allergic asthma: a novel treatment for airway remodeling?

Journal: Translational research : the journal of laboratory and clinical medicine 20101201

Title: Simvastatin prevents ERK activation in myocardial hypertrophy of spontaneously hypertensive rats.

Journal: Scandinavian cardiovascular journal : SCJ 20101201

Title: Impact of baseline severity of aortic valve stenosis on effect of intensive lipid lowering therapy (from the SEAS study).

Journal: The American journal of cardiology 20101201

Title: Probable interaction between warfarin and bee pollen.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20101201

Title: Statin prevents chondrocyte aging and degeneration of articular cartilage in osteoarthritis (OA).

Journal: Aging 20101201

Title: Assessment of the quality of simvastatin capsules from compounding pharmacies.

Journal: Revista de saude publica 20101201

Title: [88 years old woman with acute muscular weakness and diffuse muscular pain: have you thought about the drugs?].

Journal: Praxis 20101201

Title: Comparing policies to enhance prescribing efficiency in Europe through increasing generic utilization: changes seen and global implications.

Journal: Expert review of pharmacoeconomics & outcomes research 20101201

Title: Efficacy and safety of long-term ezetimibe/simvastatin treatment in patients with familial hypercholesterolemia.

Journal: International angiology : a journal of the International Union of Angiology 20101201

Title: [Complete atrioventricular block due to hyperkalemia caused by rhabdomyolysis during treatment with statin].

Journal: Kardiologia polska 20101201

Title: Simvastatin prevents inflammation-induced aortic stiffening and endothelial dysfunction.

Journal: British journal of clinical pharmacology 20101201

Title: [Effects of simvastatin on plasma SOD, MDA and 8-iso-PGF2α in patients with stable angina].

Journal: Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20101201

Title: Effect of statin on the reference segments after bare-metal stent implantation.

Journal: The Korean journal of internal medicine 20101201

Title: Usual dose of simvastatin does not inhibit plaque progression and lumen loss at the peri-stent reference segments after bare-metal stent implantation: a serial intravascular ultrasound analysis.

Journal: The Korean journal of internal medicine 20101201

Title: Effects of simvastatin on the function of dendritic cells in patients with rheumatic arthritis.

Journal: Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20101201

Title: Cardiovascular diseases. Introduction.

Journal: Atherosclerosis. Supplements 20101201

Title: Pitavastatin - results from phase III & IV.

Journal: Atherosclerosis. Supplements 20101201

Title: Pitavastatin - from clinical trials to clinical practice.

Journal: Atherosclerosis. Supplements 20101201

Title: Different effects of simvastatin on ex vivo monocyte cytokine release in patients with hypercholesterolemia and impaired glucose tolerance.

Journal: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20101201

Title: A retrospective study on the efficacy of a ten-milligram dosage of atorvastatin for treatment of hypercholesterolemia in type 2 diabetes mellitus patients.

Journal: Korean diabetes journal 20101201

Title: Effects of statins on the epicardial fat thickness in patients with coronary artery stenosis underwent percutaneous coronary intervention: comparison of atorvastatin with simvastatin/ezetimibe.

Journal: Journal of cardiovascular ultrasound 20101201

Title: Simvastatin, sildenafil and their combination in monocrotaline induced pulmonary arterial hypertension.

Journal: Korean circulation journal 20101201

Title: Lipid lowering efficacy between morning and evening simvastatin treatment: a randomized double-blind study.

Journal: Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20101201

Title: Hemodynamic alterations in cirrhosis and portal hypertension.

Journal: The Korean journal of hepatology 20101201

Title: [Effect of simvastatin on the function of MG63 cell line].

Journal: Shanghai kou qiang yi xue = Shanghai journal of stomatology 20101201

Title: Pharmacological neuroprotection after perinatal hypoxic-ischemic brain injury.

Journal: Current neuropharmacology 20101201

Title: Drug development for Alzheimer's disease: recent progress.

Journal: Experimental neurobiology 20101201

Title: Successful drug development despite adverse preclinical findings part 2: examples.

Journal: Journal of toxicologic pathology 20101201

Title: Effect of atorvastatin in patients with chronic heart failure - insights from randomized clinical trials.

Journal: Archives of medical science : AMS 20101201

Title: Structural insights into substrate specificity in variants of N-acetylneuraminic Acid lyase produced by directed evolution.

Journal: Journal of molecular biology 20101119

Title: ACP Journal Club. Intensifying glucose control and adding fenofibrate to simvastatin each reduced progression of retinopathy in type 2 diabetes.

Journal: Annals of internal medicine 20101116

Title: Preparation and evaluation of nicotinic acid sustained-release pellets combined with immediate release simvastatin.

Journal: International journal of pharmaceutics 20101115

Title: Simvastatin interferes with process outgrowth and branching of oligodendrocytes.

Journal: Journal of neuroscience research 20101115

Title: Efficacy and safety of more intensive lowering of LDL cholesterol: a meta-analysis of data from 170,000 participants in 26 randomised trials.

Journal: Lancet (London, England) 20101113

Title: Intensive lowering of LDL cholesterol with 80 mg versus 20 mg simvastatin daily in 12,064 survivors of myocardial infarction: a double-blind randomised trial.

Journal: Lancet (London, England) 20101113

Title: Is intensive LDL-cholesterol lowering beneficial and safe?

Journal: Lancet (London, England) 20101113

Title: Synergistic benefits of erythropoietin and simvastatin after traumatic brain injury.

Journal: Brain research 20101111

Title: A hydroxymethylglutaryl coenzyme A reductase inhibitor improves endothelial function within 7 days in patients with chronic hemodialysis.

Journal: International journal of cardiology 20101105

Title: Effects of metformin plus simvastatin on polycystic ovary syndrome: a prospective, randomized, double-blind, placebo-controlled study.

Journal: Fertility and sterility 20101101

Title: Simvastatin attenuates hypomyelination induced by hypoxia-ischemia in neonatal rats.

Journal: Neurological research 20101101

Title: Simvastatin and purine analogs have a synergic effect on apoptosis of chronic lymphocytic leukemia cells.

Journal: Annals of hematology 20101101

Title: Prevalence and overlap of different lipid abnormalities in statin-treated patients at high cardiovascular risk in clinical practice in Germany.

Journal: Clinical research in cardiology : official journal of the German Cardiac Society 20101101

Title: Preparation and characterization of solid dispersion of simvastatin.

Journal: Drug development and industrial pharmacy 20101101

Title: Simvastatin induces osteogenic differentiation of murine embryonic stem cells.

Journal: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20101101

Title: Modulation of the Rho/ROCK pathway in heart and lung after thorax irradiation reveals targets to improve normal tissue toxicity.

Journal: Current drug targets 20101101

Title: Plasma apolipoprotein M responses to statin and fibrate administration in type 2 diabetes mellitus.

Journal: Atherosclerosis 20101101

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: Simvastatin inhibits cell growth and induces apoptosis and G0/G1 cell cycle arrest in hepatic cancer cells.

Journal: International journal of molecular medicine 20101101

Title: Potential therapeutic uses for ezetimibe beyond lowering LDL-c to decrease cardiovascular events.

Journal: Diabetes, obesity & metabolism 20101101

Title: Long-term efficacy and safety of ezetimibe/simvastatin coadministered with extended-release niacin in hyperlipidaemic patients with diabetes or metabolic syndrome.

Journal: Diabetes, obesity & metabolism 20101101

Title: Rhabdomyolysis in a patient receiving ranolazine and simvastatin.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20101101

Title: [On the current debate on lowering LDL cholesterol with ezetimibe].

Journal: Deutsche medizinische Wochenschrift (1946) 20101101

Title: [On the current debate on lowering LDL cholesterol with ezetimibe].

Journal: Deutsche medizinische Wochenschrift (1946) 20101101

Title: Safety and efficacy of ezetimibe/simvastatin combination versus atorvastatin alone in adults ≥65 years of age with hypercholesterolemia and with or at moderately high/high risk for coronary heart disease (the VYTELD study).

Journal: The American journal of cardiology 20101101

Title: Radiation recall with anticancer agents.

Journal: The oncologist 20101101

Title: Effects of simvastatin on relapse and remodeling of periodontal tissues after tooth movement in rats.

Journal: American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics 20101101

Title: Ezetimibe as a potential treatment for dyslipidemia associated with chronic renal failure and renal transplant.

Journal: Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia 20101101

Title: Effect of simvastatin on collagen I deposition in non-infarcted myocardium: role of NF-κB and osteopontin.

Journal: Canadian journal of physiology and pharmacology 20101101

Title: Emphasizing the burden of proof: The American College of Cardiology 2008 Expert Panel Comments on the ENHANCE Trial.

Journal: Circulation. Cardiovascular quality and outcomes 20101101

Title: Study of Heart and Renal Protection (SHARP): randomized trial to assess the effects of lowering low-density lipoprotein cholesterol among 9,438 patients with chronic kidney disease.

Journal: American heart journal 20101101

Title: The effect of simvastatin on lymphocyte secretory function in patients with impaired fasting glucose.

Journal: Journal of cardiovascular pharmacology 20101101

Title: [Effects of lipid-modulation and antiplatelet treatment on the endothelial lipase expression].

Journal: Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue 20101101

Title: Human health risk assessment of pharmaceuticals in water: issues and challenges ahead.

Journal: International journal of environmental research and public health 20101101

Title: Diabetes & coronary heart disease: current perspectives.

Journal: The Indian journal of medical research 20101101

Title: Niacin extended release (ER)/simvastatin (Simcor®): a guide to its use in lipid regulation.

Journal: Drugs in R&D 20101101

Title: [The effect of simvastatin on alveolar epithelial cells in cigarette smoking-induced emphysema].

Journal: Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases 20101101

Title: Effects of low-dose simvastatin on the distribution of plasma cholesterol and oxidized low-density lipoprotein in three ultra-centrifugally separated low-density lipoprotein subfractions: 12- month, open-label trial.

Journal: Journal of atherosclerosis and thrombosis 20101027

Title: Simvastatin enhances immune responses to Aβ vaccination and attenuates vaccination-induced behavioral alterations.

Journal: Brain research 20101014

Title: On the inhibitor effects of bergamot juice flavonoids binding to the 3-hydroxy-3-methylglutaryl-CoA reductase (HMGR) enzyme.

Journal: Journal of agricultural and food chemistry 20101013

Title: The effect of simvastatin on the survival of ischaemic skin flap: an experimental study in rats.

Journal: Journal of plastic, reconstructive & aesthetic surgery : JPRAS 20101001

Title: Effects of concomitant therapy with diltiazem on the lipid responses to simvastatin in Chinese subjects.

Journal: Journal of clinical pharmacology 20101001

Title: Combination of sildenafil and simvastatin ameliorates monocrotaline-induced pulmonary hypertension in rats.

Journal: Pulmonary pharmacology & therapeutics 20101001

Title: Coadministration of dalcetrapib with pravastatin, rosuvastatin, or simvastatin: no clinically relevant drug-drug interactions.

Journal: Journal of clinical pharmacology 20101001

Title: Pleiotropic effects of atorvastatin and fenofibrate in metabolic syndrome and different types of pre-diabetes.

Journal: Diabetes care 20101001

Title: Hepatotoxicity associated with metformin therapy in treatment of type 2 diabetes mellitus with nonalcoholic fatty liver disease.

Journal: The Annals of pharmacotherapy 20101001

Title: Patients' preference for olanzapine orodispersible tablet compared with conventional oral tablet in a multinational, randomized, crossover study.

Journal: The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry 20101001

Title: Altered cholesterol homeostasis contributes to enhanced excitotoxicity in Huntington's disease.

Journal: Journal of neurochemistry 20101001

Title: Simvastatin reduces sympathetic activity in men with hypertension and hypercholesterolemia.

Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20101001

Title: Comparison of the post-embolization effects of tissue-plasminogen activator and simvastatin on neurological outcome in a clinically relevant rat model of acute ischemic stroke.

Journal: Brain research 20101001

Title: Change in serum lipids after acute coronary syndromes: secondary analysis of SPACE ROCKET study data and a comparative literature review.

Journal: Clinical chemistry 20101001

Title: Compromized geranylgeranylation of RhoA and Rac1 in mevalonate kinase deficiency.

Journal: Journal of inherited metabolic disease 20101001

Title: Cost-effectiveness of statin therapy for vascular event prevention in adults with elevated C-reactive protein: implications of JUPITER.

Journal: Current medical research and opinion 20101001

Title: Simvastatin inhibited cardiac hypertrophy and fibrosis in apolipoprotein E-deficient mice fed a 'Western-style diet' by increasing PPAR α and γ expression and reducing TC, MMP-9, and Cat S levels.

Journal: Acta pharmacologica Sinica 20101001

Title: Ezetimibe in diabetes: more than cholesterol lowering?

Journal: Current medical research and opinion 20101001

Title: Hypotension and bradycardia associated with concomitant tizanidine and lisinopril therapy.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20101001

Title: Simvastatin in the treatment of asthma: lack of steroid-sparing effect.

Journal: Thorax 20101001

Title: Effect of Qingre Quyu Granule (清热祛瘀颗粒) on stabilizing plaques in the brachiocephalic artery of apolipoprotein E deficient mice.

Journal: Chinese journal of integrative medicine 20101001

Title: Effects of combined ezetimibe and simvastatin therapy as compared with simvastatin alone in patients with type 2 diabetes: a prospective randomized double-blind clinical trial: comment on Ruggenenti et al.

Journal: Diabetes care 20101001

Title: ApoA-1 in diabetes: damaged goods.

Journal: Diabetes 20101001

Title: Development and validation of spectrophotometeric method for simultaneous determination of simvastatin and ezetimibe in tablet formulations.

Journal: Pakistan journal of pharmaceutical sciences 20101001

Title: Statins enhance the anti-inflammatory effects of inhaled corticosteroids in asthmatic patients through increased induction of indoleamine 2, 3-dioxygenase.

Journal: The Journal of allergy and clinical immunology 20101001

Title: [High-dose statin therapy for high-risk patients].

Journal: Herz 20101001

Title: Effects of low-dose of niacin associated to simvastatin in the treatment of mixed dyslipidemia Salgad.

Journal: Minerva cardioangiologica 20101001

Title: Dengue virus ensures its fusion in late endosomes using compartment-specific lipids.

Journal: PLoS pathogens 20101001

Title: Protecting against ischemia-reperfusion injury: antiplatelet drugs, statins, and their potential interactions.

Journal: Annals of the New York Academy of Sciences 20101001

Title: Heterozygous familial hypercholesterolemia case study.

Journal: Journal of the American Academy of Nurse Practitioners 20101001

Title: Lipoprotein-associated phospholipase A₂ activity and mass in relation to vascular disease and nonvascular mortality.

Journal: Journal of internal medicine 20101001

Title: [Effects of simvastatin on the proliferation of HepG2 cells].

Journal: Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20101001

Title: [Randomized comparative study on the lipid lowering effects of Zhikang Granule and simvastatin].

Journal: Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20101001

Title: [Simvastatin suppress lipopolysaccharides induced upregulation of lipoprotein associated phospholipase A(2) expression in macrophages via inactivation of p38MAPK pathway].

Journal: Zhonghua xin xue guan bing za zhi 20101001

Title: By the way, doctor. I've been advised not to take my statin drug, simvastatin, with grapefruit juice. But is it safe to take the medication at night and then drink grapefruit juice in the morning?

Journal: Harvard women's health watch 20101001

Title: On call. I've been taking Zocor since my heart attack in 2006. My cholesterol count has come way down, and I haven't had any heart problems. In the past few months, however, I've had some muscle aches. My blood tests don't show any muscle damage, but my doctor says Zocor may still be causing the problem. He wants me to stop Zocor for a while, but I'm worried about my heart. Is it safe for me to stop?

Journal: Harvard men's health watch 20101001

Title: Safety of simvastatin and goal attainment for low-density lipoprotein cholesterol in sultan qaboos university hospital.

Journal: Oman medical journal 20101001

Title: Are we getting to lipid targets in real life?

Journal: Archives of medical science : AMS 20101001

Title: Changes in attainment of lipid goals by general practitioners and specialists in patients at high cardiovascular risk in Hungary during 2004-2008.

Journal: Archives of medical science : AMS 20101001

Title: Managing residual risk in patients receiving statin therapy.

Journal: The Medical journal of Australia 20100920

Title: Simvastatin-dependent up-regulation of heme oxygenase-1 via mRNA stabilization in human endothelial cells.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20100911

Title: Attenuation of astrogliosis and modulation of endothelial growth factor receptor in lipid rafts by simvastatin after traumatic brain injury.

Journal: Journal of neurosurgery 20100901

Title: Simvastatin reduces pressor response to centrally administered angiotensin II.

Journal: American journal of hypertension 20100901

Title: Do statins beneficially or adversely affect glucose homeostasis?

Journal: Current vascular pharmacology 20100901

Title: Are treatment targets for hypercholesterolemia evidence based? Systematic review and meta-analysis of randomised controlled trials.

Journal: Archives of disease in childhood 20100901

Title: Ultrasound-enhanced drug transport and distribution in the brain.

Journal: AAPS PharmSciTech 20100901

Title: Reduction of endoplasmic reticulum stress--a novel mechanism of action of statins in the protection against atherosclerosis.

Journal: Atherosclerosis 20100901

Title: Profiling induction of cytochrome p450 enzyme activity by statins using a new liquid chromatography-tandem mass spectrometry cocktail assay in human hepatocytes.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20100901

Title: Improvement of retinal vascular injury in diabetic rats by statins is associated with the inhibition of mitochondrial reactive oxygen species pathway mediated by peroxisome proliferator-activated receptor gamma coactivator 1alpha.

Journal: Diabetes 20100901

Title: Effects of combined ezetimibe and simvastatin therapy as compared with simvastatin alone in patients with type 2 diabetes: a prospective randomized double-blind clinical trial.

Journal: Diabetes care 20100901

Title: The effects of fenofibric acid alone and with statins on the prevalence of metabolic syndrome and its diagnostic components in patients with mixed dyslipidemia.

Journal: Diabetes care 20100901

Title: Biosynthesis of lovastatin and related metabolites formed by fungal iterative PKS enzymes.

Journal: Biopolymers 20100901

Title: Lack of neuroprotective effects of simvastatin and minocycline in a model of cervical spinal cord injury.

Journal: Experimental neurology 20100901

Title: Cytotoxicity of atorvastatin and simvastatin on primary rainbow trout (Oncorhynchus mykiss) hepatocytes.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20100901

Title: Rosuvastatin, identified from a zebrafish chemical genetic screen for antiangiogenic compounds, suppresses the growth of prostate cancer.

Journal: European urology 20100901

Title: Simvastatin ameliorates rat cerebrovascular remodeling during hypertension via inhibition of volume-regulated chloride channel.

Journal: Hypertension (Dallas, Tex. : 1979) 20100901

Title: Effect of simvastatin on burn-induced alterations in tissue specific glucose metabolism: implications for burn associated insulin resistance.

Journal: International journal of molecular medicine 20100901

Title: High-density lipoprotein induces proliferation and migration of human prostate androgen-independent cancer cells by an ABCA1-dependent mechanism.

Journal: Molecular cancer research : MCR 20100901

Title: On the combined effect of statins and lycopene on cytokine production by human peripheral blood cells.

Journal: Heart and vessels 20100901

Title: Impact of restricted reimbursement on the use of statins in Finland: a register-based study.

Journal: Medical care 20100901

Title: Effectiveness, safety and cost of drug substitution in hypertension.

Journal: British journal of clinical pharmacology 20100901

Title: General practitioners' views and experiences of over-the-counter simvastatin in Scotland.

Journal: British journal of clinical pharmacology 20100901

Title: Simvastatin inhibits aortic valve calcification in hypercholesterolemic rabbits.

Journal: Interactive cardiovascular and thoracic surgery 20100901

Title: Lack of clopidogrel-statin interaction in patients undergoing coronary stent implantation.

Journal: Arquivos brasileiros de cardiologia 20100901

Title: Results of a safety initiative for patients on concomitant amiodarone and simvastatin therapy in a Veterans Affairs medical center.

Journal: Journal of managed care pharmacy : JMCP 20100901

Title: Effects of drug interactions on biotransformation and antiplatelet effect of clopidogrel in vitro.

Journal: British journal of pharmacology 20100901

Title: Disparate effects of atorvastatin compared with simvastatin on C-reactive protein concentrations in patients with type 2 diabetes.

Journal: Diabetes care 20100901

Title: The pathogenetic features of cerebral cavernous malformations: a comprehensive review with therapeutic implications.

Journal: Neurosurgical focus 20100901

Title: Persistence with statins and onset of rheumatoid arthritis: a population-based cohort study.

Journal: PLoS medicine 20100901

Title: Effects of lipid-lowering drugs on reverse cholesterol transport gene expressions in peripheral blood mononuclear and HepG2 cells.

Journal: Pharmacogenomics 20100901

Title: 3ST-POL trial: standards of statin use in Poland in the context of the European Society of Cardiology guidelines.

Journal: Polskie Archiwum Medycyny Wewnetrznej 20100901

Title: Literature mining for the discovery of hidden connections between drugs, genes and diseases.

Journal: PLoS computational biology 20100901

Title: [Effect of electroacupuncture on lipid metabolism in metabolic syndrome].

Journal: Zhongguo zhen jiu = Chinese acupuncture & moxibustion 20100901

Title: [Effects of simvastatin on expression of CTGF and α-SMA in renal tubulointerstitium of rats with diabetic nephropathy].

Journal: Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences 20100901

Title: [Effect of simvastatin on inducing endothelial progenitor cells homing and promoting bone defect repair].

Journal: Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery 20100901

Title: Ultrasound diagnosis of bilateral quadriceps tendon rupture after statin use.

Journal: The western journal of emergency medicine 20100901

Title: Severe visual loss secondary to central serous chorioretinopathy following prolonged immune suppression with oral prednisolone.

Journal: JRSM short reports 20100901

Title: [High dose of simvastatin to minimize the risk of myopathy?].

Journal: Medizinische Monatsschrift fur Pharmazeuten 20100901

Title: Acute hepatitis associated with the use of levofloxacin.

Journal: Clinical therapeutics 20100901

Title: Antiepileptic drug interactions - principles and clinical implications.

Journal: Current neuropharmacology 20100901

Title: Effects of combination lipid therapy in the management of patients with type 2 diabetes mellitus in the Action to Control Cardiovascular Risk in Diabetes (ACCORD) trial.

Journal: Circulation 20100824

Title: Combination lipid therapy in type 2 diabetes.

Journal: The New England journal of medicine 20100812

Title: Combination lipid therapy in type 2 diabetes.

Journal: The New England journal of medicine 20100812

Title: Statins for the treatment of dementia.

Journal: The Cochrane database of systematic reviews 20100804

Title: Simvastatin attenuates hepatic sensitization to lipopolysaccharide after partial hepatectomy.

Journal: The Journal of surgical research 20100801

Title: Small-animal SPECT and SPECT/CT: application in cardiovascular research.

Journal: European journal of nuclear medicine and molecular imaging 20100801

Title: Lipid and C-reactive protein levels, cardiovascular disease risk factors and simvastatin treatment in Brazilian individuals.

Journal: Inflammation 20100801

Title: Determination of simvastatin-induced changes in bone composition and structure by Fourier transform infrared spectroscopy in rat animal model.

Journal: Journal of pharmaceutical and biomedical analysis 20100801

Title: Role of matrix metalloproteinase-9 in the development of diabetic retinopathy and its regulation by H-Ras.

Journal: Investigative ophthalmology & visual science 20100801

Title: Definitions and incidence of cardiac syndrome X: review and analysis of clinical data.

Journal: Clinical research in cardiology : official journal of the German Cardiac Society 20100801

Title: Simvastatin induces Foxp3+ T regulatory cells by modulation of transforming growth factor-beta signal transduction.

Journal: Immunology 20100801

Title: Soluble fibre (Plantago ovata husk) reduces plasma low-density lipoprotein (LDL) cholesterol, triglycerides, insulin, oxidised LDL and systolic blood pressure in hypercholesterolaemic patients: A randomised trial.

Journal: Atherosclerosis 20100801

Title: Colorimetric determination of simvastatin and lovastatin in pure form and in pharmaceutical formulations.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20100801

Title: Implications of the ACCORD lipid study: perspective from the Residual Risk Reduction Initiative (R(3)i).

Journal: Current medical research and opinion 20100801

Title: Immune regulatory effects of simvastatin on regulatory T cell-mediated tumour immune tolerance.

Journal: Clinical and experimental immunology 20100801

Title: Management of hypertriglyceridemia in the diabetic patient.

Journal: Current diabetes reports 20100801

Title: Osteopontin is a new target molecule for ovarian clear cell carcinoma therapy.

Journal: Cancer science 20100801

Title: Polypill: lights and shadows.

Journal: Current hypertension reports 20100801

Title: Do structural differences in statins correlate with clinical efficacy?

Journal: Current opinion in lipidology 20100801

Title: The tolerability and efficacy of low-dose simvastatin in statin-intolerant patients.

Journal: European journal of internal medicine 20100801

Title: Fibrates: no ACCORD on their use in the treatment of dyslipidaemia.

Journal: Current opinion in lipidology 20100801

Title: Erythema multiforme photoinduced by statins.

Journal: Photodermatology, photoimmunology & photomedicine 20100801

Title: Effects of fungal statins on high-glucose-induced mouse mesangial cell hypocontractility may involve filamentous actin, t-complex polypeptide 1 subunit beta, and glucose regulated protein 78.

Journal: Translational research : the journal of laboratory and clinical medicine 20100801

Title: Simvastatin attenuates testicular injury induced by torsion-detorsion.

Journal: The Journal of urology 20100801

Title: Comparison of atorvastatin 80 mg/day versus simvastatin 20 to 40 mg/day on frequency of cardiovascular events late (five years) after acute myocardial infarction (from the Incremental Decrease in End Points through Aggressive Lipid Lowering [IDEAL] trial).

Journal: The American journal of cardiology 20100801

Title: Non-concurrent dosing attenuates the pharmacokinetic interaction between amlodipine and simvastatin.

Journal: International journal of clinical pharmacology and therapeutics 20100801

Title: Clinical and economic outcomes in patients switched to simvastatin in a community-based family medicine practice.

Journal: International journal of clinical practice 20100801

Title: Simvastatin effects on portal-systemic collaterals of portal hypertensive rats.

Journal: Journal of gastroenterology and hepatology 20100801

Title: Cost-effectiveness of interventions to prevent and control diabetes mellitus: a systematic review.

Journal: Diabetes care 20100801

Title: Pitavastatin for the treatment of primary hyperlipidemia and mixed dyslipidemia.

Journal: Expert review of cardiovascular therapy 20100801

Title: Incomparable effectiveness--apples to apples?

Journal: Mayo Clinic proceedings 20100801

Title: Using search engine query data to track pharmaceutical utilization: a study of statins.

Journal: The American journal of managed care 20100801

Title: ANCA-positive vasculitis associated with simvastatin/ezetimibe: expanding the spectrum of statin-induced autoimmunity?

Journal: International journal of rheumatic diseases 20100801

Title: Therapeutic effect of statin on aortic stenosis: a review with meta-analysis.

Journal: Journal of clinical pharmacy and therapeutics 20100801

Title: An introduction to biomolecular graphics.

Journal: PLoS computational biology 20100801

Title: [The effect of fufang zhenzhu tiaozhi capsule on lipid metabolism in atherosclerotic rabbits].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20100801

Title: Complex atheromatosis of the aortic arch in cerebral infarction.

Journal: Current cardiology reviews 20100801

Title: Angiogenesis, neurogenesis and neuroplasticity in ischemic stroke.

Journal: Current cardiology reviews 20100801

Title: Is there Emergence of Clinical HBV Resistance Under Long-Term HBV Combination Therapy? A Challenging Case Report.

Journal: Viruses 20100801

Title: Don't mess with the DSMB.

Journal: The New England journal of medicine 20100729

Title: Flow cessation triggers endothelial dysfunction during organ cold storage conditions: strategies for pharmacologic intervention.

Journal: Transplantation 20100727

Title: [Effect of statin therapy on mortality in patients with non-ischemic dilated cardiomyopathy].

Journal: Zhonghua yi xue za zhi 20100727

Title: Anti-obesity and antihyperlipidaemic effect of Hunteria umbellata seed extract in experimental hyperlipidaemia.

Journal: Journal of ethnopharmacology 20100720

Title: Therapeutics. Fenofibrate plus simvastatin did not prevent major CV events more than simvastatin alone in type 2 diabetes.

Journal: Annals of internal medicine 20100720

Title: Effect of simvastatin on Kruppel-like factor2, endothelial nitric oxide synthase and thrombomodulin expression in endothelial cells under shear stress.

Journal: Life sciences 20100717

Title: Simvastatin improves clinical scores in a rabbit multiple infarct ischemic stroke model: synergism with a ROCK inhibitor but not the thrombolytic tissue plasminogen activator.

Journal: Brain research 20100716

Title: The characteristics and mechanism of simvastatin loaded lipid nanoparticles to increase oral bioavailability in rats.

Journal: International journal of pharmaceutics 20100715

Title: Combination treatment of experimental stroke with Niaspan and Simvastatin, reduces axonal damage and improves functional outcome.

Journal: Journal of the neurological sciences 20100715

Title: Statin medication use and the risk of biochemical recurrence after radical prostatectomy: results from the Shared Equal Access Regional Cancer Hospital (SEARCH) Database.

Journal: Cancer 20100715

Title: Reduction in risk of progression of diabetic retinopathy.

Journal: The New England journal of medicine 20100715

Title: Effects of medical therapies on retinopathy progression in type 2 diabetes.

Journal: The New England journal of medicine 20100715

Title: Statins for children with familial hypercholesterolemia.

Journal: The Cochrane database of systematic reviews 20100707

Title: Can low doses of simvastatin enhance fracture healing? An experimental study in rabbits.

Journal: Injury 20100701

Title: Simvastatin reduces mortality and hepatic injury after hemorrhage/resuscitation in rats.

Journal: Shock (Augusta, Ga.) 20100701

Title: Reduced LDL-cholesterol levels in patients with coronary artery disease are paralleled by improved endothelial function: An observational study in patients from 2003 and 2007.

Journal: Atherosclerosis 20100701

Title: Local low-dose lovastatin delivery improves the bone-healing defect caused by Nf1 loss of function in osteoblasts.

Journal: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20100701

Title: Pravastatin attenuates carboplatin-induced nephrotoxicity in rodents via peroxisome proliferator-activated receptor alpha-regulated heme oxygenase-1.

Journal: Molecular pharmacology 20100701

Title: Ezetimibe and recent clinical trials: a look on the bright side.

Journal: Expert opinion on drug safety 20100701

Title: The role of simvastatin in the osteogenesis of injectable tissue-engineered bone based on human adipose-derived stromal cells and platelet-rich plasma.

Journal: Biomaterials 20100701

Title: Lipoprotein subfraction cholesterol distribution is proatherogenic in women with type 1 diabetes and insulin resistance.

Journal: Diabetes 20100701

Title: Combined influence of LDLR and HMGCR sequence variation on lipid-lowering response to simvastatin.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20100701

Title: Aortic stenosis and lipids: does intervention work?

Journal: Current opinion in cardiology 20100701

Title: Asymmetric dimethylarginine--a determinant of the effect of the high dose Simvastatin.

Journal: Clinical biochemistry 20100701

Title: Protein geranylgeranylation controls collagenase expression in osteoarthritic cartilage.

Journal: Osteoarthritis and cartilage 20100701

Title: Lipidomics: a tool for studies of atherosclerosis.

Journal: Current atherosclerosis reports 20100701

Title: Simvastatin induces apoptosis and alters cytoskeleton in endometrial stromal cells.

Journal: The Journal of clinical endocrinology and metabolism 20100701

Title: Incremental cholesterol reduction with ezetimibe/simvastatin, atorvastatin and rosuvastatin in UK General Practice (IN-PRACTICE): randomised controlled trial of achievement of Joint British Societies (JBS-2) cholesterol targets.

Journal: International journal of clinical practice 20100701

Title: Simvastatin treatment in patients with relapsing-remitting multiple sclerosis receiving interferon beta 1a: a double-blind randomized controlled trial.

Journal: Multiple sclerosis (Houndmills, Basingstoke, England) 20100701

Title: Statins, inhibitors of 3-hydroxy-3-methylglutaryl-coenzyme A reductase, function as inhibitors of cellular and molecular components involved in type I interferon production.

Journal: Arthritis and rheumatism 20100701

Title: Ezetimibe alone or in combination with simvastatin increases small dense low-density lipoproteins in healthy men: a randomized trial.

Journal: European heart journal 20100701

Title: Simvastatin combined with nifedipine enhances endothelial cell protection by inhibiting ROS generation and activating Akt phosphorylation.

Journal: Acta pharmacologica Sinica 20100701

Title: Simvastatin in psoriasis: ambiguous effects.

Journal: Acta dermato-venereologica 20100701

Title: Statin prescribing in the elderly in the Netherlands: a pharmacy database time trend study.

Journal: Drugs & aging 20100701

Title: 2009 World Congress on the Insulin Resistance Syndrome: cardiovascular disease concepts.

Journal: Diabetes care 20100701

Title: Simvastatin treatment prevents oxidative damage to DNA in whole blood leukocytes of dyslipidemic type 2 diabetic patients.

Journal: Cell biochemistry and function 20100701

Title: Physiogenomic analysis of statin-treated patients: domain-specific counter effects within the ACACB gene on low-density lipoprotein cholesterol?

Journal: Pharmacogenomics 20100701

Title: State generic substitution laws can lower drug outlays under Medicaid.

Journal: Health affairs (Project Hope) 20100701

Title: How can stretching maneuvers involving the neck cause vertebral artery dissection and transient ischemic attack?

Journal: Journal of occupational and environmental medicine 20100701

Title: Money, money, money.

Journal: Drug and therapeutics bulletin 20100701

Title: Simvastatin-induced changes in circulating oxidized low-density lipoprotein in different types of dyslipidemia.

Journal: Heart and vessels 20100701

Title: Statin post-treatment provides protection against simulated ischemia in bovine pulmonary arterial endothelial cells.

Journal: European journal of pharmacology 20100625

Title: Observed and predicted reduction of ischemic cardiovascular events in the Simvastatin and Ezetimibe in Aortic Stenosis trial.

Journal: The American journal of cardiology 20100615

Title: Design, synthesis, and docking of highly hypolipidemic agents: Schizosaccharomyces pombe as a new model for evaluating alpha-asarone-based HMG-CoA reductase inhibitors.

Journal: Bioorganic & medicinal chemistry 20100615

Title: Simvastatin inhibits osteoclast differentiation induced by bone morphogenetic protein-2 and RANKL through regulating MAPK, AKT and Src signaling.

Journal: Regulatory peptides 20100608

Title: Synergistic effects of telmisartan and simvastatin on endothelial progenitor cells.

Journal: Journal of cellular and molecular medicine 20100601

Title: Applicability of non-cholesterol sterols in predicting response in cholesterol metabolism to simvastatin and fluvastatin treatment among hypercholesterolemic men.

Journal: Nutrition, metabolism, and cardiovascular diseases : NMCD 20100601

Title: Reporting of dietary control frameworks in studies on simvastatin efficacy.

Journal: Clinical nutrition (Edinburgh, Scotland) 20100601

Title: Effect of statins on HDL-C: a complex process unrelated to changes in LDL-C: analysis of the VOYAGER Database.

Journal: Journal of lipid research 20100601

Title: Increased cortisol levels are associated with delayed cerebral ischemia after aneurysmal subarachnoid hemorrhage.

Journal: Neurocritical care 20100601

Title: Cardiovascular outcomes and their relationships to lipoprotein components in patients with and without chronic kidney disease: results from the IDEAL trial.

Journal: Journal of internal medicine 20100601

Title: Liposomal simvastatin attenuates neointimal hyperplasia in rats.

Journal: The AAPS journal 20100601

Title: Role of modulation of vascular endothelial growth factor and tumor necrosis factor-alpha in gastric ulcer healing in diabetic rats.

Journal: Biochemical pharmacology 20100601

Title: Effects of atorvastatin 20 mg, rosuvastatin 10 mg, and atorvastatin/ezetimibe 5 mg/5 mg on lipoproteins and glucose metabolism.

Journal: Journal of cardiovascular pharmacology and therapeutics 20100601

Title: Impact of analyzing less image frames per segment for radiofrequency-based volumetric intravascular ultrasound measurements in mild-to-moderate coronary atherosclerosis.

Journal: The international journal of cardiovascular imaging 20100601

Title: Improved endothelial function with simvastatin but unchanged insulin sensitivity with simvastatin or ezetimibe.

Journal: Metabolism: clinical and experimental 20100601

Title: Impact of lipid raft integrity on 5-HT3 receptor function and its modulation by antidepressants.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20100601

Title: Selection of alternative CYP3A4 probe substrates for clinical drug interaction studies using in vitro data and in vivo simulation.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20100601

Title: Hepatic metabolism and transporter gene variants enhance response to rosuvastatin in patients with acute myocardial infarction: the GEOSTAT-1 Study.

Journal: Circulation. Cardiovascular genetics 20100601

Title: Simvastatin potentiates the anti-hepatitis B virus activity of FDA-approved nucleoside analogue inhibitors in vitro.

Journal: Antiviral research 20100601

Title: Activation of AMP-activated protein kinase inhibits oxidized LDL-triggered endoplasmic reticulum stress in vivo.

Journal: Diabetes 20100601

Title: Usefulness of exercise-stress echocardiography for risk stratification of true asymptomatic patients with aortic valve stenosis.

Journal: European heart journal 20100601

Title: Development and statistical optimization of solid lipid nanoparticles of simvastatin by using 2(3) full-factorial design.

Journal: AAPS PharmSciTech 20100601

Title: Inhibition of reactive oxygen species by Lovastatin downregulates vascular endothelial growth factor expression and ameliorates blood-retinal barrier breakdown in db/db mice: role of NADPH oxidase 4.

Journal: Diabetes 20100601

Title: Effect of statin therapy on leptin levels in patients with coronary heart disease.

Journal: Peptides 20100601

Title: Thermodynamics of RTA3 peptide binding to membranes and consequences for antimicrobial activity.

Journal: Biochimica et biophysica acta 20100601

Title: Simvastatin attenuates acrolein-induced mucin production in rats: involvement of the Ras/extracellular signal-regulated kinase pathway.

Journal: International immunopharmacology 20100601

Title: Simvastatin stimulates production of the antiapoptotic protein Bcl-2 via endothelin-1 and NFATc3 in SH-SY5Y cells.

Journal: Molecular neurobiology 20100601

Title: 3-Hydroxymethyl coenzyme A reductase inhibition attenuates spontaneous smooth muscle tone via RhoA/ROCK pathway regulated by RhoA prenylation.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20100601

Title: Mitochondrial dysfunction induced by statin contributes to endothelial dysfunction in patients with coronary artery disease.

Journal: Cardiovascular toxicology 20100601

Title: Hotline update of clinical trials and registries presented at the American College of Cardiology Congress 2010: ACCORD, INVEST, NAVIGATOR, RACE II, SORT OUT III, CSP-474, DOSE, ASPIRE and more.

Journal: Clinical research in cardiology : official journal of the German Cardiac Society 20100601

Title: Retrospective, observation study: Quantitative and qualitative effect of ezetimibe and HMG-CoA reductase inhibitors on LDL-cholesterol: are there disappearance thresholds for small, dense LDL and IDL?

Journal: Recent patents on cardiovascular drug discovery 20100601

Title: Asymmetric septal hypertrophy - a marker of hypertension in aortic stenosis (a SEAS substudy).

Journal: Blood pressure 20100601

Title: Update on antithrombotic therapy for stroke prevention in atrial fibrillation.

Journal: Current treatment options in cardiovascular medicine 20100601

Title: Critical limb ischemia.

Journal: Current treatment options in cardiovascular medicine 20100601

Title: Influence of simvastatin on apoB-100 secretion in non-obese subjects with mild hypercholesterolemia.

Journal: Lipids 20100601

Title: Effect of linagliptin (BI 1356) on the steady-state pharmacokinetics of simvastatin.

Journal: International journal of clinical pharmacology and therapeutics 20100601

Title: The inhibitory effect of statins on urinary 11-dehydrothromboxane levels.

Journal: International angiology : a journal of the International Union of Angiology 20100601

Title: Aspirin for primary prevention of cardiovascular events in people with diabetes: a position statement of the American Diabetes Association, a scientific statement of the American Heart Association, and an expert consensus document of the American College of Cardiology Foundation.

Journal: Diabetes care 20100601

Title: Integrin beta4 attenuates SHP-2 and MAPK signaling and reduces human lung endothelial inflammatory responses.

Journal: Journal of cellular biochemistry 20100601

Title: Low density lipoprotein-cholesterol variability in patients with type 2 diabetes taking atorvastatin compared to simvastatin: justification for direct measurement?

Journal: Diabetes, obesity & metabolism 20100601

Title: Impact of pressure recovery on echocardiographic assessment of asymptomatic aortic stenosis: a SEAS substudy.

Journal: JACC. Cardiovascular imaging 20100601

Title: Severe statin-induced rhabdomyolysis mimicking Guillain-Barré syndrome in four patients with diabetes mellitus treated with fusidic acid.

Journal: Diabetic medicine : a journal of the British Diabetic Association 20100601

Title: On call. I'm a 61-year-old man with high blood pressure. My doctor wants me to take Zocor to lower my cholesterol, but I'm worried about muscle damage. I found a Web site that claimed coenyzme Q(10) would help. Is that right?

Journal: Harvard men's health watch 20100601

Title: How does short-term low-dose simvastatin influence serum prohepcidin levels in patients with end-stage renal disease? A pilot study.

Journal: Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy 20100601

Title: In vitro synergistic interactions of the effects of various statins and azoles against some clinically important fungi.

Journal: FEMS microbiology letters 20100601

Title: Effect of Chinese herbal medicine for activating blood circulation and detoxifying on expression of inflammatory reaction and tissue damage related factors in experimental carotid artery thrombosis rats.

Journal: Chinese journal of integrative medicine 20100601

Title: Efficacy study of Prunus amygdalus (almond) nuts in scopolamine-induced amnesia in rats.

Journal: Indian journal of pharmacology 20100601

Title: Why do we need multifunctional neuroprotective and neurorestorative drugs for Parkinson's and Alzheimer's diseases as disease modifying agents.

Journal: Experimental neurobiology 20100601

Title: Simvastatin lowers reactive oxygen species level by Nrf2 activation via PI3K/Akt pathway.

Journal: Biochemical and biophysical research communications 20100528

Title: Colloid formation by drugs in simulated intestinal fluid.

Journal: Journal of medicinal chemistry 20100527

Title: Baseline lipoprotein lipids and low-density lipoprotein cholesterol response to prescription omega-3 acid ethyl ester added to Simvastatin therapy.

Journal: The American journal of cardiology 20100515

Title: Effect of obesity on left ventricular mass and systolic function in patients with asymptomatic aortic stenosis (a Simvastatin Ezetimibe in Aortic Stenosis [SEAS] substudy).

Journal: The American journal of cardiology 20100515

Title: Simvastatin as a treatment for pulmonary hypertension trial.

Journal: American journal of respiratory and critical care medicine 20100515

Title: A historical perspective on the discovery of statins.

Journal: Proceedings of the Japan Academy. Series B, Physical and biological sciences 20100511

Title: Lipophilic but not hydrophilic statins selectively induce cell death in gynaecological cancers expressing high levels of HMGCoA reductase.

Journal: Journal of cellular and molecular medicine 20100501

Title: The role of nitric oxide in the expression of renal aquaporin 2 in a cirrhotic rat model: does an AVP-independent mechanism exist for the regulation of AQP2 expression?

Journal: Digestive diseases and sciences 20100501

Title: Prior simvastatin treatment is associated with reduced thrombin generation and platelet activation in patients with acute ST-segment elevation myocardial infarction.

Journal: Thrombosis research 20100501

Title: Double impact on p-glycoprotein by statins enhances doxorubicin cytotoxicity in human neuroblastoma cells.

Journal: International journal of cancer 20100501

Title: Simvastatin protects diabetic rats against kidney injury through the suppression of renal matrix metalloproteinase-9 expression.

Journal: Journal of endocrinological investigation 20100501

Title: Statins inhibit cyclooxygenase-2 and matrix metalloproteinase-9 in human endothelial cells: anti-angiogenic actions possibly contributing to plaque stability.

Journal: Cardiovascular research 20100501

Title: Inhibition of apoptosis in human retinal pigment epithelial cells treated with benzo(e)pyrene, a toxic component of cigarette smoke.

Journal: Investigative ophthalmology & visual science 20100501

Title: Early vascular and metabolic effects of rosuvastatin compared with simvastatin in patients with type 2 diabetes.

Journal: Atherosclerosis 20100501

Title: Simvastatin induces derepression of PTEN expression via NFkappaB to inhibit breast cancer cell growth.

Journal: Cellular signalling 20100501

Title: Long-term treatment with pitavastatin is effective and well tolerated by patients with primary hypercholesterolemia or combined dyslipidemia.

Journal: Atherosclerosis 20100501

Title: Hair growth defects in Insig-deficient mice caused by cholesterol precursor accumulation and reversed by simvastatin.

Journal: The Journal of investigative dermatology 20100501

Title: A homogeneous cell-based assay for measurement of endogenous paraoxonase 1 activity.

Journal: Analytical biochemistry 20100501

Title: Use of the entero-test, a novel approach for the noninvasive capture of biliary metabolites in dogs.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20100501

Title: Relationships between metabolic syndrome and other baseline factors and the efficacy of ezetimibe/simvastatin and atorvastatin in patients with type 2 diabetes and hypercholesterolemia.

Journal: Diabetes care 20100501

Title: Antiangiogenic mechanisms of simvastatin in retinal endothelial cells.

Journal: Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20100501

Title: Effect of ezetimibe on hepatic fat, inflammatory markers, and apolipoprotein B-100 kinetics in insulin-resistant obese subjects on a weight loss diet.

Journal: Diabetes care 20100501

Title: Simvastatin decreases endothelial progenitor cell apoptosis in the kidney of hypertensive hypercholesterolemic pigs.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20100501

Title: The effect of simvastatin on the proteome of detergent-resistant membrane domains: decreases of specific proteins previously related to cytoskeleton regulation, calcium homeostasis and cell fate.

Journal: Proteomics 20100501

Title: IL-6 and high glucose synergistically upregulate MMP-1 expression by U937 mononuclear phagocytes via ERK1/2 and JNK pathways and c-Jun.

Journal: Journal of cellular biochemistry 20100501

Title: Cost-effectiveness of rosuvastatin versus ezetimibe/simvastatin in managing dyslipidemic patients in Mexico.

Journal: Current medical research and opinion 20100501

Title: Different effects of commonly prescribed statins on abdominal aortic aneurysm wall biology.

Journal: European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery 20100501

Title: Increased expression of plasminogen activator inhibitor type-1 (PAI-1) in HEPG2 cells induced by insulin mediated by the 3'-untranslated region of the PAI-1 gene and its pharmacologic implications.

Journal: Coronary artery disease 20100501

Title: Colesevelam lowers glucose and lipid levels in type 2 diabetes: the clinical evidence.

Journal: Diabetes, obesity & metabolism 20100501

Title: Adding insulin glargine vs. NPH insulin to metformin results in a more efficient postprandial beta-cell protection in individuals with type 2 diabetes.

Journal: Diabetes, obesity & metabolism 20100501

Title: Epidemiologic relationships between A1C and all-cause mortality during a median 3.4-year follow-up of glycemic treatment in the ACCORD trial.

Journal: Diabetes care 20100501

Title: An update on the IMProved reduction of outcomes: Vytorin Efficacy International Trial (IMPROVE-IT) design.

Journal: American heart journal 20100501

Title: Efficacy of cholesterol uptake inhibition added to statin therapy among subjects following a low-carbohydrate diet: a randomized controlled trial.

Journal: American heart journal 20100501

Title: Effects of combined therapy with ezetimibe plus simvastatin after drug-eluting stent implantation in a porcine coronary restenosis model.

Journal: Journal of Korean medical science 20100501

Title: Approach to the patient who is intolerant of statin therapy.

Journal: The Journal of clinical endocrinology and metabolism 20100501

Title: The utility of observational studies in clinical decision making: lessons learned from statin trials.

Journal: Postgraduate medicine 20100501

Title: Early outcome of acute ischemic stroke in hyperlipidemic patients under atorvastatin versus simvastatin.

Journal: Clinical neuropharmacology 20100501

Title: Efficacy and safety of extended-release niacin/laropiprant plus statin vs. doubling the dose of statin in patients with primary hypercholesterolaemia or mixed dyslipidaemia.

Journal: International journal of clinical practice 20100501

Title: [The effect of simvastatin on the expression of high mobility group box-1 protein in atherosclerotic rats].

Journal: Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue 20100501

Title: [Experimental study on simvastatin in prevention and treatment of aseptic loosening of prosthesis].

Journal: Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery 20100501

Title: Outcome measurement in economic evaluations of public health interventions: a role for the capability approach?

Journal: International journal of environmental research and public health 20100501

Title: [Effects of simvastatin on proliferation and transition of phenotype in PDGF-BB-induced pulmonary artery smooth muscle cells].

Journal: Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20100501

Title: Concomitant administration of simvastatin and danazol associated with fatal rhabdomyolysis.

Journal: Clinical therapeutics 20100501

Title: Olanzapine induced hyponatraemia.

Journal: The Ulster medical journal 20100501

Title: The Role of Asymmetric Dimethylarginine (ADMA) in Endothelial Dysfunction and Cardiovascular Disease.

Journal: Current cardiology reviews 20100501

Title: Impact of Fenofibrate on Type 2 Diabetes Patients with Features of the Metabolic Syndrome: Subgroup Analysis From FIELD.

Journal: Current cardiology reviews 20100501

Title: Lipid metabolism and HCV infection.

Journal: Viruses 20100501

Title: Multiplex coherent anti-stokes Raman spectroscopy images intact atheromatous lesions and concomitantly identifies distinct chemical profiles of atherosclerotic lipids.

Journal: Circulation research 20100430

Title: Effects of combination lipid therapy in type 2 diabetes mellitus.

Journal: The New England journal of medicine 20100429

Title: ACCORD and Risk-Factor Control in Type 2 Diabetes.

Journal: The New England journal of medicine 20100429

Title: Sustained release of water-insoluble simvastatin from biodegradable hydrogel augments bone regeneration.

Journal: Journal of controlled release : official journal of the Controlled Release Society 20100419

Title: Effect of simvastatin on cholesterol metabolism in C2C12 myotubes and HepG2 cells, and consequences for statin-induced myopathy.

Journal: Biochemical pharmacology 20100415

Title: Preparation, characterization, and anticancer effects of simvastatin-tocotrienol lipid nanoparticles.

Journal: International journal of pharmaceutics 20100415

Title: Differential effects of statins (pravastatin or simvastatin) on ventricular ectopic complexes: Galpha(i2), a possible molecular marker for ventricular irritability.

Journal: The American journal of cardiology 20100415

Title: Another side to statin-related side effects.

Journal: Annals of internal medicine 20100406

Title: Generic substitution of commonly used medications: Australia-wide experience, 2007-2008.

Journal: The Medical journal of Australia 20100405

Title: Saving lives, money and resources: drug and CABG/PCI use after myocardial infarction in a Swedish record-linkage study.

Journal: The European journal of health economics : HEPAC : health economics in prevention and care 20100401

Title: Polyunsaturated fatty acids protect against prion-mediated synapse damage in vitro.

Journal: Neurotoxicity research 20100401

Title: Baseline cholesterol absorption and the response to ezetimibe/simvastatin therapy: a post-hoc analysis of the ENHANCE trial.

Journal: Journal of lipid research 20100401

Title: Sympathoinhibitory effect of statins in chronic heart failure.

Journal: Clinical autonomic research : official journal of the Clinical Autonomic Research Society 20100401

Title: Molecular and tissue responses in the healing of rat calvarial defects after local application of simvastatin combined with alpha tricalcium phosphate.

Journal: Journal of biomedical materials research. Part B, Applied biomaterials 20100401

Title: Validation of an in vitro screening test for predicting the tumor promoting potential of chemicals based on gene expression.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20100401

Title: Statin-triggered cell death in primary human lung mesenchymal cells involves p53-PUMA and release of Smac and Omi but not cytochrome c.

Journal: Biochimica et biophysica acta 20100401

Title: Effects of statins vs. non-statin lipid-lowering therapy on bone formation and bone mineral density biomarkers in patients with hyperlipidemia.