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81093-37-0,MFCD00869375
Catalog No.:AA0039JO

81093-37-0 | (βR,δR,1S,2S,6S,8S,8aR)-1,2,6,7,8,8a-Hexahydro-β,δ,6-trihydroxy-2-methyl-8-[(2S)-2-methyl-1-oxobutoxy]-1-naphthaleneheptanoic acid

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100mg
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$518.00   $363.00
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500mg
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1g
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA0039JO
Chemical Name:
(βR,δR,1S,2S,6S,8S,8aR)-1,2,6,7,8,8a-Hexahydro-β,δ,6-trihydroxy-2-methyl-8-[(2S)-2-methyl-1-oxobutoxy]-1-naphthaleneheptanoic acid
CAS Number:
81093-37-0
Molecular Formula:
C23H36O7
Molecular Weight:
424.5277
MDL Number:
MFCD00869375
SMILES:
CC[C@@H](C(=O)O[C@H]1C[C@H](O)C=C2[C@H]1[C@@H](CC[C@H](C[C@H](CC(=O)O)O)O)[C@H](C=C2)C)C
Properties
Computed Properties
 
Complexity:
656  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
8  
Heavy Atom Count:
30  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
4  
Rotatable Bond Count:
11  
XLogP3:
1.6  

Literature

Title: Differential Regulation of Gene Expression by Cholesterol Biosynthesis Inhibitors That Reduce (Pravastatin) or Enhance (Squalestatin 1) Nonsterol Isoprenoid Levels in Primary Cultured Mouse and Rat Hepatocytes.

Journal: The Journal of pharmacology and experimental therapeutics 20160801

Title: Chronic use of pravastatin reduces insulin exocytosis and increases β-cell death in hypercholesterolemic mice.

Journal: Toxicology 20160217

Title: Pravastatin and Sarpogrelate Synergistically Ameliorate Atherosclerosis in LDLr-Knockout Mice.

Journal: PloS one 20160101

Title: Statins alter the hepatobiliary transport of unconjugated and conjugated bilirubin in sandwich-cultured rat hepatocytes.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20140901

Title: Simvastatin-lnduced nocturnal leg pain disappears with pravastatin substitution.

Journal: Srpski arhiv za celokupno lekarstvo 20130101

Title: Influence of SLCO1B1 polymorphisms on the drug-drug interaction between darunavir/ritonavir and pravastatin.

Journal: Journal of clinical pharmacology 20121101

Title: The role of statin therapy in the prevention of atrial fibrillation: a meta-analysis of randomized controlled trials.

Journal: British journal of clinical pharmacology 20121101

Title: Statin use and the risk of Clostridium difficile in academic medical centres.

Journal: Gut 20121101

Title: Anti-cancer characteristics of mevinolin against three different solid tumor cell lines was not solely p53-dependent.

Journal: Journal of enzyme inhibition and medicinal chemistry 20121001

Title: Statin myopathy: a lipid clinic experience on the tolerability of statin rechallenge.

Journal: Cardiovascular therapeutics 20121001

Title: Atorvastatin and pitavastatin enhance lipoprotein lipase production in L6 skeletal muscle cells through activation of adenosine monophosphate-activated protein kinase.

Journal: Metabolism: clinical and experimental 20121001

Title: Physiologically based modeling of pravastatin transporter-mediated hepatobiliary disposition and drug-drug interactions.

Journal: Pharmaceutical research 20121001

Title: Development and validation of a simple and fast HPLC method for determination of lovastatin, pravastatin and simvastatin.

Journal: Journal of chromatographic science 20121001

Title: Pravastatin normalizes ET-1-induced contraction in the aorta of type 2 diabetic OLETF rats by suppressing the KSR1/ERK complex.

Journal: American journal of physiology. Heart and circulatory physiology 20121001

Title: Pravastatin does not prevent antiphospholipid antibody-mediated changes in human first trimester trophoblast function.

Journal: Human reproduction (Oxford, England) 20121001

Title: Association of cholesteryl ester transfer protein mass with peripheral leukocyte count following statin therapy: a pilot study.

Journal: American journal of cardiovascular drugs : drugs, devices, and other interventions 20121001

Title: Effect of a treatment strategy consisting of pravastatin, vitamin E, and homocysteine lowering on arterial compliance and distensibility in patients with mild-to-moderate chronic kidney disease.

Journal: Clinical nephrology 20121001

Title: Effects of rosuvastatin versus pravastatin on low-density lipoprotein diameter in HIV-1-infected patients receiving ritonavir-boosted protease inhibitor.

Journal: AIDS (London, England) 20120910

Title: Simvastatin evokes an unpredicted inhibition of β-adrenoceptor-mediated vasodilatation in porcine coronary artery.

Journal: European journal of pharmacology 20120905

Title: Organic anion-transporting polypeptides 1a/1b control the hepatic uptake of pravastatin in mice.

Journal: Molecular pharmaceutics 20120904

Title: Pravastatin-induced proangiogenic effects depend upon extracellular FGF-2.

Journal: Journal of cellular and molecular medicine 20120901

Title: Pravastatin reverses the membrane cholesterol reorganization induced by myocardial infarction within lipid rafts in CD14(+)/CD16(-) circulating monocytes.

Journal: Biochimica et biophysica acta 20120901

Title: Accelerated platelet inhibition by switching from atorvastatin to a non-CYP3A4-metabolized statin in patients with high platelet reactivity (ACCEL-STATIN) study.

Journal: European heart journal 20120901

Title: Importance of assessing the effect of statins on the function of high- density lipoproteins on coronary plaque.

Journal: Cardiovascular & hematological disorders drug targets 20120901

Title: Role of genetic factors in statins side-effects.

Journal: Cardiovascular & hematological disorders drug targets 20120901

Title: Use of mechanistic modeling to assess interindividual variability and interspecies differences in active uptake in human and rat hepatocytes.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20120901

Title: Genetic variation in galectin-3 gene associates with cognitive function at old age.

Journal: Neurobiology of aging 20120901

Title: Pravastatin suppresses matrix metalloproteinase expression and activity in human articular chondrocytes stimulated by interleukin-1β.

Journal: Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology 20120901

Title: Impacts of estimated glomerular filtration rate on coronary atherosclerosis and plaque composition before and during statin therapy in patients with normal to mild renal dysfunction: subanalysis of the TRUTH study.

Journal: Nephrology (Carlton, Vic.) 20120901

Title: The safety and effectiveness of statins as treatment for HIV-dyslipidemia: the evidence so far and the future challenges.

Journal: Expert opinion on pharmacotherapy 20120901

Title: Statins and new-onset diabetes: a retrospective longitudinal cohort study.

Journal: Clinical therapeutics 20120901

Title: Can statins reduce the inflammatory response associated with preterm birth in an animal model?

Journal: American journal of obstetrics and gynecology 20120901

Title: Prediction of the in vivo OATP1B1-mediated drug-drug interaction potential of an investigational drug against a range of statins.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20120830

Title: Chronic cyclosporine nephropathy is characterized by excessive autophagosome formation and decreased autophagic clearance.

Journal: Transplantation 20120815

Title: Clinical response to statins: mechanism(s) of variable activity and adverse effects.

Journal: Annals of medicine 20120801

Title: Poor maternal nutrition programmes a pro-atherosclerotic phenotype in ApoE-/- mice.

Journal: Clinical science (London, England : 1979) 20120801

Title: Pravastatin inhibits advanced glycation end products (AGEs)-induced proximal tubular cell apoptosis and injury by reducing receptor for AGEs (RAGE) level.

Journal: Metabolism: clinical and experimental 20120801

Title: Pravastatin and simvastatin improves acetylsalicylic acid-mediated in vitro blood platelet inhibition.

Journal: European journal of clinical investigation 20120801

Title: Elevated concentration of placental growth factor (PlGF) and long term risk in patients with acute coronary syndrome in the PROVE IT-TIMI 22 trial.

Journal: Journal of thrombosis and thrombolysis 20120801

Title: Dyslipidemia and its therapeutic challenges in renal transplantation.

Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20120801

Title: Coenzyme Q10 reverses mitochondrial dysfunction in atorvastatin-treated mice and increases exercise endurance.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20120801

Title: Involvement of cholesterol efflux pathway in the control of cardiomyocytes cholesterol homeostasis.

Journal: Journal of molecular and cellular cardiology 20120801

Title: Association of the low-density lipoprotein cholesterol/high-density lipoprotein cholesterol ratio and body mass index with coronary plaque regression.

Journal: American journal of cardiovascular drugs : drugs, devices, and other interventions 20120801

Title: Erythrocyte-mediated delivery of pravastatin: in vitro study of effect of hypotonic lysis on biochemical parameters and loading efficiency.

Journal: Archives of pharmacal research 20120801

Title: Prospective, randomized, single-blind comparison of effects of 6 months' treatment with atorvastatin versus pravastatin on leptin and angiogenic factors in patients with coronary artery disease.

Journal: Heart and vessels 20120701

Title: Modulation of h(2)s metabolism by statins: a new aspect of cardiovascular pharmacology.

Journal: Antioxidants & redox signaling 20120701

Title: Comparative efficacy and safety of fenofibrate/pravastatin plus ezetimibe triple therapy and simvastatin/ezetimibe dual therapy in type 2 diabetic patients with mixed hyperlipidaemia and cardiovascular disease.

Journal: Diabetes & vascular disease research 20120701

Title: Randomized comparison of pitavastatin and pravastatin treatment on the reduction of urinary albumin in patients with type 2 diabetic nephropathy.

Journal: Diabetes, obesity & metabolism 20120701

Title: Effects of bile salts on gastrointestinal absorption of pravastatin.

Journal: Journal of pharmaceutical sciences 20120701

Title: Mediating effects of aryl-hydrocarbon receptor and RhoA in altering brain vascular integrity: the therapeutic potential of statins.

Journal: The American journal of pathology 20120701

Title: Cholesterol level goal attainment with statins: clinical management guideline recommendations versus management in actual clinical practice.

Journal: Pharmacotherapy 20120701

Title: ACP Journal Club. Review: Perioperative statins reduce perioperative MI and AF in statin-naïve patients.

Journal: Annals of internal medicine 20120619

Title: Role of non-high-density lipoprotein cholesterol in predicting cerebrovascular events in patients following myocardial infarction.

Journal: The American journal of cardiology 20120615

Title: Cost-effectiveness of extended-release niacin/laropiprant added to a stable simvastatin dose in secondary prevention patients not at cholesterol goal in Germany.

Journal: The European journal of health economics : HEPAC : health economics in prevention and care 20120601

Title: Blood pressure control status and effects of pravastatin on cardiovascular events occurrence in patients with dyslipidaemia.

Journal: Journal of human hypertension 20120601

Title: Potential role of statins on wound healing: review of the literature.

Journal: International wound journal 20120601

Title: Patient socioeconomic determinants for the choice of the cheapest molecule within a cluster: evidence from Belgian prescription data.

Journal: The European journal of health economics : HEPAC : health economics in prevention and care 20120601

Title: Pravastatin normalizes endothelium-derived contracting factor-mediated response via suppression of Rho-kinase signalling in mesenteric artery from aged type 2 diabetic rat.

Journal: Acta physiologica (Oxford, England) 20120601

Title: Molecular pathways regulating macrophage polarization: implications for atherosclerosis.

Journal: Current atherosclerosis reports 20120601

Title: Short-term statin administration in hypercholesterolaemic rabbits resistant to postconditioning: effects on infarct size, endothelial nitric oxide synthase, and nitro-oxidative stress.

Journal: Cardiovascular research 20120601

Title: A Na+-phosphate cotransporter homologue (SLC17A4 protein) is an intestinal organic anion exporter.

Journal: American journal of physiology. Cell physiology 20120601

Title: The effect of low-dose pravastatin in metabolic syndrome for primary prevention of cardiovascular disease in Japan: a post hoc analysis of the MEGA study.

Journal: Journal of cardiovascular pharmacology and therapeutics 20120601

Title: [Effects of Chinese herbal medicine Shoushen Granule on telomere length and telomerase activity of peripheral white blood cells and vascular cells in rats with atherosclerosis].

Journal: Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20120601

Title: Effects of pravastatin or 12/15 lipoxygenase pathway inhibitors on indices of diabetic nephropathy in an experimental model of diabetic renal disease.

Journal: Saudi medical journal 20120601

Title: Effect of Huxin Formula on reverse cholesterol transport in ApoE-gene knockout mice.

Journal: Chinese journal of integrative medicine 20120601

Title: The evaluation of analgesic effects of simvastatin, pravastatin and atorvastatin in hot plate test.

Journal: European review for medical and pharmacological sciences 20120601

Title: Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.

Journal: Journal of medicinal chemistry 20120524

Title: The differential effects of statins on the metastatic behaviour of prostate cancer.

Journal: British journal of cancer 20120508

Title: Pravastatin inhibits farnesol production in Candida albicans and improves survival in a mouse model of systemic candidiasis.

Journal: Medical mycology 20120501

Title: Inhibition of the organic anion-transporting polypeptide 1B1 by quercetin: an in vitro and in vivo assessment.

Journal: British journal of clinical pharmacology 20120501

Title: EPR studies on hydroxyl radical-scavenging activities of pravastatin and fluvastatin.

Journal: Molecular and cellular biochemistry 20120501

Title: Using expression data for quantification of active processes in physiologically based pharmacokinetic modeling.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20120501

Title: Rapamycin toxicity in MIN6 cells and rat and human islets is mediated by the inhibition of mTOR complex 2 (mTORC2).

Journal: Diabetologia 20120501

Title: Early treatment with olmesartan prevents juxtamedullary glomerular podocyte injury and the onset of microalbuminuria in type 2 diabetic rats.

Journal: American journal of hypertension 20120501

Title: Mechanistic pharmacokinetic modeling for the prediction of transporter-mediated disposition in humans from sandwich culture human hepatocyte data.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20120501

Title: Genome-wide association study of genetic determinants of LDL-c response to atorvastatin therapy: importance of Lp(a).

Journal: Journal of lipid research 20120501

Title: Inhibitory effect of statins on inflammatory cytokine production from human bronchial epithelial cells.

Journal: Clinical and experimental immunology 20120501

Title: Assaying embryotoxicity in the test tube: current limitations of the embryonic stem cell test (EST) challenging its applicability domain.

Journal: Critical reviews in toxicology 20120501

Title: Pharmacogenetics of statins: achievements, whole-genome analyses and future perspectives.

Journal: Pharmacogenomics 20120501

Title: Pravastatin and fenofibrate in combination (Pravafenix(®)) for the treatment of high-risk patients with mixed hyperlipidemia.

Journal: Expert review of cardiovascular therapy 20120501

Title: Pravastatin attenuates noise-induced cochlear injury in mice.

Journal: Neuroscience 20120419

Title: RNAi-mediated knockdown of HMG CoA reductase enhances gene expression from physiologically regulated low-density lipoprotein receptor therapeutic vectors in vivo.

Journal: Gene therapy 20120401

Title: Simultaneous assessment of uptake and metabolism in rat hepatocytes: a comprehensive mechanistic model.

Journal: The Journal of pharmacology and experimental therapeutics 20120401

Title: The ghrelin gene products and exendin-4 promote survival of human pancreatic islet endothelial cells in hyperglycaemic conditions, through phosphoinositide 3-kinase/Akt, extracellular signal-related kinase (ERK)1/2 and cAMP/protein kinase A (PKA) signalling pathways.

Journal: Diabetologia 20120401

Title: Complete mitochondrial genome of compactin-producing fungus Penicillium solitum and comparative analysis of Trichocomaceae mitochondrial genomes.

Journal: FEMS microbiology letters 20120401

Title: Direct to consumer Internet advertising of statins: an assessment of safety.

Journal: Pharmacoepidemiology and drug safety 20120401

Title: Diabetes-specific nutrition algorithm: a transcultural program to optimize diabetes and prediabetes care.

Journal: Current diabetes reports 20120401

Title: Mechanisms involved in cardioprotective effects of pravastatin administered during reoxygenation in human myocardium in vitro.

Journal: Anesthesiology 20120401

Title: Safety of a fixed-dose combination of fenofibrate/pravastatin 160 mg/40 mg in patients with mixed hyperlipidaemia: a pooled analysis from a database of clinical trials.

Journal: Clinical drug investigation 20120401

Title: Targeting HDL-cholesterol to reduce residual cardiovascular risk.

Journal: Current opinion in lipidology 20120401

Title: Is statin-associated cognitive impairment clinically relevant? A narrative review and clinical recommendations.

Journal: The Annals of pharmacotherapy 20120401

Title: The Effects of Combined Treatment with an HMG-CoA Reductase Inhibitor and PPARγ Agonist on the Activation of Rat Pancreatic Stellate Cells.

Journal: Gut and liver 20120401

Title: Effects of green tea or Sasa quelpaertensis bamboo leaves on plasma and liver lipids, erythrocyte Na efflux, and platelet aggregation in ovariectomized rats.

Journal: Nutrition research and practice 20120401

Title: Preventing a Cardiovascular Disease Epidemic among Indigenous Populations through Lifestyle Changes.

Journal: International journal of preventive medicine 20120401

Title: Inheritance of coronary artery disease in men: an analysis of the role of the Y chromosome.

Journal: Lancet (London, England) 20120310

Title: Pitavastatin: a review of its use in the management of hypercholesterolaemia or mixed dyslipidaemia.

Journal: Drugs 20120305

Title: Development of a model for prediction of coronary atherosclerotic regression: evaluation of high-density lipoprotein cholesterol level and peripheral blood monocyte count.

Journal: Heart and vessels 20120301

Title: In vitro evaluation of phototoxic properties of proton pump inhibitors, H2-receptor antagonists and statins.

Journal: Acta dermato-venereologica 20120301

Title: Effect of lipophilicity on the bioavailability of drugs after percutaneous administration by dissolving microneedles.

Journal: Journal of pharmaceutical sciences 20120301

Title: In vivo biliary clearance should be predicted by intrinsic biliary clearance in sandwich-cultured hepatocytes.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20120301

Title: Subclinical thyroid dysfunction and the risk of heart failure in older persons at high cardiovascular risk.

Journal: The Journal of clinical endocrinology and metabolism 20120301

Title: Secondary stroke prevention: patent foramen ovale, aortic plaque, and carotid stenosis.

Journal: European heart journal 20120301

Title: Effect of dalcetrapib plus pravastatin on lipoprotein metabolism and high-density lipoprotein composition and function in dyslipidemic patients: results of a phase IIb dose-ranging study.

Journal: American heart journal 20120301

Title: Amino acid and vitamin supplementation improved health conditions in elderly participants.

Journal: Journal of clinical biochemistry and nutrition 20120301

Title: Genome-wide association and functional follow-up reveals new loci for kidney function.

Journal: PLoS genetics 20120301

Title: Effects of 4-week administration of simvastatin in different doses on heart rate and blood pressure after metoprolol injection in normocholesterolaemic and normotensive rats.

Journal: Archives of medical science : AMS 20120227

Title: The impact of statin therapy on long-term cardiovascular outcomes in an outpatient cardiology practice.

Journal: Archives of medical science : AMS 20120227

Title: Reduction in atherosclerotic events: a retrospective study in an outpatient cardiology practice.

Journal: Archives of medical science : AMS 20120227

Title: Determination of pravastatin and pravastatin lactone in rat plasma and urine using UHPLC-MS/MS and microextraction by packed sorbent.

Journal: Talanta 20120215

Title: Atheroprotective communication between endothelial cells and smooth muscle cells through miRNAs.

Journal: Nature cell biology 20120212

Title: Discovery of (S)-6-(3-cyclopentyl-2-(4-(trifluoromethyl)-1H-imidazol-1-yl)propanamido)nicotinic acid as a hepatoselective glucokinase activator clinical candidate for treating type 2 diabetes mellitus.

Journal: Journal of medicinal chemistry 20120209

Title: Pravastatin for thioacetamide-induced hepatic failure and encephalopathy.

Journal: European journal of clinical investigation 20120201

Title: Evaluation of C-reactive protein prior to and on-treatment as a predictor of benefit from atorvastatin: observations from the Anglo-Scandinavian Cardiac Outcomes Trial.

Journal: European heart journal 20120201

Title: The effects of a single nucleotide polymorphism in SLCO1B1 on the pharmacodynamics of pravastatin.

Journal: British journal of clinical pharmacology 20120201

Title: In vitro and in silico strategies to identify OATP1B1 inhibitors and predict clinical drug-drug interactions.

Journal: Pharmaceutical research 20120201

Title: Adverse events associated with individual statin treatments for cardiovascular disease: an indirect comparison meta-analysis.

Journal: QJM : monthly journal of the Association of Physicians 20120201

Title: Pravastatin inhibits C-reactive protein generation induced by fibrinogen, fibrin and FDP in isolated rat vascular smooth muscle cells.

Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20120201

Title: Hypermethylation at loci sensitive to the prenatal environment is associated with increased incidence of myocardial infarction.

Journal: International journal of epidemiology 20120201

Title: A review of the rationale for additional therapeutic interventions to attain lower LDL-C when statin therapy is not enough.

Journal: Current atherosclerosis reports 20120201

Title: Explication of interactions between HMGCR isoform 2 and various statins through In silico modeling and docking.

Journal: Computers in biology and medicine 20120201

Title: Genetic variation at the SLCO1B1 gene locus and low density lipoprotein cholesterol lowering response to pravastatin in the elderly.

Journal: Atherosclerosis 20120201

Title: KIF6, LPA, TAS2R50, and VAMP8 genetic variation, low density lipoprotein cholesterol lowering response to pravastatin, and heart disease risk reduction in the elderly.

Journal: Atherosclerosis 20120201

Title: Identification and characterization of Penicillium citrinum VeA and LaeA as global regulators for ML-236B production.

Journal: Current genetics 20120201

Title: HMG-CoA reductase inhibitors (statins) reduce hypertrophic scar formation in a rabbit ear wounding model.

Journal: Plastic and reconstructive surgery 20120201

Title: Statin treatment for coronary artery plaque composition based on intravascular ultrasound radiofrequency data analysis.

Journal: American heart journal 20120201

Title: Pravastatin reduces steroid-induced osteonecrosis of the femoral head in SHRSP rats.

Journal: Acta orthopaedica 20120201

Title: Plant sterols and cardiovascular disease: a systematic review and meta-analysis.

Journal: European heart journal 20120201

Title: Statin therapy in the elderly: might there be uncertainty in the majority?

Journal: European journal of preventive cardiology 20120201

Title: Statin treatment depresses the fetal defence to acute hypoxia via increasing nitric oxide bioavailability.

Journal: The Journal of physiology 20120115

Title: [Specific considerations on the prescription and therapeutic interchange of statins].

Journal: Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria 20120101

Title: Hypertriglyceridemia, Metabolic Syndrome, and Cardiovascular Disease in HIV-Infected Patients: Effects of Antiretroviral Therapy and Adipose Tissue Distribution.

Journal: International journal of vascular medicine 20120101

Title: Understanding postprandial inflammation and its relationship to lifestyle behaviour and metabolic diseases.

Journal: International journal of vascular medicine 20120101

Title: The chylomicron: relationship to atherosclerosis.

Journal: International journal of vascular medicine 20120101

Title: Effect of intensive lipid-lowering therapy with rosuvastatin on progression of carotid intima-media thickness in Japanese patients: Justification for Atherosclerosis Regression Treatment (JART) study.

Journal: Circulation journal : official journal of the Japanese Circulation Society 20120101

Title: Galectin-3 and the development of heart failure after acute coronary syndrome: pilot experience from PROVE IT-TIMI 22.

Journal: Clinical chemistry 20120101

Title: Usefulness of LDL-C-related parameters to predict cardiovascular risk and effect of pravastatin in mild-to-moderate hypercholesterolemia.

Journal: Journal of atherosclerosis and thrombosis 20120101

Title: The long-term effect of statins on the risk of new-onset diabetes mellitus in elderly Taiwanese patients with hypertension and dyslipidaemia: a retrospective longitudinal cohort study.

Journal: Drugs & aging 20120101

Title: Bilayered transmucosal drug delivery system of pravastatin sodium: statistical optimization, in vitro, ex vivo, in vivo and stability assessment.

Journal: Drug delivery 20120101

Title: Control strategy on hypertension in chinese medicine.

Journal: Evidence-based complementary and alternative medicine : eCAM 20120101

Title: The pathophysiology of HIV-/HAART-related metabolic syndrome leading to cardiovascular disorders: the emerging role of adipokines.

Journal: Experimental diabetes research 20120101

Title: Adverse event profiles of 5-fluorouracil and capecitabine: data mining of the public version of the FDA Adverse Event Reporting System, AERS, and reproducibility of clinical observations.

Journal: International journal of medical sciences 20120101

Title: Atorvastatin treatment is effective when used in combination with mefloquine in an experimental cerebral malaria murine model.

Journal: Malaria journal 20120101

Title: Quantile-specific penetrance of genes affecting lipoproteins, adiposity and height.

Journal: PloS one 20120101

Title: Cholesterol-lowering drugs and incident open-angle glaucoma: a population-based cohort study.

Journal: PloS one 20120101

Title: Effects of bile-acid-binding resin (colestimide) on blood glucose and visceral fat in Japanese patients with type 2 diabetes mellitus and hypercholesterolemia: an open-label, randomized, case-control, crossover study.

Journal: Journal of diabetes and its complications 20120101

Title: Genetic interactions between chromosomes 11 and 18 contribute to airway hyperresponsiveness in mice.

Journal: PloS one 20120101

Title: Lipid disorders in elderly hypertensive patients.

Journal: International journal of hypertension 20120101

Title: The differential effect of statins on oxidative stress and endothelial function: atorvastatin versus pravastatin.

Journal: Journal of clinical lipidology 20120101

Title: Evidence-based prediction of statin use with lipid-panel data from the National Health and Nutrition Examination Survey.

Journal: Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research 20120101

Title: Anticancer efficacy of perillyl alcohol-bearing PLGA microparticles.

Journal: International journal of nanomedicine 20120101

Title: Lack of effect of lowering LDL cholesterol on cancer: meta-analysis of individual data from 175,000 people in 27 randomised trials of statin therapy.

Journal: PloS one 20120101

Title: Proteomic analysis of aortae from human lipoprotein(a) transgenic mice shows an early metabolic response independent of atherosclerosis.

Journal: PloS one 20120101

Title: Preventive pharmacotherapy in type 2 diabetes mellitus.

Journal: Indian journal of endocrinology and metabolism 20120101

Title: Managing atrial fibrillation in the elderly: critical appraisal of dronedarone.

Journal: Clinical interventions in aging 20120101

Title: Effects of sterol regulatory element-binding protein (SREBP) in chickens.

Journal: Lipids in health and disease 20120101

Title: Niacin extended-release/simvastatin combination therapy produces larger favorable changes in high-density lipoprotein particles than atorvastatin monotherapy.

Journal: Vascular health and risk management 20120101

Title: Antihyperlipidemic activity of Salacia chinensis root extracts in triton-induced and atherogenic diet-induced hyperlipidemic rats.

Journal: Indian journal of pharmacology 20120101

Title: Treatment Options in Cushing's Disease.

Journal: Clinical Medicine Insights. Oncology 20120101

Title: Cost-effectiveness of rosuvastatin in comparison with generic atorvastatin and simvastatin in a Swedish population at high risk of cardiovascular events.

Journal: ClinicoEconomics and outcomes research : CEOR 20120101

Title: Pravastatin inhibits cell proliferation and increased MAT1A expression in hepatocarcinoma cells and in vivo models.

Journal: Cancer cell international 20120101

Title: An anti-PCSK9 antibody reduces LDL-cholesterol on top of a statin and suppresses hepatocyte SREBP-regulated genes.

Journal: International journal of biological sciences 20120101

Title: The effect of statin therapy in stroke outcome: a double blind clinical trial.

Journal: International journal of preventive medicine 20120101

Title: Self-microemulsifying drug-delivery system for improved oral bioavailability of probucol: preparation and evaluation.

Journal: International journal of nanomedicine 20120101

Title: A Medicinal Herb Scutellaria lateriflora Inhibits PrP Replication in vitro and Delays the Onset of Prion Disease in Mice.

Journal: Frontiers in psychiatry 20120101

Title: Central versus peripheral cardiovascular risk in metabolic syndrome.

Journal: Frontiers in physiology 20120101

Title: The relation between serum lipids and lutein and zeaxanthin in the serum and retina: results from cross-sectional, case-control and case study designs.

Journal: Lipids in health and disease 20120101

Title: Cholesteryl Ester Transfer Protein (CETP) polymorphisms affect mRNA splicing, HDL levels, and sex-dependent cardiovascular risk.

Journal: PloS one 20120101

Title: NMR evaluation of total statin content and HMG-CoA reductase inhibition in red yeast rice (Monascus spp.) food supplements.

Journal: Chinese medicine 20120101

Title: Rosuvastatin: a review of the pharmacology and clinical effectiveness in cardiovascular disease.

Journal: Clinical Medicine Insights. Cardiology 20120101

Title: Improved preservation of residual beta cell function by atorvastatin in patients with recent onset type 1 diabetes and high CRP levels (DIATOR trial).

Journal: PloS one 20120101

Title: Smoking and idiopathic pulmonary fibrosis.

Journal: Pulmonary medicine 20120101

Title: Nebivolol: impact on cardiac and endothelial function and clinical utility.

Journal: Vascular health and risk management 20120101

Title: LIPITENSION: Interplay between dyslipidemia and hypertension.

Journal: Indian journal of endocrinology and metabolism 20120101

Title: Achieving secondary prevention low-density lipoprotein particle concentration goals using lipoprotein cholesterol-based data.

Journal: PloS one 20120101

Title: Genomics of Dementia: APOE- and CYP2D6-Related Pharmacogenetics.

Journal: International journal of Alzheimer's disease 20120101

Title: Pro-inflammatory S100A8 and S100A9 proteins: self-assembly into multifunctional native and amyloid complexes.

Journal: International journal of molecular sciences 20120101

Title: Effect of a dipeptidyl peptidase-IV inhibitor, des-fluoro-sitagliptin, on neointimal formation after balloon injury in rats.

Journal: PloS one 20120101

Title: Sinusoidal endothelial dysfunction precedes inflammation and fibrosis in a model of NAFLD.

Journal: PloS one 20120101

Title: Efficacy of short-term high-dose statin in preventing contrast-induced nephropathy: a meta-analysis of seven randomized controlled trials.

Journal: PloS one 20120101

Title: A comparative effect of atorvastatin with other statins in patients of hyperlipidemia.

Journal: Indian journal of pharmacology 20120101

Title: Emerging drug combinations to optimize renovascular protection and blood pressure goals.

Journal: International journal of nephrology and renovascular disease 20120101

Title: Recurrent acute pancreatitis probably induced by rosuvastatin therapy: a case report.

Journal: Case reports in medicine 20120101

Title: The effect of rosuvastatin in a murine model of influenza A infection.

Journal: PloS one 20120101

Title: Nitric oxide manipulation: a therapeutic target for peripheral arterial disease?

Journal: Cardiology research and practice 20120101

Title: Anti-inflammatory effect of simvastatin in an experimental model of spinal cord trauma: involvement of PPAR-α.

Journal: Journal of neuroinflammation 20120101

Title: Statins accelerate the onset of collagen type II-induced arthritis in mice.

Journal: Arthritis research & therapy 20120101

Title: Mixed dyslipidemias in primary care patients in France.

Journal: Vascular health and risk management 20120101

Title: A systematic review of xuezhikang, an extract from red yeast rice, for coronary heart disease complicated by dyslipidemia.

Journal: Evidence-based complementary and alternative medicine : eCAM 20120101

Title: The effect of storage temperature and time on the concentrations of bovine serum amyloid a and its mammary associated isoform.

Journal: Veterinary medicine international 20120101

Title: Public health concerns for anti-obesity medicines imported for personal use through the internet: a cross-sectional study.

Journal: BMJ open 20120101

Title: Statin therapy decreases serum levels of high-sensitivity C-reactive protein and tumor necrosis factor-α in HIV-infected patients treated with ritonavir-boosted protease inhibitors.

Journal: HIV clinical trials 20120101

Title: Discontinuation of statin therapy in older people: does a cancer diagnosis make a difference? An observational cohort study using data linkage.

Journal: BMJ open 20120101

Title: Do statins improve outcomes in patients with asthma on inhaled corticosteroid therapy? A retrospective cohort analysis.

Journal: BMJ open 20120101

Title: Controlled release and angiotensin-converting enzyme inhibition properties of an antihypertensive drug based on a perindopril erbumine-layered double hydroxide nanocomposite.

Journal: International journal of nanomedicine 20120101

Title: Efficacy, safety and tolerability of ongoing statin plus ezetimibe versus doubling the ongoing statin dose in hypercholesterolemic Taiwanese patients: an open-label, randomized clinical trial.

Journal: BMC research notes 20120101

Title: Ezetimibe improves endothelial function and inhibits Rho-kinase activity associated with inhibition of cholesterol absorption in humans.

Journal: Circulation journal : official journal of the Japanese Circulation Society 20120101

Title: Diverse spectrum of presentation of coronary slow flow phenomenon: a concise review of the literature.

Journal: Cardiology research and practice 20120101

Title: Sense and nonsense in metabolic control of reproduction.

Journal: Frontiers in endocrinology 20120101

Title: Sterol lipid metabolism in down syndrome revisited: down syndrome is associated with a selective reduction in serum brassicasterol levels.

Journal: Current gerontology and geriatrics research 20120101

Title: Lipid disorders in uremia and dialysis.

Journal: Contributions to nephrology 20120101

Title: The effectiveness and cost effectiveness of dark chocolate consumption as prevention therapy in people at high risk of cardiovascular disease: best case scenario analysis using a Markov model.

Journal: BMJ (Clinical research ed.) 20120101

Title: LDL-apheresis: technical and clinical aspects.

Journal: TheScientificWorldJournal 20120101

Title: Double-dose pravastatin versus add-on ezetimibe with low-dose pravastatin - effects on LDL cholesterol, cholesterol absorption, and cholesterol synthesis in Japanese patients with hypercholesterolemia (PEAS study).

Journal: Journal of atherosclerosis and thrombosis 20120101

Title: Cholesteryl ester transfer-protein modulator and inhibitors and their potential for the treatment of cardiovascular diseases.

Journal: Vascular health and risk management 20120101

Title: Inhibition of intestinal bile acid transporter Slc10a2 improves triglyceride metabolism and normalizes elevated plasma glucose levels in mice.

Journal: PloS one 20120101

Title: Genome-wide study of gene variants associated with differential cardiovascular event reduction by pravastatin therapy.

Journal: PloS one 20120101

Title: Practical application of cytochrome P450.

Journal: Biological & pharmaceutical bulletin 20120101

Title: [Effects of acidification and alkalinization agents on statins-induced muscle toxicity].

Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20120101

Title: Genetics Techniques for Thermococcus kodakarensis.

Journal: Frontiers in microbiology 20120101

Title: Metabolic disorders and steatosis in patients with chronic hepatitis C: metabolic strategies for antiviral treatments.

Journal: International journal of hepatology 20120101

Title: Biomarkers of chronic inflammatory state in uremia and cardiovascular disease.

Journal: International journal of inflammation 20120101

Title: Selected statins produce rapid spinal motor neuron loss in vitro.

Journal: BMC musculoskeletal disorders 20120101

Title: Economic evaluation of statins in high-risk patients treated for primary and secondary prevention of cardiovascular disease in Greece.

Journal: ClinicoEconomics and outcomes research : CEOR 20120101

Title: Atorvastatin and simvastatin, but not pravastatin, up-regulate LPS-induced MMP-9 expression in macrophages by regulating phosphorylation of ERK and CREB.

Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20120101

Title: Statins affect the presentation of endothelial chemokines by targeting to multivesicular bodies.

Journal: PloS one 20120101

Title: [Equivalence studies of pravastatin original and generic drugs by dissolution test].

Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20120101

Title: Effect of pravastatin on endothelial function and endothelial progenitor cells in healthy postmenopausal women.

Journal: Clinical and experimental obstetrics & gynecology 20120101

Title: Pravastatin-induced improvement in coronary reactivity and circulating ATP and ADP levels in young adults with type 1 diabetes.

Journal: Frontiers in physiology 20120101

Title: Rac-induced left ventricular dilation in thyroxin-treated ZmRacD transgenic mice: role of cardiomyocyte apoptosis and myocardial fibrosis.

Journal: PloS one 20120101

Title: A survey of the FDA's AERS database regarding muscle and tendon adverse events linked to the statin drug class.

Journal: PloS one 20120101

Title: Adherence to preferable behavior for lipid control by high-risk dyslipidemic Japanese patients under pravastatin treatment: the APPROACH-J study.

Journal: Journal of atherosclerosis and thrombosis 20120101

Title: Ovariectomized mouse uterotrophic assay of 36 chemicals.

Journal: The Journal of toxicological sciences 20120101

Title: Angiotensin converting enzyme inhibitor and HMG-CoA reductase inhibitor as adjunct treatment for persons with HIV infection: a feasibility randomized trial.

Journal: PloS one 20120101

Title: Effects of pravastatin on the pharmacokinetic parameters of nimodipine after oral and intravenous administration in rats: possible role of CYP3A4 inhibition by pravastatin.

Journal: Indian journal of pharmacology 20120101

Title: Editorial on management of diabetes mellitus with coronary artery disease.

Journal: Archives of medical science : AMS 20111231

Title: Hypotensive effect of atorvastatin in hypertensive patients: the association among flow-mediated dilation, oxidative stress and endothelial dysfunction.

Journal: Archives of medical science : AMS 20111231

Title: IMproving the imPlemEntation of cuRrent guidelines for the mAnagement of major coronary hearT disease rIsk factors by multifactorial interVEntion. The IMPERATIVE renal analysis.

Journal: Archives of medical science : AMS 20111231

Title: Lipids, blood pressure, kidney - what was new in 2011?

Journal: Archives of medical science : AMS 20111231

Title: Chemical inhibitors suggest endophytic fungal paclitaxel is derived from both mevalonate and non-mevalonate-like pathways.

Journal: Journal of natural products 20111227

Title: Effects on 11-year mortality and morbidity of lowering LDL cholesterol with simvastatin for about 5 years in 20,536 high-risk individuals: a randomised controlled trial.

Journal: Lancet (London, England) 20111210

Title: Incorporation of economic evidence in the Dutch guideline 'cardiovascular risk management'.

Journal: Journal of evaluation in clinical practice 20111201

Title: High-density lipoprotein cholesterol as a predictor of clinical outcomes in patients achieving low-density lipoprotein cholesterol targets with statins after percutaneous coronary intervention.

Journal: Heart (British Cardiac Society) 20111201

Title: Opposite effects of pravastatin and atorvastatin on insulin sensitivity in the rat: role of vitamin D metabolites.

Journal: Atherosclerosis 20111201

Title: Familial hypercholesterolemia: present and future management.

Journal: Current cardiology reports 20111201

Title: Is inflammation the cause of pre-eclampsia?

Journal: Biochemical Society transactions 20111201

Title: Fatal rhabdomyolysis in a patient with liver cirrhosis after switching from simvastatin to fluvastatin.

Journal: Journal of Korean medical science 20111201

Title: HMG-CoA reductase inhibitor (Statin) therapy and coronary atherosclerosis in Japanese subjects: role of high-density lipoprotein cholesterol.

Journal: American journal of cardiovascular drugs : drugs, devices, and other interventions 20111201

Title: The inverse relationship between alanine aminotransferase in the normal range and adverse cardiovascular and non-cardiovascular outcomes.

Journal: International journal of epidemiology 20111201

Title: Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).

Journal: PLoS computational biology 20111201

Title: Phospholipase PLA2G7, associated with aggressive prostate cancer, promotes prostate cancer cell migration and invasion and is inhibited by statins.

Journal: Oncotarget 20111201

Title: [Achievement of therapeutic target in subjects on statin treatment in clinical practice. Results of the STAR (Statins Target Assessment in Real practice) study].

Journal: Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace 20111201

Title: What are the Evidence Based Public Health Interventions for Prevention and Control of NCDs in Relation to India?

Journal: Indian journal of community medicine : official publication of Indian Association of Preventive & Social Medicine 20111201

Title: Therapeutic interventions targeting Beta amyloid pathogenesis in an aging dog model.

Journal: Current neuropharmacology 20111201

Title: Cost-effectiveness of the use of low- and high-potency statins in people at low cardiovascular risk.

Journal: CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20111108

Title: Modification of hepatic iron metabolism induced by pravastatin during obstructive cholestasis in rats.

Journal: Life sciences 20111107

Title: Low-dosage statins reduce choroidal damage in hypercholesterolemic rabbits.

Journal: Acta ophthalmologica 20111101

Title: Acute simvastatin increases endothelial nitric oxide synthase phosphorylation via AMP-activated protein kinase and reduces contractility of isolated rat mesenteric resistance arteries.

Journal: Clinical science (London, England : 1979) 20111101

Title: Effect of pravastatin on the frequency of ventilator-associated pneumonia and on intensive care unit mortality: open-label, randomized study.

Journal: Critical care medicine 20111101

Title: The neuroprotective effect of two statins: simvastatin and pravastatin on a streptozotocin-induced model of Alzheimer's disease in rats.

Journal: Journal of neural transmission (Vienna, Austria : 1996) 20111101

Title: Leoligin, the major lignan from Edelweiss, activates cholesteryl ester transfer protein.

Journal: Atherosclerosis 20111101

Title: Differential effect of statins on diabetic nephropathy in db/db mice.

Journal: International journal of molecular medicine 20111101

Title: Drug interactions with mitotane by induction of CYP3A4 metabolism in the clinical management of adrenocortical carcinoma.

Journal: Clinical endocrinology 20111101

Title: Acetoacetyl-CoA thiolase regulates the mevalonate pathway during abiotic stress adaptation.

Journal: Journal of experimental botany 20111101

Title: Long-term safety and efficacy of fenofibrate/pravastatin combination therapy in high risk patients with mixed hyperlipidemia not controlled by pravastatin monotherapy.

Journal: Current medical research and opinion 20111101

Title: Efficient bioconversion of compactin to pravastatin by the quinoline-degrading microorganism Pseudonocardia carboxydivorans isolated from petroleum-contaminated soil.

Journal: Bioresource technology 20111101

Title: Statins in preventing ventilator-associated pneumonia and death: still only a hope*.

Journal: Critical care medicine 20111101

Title: A cost-benefit analysis of lipid standardization in the United States.

Journal: Preventing chronic disease 20111101

Title: Apolipoprotein B100 is a better treatment target than calculated LDL and non-HDL cholesterol in statin-treated patients.

Journal: Annals of clinical biochemistry 20111101

Title: Statin therapy attenuates growth and malignant potential of human esophageal adenocarcinoma cells.

Journal: The Journal of thoracic and cardiovascular surgery 20111101

Title: Statin therapy for the prevention of atrial fibrillation: a meta-analysis of randomized controlled trials.

Journal: Pharmacotherapy 20111101

Title: Modifiers of symptomatic embolic risk in infective endocarditis.

Journal: Mayo Clinic proceedings 20111101

Title: Lipid lowering drugs and gallstones: a therapeutic option?

Journal: Current pharmaceutical design 20111101

Title: Gender differences, polypharmacy, and potential pharmacological interactions in the elderly.

Journal: Clinics (Sao Paulo, Brazil) 20111101

Title: Pitavastatin: novel effects on lipid parameters.

Journal: Atherosclerosis. Supplements 20111101

Title: The effects of statin and niacin on plaque stability, plaque regression, inflammation and oxidative stress in patients with mild to moderate coronary artery stenosis.

Journal: Korean circulation journal 20111101

Title: Role of lipid rafts in porcine reproductive and respiratory syndrome virus infection in MARC-145 cells.

Journal: Biochemical and biophysical research communications 20111028

Title: High-sensitivity C-reactive protein levels do not decrease with the use of statins in all persons with HIV infection.

Journal: AIDS (London, England) 20111023

Title: Vectorial transport of fexofenadine across Caco-2 cells: involvement of apical uptake and basolateral efflux transporters.

Journal: Molecular pharmaceutics 20111003

Title: NOX1, 2, 4, 5: counting out oxidative stress.

Journal: British journal of pharmacology 20111001

Title: Pravastatin modulates liver bile acid and cholesterol homeostasis in rats with chronic cholestasis.

Journal: Journal of gastroenterology and hepatology 20111001

Title: Circulating interleukin-10 and risk of cardiovascular events: a prospective study in the elderly at risk.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20111001

Title: The discovery of LOX-1, its ligands and clinical significance.

Journal: Cardiovascular drugs and therapy 20111001

Title: Statins inhibit chemotactic interaction between CCL20 and CCR6 in vitro: possible relevance to psoriasis treatment.

Journal: Experimental dermatology 20111001

Title: Genetic testing for early detection of individuals at risk of coronary heart disease and monitoring response to therapy: challenges and promises.

Journal: Current atherosclerosis reports 20111001

Title: Identification of the rate-determining process in the hepatic clearance of atorvastatin in a clinical cassette microdosing study.

Journal: Clinical pharmacology and therapeutics 20111001

Title: Role of complement component C1q in the onset of preeclampsia in mice.

Journal: Hypertension (Dallas, Tex. : 1979) 20111001

Title: Effects of statins on cholestasis: good, bad or indifferent?

Journal: Journal of gastroenterology and hepatology 20111001

Title: Effects of pravastatin on mediators of vascular function in a mouse model of soluble Fms-like tyrosine kinase-1-induced preeclampsia.

Journal: American journal of obstetrics and gynecology 20111001

Title: Smaller Mean LDL Particle Size and Higher Proportion of Small Dense LDL in Korean Type 2 Diabetic Patients.

Journal: Diabetes & metabolism journal 20111001

Title: Are patients undergoing treatment of hyperlipidaemia with statins the best candidates for early cardiac rehabilitation?

Journal: Archives of medical science : AMS 20111001

Title: Effectiveness and tolerability of ezetimibe co-administered with statins versus statin dose-doubling in high-risk patients with persistent hyperlipidemia: The EZE(STAT)2 trial.

Journal: Archives of medical science : AMS 20111001

Title: Safety and impact on cardiovascular events of long-term multifactorial treatment in patients with metabolic syndrome and abnormal liver function tests: a post hoc analysis of the randomised ATTEMPT study.

Journal: Archives of medical science : AMS 20111001

Title: Pravastatin reduces Marfan aortic dilation.

Journal: Circulation 20110913

Title: Differential effect of grapefruit juice on intestinal absorption of statins due to inhibition of organic anion transporting polypeptide and/or P-glycoprotein.

Journal: Journal of pharmaceutical sciences 20110901

Title: Molecular mechanism of vasorelaxant and antiatherogenic effects of the statins in the human saphenous vein graft.

Journal: European journal of pharmacology 20110901

Title: Cardiac remodeling caused by transgenic overexpression of a corn Rac gene.

Journal: American journal of physiology. Heart and circulatory physiology 20110901

Title: Culture period-dependent changes in the uptake of transporter substrates in sandwich-cultured rat and human hepatocytes.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20110901

Title: Low-dose pravastatin and age-related differences in risk factors for cardiovascular disease in hypercholesterolaemic Japanese: analysis of the management of elevated cholesterol in the primary prevention group of adult Japanese (MEGA study).

Journal: Drugs & aging 20110901

Title: Mechanically induced experimental knee osteoarthritis benefits from anti-inflammatory and immunomodulatory properties of simvastatin via inhibition of matrix metalloproteinase-3.

Journal: Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology 20110901

Title: Neurotoxic effect of statins on mouse neuroblastoma NB2a cell line.

Journal: European review for medical and pharmacological sciences 20110901

Title: Comparison of clinical outcomes of hydrophilic and lipophilic statins in patients with acute myocardial infarction.

Journal: The Korean journal of internal medicine 20110901

Title: [Prediction of the pharmacokinetic drug-drug interaction of pravastatin and pitavastatin with cyclosporine by a digital liver model based on metabolism and transporter].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20110901

Title: Challenges in diagnosis of isolated central nervous system vasculitis.

Journal: Brain and behavior 20110901

Title: Graft-protective effects of the HMG-CoA reductase inhibitor pravastatin after lung transplantation--a propensity score analysis with 23 years of follow-up.

Journal: Transplantation 20110827

Title: HMG-CoA reductase inhibitor augments the serum total cholesterol-lowering effect of human adipose tissue-derived multilineage progenitor cells in hyperlipidemic homozygous Watanabe rabbits.

Journal: Biochemical and biophysical research communications 20110819

Title: Disturbed subjective sleep characteristics in adult patients with long-standing type 1 diabetes mellitus.

Journal: Diabetologia 20110801

Title: Long-term follow-up of statin treatment in a cohort of children with familial hypercholesterolemia: efficacy and tolerability.

Journal: Paediatric drugs 20110801

Title: Statins promote the growth of experimentally induced cerebral aneurysms in estrogen-deficient rats.

Journal: Stroke 20110801

Title: HMG-CoA reductase inhibitors enhance phagocytosis by upregulating ATP-binding cassette transporter A7.

Journal: Atherosclerosis 20110801

Title: The complex interplay between cholesterol and prostate malignancy.

Journal: The Urologic clinics of North America 20110801

Title: Lenalidomide in combination with dexamethasone induced rhabdomyolysis in a multiple myeloma patient treated with pravastatin.

Journal: International journal of hematology 20110801

Title: Rosuvastatin prevents proteinuria and renal inflammation in nitric oxide-deficient rats.

Journal: Clinics (Sao Paulo, Brazil) 20110801

Title: Effect of previous statin therapy in patients with acute coronary syndrome and percutaneous coronary intervention.

Journal: Korean circulation journal 20110801

Title: Comparison of different extraction methods for the determination of statin drugs in wastewater and river water by HPLC/Q-TOF-MS.

Journal: Talanta 20110715

Title: Data mining approach shows promise in detecting unexpected drug interactions.

Journal: JAMA 20110713

Title: Effect of pravastatin on cisplatin-induced nephrotoxicity in rats.

Journal: Human & experimental toxicology 20110701

Title: Combination of GSH trapping and time-dependent inhibition assays as a predictive method of drugs generating highly reactive metabolites.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20110701

Title: The statin class of HMG-CoA reductase inhibitors demonstrate differential activation of the nuclear receptors PXR, CAR and FXR, as well as their downstream target genes.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20110701

Title: Ideal lipid profile and genes for an extended life span.

Journal: Current opinion in cardiology 20110701

Title: Pulmonary arterial hypertension and statins: an update.

Journal: Current opinion in cardiology 20110701

Title: Genomic markers to tailor treatments: waiting or initiating?

Journal: Human genetics 20110701

Title: HMG CoA reduction in patients with average cholesterol concentrations.

Journal: Clinical chemistry 20110701

Title: Detecting drug interactions from adverse-event reports: interaction between paroxetine and pravastatin increases blood glucose levels.

Journal: Clinical pharmacology and therapeutics 20110701

Title: Topical anti-inflammatory effect of hypocholesterolaemic drugs.

Journal: The Journal of pharmacy and pharmacology 20110701

Title: Stroke management.

Journal: Annals of Indian Academy of Neurology 20110701

Title: Coronary atherosclerotic plaque rupture following thoracic trauma: an uncommon cause of angina and ventricular tachycardia ('torsade de pointes').

Journal: Clinics (Sao Paulo, Brazil) 20110701

Title: New species in Aspergillus section Terrei.

Journal: Studies in mycology 20110630

Title: [Pharmaco-economic optimization of cholesterol-lowering treatment with statins].

Journal: Medicina clinica 20110625

Title: Intravenous administration of pravastatin immediately after middle cerebral artery occlusion reduces cerebral oedema in spontaneously hypertensive rats.

Journal: European journal of pharmacology 20110625

Title: Effect of statins on cholesterol crystallization and atherosclerotic plaque stabilization.

Journal: The American journal of cardiology 20110615

Title: The effects of lowering LDL cholesterol with simvastatin plus ezetimibe in patients with chronic kidney disease (Study of Heart and Renal Protection): a randomised placebo-controlled trial.

Journal: Lancet (London, England) 20110609

Title: Statins and prostate cancer diagnosis and grade in a veterans population.

Journal: Journal of the National Cancer Institute 20110608

Title: Effects of pravastatin and rosuvastatin on the generation of adiponectin in the visceral adipose tissue in patients with coronary artery disease.

Journal: Fundamental & clinical pharmacology 20110601

Title: Reimbursement of pharmaceuticals: reference pricing versus health technology assessment.

Journal: The European journal of health economics : HEPAC : health economics in prevention and care 20110601

Title: A population-based survey of Chronic REnal Disease In Turkey--the CREDIT study.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20110601

Title: Olmesartan/amlodipine vs olmesartan/hydrochlorothiazide in hypertensive patients with metabolic syndrome: the OLAS study.

Journal: Journal of human hypertension 20110601

Title: High-density lipoprotein (HDL) cholesterol: leveraging practice-based biobank cohorts to characterize clinical and genetic predictors of treatment outcome.

Journal: The pharmacogenomics journal 20110601

Title: Prognostic utility of neopterin and risk of heart failure hospitalization after an acute coronary syndrome.

Journal: European heart journal 20110601

Title: Role of intestinal cytochrome P450 (P450) in modulating the bioavailability of oral lovastatin: insights from studies on the intestinal epithelium-specific P450 reductase knockout mouse.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20110601

Title: Prediction of the overall renal tubular secretion and hepatic clearance of anionic drugs and a renal drug-drug interaction involving organic anion transporter 3 in humans by in vitro uptake experiments.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20110601

Title: Treatment with pravastatin attenuates progression of chronic pancreatitis in rat.

Journal: Laboratory investigation; a journal of technical methods and pathology 20110601

Title: Influence of non-steroidal anti-inflammatory drugs on organic anion transporting polypeptide (OATP) 1B1- and OATP1B3-mediated drug transport.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20110601

Title: Secreted phospholipase A2, lipoprotein hydrolysis, and atherosclerosis: integration with lipidomics.

Journal: Analytical and bioanalytical chemistry 20110601

Title: Effects of statins on matrix metalloproteinases and their endogenous inhibitors in human endothelial cells.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20110601

Title: Decline in low-density lipoprotein cholesterol concentration: lipid-lowering drugs, diet, or physical activity? Evidence from the Whitehall II study.

Journal: Heart (British Cardiac Society) 20110601

Title: Triglyceride-rich lipoproteins and high-density lipoprotein cholesterol in patients at high risk of cardiovascular disease: evidence and guidance for management.

Journal: European heart journal 20110601

Title: Design and in vitro performance evaluation of purified microparticles of pravastatin sodium for intestinal delivery.

Journal: AAPS PharmSciTech 20110601

Title: Assessment of adiponectin and the risk of recurrent cardiovascular events in patients presenting with an acute coronary syndrome: observations from the Pravastatin Or atorVastatin Evaluation and Infection Trial-Thrombolysis in Myocardial Infarction 22 (PROVE IT-TIMI 22).

Journal: American heart journal 20110601

Title: Long-term effects of fosinopril and pravastatin on cardiovascular events in subjects with microalbuminuria:Ten years of follow-up of Prevention of Renal and Vascular End-stage Disease Intervention Trial (PREVEND IT).

Journal: American heart journal 20110601

Title: Effects of D-003 (10 mg/day) on bone mineral density of the lumbar spine and femoral neck in postmenopausal women: a randomized, double-blinded study.

Journal: The Korean journal of internal medicine 20110601

Title: The pathophysiology of chronic graft-versus-host disease: the unveiling of an enigma.

Journal: The Korean journal of hematology 20110601

Title: Antihyperlipidemic activities of Pleurotus ferulae on biochemical and histological function in hypercholesterolemic rats.

Journal: Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences 20110601

Title: Statins, inflammation and kidney disease.

Journal: Nature reviews. Nephrology 20110531

Title: Cascade Screening for Familial Hypercholesterolemia (FH).

Journal: PLoS currents 20110523

Title: High-sensitivity C-reactive protein levels fall during statin therapy in HIV-infected patients receiving ritonavir-boosted protease inhibitors.

Journal: AIDS (London, England) 20110515

Title: Cytotoxic effect of different statins and thiazolidinediones on malignant glioma cells.

Journal: Cancer chemotherapy and pharmacology 20110501

Title: Discovery of novel hepatoselective HMG-CoA reductase inhibitors for treating hypercholesterolemia: a bench-to-bedside case study on tissue selective drug distribution.

Journal: Bioorganic & medicinal chemistry letters 20110501

Title: Host cholesterol synthesis contributes to growth of intracellular Toxoplasma gondii in macrophages.

Journal: The Journal of veterinary medical science 20110501

Title: Effect of statin therapy on disease progression in pediatric ADPKD: design and baseline characteristics of participants.

Journal: Contemporary clinical trials 20110501

Title: The incidence and risk factors for new onset atrial fibrillation in the PROSPER study.

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 20110501

Title: Statins downregulate K6a promoter activity: a possible therapeutic avenue for pachyonychia congenita.

Journal: The Journal of investigative dermatology 20110501

Title: Pravastatin therapy fails to suppress post-PCI inflammatory response measured by serum neopterin and CRP levels.

Journal: Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology 20110501

Title: Noninvasive assessment of atherosclerotic plaque progression in ApoE-/- mice using susceptibility gradient mapping.

Journal: Circulation. Cardiovascular imaging 20110501

Title: Benefit of intensive statin therapy in women: results from PROVE IT-TIMI 22.

Journal: Circulation. Cardiovascular quality and outcomes 20110501

Title: Treatment of indeterminate cell histiocytosis with pravastatin.

Journal: Journal of the American Academy of Dermatology 20110501

Title: Patent extension policy for paediatric indications: an evaluation of the impact within three drug classes in a state Medicaid programme.

Journal: Applied health economics and health policy 20110501

Title: The impact of pravastatin pre-treatment on periprocedural microcirculatory damage in patients undergoing percutaneous coronary intervention.

Journal: JACC. Cardiovascular interventions 20110501

Title: [Research on the effect of statins on insulin secretion from pancreatic islet in rats and its mechanisms].

Journal: Zhonghua nei ke za zhi 20110501

Title: Effects of ezetimibe added to ongoing statin therapy on C-reactive protein levels in hypercholesterolemic patients.

Journal: Korean circulation journal 20110501

Title: Genetic variation in genes involved in folate and drug metabolism in a south Indian population.

Journal: Indian journal of human genetics 20110501

Title: Statin therapy blunts inflammatory activation and improves prognosis and left ventricular performance assessed by Tissue Doppler Imaging in subjects with chronic ischemic heart failure: results from the Daunia Heart Failure Registry.

Journal: Clinics (Sao Paulo, Brazil) 20110501

Title: Rosuvastatin and chronic hepatitis C.

Journal: Hepatitis monthly 20110501

Title: Elevated plasma platelet-activating factor acetylhydrolase activity and its relationship to the presence of coronary artery disease.

Journal: Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences 20110501

Title: Sequential methods for random-effects meta-analysis.

Journal: Statistics in medicine 20110430

Title: Membrane-associated ubiquitin ligase complex containing gp78 mediates sterol-accelerated degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase.

Journal: The Journal of biological chemistry 20110429

Title: Statins potently reduce the cytokine-mediated IL-6 release in SMC/MNC cocultures.

Journal: Journal of cellular and molecular medicine 20110401

Title: The combination of amlodipine and angiotensin receptor blocker or diuretics in high-risk hypertensive patients: rationale, design and baseline characteristics.

Journal: Journal of human hypertension 20110401

Title: An eight-week trial investigating the efficacy and tolerability of atorvastatin for children and adolescents with heterozygous familial hypercholesterolemia.

Journal: Pediatric cardiology 20110401

Title: Obesity is associated with fatal coronary heart disease independently of traditional risk factors and deprivation.

Journal: Heart (British Cardiac Society) 20110401

Title: Statins utilisation pattern: a retrospective evaluation in a tertiary care hospital in Thailand.

Journal: The International journal of pharmacy practice 20110401

Title: Treatment with pravastatin attenuates oxidative stress and protects osteoblast cell viability from indoxyl sulfate.

Journal: Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy 20110401

Title: Pravastatin activates PPARalpha/PPARgamma expression in the liver and gallbladder epithelium of hamsters.

Journal: Hepatobiliary & pancreatic diseases international : HBPD INT 20110401

Title: Strategies and practices in off-label marketing of pharmaceuticals: a retrospective analysis of whistleblower complaints.

Journal: PLoS medicine 20110401

Title: Rosuvastatin and primary cardiovascular prevention. Continue to use pravastatin or simvastatin.

Journal: Prescrire international 20110401

Title: Severe hypertriglyceridaemia during treatment with capecitabine.

Journal: British journal of cancer 20110329

Title: Amelioration of cisplatin-induced nephrotoxicity by pravastatin in mice.

Journal: Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20110301

Title: Variation in the CBP gene involved in epigenetic control associates with cognitive function.

Journal: Neurobiology of aging 20110301

Title: Role of organic cation transporter 1, OCT1 in the pharmacokinetics and toxicity of cis-diammine(pyridine)chloroplatinum(II) and oxaliplatin in mice.

Journal: Pharmaceutical research 20110301

Title: Differential metabolic effects of distinct statins.

Journal: Atherosclerosis 20110301

Title: Influence of long-term treatment with pravastatin on the survival, evolution of cutaneous lesion and weight of animals infected by Leishmania amazonensis.

Journal: Experimental parasitology 20110301

Title: Mannose binding lectin 2 haplotypes do not affect the progression of coronary atherosclerosis in men with proven coronary artery disease treated with pravastatin.

Journal: Atherosclerosis 20110301

Title: Cerebral microbleeds are predictive of mortality in the elderly.

Journal: Stroke 20110301

Title: A novel use of oxidative coupling reactions for determination of some statins (cholesterol-lowering drugs) in pharmaceutical formulations.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20110301

Title: Leptin and beyond: an odyssey to the central control of body weight.

Journal: The Yale journal of biology and medicine 20110301

Title: Depressogenic effects of medications: a review.

Journal: Dialogues in clinical neuroscience 20110301

Title: Comparison of Ezetimibe/Simvastatin 10/20 mg Versus Atorvastatin 20 mg in Achieving a Target Low Density Lipoprotein-Cholesterol Goal for Patients With Very High Risk.

Journal: Korean circulation journal 20110301

Title: [Effect of pravastatin on transportation of scutellarin in mouse liver and its mechanism].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20110301

Title: Low-density lipoprotein cholesterol goal attainment among Malaysian dyslipidemic patients.

Journal: The Southeast Asian journal of tropical medicine and public health 20110301

Title: More powerful search engine invalidates anonymity guidelines for case reports.

Journal: Healthcare informatics research 20110301

Title: Efficacy and safety of more intensive lowering of LDL cholesterol.

Journal: Lancet (London, England) 20110226

Title: C-reactive protein concentration and the vascular benefits of statin therapy: an analysis of 20,536 patients in the Heart Protection Study.

Journal: Lancet (London, England) 20110205

Title: Effect of niacin on preβ-1 high-density lipoprotein levels in diabetes.

Journal: Metabolism: clinical and experimental 20110201

Title: Potential mechanisms of hypocholesterolaemic effect of Thai spices/dietary extracts.

Journal: Natural product research 20110201

Title: Statin therapy in metabolic syndrome and hypertension post-JUPITER: what is the value of CRP?

Journal: Current atherosclerosis reports 20110201

Title: Subtrochanteric fractures after long-term treatment with bisphosphonates: a European Society on Clinical and Economic Aspects of Osteoporosis and Osteoarthritis, and International Osteoporosis Foundation Working Group Report.

Journal: Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 20110201

Title: What combination therapy with a statin, if any, would you recommend?

Journal: Current atherosclerosis reports 20110201

Title: The anti-ischemic and anti-anginal properties of statins.

Journal: Current atherosclerosis reports 20110201

Title: Antithrombotic properties of pravastatin reducing intra-thrombus fibrin deposition under high shear blood flow conditions.

Journal: Thrombosis and haemostasis 20110201

Title: Achievement of lipid targets with the combination of rosuvastatin and fenofibric Acid in patients with type 2 diabetes mellitus.

Journal: Cardiovascular drugs and therapy 20110201

Title: Approach to dyslipidemia, lipodystrophy, and cardiovascular risk in patients with HIV infection.

Journal: Current atherosclerosis reports 20110201

Title: Comparative Effectiveness and Toxicity of Statins Among HIV-Infected Patients.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20110201

Title: Role of tissue factor in pregnancy complications: crosstalk between coagulation and inflammation.

Journal: Thrombosis research 20110201

Title: [Genetic marker of statin-induced rhabdomyolysis].

Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20110201

Title: Assessment of coronary atherosclerosis by IVUS and IVUS-based imaging modalities: progression and regression studies, tissue composition and beyond.

Journal: The international journal of cardiovascular imaging 20110201

Title: Long-term efficacy of adding fenofibric acid to moderate-dose statin therapy in patients with persistent elevated triglycerides.

Journal: Cardiovascular drugs and therapy 20110201

Title: [Pravastatin and rosiglitazone combination therapy upgrades the expression of ABCA1 in THP-1 macrophages].

Journal: Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 20110201

Title: [Retention behavior of statins in microemulsion liquid chromatography].

Journal: Se pu = Chinese journal of chromatography 20110201

Title: Rosuvastatin reduces nonalcoholic fatty liver disease in patients with chronic hepatitis C treated with α-interferon and ribavirin: Rosuvastatin reduces NAFLD in HCV patients.

Journal: Hepatitis monthly 20110201

Title: World Kidney Day 2011 - Protect your kidneys, save your heart.

Journal: Archives of medical science : AMS 20110201

Title: The statins fluvastatin and pravastatin exert anti-flushing effects by improving vasomotor dysfunction through nitric oxide-mediated mechanisms in ovariectomized animals.

Journal: European journal of pharmacology 20110125

Title: Monitoring adherence to drug treatment by using change in cholesterol concentration: secondary analysis of trial data.

Journal: BMJ (Clinical research ed.) 20110121

Title: Construction of a novel expression vector in Pseudonocardia autotrophica and its application to efficient biotransformation of compactin to pravastatin, a specific HMG-CoA reductase inhibitor.

Journal: Biochemical and biophysical research communications 20110107

Title: Genetic variants in the KIF6 region and coronary event reduction from statin therapy.

Journal: Human genetics 20110101

Title: Pravastatin normalises peripheral cardiac sympathetic hyperactivity in the spontaneously hypertensive rat.

Journal: Journal of molecular and cellular cardiology 20110101

Title: Differential effects of statins on endogenous H2S formation in perivascular adipose tissue.

Journal: Pharmacological research 20110101

Title: Use of ultra high performance liquid chromatography-tandem mass spectrometry to demonstrate decreased serum statin levels after extracorporeal LDL-cholesterol elimination.

Journal: Journal of biomedicine & biotechnology 20110101

Title: The fat-fed apolipoprotein E knockout mouse brachiocephalic artery in the study of atherosclerotic plaque rupture.

Journal: Journal of biomedicine & biotechnology 20110101

Title: Statin treatment decreased serum asymmetric dimethylarginine (ADMA) levels in ischemic stroke patients.

Journal: Journal of atherosclerosis and thrombosis 20110101

Title: Statins as neuroprotectants: a comparative in vitro study of lipophilicity, blood-brain-barrier penetration, lowering of brain cholesterol, and decrease of neuron cell death.

Journal: Journal of Alzheimer's disease : JAD 20110101

Title: Paradoxical decrease in HDL-cholesterol and apolipoprotein A1 with simvastatin and atorvastatin in a patient with type 2 diabetes.

Journal: Annals of clinical biochemistry 20110101

Title: Colchicine-induced rhabdomyolysis in a heart/lung transplant patient with concurrent use of cyclosporin, pravastatin, and azithromycin.

Journal: Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases 20110101

Title: Statins have an early antiplatelet effect in patients with acute myocardial infarction.

Journal: Platelets 20110101

Title: Standards of medical care in diabetes--2011.

Journal: Diabetes care 20110101

Title: Proximal tubule cell hypothesis for cardiorenal syndrome in diabetes.

Journal: International journal of nephrology 20110101

Title: Simvastatin is the statin that most efficiently protects against kainate-induced excitotoxicity and memory impairment.

Journal: Journal of Alzheimer's disease : JAD 20110101

Title: [Anti-atherosclerotic and anti-inflammatory effects of statin on cardiovascular disease and their mechanisms].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20110101

Title: Study design and rationale of 'Synergistic effect of combination therapy with cilostazol and ProbUcol on plaque stabilization and lesion REgression (SECURE)' study: a double-blind randomised controlled multicenter clinical trial.

Journal: Trials 20110101

Title: The proprotein convertase subtilisin/kexin type 9 gene E670G polymorphism and serum lipid levels in the Guangxi Bai Ku Yao and Han populations.

Journal: Lipids in health and disease 20110101

Title: Understanding diabetes in patients with HIV/AIDS.

Journal: Diabetology & metabolic syndrome 20110101

Title: Internet-based treatment for older adults with depression and co-morbid cardiovascular disease: protocol for a randomised, double-blind, placebo controlled trial.

Journal: BMC psychiatry 20110101

Title: ADPKD: Prototype of Cardiorenal Syndrome Type 4.

Journal: International journal of nephrology 20110101

Title: Transforming Growth Factor-β1 as a Common Target Molecule for Development of Cardiovascular Diseases, Renal Insufficiency and Metabolic Syndrome.

Journal: Cardiology research and practice 20110101

Title: NeOProM: Neonatal Oxygenation Prospective Meta-analysis Collaboration study protocol.

Journal: BMC pediatrics 20110101

Title: Novel adiponectin-resistin (AR) and insulin resistance (IRAR) indexes are useful integrated diagnostic biomarkers for insulin resistance, type 2 diabetes and metabolic syndrome: a case control study.

Journal: Cardiovascular diabetology 20110101

Title: The development and the use of experimental animal models to study the underlying mechanisms of CA formation.

Journal: Journal of biomedicine & biotechnology 20110101

Title: Lipoprotein-associated phospholipase A2 mass and activity in children with heterozygous familial hypercholesterolemia and unaffected siblings: effect of pravastatin.

Journal: Journal of clinical lipidology 20110101

Title: Pharmacological and non-pharmacological interventions to influence adipose tissue function.

Journal: Cardiovascular diabetology 20110101

Title: Pre-procedural atorvastatin mobilizes endothelial progenitor cells: clues to the salutary effects of statins on healing of stented human arteries.

Journal: PloS one 20110101

Title: Large-scale candidate gene analysis of HDL particle features.

Journal: PloS one 20110101

Title: Effect of chemokine receptor CXCR4 on hypoxia-induced pulmonary hypertension and vascular remodeling in rats.

Journal: Respiratory research 20110101

Title: Relative survival: a useful tool to assess generalisability in longitudinal studies of health in older persons.

Journal: Emerging themes in epidemiology 20110101

Title: Functional promoter polymorphisms govern differential expression of HMG-CoA reductase gene in mouse models of essential hypertension.

Journal: PloS one 20110101

Title: Adiponectin provides cardiovascular protection in metabolic syndrome.

Journal: Cardiology research and practice 20110101

Title: Cardiovascular prevention of cognitive decline.

Journal: Cardiology research and practice 20110101

Title: Formation of Toxic Amyloid Fibrils by Amyloid β-Protein on Ganglioside Clusters.

Journal: International journal of Alzheimer's disease 20110101

Title: Restoration of cognitive deficits after statin feeding in TBI.

Journal: Restorative neurology and neuroscience 20110101

Title: Considering statins for cholesterol-reduction in children if lifestyle and diet changes do not improve their health: a review of the risks and benefits.

Journal: Vascular health and risk management 20110101

Title: ACE up the sleeve - are vascular patients medically optimized?

Journal: Vascular health and risk management 20110101

Title: Incident venous thromboembolic events in the Prospective Study of Pravastatin in the Elderly at Risk (PROSPER).

Journal: BMC geriatrics 20110101

Title: Glucose-lowering effect of colestimide is associated with baseline HbA1c in type 2 diabetic patients with hypercholesterolemia.

Journal: Endocrine journal 20110101

Title: Statins do not prevent acute organ failure in ventilated ICU patients: single-centre retrospective cohort study.

Journal: Critical care (London, England) 20110101

Title: Atorvastatin prevents Plasmodium falciparum cytoadherence and endothelial damage.

Journal: Malaria journal 20110101

Title: Effect of atorvastatin and clopidogrel co-administration after coronary stenting in korean patients with stable angina.

Journal: Korean circulation journal 20110101

Title: An effective assessment of simvastatin-induced toxicity with NMR-based metabonomics approach.

Journal: PloS one 20110101

Title: Pravastatin versus simvastatin for prevention of contrast-induced nephropathy.

Journal: Journal of cardiovascular pharmacology and therapeutics 20110101

Title: Fixed-dose combination fenofibrate/pravastatin 160/40 mg versus simvastatin 20 mg monotherapy in adults with type 2 diabetes and mixed hyperlipidemia uncontrolled with simvastatin 20 mg: a double-blind, randomized comparative study.

Journal: Clinical therapeutics 20110101

Title: Animal models of cardiovascular diseases.

Journal: Journal of biomedicine & biotechnology 20110101

Title: Association between serum soluble CD40 ligand levels and mortality in patients with severe sepsis.

Journal: Critical care (London, England) 20110101

Title: Residual beta cell function in newly diagnosed type 1 diabetes after treatment with atorvastatin: the Randomized DIATOR Trial.

Journal: PloS one 20110101

Title: Acute-phase proteins: As diagnostic tool.

Journal: Journal of pharmacy & bioallied sciences 20110101

Title: Survival bias and drug interaction can attenuate cross-sectional case-control comparisons of genes with health outcomes. An example of the kinesin-like protein 6 (KIF6) Trp719Arg polymorphism and coronary heart disease.

Journal: BMC medical genetics 20110101

Title: Statins as modulators of colon cancer cells induced cytokine secretion by human PBMC.

Journal: Vascular pharmacology 20110101

Title: Are all statins the same? Focus on the efficacy and tolerability of pitavastatin.

Journal: American journal of cardiovascular drugs : drugs, devices, and other interventions 20110101

Title: Characterization of human erythrocytes as potential carrier for pravastatin: an in vitro study.

Journal: International journal of medical sciences 20110101

Title: Apolipoprotein E epsilon-4 polymorphism is associated with younger age at referral to a lipidology clinic and a poorer response to lipid-lowering therapy.

Journal: Lipids in health and disease 20110101

Title: Design of cohort studies in chronic diseases using routinely collected databases when a prescription is used as surrogate outcome.

Journal: BMC medical research methodology 20110101

Title: Statins: cardiovascular risk reduction in percutaneous coronary intervention-basic and clinical evidence of hyperacute use of statins.

Journal: International journal of hypertension 20110101

Title: Metabolic syndrome and renal injury.

Journal: Cardiology research and practice 20110101

Title: Structure modeling and inhibitor prediction ofNADP oxidoreductase enzyme from Methanobrevibacter smithii.

Journal: Bioinformation 20110101

Title: Effect of statin treatment on short term mortality after pneumonia episode: cohort study.

Journal: BMJ (Clinical research ed.) 20110101

Title: Clinical utility of rosuvastatin and other statins for cardiovascular risk reduction among the elderly.

Journal: Clinical interventions in aging 20110101

Title: Effects of short-term treatment with atorvastatin in smokers with asthma--a randomized controlled trial.

Journal: BMC pulmonary medicine 20110101

Title: ATP-binding cassette transporter A1 gene polymorphisms and serum lipid levels in young Greek nurses.

Journal: Lipids in health and disease 20110101

Title: A new pathway of glucocorticoid action for asthma treatment through the regulation of PTEN expression.

Journal: Respiratory research 20110101

Title: Carriage of the V279F null allele within the gene encoding Lp-PLA₂ is protective from coronary artery disease in South Korean males.

Journal: PloS one 20110101

Title: Doppler study of cerebral arteries in hypercholesterolemia.

Journal: Vascular health and risk management 20110101

Title: BICEPP: an example-based statistical text mining method for predicting the binary characteristics of drugs.

Journal: BMC bioinformatics 20110101

Title: Pitavastatin increases ABCA1 expression by dual mechanisms: SREBP2-driven transcriptional activation and PPARα-dependent protein stabilization but without activating LXR in rat hepatoma McARH7777 cells.

Journal: Journal of pharmacological sciences 20110101

Title: Simvastatin suppresses dexamethasone-induced secretion of plasminogen activator inhibitor-1 in human bone marrow adipocytes.

Journal: BMC musculoskeletal disorders 20110101

Title: Serum lipoprotein levels in takotsubo cardiomyopathy vs. myocardial infarction.

Journal: International archives of medicine 20110101

Title: Acute modulation of vasoconstrictor responses by pravastatin in small vessels.

Journal: Circulation journal : official journal of the Japanese Circulation Society 20110101

Title: Pre-admission statin use and in-hospital severity of 2009 pandemic influenza A(H1N1) disease.

Journal: PloS one 20110101

Title: Urinary elimination of coproporphyrins is dependent on ABCC2 polymorphisms and represents a potential biomarker of MRP2 activity in humans.

Journal: Journal of biomedicine & biotechnology 20110101

Title: Roles of the WHHL rabbit in translational research on hypercholesterolemia and cardiovascular diseases.

Journal: Journal of biomedicine & biotechnology 20110101

Title: Globular adiponectin, acting via AdipoR1/APPL1, protects H9c2 cells from hypoxia/reoxygenation-induced apoptosis.

Journal: PloS one 20110101

Title: Rhabdomyolysis in an HIV-infected patient with impaired renal function concomitantly treated with rosuvastatin and lopinavir/ritonavir.

Journal: Antiviral therapy 20110101

Title: Pleiotropic effects of the HMG-CoA reductase inhibitors.

Journal: International journal of general medicine 20110101

Title: Clinical use and effectiveness of lipid lowering therapies in diabetes mellitus--an observational study from the Swedish National Diabetes Register.

Journal: PloS one 20110101

Title: Memory loss, behavioral changes, and slurred speech in a 49-year-old man.

Journal: Frontiers in neurology 20110101

Title: Genetic background of patients from a university medical center in Manhattan: implications for personalized medicine.

Journal: PloS one 20110101

Title: Increased serum myeloid-related protein 8/14 level is associated with atherosclerosis in type 2 diabetic patients.

Journal: Cardiovascular diabetology 20110101

Title: No connection between the level of exposition to statins in the population and the incidence/mortality of acute myocardial infarction: an ecological study based on Sweden's municipalities.

Journal: Journal of negative results in biomedicine 20110101

Title: Cardioprotective effects of pravastatin against lethal ventricular arrhythmias induced by reperfusion in the rat heart.

Journal: Circulation journal : official journal of the Japanese Circulation Society 20110101

Title: Place of pitavastatin in the statin armamentarium: promising evidence for a role in diabetes mellitus.

Journal: Drug design, development and therapy 20110101

Title: Concomitant use of simvastatin and amiodarone resulting in severe rhabdomyolysis: a case report and review of the literature.

Journal: Acta clinica Belgica 20110101

Title: A current evaluation of the safety of angiotensin receptor blockers and direct renin inhibitors.

Journal: Vascular health and risk management 20110101

Title: High throughput ratio imaging to profile caspase activity: potential application in multiparameter high content apoptosis analysis and drug screening.

Journal: PloS one 20110101

Title: Peripheral vascular dysfunction in chronic kidney disease.

Journal: Cardiology research and practice 20110101

Title: Dyslipidemia associated with chronic kidney disease.

Journal: The open cardiovascular medicine journal 20110101

Title: HIV and HAART-Associated Dyslipidemia.

Journal: The open cardiovascular medicine journal 20110101

Title: Mechanism of AMPK suppression of LXR-dependent Srebp-1c transcription.

Journal: International journal of biological sciences 20110101

Title: Orange juice and its component, hesperidin, decrease the expression of multidrug resistance-associated protein 2 in rat small intestine and liver.

Journal: Journal of biomedicine & biotechnology 20110101

Title: Dyslipidaemia in rheumatological autoimmune diseases.

Journal: The open cardiovascular medicine journal 20110101

Title: Dyslipidaemia of obesity, metabolic syndrome and type 2 diabetes mellitus: the case for residual risk reduction after statin treatment.

Journal: The open cardiovascular medicine journal 20110101

Title: Buffy coat specimens remain viable as a DNA source for highly multiplexed genome-wide genetic tests after long term storage.

Journal: Journal of translational medicine 20110101

Title: Clinical characteristics and evaluation of LDL-cholesterol treatment of the Spanish Familial Hypercholesterolemia Longitudinal Cohort Study (SAFEHEART).

Journal: Lipids in health and disease 20110101

Title: A post-trial survey to assess the impact of dissemination of results and unmasking on participants in a 13-year randomised controlled trial on age-related cataract.

Journal: Trials 20110101

Title: Comparison of preventive effect on cardiovascular events with different statins. -The CIRCLE study-.

Journal: Circulation journal : official journal of the Japanese Circulation Society 20110101

Title: Immunological and cardiometabolic risk factors in the prediction of type 2 diabetes and coronary events: MONICA/KORA Augsburg case-cohort study.

Journal: PloS one 20110101

Title: The effect of cardiovascular risk factors on the longitudinal evolution of the carotid intima medial thickness in children with type 1 diabetes mellitus.

Journal: Cardiovascular diabetology 20110101

Title: The chronic kidney disease model: a general purpose model of disease progression and treatment.

Journal: BMC medical informatics and decision making 20110101

Title: Internalization of Escherichia coli o157:h7 by bovine rectal epithelial cells.

Journal: Frontiers in microbiology 20110101

Title: Potential involvement of LOX-1 in functional consequences of endothelial senescence.

Journal: PloS one 20110101

Title: Renal function at the time of a myocardial infarction maintains prognostic value for more than 10 years.

Journal: BMC cardiovascular disorders 20110101

Title: Effects of HMG-CoA reductase inhibitors on the pharmacokinetics of losartan and its main metabolite EXP-3174 in rats: possible role of CYP3A4 and P-gp inhibition by HMG-CoA reductase inhibitors.

Journal: Pharmacology 20110101

Title: Pitavastatin suppresses diethylnitrosamine-induced liver preneoplasms in male C57BL/KsJ-db/db obese mice.

Journal: BMC cancer 20110101

Title: Relationship between hemoglobin A1c and cardiovascular disease in mild-to-moderate hypercholesterolemic Japanese individuals: subanalysis of a large-scale randomized controlled trial.

Journal: Cardiovascular diabetology 20110101

Title: Leptin in teleost fishes: an argument for comparative study.

Journal: Frontiers in physiology 20110101

Title: Antihypertriglyceridemia and anti-inflammatory activities of monascus-fermented dioscorea in streptozotocin-induced diabetic rats.

Journal: Experimental diabetes research 20110101

Title: Association of statin therapy with blood pressure control in hypertensive hypercholesterolemic outpatients in clinical practice.

Journal: Journal of cardiovascular disease research 20110101

Title: Generation of polyclonal antibody with high avidity to rosuvastatin and its use in development of highly sensitive ELISA for determination of rosuvastatin in plasma.

Journal: Chemistry Central journal 20110101

Title: Insulin-regulated Srebp-1c and Pck1 mRNA expression in primary hepatocytes from zucker fatty but not lean rats is affected by feeding conditions.

Journal: PloS one 20110101

Title: Effect of atorvastatin therapy on oxidant-antioxidant status and atherosclerotic plaque formation.

Journal: Vascular health and risk management 20110101

Title: Circulating adiponectin levels are lower in Latino versus non-Latino white patients at risk for cardiovascular disease, independent of adiposity measures.

Journal: BMC endocrine disorders 20110101

Title: The impact of hypertension on patients with acute coronary syndromes.

Journal: International journal of hypertension 20110101

Title: Association between use of HMG CoA reductase inhibitors and mortality in HIV-infected patients.

Journal: PloS one 20110101

Title: Dyslipidemia induced by drugs used for the prevention and treatment of vascular diseases.

Journal: The open cardiovascular medicine journal 20110101

Title: Influence of atorvastatin on coronary calcifications and myocardial perfusion defects in systemic lupus erythematosus patients: a prospective, randomized, double-masked, placebo-controlled study.

Journal: Arthritis research & therapy 20110101

Title: Treating statin-intolerant patients.

Journal: Diabetes, metabolic syndrome and obesity : targets and therapy 20110101

Title: Clinical therapeutics in pregnancy.

Journal: Journal of biomedicine & biotechnology 20110101

Title: Factor VII Activating Protease Polymorphism (G534E) Is Associated with Increased Risk for Stroke and Mortality.

Journal: Stroke research and treatment 20110101

Title: Adherence with statins in a real-life setting is better when associated cardiovascular risk factors increase: a cohort study.

Journal: BMC cardiovascular disorders 20110101

Title: Primary prevention of coronary heart disease: integration of new data, evolving views, revised goals, and role of rosuvastatin in management. A comprehensive survey.

Journal: Drug design, development and therapy 20110101

Title: Optimal therapeutic strategy for treating patients with hypertension and atherosclerosis: focus on olmesartan medoxomil.

Journal: Vascular health and risk management 20110101

Title: Carotid plaque regression following 6-month statin therapy assessed by 3T cardiovascular magnetic resonance: comparison with ultrasound intima media thickness.

Journal: Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance 20110101

Title: Accumulation and aberrant composition of cholesteryl esters in Scrapie-infected N2a cells and C57BL/6 mouse brains.

Journal: Lipids in health and disease 20110101

Title: Mesenchymal stem cell transplantation ameliorates motor function deterioration of spinocerebellar ataxia by rescuing cerebellar Purkinje cells.

Journal: Journal of biomedical science 20110101

Title: Transport characteristics of tryptanthrin and its inhibitory effect on P-gp and MRP2 in Caco-2 cells.

Journal: Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20110101

Title: Anti-inflammatory effect of fluvastatin on IL-8 production induced by Pseudomonas aeruginosa and Aspergillus fumigatus antigens in cystic fibrosis.

Journal: PloS one 20110101

Title: Comparative effect of olmesartan and candesartan on lipid metabolism and renal function in patients with hypertension: a retrospective observational study.

Journal: Cardiovascular diabetology 20110101

Title: Antihyperlipidemic effects of Pleurotus ostreatus (oyster mushrooms) in HIV-infected individuals taking antiretroviral therapy.

Journal: BMC complementary and alternative medicine 20110101

Title: Inflammatory concepts of obesity.

Journal: International journal of inflammation 20110101

Title: A systems biology strategy for predicting similarities and differences of drug effects: evidence for drug-specific modulation of inflammation in atherosclerosis.

Journal: BMC systems biology 20110101

Title: Tacrolimus and 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors: An interaction study in CYP3A5 non-expressors, renal transplant recipients.

Journal: Indian journal of pharmacology 20110101

Title: Comparison of nebivolol and atenolol on blood pressure, blood sugar, and lipid profile in patients of essential hypertension.

Journal: Indian journal of pharmacology 20110101

Title: ATP-Sensitive Potassium Channel Currents in Eccentrically Hypertrophied Cardiac Myocytes of Volume-Overloaded Rats.

Journal: International journal of cell biology 20110101

Title: Response by sex to statin plus ezetimibe or statin monotherapy: a pooled analysis of 22,231 hyperlipidemic patients.

Journal: Lipids in health and disease 20110101

Title: Simvastatin inhibits TGFβ1-induced fibronectin in human airway fibroblasts.

Journal: Respiratory research 20110101

Title: Treatment of allergic asthma: modulation of Th2 cells and their responses.

Journal: Respiratory research 20110101

Title: Age-related white matter changes.

Journal: Journal of aging research 20110101

Title: Myeloid-related protein activity in rheumatoid arthritis.

Journal: International journal of inflammation 20110101

Title: Trends in the Use of Evidence-based Therapies Early in the Course of Acute Myocardial Infarction and its Influence on Short Term Patient Outcomes.

Journal: The open cardiovascular medicine journal 20110101

Title: Incidence of pancreatitis, secondary causes, and treatment of patients referred to a specialty lipid clinic with severe hypertriglyceridemia: a retrospective cohort study.

Journal: Lipids in health and disease 20110101

Title: Inhibition of lipoprotein-associated phospholipase A2 ameliorates inflammation and decreases atherosclerotic plaque formation in ApoE-deficient mice.

Journal: PloS one 20110101

Title: Studies on the antibacterial effects of statins--in vitro and in vivo.

Journal: PloS one 20110101

Title: Lipid-lowering therapy: who can benefit?

Journal: Vascular health and risk management 20110101

Title: Clinical characteristics and outcomes of patients with acute coronary syndrome and prior coronary artery bypass grafting in a large middle eastern cohort.

Journal: The open cardiovascular medicine journal 20110101

Title: C-reactive protein and genetic variants and cognitive decline in old age: the PROSPER study.

Journal: PloS one 20110101

Title: No evidence for statin-induced proteinuria in healthy volunteers as assessed by proteomic analysis.

Journal: Journal of biomedicine & biotechnology 20110101

Title: APPROACH-J study: design, rationale, and baseline data of the affirmation primary prevention with pravastatin in reduction of occlusive atherosclerotic complications in hypercholesterolemia--Japan study.

Journal: Journal of atherosclerosis and thrombosis 20110101

Title: Statins enhance clonal growth of late outgrowth endothelial progenitors and increase myocardial capillary density in the chronically ischemic heart.

Journal: PloS one 20110101

Title: Observational study of lipid profile and LDL particle size in patients with metabolic syndrome.

Journal: Lipids in health and disease 20110101

Title: Tissue factor, blood coagulation, and beyond: an overview.

Journal: International journal of inflammation 20110101

Title: Exposure to statins and risk of common cancers: a series of nested case-control studies.

Journal: BMC cancer 20110101

Title: Administration of simvastatin after kainic acid-induced status epilepticus restrains chronic temporal lobe epilepsy.

Journal: PloS one 20110101

Title: Antioxidant and inflammatory aspects of lipoprotein-associated phospholipase A₂ (Lp-PLA₂): a review.

Journal: Lipids in health and disease 20110101

Title: A retrospective cohort study of the potency of lipid-lowering therapy and race-gender differences in LDL cholesterol control.

Journal: BMC cardiovascular disorders 20110101

Title: The effect of the addition of resistance training to a dietary education intervention on apolipoproteins and diet quality in overweight and obese older adults.

Journal: Clinical interventions in aging 20110101

Title: Imaging of zebrafish in vivo with second-harmonic generation reveals shortened sarcomeres associated with myopathy induced by statin.

Journal: PloS one 20110101

Title: Replication of LDL GWAs hits in PROSPER/PHASE as validation for future (pharmaco)genetic analyses.

Journal: BMC medical genetics 20110101

Title: Age, gender, insulin and blood glucose control status alter the risk of ischemic heart disease and stroke among elderly diabetic patients.

Journal: Cardiovascular diabetology 20110101

Title: Atorvastatin therapy during the peri-infarct period attenuates left ventricular dysfunction and remodeling after myocardial infarction.

Journal: PloS one 20110101

Title: Emerging therapeutic strategies to enhance HDL function.

Journal: Lipids in health and disease 20110101

Title: Effectiveness of Ezetimibe in Reducing the Estimated Risk for Fatal Cardiovascular Events in Hypercholesterolaemic Patients with Inadequate Lipid Control While on Statin Monotherapy as Measured by the SCORE Model.

Journal: Advances in preventive medicine 20110101

Title: Suppression of nitric oxide induction and pro-inflammatory cytokines by novel proteasome inhibitors in various experimental models.

Journal: Lipids in health and disease 20110101

Title: SLCO1B1 rs4149056 polymorphism associated with statin-induced myopathy is differently distributed according to ethnicity in the Brazilian general population: Amerindians as a high risk ethnic group.

Journal: BMC medical genetics 20110101

Title: Pleiotropic effects of statins in distal human pulmonary artery smooth muscle cells.

Journal: Respiratory research 20110101

Title: Challenges associated with tyrosine kinase inhibitor therapy for metastatic thyroid cancer.

Journal: Journal of thyroid research 20110101

Title: Pharmacogenetics of OATP transporters reveals that SLCO1B1 c.388A>G variant is determinant of increased atorvastatin response.

Journal: International journal of molecular sciences 20110101

Title: Enteric microbiome metabolites correlate with response to simvastatin treatment.

Journal: PloS one 20110101

Title: Effects of atorvastatin and rosuvastatin on high-sensitivity C-reactive protein and lipid profile in obese type 2 diabetes mellitus patients.

Journal: Journal of pharmacology & pharmacotherapeutics 20110101

Title: South Asian Consensus Guidelines for the rational management of diabetes in human immunodeficiency virus/acquired immunodeficiency syndrome.

Journal: Indian journal of endocrinology and metabolism 20110101

Title: Estimated glomerular filtration rate and the risk of major vascular events and all-cause mortality: a meta-analysis.

Journal: PloS one 20110101

Title: Takotsubo cardiomyopathy after a dancing session: a case report.

Journal: Journal of medical case reports 20110101

Title: Prognostic effect size of cardiovascular biomarkers in datasets from observational studies versus randomised trials: meta-epidemiology study.

Journal: BMJ (Clinical research ed.) 20110101

Title: Camphene, a plant-derived monoterpene, reduces plasma cholesterol and triglycerides in hyperlipidemic rats independently of HMG-CoA reductase activity.

Journal: PloS one 20110101

Title: Apolipoprotein E mRNA expression in mononuclear cells from normolipidemic and hypercholesterolemic individuals treated with atorvastatin.

Journal: Lipids in health and disease 20110101

Title: Recognition of morphometric vertebral fractures by artificial neural networks: analysis from GISMO Lombardia Database.

Journal: PloS one 20110101

Title: Simvastatin protects auditory hair cells from gentamicin-induced toxicity and activates Akt signaling in vitro.

Journal: BMC neuroscience 20110101

Title: Safety and efficacy of dronedarone in the treatment of atrial fibrillation/flutter.

Journal: Clinical Medicine Insights. Cardiology 20110101

Title: Apolipoprotein A-I and A-I mimetic peptides: a role in atherosclerosis.

Journal: Journal of inflammation research 20110101

Title: Vascular involvement in systemic sclerosis (scleroderma).

Journal: Journal of inflammation research 20110101

Title: Role of raltegravir in the management of HIV-1 infection.

Journal: HIV/AIDS (Auckland, N.Z.) 20110101

Title: Decreased glomerular filtration rate is associated with mortality and cardiovascular events in patients with hypertension: a prospective study.

Journal: PloS one 20110101

Title: Distinct effects of acute pretreatment with lipophilic and hydrophilic statins on myocardial stunning, arrhythmias and lethal injury in the rat heart subjected to ischemia/reperfusion.

Journal: Physiological research 20110101

Title: Nicorandil prevents endothelial dysfunction due to antioxidative effects via normalisation of NADPH oxidase and nitric oxide synthase in streptozotocin diabetic rats.

Journal: Cardiovascular diabetology 20110101

Title: Adaptation to statins restricts human tumour growth in Nude mice.

Journal: BMC cancer 20110101

Title: Acute myocardial infarction in young adults with antiphospholipid syndrome: report of two cases and literature review.

Journal: The Pan African medical journal 20110101

Title: Statins and prevention of infections: systematic review and meta-analysis of data from large randomised placebo controlled trials.

Journal: BMJ (Clinical research ed.) 20110101

Title: Enhancement of lutein production in Chlorella sorokiniana (Chorophyta) by improvement of culture conditions and random mutagenesis.

Journal: Marine drugs 20110101

Title: Gene-drug interaction in stroke.

Journal: Stroke research and treatment 20110101

Title: Current state of cardiac rehabilitation in Germany: patient characteristics, risk factor management and control status, by education level.

Journal: Vascular health and risk management 20110101

Title: Peroxisome proliferator-activated receptor-gamma agonists suppress tissue factor overexpression in rat balloon injury model with paclitaxel infusion.

Journal: PloS one 20110101

Title: Molecular diagnosis of analbuminemia: a new case caused by a nonsense mutation in the albumin gene.

Journal: International journal of molecular sciences 20110101

Title: Medical angioplasty - hope and expectations: an optimistic overview.

Journal: Journal of family & community medicine 20110101

Title: Inhibition of nitric oxide in LPS-stimulated macrophages of young and senescent mice by δ-tocotrienol and quercetin.

Journal: Lipids in health and disease 20110101

Title: [Therapeutic use Hibiscus sabadariffa extract in the treatment of hypercholesterolemia. A randomized clinical trial].

Journal: Revista medica del Instituto Mexicano del Seguro Social 20110101

Title: Long-term efficacy of upstream therapy with lipophilic or hydrophilic statins on antiarrhythmic drugs in patients with paroxysmal atrial fibrillation: comparison between atorvastatin and pravastatin.

Journal: International heart journal 20110101

Title: Assessment of monacolin in the fermented products using Monascus purpureus FTC5391.

Journal: Journal of biomedicine & biotechnology 20110101

Title: Protective Effects of Simvastatin, a Lipid Lowering Agent, against Oxidative Damage in Experimental Diabetic Rats.

Journal: Journal of lipids 20110101

Title: Cholesterol, C-Reactive Protein, and Periodontitis: HMG-CoA-Reductase Inhibitors (Statins) as Effect Modifiers.

Journal: ISRN dentistry 20110101

Title: Systematic drug repositioning based on clinical side-effects.

Journal: PloS one 20110101

Title: Statin-associated muscular and renal adverse events: data mining of the public version of the FDA adverse event reporting system.

Journal: PloS one 20110101

Title: The dynamin chemical inhibitor dynasore impairs cholesterol trafficking and sterol-sensitive genes transcription in human HeLa cells and macrophages.

Journal: PloS one 20110101

Title: Preventing Cardio-renal Syndrome Rather than Treating It: Could Statins Play A Role?

Journal: The open cardiovascular medicine journal 20110101

Title: Differential effects of pravastatin and simvastatin on the growth of tumor cells from different organ sites.

Journal: PloS one 20110101

Title: A common KIF6 polymorphism increases vulnerability to low-density lipoprotein cholesterol: two meta-analyses and a meta-regression analysis.

Journal: PloS one 20110101

Title: Lipodystrophy in HIV patients: its challenges and management approaches.

Journal: HIV/AIDS (Auckland, N.Z.) 20110101

Title: Efficacy and safety of gonadotropin-releasing hormone agonists used in the treatment of prostate cancer.

Journal: Drug, healthcare and patient safety 20110101

Title: Mthfs is an Essential Gene in Mice and a Component of the Purinosome.

Journal: Frontiers in genetics 20110101

Title: Protein modification by dicarbonyl molecular species in neurodegenerative diseases.

Journal: Journal of amino acids 20110101

Title: Optimal management of peripheral arterial disease for the non-specialist.

Journal: The Ulster medical journal 20110101

Title: Experience in the management of the severe form of human influenza A H1N1 pneumonia in an intensive care unit.

Journal: Cirugia y cirujanos 20110101

Title: No consensus on definition criteria for stroke registry common data elements.

Journal: Cerebrovascular diseases extra 20110101

Title: Statin Hepatotoxicity: Is it a Real Concern?

Journal: Heart views : the official journal of the Gulf Heart Association 20110101

Title: Statins: past and present.

Journal: Heart views : the official journal of the Gulf Heart Association 20110101

Title: In vivo bioavailability studies of sumatriptan succinate buccal tablets.

Journal: Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences 20110101

Title: High-efficiency loading and controlled release of highly water-soluble drug, pravastatin sodium by use of cross-linked β-cyclodextrin.

Journal: International journal of pharmaceutical investigation 20110101

Title: Garlic extract induces intestinal P-glycoprotein, but exhibits no effect on intestinal and hepatic CYP3A4 in humans.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20101223

Title: Liposomal pravastatin inhibits tumor growth by targeting cancer-related inflammation.

Journal: Journal of controlled release : official journal of the Controlled Release Society 20101220

Title: A mouse macrophage lipidome.

Journal: The Journal of biological chemistry 20101217

Title: Preventive effects of pravastatin on thrombin-triggered vascular responses via Akt/eNOS and RhoA/Rac1 pathways in vivo.

Journal: Cardiovascular research 20101201

Title: Lifibrol as a model compound for a novel lipid-lowering mechanism of action.

Journal: Journal of cardiovascular pharmacology and therapeutics 20101201

Title: Lipophilic statins prevent matrix metalloproteinase-mediated cartilage collagen breakdown by inhibiting protein geranylgeranylation.

Journal: Annals of the rheumatic diseases 20101201

Title: Hypercholesterolemia in rats impairs the cholinergic system and leads to memory deficits.

Journal: Molecular and cellular neurosciences 20101201

Title: The addition of pravastatin to chemotherapy in advanced gastric carcinoma: a randomised phase II trial.

Journal: European journal of cancer (Oxford, England : 1990) 20101201

Title: In vitro evaluation of inhibitory effects of antidiabetic and antihyperlipidemic drugs on human carboxylesterase activities.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20101201

Title: Successful treatment of lipoprotein glomerulopathy in a daughter and a mother using niceritrol.

Journal: Clinical and experimental nephrology 20101201

Title: Premature senescence of vascular cells is induced by HIV protease inhibitors: implication of prelamin A and reversion by statin.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20101201

Title: IL-2 costimulation enables statin-mediated activation of human NK cells, preferentially through a mechanism involving CD56+ dendritic cells.

Journal: Cancer research 20101201

Title: Application of physiologically based pharmacokinetic modeling and clearance concept to drugs showing transporter-mediated distribution and clearance in humans.

Journal: Journal of pharmacokinetics and pharmacodynamics 20101201

Title: Atorvastatin-induced acute elevation of hepatic enzymes and the absence of cross-toxicity of pravastatin.

Journal: International journal of clinical pharmacology and therapeutics 20101201

Title: Clearance (née Rowland) concepts: a downdate and an update.

Journal: Journal of pharmacokinetics and pharmacodynamics 20101201

Title: Cardiovascular diseases. Introduction.

Journal: Atherosclerosis. Supplements 20101201

Title: Pitavastatin - results from phase III & IV.

Journal: Atherosclerosis. Supplements 20101201

Title: Pitavastatin - from clinical trials to clinical practice.

Journal: Atherosclerosis. Supplements 20101201

Title: A retrospective study on the efficacy of a ten-milligram dosage of atorvastatin for treatment of hypercholesterolemia in type 2 diabetes mellitus patients.

Journal: Korean diabetes journal 20101201

Title: Effect of atorvastatin in patients with chronic heart failure - insights from randomized clinical trials.

Journal: Archives of medical science : AMS 20101201

Title: KIF6 p.Trp719Arg Testing to Assess Risk of Coronary Artery Disease and/or Statin Response.

Journal: PLoS currents 20101126

Title: What is the optimal blood pressure in patients after acute coronary syndromes?: Relationship of blood pressure and cardiovascular events in the PRavastatin OR atorVastatin Evaluation and Infection Therapy-Thrombolysis In Myocardial Infarction (PROVE IT-TIMI) 22 trial.

Journal: Circulation 20101123

Title: Efficacy and safety of more intensive lowering of LDL cholesterol: a meta-analysis of data from 170,000 participants in 26 randomised trials.

Journal: Lancet (London, England) 20101113

Title: Intensive lowering of LDL cholesterol with 80 mg versus 20 mg simvastatin daily in 12,064 survivors of myocardial infarction: a double-blind randomised trial.

Journal: Lancet (London, England) 20101113

Title: Simvastatin and purine analogs have a synergic effect on apoptosis of chronic lymphocytic leukemia cells.

Journal: Annals of hematology 20101101

Title: Prevalence and overlap of different lipid abnormalities in statin-treated patients at high cardiovascular risk in clinical practice in Germany.

Journal: Clinical research in cardiology : official journal of the German Cardiac Society 20101101

Title: Simvastatin induces osteogenic differentiation of murine embryonic stem cells.

Journal: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20101101

Title: Modulation of the Rho/ROCK pathway in heart and lung after thorax irradiation reveals targets to improve normal tissue toxicity.

Journal: Current drug targets 20101101

Title: Effect of pravastatin on bleomycin-induced acute lung injury and pulmonary fibrosis.

Journal: Clinical and experimental pharmacology & physiology 20101101

Title: The nitric oxide-donating pravastatin, NCX 6550, inhibits cytokine release and NF-κB activation while enhancing PPARγ expression in human monocyte/macrophages.

Journal: Pharmacological research 20101101

Title: Molecular cloning and characterization of the global regulator LaeA in Penicillium citrinum.

Journal: Biotechnology letters 20101101

Title: Induction of endothelial nitric oxide synthase, SIRT1, and catalase by statins inhibits endothelial senescence through the Akt pathway.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20101101

Title: Towards a unifying, systems biology understanding of large-scale cellular death and destruction caused by poorly liganded iron: Parkinson's, Huntington's, Alzheimer's, prions, bactericides, chemical toxicology and others as examples.

Journal: Archives of toxicology 20101101

Title: Genome-wide association study identifies two novel regions at 11p15.5-p13 and 1p31 with major impact on acute-phase serum amyloid A.

Journal: PLoS genetics 20101101

Title: Diabetes & coronary heart disease: current perspectives.

Journal: The Indian journal of medical research 20101101

Title: Pravastatin potentiates increases in serum adiponectin concentration in dyslipidemic patients receiving thiazolidinedione: the DOLPHIN study.

Journal: Journal of atherosclerosis and thrombosis 20101027

Title: Effects of pravastatin on murine chronic graft-versus-host disease.

Journal: Transplantation 20101027

Title: Liquid chromatography-tandem mass spectrometric assay for pravastatin and two isomeric metabolites in mouse plasma and tissue homogenates.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20101015

Title: LC-MS/MS method for the determination of several drugs used in combined cardiovascular therapy in human plasma.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20101015

Title: Investigation of microcystin congener-dependent uptake into primary murine neurons.

Journal: Environmental health perspectives 20101001

Title: Coadministration of dalcetrapib with pravastatin, rosuvastatin, or simvastatin: no clinically relevant drug-drug interactions.

Journal: Journal of clinical pharmacology 20101001

Title: Atherogenic dyslipidemia: cardiovascular risk and dietary intervention.

Journal: Lipids 20101001

Title: Enhancement of recombinant enzyme activity in cpxA-deficient mutant of Escherichia coli.

Journal: Journal of bioscience and bioengineering 20101001

Title: Two weeks taurine supplementation reverses endothelial dysfunction in young male type 1 diabetics.

Journal: Diabetes & vascular disease research 20101001

Title: Intestinal absorption of HMG-CoA reductase inhibitor pravastatin mediated by organic anion transporting polypeptide.

Journal: Pharmaceutical research 20101001

Title: Use of statins in patients with chronic hepatitis C.

Journal: Southern medical journal 20101001

Title: KIF6 polymorphism as a predictor of risk of coronary events and of clinical event reduction by statin therapy.

Journal: The American journal of cardiology 20101001

Title: Acceptable incremental cost effectiveness ratio for use of new drugs, cases in statin therapies.

Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20101001

Title: Atorvastatin-induced pancreatitis.

Journal: Indian journal of pharmacology 20101001

Title: [Indications for statin therapy in patients with acute coronary syndrome of ischemic origin].

Journal: Giornale italiano di cardiologia (2006) 20101001

Title: Dyslipidaemia in hypertensive obese type 2 diabetic patients in Jamaica.

Journal: Archives of medical science : AMS 20101001

Title: Efficacy and safety of adding fenofibrate 160 mg in high-risk patients with mixed hyperlipidemia not controlled by pravastatin 40 mg monotherapy.

Journal: The American journal of cardiology 20100915

Title: Progression of brain atrophy and cognitive decline in diabetes mellitus: a 3-year follow-up.

Journal: Neurology 20100914

Title: Mevastatin accelerates loss of synaptic proteins and neurite degeneration in aging cortical neurons in a heme-independent manner.

Journal: Neurobiology of aging 20100901

Title: Lipid Lowering Activity of Anthocephalus indicus Root in Hyperlipidemic Rats.

Journal: Evidence-based complementary and alternative medicine : eCAM 20100901

Title: No significant effect of uridine or pravastatin treatment for HIV lipoatrophy in men who have ceased thymidine analogue nucleoside reverse transcriptase inhibitor therapy: a randomized trial.

Journal: HIV medicine 20100901

Title: Drug-drug interactions between raltegravir and pravastatin in healthy volunteers.

Journal: Journal of acquired immune deficiency syndromes (1999) 20100901

Title: Do statins beneficially or adversely affect glucose homeostasis?

Journal: Current vascular pharmacology 20100901

Title: Lung function and risk of type 2 diabetes and fatal and nonfatal major coronary heart disease events: possible associations with inflammation.

Journal: Diabetes care 20100901

Title: Reduction of endoplasmic reticulum stress--a novel mechanism of action of statins in the protection against atherosclerosis.

Journal: Atherosclerosis 20100901

Title: Profiling induction of cytochrome p450 enzyme activity by statins using a new liquid chromatography-tandem mass spectrometry cocktail assay in human hepatocytes.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20100901

Title: Biosynthesis of lovastatin and related metabolites formed by fungal iterative PKS enzymes.

Journal: Biopolymers 20100901

Title: On the combined effect of statins and lycopene on cytokine production by human peripheral blood cells.

Journal: Heart and vessels 20100901

Title: Effectiveness, safety and cost of drug substitution in hypertension.

Journal: British journal of clinical pharmacology 20100901

Title: Results of a safety initiative for patients on concomitant amiodarone and simvastatin therapy in a Veterans Affairs medical center.

Journal: Journal of managed care pharmacy : JMCP 20100901

Title: Effects of drug interactions on biotransformation and antiplatelet effect of clopidogrel in vitro.

Journal: British journal of pharmacology 20100901

Title: Office-based global cardiometabolic risk assessment: a simple tool incorporating nontraditional markers.

Journal: Critical pathways in cardiology 20100901

Title: Disparate effects of atorvastatin compared with simvastatin on C-reactive protein concentrations in patients with type 2 diabetes.

Journal: Diabetes care 20100901

Title: Persistence with statins and onset of rheumatoid arthritis: a population-based cohort study.

Journal: PLoS medicine 20100901

Title: Literature mining for the discovery of hidden connections between drugs, genes and diseases.

Journal: PLoS computational biology 20100901

Title: Drug off-target effects predicted using structural analysis in the context of a metabolic network model.

Journal: PLoS computational biology 20100901

Title: Ultrasound diagnosis of bilateral quadriceps tendon rupture after statin use.

Journal: The western journal of emergency medicine 20100901

Title: [OATP 1B1 T521C/A388G is an important polymorphism gene related to neonatal hyperbilirubinemia].

Journal: Zhonghua er ke za zhi = Chinese journal of pediatrics 20100901

Title: Association between lowering low-density lipoprotein cholesterol with pravastatin and primary prevention of cardiovascular disease in mild to moderate hypercholesterolemic Japanese.

Journal: Journal of atherosclerosis and thrombosis 20100831

Title: Pravastatin attenuates cardiac dysfunction induced by lysophosphatidylcholine in isolated rat hearts.

Journal: European journal of pharmacology 20100825

Title: On-statin cholesteryl ester transfer protein mass and risk of recurrent coronary events (from the pravastatin or atorvastatin evaluation and infection therapy-thrombolysis in myocardial infarction 22 [PROVE IT-TIMI 22] study).

Journal: The American journal of cardiology 20100815

Title: Can a statin neutralize the cardiovascular risk of unhealthy dietary choices?

Journal: The American journal of cardiology 20100815

Title: Pharmacokinetic modeling of the hepatobiliary transport mediated by cooperation of uptake and efflux transporters.

Journal: Drug metabolism reviews 20100801

Title: KIF6 Trp719Arg polymorphism and the effect of statin therapy in elderly patients: results from the PROSPER study.

Journal: European journal of cardiovascular prevention and rehabilitation : official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology 20100801

Title: Telomeres are shorter in myocardial infarction patients compared to healthy subjects: correlation with environmental risk factors.

Journal: Journal of molecular medicine (Berlin, Germany) 20100801

Title: Effect of combining ACE inhibitor and statin in lupus-prone mice.

Journal: Clinical immunology (Orlando, Fla.) 20100801

Title: Scavenger receptor-B1 and luteal function in mice.

Journal: Journal of lipid research 20100801

Title: Effect of pravastatin on ventricular arrhythmias in infarcted rats: role of connexin43.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20100801

Title: Unusual pattern of dyslipidemia in children receiving steroid minimization immunosuppression after renal transplantation.

Journal: Clinical journal of the American Society of Nephrology : CJASN 20100801

Title: Anatomy and physiology of coronary blood flow.

Journal: Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology 20100801

Title: Deficiency of rac1 blocks NADPH oxidase activation, inhibits endoplasmic reticulum stress, and reduces myocardial remodeling in a mouse model of type 1 diabetes.

Journal: Diabetes 20100801

Title: Comparative study of bezafibrate and pravastatin in patients with coronary artery disease and high levels of remnant lipoprotein.

Journal: Circulation journal : official journal of the Japanese Circulation Society 20100801

Title: Erythema multiforme photoinduced by statins.

Journal: Photodermatology, photoimmunology & photomedicine 20100801

Title: Effects of fungal statins on high-glucose-induced mouse mesangial cell hypocontractility may involve filamentous actin, t-complex polypeptide 1 subunit beta, and glucose regulated protein 78.

Journal: Translational research : the journal of laboratory and clinical medicine 20100801

Title: Activation of c-Jun N-terminal kinase is required for mevastatin-induced apoptosis of salivary adenoid cystic carcinoma cells.

Journal: Anti-cancer drugs 20100801

Title: Comparison of atorvastatin 80 mg/day versus simvastatin 20 to 40 mg/day on frequency of cardiovascular events late (five years) after acute myocardial infarction (from the Incremental Decrease in End Points through Aggressive Lipid Lowering [IDEAL] trial).

Journal: The American journal of cardiology 20100801

Title: Acute activation of eNOS by statins involves scavenger receptor-B1, G protein subunit Gi, phospholipase C and calcium influx.

Journal: British journal of pharmacology 20100801

Title: Pravastatin administration does not induce detrimental effects on hemodynamics and collaterals of portal hypertensive rats.

Journal: Journal of gastroenterology and hepatology 20100801

Title: Pitavastatin for the treatment of primary hyperlipidemia and mixed dyslipidemia.

Journal: Expert review of cardiovascular therapy 20100801

Title: The cardio-protective properties of Ncx-6550, a nitric oxide donating pravastatin, in the mouse.

Journal: Microcirculation (New York, N.Y. : 1994) 20100801

Title: Identification of attractive drug targets in neglected-disease pathogens using an in silico approach.

Journal: PLoS neglected tropical diseases 20100801

Title: Complex atheromatosis of the aortic arch in cerebral infarction.

Journal: Current cardiology reviews 20100801

Title: Flavonoids: antioxidants against atherosclerosis.

Journal: Nutrients 20100801

Title: Switching to aggressive statin improves vascular endothelial function in patients with stable coronary artery disease.

Journal: Journal of atherosclerosis and thrombosis 20100730

Title: Chronic cholesterol depletion using statin impairs the function and dynamics of human serotonin(1A) receptors.

Journal: Biochemistry 20100706

Title: Effect of HMG-CoA reductase inhibitors on vascular cell apoptosis: beneficial or detrimental?

Journal: Atherosclerosis 20100701

Title: Association between percutaneous coronary intervention and long-term C-reactive protein levels in patients with acute coronary syndromes.

Journal: Journal of thrombosis and thrombolysis 20100701

Title: Pravastatin attenuates carboplatin-induced nephrotoxicity in rodents via peroxisome proliferator-activated receptor alpha-regulated heme oxygenase-1.

Journal: Molecular pharmacology 20100701

Title: A prospective analysis of elevated fasting glucose levels and cognitive function in older people: results from PROSPER and the Rotterdam Study.

Journal: Diabetes 20100701

Title: The influence of Sam-Chil-Geun (Panax notoginseng) on the serum lipid levels and inflammations of rats with hyperlipidemia induced by poloxamer-407.

Journal: Yonsei medical journal 20100701

Title: Lipid-lowering drugs and heart failure: where do we go after the statin trials?

Journal: Current opinion in cardiology 20100701

Title: Using pravastatin to improve the vascular reactivity in a mouse model of soluble fms-like tyrosine kinase-1-induced preeclampsia.

Journal: Obstetrics and gynecology 20100701

Title: Lack of effect of statins on maintenance of normal sinus rhythm following electrical cardioversion of persistent atrial fibrillation.

Journal: International journal of clinical practice 20100701

Title: Effects of 3-hydroxy-3-methylglutaryl-coenzyme a reductase inhibitor pravastatin on membrane lipids and membrane associated functions of Methanothermobacter thermautotrophicus.

Journal: Folia microbiologica 20100701

Title: Discovery of a new human polyomavirus associated with trichodysplasia spinulosa in an immunocompromized patient.

Journal: PLoS pathogens 20100701

Title: Treatment with pravastatin and fenofibrate improves atherogenic lipid profiles but not inflammatory markers in ACTG 5087.

Journal: Journal of clinical lipidology 20100701

Title: Sterol-induced dislocation of 3-hydroxy-3-methylglutaryl coenzyme A reductase from endoplasmic reticulum membranes into the cytosol through a subcellular compartment resembling lipid droplets.

Journal: The Journal of biological chemistry 20100618

Title: A novel statin-mediated 'prenylation block-and-release' assay provides insight into the membrane targeting mechanisms of small GTPases.

Journal: Biochemical and biophysical research communications 20100618

Title: Effect of pravastatin on experimental diabetic wound healing.

Journal: The Journal of surgical research 20100615

Title: Solanapyrone synthase, a possible Diels-Alderase and iterative type I polyketide synthase encoded in a biosynthetic gene cluster from Alternaria solani.

Journal: Chembiochem : a European journal of chemical biology 20100614

Title: Residential traffic exposure, pulse pressure, and C-reactive protein: consistency and contrast among exposure characterization methods.

Journal: Environmental health perspectives 20100601

Title: Mitochondrial K(ATP) channels-derived reactive oxygen species activate pro-survival pathway in pravastatin-induced cardioprotection.

Journal: Apoptosis : an international journal on programmed cell death 20100601

Title: Activation of AMP-activated protein kinase inhibits oxidized LDL-triggered endoplasmic reticulum stress in vivo.

Journal: Diabetes 20100601

Title: Enatiomerically pure hydroxycarboxylic acids: current approaches and future perspectives.

Journal: Applied microbiology and biotechnology 20100601

Title: Development of a high-throughput method for the determination of ethosuximide in human plasma by liquid chromatography mass spectrometry.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20100601

Title: Retrospective, observation study: Quantitative and qualitative effect of ezetimibe and HMG-CoA reductase inhibitors on LDL-cholesterol: are there disappearance thresholds for small, dense LDL and IDL?

Journal: Recent patents on cardiovascular drug discovery 20100601

Title: Post-prandial lipid metabolism, lipid-modulating agents and cerebrovascular integrity: implications for dementia risk.

Journal: Atherosclerosis. Supplements 20100601

Title: Severe hypocholesterolaemia is often neglected in haematological malignancies.

Journal: European journal of cancer (Oxford, England : 1990) 20100601

Title: In vitro synergistic interactions of the effects of various statins and azoles against some clinically important fungi.

Journal: FEMS microbiology letters 20100601

Title: Aspirin and pravastatin reduce lectin-like oxidized low density lipoprotein receptor-1 expression, adhesion molecules and oxidative stress in human coronary artery endothelial cells.

Journal: Chinese medical journal 20100601

Title: Molecular mechanism of ochratoxin a transport in the kidney.

Journal: Toxins 20100601

Title: A historical perspective on the discovery of statins.

Journal: Proceedings of the Japan Academy. Series B, Physical and biological sciences 20100511

Title: Lipophilic but not hydrophilic statins selectively induce cell death in gynaecological cancers expressing high levels of HMGCoA reductase.

Journal: Journal of cellular and molecular medicine 20100501

Title: Genetic variation at the NPC1L1 gene locus, plasma lipoproteins, and heart disease risk in the elderly.

Journal: Journal of lipid research 20100501

Title: Lipoprotein-associated phospholipase A(2), inflammatory biomarkers, and risk of cardiovascular disease in the Prospective Study of Pravastatin in the Elderly at Risk (PROSPER).

Journal: Atherosclerosis 20100501

Title: Relationships between metabolic syndrome and other baseline factors and the efficacy of ezetimibe/simvastatin and atorvastatin in patients with type 2 diabetes and hypercholesterolemia.

Journal: Diabetes care 20100501

Title: Inhibition of necrotic actions of nitrogen-containing bisphosphonates (NBPs) and their elimination from bone by etidronate (a non-NBP): a proposal for possible utilization of etidronate as a substitution drug for NBPs.

Journal: Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons 20100501

Title: Lipoprotein-associated phospholipase A2 activity and incident coronary heart disease among men and women with type 2 diabetes.

Journal: Diabetes 20100501

Title: Different effects of commonly prescribed statins on abdominal aortic aneurysm wall biology.

Journal: European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery 20100501

Title: Coronary plaque regression and lifestyle modification in patients treated with pravastatin. - Assessment mainly by daily aerobic exercise and an increase in the serum level of high-density lipoprotein cholesterol -.

Journal: Circulation journal : official journal of the Japanese Circulation Society 20100501

Title: Effect of pravastatin therapy on coronary events in carriers of the KIF6 719Arg allele from the cholesterol and recurrent events trial.

Journal: The American journal of cardiology 20100501

Title: Correlates of the severity of coronary atherosclerosis in long-term kidney transplant patients.

Journal: Journal of Korean medical science 20100501

Title: Involvement of an influx transporter in the blood-brain barrier transport of naloxone.

Journal: Biopharmaceutics & drug disposition 20100501

Title: Approach to the patient who is intolerant of statin therapy.

Journal: The Journal of clinical endocrinology and metabolism 20100501

Title: [Pravastatin inhibits the expression of syndecan-4 protein in tumor necrosis factor-alpha-induced rat vascular smooth muscle cells in vitro].

Journal: Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20100501

Title: [Mevastatin inhibits the differentiation of thyroid-associated ophthalmopathy derived orbital preadipocytes].

Journal: Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20100501

Title: [Effects of pravastatin on the expression of transforming growth factor-beta 1 in cardiac fibroblasts].

Journal: Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 20100501

Title: The Role of Asymmetric Dimethylarginine (ADMA) in Endothelial Dysfunction and Cardiovascular Disease.

Journal: Current cardiology reviews 20100501

Title: Lipid metabolism and HCV infection.

Journal: Viruses 20100501

Title: Long-term efficacy of pravastatin therapy in diabetic patients undergoing complete coronary revascularization.

Journal: Journal of atherosclerosis and thrombosis 20100430

Title: Can intensive lipid-lowering therapy with statins ameliorate atherosclerosis in Japanese patients? Rationale and design of the JART study.

Journal: Journal of atherosclerosis and thrombosis 20100430

Title: Differential effects of statins (pravastatin or simvastatin) on ventricular ectopic complexes: Galpha(i2), a possible molecular marker for ventricular irritability.

Journal: The American journal of cardiology 20100415

Title: Rapid multilabel detection of geranylgeranylated proteins by using bioorthogonal ligation chemistry.

Journal: Chembiochem : a European journal of chemical biology 20100412

Title: Statins improve visual field alterations related to hypercholesterolemia.

Journal: Atherosclerosis 20100401

Title: Effects of mevastatin on grafted bone in MRL/MpJ mice.

Journal: Connective tissue research 20100401

Title: Tolerability of pravastatin in pediatric hematopoietic stem cell transplant patients with bronchiolitis obliterans.

Journal: Journal of pediatric hematology/oncology 20100401

Title: Assessment of a safety enhancement to the hospital medication reconciliation process for elderly patients.

Journal: The American journal of geriatric pharmacotherapy 20100401

Title: A systematic review and meta-analysis on the therapeutic equivalence of statins.

Journal: Journal of clinical pharmacy and therapeutics 20100401

Title: [Effects of pravastatin on the proliferation and invasion of human hepatocarcinoma HepG2 cell line].

Journal: Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20100401

Title: Ochratoxin a: general overview and actual molecular status.

Journal: Toxins 20100401

Title: Effect of olmesartan and pravastatin on experimental cerebral aneurysms in rats.

Journal: Brain research 20100331

Title: In vitro antioxidant activity of pravastatin provides vascular protection.

Journal: European journal of pharmacology 20100325

Title: Statins in acute coronary syndromes and genetic insight.

Journal: Journal of the American College of Cardiology 20100323

Title: Letter by Superko and King regarding article, 'Lipid Treatment Assessment Project 2: a multinational survey to evaluate the proportion of patients achieving low-density lipoprotein cholesterol goals'.

Journal: Circulation 20100309

Title: Angiotensin II receptor blocker and statins lower elevated levels of osteopontin in essential hypertension--results from the EUTOPIA trial.

Journal: Atherosclerosis 20100301

Title: Impact of inactivity and exercise on the vasculature in humans.

Journal: European journal of applied physiology 20100301

Title: Association of the TNF-{alpha}-C-857T polymorphism with resistance to the cholesterol-lowering effect of HMG-CoA reductase inhibitors in type 2 diabetic subjects.

Journal: Diabetes care 20100301

Title: Activation of hemostasis and decline in cognitive function in older people.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20100301

Title: Expression, localization, and pharmacological role of Kv7 potassium channels in skeletal muscle proliferation, differentiation, and survival after myotoxic insults.

Journal: The Journal of pharmacology and experimental therapeutics 20100301

Title: BMPER is upregulated by statins and modulates endothelial inflammation by intercellular adhesion molecule-1.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20100301

Title: Effect of statins on the viability of macrophages and smooth muscle cells.

Journal: Journal of cardiovascular pharmacology 20100301

Title: Statins for the treatment of obstetric complications in antiphospholipid syndrome?

Journal: Journal of reproductive immunology 20100301

Title: Drug interactions with HMG-CoA reductase inhibitors (statins): the importance of CYP enzymes, transporters and pharmacogenetics.

Journal: Current opinion in investigational drugs (London, England : 2000) 20100301

Title: Pitavastatin: a new HMG-CoA reductase inhibitor.

Journal: The Annals of pharmacotherapy 20100301

Title: Distribution of traditional and novel risk factors and their relation to subsequent cardiovascular events in patients with acute coronary syndromes (from the PROVE IT-TIMI 22 trial).

Journal: The American journal of cardiology 20100301

Title: Comparative study of low doses of rosuvastatin and atorvastatin on lipid and glycemic control in patients with metabolic syndrome and hypercholesterolemia.

Journal: The Korean journal of internal medicine 20100301

Title: Buccal drug delivery of pravastatin sodium.

Journal: AAPS PharmSciTech 20100301

Title: Pravastatin treatment before coronary artery bypass grafting for reduction of postoperative atrial fibrillation.

Journal: General thoracic and cardiovascular surgery 20100301

Title: Role of C-reactive protein in contributing to increased cardiovascular risk in metabolic syndrome.

Journal: Current atherosclerosis reports 20100301

Title: Past, present and future therapeutics for cerebellar ataxias.

Journal: Current neuropharmacology 20100301

Title: Pravastatin treatment causes a shift in the balance of hippocampal neurotransmitter binding densities towards inhibition.

Journal: Brain research 20100226

Title: Myelin basic protein priming reduces the expression of Foxp3 in T cells via nitric oxide.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20100215

Title: Cholesterol reduction impairs exocytosis of synaptic vesicles.

Journal: Journal of cell science 20100215

Title: HMG-CoA reductase inhibitors (statins) activate expression of PPARalpha/PPARgamma and ABCA1 in cultured gallbladder epithelial cells.

Journal: Digestive diseases and sciences 20100201

Title: Is cyclosporine A transport inhibited by pravastatin via multidrug resistant protein 2?

Journal: European journal of clinical pharmacology 20100201

Title: Pravastatin use and cancer risk: a meta-analysis of individual patient data from long-term prospective controlled trials in Japan.

Journal: Pharmacoepidemiology and drug safety 20100201

Title: Investigation of the rate-determining process in the hepatic elimination of HMG-CoA reductase inhibitors in rats and humans.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20100201

Title: In vitro interactions between primycin and different statins in their effects against some clinically important fungi.

Journal: Journal of medical microbiology 20100201

Title: Effects of walnut consumption on endothelial function in type 2 diabetic subjects: a randomized controlled crossover trial.

Journal: Diabetes care 20100201

Title: The influence of SLCO1B1 (OATP1B1) gene polymorphisms on response to statin therapy.

Journal: The pharmacogenomics journal 20100201

Title: Endothelial function in subjects with isolated low HDL cholesterol: role of nitric oxide and circulating progenitor cells.

Journal: American journal of physiology. Endocrinology and metabolism 20100201

Title: HMGCR gene polymorphism is associated with stroke risk in the EPIC-Norfolk study.

Journal: European journal of cardiovascular prevention and rehabilitation : official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology 20100201

Title: [A negative first-line work-up of Raynaud's phenomenon: And what if it were cancer?].

Journal: Journal des maladies vasculaires 20100201

Title: Pravastatin counteracts angiotensin II-induced upregulation and activation of NADPH oxidase at plasma membrane of human endothelial cells.

Journal: Journal of cardiovascular pharmacology 20100201

Title: Effect of pravastatin on kidney function and urinary protein excretion in autosomal dominant polycystic kidney disease.

Journal: Scandinavian journal of urology and nephrology 20100201

Title: Beneficial microvascular and anti-inflammatory effects of pravastatin during sepsis involve nitric oxide synthase III.

Journal: British journal of anaesthesia 20100201

Title: Safety and tolerability of dalcetrapib (RO4607381/JTT-705): results from a 48-week trial.

Journal: European heart journal 20100201

Title: Relevance of conserved lysine and arginine residues in transmembrane helices for the transport activity of organic anion transporting polypeptide 1B3.

Journal: British journal of pharmacology 20100201

Title: Commentary on pravastatin and cancer: need for individual patient data meta-analyses.

Journal: Pharmacoepidemiology and drug safety 20100201

Title: Fibrate/Statin initiation in warfarin users and gastrointestinal bleeding risk.

Journal: The American journal of medicine 20100201

Title: Vitamin E prevents steroid-induced osteonecrosis in rabbits.

Journal: Acta orthopaedica 20100201

Title: [Heparin-induced thrombocytopenia and disseminated intravascular coagulation in a patient with drug-induced pneumonia].

Journal: Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society 20100201

Title: Nicotinic acid + larodiorant. Laropiprant adds its own adverse effects.

Journal: Prescrire international 20100201

Title: Effect of preoperative statin therapy on myocardial protection and morbidity endpoints following off-pump coronary bypass surgery in patients with elevated C-reactive protein level.

Journal: Korean journal of anesthesiology 20100201

Title: Farnesyl pyrophosphate inhibits epithelialization and wound healing through the glucocorticoid receptor.

Journal: The Journal of biological chemistry 20100115

Title: Relation of change in apolipoprotein B/apolipoprotein A-I ratio to coronary plaque regression after Pravastatin treatment in patients with coronary artery disease.

Journal: The American journal of cardiology 20100115

Title: Tolerability of red yeast rice (2,400 mg twice daily) versus pravastatin (20 mg twice daily) in patients with previous statin intolerance.

Journal: The American journal of cardiology 20100115

Title: Rosuvastatin versus pravastatin in dyslipidemic HIV-1-infected patients receiving protease inhibitors: a randomized trial.

Journal: AIDS (London, England) 20100102

Title: Effects of pravastatin on serum osteoprotegerin levels in patients with hypercholesterolemia and type 2 diabetes.

Journal: Angiology 20100101

Title: Survival analysis using inverse probability of treatment weighted methods based on the generalized propensity score.

Journal: Pharmaceutical statistics 20100101

Title: Cholesterol absorption and synthesis markers in individuals with and without a CHD event during pravastatin therapy: insights from the PROSPER trial.

Journal: Journal of lipid research 20100101

Title: Pravastatin and cognitive function in the elderly. Results of the PROSPER study.

Journal: Journal of neurology 20100101

Title: Down-regulation of RhoA is involved in the cytotoxic action of lipophilic statins in HepG2 cells.

Journal: Atherosclerosis 20100101

Title: HPLC and mass spectrometry analysis of dolichol-phosphates at the cell culture scale.

Journal: Analytical biochemistry 20100101

Title: Biotechnological production and applications of statins.

Journal: Applied microbiology and biotechnology 20100101

Title: Cholesteryl ester transfer protein: at the heart of the action of lipid-modulating therapy with statins, fibrates, niacin, and cholesteryl ester transfer protein inhibitors.

Journal: European heart journal 20100101

Title: Functional characterization of mouse organic anion transporting peptide 1a4 in the uptake and efflux of drugs across the blood-brain barrier.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20100101

Title: A role of nitric oxide in neurite outgrowth of neuroblastoma cells triggered by mevastatin or serum reduction.

Journal: Neuroscience letters 20100101

Title: HIV-associated dyslipidaemia among HIV antibody-positive patients in Ireland: prevalence and management strategies.

Journal: International journal of STD & AIDS 20100101

Title: 11C-meta-hydroxyephedrine defects persist despite functional improvement in hibernating myocardium.

Journal: Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology 20100101

Title: Synergistic antifibrotic efficacy of statin and protein kinase C inhibitor in hepatic fibrosis.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20100101

Title: Differing effect of statins on insulin sensitivity in non-diabetics: a systematic review and meta-analysis.

Journal: Diabetes research and clinical practice 20100101

Title: Effect of long- and short-term treatments with pravastatin on diabetes mellitus and pancreatic fibrosis in the Otsuka-Long-Evans-Tokushima fatty rat.

Journal: British journal of pharmacology 20100101

Title: Simvastatin does not affect vitamin d status, but low vitamin d levels are associated with dyslipidemia: results from a randomised, controlled trial.

Journal: International journal of endocrinology 20100101

Title: Does higher usage of low-cost statins correlate with a poorer achievement in cholesterol quality markers for secondary prevention?

Journal: The British journal of general practice : the journal of the Royal College of General Practitioners 20100101

Title: Standards of medical care in diabetes--2010.

Journal: Diabetes care 20100101

Title: The disposition of pravastatin in a rat model of streptozotocin-induced diabetes and organic anion transporting polypeptide 2 and multidrug resistance-associated protein 2 expression in the liver.

Journal: Biological & pharmaceutical bulletin 20100101

Title: Evaluating clinical periodontal measures as surrogates for bacterial exposure: the Oral Infections and Vascular Disease Epidemiology Study (INVEST).

Journal: BMC medical research methodology 20100101

Title: A novel method to adjust efficacy estimates for uptake of other active treatments in long-term clinical trials.

Journal: PloS one 20100101

Title: Cloning, reassembling and integration of the entire nikkomycin biosynthetic gene cluster into Streptomyces ansochromogenes lead to an improved nikkomycin production.

Journal: Microbial cell factories 20100101

Title: Metabolism of a lipid nanoemulsion resembling low-density lipoprotein in patients with grade iii obesity.

Journal: Clinics (Sao Paulo, Brazil) 20100101

Title: Sex and ethnic differences in 47 candidate proteomic markers of cardiovascular disease: the Mayo Clinic proteomic markers of arteriosclerosis study.

Journal: PloS one 20100101

Title: MutS and MutL are dispensable for maintenance of the genomic mutation rate in the halophilic archaeon Halobacterium salinarum NRC-1.

Journal: PloS one 20100101

Title: Efficacy and safety of ezetimibe for Japanese patients with dyslipidaemia: The ESSENTIAL Study.

Journal: Clinical drug investigation 20100101

Title: General practitioners' perceptions of the effectiveness of medical interventions: an exploration of underlying constructs.

Journal: Implementation science : IS 20100101

Title: Anti-hyperglycemic and anti-hyperlipidemic effects of guava leaf extract.

Journal: Nutrition & metabolism 20100101

Title: CCR2 and coronary artery disease: a woscops substudy.

Journal: BMC research notes 20100101

Title: Can statins prevent or help treat Alzheimer's disease?

Journal: Journal of Alzheimer's disease : JAD 20100101

Title: Effect of glitazones on the progression of coronary artery disease in type 2 diabetes patients.

Journal: Vascular health and risk management 20100101

Title: Cholesteryl ester transfer protein gene polymorphisms and longevity syndrome.

Journal: The open cardiovascular medicine journal 20100101

Title: TRAF1/C5 polymorphism is not associated with increased mortality in rheumatoid arthritis: two large longitudinal studies.

Journal: Arthritis research & therapy 20100101

Title: Variations in atherosclerosis and remodeling patterns in aorta and carotids.

Journal: Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance 20100101

Title: An alternative treatment of hyperlipidemia with red yeast rice: a case report.

Journal: Journal of medical case reports 20100101

Title: Association of repeatedly measured intermediate risk factors for complex diseases with high dimensional SNP data.

Journal: Algorithms for molecular biology : AMB 20100101

Title: Preadmission statin use and one-year mortality among patients in intensive care - a cohort study.

Journal: Critical care (London, England) 20100101

Title: Evaluation of different formulas for LDL-C calculation.

Journal: Lipids in health and disease 20100101

Title: Pre-hospital ECG for acute coronary syndrome in urban India: a cost-effectiveness analysis.

Journal: BMC cardiovascular disorders 20100101

Title: Current status and future directions in lipid management: emphasizing low-density lipoproteins, high-density lipoproteins, and triglycerides as targets for therapy.

Journal: Vascular health and risk management 20100101

Title: Lovastatin induces apoptosis of ovarian cancer cells and synergizes with doxorubicin: potential therapeutic relevance.

Journal: BMC cancer 20100101

Title: The role of interleukin-18 in the metabolic syndrome.

Journal: Cardiovascular diabetology 20100101

Title: Statins, antihypertensive treatment, and blood pressure control in clinic and over 24 hours: evidence from PHYLLIS randomised double blind trial.

Journal: BMJ (Clinical research ed.) 20100101

Title: Novel approaches to treat experimental pulmonary arterial hypertension: a review.

Journal: Journal of biomedicine & biotechnology 20100101

Title: Genome-wide association of lipid-lowering response to statins in combined study populations.

Journal: PloS one 20100101

Title: Associations between total cerebral blood flow and age related changes of the brain.

Journal: PloS one 20100101

Title: Semi-parametric risk prediction models for recurrent cardiovascular events in the LIPID study.

Journal: BMC medical research methodology 20100101

Title: HMG-CoA reductase inhibitors in kidney transplant recipients receiving tacrolimus: statins not associated with improved patient or graft survival.

Journal: BMC nephrology 20100101

Title: Statins Decrease Oxidative Stress and ICD Therapies.

Journal: Cardiology research and practice 20100101

Title: Atorvastatin in stroke: a review of SPARCL and subgroup analysis.

Journal: Vascular health and risk management 20100101

Title: A systematic review of clinical trials of pharmacological interventions for acute ischaemic stroke (1955-2008) that were completed, but not published in full.

Journal: Trials 20100101

Title: Statins and cognitive functioning in the elderly: a population-based study.

Journal: Journal of Alzheimer's disease : JAD 20100101

Title: A comprehensive molecular interaction map for rheumatoid arthritis.

Journal: PloS one 20100101

Title: Prevalence and risk factors of microalbuminuria in Thai nondiabetic hypertensive patients.

Journal: Vascular health and risk management 20100101

Title: Cardiovascular dementia - a different perspective.

Journal: The open biochemistry journal 20100101

Title: Age-Related Hypercholesterolemia and HMG-CoA Reductase Dysregulation: Sex Does Matter (A Gender Perspective).

Journal: Current gerontology and geriatrics research 20100101

Title: [Drug interaction caused by communication problems. Rhabdomyolysis due to a combination of itraconazole and simvastatin].

Journal: Nederlands tijdschrift voor geneeskunde 20100101

Title: Large scale physiological readjustment during growth enables rapid, comprehensive and inexpensive systems analysis.

Journal: BMC systems biology 20100101

Title: Treatment with apolipoprotein A-1 mimetic peptide reduces lupus-like manifestations in a murine lupus model of accelerated atherosclerosis.

Journal: Arthritis research & therapy 20100101

Title: A role for the mevalonate pathway in the induction of subtype cross-reactive immunity to influenza A virus by human gammadelta T lymphocytes.

Journal: Cellular immunology 20100101

Title: Unintended effects of statins in men and women in England and Wales: population based cohort study using the QResearch database.

Journal: BMJ (Clinical research ed.) 20100101

Title: Pitavastatin: the newest HMG-CoA reductase inhibitor.

Journal: Reviews in cardiovascular medicine 20100101

Title: Statin treatment and mortality in bacterial infections--a systematic review and meta-analysis.

Journal: PloS one 20100101

Title: How to translate therapeutic recommendations in clinical practice guidelines into rules for critiquing physician prescriptions? Methods and application to five guidelines.

Journal: BMC medical informatics and decision making 20100101

Title: Cyclic nucleotides and mitogen-activated protein kinases: regulation of simvastatin in platelet activation.

Journal: Journal of biomedical science 20100101

Title: Statins in candidemia: clinical outcomes from a matched cohort study.

Journal: BMC infectious diseases 20100101

Title: Lipid profile in consecutive pregnancies.

Journal: Lipids in health and disease 20100101

Title: Synergistic effect of simvastatin and ezetimibe on lipid and pro-inflammatory profiles in pre-diabetic subjects.

Journal: Diabetology & metabolic syndrome 20100101

Title: Methylthioadenosine (MTA) inhibits melanoma cell proliferation and in vivo tumor growth.

Journal: BMC cancer 20100101

Title: Fenofibric acid: a new fibrate approved for use in combination with statin for the treatment of mixed dyslipidemia.

Journal: Vascular health and risk management 20100101

Title: Lovastatin protects against experimental plague in mice.

Journal: PloS one 20100101

Title: Pdro, a protein associated with late endosomes and lysosomes and implicated in cellular cholesterol homeostasis.

Journal: PloS one 20100101

Title: Membrane plasmalogen composition and cellular cholesterol regulation: a structure activity study.

Journal: Lipids in health and disease 20100101

Title: Interleukin-17 regulation: an attractive therapeutic approach for asthma.

Journal: Respiratory research 20100101

Title: The CaaX specificities of Arabidopsis protein prenyltransferases explain era1 and ggb phenotypes.

Journal: BMC plant biology 20100101

Title: Use of evidence-based pharmacotherapy after myocardial infarction in Estonia.

Journal: BMC public health 20100101

Title: Pulmonary Embolism Mimicking Pneumonia in a HIV Patient.

Journal: Case reports in medicine 20100101

Title: Gene activation regresses atherosclerosis, promotes health, and enhances longevity.

Journal: Lipids in health and disease 20100101

Title: The HMG-CoA reductase inhibitor pravastatin stimulates insulin secretion through organic anion transporter polypeptides.

Journal: Drug metabolism and pharmacokinetics 20100101

Title: Use of statin therapy to reduce cardiovascular risk in older patients.

Journal: Current gerontology and geriatrics research 20100101

Title: Endothelial dysfunction, inflammation, and apoptosis in diabetes mellitus.

Journal: Mediators of inflammation 20100101

Title: Ezetimibe/simvastatin vs simvastatin in coronary heart disease patients with or without diabetes.

Journal: Lipids in health and disease 20100101

Title: Genomic characterization of large rearrangements of the LDLR gene in Czech patients with familial hypercholesterolemia.

Journal: BMC medical genetics 20100101

Title: Impact of medical therapy on atheroma volume measured by different cardiovascular imaging modalities.

Journal: Cardiology research and practice 20100101

Title: Unexplained Graft Dysfunction after Heart Transplantation-Role of Novel Molecular Expression Test Score and QTc-Interval: A Case Report.

Journal: Cardiology research and practice 20100101

Title: Leukocyte Count versus C-Reactive Protein Levels in Obese Portuguese Patients Aged 6-12 Years Old.

Journal: The open biochemistry journal 20100101

Title: Clinical implications of the cytokine hypothesis of depression: the association between use of statins and aspirin and the risk of major depression.

Journal: Psychotherapy and psychosomatics 20100101

Title: Pitavastatin: a new HMG-CoA reductase inhibitor for the treatment of hypercholesterolemia.

Journal: Cardiology in review 20100101

Title: The Role of Peroxisome Proliferator-Activated Receptor beta/delta on the Inflammatory Basis of Metabolic Disease.

Journal: PPAR research 20100101

Title: Atorvastatin pretreatment diminishes the levels of myocardial ischemia markers early after CABG operation: an observational study.

Journal: Journal of cardiothoracic surgery 20100101

Title: S-layer glycoproteins and flagellins: reporters of archaeal posttranslational modifications.

Journal: Archaea (Vancouver, B.C.) 20100101

Title: Comparison of four phaC genes from Haloferax mediterranei and their function in different PHBV copolymer biosyntheses in Haloarcula hispanica.

Journal: Saline systems 20100101

Title: Management of dyslipidemias with fibrates, alone and in combination with statins: role of delayed-release fenofibric acid.

Journal: Vascular health and risk management 20100101

Title: Statins: cost analysis in Indian scenario from eight major clinical trials.

Journal: Journal of postgraduate medicine 20100101

Title: Right man, right time, right place?--on the time course of the mediator orchestra in septic shock.

Journal: Critical care (London, England) 20100101

Title: Effects of pravastatin on cellular ultrastructure and hemorheology in rats after traumatic head injury.

Journal: Clinical hemorheology and microcirculation 20100101

Title: Sizing up stability: combination therapy with Apo-AI peptide mimetics and statins in systemic lupus erythematosus-mediated atherosclerosis.

Journal: Arthritis research & therapy 20100101

Title: Atherogenic dyslipidemia and diabetes mellitus: what's new in the management arena?

Journal: Vascular health and risk management 20100101

Title: Role of olmesartan in combination therapy in blood pressure control and vascular function.

Journal: Vascular health and risk management 20100101

Title: Treatment of cardiovascular risk factors to prevent cognitive decline and dementia: a systematic review.

Journal: Vascular health and risk management 20100101

Title: Cholesterol pathways affected by small molecules that decrease sterol levels in Niemann-Pick type C mutant cells.

Journal: PloS one 20100101

Title: Small artery elasticity is decreased in patients with systemic lupus erythematosus without increased intima media thickness.

Journal: Arthritis research & therapy 20100101

Title: Statins and clinical outcome of acute ischemic stroke: a systematic review.

Journal: International archives of medicine 20100101

Title: Renal protection in diabetes: lessons from ONTARGET.

Journal: Cardiovascular diabetology 20100101

Title: Rheumatoid arthritis patients receive less frequent acute reperfusion and secondary prevention therapy after myocardial infarction compared with the general population.

Journal: Arthritis research & therapy 20100101

Title: Benefits of statin therapy and compliance in high risk cardiovascular patients.

Journal: Vascular health and risk management 20100101

Title: The relationships of markers of cholesterol homeostasis with carotid intima-media thickness.

Journal: PloS one 20100101

Title: Drug interaction and pharmacist.

Journal: Journal of young pharmacists : JYP 20100101

Title: A new mouse model to explore therapies for preeclampsia.

Journal: PloS one 20100101

Title: Ezetimibe/simvastatin 10/20 mg versus rosuvastatin 10 mg in high-risk hypercholesterolemic patients stratified by prior statin treatment potency.

Journal: Lipids in health and disease 20100101

Title: Risk assessment and aspirin use in Asian and Western populations.

Journal: Vascular health and risk management 20100101

Title: Population based screening for chronic kidney disease: cost effectiveness study.

Journal: BMJ (Clinical research ed.) 20100101

Title: Pravastatin provides antioxidant activity and protection of erythrocytes loaded Primaquine.

Journal: International journal of medical sciences 20100101

Title: Prevention of Alzheimer's disease in high risk groups: statin therapy in subjects with PSEN1 mutations or heterozygosity for apolipoprotein E epsilon 4.

Journal: Alzheimer's research & therapy 20100101

Title: Rosuvastatin promotes osteoblast differentiation and regulates SLCO1A1 transporter gene expression in MC3T3-E1 cells.

Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20100101

Title: Post-load hyperglycemia as an important predictor of long-term adverse cardiac events after acute myocardial infarction: a scientific study.

Journal: Cardiovascular diabetology 20100101

Title: Flavopiridol pharmacogenetics: clinical and functional evidence for the role of SLCO1B1/OATP1B1 in flavopiridol disposition.

Journal: PloS one 20100101

Title: Niacin or ezetimibe for patients with, or at risk of coronary heart disease.

Journal: Clinical Medicine Insights. Cardiology 20100101

Title: Indirect comparisons: a review of reporting and methodological quality.

Journal: PloS one 20100101

Title: Hypercholesterolemia and microvascular dysfunction: interventional strategies.

Journal: Journal of inflammation (London, England) 20100101

Title: The cost effectiveness of statin therapies in Spain in 2010, after the introduction of generics and reference prices.

Journal: American journal of cardiovascular drugs : drugs, devices, and other interventions 20100101

Title: Expression of 3-hydroxy-3-methylglutaryl-CoA reductase, p-hydroxybenzoate-m-geranyltransferase and genes of phenylpropanoid pathway exhibits positive correlation with shikonins content in arnebia [Arnebia euchroma (Royle) Johnston].

Journal: BMC molecular biology 20100101

Title: Lipid control and use of lipid-regulating drugs for prevention of cardiovascular events in Chinese type 2 diabetic patients: a prospective cohort study.

Journal: Cardiovascular diabetology 20100101

Title: Clinical evaluation of Dyslipidemia among type II diabetic patients at Public hospital Penang, Malaysia.

Journal: International archives of medicine 20100101

Title: Synergic effect of eicosapentaenoic acid and lovastatin on gene expression of HMGCoA reductase and LDL receptor in cultured HepG2 cells.

Journal: Lipids in health and disease 20100101

Title: Are post-treatment low-density lipoprotein subclass pattern analyses potentially misleading?

Journal: Lipids in health and disease 20100101

Title: Combination therapy of statin and ezetimibe for the treatment of familial hypercholesterolemia.

Journal: Vascular health and risk management 20100101

Title: Computerized history-taking as a tool to manage dyslipidemia.

Journal: Vascular health and risk management 20100101

Title: Low high-density lipoprotein cholesterol: current status and future strategies for management.

Journal: Vascular health and risk management 20100101

Title: Pitavastatin approved for treatment of primary hypercholesterolemia and combined dyslipidemia.

Journal: Vascular health and risk management 20100101

Title: Anti-inflammatory effects of resveratrol, curcumin and simvastatin in acute small intestinal inflammation.

Journal: PloS one 20100101

Title: Rosuvastatin reduces neointima formation in a rat model of balloon injury.

Journal: European journal of medical research 20100101

Title: Simvastatin impairs murine melanoma growth.

Journal: Lipids in health and disease 20100101

Title: Treatment of dyslipidemia in patients with type 2 diabetes.

Journal: Lipids in health and disease 20100101

Title: Data linkage: a powerful research tool with potential problems.

Journal: BMC health services research 20100101

Title: Lack of plasma albumin impairs intravascular lipolysis and explains the associated free fatty acids deficiency and hypertriglyceridemia.

Journal: Lipids in health and disease 20100101

Title: High density lipoproteins-based therapies for cardiovascular disease.

Journal: Journal of cardiovascular disease research 20100101

Title: Hyperhomocysteinemia is Associated with Aortic Atheroma Progression in Stroke/TIA Patients.

Journal: Frontiers in neurology 20100101

Title: Use of the Joint British Society cardiovascular risk calculator before initiating statins for primary prevention in hospital medicine: experience from a large university teaching hospital.

Journal: International journal of general medicine 20100101

Title: Combination of niacin extended-release and simvastatin results in a less atherogenic lipid profile than atorvastatin monotherapy.

Journal: Vascular health and risk management 20100101

Title: Optimal management of familial hypercholesterolemia: treatment and management strategies.

Journal: Vascular health and risk management 20100101

Title: Two siblings with familial chylomicronemia syndrome: disease course and effectiveness of early treatment.

Journal: Case reports in medicine 20100101

Title: Antiobesogenic and Antiatherosclerotic Properties of Caralluma fimbriata Extract.

Journal: Journal of nutrition and metabolism 20100101

Title: Drug-drug Interaction between Pravastatin and Gemfibrozil (Antihyperlipidemic) with Gliclazide (Antidiabetic) in Rats.

Journal: Journal of young pharmacists : JYP 20100101

Title: The role of RhoA/Rho kinase pathway in endothelial dysfunction.

Journal: Journal of cardiovascular disease research 20100101

Title: Rosuvastatin, inflammation, C-reactive protein, JUPITER, and primary prevention of cardiovascular disease--a perspective.

Journal: Drug design, development and therapy 20100101

Title: Signaling of reactive oxygen and nitrogen species in Diabetes mellitus.

Journal: Oxidative medicine and cellular longevity 20100101

Title: Blocking protein farnesylation improves nuclear shape abnormalities in keratinocytes of mice expressing the prelamin A variant in Hutchinson-Gilford progeria syndrome.

Journal: Nucleus (Austin, Tex.) 20100101

Title: Quality of diabetes care at Armed Forces Hospital, Southern Region, Kingdom of Saudi Arabia, 2006.

Journal: Journal of family & community medicine 20100101

Title: Controversial data on simvastatin in asthma: What about the rat model?

Journal: Journal of asthma and allergy 20100101

Title: Pitavastatin: evidence for its place in treatment of hypercholesterolemia.

Journal: Core evidence 20100101

Title: Down-regulation of the global regulator SATB1 by statins in COLO205 colon cancer cells.

Journal: Molecular medicine reports 20100101

Title: Lipid Metabolism and Cardiovascular Risk in HIV-1 Infection and HAART: Present and Future Problems.

Journal: Cholesterol 20100101

Title: Randomized Trial of a Pharmacist-Delivered Intervention for Improving Lipid-Lowering Medication Adherence among Patients with Coronary Heart Disease.

Journal: Cholesterol 20100101

Title: [Evidence-based grounds of the efficacy of simvastatin (zocor): 15 years later].

Journal: Terapevticheskii arkhiv 20100101

Title: Rosuvastatin counteracts vessel arterialisation and sinusoid capillarisation, reduces tumour growth, and prolongs survival in murine hepatocellular carcinoma.

Journal: Gastroenterology research and practice 20100101

Title: Cholesteryl ester transfer protein gene and effectiveness of lipid lowering of atorvastatin.

Journal: The open cardiovascular medicine journal 20100101

Title: Prevalence of modifiable cardiovascular risk factors in long-term renal transplant patients.

Journal: International journal of nephrology and renovascular disease 20100101

Title: A New Improved RP-HPLC Method for Assay of Rosuvastatin Calcium in Tablets.

Journal: Indian journal of pharmaceutical sciences 20100101

Title: Safety and efficacy of laropiprant and extended-release niacin combination in the management of mixed dyslipidemias and primary hypercholesterolemia.

Journal: Drug, healthcare and patient safety 20100101

Title: Intra-Laboratory Pre-Validation of a Human Cell Based in vitro Angiogenesis Assay for Testing Angiogenesis Modulators.

Journal: Frontiers in pharmacology 20100101

Title: Implications of genetic polymorphisms in inflammation-induced atherosclerosis.

Journal: The open cardiovascular medicine journal 20100101

Title: Atherothrombosis in South asians: implications of atherosclerotic and inflammatory markers.

Journal: The open cardiovascular medicine journal 20100101

Title: Screening of nutrient parameters for mevastatin production by Penicillium citrinum MTCC 1256 under submerged fermentation using the Plackett-Burman design.

Journal: Journal of pharmacy & bioallied sciences 20100101

Title: Endothelial function, blood pressure control, and risk modification: impact of irbesartan alone or in combination.

Journal: Integrated blood pressure control 20100101

Title: Impact of olmesartan on blood pressure, endothelial function, and cardiovascular outcomes.

Journal: Integrated blood pressure control 20100101

Title: Long-term treatment of patients with HIV-1: the role of atazanavir.

Journal: HIV/AIDS (Auckland, N.Z.) 20100101

Title: New and emerging agents in the management of lipodystrophy in HIV-infected patients.

Journal: HIV/AIDS (Auckland, N.Z.) 20100101

Title: Medicinal mushrooms: Towards a new horizon.

Journal: Pharmacognosy reviews 20100101

Title: The role of funding and policies on innovation in cancer drug development.

Journal: Ecancermedicalscience 20100101

Title: A review on the rationale and clinical use of concomitant rosuvastatin and fenofibrate/fenofibric acid therapy.

Journal: Clinical pharmacology : advances and applications 20100101

Title: Individualized initiation of statin therapy determined by baseline LDL-C: Are you more likely to achieve goal LDL-C?

Journal: Risk management and healthcare policy 20100101

Title: Treatment of symptomatic HyperLp(a)lipoproteinemia with LDL-apheresis: a multicentre study.

Journal: Atherosclerosis. Supplements 20091229

Title: Reduction in recurrent cardiovascular events with intensive lipid-lowering statin therapy compared with moderate lipid-lowering statin therapy after acute coronary syndromes from the PROVE IT-TIMI 22 (Pravastatin or Atorvastatin Evaluation and Infection Therapy-Thrombolysis In Myocardial Infarction 22) trial.

Journal: Journal of the American College of Cardiology 20091215

Title: Cardiovascular outcomes in randomized trials: should time to first event for 'hard' end points remain the standard approach?

Journal: Journal of the American College of Cardiology 20091215

Title: Effect of intensive statin therapy on clinical outcomes among patients undergoing percutaneous coronary intervention for acute coronary syndrome. PCI-PROVE IT: A PROVE IT-TIMI 22 (Pravastatin or Atorvastatin Evaluation and Infection Therapy-Thrombolysis In Myocardial Infarction 22) Substudy.

Journal: Journal of the American College of Cardiology 20091208

Title: Endothelial function impairment in chronic venous insufficiency: effect of some cardiovascular protectant agents.

Journal: Angiology 20091201

Title: C-reactive protein in the very early phase of acute ischemic stroke: association with poor outcome and death.

Journal: Journal of neurology 20091201

Title: Fluvastatin and lovastatin inhibit granulocyte macrophage-colony stimulating factor-stimulated human eosinophil adhesion to inter-cellular adhesion molecule-1 under flow conditions.

Journal: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20091201

Title: Impact of the PPAR-gamma2 Pro12Ala polymorphism and ACE inhibitor therapy on new-onset microalbuminuria in type 2 diabetes: evidence from BENEDICT.

Journal: Diabetes 20091201

Title: Laboratory and non-laboratory-based risk prediction models for secondary prevention of cardiovascular disease: the LIPID study.

Journal: European journal of cardiovascular prevention and rehabilitation : official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology 20091201

Title: Rediscovering bile acid sequestrants.

Journal: Diabetes, obesity & metabolism 20091201

Title: How do physicians conduct medication reviews?

Journal: Journal of general internal medicine 20091201

Title: SLCO4C1 transporter eliminates uremic toxins and attenuates hypertension and renal inflammation.

Journal: Journal of the American Society of Nephrology : JASN 20091201

Title: Geranylgeraniol prevents the cytotoxic effects of mevastatin in THP-1 cells, without decreasing the beneficial effects on cholesterol synthesis.

Journal: British journal of pharmacology 20091201

Title: Apolipoprotein e genotype, plasma cholesterol, and cancer: a Mendelian randomization study.

Journal: American journal of epidemiology 20091201

Title: The effect of exercise on serum levels of interleukin-18 and components of the metabolic syndrome.

Journal: Metabolic syndrome and related disorders 20091201

Title: HDL as a biomarker, potential therapeutic target, and therapy.

Journal: Diabetes 20091201

Title: Clinical significance of on-treatment triglyceride level in patients treated by percutaneous coronary intervention for non-ST-segment elevation acute coronary syndrome.

Journal: The Korean journal of internal medicine 20091201

Title: Coronary heart disease in moderately hypercholesterolemic, hypertensive black and non-black patients randomized to pravastatin versus usual care: the antihypertensive and lipid lowering to prevent heart attack trial (ALLHAT-LLT).

Journal: American heart journal 20091201

Title: Sitosterol reduces messenger RNA and protein expression levels of Niemann-Pick C1-like 1 in FHs 74 Int cells.

Journal: Nutrition research (New York, N.Y.) 20091201

Title: Statins: in the beginning.

Journal: The journal of the Royal College of Physicians of Edinburgh 20091201

Title: Atrial fibrillation at baseline and during follow-up in ALLHAT (Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial).

Journal: Journal of the American College of Cardiology 20091124

Title: In-vitro release kinetics and stability of anticardiovascular drugs-intercalated layered double hydroxide nanohybrids.

Journal: The journal of physical chemistry. B 20091112

Title: Compactin production studies using Penicillium brevicompactum under solid-state fermentation conditions.

Journal: Applied biochemistry and biotechnology 20091101

Title: Pravastatin prevents miscarriages in antiphospholipid antibody-treated mice.

Journal: Journal of reproductive immunology 20091101

Title: Phylogenetic analysis of Bacillus P450 monooxygenases and evaluation of their activity towards steroids.

Journal: Steroids 20091101

Title: Stimulation of artemisinin synthesis by combined cerebroside and nitric oxide elicitation in Artemisia annua hairy roots.

Journal: Applied microbiology and biotechnology 20091101

Title: Statins block calcific nodule formation of valvular interstitial cells by inhibiting alpha-smooth muscle actin expression.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20091101

Title: The impact of pravastatin therapy on long-term outcome in patients with metabolic syndrome undergoing complete coronary revascularization.

Journal: Circulation journal : official journal of the Japanese Circulation Society 20091101

Title: Comparison of incidences of cardiovascular events among new users of different statins: a retrospective observational cohort study.

Journal: Current medical research and opinion 20091101

Title: Efavirenz: a decade of clinical experience in the treatment of HIV.

Journal: The Journal of antimicrobial chemotherapy 20091101

Title: Quantitative population pharmacokinetic analysis of pravastatin using an enterohepatic circulation model combined with pharmacogenomic Information on SLCO1B1 and ABCC2 polymorphisms.

Journal: Journal of clinical pharmacology 20091101

Title: Novel synthetic inhibitors of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase activity that inhibit tumor cell proliferation and are structurally unrelated to existing statins.

Journal: International journal of molecular medicine 20091101

Title: Effect of pravastatin on nephroprotection in deoxycorticosterone acetate-salt hypertensive rats.

Journal: Journal of hypertension 20091101

Title: Efficacy of aggressive lipid controlling therapy for preventing saphenous vein graft disease.

Journal: The Annals of thoracic surgery 20091101

Title: Bile acids and metabolic regulation: mechanisms and clinical responses to bile acid sequestration.

Journal: Diabetes care 20091101

Title: Triglycerides and HDL cholesterol: stars or second leads in diabetes?

Journal: Diabetes care 20091101

Title: Should all diabetic patients be treated with a statin?

Journal: Diabetes care 20091101

Title: American Diabetes Association indications for statins in diabetes: is there evidence?

Journal: Diabetes care 20091101

Title: Obesity, hyperlipidemia, and metabolic syndrome.

Journal: Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20091101

Title: Statins and colorectal cancer: the jury is still out.

Journal: The American journal of gastroenterology 20091101

Title: Chemistry and biosynthesis of isoprenylated flavonoids from Japanese mulberry tree.

Journal: Proceedings of the Japan Academy. Series B, Physical and biological sciences 20091101

Title: Socioeconomic inequalities in coronary heart disease risk in older age: contribution of established and novel coronary risk factors.

Journal: Journal of thrombosis and haemostasis : JTH 20091101

Title: Management of refractory essential thrombocythemia with anagrelide in a patient undergoing hemodialysis.

Journal: Clinical therapeutics 20091101

Title: Simvastatin inhibits the activation of p21ras and prevents the loss of dopaminergic neurons in a mouse model of Parkinson's disease.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20091028

Title: Complete reconstitution of a highly reducing iterative polyketide synthase.

Journal: Science (New York, N.Y.) 20091023

Title: The SLCO1B1*5 genetic variant is associated with statin-induced side effects.

Journal: Journal of the American College of Cardiology 20091020

Title: Hepatocyte nuclear factor 1alpha plays a critical role in PCSK9 gene transcription and regulation by the natural hypocholesterolemic compound berberine.

Journal: The Journal of biological chemistry 20091016

Title: New highly sensitive enzyme immunoassay for the determination of pravastatin in human plasma.

Journal: Talanta 20091015

Title: Early statin therapy in acute coronary syndromes: the successful cycle of evidence, guidelines, and implementation.

Journal: Journal of the American College of Cardiology 20091006

Title: Skin ulcers and myopathy associated with pravastatin therapy.

Journal: Clinical and experimental dermatology 20091001

Title: Pravastatin and cardiovascular risk in moderate chronic kidney disease.

Journal: Atherosclerosis 20091001

Title: Differential effects of simvastatin and pravastatin on expression of Alzheimer's disease-related genes in human astrocytes and neuronal cells.

Journal: Journal of lipid research 20091001

Title: Low LDL cholesterol, albuminuria, and statins for the risk of cancer in type 2 diabetes: the Hong Kong diabetes registry.

Journal: Diabetes care 20091001

Title: Circulating inflammatory and hemostatic biomarkers are associated with risk of myocardial infarction and coronary death, but not angina pectoris, in older men.

Journal: Journal of thrombosis and haemostasis : JTH 20091001

Title: Suppression in mevalonate synthesis mediates antitumor effects of combined statin and gamma-tocotrienol treatment.

Journal: Lipids 20091001

Title: Prevention of contrast-induced nephropathy by chronic pravastatin treatment in patients with cardiovascular disease and renal insufficiency.

Journal: Journal of cardiology 20091001

Title: Statin therapy and risk of developing type 2 diabetes: a meta-analysis.

Journal: Diabetes care 20091001

Title: Statin-induced diabetes: will it change clinical practice?

Journal: Diabetes care 20091001

Title: Different effects of the ABCG2 c.421C>A SNP on the pharmacokinetics of fluvastatin, pravastatin and simvastatin.

Journal: Pharmacogenomics 20091001

Title: Statins as antiarrhythmics: a systematic review part I: effects on risk of atrial fibrillation.

Journal: Clinical cardiology 20091001

Title: Assessing the effects of weather conditions on physical activity participation using objective measures.

Journal: International journal of environmental research and public health 20091001

Title: Hypolipidemic effects of Monascus-fermented soybean extracts in rats fed a high-fat and -cholesterol diet.

Journal: Journal of agricultural and food chemistry 20090923

Title: Risk factors for stroke and lipid-lowering effect of pravastatin on the risk of stroke in Japanese patients with hypercholesterolemia: analysis of data from the MEGA Study, a large randomized controlled trial.

Journal: Journal of the neurological sciences 20090915

Title: Effects of rosuvastatin on electronegative LDL as characterized by capillary isotachophoresis: the ROSARY Study.

Journal: Journal of lipid research 20090901

Title: The role of transporters in the pharmacokinetics of orally administered drugs.

Journal: Pharmaceutical research 20090901

Title: Characteristic changes in coronary artery at the early hyperglycaemic stage in a rat type 2 diabetes model and the effects of pravastatin.

Journal: British journal of pharmacology 20090901

Title: Chronic treatment with pravastatin prevents early cardiovascular changes in spontaneously hypertensive rats.

Journal: British journal of pharmacology 20090901

Title: Identification of genetic variants associated with response to statin therapy.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20090901

Title: Seasonal variation in lipids: should we consider it more?

Journal: The American journal of cardiology 20090901

Title: The efficacy and safety of ezetimibe and low-dose simvastatin as a primary treatment for dyslipidemia in renal transplant recipients.

Journal: The Korean journal of internal medicine 20090901

Title: Rhabdomyolysis a result of azithromycin and statins: an unrecognized interaction.

Journal: British journal of clinical pharmacology 20090901

Title: The Vytorin on Carotid-Media Thickness and Overall Arterial Rigidity (VYCTOR) study.

Journal: Expert review of cardiovascular therapy 20090901

Title: Inflammatory markers and outcomes in cardiovascular disease.

Journal: PLoS medicine 20090901

Title: [Comparison on long-term effects of atorvastatin or pravastatin combined with clopidogrel for patients undergoing coronary stenting: a randomized controlled trial].

Journal: Zhonghua yi xue za zhi 20090825

Title: Role of tissue factor in a mouse model of thrombotic microangiopathy induced by antiphospholipid antibodies.

Journal: Blood 20090820

Title: Association of leukocyte subtype counts with coronary atherosclerotic regression following pravastatin treatment.

Journal: The American journal of cardiology 20090815

Title: A novel method for oral delivery of apolipoprotein mimetic peptides synthesized from all L-amino acids.

Journal: Journal of lipid research 20090801

Title: Circulating angiopoietin-2 in essential hypertension: relation to atherosclerosis, vascular inflammation, and treatment with olmesartan/pravastatin.

Journal: Journal of hypertension 20090801

Title: Improvement of glucose intolerance by combination of pravastatin and olmesartan in type II diabetic KK-A(y) mice.

Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20090801

Title: Apolipoprotein B but not LDL cholesterol is associated with coronary artery calcification in type 2 diabetic whites.

Journal: Diabetes 20090801

Title: Pravastatin accelerates ischemia-induced angiogenesis through AMP-activated protein kinase.

Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20090801

Title: Application of a 3,3-diphenylpentane skeleton as a multi-template for creation of HMG-CoA reductase inhibitors.

Journal: Bioorganic & medicinal chemistry letters 20090801

Title: Rationale and design of assessment of lipophilic vs. hydrophilic statin therapy in acute myocardial infarction (the ALPS-AMI) study.

Journal: Journal of cardiology 20090801

Title: Tissue distribution of mevalonate pyrophosphate decarboxylase in guinea pig.

Journal: Biological & pharmaceutical bulletin 20090801

Title: Effects of Xuezhikang and pravastatin on circulating endothelial progenitor cells in patients with essential hypertension.

Journal: Chinese journal of integrative medicine 20090801

Title: No significant effect of ABCB1 haplotypes on the pharmacokinetics of fluvastatin, pravastatin, lovastatin, and rosuvastatin.

Journal: British journal of clinical pharmacology 20090801

Title: Balancing potency of platelet inhibition with bleeding risk in the early treatment of acute coronary syndrome.

Journal: The western journal of emergency medicine 20090801

Title: [Effects of pravastatin and granulocyto-colony stimulating factor in mobilizing endothelial progenitor cells in mice with myocardial ischemia].

Journal: Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20090801

Title: Rosuvastatin for cardiovascular prevention: too many uncertainties.

Journal: Prescrire international 20090801

Title: Influence of grapefruit juice on the pharmacokinetics of diltiazem in Wistar rats upon single and multiple dosage regimens.

Journal: Die Pharmazie 20090801

Title: Interventions in the management of serum lipids for preventing stroke recurrence.

Journal: The Cochrane database of systematic reviews 20090708

Title: Rosuvastatin reduces atherosclerotic lesions and promotes progenitor cell mobilisation and recruitment in apolipoprotein E knockout mice.

Journal: Atherosclerosis 20090701

Title: A randomized, multicentre, open-label, parallel-group trial to compare the efficacy and safety profile of daming capsule in patients with hypercholesterolemia.

Journal: Phytotherapy research : PTR 20090701

Title: Mevastatin-induced neurite outgrowth of neuroblastoma cells via activation of EGFR.

Journal: Journal of neuroscience research 20090701

Title: Prevalence of microalbuminuria and associated electrocardiographic abnormalities in an Indo-Asian population.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20090701

Title: Oral pravastatin prolongs survival time of scrapie-infected mice.

Journal: The Journal of general virology 20090701

Title: Additive interaction between the renin-angiotensin system and lipid metabolism for cancer in type 2 diabetes.

Journal: Diabetes 20090701

Title: Common lipid-altering gene variants are associated with therapeutic intervention thresholds of lipid levels in older people.

Journal: European heart journal 20090701

Title: Statins potentiate the in vitro anti-hepatitis C virus activity of selective hepatitis C virus inhibitors and delay or prevent resistance development.

Journal: Hepatology (Baltimore, Md.) 20090701

Title: Statins inhibit the growth of variant human embryonic stem cells and cancer cells in vitro but not normal human embryonic stem cells.

Journal: British journal of pharmacology 20090701

Title: The VYtorin on Carotid intima-media thickness and overall arterial rigidity (VYCTOR) study.

Journal: Journal of clinical pharmacology 20090701

Title: Effects of combined olmesartan and pravastatin on glucose intolerance and cardiovascular remodeling in a metabolic-syndrome model.

Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20090701

Title: Combination treatment to prevent atherosclerosis.

Journal: Hypertension (Dallas, Tex. : 1979) 20090701

Title: Low HDL cholesterol is associated with the risk of stroke in elderly diabetic individuals: changes in the risk for atherosclerotic diseases at various ages.

Journal: Diabetes care 20090701

Title: Safety and tolerability of dalcetrapib.

Journal: The American journal of cardiology 20090701

Title: Long-term efficacy of upstream therapy using angiotensin-converting enzyme inhibitors and statins in combination with antiarrhythmic agents for the treatment of paroxysmal atrial fibrillation.

Journal: International heart journal 20090701

Title: Effect of precultural and nutritional parameters on compactin production by solid-state fermentation.

Journal: Journal of microbiology and biotechnology 20090701

Title: [Simvastatin-induced dermatomyositis].

Journal: Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete 20090601

Title: Differential metabolic effects of pravastatin and simvastatin in hypercholesterolemic patients.

Journal: Atherosclerosis 20090601

Title: Heterologous expression, purification, and characterization of cytochrome P450sca-2 and mutants with improved solubility in Escherichia coli.

Journal: Protein expression and purification 20090601

Title: Functional analysis of a mutation in the SLCO1B1 gene (c.1628T>G) identified in a Japanese patient with pravastatin-induced myopathy.

Journal: The pharmacogenomics journal 20090601

Title: Effect of bile acids on the biliary excretion of pravastatin in rats.

Journal: Hepatology research : the official journal of the Japan Society of Hepatology 20090601

Title: Effects of rosuvastatin and atorvastatin on LDL and HDL particle concentrations in patients with metabolic syndrome: a randomized, double-blind, controlled study.

Journal: Diabetes care 20090601

Title: MlcR, a zinc cluster activator protein, is able to bind to a single (A/T)CGG site of cognate asymmetric motifs in the ML-236B (compactin) biosynthetic gene cluster.

Journal: Molecular genetics and genomics : MGG 20090601

Title: Improvement of compactin (ML-236B) production by genetic engineering in compactin high-producing Penicillium citrinum.

Journal: Applied microbiology and biotechnology 20090601

Title: Oral apolipoprotein A-I mimetic peptide improves cognitive function and reduces amyloid burden in a mouse model of Alzheimer's disease.

Journal: Neurobiology of disease 20090601

Title: Combined treatment of gamma-tocotrienol with statins induce mammary tumor cell cycle arrest in G1.

Journal: Experimental biology and medicine (Maywood, N.J.) 20090601

Title: [Effect of intensive treatment with atorvastatin versus standard doses of statins on the risk of stroke. A meta-analysis from five randomized trials including 25,709 patients].

Journal: Revista de neurologia 20090601

Title: Conversion to tacrolimus and atorvastatin in cyclosporine-treated heart transplant recipients with dyslipidemia refractory to fluvastatin.

Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20090601

Title: Pleiotropic phenotypes caused by an opal nonsense mutation in an essential gene encoding HMG-CoA reductase in fission yeast.

Journal: Genes to cells : devoted to molecular & cellular mechanisms 20090601

Title: Established and newly proposed mechanisms of chronic cyclosporine nephropathy.

Journal: The Korean journal of internal medicine 20090601

Title: Are markers of inflammation more strongly associated with risk for fatal than for nonfatal vascular events?

Journal: PLoS medicine 20090601

Title: Association of body mass index with coronary plaque regression: 6-month prospective study.

Journal: Journal of atherosclerosis and thrombosis 20090601

Title: Effects of a concomitant single oral dose of rifampicin on the pharmacokinetics of pravastatin in a two-phase, randomized, single-blind, placebo-controlled, crossover study in healthy Chinese male subjects.

Journal: Clinical therapeutics 20090601

Title: Adenosine and adenosine receptors: Newer therapeutic perspective.

Journal: Indian journal of pharmacology 20090601

Title: Effect of intensive lipid-lowering therapy on telomere erosion in endothelial progenitor cells obtained from patients with coronary artery disease.

Journal: Clinical science (London, England : 1979) 20090501

Title: Pravastatin limits radiation-induced vascular dysfunction in the skin.

Journal: The Journal of investigative dermatology 20090501

Title: PPAR gamma variant influences angiographic outcome and 10-year cardiovascular risk in male symptomatic coronary artery disease patients.

Journal: Diabetes care 20090501

Title: Coenzyme Q10 improves endothelial dysfunction in statin-treated type 2 diabetic patients.

Journal: Diabetes care 20090501

Title: Digoxin and ouabain increase the synthesis of cholesterol in human liver cells.

Journal: Cellular and molecular life sciences : CMLS 20090501

Title: Fluvastatin improves osteoporosis in fructose-fed insulin resistant model rats through blockade of the classical mevalonate pathway and antioxidant action.

Journal: International journal of molecular medicine 20090501

Title: Complete blockage of the mevalonate pathway results in male gametophyte lethality.

Journal: Journal of experimental botany 20090501

Title: Effect of atorvastatin on microRNA 221 / 222 expression in endothelial progenitor cells obtained from patients with coronary artery disease.

Journal: European journal of clinical investigation 20090501

Title: The effect of nine common polymorphisms in coagulation factor genes (F2, F5, F7, F12 and F13 ) on the effectiveness of statins: the GenHAT study.

Journal: Pharmacogenetics and genomics 20090501

Title: Re: Statin-induced bone morphogenetic protein (BMP) 2 expression during bone regeneration: an immunohistochemical study.

Journal: Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 20090501

Title: Effect of procainization of ventromedial nucleus of hypothalamus on the feeding behavior of rats.

Journal: Journal of clinical biochemistry and nutrition 20090501

Title: Rhabdomyolysis in an HIV-infected patient on anti-retroviral therapy precipitated by high-dose pravastatin.

Journal: Current drug safety 20090501

Title: Managing toxicities and optimal dosing of targeted drugs in advanced kidney cancer.

Journal: Current oncology (Toronto, Ont.) 20090501

Title: Asymmetric dimethylarginine (ADMA) and endothelial dysfunction: implications for atherogenesis.

Journal: Clinics (Sao Paulo, Brazil) 20090501

Title: Trypanosoma cruzi: participation of cholesterol and placental alkaline phosphatase in the host cell invasion.

Journal: Experimental parasitology 20090501

Title: Effect of R219K polymorphism of the ABCA1 gene on the lipid-lowering effect of pravastatin in Chinese patients with coronary heart disease.

Journal: Clinical and experimental pharmacology & physiology 20090501

Title: Pravastatin prevents miscarriages in mice: role of tissue factor in placental and fetal injury.

Journal: Blood 20090423

Title: Efficient biotransformations using Escherichia coli with tolC acrAB mutations expressing cytochrome P450 genes.

Journal: Bioscience, biotechnology, and biochemistry 20090423

Title: Seasonal variation in lipids in patients following acute coronary syndrome on fixed doses of Pravastatin (40 mg) or Atorvastatin (80 mg) (from the Pravastatin or Atorvastatin Evaluation and Infection Therapy-Thrombolysis In Myocardial Infarction 22 [PROVE IT-TIMI 22] Study).

Journal: The American journal of cardiology 20090415

Title: Statins for the prevention of dementia.

Journal: The Cochrane database of systematic reviews 20090415

Title: Pravastatin attenuates interferon-gamma action via modulation of STAT1 to prevent aortic atherosclerosis in apolipoprotein E-knockout mice.

Journal: Clinical and experimental pharmacology & physiology 20090401

Title: The synergistic inhibition of atherogenesis in apoE-/- mice between pravastatin and the sPLA2 inhibitor varespladib (A-002).

Journal: Journal of lipid research 20090401

Title: C-reactive protein and 5-year survival in type 2 diabetes: the Casale Monferrato Study.

Journal: Diabetes 20090401

Title: Statin therapy is associated with lower total but not bioavailable or free testosterone in men with type 2 diabetes.

Journal: Diabetes care 20090401

Title: Alanine aminotransferase, gamma-glutamyltransferase, and incident diabetes: the British Women's Heart and Health Study and meta-analysis.

Journal: Diabetes care 20090401

Title: A test of the lipostat theory in a seasonal (ovine) model under natural conditions reveals a close relationship between adiposity and melanin concentrating hormone expression.

Journal: Domestic animal endocrinology 20090401

Title: Rhabdomyolysis reports show interaction between simvastatin and CYP3A4 inhibitors.

Journal: Pharmacoepidemiology and drug safety 20090401

Title: Antihypertensive therapy, new-onset diabetes, and cardiovascular disease.

Journal: International journal of clinical practice 20090401

Title: Preoperative statin use and infection after cardiac surgery: a cohort study.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20090401

Title: Statins may not protect against vasospasm in subarachnoid haemorrhage.

Journal: Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 20090401

Title: Potentiated cytotoxic effects of statins and ajoene in murine melanoma cells.

Journal: Melanoma research 20090401

Title: Towards prediction of metabolic products of polyketide synthases: an in silico analysis.

Journal: PLoS computational biology 20090401

Title: Personalized medicine in coronary artery disease: insights from genomic research.

Journal: Korean circulation journal 20090401

Title: Rosuvastatin in patients with elevated C-reactive protein.

Journal: The New England journal of medicine 20090305

Title: Effects of pravastatin on functional capacity in patients with chronic obstructive pulmonary disease and pulmonary hypertension.

Journal: Clinical science (London, England : 1979) 20090301

Title: Role of pravastatin in pulmonary hypertension in chronic obstructive pulmonary disease.

Journal: Clinical science (London, England : 1979) 20090301

Title: Use of sandwich-cultured human hepatocytes to predict biliary clearance of angiotensin II receptor blockers and HMG-CoA reductase inhibitors.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20090301

Title: Molecular beacons can assess changes in expression and 3'-polyadenylation of human eNOS mRNA.

Journal: American journal of physiology. Cell physiology 20090301

Title: Prognostic utility of apoB/AI, total cholesterol/HDL, non-HDL cholesterol, or hs-CRP as predictors of clinical risk in patients receiving statin therapy after acute coronary syndromes: results from PROVE IT-TIMI 22.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20090301

Title: Metabolic syndrome abating the beneficial effect of pravastatin treatment on adhesion of endothelium by monocytes in subjects with hypercholesterolemia.

Journal: Metabolism: clinical and experimental 20090301

Title: Strategies for blocking the fibrogenic actions of connective tissue growth factor (CCN2): From pharmacological inhibition in vitro to targeted siRNA therapy in vivo.

Journal: Journal of cell communication and signaling 20090301

Title: The carotenogenesis pathway via the isoprenoid-beta-carotene interference approach in a new strain of Dunaliella salina isolated from Baja California Mexico.

Journal: Marine drugs 20090301

Title: [Atorvastatin in secondary prevention].

Journal: Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir 20090301

Title: Mevinolin enhances osteogenic genes (ALP, type I collagen and osteocalcin), CD44, CD47 and CD51 expression during osteogenic differentiation.

Journal: Life sciences 20090227

Title: [Statin therapy and muscle disorders].

Journal: Orvosi hetilap 20090208

Title: [Comment from the cardiologic viewpoint].

Journal: Praxis 20090204

Title: 3-Hydroxy-3-methylglutaryl (HMG)-COA reductase inhibitors and phosphodiesterase type V inhibitors attenuate right ventricular pressure and remodeling in a rat model of pulmonary hypertension.

Journal: Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20090204

Title: Mevastatin reduces cartilage degradation in rabbit experimental osteoarthritis through inhibition of synovial inflammation.

Journal: Osteoarthritis and cartilage 20090201

Title: Pitfalls in the design and analysis of paediatric clinical trials: a case of a 'failed' multi-centre study, and potential solutions.

Journal: Acta paediatrica (Oslo, Norway : 1992) 20090201

Title: Adipocytokines and risk of stroke in older people: a nested case-control study.

Journal: International journal of epidemiology 20090201

Title: Effects of high-dose simvastatin therapy on glucose metabolism and ectopic lipid deposition in nonobese type 2 diabetic patients.

Journal: Diabetes care 20090201

Title: Physiologically based pharmacokinetic modeling to predict transporter-mediated clearance and distribution of pravastatin in humans.

Journal: The Journal of pharmacology and experimental therapeutics 20090201

Title: Leptin predicts diabetes but not cardiovascular disease: results from a large prospective study in an elderly population.

Journal: Diabetes care 20090201

Title: Are elevated circulating intercellular adhesion molecule 1 levels more strongly predictive of diabetes than vascular risk? Outcome of a prospective study in the elderly.

Journal: Diabetologia 20090201

Title: Importance of Rac1 signaling pathway inhibition in the pleiotropic effects of HMG-CoA reductase inhibitors.

Journal: Circulation journal : official journal of the Japanese Circulation Society 20090201

Title: Fate and distribution of pharmaceuticals in wastewater and sewage sludge of the conventional activated sludge (CAS) and advanced membrane bioreactor (MBR) treatment.

Journal: Water research 20090201

Title: Pravastatin for cardiovascular event primary prevention in patients with mild-to-moderate hypertension in the Management of Elevated Cholesterol in the Primary Prevention Group of Adult Japanese (MEGA) Study.

Journal: Hypertension (Dallas, Tex. : 1979) 20090201

Title: Treatment with statin on atheroma regression evaluated by intravascular ultrasound with Virtual Histology (TRUTH Study): rationale and design.

Journal: Circulation journal : official journal of the Japanese Circulation Society 20090201

Title: Effects of pravastatin on the function of dendritic cells in patients with coronary heart disease.

Journal: Basic & clinical pharmacology & toxicology 20090201

Title: Absorption of montelukast is transporter mediated: a common variant of OATP2B1 is associated with reduced plasma concentrations and poor response.

Journal: Pharmacogenetics and genomics 20090201

Title: Should high creatine kinase discourage the initiation or continuance of statins for the treatment of hypercholesterolemia?

Journal: Metabolism: clinical and experimental 20090201

Title: Controversial role of plant sterol esters in the management of hypercholesterolaemia.

Journal: European heart journal 20090201

Title: [Pharmacogenomics: inter-ethnic and intra-ethnic differences in pharmacokinetic and pharmacodynamic profiles of clinically relevant drugs].

Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20090201

Title: Perceived medication adverse effects and coping strategies reported by chronic heart failure patients.

Journal: International journal of clinical practice 20090201

Title: Co-medication of statins and CYP3A4 inhibitors before and after introduction of new reimbursement policy.

Journal: British journal of clinical pharmacology 20090201

Title: The relationship between reduction in low-density lipoprotein cholesterol by statins and reduction in risk of cardiovascular outcomes: an updated meta-analysis.

Journal: Clinical therapeutics 20090201

Title: The effect of dyslipidemic drugs on mortality: A meta-analysis.

Journal: Indian journal of pharmacology 20090201

Title: Pravastatin improves function in hibernating myocardium by mobilizing CD133+ and cKit+ bone marrow progenitor cells and promoting myocytes to reenter the growth phase of the cardiac cell cycle.

Journal: Circulation research 20090130

Title: The cornucopia of 'pleiotropic' actions of statins: myogenesis as a new mechanism for statin-induced benefits?

Journal: Circulation research 20090130

Title: No effect of statins on biochemical outcomes after radiotherapy for localized prostate cancer.

Journal: Urology 20090101

Title: Pravastatin, a 3-hydroxy-3-methyl-glutharyl coenzyme A inhibitor does not show pleiotropic effects in patients with systemic lupus erythematosus.

Journal: Rheumatology international 20090101

Title: Statin-induced bone morphogenetic protein (BMP) 2 expression during bone regeneration: an immunohistochemical study.

Journal: Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 20090101

Title: Statin ameliorates hypoxia-induced pulmonary hypertension associated with down-regulated stromal cell-derived factor-1.

Journal: Cardiovascular research 20090101

Title: Randomized placebo-controlled trial assessing a treatment strategy consisting of pravastatin, vitamin E, and homocysteine lowering on plasma asymmetric dimethylarginine concentration in mild to moderate CKD.

Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 20090101

Title: Pravastatin attenuates allergic airway inflammation by suppressing antigen sensitisation, interleukin 17 production and antigen presentation in the lung.

Journal: Thorax 20090101

Title: Statins alter neutrophil migration by modulating cellular Rho activity--a potential mechanism for statins-mediated pleotropic effects?

Journal: Journal of leukocyte biology 20090101

Title: Clopidogrel: review of bioanalytical methods, pharmacokinetics/pharmacodynamics, and update on recent trends in drug-drug interaction studies.

Journal: Biomedical chromatography : BMC 20090101

Title: Aspergillus westerdijkiae polyketide synthase gene 'aoks1' is involved in the biosynthesis of ochratoxin A.

Journal: Fungal genetics and biology : FG & B 20090101

Title: Complete assignment of 1H and 13C NMR data of pravastatin derivatives.

Journal: Magnetic resonance in chemistry : MRC 20090101

Title: Leptin, but not adiponectin, is a predictor of recurrent cardiovascular events in men: results from the LIPID study.

Journal: International journal of obesity (2005) 20090101

Title: Trends in the use of lipid-lowering medications at discharge in patients with acute myocardial infarction: 1998 to 2006.

Journal: American heart journal 20090101

Title: Competitive substrates for P-glycoprotein and organic anion protein transporters differentially reduce blood organ transport of fentanyl and loperamide: pharmacokinetics and pharmacodynamics in Sprague-Dawley rats.

Journal: Anesthesia and analgesia 20090101

Title: The effects of Thiazolidinediones on metabolic complications and Lipodystrophy in HIV-infected patients.

Journal: PPAR research 20090101

Title: Standards of medical care in diabetes--2009.

Journal: Diabetes care 20090101

Title: [Effect of the brand and generic medicine of pravastatin on dyslipidemia in rabbits fed a high cholesterol diet].

Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20090101

Title: Possible mechanisms underlying statin-induced skeletal muscle toxicity in L6 fibroblasts and in rats.

Journal: Journal of pharmacological sciences 20090101

Title: Use of Framingham risk score and new biomarkers to predict cardiovascular mortality in older people: population based observational cohort study.

Journal: BMJ (Clinical research ed.) 20090101

Title: Iron behaving badly: inappropriate iron chelation as a major contributor to the aetiology of vascular and other progressive inflammatory and degenerative diseases.

Journal: BMC medical genomics 20090101

Title: The plastidial 2-C-methyl-D-erythritol 4-phosphate pathway provides the isoprenyl moiety for protein geranylgeranylation in tobacco BY-2 cells.

Journal: The Plant cell 20090101

Title: Atorvastatin ameliorates cerebral vasospasm and early brain injury after subarachnoid hemorrhage and inhibits caspase-dependent apoptosis pathway.

Journal: BMC neuroscience 20090101

Title: Reduced glomerular filtration rate and its association with clinical outcome in older patients at risk of vascular events: secondary analysis.

Journal: PLoS medicine 20090101

Title: An account of cloned genes of Methyl-erythritol-4-phosphate pathway of isoprenoid biosynthesis in plants.

Journal: Current issues in molecular biology 20090101

Title: Association between change in high density lipoprotein cholesterol and cardiovascular disease morbidity and mortality: systematic review and meta-regression analysis.

Journal: BMJ (Clinical research ed.) 20090101

Title: A-002 (Varespladib), a phospholipase A2 inhibitor, reduces atherosclerosis in guinea pigs.

Journal: BMC cardiovascular disorders 20090101

Title: [Primary prevention trial by lowering hyperlipidemia on the cardiovascular disease (MEGA Study)].

Journal: Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics 20090101

Title: In vitro-in vivo extrapolation of transporter-mediated clearance in the liver and kidney.

Journal: Drug metabolism and pharmacokinetics 20090101

Title: Neural differentiation potential of human bone marrow-derived mesenchymal stromal cells: misleading marker gene expression.

Journal: BMC neuroscience 20090101

Title: Effects of statins on the secretion of human serum albumin in cultured HepG2 cells.

Journal: Journal of biomedical science 20090101

Title: Rosuvastatin-induced rhabdomyolysis probably via CYP2C9 saturation.

Journal: Drug metabolism and drug interactions 20090101

Title: Lifestyle-induced metabolic inflexibility and accelerated ageing syndrome: insulin resistance, friend or foe?

Journal: Nutrition & metabolism 20090101

Title: Sociodemographic variations in the contribution of secondary drug prevention to stroke survival at middle and older ages: cohort study.

Journal: BMJ (Clinical research ed.) 20090101

Title: Identification, expression, and functional characterization of full-length and splice variants of murine organic anion transporting polypeptide 1b2.

Journal: Molecular pharmaceutics 20090101

Title: Impact of ezetimibe on cholesterol subfractions in dyslipidemic cardiac transplant recipients receiving statin therapy.

Journal: Clinical transplantation 20090101

Title: OxDBase: a database of oxygenases involved in biodegradation.

Journal: BMC research notes 20090101

Title: Evidence synthesis as the key to more coherent and efficient research.

Journal: BMC medical research methodology 20090101

Title: Atorvastatin reduces plasma levels of chemokine (CXCL10) in patients with Crohn's disease.

Journal: PloS one 20090101

Title: Ten-Year Survival in 75-Year-Old Men and Women: Predictive Ability of Total Cholesterol, HDL-C, and LDL-C.

Journal: Current gerontology and geriatrics research 20090101

Title: Role of atazanavir in the treatment of HIV infection.

Journal: Therapeutics and clinical risk management 20090101

Title: Efficacy and safety of rosuvastatin in the management of dyslipidemia.

Journal: Vascular health and risk management 20090101

Title: Prevention of atherosclerosis in patients living with HIV.

Journal: Vascular health and risk management 20090101

Title: Management of complex lipid abnormalities with a fixed dose combination of simvastatin and extended release niacin.

Journal: Vascular health and risk management 20090101

Title: The effect of angiotensin receptor blockers on C-reactive protein and other circulating inflammatory indices in man.

Journal: Vascular health and risk management 20090101

Title: Dyslipidemia treatment of patients with diabetes mellitus in a US managed care plan: a retrospective database analysis.

Journal: Cardiovascular diabetology 20090101

Title: Pharmacological Treatment of Alzheimer's Disease: Is it Progressing Adequately?

Journal: The open neurology journal 20090101

Title: Efficacy, effectiveness and real life goal attainment of statins in managing cardiovascular risk.

Journal: Vascular health and risk management 20090101

Title: Fixed combination of amlodipine and atorvastatin in cardiovascular risk management: patient perspectives.

Journal: Vascular health and risk management 20090101

Title: Impact of statins and ACE inhibitors on mortality after COPD exacerbations.

Journal: Respiratory research 20090101

Title: ACE (I/D) polymorphism and response to treatment in coronary artery disease: a comprehensive database and meta-analysis involving study quality evaluation.

Journal: BMC medical genetics 20090101

Title: Lipid rafts and clathrin cooperate in the internalization of PrP in epithelial FRT cells.

Journal: PloS one 20090101

Title: The biosynthesis and accumulation of beta-carotene in Dunaliella salina proceed via the glyceraldehyde 3-phosphate/pyruvate pathway.

Journal: Natural product research 20090101

Title: Statins and erectile dysfunction: results of a case/non-case study using the French Pharmacovigilance System Database.

Journal: Drug safety 20090101

Title: Statin use and risk of community acquired pneumonia in older people: population based case-control study.

Journal: BMJ (Clinical research ed.) 20090101

Title: Prevalence of transcription promoters within archaeal operons and coding sequences.

Journal: Molecular systems biology 20090101

Title: Antiretroviral effect of lovastatin on HIV-1-infected individuals without highly active antiretroviral therapy (The LIVE study): a phase-II randomized clinical trial.

Journal: Trials 20090101

Title: Reducing morbidity and mortality in high risk patients with statins.

Journal: Vascular health and risk management 20090101

Title: Treatment of pediatric pulmonary hypertension.

Journal: Vascular health and risk management 20090101

Title: The link between human and transgenic animal studies involving postprandial hypertriglyceridemia and CETP gene polymorphisms.

Journal: The open cardiovascular medicine journal 20090101

Title: Implementation of guidelines for the management of arterial hypertension. The impulsion study.

Journal: The open cardiovascular medicine journal 20090101

Title: Effects of cardiovascular lifestyle change on lipoprotein subclass profiles defined by nuclear magnetic resonance spectroscopy.

Journal: Lipids in health and disease 20090101

Title: The benefits of statins in people without established cardiovascular disease but with cardiovascular risk factors: meta-analysis of randomised controlled trials.

Journal: BMJ (Clinical research ed.) 20090101

Title: Kidney function and estimated vascular risk in patients with primary dyslipidemia.

Journal: The open cardiovascular medicine journal 20090101

Title: Pleiotropic effects of statins in atrial fibrillation patients: the evidence.

Journal: Vascular health and risk management 20090101

Title: Associations between statins and COPD: a systematic review.

Journal: BMC pulmonary medicine 20090101

Title: Statin-induced calcification in human mesenchymal stem cells is cell death related.

Journal: Journal of cellular and molecular medicine 20090101

Title: Effect of rosiglitazone on progression of atherosclerosis: insights using 3D carotid cardiovascular magnetic resonance.

Journal: Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance 20090101

Title: Regulation of bile acid and cholesterol metabolism by PPARs.

Journal: PPAR research 20090101

Title: New options in the treatment of lipid disorders in HIV-infected patients.

Journal: The open AIDS journal 20090101

Title: Characteristics, management and attainment of lipid target levels in diabetic and cardiac patients enrolled in Disease Management Program versus those in routine care: LUTZ registry.

Journal: BMC public health 20090101

Title: Sterol Biosynthesis Pathway as Target for Anti-trypanosomatid Drugs.

Journal: Interdisciplinary perspectives on infectious diseases 20090101

Title: Managing treatment-experienced pediatric and adolescent HIV patients: role of darunavir.

Journal: Therapeutics and clinical risk management 20090101

Title: RhoA/Rho-kinase signaling: a therapeutic target in pulmonary hypertension.

Journal: Vascular health and risk management 20090101

Title: Mood stabilizer therapy and pravastatin: higher risk for adverse skin reactions?

Journal: Acta medica (Hradec Kralove) 20090101

Title: Conjugated linoleic acids as functional food: an insight into their health benefits.

Journal: Nutrition & metabolism 20090101

Title: Lipoprotein ratios: Physiological significance and clinical usefulness in cardiovascular prevention.

Journal: Vascular health and risk management 20090101

Title: Antiatherogenic effects of vitamin E: the search for the Holy Grail.

Journal: Vascular health and risk management 20090101

Title: Drugs associated with more suicidal ideations are also associated with more suicide attempts.

Journal: PloS one 20090101

Title: An editor for pathway drawing and data visualization in the Biopathways Workbench.

Journal: BMC systems biology 20090101

Title: Thinking beyond low-density lipoprotein cholesterol: strategies to further reduce cardiovascular risk.

Journal: Vascular health and risk management 20090101

Title: Apoptosis of lens epithelial cells induced by high concentration of glucose is associated with a decrease in caveolin-1 levels.

Journal: Molecular vision 20090101

Title: Statin prophylaxis and inflammatory mediators following cardiopulmonary bypass: a systematic review.

Journal: Critical care (London, England) 20090101

Title: Effects of increasing the dose of pravastatin on serum adiponectin level in Japanese mild hypercholesterolemic and hypertensive patients.

Journal: Arzneimittel-Forschung 20090101

Title: Candidate genetic analysis of plasma high-density lipoprotein-cholesterol and severity of coronary atherosclerosis.

Journal: BMC medical genetics 20090101

Title: The impact of statins on health services utilization and mortality in older adults discharged from hospital with ischemic heart disease: a cohort study.

Journal: BMC health services research 20090101

Title: Long-term prediction of fish growth under varying ambient temperature using a multiscale dynamic model.

Journal: BMC systems biology 20090101

Title: Pleiotropic vasoprotective effects of statins: the chicken or the egg?

Journal: Drug design, development and therapy 20090101

Title: Hypercholesterolemia and myocardial function evaluated via tissue doppler imaging.

Journal: Cardiovascular ultrasound 20090101

Title: Analysis of recently identified dyslipidemia alleles reveals two loci that contribute to risk for carotid artery disease.

Journal: Lipids in health and disease 20090101

Title: Prediction of pharmacological and xenobiotic responses to drugs based on time course gene expression profiles.

Journal: PloS one 20090101

Title: Influenza morbidity and mortality in elderly patients receiving statins: a cohort study.

Journal: PloS one 20090101

Title: Management of dyslipidemia in children.

Journal: Diabetology & metabolic syndrome 20090101

Title: Critical appraisal of the role of pitavastatin in treating dyslipidemias and achieving lipid goals.

Journal: Vascular health and risk management 20090101

Title: [Achievement of blood lipid target levels with Ezetimibe/Simvastatin in patients with atherosclerosis and/or diabetes mellitus--an Austrian observational study].

Journal: Wiener medizinische Wochenschrift (1946) 20090101

Title: Universal health care no guarantee of equity: comparison of socioeconomic inequalities in the receipt of coronary procedures in patients with acute myocardial infarction and angina.

Journal: BMC public health 20090101

Title: SWiss Atorvastatin and interferon Beta-1b trial In Multiple Sclerosis (SWABIMS)--rationale, design and methodology.

Journal: Trials 20090101

Title: Cardiovascular magnetic resonance in carotid atherosclerotic disease.

Journal: Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance 20090101

Title: Statin research in critical illness: hampered by poor trial design?

Journal: Critical care (London, England) 20090101

Title: Comparison of the efficacy of administering a combination of ezetimibe plus fenofibrate versus atorvastatin monotherapy in the treatment of dyslipidemia.

Journal: Lipids in health and disease 20090101

Title: Adolescent type 1 Diabetes Cardio-renal Intervention Trial (AdDIT).

Journal: BMC pediatrics 20090101

Title: An electronic clinical decision support tool to assist primary care providers in cardiovascular disease risk management: development and mixed methods evaluation.

Journal: Journal of medical Internet research 20090101

Title: Investigating the effects of statins on cellular lipid metabolism using a yeast expression system.

Journal: PloS one 20090101

Title: Cholesterol homeostasis in two commonly used human prostate cancer cell-lines, LNCaP and PC-3.

Journal: PloS one 20090101

Title: The JUPITER and AURORA clinical trials for rosuvastatin in special primary prevention populations: perspectives, outcomes, and consequences.

Journal: Vascular health and risk management 20090101

Title: Nitric oxide and coronary vascular endothelium adaptations in hypertension.

Journal: Vascular health and risk management 20090101

Title: Norepinephrine transporter is involved in down-regulation of beta1-adrenergic receptors caused by adjuvant arthritis.

Journal: Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20090101

Title: Pharmacogenomic insights into treatment and management of statin-induced myopathy.

Journal: Genome medicine 20090101

Title: A Multidisciplinary Investigation to Determine the Structure and Source of Dimeric Impurities in AMG 517 Drug Substance.

Journal: International journal of analytical chemistry 20090101

Title: A comparative evaluation of safety and efficacy of rosuvastatin, simvastatin, and atorvastatin in patients of type 2 diabetes mellitus with dyslipidemia.

Journal: International journal of diabetes in developing countries 20090101

Title: A HMGCR polymorphism is associated with relations between blood pressure and urinary sodium and potassium ratio in the Epic-Norfolk Study.

Journal: Journal of the American Society of Hypertension : JASH 20090101

Title: Epidemiologic characteristics and risk factors for renal cell cancer.

Journal: Clinical epidemiology 20090101

Title: New oral disease-modifying therapies for multiple sclerosis.

Journal: F1000 medicine reports 20090101

Title: Improving glycemic and cholesterol control through an integrated approach incorporating colesevelam - a clinical perspective.

Journal: Diabetes, metabolic syndrome and obesity : targets and therapy 20090101

Title: The use of everolimus in renal-transplant patients.

Journal: International journal of nephrology and renovascular disease 20090101

Title: Long-term use of rosuvastatin: a critical risk benefit appraisal and comparison with other antihyperlipidemics.

Journal: Drug, healthcare and patient safety 20090101

Title: Improvement in sleep apnoea associated with switch from simvastatin to pravastatin.

Journal: BMJ case reports 20090101

Title: Effects of antihypertensive drugs on carotid intima-media thickness: Focus on angiotensin II receptor blockers. A review of randomized, controlled trials.

Journal: Integrated blood pressure control 20090101

Title: Safety and efficacy of statin therapy in patients switched from cyclosporine a to sirolimus after cardiac transplantation.

Journal: Transplantation 20081227

Title: Berberine decreases PCSK9 expression in HepG2 cells.

Journal: Atherosclerosis 20081201

Title: Reduction of charge-modified LDL by statin therapy in patients with CHD or CHD risk factors and elevated LDL-C levels: the SPECIAL Study.

Journal: Atherosclerosis 20081201

Title: Overexpression of RhoA enhances peritoneal dissemination: RhoA suppression with Lovastatin may be useful for ovarian cancer.

Journal: Cancer science 20081201

Title: Does low to moderate alcohol intake protect against cognitive decline in older people?

Journal: Journal of the American Geriatrics Society 20081201

Title: Tolerability and effects on lipids of ezetimibe coadministered with pravastatin or simvastatin for twelve months: results from two open-label extension studies in hypercholesterolemic patients.

Journal: Clinical therapeutics 20081201

Title: Managing hypercholesterolemia and its correlation with carotid plaque morphology in patients undergoing carotid endarterectomy.

Journal: Vascular health and risk management 20081201

Title: Achieving lipid goals with rosuvastatin compared with simvastatin in high risk patients in real clinical practice: a randomized, open-label, parallel-group, multi-center study: the DISCOVERY-Beta study.

Journal: Vascular health and risk management 20081201

Title: Dysfunctional regulation of ocular blood flow: A risk factor for glaucoma?

Journal: Clinical ophthalmology (Auckland, N.Z.) 20081201

Title: Pharmacogenetic predictors of statin-mediated low-density lipoprotein cholesterol reduction and dose response.

Journal: Circulation. Cardiovascular genetics 20081201

Title: Rosuvastatin reduces non-high-density lipoprotein cholesterol and lipoprotein remnants in patients with dysbetalipoproteinemia (Fredrickson type III hyperlipoproteinemia).

Journal: Journal of clinical lipidology 20081201

Title: Concomitant use of statins and CYP3A4 inhibitors in administrative claims and electronic medical records databases.

Journal: Journal of clinical lipidology 20081201

Title: Primary prevention of cardiovascular mortality and events with statin treatments: a network meta-analysis involving more than 65,000 patients.

Journal: Journal of the American College of Cardiology 20081125

Title: Statins and blood pressure.

Journal: Archives of internal medicine 20081124

Title: The influence of statin medications on prostate-specific antigen levels.

Journal: Journal of the National Cancer Institute 20081105

Title: Statin suppresses apoptosis in osteoblastic cells: role of transforming growth factor-beta-Smad3 pathway.

Journal: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20081101

Title: Improved survival of diabetic foot ulcer patients 1995-2008: possible impact of aggressive cardiovascular risk management.

Journal: Diabetes care 20081101

Title: Impact of adherence to statins on chronic heart failure in primary prevention.

Journal: British journal of clinical pharmacology 20081101

Title: An evaluation of a data mining signal for amyotrophic lateral sclerosis and statins detected in FDA's spontaneous adverse event reporting system.

Journal: Pharmacoepidemiology and drug safety 20081101

Title: CETP genotype predicts increased mortality in statin-treated men with proven cardiovascular disease: an adverse pharmacogenetic interaction.

Journal: European heart journal 20081101

Title: Cloning of the dog bile salt export pump (BSEP; ABCB11) and functional comparison with the human and rat proteins.

Journal: Biopharmaceutics & drug disposition 20081101

Title: Rosuvastatin, pravastatin, and atorvastatin for the treatment of hypercholesterolaemia in HIV-infected patients receiving protease inhibitors.

Journal: Current HIV research 20081101

Title: [67-year-old patient with speech disorder and dysphagia].

Journal: Deutsche medizinische Wochenschrift (1946) 20081101

Title: The efficacy and safety of ezetimibe for treatment of dyslipidemia after heart transplantation.

Journal: Transplantation proceedings 20081101

Title: Transition of psoriasiform drug eruption to psoriasis de novo evidenced by histopathology.

Journal: The Journal of dermatology 20081101

Title: Pravastatin prevents aortic atherosclerosis via modulation of signal transduction and activation of transcription 3 (STAT3) to attenuate interleukin-6 (IL-6) action in ApoE knockout mice.

Journal: International journal of molecular sciences 20081101

Title: The role of novel biomarkers of cardiovascular disease in chronic kidney disease: focus on adiponectin and leptin.

Journal: Current cardiology reviews 20081101

Title: Decreased plasma and cardiac matrix metalloproteinase activities in patients with coronary artery disease and treated with pravastatin.

Journal: European journal of pharmacology 20081010

Title: Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.

Journal: Journal of medicinal chemistry 20081009

Title: Lovastatin, but not pravastatin, limits in vitro infection due to Coxiella burnetii.

Journal: The Journal of antimicrobial chemotherapy 20081001

Title: Potent inhibition of cicatricial contraction in proliferative vitreoretinal diseases by statins.

Journal: Diabetes 20081001

Title: Suppression of CYP2B induction by alendronate-mediated farnesyl diphosphate synthase inhibition in primary cultured rat hepatocytes.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20081001

Title: Prenatal exposure to HMG-CoA reductase inhibitors: effects on fetal and neonatal outcomes.

Journal: Reproductive toxicology (Elmsford, N.Y.) 20081001

Title: Effect of albumin on the biliary clearance of compounds in sandwich-cultured rat hepatocytes.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20081001

Title: Statins limit Rickettsia conorii infection in cells.

Journal: International journal of antimicrobial agents 20081001

Title: Ptosis, diplopia and statins: an association?

Journal: European journal of neurology 20081001

Title: The relationship between the effect of pravastatin and risk factors for coronary heart disease in Japanese patients with hypercholesterolemia.

Journal: Circulation journal : official journal of the Japanese Circulation Society 20081001

Title: Practical risk prediction tools for coronary heart disease in mild to moderate hypercholesterolemia in Japan: originated from the MEGA study data.

Journal: Circulation journal : official journal of the Japanese Circulation Society 20081001

Title: Polymorphism of the hepatic influx transporter organic anion transporting polypeptide 1B1 is associated with increased cholesterol synthesis rate.

Journal: Pharmacogenetics and genomics 20081001

Title: Neutrophil activation by the tissue factor/Factor VIIa/PAR2 axis mediates fetal death in a mouse model of antiphospholipid syndrome.

Journal: The Journal of clinical investigation 20081001

Title: Statins: under investigation for increasing bone mineral density and augmenting fracture healing.

Journal: Expert opinion on investigational drugs 20081001

Title: A combination of proteasome inhibitors and antibiotics prevents lethality in a septic shock model.

Journal: Innate immunity 20081001

Title: A gift from nature: the birth of the statins.

Journal: Nature medicine 20081001

Title: Comparison of the effect of lipophilic and hydrophilic statins on serum adiponectin levels in patients with mild hypertension and dyslipidemia: Kinki Adiponectin Interventional (KAI) Study.

Journal: Clinical and experimental hypertension (New York, N.Y. : 1993) 20081001

Title: Atorvastatin therapy is associated with reduced levels of N-terminal prohormone brain natriuretic peptide and improved cardiac function in patients with heart failure.

Journal: Clinical cardiology 20081001

Title: Influence of pitavastatin on glucose tolerance in patients with type 2 diabetes mellitus.

Journal: Journal of atherosclerosis and thrombosis 20081001

Title: Inhibition of cardiac remodeling by pravastatin is associated with amelioration of endoplasmic reticulum stress.

Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20081001

Title: Excess coronary artery disease risk in South Asian immigrants: can dysfunctional high-density lipoprotein explain increased risk?

Journal: Vascular health and risk management 20081001

Title: Update on the clinical utility of fenofibrate in mixed dyslipidemias: mechanisms of action and rational prescribing.

Journal: Vascular health and risk management 20081001

Title: Baseline low-density lipoprotein cholesterol is an important predictor of the benefit of intensive lipid-lowering therapy: a PROVE IT-TIMI 22 (Pravastatin or Atorvastatin Evaluation and Infection Therapy-Thrombolysis In Myocardial Infarction 22) analysis.

Journal: Journal of the American College of Cardiology 20080909

Title: Phytosterols dissolved in diacylglycerol oil reinforce the cholesterol-lowering effect of low-dose pravastatin treatment.

Journal: Nutrition, metabolism, and cardiovascular diseases : NMCD 20080901

Title: Impact on mortality following first acute myocardial infarction of distance between home and hospital: cohort study.

Journal: Heart (British Cardiac Society) 20080901

Title: Genetic variation at the LDL receptor and HMG-CoA reductase gene loci, lipid levels, statin response, and cardiovascular disease incidence in PROSPER.

Journal: Atherosclerosis 20080901

Title: Genetic variation at the PCSK9 locus moderately lowers low-density lipoprotein cholesterol levels, but does not significantly lower vascular disease risk in an elderly population.

Journal: Atherosclerosis 20080901

Title: Statin therapy increases carotid plaque echogenicity in hypercholesterolemic patients.

Journal: Ultrasound in medicine & biology 20080901

Title: Effects of atorvastatin and pravastatin on glucose tolerance, adipokine levels and inflammatory markers in hypercholesterolaemic patients.

Journal: Clinical and experimental pharmacology & physiology 20080901

Title: Determination of sodium cromoglycate in human plasma by liquid chromatography with tandem mass.

Journal: Biomedical chromatography : BMC 20080901

Title: Pravastatin improves renal ischemia-reperfusion injury by inhibiting the mevalonate pathway.

Journal: Kidney international 20080901

Title: Mesodermal fate decisions of a stem cell: the Wnt switch.

Journal: Cellular and molecular life sciences : CMLS 20080901

Title: Combination regimen with statins and NSAIDs: a promising strategy for cancer chemoprevention.

Journal: International journal of cancer 20080901

Title: Utility of a novel Oatp1b2 knockout mouse model for evaluating the role of Oatp1b2 in the hepatic uptake of model compounds.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20080901

Title: In vitro biliary clearance of angiotensin II receptor blockers and 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors in sandwich-cultured rat hepatocytes: comparison with in vivo biliary clearance.

Journal: The Journal of pharmacology and experimental therapeutics 20080901

Title: Identification of the specific sequence recognized by Penicillium citrinum MlcR, a GAL4-type transcriptional activator of ML-236B (compactin) biosynthetic genes.

Journal: Fungal genetics and biology : FG & B 20080901

Title: Progression of kidney disease in moderately hypercholesterolemic, hypertensive patients randomized to pravastatin versus usual care: a report from the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT).

Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 20080901

Title: Investigating the potential neuroprotective effects of statins on DNA damage in mouse striatum.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20080901

Title: Statins inhibit toll-like receptor 4-mediated lipopolysaccharide signaling and cytokine expression.

Journal: Pharmacogenetics and genomics 20080901

Title: Multiple effects of HMG-CoA reductase inhibitors (statins) besides their lipid-lowering function.

Journal: Kidney international 20080901

Title: Outcomes of patients with acute coronary syndrome and previous coronary artery bypass grafting (from the Pravastatin or Atorvastatin Evaluation and Infection Therapy [PROVE IT-TIMI 22] and the Aggrastat to Zocor [A to Z] trials).

Journal: The American journal of cardiology 20080901

Title: Statins for slowing kidney disease progression: an as yet unproven indication.

Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 20080901

Title: Pharmacogenomic importance of pravastatin.

Journal: Pharmacogenomics 20080901

Title: Effect of simvastatin on steroid-induced osteonecrosis evidenced by the serum lipid level and hepatic cytochrome P4503A in a rabbit model.

Journal: Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association 20080901

Title: HIV infection in the elderly.

Journal: Clinical interventions in aging 20080901

Title: Can HMG Co-A reductase inhibitors ('statins') slow the progression of age-related macular degeneration? The age-related maculopathy statin study (ARMSS).

Journal: Clinical interventions in aging 20080901

Title: [Impact of statins on clopidogrel platelet inhibition in patients with acute coronary syndrome or stable angina].

Journal: Zhonghua xin xue guan bing za zhi 20080901

Title: Effects of pravastatin on obesity, diabetes, and adiponectin in diet-induced obese mice.

Journal: Obesity (Silver Spring, Md.) 20080901

Title: Mevinolin, citrinin and pigments of adlay angkak fermented by Monascus sp.

Journal: International journal of food microbiology 20080815

Title: Increased adiponectin synthesis in the visceral adipose tissue in men with coronary artery disease treated with pravastatin: a role of the attenuation of oxidative stress.

Journal: Atherosclerosis 20080801

Title: Correlates of LDL-cholesterol goal attainment in patients under lipid lowering therapy.

Journal: Atherosclerosis 20080801

Title: Association between global leukocyte DNA methylation, renal function, carotid intima-media thickness and plasma homocysteine in patients with stage 2-4 chronic kidney disease.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20080801

Title: Effect of APOE genotype on lipid levels in patients with coronary heart disease during a 3-week inpatient rehabilitation program.

Journal: Clinical pharmacology and therapeutics 20080801

Title: Targeted disruption of murine organic anion-transporting polypeptide 1b2 (Oatp1b2/Slco1b2) significantly alters disposition of prototypical drug substrates pravastatin and rifampin.

Journal: Molecular pharmacology 20080801

Title: Colesevelam HCl improves glycemic control and reduces LDL cholesterol in patients with inadequately controlled type 2 diabetes on sulfonylurea-based therapy.

Journal: Diabetes care 20080801

Title: Role of the murine organic anion-transporting polypeptide 1b2 (Oatp1b2) in drug disposition and hepatotoxicity.

Journal: Molecular pharmacology 20080801

Title: Involvement of organic anion transporting polypeptides in the toxicity of hydrophilic pravastatin and lipophilic fluvastatin in rat skeletal myofibres.

Journal: British journal of pharmacology 20080801

Title: Lymphotoxin-alpha C804A polymorphism is a risk factor for stroke. The PROSPER study.

Journal: Experimental gerontology 20080801

Title: Dose-dependent effect of rosuvastatin on VLDL-apolipoprotein C-III kinetics in the metabolic syndrome.

Journal: Diabetes care 20080801

Title: Effects of statins on high-density lipoproteins: a potential contribution to cardiovascular benefit.

Journal: Cardiovascular drugs and therapy 20080801

Title: Subclinical atherosclerosis: what it is, what it means and what we can do about it.

Journal: International journal of clinical practice 20080801

Title: Impact of a combined treatment of angiotensin II type 1 receptor blockade and 3-hydroxy-3-methyl-glutaryl-CoA-reductase inhibition on secretory phospholipase A2-type IIA and low density lipoprotein oxidation in patients with coronary artery disease.

Journal: European heart journal 20080801

Title: Differential mechanisms of angiotensin II and PDGF-BB on migration and proliferation of coronary artery smooth muscle cells.

Journal: Journal of molecular and cellular cardiology 20080801

Title: LDL-C reductions and goal attainment among naive statin users in the Netherlands: real life results.

Journal: Current medical research and opinion 20080801

Title: Hyperglycemia induces apoptosis of human pancreatic islet endothelial cells: effects of pravastatin on the Akt survival pathway.

Journal: The American journal of pathology 20080801

Title: Pravastatin-induced colitis.

Journal: European journal of gastroenterology & hepatology 20080801

Title: Interactions between the single nucleotide polymorphisms in the homocysteine pathway (MTHFR 677C>T, MTHFR 1298 A>C, and CBSins) and the efficacy of HMG-CoA reductase inhibitors in preventing cardiovascular disease in high-risk patients of hypertension: the GenHAT study.

Journal: Pharmacogenetics and genomics 20080801

Title: Pravastatin reduces the risk for cardiovascular disease in Japanese hypercholesterolemic patients with impaired fasting glucose or diabetes: diabetes subanalysis of the Management of Elevated Cholesterol in the Primary Prevention Group of Adult Japanese (MEGA) Study.

Journal: Atherosclerosis 20080801

Title: Lipophilicity and cardiovascular outcome in patients with CHF.

Journal: American heart journal 20080801

Title: Determination of RBC membrane and serum lipid composition in Trinidadian type II diabetics with and without nephropathy.

Journal: Vascular health and risk management 20080801

Title: The Relationship Between HIV Infection and Cardiovascular Disease.

Journal: Current cardiology reviews 20080801

Title: Pharmacological prevention of peri-, and post-procedural myocardial injury in percutaneous coronary intervention.

Journal: Current cardiology reviews 20080801

Title: Role of pharmacogenomics in drug discovery and development.

Journal: Indian journal of pharmacology 20080801

Title: Contribution of the mevalonate and methylerythritol phosphate pathways to the biosynthesis of dolichols in plants.

Journal: The Journal of biological chemistry 20080725

Title: LC and LC-MS methods for the investigation of polypills for the treatment of cardiovascular diseases. Part 1. Separation of active components and classification of their interaction/degradation products.

Journal: Journal of pharmaceutical and biomedical analysis 20080715

Title: Magnesium cation effect on passive diffusion of statin molecules: molecular chromatography approach.

Journal: Journal of pharmaceutical and biomedical analysis 20080715

Title: Re: The association between statins and cancer incidence in a veterans population.

Journal: Journal of the National Cancer Institute 20080702

Title: Gender-specific regulation of pancreatic islet blood flow, insulin levels and glycaemia in spontaneously diabetic Goto-Kakizaki rats.

Journal: Clinical science (London, England : 1979) 20080701

Title: Efficacy and safety of disodium ascorbyl phytostanol phosphates in men with moderate dyslipidemia.

Journal: European journal of clinical pharmacology 20080701

Title: Statin treatment of adult human glial progenitors induces PPAR gamma-mediated oligodendrocytic differentiation.

Journal: Glia 20080701

Title: Effect of plasma protein binding on in vitro-in vivo correlation of biliary excretion of drugs evaluated by sandwich-cultured rat hepatocytes.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20080701

Title: On-line extraction coupled with liquid chromatography tandem mass spectrometry for quantitation of pravastatin and its metabolite in human serum.

Journal: Biomedical chromatography : BMC 20080701

Title: Interactions between cell death induced by statins and 7-ketocholesterol in rabbit aorta smooth muscle cells.

Journal: British journal of pharmacology 20080701

Title: Pravastatin attenuates carboplatin-induced cardiotoxicity via inhibition of oxidative stress associated apoptosis.

Journal: Apoptosis : an international journal on programmed cell death 20080701

Title: The occurrence of pharmaceuticals, personal care products, endocrine disruptors and illicit drugs in surface water in South Wales, UK.

Journal: Water research 20080701

Title: Relationship between biomarkers of oxidized low-density lipoprotein, statin therapy, quantitative coronary angiography, and atheroma: volume observations from the REVERSAL (Reversal of Atherosclerosis with Aggressive Lipid Lowering) study.

Journal: Journal of the American College of Cardiology 20080701

Title: Combined treatment with statins and aminobisphosphonates extends longevity in a mouse model of human premature aging.

Journal: Nature medicine 20080701

Title: Treatment of coronary spastic angina with a statin in addition to a calcium channel blocker: a pilot study.

Journal: Journal of cardiovascular pharmacology 20080701

Title: Rejuvenating premature aging.

Journal: Nature medicine 20080701

Title: Lipid management: considerations in acute coronary syndrome.

Journal: Current cardiology reports 20080701

Title: Pravastatin increases the expression of the tissue inhibitor of matrix metalloproteinase-1 and the oncogene Bax in human aortic abdominal aneurysms.

Journal: Canadian journal of physiology and pharmacology 20080701

Title: Cost-effectiveness analysis of rosuvastatin versus atorvastatin, simvastatin, and pravastatin from a Canadian health system perspective.

Journal: Clinical therapeutics 20080701

Title: Atorvastatin-induced changes in plasma coenzyme q10 and brain natriuretic peptide in patients with coronary artery disease.

Journal: International heart journal 20080701

Title: Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).

Journal: Journal of medicinal chemistry 20080612

Title: Evidence for AMPK-dependent regulation of exocytosis of lipoproteins in a model liver cell line.

Journal: Experimental cell research 20080610

Title: Can metabolic syndrome usefully predict cardiovascular disease and diabetes? Outcome data from two prospective studies.

Journal: Lancet (London, England) 20080607

Title: Neuroprotection by pravastatin in acute ischemic stroke in rats.

Journal: Brain research reviews 20080601

Title: Effect of genipin on the biliary excretion of cholephilic compounds in rats.

Journal: Hepatology research : the official journal of the Japan Society of Hepatology 20080601

Title: Statins reduce neuronal alpha-synuclein aggregation in in vitro models of Parkinson's disease.

Journal: Journal of neurochemistry 20080601

Title: Interaction of oral antidiabetic drugs with hepatic uptake transporters: focus on organic anion transporting polypeptides and organic cation transporter 1.

Journal: Diabetes 20080601

Title: Association of circulating leukocyte count with coronary atherosclerosis regression after pravastatin treatment.

Journal: Atherosclerosis 20080601

Title: Statins restore ischemic limb blood flow in diabetic microangiopathy via eNOS/NO upregulation but not via PDGF-BB expression.

Journal: American journal of physiology. Heart and circulatory physiology 20080601

Title: The comparative effectiveness of rosuvastatin vs. other statins in patients with an increased risk of failure to reach NCEP ATP III goal.

Journal: International journal of clinical practice 20080601

Title: Statins (HMG-coenzyme A reductase inhibitors)-biomimetic membrane binding mechanism investigated by molecular chromatography.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20080601

Title: Efficacy of lipid-lowering medications in patients treated with clozapine: a naturalistic study.

Journal: Journal of clinical psychopharmacology 20080601

Title: Atherogenic lipoprotein particle size and concentrations and the effect of pravastatin in children with familial hypercholesterolemia.

Journal: The Journal of pediatrics 20080601

Title: The relation between extent of coronary artery disease measured by quantitative coronary angiography and changes in lipid profile: insights from trials of atherosclerosis regression.

Journal: The Journal of invasive cardiology 20080601

Title: Overview of the proton-coupled MCT (SLC16A) family of transporters: characterization, function and role in the transport of the drug of abuse gamma-hydroxybutyric acid.

Journal: The AAPS journal 20080601

Title: Mortality in COPD: inevitable or preventable? Insights from the cardiovascular arena.

Journal: COPD 20080601

Title: Pravastatin: an evidence-based statin?

Journal: Expert opinion on drug metabolism & toxicology 20080601

Title: Pravastatin immunomodulates IL-6 and C-reactive protein, but not IL-1 and TNF-alpha, in cardio-pulmonary bypass.

Journal: European cytokine network 20080601

Title: Atorvastatin and cardiovascular risk in the elderly--patient considerations.

Journal: Clinical interventions in aging 20080601

Title: New evidences for C-reactive protein (CRP) deposits in the arterial intima as a cardiovascular risk factor.

Journal: Clinical interventions in aging 20080601

Title: Epidemiology and economics of statin use.

Journal: Irish medical journal 20080601

Title: [Pleiotropic effects of statins].

Journal: Revista medica de Chile 20080601

Title: Relative safety profiles of high dose statin regimens.

Journal: Vascular health and risk management 20080601

Title: Early vascular aging (EVA): consequences and prevention.

Journal: Vascular health and risk management 20080601

Title: The secretory phospholipase A2 group IIA: a missing link between inflammation, activated renin-angiotensin system, and atherogenesis?

Journal: Vascular health and risk management 20080601

Title: Cardiovascular co-morbidity in rheumatic diseases.

Journal: Vascular health and risk management 20080601

Title: Fixed combinations in the management of hypertension: patient perspectives and rationale for development and utility of the olmesartan-amlodipine combination.

Journal: Vascular health and risk management 20080601

Title: [Metabolic side effects of antiretroviral therapy].

Journal: Nederlands tijdschrift voor geneeskunde 20080531

Title: Repression of BK virus infection of human renal proximal tubular epithelial cells by pravastatin.

Journal: Transplantation 20080515

Title: Estimation of treatment effect adjusting for treatment changes using the intensity score method: application to a large primary prevention study for coronary events (MEGA study).

Journal: Statistics in medicine 20080510

Title: Polymorphisms of the HNF1A gene encoding hepatocyte nuclear factor-1 alpha are associated with C-reactive protein.

Journal: American journal of human genetics 20080509

Title: (3R,5S,E)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(methyl(1-methyl-1h-1,2,4-triazol-5-yl)amino)pyrimidin-5-yl)-3,5-dihydroxyhept-6-enoic acid (BMS-644950): a rationally designed orally efficacious 3-hydroxy-3-methylglutaryl coenzyme-a reductase inhibitor with reduced myotoxicity potential.

Journal: Journal of medicinal chemistry 20080508

Title: Monitoring cholesterol levels: measurement error or true change?

Journal: Annals of internal medicine 20080506

Title: An automated method for the simultaneous determination of pravastatin, 3-hydroxy isomeric metabolite, pravalactone and fenofibric acid in human plasma by sensitive liquid chromatography combined with diode array and tandem mass spectrometry detection.

Journal: Journal of chromatography. A 20080502

Title: Effects of statins on adipose tissue inflammation: their inhibitory effect on MyD88-independent IRF3/IFN-beta pathway in macrophages.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20080501

Title: Treatment with an apolipoprotein A-1 mimetic peptide in combination with pravastatin inhibits collagen-induced arthritis.

Journal: Clinical immunology (Orlando, Fla.) 20080501

Title: Effective management of hypertension with dihydropyridine calcium channel blocker-based combination therapy in patients at high cardiovascular risk.

Journal: International journal of clinical practice 20080501

Title: Atorvastatin monotherapy vs. combination therapy in the management of patients with combined hyperlipidemia.

Journal: European journal of internal medicine 20080501

Title: Drug-induced liver injury in 2007.

Journal: Current opinion in gastroenterology 20080501

Title: The effect of SLCO1B1*15 on the disposition of pravastatin and pitavastatin is substrate dependent: the contribution of transporting activity changes by SLCO1B1*15.

Journal: Pharmacogenetics and genomics 20080501

Title: High-dose atorvastatin does not negatively influence clinical outcomes among clopidogrel treated acute coronary syndrome patients--a Pravastatin or Atorvastatin Evaluation and Infection Therapy-Thrombolysis in Myocardial Infarction 22 (PROVE IT-TIMI 22) analysis.

Journal: American heart journal 20080501

Title: Effects of atorvastatin and pravastatin on signal transduction related to glucose uptake in 3T3L1 adipocytes.

Journal: Journal of pharmacological sciences 20080501

Title: Communicating the results of clinical research to participants: attitudes, practices, and future directions.

Journal: PLoS medicine 20080501

Title: Pravastatin as a therapeutic agent for atypical antipsychotic-induced metabolic syndrome in patients with schizophrenia.

Journal: CNS spectrums 20080501

Title: HMG-CoA reductase inhibitors deplete circulating classical and non-classical monocytes following human heart transplantation.

Journal: Transplant immunology 20080501

Title: Pathogenesis and management of lipoatrophy.

Journal: Current HIV/AIDS reports 20080501

Title: Effectiveness of lipid-lowering therapy in HIV patients.

Journal: Current opinion in HIV and AIDS 20080501

Title: Cardiovascular disease in systemic lupus erythematosus: the role of traditional and lupus related risk factors.

Journal: Current cardiology reviews 20080501

Title: The influence of pravastatin and atorvastatin on markers of oxidative stress in hypercholesterolemic humans.

Journal: Journal of the American College of Cardiology 20080429

Title: Statin induced myotoxicity: the lactone forms are more potent than the acid forms in human skeletal muscle cells in vitro.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20080423

Title: Association between risk of myopathy and cholesterol-lowering effect: a comparison of all statins.

Journal: Life sciences 20080423

Title: Reduction in blood pressure with statins: results from the UCSD Statin Study, a randomized trial.

Journal: Archives of internal medicine 20080414

Title: Dual mechanisms for the fibrate-mediated repression of proprotein convertase subtilisin/kexin type 9.

Journal: The Journal of biological chemistry 20080411

Title: Granulocytic sarcoma with massive scalp involvement.

Journal: American journal of hematology 20080401

Title: The effect of HMG-CoA reductase inhibitors on naturally occurring CD4+CD25+ T cells.

Journal: Atherosclerosis 20080401

Title: Early changes in arterial structure and function following statin initiation: quantification by magnetic resonance imaging.

Journal: Atherosclerosis 20080401

Title: Regulation of the PTEN promoter by statins and SREBP.

Journal: Human molecular genetics 20080401

Title: Intracellular cholesterol modifies the ERAD of glucocerebrosidase in Gaucher disease patients.

Journal: Molecular genetics and metabolism 20080401

Title: Early Improvements in insulin sensitivity and inflammatory markers are induced by pravastatin in nondiabetic subjects with hypercholesterolemia.

Journal: Clinica chimica acta; international journal of clinical chemistry 20080401

Title: 'Real-life' reduction in cholesterol with statins, 1993 to 2002.

Journal: British journal of clinical pharmacology 20080401

Title: Statin treatment in hypercholesterolemic pregnant mice reduces cardiovascular risk factors in their offspring.

Journal: Hypertension (Dallas, Tex. : 1979) 20080401

Title: The value of N-terminal fragment of brain natriuretic peptide and tissue inhibitor of metalloproteinase-1 levels as predictors of cardiovascular outcome in the LIPID study.

Journal: European heart journal 20080401

Title: Genetic variation in the interleukin-1 beta-converting enzyme associates with cognitive function. The PROSPER study.

Journal: Brain : a journal of neurology 20080401

Title: Initiating statins in the elderly: the evolving challenge.

Journal: Current opinion in endocrinology, diabetes, and obesity 20080401

Title: Apolipoprotein E genotypes are associated with lipid-lowering responses to statin treatment in diabetes: a Go-DARTS study.

Journal: Pharmacogenetics and genomics 20080401

Title: Atorvastatin induces apoptosis by a caspase-9-dependent pathway: an in vitro study on activated rat hepatic stellate cells.

Journal: Liver international : official journal of the International Association for the Study of the Liver 20080401

Title: Lipid levels and low-density lipoprotein cholesterol goal attainment in diabetic patients: rosuvastatin compared with other statins in usual care.

Journal: Expert opinion on pharmacotherapy 20080401

Title: Rationale and design of a study to examine lower targets for low-density lipoprotein-cholesterol and blood pressure in coronary artery disease patients.

Journal: Circulation journal : official journal of the Japanese Circulation Society 20080401

Title: Primary prevention with pravastatin for 5 years continued to prevent coronary events in the next 10 years.

Journal: Evidence-based nursing 20080401

Title: Statins inhibit proliferation and induce apoptosis in Barrett's esophageal adenocarcinoma cells.

Journal: The American journal of gastroenterology 20080401

Title: Statins in esophageal cancer cell lines: promising lead?

Journal: The American journal of gastroenterology 20080401

Title: [Use of statins in children].

Journal: Anales de pediatria (Barcelona, Spain : 2003) 20080401

Title: Inflammatory markers in nondiabetic and diabetic rat retinas exposed to ischemia followed by reperfusion.

Journal: Retina (Philadelphia, Pa.) 20080401

Title: Effects of rosuvastatin and pitavastatin on ischemia-induced myocardial stunning in dogs.

Journal: Journal of pharmacological sciences 20080401

Title: Can cheap generic statins achieve national cholesterol lowering targets?

Journal: Journal of health services research & policy 20080401

Title: Adjunctive interventions in myocardial infarction: the role of statin therapy.

Journal: Current atherosclerosis reports 20080401

Title: Pharmacological topics of bone metabolism: antiresorptive microbial compounds that inhibit osteoclast differentiation, function, and survival.

Journal: Journal of pharmacological sciences 20080401

Title: Do statins prevent or promote cancer?

Journal: Current oncology (Toronto, Ont.) 20080401

Title: Combination therapy in cholesterol reduction: focus on ezetimibe and statins.

Journal: Vascular health and risk management 20080401

Title: Orlistat in the prevention of diabetes in the obese patient.

Journal: Vascular health and risk management 20080401

Title: Clinical efficacy and safety of statins in managing cardiovascular risk.

Journal: Vascular health and risk management 20080401

Title: Vascular risk factors, cognitive decline, and dementia.

Journal: Vascular health and risk management 20080401

Title: Preferred drug lists: potential impact on healthcare economics.

Journal: Vascular health and risk management 20080401

Title: Monascus purpureus Went rice in nephrotic hyperlipidemia.

Journal: Indian journal of nephrology 20080401

Title: A case of vasospastic angina showing resolution of coronary vasospasm in acetylcholine provocation test corresponding to regression of coronary atherosclerosis.

Journal: International journal of cardiology 20080328

Title: Activation of the farnesoid X receptor represses PCSK9 expression in human hepatocytes.

Journal: FEBS letters 20080319

Title: Differences in antitumor effects of various statins on human pancreatic cancer.

Journal: International journal of cancer 20080315

Title: Tendinous disorders attributed to statins: a study on ninety-six spontaneous reports in the period 1990-2005 and review of the literature.

Journal: Arthritis and rheumatism 20080315

Title: Hydrophobic statins induce autophagy in cultured human rhabdomyosarcoma cells.

Journal: Biochemical and biophysical research communications 20080307

Title: Association between ADAMTS1 matrix metalloproteinase gene variation, coronary heart disease, and benefit of statin therapy.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20080301

Title: Estimating the extent of reporting to FDA: a case study of statin-associated rhabdomyolysis.

Journal: Pharmacoepidemiology and drug safety 20080301

Title: The Food and Drug Administration and over-the-counter statins: an opportunity lost?

Journal: Journal of clinical hypertension (Greenwich, Conn.) 20080301

Title: Inhibition of macrophage phagocytotic activity by a receptor-targeted polymer vesicle-based drug delivery formulation of pravastatin.

Journal: Journal of cardiovascular pharmacology 20080301

Title: Flexible initial dosing of atorvastatin based upon initial low-density lipoprotein cholesterol levels in type 2 diabetic patients.

Journal: The Korean journal of internal medicine 20080301

Title: Statins impair antitumor effects of rituximab by inducing conformational changes of CD20.

Journal: PLoS medicine 20080301

Title: Metabolic myopathies discovered during investigations of statin myopathy.

Journal: The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 20080301

Title: [Effects of pravastatin in prevention of diabetes and mechanism thereof: experiment with non-obese diabetic mice].

Journal: Zhonghua yi xue za zhi 20080226

Title: Impact of triglyceride levels beyond low-density lipoprotein cholesterol after acute coronary syndrome in the PROVE IT-TIMI 22 trial.

Journal: Journal of the American College of Cardiology 20080219

Title: Reversal of chemoresistance and enhancement of apoptosis by statins through down-regulation of the NF-kappaB pathway.

Journal: Biochemical pharmacology 20080215

Title: Cardiovascular health in New Zealand: areas of concern and targets for improvement in 2008 and beyond.

Journal: The New Zealand medical journal 20080215

Title: Differences in cardiovascular mortality between Australia and New Zealand according to socioeconomic status: findings from the Long-Term Intervention with Pravastatin in Ischaemic Disease (LIPID) Study.

Journal: The New Zealand medical journal 20080215

Title: Usefulness of C-reactive protein and interleukin-6 as predictors of outcomes in patients with chronic obstructive pulmonary disease receiving pravastatin.

Journal: The American journal of cardiology 20080215

Title: Determination of two HMG-CoA reductase inhibitors, pravastatin and pitavastatin, in plasma samples using liquid chromatography-tandem mass spectrometry for pharmaceutical study.

Journal: Biomedical chromatography : BMC 20080201

Title: The Guinea pig as a preclinical model for demonstrating the efficacy and safety of statins.

Journal: The Journal of pharmacology and experimental therapeutics 20080201

Title: Non-synonymous polymorphisms in the human SLCO1B1 gene: an in vitro analysis of SNP c.1929A>C.

Journal: Molecular genetics and genomics : MGG 20080201

Title: Phospholipid chlorohydrin induces leukocyte adhesion to ApoE-/- mouse arteries via upregulation of P-selectin.

Journal: Free radical biology & medicine 20080201

Title: Chronic kidney disease mineral and bone disorder in children.

Journal: Pediatric nephrology (Berlin, Germany) 20080201

Title: Use of recommended medications after myocardial infarction in Austria.

Journal: European journal of epidemiology 20080201

Title: Hepatoselectivity of statins: design and synthesis of 4-sulfamoyl pyrroles as HMG-CoA reductase inhibitors.

Journal: Bioorganic & medicinal chemistry letters 20080201

Title: Effect of statin dose on incidence of atrial fibrillation: data from the Pravastatin or Atorvastatin Evaluation and Infection Therapy-Thrombolysis in Myocardial Infarction 22 (PROVE IT-TIMI 22) and Aggrastat to Zocor (A to Z) trials.

Journal: American heart journal 20080201

Title: Class effects of statins in elderly patients with congestive heart failure: a population-based analysis.

Journal: American heart journal 20080201

Title: Pharmacogenetics: data, concepts and tools to improve drug discovery and drug treatment.

Journal: European journal of clinical pharmacology 20080201

Title: Direct effect of statins on homocysteine-induced endothelial adhesiveness: potential impact to human atherosclerosis.

Journal: European journal of clinical investigation 20080201

Title: Statins induce lethal effects in acute myeloblastic leukemia [corrected] cells within 72 hours.

Journal: Leukemia & lymphoma 20080201

Title: Usefulness of statin pretreatment to prevent contrast-induced nephropathy and to improve long-term outcome in patients undergoing percutaneous coronary intervention.

Journal: The American journal of cardiology 20080201

Title: Impact of systemic hypertension on the cardiovascular benefits of statin therapy--a meta-analysis.

Journal: The American journal of cardiology 20080201

Title: The mechanism of carrier-mediated transport of folates in BeWo cells: the involvement of heme carrier protein 1 in placental folate transport.

Journal: Bioscience, biotechnology, and biochemistry 20080201

Title: What is the evidence in favor of low-dose statin therapy in 2008?

Journal: Current atherosclerosis reports 20080201

Title: Update on the use of fibrates: focus on bezafibrate.

Journal: Vascular health and risk management 20080201

Title: Perioperative use of statins in noncardiac surgery.

Journal: Vascular health and risk management 20080201

Title: High density lipoprotein cholesterol: an evolving target of therapy in the management of cardiovascular disease.

Journal: Vascular health and risk management 20080201

Title: Usefulness of pravastatin in primary prevention of cardiovascular events in women: analysis of the Management of Elevated Cholesterol in the Primary Prevention Group of Adult Japanese (MEGA study).

Journal: Circulation 20080129

Title: Association of the Trp719Arg polymorphism in kinesin-like protein 6 with myocardial infarction and coronary heart disease in 2 prospective trials: the CARE and WOSCOPS trials.

Journal: Journal of the American College of Cardiology 20080129

Title: Polymorphism in KIF6 gene and benefit from statins after acute coronary syndromes: results from the PROVE IT-TIMI 22 study.

Journal: Journal of the American College of Cardiology 20080129

Title: The association between statins and cancer incidence in a veterans population.

Journal: Journal of the National Cancer Institute 20080116

Title: Synergistic induction of apoptosis by HMG-CoA reductase inhibitor and histone deacetylases inhibitor in HeLa cells.

Journal: Biochemical and biophysical research communications 20080111

Title: Substituted pyrazoles as hepatoselective HMG-CoA reductase inhibitors: discovery of (3R,5R)-7-[2-(4-fluoro-phenyl)-4-isopropyl-5-(4-methyl-benzylcarbamoyl)-2H-pyrazol-3-yl]-3,5-dihydroxyheptanoic acid (PF-3052334) as a candidate for the treatment of hypercholesterolemia.

Journal: Journal of medicinal chemistry 20080110

Title: Long-term follow-up of the West of Scotland Coronary Prevention Study.

Journal: The New England journal of medicine 20080110

Title: Long-term follow-up of the West of Scotland Coronary Prevention Study.

Journal: The New England journal of medicine 20080110

Title: Long-term follow-up of the West of Scotland Coronary Prevention Study.

Journal: The New England journal of medicine 20080110

Title: [Influence of pravastatin on blood lipids and serum high sensitive C-reactive protein in patients undergoing conventional coronary artery bypass grafting under on-pump: a clinical study of 81 cases].

Journal: Zhonghua yi xue za zhi 20080108

Title: Hydroxymethylglutaryl--CoA reductase inhibitor inhibits induction of nitric oxide synthase in 3T3--L1 preadipocytes.

Journal: Life sciences 20080102

Title: Long-term effects of pravastatin and fosinopril on peripheral endothelial function in albuminuric subjects.

Journal: Atherosclerosis 20080101

Title: Effect of pravastatin on the development of diabetes and adiponectin production.

Journal: Atherosclerosis 20080101

Title: Estimation of the marginal survival time in the presence of dependent competing risks using inverse probability of censoring weighted (IPCW) methods.

Journal: Pharmaceutical statistics 20080101

Title: Hydrophobic but not hydrophilic statins enhance phagocytosis and decrease apoptosis of human peripheral blood cells in vitro.

Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20080101

Title: The significance of compliance and persistence in the treatment of diabetes, hypertension and dyslipidaemia: a review.

Journal: International journal of clinical practice 20080101

Title: Myeloid-related protein 8/14 and the risk of cardiovascular death or myocardial infarction after an acute coronary syndrome in the Pravastatin or Atorvastatin Evaluation and Infection Therapy: Thrombolysis in Myocardial Infarction (PROVE IT-TIMI 22) trial.

Journal: American heart journal 20080101

Title: Protection of pancreatic beta-cells: is it feasible?

Journal: Nutrition, metabolism, and cardiovascular diseases : NMCD 20080101

Title: Effect of early use of low-dose pravastatin on major adverse cardiac events in patients with acute myocardial infarction: the OACIS-LIPID Study.

Journal: Circulation journal : official journal of the Japanese Circulation Society 20080101

Title: Effects of beta-hydroxy-beta-methylbutyrate (HMB) on exercise performance and body composition across varying levels of age, sex, and training experience: A review.

Journal: Nutrition & metabolism 20080101

Title: Statins for secondary prevention in elderly patients: a hierarchical bayesian meta-analysis.

Journal: Journal of the American College of Cardiology 20080101

Title: Contribution of multidrug resistance-associated protein 2 to secretory intestinal transport of organic anions.

Journal: Biological & pharmaceutical bulletin 20080101

Title: [Effect of electro-acupuncture at Fenglong (GV 16) on nitric oxide and endothelin in rats with hyperlipidemia].

Journal: Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20080101

Title: Lowering LDL-C for optimal protection in high-risk patients.

Journal: The American journal of managed care 20080101

Title: The 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors, simvastatin, lovastatin and mevastatin inhibit proliferation and invasion of melanoma cells.

Journal: BMC cancer 20080101

Title: Pravastatin attenuates left ventricular remodeling and diastolic dysfunction in angiotensin II-induced hypertensive mice.

Journal: Journal of cardiovascular pharmacology 20080101

Title: Impact of cytochrome P450 3A4-metabolized statins on the antiplatelet effect of a 600-mg loading dose clopidogrel and on clinical outcome in patients undergoing elective coronary stent placement.

Journal: Thrombosis and haemostasis 20080101

Title: Incidence of adverse events with HMG-CoA reductase inhibitors in liver transplant patients.

Journal: Clinical transplantation 20080101

Title: Inflammation, carotid intima-media thickness and atherosclerosis in rheumatoid arthritis.

Journal: Arthritis research & therapy 20080101

Title: Recombinant gas vesicles from Halobacterium sp. displaying SIV peptides demonstrate biotechnology potential as a pathogen peptide delivery vehicle.

Journal: BMC biotechnology 20080101

Title: [Effects of electroacupuncture at 'Fenglong' (ST 40) on NO, ET and CGRP levels in the rat with hyperlipidemia].

Journal: Zhongguo zhen jiu = Chinese acupuncture & moxibustion 20080101

Title: Should We Use PPAR Agonists to Reduce Cardiovascular Risk?

Journal: PPAR research 20080101

Title: When research seems like clinical care: a qualitative study of the communication of individual cancer genetic research results.

Journal: BMC medical ethics 20080101

Title: The effects of a graduated aerobic exercise programme on cardiovascular disease risk factors in the NHS workplace: a randomised controlled trial.

Journal: Journal of occupational medicine and toxicology (London, England) 20080101

Title: Primary prevention with pravastatin for 5 years continued to prevent coronary events in the following 10 years.

Journal: ACP journal club 20080101

Title: [Classification of Streptomyces strain Z314 and purification of its product pravastatin].

Journal: Wei sheng wu xue bao = Acta microbiologica Sinica 20080101

Title: Does productivity influence priority setting? A case study from the field of CVD prevention.

Journal: Cost effectiveness and resource allocation : C/E 20080101

Title: Patient-centered modular secondary prevention following acute coronary syndrome: a randomized controlled trial.

Journal: Journal of cardiopulmonary rehabilitation and prevention 20080101

Title: The efficacy of pharmacotherapy for decreasing the expansion rate of abdominal aortic aneurysms: a systematic review and meta-analysis.

Journal: PloS one 20080101

Title: The Lipid lowering and Onset of Renal Disease (LORD) Trial: a randomized double blind placebo controlled trial assessing the effect of atorvastatin on the progression of kidney disease.

Journal: BMC nephrology 20080101

Title: The functional consequences of genetic variations in transporter genes encoding human organic anion-transporting polypeptide family members.

Journal: Expert opinion on drug metabolism & toxicology 20080101

Title: Fosamprenavir or atazanavir once daily boosted with ritonavir 100 mg, plus tenofovir/emtricitabine, for the initial treatment of HIV infection: 48-week results of ALERT.

Journal: AIDS research and therapy 20080101

Title: Chinese red yeast rice (Monascus purpureus-fermented rice) promotes bone formation.

Journal: Chinese medicine 20080101

Title: Cost-effectiveness of rosuvastatin in the prevention of ischemic heart disease in Portugal.

Journal: Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research 20080101

Title: PPAR Genomics and Pharmacogenomics: Implications for Cardiovascular Disease.

Journal: PPAR research 20080101

Title: Statin use is associated with fewer periodontal lesions: A retrospective study.

Journal: BMC oral health 20080101

Title: Ezetimibe effectively lowers LDL-cholesterol in cardiac allograft recipients on stable statin therapy.

Journal: Clinical transplantation 20080101

Title: Implementing electronic clinical reminders for lipid management in patients with ischemic heart disease in the veterans health administration: QUERI Series.

Journal: Implementation science : IS 20080101

Title: Fixed-dose combination therapy with statins: strengths, limitations, and clinical and regulatory considerations.

Journal: American journal of cardiovascular drugs : drugs, devices, and other interventions 20080101

Title: Lipid-altering therapy and atrial fibrillation.

Journal: Cardiology in review 20080101

Title: Pharmacokinetic comparison of the potential over-the-counter statins simvastatin, lovastatin, fluvastatin and pravastatin.

Journal: Clinical pharmacokinetics 20080101

Title: Statin induced myopathy and myalgia: time trend analysis and comparison of risk associated with statin class from 1991-2006.

Journal: PloS one 20080101

Title: Diagnostic uncertainty of Takotusbo cardiomyopathy in a woman with cardiovascular risk factors hijacked at gunpoint: a case report.

Journal: Cases journal 20080101

Title: [Rosuvastatin for the treatment of dyslipidemia in HIV-infected patients receiving highly active antiretroviral therapy. Preliminary experience].

Journal: Enfermedades infecciosas y microbiologia clinica 20080101

Title: Trends in total cholesterol screening and in prescribing lipid-lowering drugs in general practice in the period 1994-2003.

Journal: BMC family practice 20080101

Title: Multicenter double blind trial of autologous bone marrow mononuclear cell transplantation through intracoronary injection post acute myocardium infarction - MiHeart/AMI study.

Journal: Trials 20080101

Title: The pleiotropic effects of simvastatin on retinal microvascular endothelium has important implications for ischaemic retinopathies.

Journal: PloS one 20080101

Title: Statin potentiates human platelet eNOS activity without enhancing eNOS mRNA and protein levels.

Journal: Cerebrovascular diseases (Basel, Switzerland) 20080101

Title: Pharmacokinetic interaction between pravastatin and olmesartan in relation to SLCO1B1 polymorphism.

Journal: Journal of human genetics 20080101

Title: Secondary prevention of coronary heart disease in elderly patients following myocardial infarction: are all HMG-CoA reductase inhibitors alike?

Journal: Drugs & aging 20080101

Title: Modelling neurofibromatosis type 1 tibial dysplasia and its treatment with lovastatin.

Journal: BMC medicine 20080101

Title: Clinical drugs that interact with St. John's wort and implication in drug development.

Journal: Current pharmaceutical design 20080101

Title: [Interrelation between the pathways of isoprenoid biosynthesis and carbon source catabolism in anaerobic and facultatively anaerobic bacteria].

Journal: Mikrobiologiia 20080101

Title: Lifelong reduction of LDL-cholesterol related to a common variant in the LDL-receptor gene decreases the risk of coronary artery disease--a Mendelian Randomisation study.

Journal: PloS one 20080101

Title: Treatment of altered body composition in HIV-associated lipodystrophy: comparison of rosiglitazone, pravastatin, and recombinant human growth hormone.

Journal: HIV clinical trials 20080101

Title: Risk factors for cerebral microbleeds in the elderly.

Journal: Cerebrovascular diseases (Basel, Switzerland) 20080101

Title: Chemoembolization combined with pravastatin improves survival in patients with hepatocellular carcinoma.

Journal: Digestion 20080101

Title: Pilot study of an interactive voice response system to improve medication refill compliance.

Journal: BMC medical informatics and decision making 20080101

Title: Dyslipidemia in primary care--prevalence, recognition, treatment and control: data from the German Metabolic and Cardiovascular Risk Project (GEMCAS).

Journal: Cardiovascular diabetology 20080101

Title: Essential fatty acids and their metabolites could function as endogenous HMG-CoA reductase and ACE enzyme inhibitors, anti-arrhythmic, anti-hypertensive, anti-atherosclerotic, anti-inflammatory, cytoprotective, and cardioprotective molecules.

Journal: Lipids in health and disease 20080101

Title: The prince and the pauper. A tale of anticancer targeted agents.

Journal: Molecular cancer 20080101

Title: Low HDL cholesterol, smoking and IL-13 R130Q polymorphism are associated with myocardial infarction in Greek Cypriot males. A pilot study.

Journal: The open cardiovascular medicine journal 20080101

Title: In silico analysis of methyltransferase domains involved in biosynthesis of secondary metabolites.

Journal: BMC bioinformatics 20080101

Title: Net efficacy adjusted for risk (NEAR): a simple procedure for measuring risk:benefit balance.

Journal: PloS one 20080101

Title: Efficacy of statins in familial hypercholesterolaemia: a long term cohort study.

Journal: BMJ (Clinical research ed.) 20080101

Title: Inhibition of cell growth and VEGF expression in ovarian cancer cells by flavonoids.

Journal: Nutrition and cancer 20080101

Title: Hypoalbuminaemia--a marker of cardiovascular disease in patients with chronic kidney disease stages II-IV.

Journal: International journal of medical sciences 20080101

Title: Practical management of dyslipidemia with elevated lipoprotein(a).

Journal: Journal of the American Pharmacists Association : JAPhA 20080101

Title: High speed clinical data retrieval system with event time sequence feature: with 10 years of clinical data of Hamamatsu University Hospital CPOE.

Journal: Methods of information in medicine 20080101

Title: Parametric conditional frailty models for recurrent cardiovascular events in the lipid study.

Journal: Clinical trials (London, England) 20080101

Title: [Effects of pravastatin on myocardial connexin 43, IFN-gamma and IL-10 expressions in a murine model of viral myocarditis induced by Coxsackievirus B3].

Journal: Zhonghua xin xue guan bing za zhi 20080101

Title: Clinical review: Critical care management of spontaneous intracerebral hemorrhage.

Journal: Critical care (London, England) 20080101

Title: Expression of sterol regulatory element-binding transcription factor (SREBF) 2 and SREBF cleavage-activating protein (SCAP) in human atheroma and the association of their allelic variants with sudden cardiac death.

Journal: Thrombosis journal 20080101

Title: Inhibition of HMG CoA reductase reveals an unexpected role for cholesterol during PGC migration in the mouse.

Journal: BMC developmental biology 20080101

Title: Statins Activate Human PPARalpha Promoter and Increase PPARalpha mRNA Expression and Activation in HepG2 Cells.

Journal: PPAR research 20080101

Title: Statin treatment, carotid atherosclerotic plaque macrophage infiltration and circulating inflammatory markers.

Journal: The open cardiovascular medicine journal 20080101

Title: Determination of key intermediates in cholesterol and bile acid biosynthesis by stable isotope dilution mass spectrometry.

Journal: Analytical chemistry insights 20080101

Title: Effect of onion and beet on plasma and liver lipids, platelet aggregation, and erythrocyte Na efflux in simvastatin treated hypercholesterolmic rats.

Journal: Nutrition research and practice 20080101

Title: Pharmacogenomics Bias - Systematic distortion of study results by genetic heterogeneity.

Journal: GMS health technology assessment 20080101

Title: Microbial production and biomedical applications of lovastatin.

Journal: Indian journal of pharmaceutical sciences 20080101

Title: Stability Indicating RP-HPLC Estimation of Atorvastatin Calcium and Amlodipine Besylate in Pharmaceutical Formulations.

Journal: Indian journal of pharmaceutical sciences 20080101

Title: Hypolipidemia: a word of caution.

Journal: The Libyan journal of medicine 20080101

Title: Frequency and predictors of tablet splitting in statin prescriptions: a population-based analysis.

Journal: Open medicine : a peer-reviewed, independent, open-access journal 20080101

Title: Organic anion transporting polypeptide 1B3 (OATP1B3) is overexpressed in colorectal tumors and is a predictor of clinical outcome.

Journal: Clinical and experimental gastroenterology 20080101

Title: Macrophage NADPH oxidase activation, impaired cholesterol fluxes, and increased cholesterol biosynthesis in diabetic mice: a stimulatory role for D-glucose.

Journal: Atherosclerosis 20071201

Title: Rab-small GTPases are involved in fluvastatin and pravastatin-induced vacuolation in rat skeletal myofibers.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20071201

Title: Mechanisms of progression of chronic kidney disease.

Journal: Pediatric nephrology (Berlin, Germany) 20071201

Title: The effects of high dose pravastatin and low dose pravastatin and ezetimibe combination therapy on lipid, glucose metabolism and inflammation.

Journal: Inflammation 20071201

Title: Synergistic antiproliferative effects of gamma-tocotrienol and statin treatment on mammary tumor cells.

Journal: Lipids 20071201

Title: Evidence of artemisinin production from IPP stemming from both the mevalonate and the nonmevalonate pathways.

Journal: Plant cell reports 20071201

Title: Effect of pravastatin on sympathetic reinnervation in postinfarcted rats.

Journal: American journal of physiology. Heart and circulatory physiology 20071201

Title: Statin reverses reduction of adiponectin receptor expression in infarcted heart and in TNF-alpha-treated cardiomyocytes in association with improved glucose uptake.

Journal: American journal of physiology. Heart and circulatory physiology 20071201

Title: The new acyl-CoA cholesterol acyltransferase inhibitor SMP-797 does not interact with statins via OATP1B1 in human cryopreserved hepatocytes and oocytes expressing systems.

Journal: Biopharmaceutics & drug disposition 20071201

Title: P-glycoprotein is downregulated in KG1a-primitive leukemia cells by LDL cholesterol deprivation and by HMG-CoA reductase inhibitors.

Journal: Experimental hematology 20071201

Title: Multichannel liquid chromatography-tandem mass spectrometry cocktail method for comprehensive substrate characterization of multidrug resistance-associated protein 4 transporter.

Journal: Pharmaceutical research 20071201

Title: Effects of initiation and acute withdrawal of statins on the neurovascular coupling mechanism in healthy, normocholesterolemic humans.

Journal: Stroke 20071201

Title: Olmesartan and pravastatin additively reduce development of atherosclerosis in APOE*3Leiden transgenic mice.

Journal: Journal of hypertension 20071201

Title: Patient complexity: more than comorbidity. the vector model of complexity.

Journal: Journal of general internal medicine 20071201

Title: Importance of intensive lipid lowering in acute coronary syndrome and percutaneous coronary intervention.

Journal: Journal of interventional cardiology 20071201

Title: Pravastatin induces rat aortic endothelial cell proliferation and migration via activation of PI3K/Akt/mTOR/p70 S6 kinase signaling.

Journal: Journal of pharmacological sciences 20071201

Title: A comparison of the effectiveness of lipid-lowering therapy between HIV- and non-HIV-infected subjects with hyperlipidaemia.

Journal: International journal of STD & AIDS 20071201

Title: Biological effects of acute pravastatin treatment in patients after aneurysmal subarachnoid hemorrhage: a double-blind, placebo-controlled trial.

Journal: Journal of neurosurgery 20071201

Title: The antitumour activities of statins.

Journal: Current oncology (Toronto, Ont.) 20071201

Title: Zoledronic acid affects over-angiogenic phenotype of endothelial cells in patients with multiple myeloma.

Journal: Molecular cancer therapeutics 20071201

Title: Evaluation of proton pump inhibitor use in patients with acute coronary syndromes based on risk factors for gastrointestinal bleed.

Journal: Critical pathways in cardiology 20071201

Title: Production of secondary metabolites by some terverticillate penicillia on carbohydrate-rich and meat substrates.

Journal: Journal of food protection 20071201

Title: Understanding practice patterns and low-density lipoprotein cholesterol goal attainment implications of switching patients from simvastatin in a health plan setting.

Journal: The American journal of managed care 20071201

Title: Down-regulation of intestinal multidrug resistance-associated protein 2 in long-evans cinnamon rats.

Journal: Drug metabolism and pharmacokinetics 20071201

Title: A review of nateglinide in the management of patients with type 2 diabetes.

Journal: Vascular health and risk management 20071201

Title: Endothelial dysfunction in diabetes mellitus.

Journal: Vascular health and risk management 20071201

Title: Rationale for multiple risk intervention: the need to move from theory to practice.

Journal: Vascular health and risk management 20071201

Title: Secular trends in lipid-lowering treatment and lipid levels after a first acute myocardial infarction.

Journal: Vascular health and risk management 20071201

Title: Short-term effect of the HMG-CoA reductase inhibitor rosuvastatin on erythrocyte nitric oxide synthase activity.

Journal: Vascular health and risk management 20071201

Title: Treatment of non-alcoholic fatty liver disease.

Journal: Therapeutics and clinical risk management 20071201

Title: Anti-inflammatory and immune therapy for Alzheimer's disease: current status and future directions.

Journal: Current neuropharmacology 20071201

Title: Postischemic administration of HMG CoA reductase inhibitor inhibits infarct expansion after transient middle cerebral artery occlusion.

Journal: Brain research 20071121

Title: Effect of withdrawal of pravastatin therapy on C-reactive protein and low-density lipoprotein cholesterol.

Journal: The American journal of cardiology 20071115

Title: Efficacy and safety of high-dose pravastatin in hypercholesterolemic patients with well-compensated chronic liver disease: Results of a prospective, randomized, double-blind, placebo-controlled, multicenter trial.

Journal: Hepatology (Baltimore, Md.) 20071101

Title: Society already achieves economic benefits from generic substitution but fails to do the same for therapeutic substitution.

Journal: British journal of clinical pharmacology 20071101

Title: Decreased plasma soluble RAGE in patients with hypercholesterolemia: effects of statins.

Journal: Free radical biology & medicine 20071101

Title: Is there life after plaque rupture?

Journal: Biochemical Society transactions 20071101

Title: Bilateral pleural effusions associated with pravastatin sodium treatment.

Journal: The European respiratory journal 20071101

Title: Association between apolipoprotein E4 and cognitive decline in elderly adults.

Journal: Journal of the American Geriatrics Society 20071101

Title: A comparison between the effects of hydrophobic and hydrophilic statins on osteoclast function in vitro and ovariectomy-induced bone loss in vivo.

Journal: Calcified tissue international 20071101

Title: Synergistic activity of the histone deacetylase inhibitor suberoylanilide hydroxamic acid and the bisphosphonate zoledronic acid against prostate cancer cells in vitro.

Journal: Molecular cancer therapeutics 20071101

Title: Comparative evaluation of the effects of statins on human stem and cancer cells in vitro.

Journal: Reproductive biomedicine online 20071101

Title: Titration patterns with rosuvastatin as compared with other statins in clinical practice: a retrospective observational cohort study using an electronic medical record database.

Journal: Clinical therapeutics 20071101

Title: Long-term follow-up of the West of Scotland Coronary Prevention Study.

Journal: The New England journal of medicine 20071011

Title: Primary prevention of coronary artery disease.

Journal: The New England journal of medicine 20071011

Title: Pravastatin improved glucose metabolism associated with increasing plasma adiponectin in patients with impaired glucose tolerance and coronary artery disease.

Journal: Atherosclerosis 20071001

Title: Anti-inflammatory effects of pravastatin on Helicobacter pylori-induced gastritis in mice.

Journal: Digestive diseases and sciences 20071001

Title: Risk of congenital anomalies in pregnant users of statin drugs.

Journal: British journal of clinical pharmacology 20071001

Title: Salicylic acid-induced taxol production and isopentenyl pyrophosphate biosynthesis in suspension cultures of Taxus chinensis var. mairei.

Journal: Cell biology international 20071001

Title: Growth hormone (GH) replacement decreases serum total and LDL-cholesterol in hypopituitary patients on maintenance HMG CoA reductase inhibitor (statin) therapy.

Journal: Clinical endocrinology 20071001

Title: P-glycoprotein has differential effects on the disposition of statin acid and lactone forms in mdr1a/b knockout and wild-type mice.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20071001

Title: From old organisms to new molecules: integrative biology and therapeutic targets in accelerated human ageing.

Journal: Cellular and molecular life sciences : CMLS 20071001

Title: Effectiveness of statins in Medicare-eligible patients and patients < 65 years using clinical practice data.

Journal: International journal of clinical practice 20071001

Title: Effect of intensive lipid-lowering therapy on mortality after acute coronary syndrome (a patient-level analysis of the Aggrastat to Zocor and Pravastatin or Atorvastatin Evaluation and Infection Therapy-Thrombolysis in Myocardial Infarction 22 trials).

Journal: The American journal of cardiology 20071001

Title: Impact of C-reactive protein on treatment of patients with cardiovascular disease.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20071001

Title: Pravastatin reduces myocardial infarct size via increasing protein kinase C-dependent nitric oxide, decreasing oxyradicals and opening the mitochondrial adenosine triphosphate-sensitive potassium channels in rabbits.

Journal: Circulation journal : official journal of the Japanese Circulation Society 20071001

Title: Life style-related diseases of the digestive system: cell culture system for the screening of anti-hepatitis C virus (HCV) reagents: suppression of HCV replication by statins and synergistic action with interferon.

Journal: Journal of pharmacological sciences 20071001

Title: A meta-analysis to evaluate the efficacy of statins in children with familial hypercholesterolemia.

Journal: International journal of clinical pharmacology and therapeutics 20071001

Title: Inhibition of balloon injury-induced neointimal formation by olmesartan and pravastatin in rats with insulin resistance.

Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20071001

Title: Comparison of the efficacies of five different statins on inhibition of human saphenous vein smooth muscle cell proliferation and invasion.

Journal: Journal of cardiovascular pharmacology 20071001

Title: The role of HMG-CoA reductase inhibition in endothelial dysfunction and inflammation.

Journal: Vascular health and risk management 20071001

Title: Are pleiotropic effects of statins real?

Journal: Vascular health and risk management 20071001

Title: Cholesterol lowering for secondary prevention: what statin dose should we use?

Journal: Vascular health and risk management 20071001

Title: Nebivolol in the treatment of chronic heart failure.

Journal: Vascular health and risk management 20071001

Title: Can combining different risk interventions into a single formulation contribute to improved cardiovascular disease risk reduction? The single pill of amlodipine/atorvastatin.

Journal: Vascular health and risk management 20071001

Title: Colesevelam hydrochloride: reducing atherosclerotic coronary heart disease risk factors.

Journal: Vascular health and risk management 20071001

Title: Primary prevention of cardiovascular disease with pravastatin.

Journal: Current atherosclerosis reports 20071001

Title: Progress update: Pharmacological treatment of Alzheimer's disease.

Journal: Neuropsychiatric disease and treatment 20071001

Title: Effective uptake of N-acetylglucosamine-conjugated liposomes by cardiomyocytes in vitro.

Journal: Journal of controlled release : official journal of the Controlled Release Society 20070926

Title: Meta-analysis of the role of statin therapy in reducing myocardial infarction following elective percutaneous coronary intervention.

Journal: The American journal of cardiology 20070915

Title: Pravastatin Inhibits the Rho/CCN2/extracellular matrix cascade in human fibrosis explants and improves radiation-induced intestinal fibrosis in rats.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20070915

Title: Inhibition of the mevalonate pathway and activation of p38 MAP kinase are independently regulated by nitrogen-containing bisphosphonates in breast cancer cells.

Journal: European journal of pharmacology 20070910

Title: In vivo coronary plaque histology in patients with stable and acute coronary syndromes: relationships with hyperlipidemic status and statin treatment.

Journal: Atherosclerosis 20070901

Title: A pravastatin dose-escalation study in systemic lupus erythematosus.

Journal: Rheumatology international 20070901

Title: SLCO1B1 521T-->C functional genetic polymorphism and lipid-lowering efficacy of multiple-dose pravastatin in Chinese coronary heart disease patients.

Journal: British journal of clinical pharmacology 20070901

Title: Modulation of ADP-induced platelet activation by aspirin and pravastatin: role of lectin-like oxidized low-density lipoprotein receptor-1, nitric oxide, oxidative stress, and inside-out integrin signaling.

Journal: The Journal of pharmacology and experimental therapeutics 20070901

Title: Involvement of rat and human organic anion transporter 3 in the renal tubular secretion of topotecan [(S)-9-dimethylaminomethyl-10-hydroxy-camptothecin hydrochloride].

Journal: The Journal of pharmacology and experimental therapeutics 20070901

Title: Genetic analysis of fluvastatin response and dyslipidemia in renal transplant recipients.

Journal: Journal of lipid research 20070901

Title: The contribution of organic anion transporters OAT1 and OAT3 to the renal uptake of rosuvastatin.

Journal: The Journal of pharmacology and experimental therapeutics 20070901

Title: Physiogenomic association of statin-related myalgia to serotonin receptors.

Journal: Muscle & nerve 20070901

Title: Flow cytometric evaluation of synergistic pro-apoptotic effects of statins and clofibrates in IM-9 human lymphoblasts.

Journal: Clinical and experimental pharmacology & physiology 20070901

Title: Effectiveness of rosuvastatin in low-density lipoprotein cholesterol lowering and National Cholesterol Education Program Adult Treatment Panel guideline III LDL-C goal attainment compared to other statins among diabetes mellitus patients: a retrospective study using an electronic medical records dataset in the United States.

Journal: Current medical research and opinion 20070901

Title: Usefulness of hydrophilic vs lipophilic statins after acute myocardial infarction: subanalysis of MUSASHI-AMI.

Journal: Circulation journal : official journal of the Japanese Circulation Society 20070901

Title: Simvastatin enhances induction of inducible nitric oxide synthase in 3T3-L1 adipocytes.

Journal: Free radical research 20070901

Title: Ezetimibe in heart transplantation: initial experience.

Journal: Transplantation proceedings 20070901

Title: Plasma 24S hydroxycholesterol response to statins in Alzheimer's disease patients: effects of gender, CYP46, and ApoE polymorphisms.

Journal: Journal of molecular neuroscience : MN 20070901

Title: Low-density lipoprotein cholesterol (LDL-C) levels and LDL-C goal attainment among elderly patients treated with rosuvastatin compared with other statins in routine clinical practice.

Journal: The American journal of geriatric pharmacotherapy 20070901

Title: [The antiplatelet effect of clopidogrel is not attenuated by statin treatment in patients with acute coronary syndromes undergone coronary stenting].

Journal: Zhonghua xin xue guan bing za zhi 20070901

Title: Retraction: Zheng Z, Chen B. Effects of Pravastatin on neuroprotection and neurogenesis after cerebral ischemia in rats. Neuroscience Bulletin 2007,23(4):189-197.

Journal: Neuroscience bulletin 20070901

Title: Use of lipid-modulating drugs in complicated course of coronary heart disease.

Journal: Bulletin of experimental biology and medicine 20070901

Title: Strategies for eliminating PrP(c) as substrate for prion conversion and for enhancing PrP(Sc) degradation.

Journal: Veterinary microbiology 20070831

Title: Statin therapy is associated with reduced neuropathologic changes of Alzheimer disease.

Journal: Neurology 20070828

Title: Formation of amyloids by Abeta-(1-42) on NGF-differentiated PC12 cells: roles of gangliosides and cholesterol.

Journal: Journal of molecular biology 20070824

Title: The application of microbore UPLC/oa-TOF-MS and 1H NMR spectroscopy to the metabonomic analysis of rat urine following the intravenous administration of pravastatin.

Journal: Journal of pharmaceutical and biomedical analysis 20070815

Title: Statin treatment in children with familial hypercholesterolemia: the younger, the better.

Journal: Circulation 20070807

Title: Stimulation programs for pediatric drug research--do children really benefit?

Journal: European journal of pediatrics 20070801

Title: Chemotherapy and zoledronate sensitize solid tumour cells to Vgamma9Vdelta2 T cell cytotoxicity.

Journal: Cancer immunology, immunotherapy : CII 20070801

Title: Statins in elderly patients with acute coronary syndrome: an analysis of dose and class effects in typical practice.

Journal: Heart (British Cardiac Society) 20070801

Title: Effect of reduced levels of the LDL receptor of Ehrlich ascites tumor cells on cholesterol uptake and cell proliferation: a coculture study with baby hamster kidney cells.

Journal: Cell biology international 20070801

Title: Atorvastatin glucuronidation is minimally and nonselectively inhibited by the fibrates gemfibrozil, fenofibrate, and fenofibric acid.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20070801

Title: Substrate-dependent drug-drug interactions between gemfibrozil, fluvastatin and other organic anion-transporting peptide (OATP) substrates on OATP1B1, OATP2B1, and OATP1B3.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20070801

Title: Apolipoprotein E polymorphisms influence effect of pravastatin on survival after myocardial infarction in a Mediterranean population: the GISSI-Prevenzione study.

Journal: European heart journal 20070801

Title: Cholesterol lowering with statins: how WOSCOPS confounded the skeptics.

Journal: Atherosclerosis. Supplements 20070801

Title: Primary prevention of cardiovascular diseases among hypercholesterolemic Japanese with a low dose of pravastatin.

Journal: Atherosclerosis. Supplements 20070801

Title: A trilogy of primary prevention statin trials. Panel discussion.

Journal: Atherosclerosis. Supplements 20070801

Title: Effect of drug transporter genotypes on pravastatin disposition in European- and African-American participants.

Journal: Pharmacogenetics and genomics 20070801

Title: Low HDL-C predicts the onset of transplant vasculopathy in pediatric cardiac recipients on pravastatin therapy.

Journal: Pediatric transplantation 20070801

Title: On the factors modulating the effect of statins on malignant cell proliferation.

Journal: Cancer investigation 20070801

Title: Successful mitigation of delayed intestinal radiation injury using pravastatin is not associated with acute injury improvement or tumor protection.

Journal: International journal of radiation oncology, biology, physics 20070801

Title: Impact of statin dosing intensity on transaminase and creatine kinase.

Journal: The American journal of medicine 20070801

Title: [Case report of cholesterol crystal embolism 1 month after carotid stenting].

Journal: No shinkei geka. Neurological surgery 20070801

Title: Strategies in the treatment of HIV-1-associated adipose redistribution syndromes.

Journal: Expert opinion on pharmacotherapy 20070801

Title: PROactive 07: pioglitazone in the treatment of type 2 diabetes: results of the PROactive study.

Journal: Vascular health and risk management 20070801

Title: Review of tipranavir in the treatment of drug-resistant HIV.

Journal: Therapeutics and clinical risk management 20070801

Title: [Effects of pravastatin on the expression of endothelin induced by aldosterone in rat cardiac fibroblasts].

Journal: Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 20070801

Title: Effect of the magnitude of lipid lowering on risk of elevated liver enzymes, rhabdomyolysis, and cancer: insights from large randomized statin trials.

Journal: Journal of the American College of Cardiology 20070731

Title: Lack of evidence of a clopidogrel-statin interaction in the CHARISMA trial.

Journal: Journal of the American College of Cardiology 20070724

Title: Sterol regulatory element-binding protein-2- and liver X receptor-driven dual promoter regulation of hepatic ABC transporter A1 gene expression: mechanism underlying the unique response to cellular cholesterol status.

Journal: The Journal of biological chemistry 20070720

Title: Effect of statin withdrawal on frequency of cardiac events after vascular surgery.

Journal: The American journal of cardiology 20070715

Title: A new compound-specific pleiotropic effect of statins: modification of plasma gamma-tocopherol levels.

Journal: Atherosclerosis 20070701

Title: RhoA-dependent PAI-1 gene expression induced in endothelial cells by monocyte adhesion mediates geranylgeranyl transferase I and Ca2+ signaling.

Journal: Atherosclerosis 20070701

Title: SREBP-1 regulates the expression of heme oxygenase 1 and the phosphatidylinositol-3 kinase regulatory subunit p55 gamma.

Journal: Journal of lipid research 20070701

Title: Simvastatin suppresses self-renewal of mouse embryonic stem cells by inhibiting RhoA geranylgeranylation.

Journal: Stem cells (Dayton, Ohio) 20070701

Title: Rac1, RhoA, and Cdc42 participate in HeLa cell invasion by group B streptococcus.

Journal: FEMS microbiology letters 20070701

Title: Statins and cancer.

Journal: Epidemiology (Cambridge, Mass.) 20070701

Title: Effects of Pravastatin on neuroprotection and neurogenesis after cerebral ischemia in rats.

Journal: Neuroscience bulletin 20070701

Title: [The primary observation on the effect of pravastatin to non-ischemic heart failure].

Journal: Zhonghua xin xue guan bing za zhi 20070701

Title: Treatment strategies for HIV lipodystrophy.

Journal: Current opinion in HIV and AIDS 20070701

Title: Chromatography-mass spectrometry methods for the quantitation of statins in biological samples.

Journal: Journal of pharmaceutical and biomedical analysis 20070628

Title: Effect of a treatment strategy consisting of pravastatin, vitamin E, and homocysteine lowering on carotid intima-media thickness, endothelial function, and renal function in patients with mild to moderate chronic kidney disease: results from the Anti-Oxidant Therapy in Chronic Renal Insufficiency (ATIC) Study.

Journal: Archives of internal medicine 20070625

Title: Long-term prognostic value of neopterin: a novel marker of monocyte activation in patients with acute coronary syndrome.

Journal: Circulation 20070619

Title: Pravastatin induces thrombomodulin expression in TNFalpha-treated human aortic endothelial cells by inhibiting Rac1 and Cdc42 translocation and activity.

Journal: Journal of cellular biochemistry 20070601

Title: Modulation of COX-2 expression by statins in human monocytic cells.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20070601

Title: Asbestos induces nitric oxide synthesis in mesothelioma cells via Rho signaling inhibition.

Journal: American journal of respiratory cell and molecular biology 20070601

Title: Use of hepatocytes to assess the contribution of hepatic uptake to clearance in vivo.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20070601

Title: Effect of pravastatin treatment on Chlamydia pneumoniae infection, inflammation and serum lipids in NIH/S mice.

Journal: International journal of antimicrobial agents 20070601

Title: Preferable effect of pravastatin compared to atorvastatin on beta cell function in Japanese early-state type 2 diabetes with hypercholesterolemia.

Journal: Endocrine journal 20070601

Title: Action profiles of statins and calcineurin inhibitors during human mixed lymphocyte reaction.

Journal: Clinical immunology (Orlando, Fla.) 20070601

Title: Effect of pravastatin on markers of endothelial activation in dialysis patients.

Journal: Nephrology (Carlton, Vic.) 20070601

Title: Difference in early effects of statin therapy on coronary and forearm flow reserve in postmenopausal hypercholesterolemic women.

Journal: Circulation journal : official journal of the Japanese Circulation Society 20070601

Title: The effects of statin and fibrate on lowering small dense LDL- cholesterol in hyperlipidemic patients with type 2 diabetes.

Journal: Journal of atherosclerosis and thrombosis 20070601

Title: Multivariate risk assessment and risk score cards in hypertension.

Journal: Vascular health and risk management 20070601

Title: Reducing the risks of cardiovascular disease in liver allograft recipients.

Journal: Transplantation 20070515

Title: Effects of pravastatin in murine collagen-induced arthritis.

Journal: Rheumatology international 20070501

Title: Synergistic effects of pravastatin and pioglitazone in renal tubular epithelial cells induced by transforming growth factor-beta1.

Journal: Cell biology international 20070501

Title: The influence of macrolide antibiotics on the uptake of organic anions and drugs mediated by OATP1B1 and OATP1B3.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20070501

Title: Amiodarone interacts with simvastatin but not with pravastatin disposition kinetics.

Journal: Clinical pharmacology and therapeutics 20070501

Title: Effects of acute pravastatin treatment on intensity of rescue therapy, length of inpatient stay, and 6-month outcome in patients after aneurysmal subarachnoid hemorrhage.

Journal: Stroke 20070501

Title: Drug-induced liver disease in 2006.

Journal: Current opinion in gastroenterology 20070501

Title: Effect of HMGCoA reductase inhibitors on cytochrome P450 expression in endothelial cell line.

Journal: Journal of cardiovascular pharmacology 20070501

Title: Gemfibrozil and its glucuronide inhibit the hepatic uptake of pravastatin mediated by OATP1B1.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20070501

Title: Which statin, what dose?

Journal: Drug and therapeutics bulletin 20070501

Title: Indian medicinal mushrooms as a source of antioxidant and antitumor agents.

Journal: Journal of clinical biochemistry and nutrition 20070501

Title: Protective effects of coenzyme q(10) on decreased oxidative stress resistance induced by simvastatin.

Journal: Journal of clinical biochemistry and nutrition 20070501

Title: Blockade of adaptive defensive changes in cholesterol uptake and synthesis in AML by the addition of pravastatin to idarubicin + high-dose Ara-C: a phase 1 study.

Journal: Blood 20070401

Title: Amelioration of steroids and cyclosporine-resistant nephrotic syndrome by pravastatin.

Journal: Pediatric nephrology (Berlin, Germany) 20070401

Title: Comparison of the antiatherosclerotic effects of dihydropyridine calcium channel blocker and HMG-CoA reductase inhibitor on hypercholesterolemic rabbits.

Journal: Vascular pharmacology 20070401

Title: Tissue factor and nitric oxide: a controversial relationship!

Journal: Journal of thrombosis and thrombolysis 20070401

Title: Decline in total cerebral blood flow is linked with increase in periventricular but not deep white matter hyperintensities.

Journal: Radiology 20070401

Title: Pravastatin decreases wall shear stress and blood velocity in the internal carotid artery without affecting flow volume: results from the PROSPER MRI study.

Journal: Stroke 20070401

Title: The effect of aggressive versus conventional lipid-lowering therapy on markers of inflammatory and oxidative stress.

Journal: Cardiovascular drugs and therapy 20070401

Title: Nitropravastatin stimulates reparative neovascularisation and improves recovery from limb Ischaemia in type-1 diabetic mice.

Journal: British journal of pharmacology 20070401

Title: Acquired ichthyosis with pravastatin.

Journal: Journal of the European Academy of Dermatology and Venereology : JEADV 20070401

Title: A systematic review and economic evaluation of statins for the prevention of coronary events.

Journal: Health technology assessment (Winchester, England) 20070401

Title: Inhibition of human organic anion transporter 3 mediated pravastatin transport by gemfibrozil and the metabolites in humans.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20070401

Title: Genetic variation in the interleukin-10 gene promoter and risk of coronary and cerebrovascular events: the PROSPER study.

Journal: Annals of the New York Academy of Sciences 20070401

Title: Characterization of Salmonella enterica serovar Typhimurium DT104 invasion in an epithelial cell line (IPEC J2) from porcine small intestine.

Journal: Veterinary microbiology 20070310

Title: Effects of pravastatin on ventricular remodeling by activation of myocardial KATP channels in infarcted rats: role of 70-kDa S6 kinase.

Journal: Basic research in cardiology 20070301

Title: Cholesterol-dependent balance between evoked and spontaneous synaptic vesicle recycling.

Journal: The Journal of physiology 20070301

Title: Pravastatin enhances beneficial effects of olmesartan on vascular injury of salt-sensitive hypertensive rats, via pleiotropic effects.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20070301

Title: Predicting the oxidative metabolism of statins: an application of the MetaSite algorithm.

Journal: Pharmaceutical research 20070301

Title: Statins and renal function. Is the compound and dose making a difference?

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20070301

Title: Pravastatin inhibits arrhythmias induced by coronary artery ischemia in anesthetized rats.

Journal: Journal of pharmacological sciences 20070301

Title: Impact of gender on statin efficacy.

Journal: Current medical research and opinion 20070301

Title: Two-week treatment with pravastatin improves ventriculo-vascular haemodynamic interactions in young men with type 1 diabetes.

Journal: Diabetes & vascular disease research 20070301

Title: Neuropsychiatric consequences of cardiovascular medications.

Journal: Dialogues in clinical neuroscience 20070301

Title: C-reactive protein and prediction of coronary heart disease and global vascular events in the Prospective Study of Pravastatin in the Elderly at Risk (PROSPER).

Journal: Circulation 20070227

Title: Pravastatin and cancer: an unproven association.

Journal: CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20070227

Title: Does pravastatin promote cancer in elderly patients? A meta-analysis.

Journal: CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20070227

Title: Effects of intensive versus moderate lipid-lowering therapy on myocardial ischemia in older patients with coronary heart disease: results of the Study Assessing Goals in the Elderly (SAGE).

Journal: Circulation 20070213

Title: Statin therapy and the elderly: SAGE advice?

Journal: Circulation 20070213

Title: Gas6/Axl-PI3K/Akt pathway plays a central role in the effect of statins on inorganic phosphate-induced calcification of vascular smooth muscle cells.

Journal: European journal of pharmacology 20070205

Title: Systematic review and meta-analysis of clinically relevant adverse events from HMG CoA reductase inhibitor trials worldwide from 1982 to present.

Journal: Pharmacoepidemiology and drug safety 20070201

Title: Development and validation of a preclinical food effect model.

Journal: Journal of pharmaceutical sciences 20070201

Title: Effect of colestimide therapy for glycemic control in type 2 diabetes mellitus with hypercholesterolemia.

Journal: Endocrine journal 20070201

Title: Lipid raft-dependent endocytosis of metallothionein in HepG2 cells.

Journal: Journal of cellular physiology 20070201

Title: Severe citrate toxicity complicating volunteer apheresis platelet donation.

Journal: Journal of clinical apheresis 20070201

Title: Analysis of pharmaceuticals in wastewater and removal using a membrane bioreactor.

Journal: Analytical and bioanalytical chemistry 20070201

Title: [Medical treatment in peripheral arterial disease: a professional practice study in 262 patients].

Journal: La Revue de medecine interne 20070201

Title: Influence of drug transporter polymorphisms on pravastatin pharmacokinetics in humans.

Journal: Pharmaceutical research 20070201

Title: Lipophilic statins suppress cytotoxicity by freshly isolated natural killer cells through modulation of granule exocytosis.

Journal: International immunology 20070201

Title: Effect of atorvastatin and pravastatin on platelet inhibition by aspirin and clopidogrel treatment in patients with coronary stent thrombosis.

Journal: The American journal of cardiology 20070201

Title: Safety of lovastatin/extended release niacin compared with lovastatin alone, atorvastatin alone, pravastatin alone, and simvastatin alone (from the United States Food and Drug Administration adverse event reporting system).

Journal: The American journal of cardiology 20070201

Title: Estimating the impact of adding C-reactive protein as a criterion for lipid lowering treatment in the United States.

Journal: Journal of general internal medicine 20070201

Title: [Perspectives in the treatment of subarachnoid-hemorrhage-induced cerebral vasospasm].

Journal: Neurocirugia (Asturias, Spain) 20070201

Title: Meta-analysis of drug-induced adverse events associated with intensive-dose statin therapy.

Journal: Clinical therapeutics 20070201

Title: Effect of lipid-lowering and anti-hypertensive drugs on plasma homocysteine levels.

Journal: Vascular health and risk management 20070201

Title: [The comparison in vitro the effects of pravastatin and quercetin on the selected structural parameters of membrane erythrocytes from patients with hypercholesterolemia].

Journal: Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20070201

Title: Can telomere length predict cardiovascular risk?

Journal: Lancet (London, England) 20070113

Title: Telomere length, risk of coronary heart disease, and statin treatment in the West of Scotland Primary Prevention Study: a nested case-control study.

Journal: Lancet (London, England) 20070113

Title: The effect of statin on the aortic gene expression profiling.

Journal: International journal of cardiology 20070102

Title: Pravastatin reduces lung metastasis of rat hepatocellular carcinoma via a coordinated decrease of MMP expression and activity.

Journal: Journal of hepatology 20070101

Title: Enhanced cardiac production of matrix metalloproteinase-2 and -9 and its attenuation associated with pravastatin treatment in patients with acute myocardial infarction.

Journal: Clinical science (London, England : 1979) 20070101

Title: Pravastatin reverses the down-regulating effect of inflammation on beta-adrenergic receptors: a disease-drug interaction between inflammation, pravastatin, and propranolol.

Journal: Vascular pharmacology 20070101

Title: The nitric oxide-donating pravastatin derivative, NCX 6550 [(1S-[1alpha(betaS*, deltaS*), 2alpha, 6alpha, 8beta-(R*), 8a alpha]]-1,2,6,7,8,8a-Hexahydro-beta, delta, 6-trihydroxy-2-methyl-8-(2-methyl-1-oxobutoxy)-1-naphtalene-heptanoic acid 4-(nitrooxy)butyl ester)], reduces splenocyte adhesion and reactive oxygen species generation in normal and atherosclerotic mice.

Journal: The Journal of pharmacology and experimental therapeutics 20070101

Title: Modulation of human Niemann-Pick C1-like 1 gene expression by sterol: Role of sterol regulatory element binding protein 2.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20070101

Title: Vasoactive drugs enhance pancreatic islet blood flow, augment insulin secretion and improve glucose tolerance in female rats.

Journal: Clinical science (London, England : 1979) 20070101

Title: The value of the electrocardiogram in risk assessment in primary prevention: experience from the West of Scotland Coronary Prevention Study.

Journal: Journal of electrocardiology 20070101

Title: From pathophysiology to targeted therapy for atherothrombosis: a role for the combination of statin and aspirin in secondary prevention.

Journal: Pharmacology & therapeutics 20070101

Title: A rapid and specific approach for direct measurement of pravastatin concentration in plasma by LC-MS/MS employing solid-phase extraction.

Journal: Biomedical chromatography : BMC 20070101

Title: Impact of high dose statin trials on hospital prescribers.

Journal: European journal of clinical pharmacology 20070101

Title: Absence of an interaction between the angiotensin-converting enzyme insertion-deletion polymorphism and pravastatin on cardiovascular disease in high-risk hypertensive patients: the Genetics of Hypertension-Associated Treatment (GenHAT) study.

Journal: American heart journal 20070101

Title: Differential impact of atorvastatin vs pravastatin on progressive insulin resistance and left ventricular diastolic dysfunction in a rat model of type II diabetes.

Journal: Circulation journal : official journal of the Japanese Circulation Society 20070101

Title: Optimal low-density lipoprotein cholesterol lowering--morning versus evening statin administration.

Journal: The Annals of pharmacotherapy 20070101

Title: Probable statin-induced testicular pain.

Journal: The Annals of pharmacotherapy 20070101

Title: Immunization of LDL receptor-deficient mice with beta2-glycoprotein 1 or human serum albumin induces a more inflammatory phenotype in atherosclerotic plaques.

Journal: Thrombosis and haemostasis 20070101

Title: Update on heart disease. Evidence mounts for even lower LDL.

Journal: Diabetes self-management 20070101

Title: Drug-related hepatotoxicity in a renal transplant recipient with long-term survival and hepatitis C.

Journal: Annals of hepatology 20070101

Title: [Effect of hypolipidemic treatment on the composition of bile and the risk or cholesterol gallstone disease].

Journal: Casopis lekaru ceskych 20070101

Title: Pravastatin inhibits carboxymethyllysine-induced monocyte chemoattractant protein 1 expression in podocytes via prevention of signalling events.

Journal: Nephron. Experimental nephrology 20070101

Title: Effects of statins on restenosis after coronary stent implantation.

Journal: Angiology 20070101

Title: Safety of rosuvastatin: update on 16,876 rosuvastatin-treated patients in a multinational clinical trial program.

Journal: Cardiology 20070101

Title: Evidence for placebo effects on physical but not on biochemical outcome parameters: a review of clinical trials.

Journal: BMC medicine 20070101

Title: The Interleukin-6 inflammation pathway from cholesterol to aging--role of statins, bisphosphonates and plant polyphenols in aging and age-related diseases.

Journal: Immunity & ageing : I & A 20070101

Title: Asymptomatic statin-induced rhabdomyolysis after long-term therapy with the hydrophilic drug pravastatin.

Journal: Clinical therapeutics 20070101

Title: How equitable are GP practice prescribing rates for statins?: an ecological study in four primary care trusts in North West England.

Journal: International journal for equity in health 20070101

Title: The gender specific frequency of risk factor and CHD diagnoses prior to incident MI: a community study.

Journal: BMC family practice 20070101

Title: Synthesis of the oxysterol, 24(S), 25-epoxycholesterol, parallels cholesterol production and may protect against cellular accumulation of newly-synthesized cholesterol.

Journal: Lipids in health and disease 20070101

Title: Pravastatin in HIV-infected patients treated with protease inhibitors: a placebo-controlled randomized study.

Journal: HIV clinical trials 20070101

Title: Can clopidogrel monotherapy influence vascular remodeling?

Journal: Vascular and endovascular surgery 20070101

Title: Understanding the effects of a decentralized budget on physicians' compliance with guidelines for statin prescription--a multilevel methodological approach.

Journal: BMC health services research 20070101

Title: Generic drug policy in Australia: a community pharmacy perspective.

Journal: Australia and New Zealand health policy 20070101

Title: Statin's cost-effectiveness: a Canadian analysis of commonly prescribed generic and brand name statins.

Journal: The Canadian journal of clinical pharmacology = Journal canadien de pharmacologie clinique 20070101

Title: Essential and non-essential DNA replication genes in the model halophilic Archaeon, Halobacterium sp. NRC-1.

Journal: BMC genetics 20070101

Title: Ezetimibe is effective when added to maximally tolerated lipid lowering therapy in patients with HIV.

Journal: Lipids in health and disease 20070101

Title: Coronary reactivity, homocysteine and methylenetetrahydrofolate reductase gene variation in young men during pravastatin therapy.

Journal: Vascular pharmacology 20070101

Title: [Rhabdomyolysis probably caused by interaction between efalizumab and pravastatin].

Journal: Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria 20070101

Title: Severe rhabdomyolysis and acute renal failure secondary to concomitant use of simvastatin, amiodarone, and atazanavir.

Journal: Journal of the American Board of Family Medicine : JABFM 20070101

Title: Simvastatin is associated with a reduced incidence of dementia and Parkinson's disease.

Journal: BMC medicine 20070101

Title: Mevastatin increases eNO synthase expression and inhibits lipid peroxidation in human endothelial cells.

Journal: Clinical hemorheology and microcirculation 20070101

Title: HMG-CoA reductase inhibitors reduce nicotine-induced expression of cellular adhesion molecules in cultured human coronary endothelial cells.

Journal: Journal of vascular research 20070101

Title: Does pravastatin therapy affect cardiac enzyme levels after percutaneous coronary intervention?

Journal: Advances in therapy 20070101

Title: Analysis of factors associated with statin adherence in a hierarchical model considering physician, pharmacy, patient, and prescription characteristics.

Journal: Journal of managed care pharmacy : JMCP 20070101

Title: Clinical review: Prevention and therapy of vasospasm in subarachnoid hemorrhage.

Journal: Critical care (London, England) 20070101

Title: Can drug treatment prevent disease in common practice?

Journal: Zeitschrift fur arztliche Fortbildung und Qualitatssicherung 20070101

Title: Effect of medium pH on the cytotoxicity of hydrophilic statins.

Journal: Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20070101

Title: The PreCardio-study protocol--a randomized clinical trial of a multidisciplinary electronic cardiovascular prevention programme.

Journal: BMC cardiovascular disorders 20070101

Title: Estimation of treatment effect adjusting for dependent censoring using the IPCW method: an application to a large primary prevention study for coronary events (MEGA study).

Journal: Clinical trials (London, England) 20070101

Title: Improvement of myocardial blood flow by lipid-lowering therapy with pravastatin is modulated by apolipoprotein E genotype.

Journal: Scandinavian journal of clinical and laboratory investigation 20070101

Title: Locally applied Simvastatin improves fracture healing in mice.

Journal: BMC musculoskeletal disorders 20070101

Title: A genome-wide association study for blood lipid phenotypes in the Framingham Heart Study.

Journal: BMC medical genetics 20070101

Title: Effects of atorvastatin on the different phases of atherogenesis.

Journal: Drugs 20070101

Title: Atorvastatin efficacy in the primary and secondary prevention of cardiovascular events.

Journal: Drugs 20070101

Title: Atorvastatin efficacy in the prevention of cardiovascular events in patients with diabetes mellitus and/or metabolic syndrome.

Journal: Drugs 20070101

Title: Atorvastatin: its clinical role in cerebrovascular prevention.

Journal: Drugs 20070101

Title: Are HIV positive patients resistant to statin therapy?

Journal: Lipids in health and disease 20070101

Title: Fish-oil esters of plant sterols differ from vegetable-oil sterol esters in triglycerides lowering, carotenoid bioavailability and impact on plasminogen activator inhibitor-1 (PAI-1) concentrations in hypercholesterolemic subjects.

Journal: Lipids in health and disease 20070101

Title: Medicinal importance of grapefruit juice and its interaction with various drugs.

Journal: Nutrition journal 20070101

Title: Effects of long-term pravastatin treatment on serum and urinary monocyte chemoattractant protein-1 levels and renal function in type 2 diabetic patients with normoalbuminuria.

Journal: Renal failure 20070101

Title: Analysis of Schistosoma mansoni genes shared with Deuterostomia and with possible roles in host interactions.

Journal: BMC genomics 20070101

Title: Effect of pravastatin on phenotypical transformation of fibroblasts and hypertrophy of cardiomyocytes in culture.

Journal: Bulletin of experimental biology and medicine 20070101

Title: Effect of PlA1/A2 glycoprotein IIIa gene polymorphism on the long-term outcome after successful coronary stenting.

Journal: Thrombosis journal 20070101

Title: The Ontario printed educational message (OPEM) trial to narrow the evidence-practice gap with respect to prescribing practices of general and family physicians: a cluster randomized controlled trial, targeting the care of individuals with diabetes and hypertension in Ontario, Canada.

Journal: Implementation science : IS 20070101

Title: Atorvastatin: a pharmacoeconomic review of its use in the primary and secondary prevention of cardiovascular events.

Journal: PharmacoEconomics 20070101

Title: Aspects of statin prescribing in Norwegian counties with high, average and low statin consumption - an individual-level prescription database study.

Journal: BMC clinical pharmacology 20070101

Title: The effects of atorvastatin therapy on endothelial function in patients with coronary artery disease.

Journal: Cardiovascular ultrasound 20070101

Title: A critical gap between recommended and achieved LDL-cholesterol levels. Results of statin therapy in Slovakia.

Journal: Bratislavske lekarske listy 20070101

Title: [Hypercholesterolemia in men and women of various age. Part II. The problem of efficacy and safety of statins].

Journal: Kardiologiia 20070101

Title: [Long-term follow-up of the West of Scotland Coronary Prevention Study].

Journal: Kardiologiia 20070101

Title: Statins in hepatobiliary diseases: effects, indications and risks.

Journal: Acta gastro-enterologica Belgica 20070101

Title: Statin-Induced Increase in HDL-C and Renal Function in Coronary Heart Disease Patients.

Journal: The open cardiovascular medicine journal 20070101

Title: Atherosclerosis, cholesterol, nutrition, and statins--a critical review.

Journal: German medical science : GMS e-journal 20070101

Title: [Pravastatin and acetylsalycilic acid fixed-combination: a strategy to improve cardiovascular outcomes].

Journal: American journal of cardiovascular drugs : drugs, devices, and other interventions 20070101

Title: Effect of Coenzyme Q10 and green tea on plasma and liver lipids, platelet aggregation, TBARS production and erythrocyte Na leak in simvastatin treated hypercholesterolmic rats.

Journal: Nutrition research and practice 20070101

Title: Targeting receptors, transporters and site of absorption to improve oral drug delivery.

Journal: Drug target insights 20070101

Title: Crystalline polymorphism and molecular structure of sodium pravastatin.

Journal: The journal of physical chemistry. B 20061228

Title: Cholesterol depletion reduces serotonin binding and signaling via human 5-HT(7(a)) receptors.

Journal: European journal of pharmacology 20061215

Title: The MEGA study.

Journal: Lancet (London, England) 20061209

Title: The MEGA study.

Journal: Lancet (London, England) 20061209

Title: Beyond lipid lowering: What have we learned about the benefits of statins from the acute coronary syndromes trials?

Journal: The American journal of cardiology 20061204

Title: Molecular basis of differences among statins and a comparison with antioxidant vitamins.

Journal: The American journal of cardiology 20061204

Title: Effect of pravastatin on left ventricular mass in the two-kidney, one-clip hypertensive rats.

Journal: American journal of physiology. Heart and circulatory physiology 20061201

Title: Effect of levothyroxine on total lipid profiles as assessed by analytical capillary isotachophoresis in a patient with hypothyroidism.

Journal: Endocrine journal 20061201

Title: Asp92Asn polymorphism in the myeloid IgA Fc receptor is associated with myocardial infarction in two disparate populations: CARE and WOSCOPS.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20061201

Title: The safety and efficacy of achieving very low LDL-cholesterol concentrations with high dose statin therapy.

Journal: Current opinion in lipidology 20061201

Title: The protective effect of HMG-CoA reductase inhibitors against monocrotaline-induced pulmonary hypertension in the rat might not be a class effect: comparison of pravastatin and atorvastatin.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20061201

Title: [Multiple mononeuropathy associated to treatment with pravastatin].

Journal: Revista de neurologia 20061201

Title: Nicotinic acid: new/old drug. Immediate or sustained release: too risky for a drug with no proven benefit.

Journal: Prescrire international 20061201

Title: Drug interactions with lipid-lowering drugs: mechanisms and clinical relevance.

Journal: Clinical pharmacology and therapeutics 20061201

Title: Effect of statins on Alzheimer's disease biomarkers in cerebrospinal fluid.

Journal: Journal of Alzheimer's disease : JAD 20061201

Title: Preservation of the blood brain barrier integrity may underlie neuroprotective effects of statins in Alzheimer's disease.

Journal: Journal of Alzheimer's disease : JAD 20061201

Title: Influence of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors on ubiquinone levels in rat skeletal muscle and heart: relationship to cytotoxicity and inhibitory activity for cholesterol synthesis in human skeletal muscle cells.

Journal: Journal of atherosclerosis and thrombosis 20061201

Title: Distinct effects of pravastatin, atorvastatin, and simvastatin on insulin secretion from a beta-cell line, MIN6 cells.

Journal: Journal of atherosclerosis and thrombosis 20061201

Title: Effects of direct-to-consumer advertising of hydroxymethylglutaryl coenzyme a reductase inhibitors on attainment of LDL-C goals.

Journal: Clinical therapeutics 20061201

Title: Olmesartan medoxomil: current status of its use in monotherapy.

Journal: Vascular health and risk management 20061201

Title: Who should receive a statin drug to lower cardiovascular risk? Does the drug and the dose of the drug matter?

Journal: Vascular health and risk management 20061201

Title: HIV-associated lipodystrophy syndrome.

Journal: Collegium antropologicum 20061201

Title: Management of hyperlipidemia with statins in the older patient.

Journal: Clinical interventions in aging 20061201

Title: Influence of pravastatin on carotid artery structure and function in dyslipidemic HIV-infected patients receiving antiretroviral therapy.

Journal: AIDS (London, England) 20061128

Title: Pravastatin: a potential cause for acute pancreatitis.

Journal: World journal of gastroenterology 20061121

Title: Ezetimibe, a promising lipid-lowering agent for the treatment of dyslipidaemia in HIV-infected patients with poor response to statins.

Journal: AIDS (London, England) 20061114

Title: Multitherapy for diabetes.

Journal: CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20061107

Title: Paradoxical increase in lumen size during progression of coronary atherosclerosis: observations from the REVERSAL trial.

Journal: Atherosclerosis 20061101

Title: The effect of statins on urinary albumin excretion and glomerular filtration rate: results from both a randomized clinical trial and an observational cohort study.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20061101

Title: Association of genetic polymorphism in ABCC2 with hepatic multidrug resistance-associated protein 2 expression and pravastatin pharmacokinetics.

Journal: Pharmacogenetics and genomics 20061101

Title: The effect of statins on preservation of kidney function in patients with coronary artery disease.

Journal: Current opinion in cardiology 20061101

Title: Role of P-glycoprotein in statin drug interactions.

Journal: Pharmacotherapy 20061101

Title: Statins, fibrates, and melanoma risk: a systematic review and meta-analysis.

Journal: Journal of the National Cancer Institute 20061101

Title: Statins induce mammalian target of rapamycin (mTOR)-mediated inhibition of Akt signaling and sensitize p53-deficient cells to cytostatic drugs.

Journal: Molecular cancer therapeutics 20061101

Title: Spillover effects of restrictive drug formularies in the statin class: a descriptive study of the Medicaid preferred drug list in Texas.

Journal: Managed care interface 20061101

Title: Expanding options with a wider range of rosuvastatin doses.

Journal: Clinical therapeutics 20061101

Title: [J-STARS (Japan statin treatment against recurrent stroke)].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20061028

Title: Are statins analogues of vitamin D?

Journal: Lancet (London, England) 20061007

Title: Pharmacokinetic and pharmacodynamic alterations of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors: drug-drug interactions and interindividual differences in transporter and metabolic enzyme functions.

Journal: Pharmacology & therapeutics 20061001

Title: Angiotensin II-mediated oxidative stress and procollagen-1 expression in cardiac fibroblasts: blockade by pravastatin and pioglitazone.

Journal: American journal of physiology. Heart and circulatory physiology 20061001

Title: Internal mammary artery smooth muscle cells resist migration and possess high antioxidant capacity.

Journal: Cardiovascular research 20061001

Title: Statins and cerebral vasomotor reactivity: implications for a new therapy?

Journal: Stroke 20061001

Title: Calcification and cellularity in human aortic heart valve tissue determine the differentiation of bone-marrow-derived cells.

Journal: Journal of molecular and cellular cardiology 20061001

Title: Acute coronary syndromes and diabetes: Is intensive lipid lowering beneficial? Results of the PROVE IT-TIMI 22 trial.

Journal: European heart journal 20061001

Title: Mevastatin inhibits proliferation of rat ovarian theca-interstitial cells by blocking the mitogen-activated protein kinase pathway.

Journal: Fertility and sterility 20061001

Title: Toxicity of statins on rat skeletal muscle mitochondria.

Journal: Cellular and molecular life sciences : CMLS 20061001

Title: SLCO1B1 polymorphism and sex affect the pharmacokinetics of pravastatin but not fluvastatin.

Journal: Clinical pharmacology and therapeutics 20061001

Title: Not all age-related white matter hyperintensities are the same: a magnetization transfer imaging study.

Journal: AJNR. American journal of neuroradiology 20061001

Title: Rising to the challenge of treating high-risk patients.

Journal: The American journal of managed care 20061001

Title: A therapeutic dose of the lipophilic statin pitavastatin enhances oxidant-induced apoptosis in human vascular smooth muscle cells.

Journal: Journal of cardiovascular pharmacology 20061001

Title: Japan: are statins still good for everybody?

Journal: Lancet (London, England) 20060930

Title: Primary prevention of cardiovascular disease with pravastatin in Japan (MEGA Study): a prospective randomised controlled trial.

Journal: Lancet (London, England) 20060930

Title: MUBs, a family of ubiquitin-fold proteins that are plasma membrane-anchored by prenylation.

Journal: The Journal of biological chemistry 20060915

Title: Effects of acute treatment with statins on cerebral autoregulation in patients after aneurysmal subarachnoid hemorrhage.

Journal: Neurosurgical focus 20060915

Title: Additive effects of combined blockade of AT1 receptor and HMG-CoA reductase on left ventricular remodeling in infarcted rats.

Journal: American journal of physiology. Heart and circulatory physiology 20060901

Title: Statin therapy induces ultrastructural damage in skeletal muscle in patients without myalgia.

Journal: The Journal of pathology 20060901

Title: Pravastatin prolongs graft survival in an allogeneic rat model of orthotopic single lung transplantation.

Journal: European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 20060901

Title: The key role of apoptosis in the pathogenesis and treatment of pulmonary hypertension.

Journal: European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 20060901

Title: The HMG-CoA reductase inhibitor, pravastatin, prevents the development of monocrotaline-induced pulmonary hypertension in the rat through reduction of endothelial cell apoptosis and overexpression of eNOS.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20060901

Title: Protective effects of pravastatin in murine lipopolysaccharide-induced acute lung injury.

Journal: Clinical and experimental pharmacology & physiology 20060901

Title: Pravastatin prevents ischemia-reperfusion injury in rat sciatic nerve.

Journal: Surgical neurology 20060901

Title: Pravastatin decreases blood pressure in hypertensive and hypercholesterolemic patients receiving antihypertensive treatment.

Journal: Circulation journal : official journal of the Japanese Circulation Society 20060901

Title: Fluvastatin treatment is not associated with an increased incidence of cancer.

Journal: International journal of clinical practice 20060901

Title: Pravastatin use and the five-year incidence of cancer in coronary heart disease patients: from the prevention of coronary sclerosis study.

Journal: Journal of epidemiology 20060901

Title: Serum lipoprotein(a) dynamics before/after menopause and long-term effects of hormone replacement therapy on lipoprotein(a) levels in middle-aged and older Japanese women.

Journal: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20060901

Title: Differential efficacy of 3-hydroxy-3-methylglutaryl CoA reductase inhibitors on the cell cycle of prostate cancer cells.

Journal: Molecular cancer therapeutics 20060901

Title: Pravastatin in vivo reduces mononuclear cell migration through endothelial monolayers.

Journal: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20060901

Title: Critical appraisal of C-reactive protein throughout the spectrum of cardiovascular disease.

Journal: Vascular health and risk management 20060901

Title: A review of omega-3 ethyl esters for cardiovascular prevention and treatment of increased blood triglyceride levels.

Journal: Vascular health and risk management 20060901

Title: Vascular dementia: prevention and treatment.

Journal: Clinical interventions in aging 20060901

Title: Pleiotropic effects of statins and early benefit in the PROVE IT-TIMI-22 study.

Journal: Journal of the American College of Cardiology 20060815

Title: Pitavastatin-induced downregulation of CCR2 and CCR5 in monocytes is associated with the arrest of cell-cycle in S phase.

Journal: Atherosclerosis 20060801

Title: Effect of pravastatin on blood pressure in people with cardiovascular disease.

Journal: Journal of human hypertension 20060801

Title: 25-Hydroxycholesterol has a dual effect on the proliferation of cultured rat astrocytes.

Journal: Neuropharmacology 20060801

Title: Hypothesis: the antitumor activities of statins may be mediated by IL-18.

Journal: Journal of leukocyte biology 20060801

Title: Cholesterol, C-reactive protein, and cerebrovascular events following intensive and moderate statin therapy.

Journal: Journal of thrombosis and thrombolysis 20060801

Title: Association of statin therapy and increased survival in patients with multiple organ dysfunction syndrome.

Journal: Intensive care medicine 20060801

Title: Screening of compactin-resistant microorganisms capable of converting compactin to pravastatin.

Journal: Current microbiology 20060801

Title: Statin treatment is not associated with consistent alterations in inflammatory status of carotid atherosclerotic plaques: a retrospective study in 378 patients undergoing carotid endarterectomy.

Journal: Stroke 20060801

Title: Cholesteryl ester transfer protein inhibition, high-density lipoprotein metabolism and heart disease risk reduction.

Journal: Current opinion in lipidology 20060801

Title: Potential clinical utility of high-density lipoprotein-mimetic peptides.

Journal: Current opinion in lipidology 20060801

Title: Protective effect of pravastatin on vascular endothelium in patients with systemic sclerosis: a pilot study.

Journal: Annals of the rheumatic diseases 20060801

Title: Insulin generates free radicals in human fibroblasts ex vivo by a protein kinase C-dependent mechanism, which is inhibited by pravastatin.

Journal: Free radical biology & medicine 20060801

Title: Clopidogrel-statin interaction: a mountain or a mole hill?

Journal: American heart journal 20060801

Title: The 4G/5G PAI-1 polymorphism influences the endothelial response to IL-1 and the modulatory effect of pravastatin.

Journal: Journal of thrombosis and haemostasis : JTH 20060801

Title: Plasma cholesteryl ester transfer protein concentrations predict cardiovascular events in patients with coronary artery disease treated with pravastatin.

Journal: Journal of internal medicine 20060801

Title: The effects of HMG-CoA reductase inhibitor on vascular progenitor cells.

Journal: Journal of pharmacological sciences 20060801

Title: Repression of smoothened by patched-dependent (pro-)vitamin D3 secretion.

Journal: PLoS biology 20060801

Title: Statins, fracture risk, and bone remodeling: What is true?

Journal: The American journal of the medical sciences 20060801

Title: Pravastatin prevents myocardium from ischemia-induced fibrosis by protecting vascular endothelial cells exposed to oxidative stress.

Journal: Cardiovascular drugs and therapy 20060801

Title: Statins in the treatment of chronic heart failure: a systematic review.

Journal: PLoS medicine 20060801

Title: Statins, especially atorvastatin, may improve survival following brachytherapy for clinically localized prostate cancer.

Journal: Urologic nursing 20060801

Title: Both hepatitis C virus and Chlamydia pneumoniae infection are related to the progression of carotid atherosclerosis in patients undergoing lipid lowering therapy.

Journal: Fukuoka igaku zasshi = Hukuoka acta medica 20060801

Title: The role of the central melanocortin system in the regulation of food intake and energy homeostasis: lessons from mouse models.

Journal: Philosophical transactions of the Royal Society of London. Series B, Biological sciences 20060729

Title: Pancreatic islet blood flow is selectively enhanced by captopril, irbesartan and pravastatin, and suppressed by palmitate.

Journal: Biochemical and biophysical research communications 20060721

Title: The year in non-ST-segment elevation acute coronary syndromes.

Journal: Journal of the American College of Cardiology 20060718

Title: Regulation of retinal dehydrogenases and retinoic acid synthesis by cholesterol metabolites.

Journal: The EMBO journal 20060712

Title: Endothelial Protection, AT1 blockade and Cholesterol-Dependent Oxidative Stress: the EPAS trial.

Journal: Circulation 20060704

Title: Neither plasma coenzyme Q10 concentration, nor its decline during pravastatin therapy, is linked to recurrent cardiovascular disease events: a prospective case-control study from the LIPID study.

Journal: Atherosclerosis 20060701

Title: Statins revert doxorubicin resistance via nitric oxide in malignant mesothelioma.

Journal: International journal of cancer 20060701

Title: Predominant contribution of OATP1B3 to the hepatic uptake of telmisartan, an angiotensin II receptor antagonist, in humans.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20060701

Title: Cyclodextrins but not compactin inhibit the lateral diffusion of membrane proteins independent of cholesterol.

Journal: Traffic (Copenhagen, Denmark) 20060701

Title: Different anti-HCV profiles of statins and their potential for combination therapy with interferon.

Journal: Hepatology (Baltimore, Md.) 20060701

Title: Management of cardiovascular risk in patients receiving calcineurin inhibitors--a case report.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20060701

Title: Persistence and adherence to cholesterol lowering agents: evidence from Régie de l'Assurance Maladie du Québec data.

Journal: American heart journal 20060701

Title: Pravastatin reduces microvascular basal lamina damage following focal cerebral ischemia and reperfusion.

Journal: The European journal of neuroscience 20060701

Title: Statin but not non-statin lipid-lowering drugs decrease fracture risk: a nation-wide case-control study.

Journal: Calcified tissue international 20060701

Title: Combination therapy with ezetimibe and simvastatin to achieve aggressive LDL reduction.

Journal: Expert review of cardiovascular therapy 20060701

Title: The effect of 6 months of treatment with pravastatin on serum adiponection concentrations in Japanese patients with coronary artery disease and hypercholesterolemia: a pilot study.

Journal: Clinical therapeutics 20060701

Title: Determinants of arterial wall remodeling during lipid-lowering therapy: serial intravascular ultrasound observations from the Reversal of Atherosclerosis with Aggressive Lipid Lowering Therapy (REVERSAL) trial.

Journal: Circulation 20060620

Title: Incadronate inhibits aminopeptidase N expression in prostatic PC-3 cells.

Journal: Cancer letters 20060618

Title: Proteinuria, impaired kidney function, and adverse outcomes in people with coronary disease: analysis of a previously conducted randomised trial.

Journal: BMJ (Clinical research ed.) 20060617

Title: [High lowering of lipids can melt coronary plaques -- is coronary disease reversible?].

Journal: MMW Fortschritte der Medizin 20060615

Title: [For coronary disease patients is certain: the lower the LDL the better].

Journal: MMW Fortschritte der Medizin 20060615

Title: Intensive statin therapy and the risk of hospitalization for heart failure after an acute coronary syndrome in the PROVE IT-TIMI 22 study.

Journal: Journal of the American College of Cardiology 20060606

Title: N-3 fatty acid supplementation decreases plasma homocysteine in diabetic dyslipidemia treated with statin-fibrate combination.

Journal: The Journal of nutritional biochemistry 20060601

Title: ApoE plasma levels and risk of cardiovascular mortality in old age.

Journal: PLoS medicine 20060601

Title: Does random treatment assignment cause harm to research participants?

Journal: PLoS medicine 20060601

Title: Pharmacokinetics and response to pravastatin in paediatric patients with familial hypercholesterolaemia and in paediatric cardiac transplant recipients in relation to polymorphisms of the SLCO1B1 and ABCB1 genes.

Journal: British journal of clinical pharmacology 20060601

Title: Effects of obesity on lipid-lowering, anti-inflammatory, and antiatherosclerotic benefits of atorvastatin or pravastatin in patients with coronary artery disease (from the REVERSAL Study).

Journal: The American journal of cardiology 20060601

Title: Pravastatin improves remodeling and cardiac function after myocardial infarction by an antiinflammatory mechanism rather than by the induction of angiogenesis.

Journal: The Annals of thoracic surgery 20060601

Title: Invited commentary.

Journal: The Annals of thoracic surgery 20060601

Title: Differential effects of different statins on endothelin-1 gene expression and endothelial NOS phosphorylation in porcine aortic endothelial cells.

Journal: Experimental biology and medicine (Maywood, N.J.) 20060601

Title: Pravastatin, simvastatin, and atorvastatin appear equally effective for preventing cardiovascular events.

Journal: Evidence-based cardiovascular medicine 20060601

Title: Effects of preoperative statin therapy on cytokines after cardiac surgery.

Journal: The Thoracic and cardiovascular surgeon 20060601

Title: The clinical relevance of low-density-lipoproteins size modulation by statins.

Journal: Cardiovascular drugs and therapy 20060601

Title: Cost-effectiveness of cholesterol-lowering therapy with pravastatin in patients with previous acute coronary syndromes aged 65 to 74 years compared with younger patients: results from the LIPID study.

Journal: American heart journal 20060601

Title: Long-term safety and effectiveness of statins for heart transplant recipients in routine clinical practice.

Journal: Transplantation proceedings 20060601

Title: Statins: beneficial or adverse for glucose metabolism.

Journal: Journal of atherosclerosis and thrombosis 20060601

Title: Rosuvastatin 5 and 10 mg/d: a pilot study of the effects in hypercholesterolemic adults unable to tolerate other statins and reach LDL cholesterol goals with nonstatin lipid-lowering therapies.

Journal: Clinical therapeutics 20060601

Title: Apolipoprotein-E polymorphism and response to pravastatin in men with coronary artery disease (REGRESS).

Journal: Acta cardiologica 20060601

Title: [Myocardial dysfunction].

Journal: Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20060601

Title: Does pravastatin safely and effectively improve lipid profiles in children who have received a kidney transplant?

Journal: Nature clinical practice. Nephrology 20060601

Title: Lipoprotein-associated phospholipase A2, vascular inflammation and cardiovascular risk prediction.

Journal: Vascular health and risk management 20060601

Title: Plant sterols as dietary adjuvants in the reduction of cardiovascular risk: theory and evidence.

Journal: Vascular health and risk management 20060601

Title: Fenofibrate: a novel formulation (Triglide) in the treatment of lipid disorders: a review.

Journal: International journal of nanomedicine 20060601

Title: Statin use and breast cancer: prospective results from the Women's Health Initiative.

Journal: Journal of the National Cancer Institute 20060517

Title: Relationship between cardiovascular risk factors and atherosclerotic disease burden measured by intravascular ultrasound.

Journal: Journal of the American College of Cardiology 20060516

Title: [Therapeutic effects of pravastatin on colitis induced by acetic acid and relevant mechanism: experiment with rats].

Journal: Zhonghua yi xue za zhi 20060516

Title: Orange juice increased the bioavailability of pravastatin, 3-hydroxy-3-methylglutaryl CoA reductase inhibitor, in rats and healthy human subjects.

Journal: Life sciences 20060508

Title: Oxidized low-density lipoprotein in children with familial hypercholesterolemia and unaffected siblings: effect of pravastatin.

Journal: Journal of the American College of Cardiology 20060502

Title: Statins and stroke: current clinical practice.

Journal: Stroke 20060501

Title: The 3-hydroxy-3-methylglutaryl co-enzyme A reductase inhibitor pravastatin enhances neurite outgrowth in hippocampal neurons.

Journal: Journal of neurochemistry 20060501

Title: Effect of statins on platelet PAR-1 thrombin receptor in patients with the metabolic syndrome (from the PAR-1 inhibition by statins [PARIS] study).

Journal: The American journal of cardiology 20060501

Title: Involvement of 2-C-methyl-D-erythritol-4-phosphate pathway in biosynthesis of aphidicolin-like tetracyclic diterpene of Scoparia dulcis.

Journal: Chemical & pharmaceutical bulletin 20060501

Title: Impact of the SLCO1B1 polymorphism on the pharmacokinetics and lipid-lowering efficacy of multiple-dose pravastatin.

Journal: Clinical pharmacology and therapeutics 20060501

Title: Effects of organic anion transporting polypeptide 1B1 haplotype on pharmacokinetics of pravastatin, valsartan, and temocapril.

Journal: Clinical pharmacology and therapeutics 20060501

Title: A switch in time saves more than nine. Two popular statins, Pravachol and Zocor, go generic this summer, paving the way for significant savings.

Journal: Harvard heart letter : from Harvard Medical School 20060501

Title: Statins in patients with chronic kidney disease: evidence from systematic reviews and randomized clinical trials.

Journal: PLoS medicine 20060501

Title: Drug and medical cost effects of a drug formulary change with therapeutic interchange for statin drugs in a multistate managed Medicaid organization.

Journal: Journal of managed care pharmacy : JMCP 20060501

Title: [Statin therapy: cost-effectiveness and evaluation of evidence as criterium for improving expenditure within the National Health Program].

Journal: Recenti progressi in medicina 20060501

Title: Is atorvastatin superior to other statins? Analysis of the clinical trials with atorvastatin having cardiovascular endpoints.

Journal: Reviews on recent clinical trials 20060501

Title: Hydroxymethylglutaryl-coenzyme A reductase inhibitors induce apoptosis in human cardiac myocytes in vitro.

Journal: Biochemical pharmacology 20060428

Title: Effect of pravastatin on body composition and markers of cardiovascular disease in HIV-infected men--a randomized, placebo-controlled study.

Journal: AIDS (London, England) 20060424

Title: Statins in HIV-associated lipodystrophy and metabolic syndrome: is there a missing link?

Journal: AIDS (London, England) 20060424

Title: Statin safety: a systematic review.

Journal: The American journal of cardiology 20060417

Title: Effects of colesevelam hydrochloride on low-density lipoprotein cholesterol and high-sensitivity C-reactive protein when added to statins in patients with hypercholesterolemia.

Journal: The American journal of cardiology 20060415

Title: Lipoprotein-associated phospholipase A2 and its association with cardiovascular outcomes in patients with acute coronary syndromes in the PROVE IT-TIMI 22 (PRavastatin Or atorVastatin Evaluation and Infection Therapy-Thrombolysis In Myocardial Infarction) trial.

Journal: Circulation 20060411

Title: [Treatment of dyslipoproteinemia in chronic renal failure].

Journal: MMW Fortschritte der Medizin 20060406

Title: Effect of pravastatin, simvastatin and atorvastatin on the phagocytic activity of mouse peritoneal macrophages.

Journal: Experimental and molecular pathology 20060401

Title: Changes of plasma inflammatory markers after withdrawal of statin therapy in patients with hyperlipidemia.

Journal: Clinica chimica acta; international journal of clinical chemistry 20060401

Title: Pitavastatin effect on ATP binding cassette A1-mediated lipid efflux from macrophages: evidence for liver X receptor (LXR)-dependent and LXR-independent mechanisms of activation by cAMP.

Journal: The Journal of pharmacology and experimental therapeutics 20060401

Title: Progression of cerebral white matter lesions is not associated with development of depressive symptoms in elderly subjects at risk of cardiovascular disease: The PROSPER Study.

Journal: International journal of geriatric psychiatry 20060401

Title: Chronic kidney disease: a public health problem that needs a public health action plan.

Journal: Preventing chronic disease 20060401

Title: Effect of rosuvastatin compared with other statins on lipid levels and National Cholesterol Education Program goal attainment for low-density lipoprotein cholesterol in a usual care setting.

Journal: Pharmacotherapy 20060401

Title: Influence of the SLCO1B1*1b and *5 haplotypes on pravastatin's cholesterol lowering capabilities and basal sterol serum levels.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20060401

Title: [Statin treatment in patients with acute coronary syndrome].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20060401

Title: Drug utilization of ezetimibe in rehabilitation centres: registry analysis of factors influencing prescription and effectiveness of treatment.

Journal: Current medical research and opinion 20060401

Title: Influences of statins on glucose tolerance in patients with type 2 diabetes mellitus.

Journal: Journal of atherosclerosis and thrombosis 20060401

Title: Retrospective review of sex differences in the management of dyslipidemia in coronary heart disease: an analysis of patient data from a Maryland-based health maintenance organization.

Journal: Clinical therapeutics 20060401

Title: [Infiltrative lung disease with alveolar density on x-ray: observation].

Journal: Revue des maladies respiratoires 20060401

Title: Pharmacokinetic interaction between nelfinavir and pravastatin in HIV-seronegative volunteers: ACTG Study A5108.

Journal: AIDS (London, England) 20060321

Title: A tale of two trials: a comparison of the post-acute coronary syndrome lipid-lowering trials A to Z and PROVE IT-TIMI 22.

Journal: Circulation 20060321

Title: Direct comparison of the A to Z and PROVE IT trials: a second chance to gain a first impression.

Journal: Circulation 20060321

Title: Effect of statin treatment on coronary collateral development in patients with diabetes mellitus.

Journal: The American journal of cardiology 20060315

Title: Statins and nitric oxide reduce C-reactive protein production while inflammatory conditions persist.

Journal: Molecular immunology 20060301

Title: Analysis of five HMG-CoA reductase inhibitors-- atorvastatin, lovastatin, pravastatin, rosuvastatin and simvastatin: pharmacological, pharmacokinetic and analytical overview and development of a new method for use in pharmaceutical formulations analysis and in vitro metabolism studies.

Journal: Biomedical chromatography : BMC 20060301

Title: Brain cholesterol synthesis in mice is affected by high dose of simvastatin but not of pravastatin.

Journal: The Journal of pharmacology and experimental therapeutics 20060301

Title: Pravastatin inhibits expression of lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) in Watanabe heritable hyperlipidemic rabbits: a new pleiotropic effect of statins.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20060301

Title: Effects of acid and lactone forms of eight HMG-CoA reductase inhibitors on CYP-mediated metabolism and MDR1-mediated transport.

Journal: Pharmaceutical research 20060301

Title: HMG-CoA reductase inhibitors induce apoptosis in pericytes.

Journal: Microvascular research 20060301

Title: Effects of various statins on cytokine-dependent growth and IgE-dependent release of histamine in human mast cells.

Journal: Allergy 20060301

Title: Effect of cyclosporin A on the biliary excretion of cholephilic compounds in rats.

Journal: Hepatology research : the official journal of the Japan Society of Hepatology 20060301

Title: Evidence-based prescribing of statins: a developing world perspective.

Journal: PLoS medicine 20060301

Title: Low high-density lipoprotein cholesterol and cardiovascular disease: risk reduction with statin therapy.

Journal: American heart journal 20060301

Title: Increased inflammatory markers in children with familial hypercholesterolaemia.

Journal: European journal of clinical investigation 20060301

Title: Localized rhabdomyolysis after exertion in a cardiac transplant recipient on statin therapy.

Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20060301

Title: Rapid identification of three functionally relevant polymorphisms in the OATP1B1 transporter gene using Pyrosequencing.

Journal: Pharmacogenomics 20060301

Title: Hydroxymethylglutaryl-CoA reductase inhibitors in older persons with acute myocardial infarction: evidence for an age-statin interaction.

Journal: Journal of the American Geriatrics Society 20060301

Title: Statin-associated myasthenia gravis: report of 4 cases and review of the literature.

Journal: Medicine 20060301

Title: Processing of amyloid precursor protein as a biochemical link between atherosclerosis and Alzheimer's disease.

Journal: Cardiovascular & hematological disorders drug targets 20060301

Title: Cost-effectiveness of screening for albuminuria with subsequent fosinopril treatment to prevent cardiovascular events: A pharmacoeconomic analysis linked to the prevention of renal and vascular endstage disease (PREVEND) study and the prevention of renal and vascular endstage disease intervention trial (PREVEND IT).

Journal: Clinical therapeutics 20060301

Title: Treatment of hypercholesterolemia in patients with metabolic syndrome: how do different statins compare?

Journal: Nature clinical practice. Endocrinology & metabolism 20060301

Title: Treatment of severe sepsis: where next? Current and future treatment approaches after the introduction of drotrecogin alfa.

Journal: Vascular health and risk management 20060301

Title: Complementary therapy to target LDL cholesterol: the role of the ezetimibe/simvastatin combination.

Journal: Vascular health and risk management 20060301

Title: Evaluation of efficacy and safety of fixed dose lovastatin and niacin(ER) combination in asian Indian dyslipidemic patients: a multicentric study.

Journal: Vascular health and risk management 20060301

Title: Telithromycin in the treatment of acute bacterial sinusitis, acute exacerbations of chronic bronchitis, and community-acquired pneumonia.

Journal: Therapeutics and clinical risk management 20060301

Title: [Effect of pravastatin on cholesteryl esters in foam cells and the relation with caveolin-1].

Journal: Sheng li xue bao : [Acta physiologica Sinica] 20060225

Title: Formal enantioselective synthesis of (+)-compactin.

Journal: Organic letters 20060216

Title: Pravastatin increases survival and suppresses an increase in myocardial matrix metalloproteinase activity in a rat model of heart failure.

Journal: Cardiovascular research 20060215

Title: Statins induce calcium-dependent mitochondrial permeability transition.

Journal: Toxicology 20060215

Title: Improving effect of ethyl eicosapentanoate on statin-induced rhabdomyolysis in Eisai hyperbilirubinemic rats.

Journal: Biochemical and biophysical research communications 20060203

Title: The prion protein requires cholesterol for cell surface localization.

Journal: Molecular and cellular neurosciences 20060201

Title: Pharmacogenetics: progress, pitfalls and clinical potential for coronary heart disease.

Journal: Vascular pharmacology 20060201

Title: Is there an interaction between pravastatin and clinical events other than vasospasm in patients with aneurysmal subarachnoid hemorrhage?

Journal: Stroke 20060201

Title: Pravastatin-induced lichenoid drug eruption.

Journal: The Australasian journal of dermatology 20060201

Title: Activators of the energy sensing kinase AMPK inhibit random cell movement and chemotaxis in U937 cells.

Journal: Immunology and cell biology 20060201

Title: Increase in periventricular white matter hyperintensities parallels decline in mental processing speed in a non-demented elderly population.

Journal: Journal of neurology, neurosurgery, and psychiatry 20060201

Title: Use of hydroxy-methyl-glutaryl coenzyme A reductase inhibitors is associated with risk of lymphoid malignancies.

Journal: Cancer science 20060201

Title: Are statins created equal? Evidence from randomized trials of pravastatin, simvastatin, and atorvastatin for cardiovascular disease prevention.

Journal: American heart journal 20060201

Title: Apoptosis of rheumatoid synovial cells by statins through the blocking of protein geranylgeranylation: a potential therapeutic approach to rheumatoid arthritis.

Journal: Arthritis and rheumatism 20060201

Title: 'Anti-inflammatory' drugs and their effects on type 2 diabetes.

Journal: Diabetes technology & therapeutics 20060201

Title: Serum noncholesterol sterols in children with heterozygous familial hypercholesterolemia undergoing pravastatin therapy.

Journal: The Journal of pediatrics 20060201

Title: [Statins in patients with kidney failure: efficacy, tolerance, and prescription guidelines in patients with chronic kidney disease and renal transplant].

Journal: Presse medicale (Paris, France : 1983) 20060201

Title: Pravastatin attenuates tourniquet-induced skeletal muscle ischemia reperfusion injury.

Journal: Acta orthopaedica 20060201

Title: Letter regarding article by Tonelli et al, 'effect of pravastatin on rate of kidney function loss in people with or at risk for coronary disease'.

Journal: Circulation 20060131

Title: [Recurrent acute pancreatitis during pravastatin-therapy].

Journal: Praxis 20060125

Title: Comparison of effects of pravastatin and hormone therapy on soluble P-selectin and platelet P-selectin expression in postmenopausal hypercholesterolemic women.

Journal: Maturitas 20060120

Title: Alkylamines cause Vgamma9Vdelta2 T-cell activation and proliferation by inhibiting the mevalonate pathway.

Journal: Blood 20060115

Title: Cholecystokinin stimulates the recruitment of the Src-RhoA-phosphoinositide 3-kinase pathway by Vav-2 downstream of G(alpha13) in pancreatic acini.

Journal: Biochemical and biophysical research communications 20060106

Title: Statins for high-risk patients without heart disease or high cholesterol.

Journal: The Medical letter on drugs and therapeutics 20060102

Title: Effects of statins on endothelial function and lipid profile in HIV infected persons receiving protease inhibitor-containing anti-retroviral combination therapy: a randomised double blind crossover trial.

Journal: Heart (British Cardiac Society) 20060101

Title: Protective role of pravastatin in the pathogenesis of the metabolic syndrome.

Journal: Medical hypotheses 20060101

Title: HMG-CoA reductase inhibitors upregulate heme oxygenase-1 expression in murine RAW264.7 macrophages via ERK, p38 MAPK and protein kinase G pathways.

Journal: Cellular signalling 20060101

Title: Determinants of the differences in LDL-cholesterol after initiation of statin treatment.

Journal: The Annals of pharmacotherapy 20060101

Title: Effects of pravastatin on the in vitro phagocytic function and hydrogen peroxide production by monocytes of healthy individuals.

Journal: International immunopharmacology 20060101

Title: Electrochemical properties and square-wave voltammetric determination of pravastatin.

Journal: Analytical and bioanalytical chemistry 20060101

Title: A cost evaluation of the Georgia Stroke and Heart Attack Prevention Program.

Journal: Preventing chronic disease 20060101

Title: Preoperative statin therapy and troponin T predict early complications of coronary artery surgery.

Journal: The Annals of thoracic surgery 20060101

Title: Pharmacological strategies for the prevention of Alzheimer's disease.

Journal: Expert opinion on pharmacotherapy 20060101

Title: Effect of pravastatin on plasma sterols and oxysterols in men.

Journal: European journal of clinical pharmacology 20060101

Title: Statins and osteoporosis: new role for old drugs.

Journal: The Journal of pharmacy and pharmacology 20060101

Title: Plasma LDL and HDL characteristics and carotenoid content are positively influenced by egg consumption in an elderly population.

Journal: Nutrition & metabolism 20060101

Title: Statins decrease serotonin-induced contractions in coronary arteries of swine in vitro.

Journal: Pharmacology 20060101

Title: Ezetimibe for the treatment of uncontrolled hypercholesterolemia in patients with high-dose statin therapy after renal transplantation.

Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20060101

Title: Muscle symptoms associated with statins: a series of twenty patients.

Journal: Basic & clinical pharmacology & toxicology 20060101

Title: Time course of rapid C-reactive protein reduction by pravastatin in patients with stable angina.

Journal: Angiology 20060101

Title: Statin wars following coronary revascularization--evidence-based clinical practice?

Journal: The Canadian journal of cardiology 20060101

Title: C-reactive protein levels and outcomes after statin therapy.

Journal: Current atherosclerosis reports 20060101

Title: Pravastatin and clopidogrel combined inhibit intimal hyperplasia in a rat carotid endarterectomy model.

Journal: Vascular and endovascular surgery 20060101

Title: Effect of pravastatin and atorvastatin on glucose metabolism in nondiabetic patients with hypercholesterolemia.

Journal: Internal medicine (Tokyo, Japan) 20060101

Title: Statin-related adverse events: a meta-analysis.

Journal: Clinical therapeutics 20060101

Title: Endothelial dysfunction: a comprehensive appraisal.

Journal: Cardiovascular diabetology 20060101

Title: The statins: drug interactions of significance to the dental practitioner.

Journal: Dental update 20060101

Title: [Prevention of the manifestation of diabetes in the elderly in the presymptomatic stage].

Journal: Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics 20060101

Title: Who should receive statin therapy among the elderly?

Journal: The American journal of geriatric cardiology 20060101

Title: Circle of Willis variation in a complex stroke presentation: a case report.

Journal: BMC neurology 20060101

Title: Post-genomics of the model haloarchaeon Halobacterium sp. NRC-1.

Journal: Saline systems 20060101

Title: Comparative study on the bioequivalence of two formulations of pravastatin. Data from a crossover, randomised, open-label bioequivalence study in healthy volunteers.

Journal: Arzneimittel-Forschung 20060101

Title: Action of Lovastatin (Mevinolin) on an in vitro model of angiogenesis and its co-culture with malignant melanoma cell lines.

Journal: Cancer cell international 20060101

Title: Basilar artery dolichoectasia with partial thrombosis.

Journal: Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 20060101

Title: Effect of probucol on elderly hypercholesterolemic patients in the FAST study.

Journal: Fukuoka igaku zasshi = Hukuoka acta medica 20060101

Title: Revascularization and cardioprotective drug treatment in myocardial infarction patients: how do they impact on patients' survival when delivered as usual care.

Journal: BMC cardiovascular disorders 20060101

Title: The fading of reported effectiveness. A meta-analysis of randomised controlled trials.

Journal: BMC medical research methodology 20060101

Title: Prevention of positive coronary artery remodeling with statin therapy in patients with coronary artery diseases.

Journal: Angiology 20060101

Title: Biliary excretion of sulfated bile acids and organic anions in zone 1- and zone 3-injured rats.

Journal: Journal of gastroenterology and hepatology 20060101

Title: Vascular endothelial growth factor serum concentrations in hypercholesterolemic patients.

Journal: Scandinavian journal of clinical and laboratory investigation 20060101

Title: A randomized trial to assess the impact of opinion leader endorsed evidence summaries on the use of secondary prevention strategies in patients with coronary artery disease: the ESP-CAD trial protocol [NCT00175240].

Journal: Implementation science : IS 20060101

Title: Assessing health state utilities in elderly patients at cardiovascular risk.

Journal: Medical decision making : an international journal of the Society for Medical Decision Making 20060101

Title: Modular prevention of heart disease following acute coronary syndrome (ACS) [ISRCTN42984084].

Journal: BMC cardiovascular disorders 20060101

Title: Cost-effectiveness analysis of cholesterol-lowering therapies in Spain.

Journal: American journal of cardiovascular drugs : drugs, devices, and other interventions 20060101

Title: Comparison between mevinolin and PTH action on MG63 osteoblast-like cells.

Journal: Biomedical sciences instrumentation 20060101

Title: Gemcitabine in combination with EGF-Receptor antibody (Cetuximab) as a treatment of cholangiocarcinoma: a case report.

Journal: BMC cancer 20060101

Title: Haemostasis, inflammation and renal function following exercise in patients with intermittent claudication on statin and aspirin therapy.

Journal: Thrombosis journal 20060101

Title: Statin-induced expression of CD59 on vascular endothelium in hypoxia: a potential mechanism for the anti-inflammatory actions of statins in rheumatoid arthritis.

Journal: Arthritis research & therapy 20060101

Title: Inhibitory effect of statins on renal epithelial-to-mesenchymal transition.

Journal: American journal of nephrology 20060101

Title: Development and testing of innovative patient resources for the management of coronary heart disease (CHD): a descriptive study.

Journal: BMC health services research 20060101

Title: [Do statins have a place for cardiovascular prevention in elderly people?].

Journal: Revue medicale de Liege 20060101

Title: Pharmacogenetic determinants of variability in lipid-lowering response to pravastatin therapy.

Journal: Journal of human genetics 20060101

Title: Population variation and differences in serum leptin independent of adiposity: a comparison of Ache Amerindian men of Paraguay and lean American male distance runners.

Journal: Nutrition & metabolism 20060101

Title: Statins of different brain penetrability differentially affect CSF PLTP activity.

Journal: Dementia and geriatric cognitive disorders 20060101

Title: Roles of cholesterol and lipids in the etiopathogenesis of Alzheimer's disease.

Journal: Journal of biomedicine & biotechnology 20060101

Title: Changes in practice patterns affecting in-hospital and post-discharge survival among ACS patients.

Journal: BMC health services research 20060101

Title: Lipid lowering therapy in the elderly: is there a benefit?

Journal: Current pharmaceutical design 20060101

Title: Autosomal recessive cerebellar ataxias.

Journal: Orphanet journal of rare diseases 20060101

Title: Effects of pravastatin treatment on blood pressure regulation after renal transplantation.

Journal: Kidney & blood pressure research 20060101

Title: Drug-herb interactions: eliminating toxicity with hard drug design.

Journal: Current pharmaceutical design 20060101

Title: A systems biology strategy reveals biological pathways and plasma biomarker candidates for potentially toxic statin-induced changes in muscle.

Journal: PloS one 20060101

Title: Comparison of the efficacy and safety of rosuvastatin 10 mg and atorvastatin 20 mg in high-risk patients with hypercholesterolemia--Prospective study to evaluate the Use of Low doses of the Statins Atorvastatin and Rosuvastatin (PULSAR).

Journal: Trials 20060101

Title: Effect of olmesartan medoxomil on atherosclerosis: clinical implications of the emerging evidence.

Journal: American journal of cardiovascular drugs : drugs, devices, and other interventions 20060101

Title: [C-reactive protein in cardiovascular diseases].

Journal: Przeglad lekarski 20060101

Title: Generic pravastatin approved.

Journal: FDA consumer 20060101

Title: Chinese red yeast rice (Monascus purpureus) for primary hyperlipidemia: a meta-analysis of randomized controlled trials.

Journal: Chinese medicine 20060101

Title: Changes in cholesterol metabolism are associated with PS1 and PS2 gene regulation in SK-N-BE.

Journal: Journal of molecular neuroscience : MN 20060101

Title: [The effect of statins on lipids peroxidation and activities of antioxidants enzymes in patients with dyslipidemia].

Journal: Przeglad lekarski 20060101

Title: Lipid-modifying and pleiotropic effects of gemfibrozil, simvastatin and pravastatin in patients with dyslipidemia.

Journal: Folia medica 20060101

Title: Serum lipid profile constituents as markers of cardiovascular morbidity in patients on chronic hemodialysis.

Journal: Biomarker insights 20060101

Title: Effect of atorvastatin (80 mg/day) versus pravastatin (40 mg/day) on arterial remodeling at coronary branch points (from the REVERSAL study).

Journal: The American journal of cardiology 20051215

Title: Stabilization of carotid atheroma assessed by quantitative ultrasound analysis in nonhypercholesterolemic patients with coronary artery disease.

Journal: Journal of the American College of Cardiology 20051206

Title: Statins prevent beta-amyloid inhibition of sympathetic alpha7-nAChR-mediated nitrergic neurogenic dilation in porcine basilar arteries.

Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20051201

Title: Effect of pravastatin in people with diabetes and chronic kidney disease.

Journal: Journal of the American Society of Nephrology : JASN 20051201

Title: Prospective monitoring of lipid profiles in children receiving pravastatin preemptively after renal transplantation.

Journal: Pediatric transplantation 20051201

Title: Underutilization of aspirin persists in US ambulatory care for the secondary and primary prevention of cardiovascular disease.

Journal: PLoS medicine 20051201

Title: Effect of statin use in patients with acute coronary syndromes and a serum low-density lipoprotein<or=80 mg/dl.

Journal: The American journal of cardiology 20051201

Title: Antihyperlipidaemic effect of a Monascus purpureus brand dietary supplement on a large sample of subjects at low risk for cardiovascular disease: a pilot study.

Journal: Complementary therapies in medicine 20051201

Title: Does pravastatin increase chylomicron remnant catabolism in postmenopausal women with type 2 diabetes mellitus?

Journal: Clinical endocrinology 20051201

Title: Achieving lipid goals in real life: the Dutch DISCOVERY study.

Journal: International journal of clinical practice 20051201

Title: Halting the progression of atherosclerosis with intensive lipid lowering: results from the Reversal of Atherosclerosis with Aggressive Lipid Lowering (REVERSAL) trial.

Journal: The American journal of medicine 20051201

Title: Improved outcome after acute coronary syndromes with an intensive versus standard lipid-lowering regimen: results from the Pravastatin or Atorvastatin Evaluation and Infection Therapy-Thrombolysis in Myocardial Infarction 22 (PROVE IT-TIMI 22) trial.

Journal: The American journal of medicine 20051201

Title: What impact will current trial data have on future guideline recommendations?

Journal: The American journal of medicine 20051201

Title: The ability of statins to protect low density lipoprotein from oxidation in hypercholesterolemic patients.

Journal: International journal of clinical pharmacology and therapeutics 20051201

Title: [Fluvastatin-induced dermatomyositis].

Journal: Annales de dermatologie et de venereologie 20051201

Title: Renoprotective effect of pravastatin in salt-loaded Dahl salt-sensitive rats.

Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20051201

Title: Optimal lipid modification: the rationale for combination therapy.

Journal: Vascular health and risk management 20051201

Title: Efficacy and safety of atorvastatin in South Asian patients with dyslipidemia: an open label noncomparative pilot study.

Journal: Vascular health and risk management 20051201

Title: Are statins being underdosed in clinical practice? Data from TACTICS-TIMI 18.

Journal: Critical pathways in cardiology 20051201

Title: [Significance of cholesterol levels in patients 75 years or older].

Journal: Presse medicale (Paris, France : 1983) 20051119

Title: Plasma lipoproteins and apolipoproteins as predictors of cardiovascular risk and treatment benefit in the PROspective Study of Pravastatin in the Elderly at Risk (PROSPER).

Journal: Circulation 20051115

Title: Low-density lipoprotein receptor genotype and response to pravastatin in children with familial hypercholesterolemia: substudy of an intima-media thickness trial.

Journal: Circulation 20051115

Title: [How can lipid therapy be improved? Cardiologists insist on dual cholesterol inhibition].

Journal: MMW Fortschritte der Medizin 20051110

Title: The effect of six different statins on the proliferation, migration, and invasion of human smooth muscle cells.

Journal: The Journal of surgical research 20051101

Title: The effect of pravastatin on intima media thickness of the carotid artery in patients with normal cholesterol.

Journal: European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery 20051101

Title: Disposition of oral and intravenous pravastatin in MRP2-deficient TR- rats.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20051101

Title: [Pravastatin-induced dermatomyositis].

Journal: La Revue de medecine interne 20051101

Title: Systemic inflammatory markers in acute coronary syndrome: association with cardiovascular risk factors and effect of early lipid lowering.

Journal: Coronary artery disease 20051101

Title: Optimal goals for statin use in patients with coronary artery disease.

Journal: Current opinion in cardiology 20051101

Title: Evaluation of the paraoxonases as candidate genes for stroke: Gln192Arg polymorphism in the paraoxonase 1 gene is associated with increased risk of stroke.

Journal: Stroke 20051101

Title: A novel nitric oxide-releasing statin derivative exerts an antiplatelet/antithrombotic activity and inhibits tissue factor expression.

Journal: Journal of thrombosis and haemostasis : JTH 20051101

Title: Intensity of lipid lowering with statins and brachial artery vascular endothelium reactivity after acute coronary syndromes (from the BRAVER trial).

Journal: The American journal of cardiology 20051101

Title: X-Hitting: an algorithm for novelty detection and dereplication by UV spectra of complex mixtures of natural products.

Journal: Analytical chemistry 20051101

Title: Statin-induced apoptosis linked with membrane farnesylated Ras small G protein depletion, rather than geranylated Rho protein.

Journal: The Journal of pharmacy and pharmacology 20051101

Title: Rescue of heterochromatin organization in Hutchinson-Gilford progeria by drug treatment.

Journal: Cellular and molecular life sciences : CMLS 20051101

Title: Myonecrosis after elective percutaneous coronary intervention: effect of clopidogrel-statin interaction.

Journal: The Journal of invasive cardiology 20051101

Title: The effect of switching on compliance and persistence: the case of statin treatment.

Journal: The American journal of managed care 20051101

Title: HMG-CoA reductase inhibitors do not improve glucose intolerance in spontaneously diabetic Goto-Kakizaki rats.

Journal: Biological & pharmaceutical bulletin 20051101

Title: Differential associations of statin and fibrate treatment with carotid arterial remodeling.

Journal: American journal of hypertension 20051101

Title: Ten-year follow-up of a randomized trial of pravastatin in heart transplant patients.

Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20051101

Title: In-hospital initiation of statin therapy in acute coronary syndromes: maximizing the early and long-term benefits.

Journal: Chest 20051101

Title: Pravastatin reduces thrombogenicity by mechanisms beyond plasma cholesterol lowering.

Journal: Thrombosis and haemostasis 20051101

Title: Safety of statins when response is carefully monitored: a study of 336 heart recipients.

Journal: Transplantation proceedings 20051101

Title: The benefits of statin therapy--what questions remain?

Journal: Clinical cardiology 20051101

Title: Relation between serum phosphate level and cardiovascular event rate in people with coronary disease.

Journal: Circulation 20051025

Title: Pravastatin suppresses the increase in matrix metalloproteinase-2 levels after acute myocardial infarction.

Journal: International journal of cardiology 20051020

Title: Early and late benefits of high-dose atorvastatin in patients with acute coronary syndromes: results from the PROVE IT-TIMI 22 trial.

Journal: Journal of the American College of Cardiology 20051018

Title: Can low-density lipoprotein be too low? The safety and efficacy of achieving very low low-density lipoprotein with intensive statin therapy: a PROVE IT-TIMI 22 substudy.

Journal: Journal of the American College of Cardiology 20051018

Title: Relationship between uncontrolled risk factors and C-reactive protein levels in patients receiving standard or intensive statin therapy for acute coronary syndromes in the PROVE IT-TIMI 22 trial.

Journal: Journal of the American College of Cardiology 20051018

Title: The potential relevance of the multiple lipid-independent (pleiotropic) effects of statins in the management of acute coronary syndromes.

Journal: Journal of the American College of Cardiology 20051018

Title: Barriers to a trial of atherosclerosis prevention in systemic lupus erythematosus.

Journal: Arthritis and rheumatism 20051015

Title: Effect of pravastatin on malondialdehyde-modified low-density lipoprotein levels and coronary plaque regression as determined by three-dimensional intravascular ultrasound.

Journal: The American journal of cardiology 20051015

Title: Beneficial effects of atorvastatin on sd LDL and LDL phenotype B in statin-naive patients and patients previously treated with simvastatin or pravastatin.

Journal: International journal of cardiology 20051010

Title: Pravastatin activates platelet nitric oxide synthase (NOS) in patients with type 2 diabetes mellitus and NOS activation is accompanied by serine phosphorylation.

Journal: Chinese medical journal 20051005

Title: The forgotten majority: unfinished business in cardiovascular risk reduction.

Journal: Journal of the American College of Cardiology 20051004

Title: Cholesterol biosynthesis and the pro-apoptotic effects of the p75 nerve growth factor receptor in PC12 pheochromocytoma cells.

Journal: Brain research. Molecular brain research 20051003

Title: In vitro effect of statins on cytokine production and mitogen response of human peripheral blood mononuclear cells.

Journal: Clinical immunology (Orlando, Fla.) 20051001

Title: Short-term reduction in bone markers with high-dose simvastatin.

Journal: Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 20051001

Title: Persistence and determinants of statin therapy among middle-aged patients free of cardiovascular disease.

Journal: European journal of clinical pharmacology 20051001

Title: Effect of combined treatment with an angiotensin II receptor antagonist and an HMG-CoA reductase inhibitor on atherosclerosis in genetically hyperlipidemic rabbits.

Journal: Journal of cardiovascular pharmacology 20051001

Title: Achievement of English National Service Framework lipid-lowering goals: pooled data from recent comparative treatment trials of statins at starting doses.

Journal: International journal of clinical practice 20051001

Title: Apical/basolateral surface expression of drug transporters and its role in vectorial drug transport.

Journal: Pharmaceutical research 20051001

Title: Effect of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors on high-sensitivity C-reactive protein levels.

Journal: Pharmacotherapy 20051001

Title: Hydrophilic statin suppresses vein graft intimal hyperplasia via endothelial cell-tropic Rho-kinase inhibition.

Journal: Journal of vascular surgery 20051001

Title: Different effect of statins on platelet oxidized-LDL receptor (CD36 and LOX-1) expression in hypercholesterolemic subjects.

Journal: Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis 20051001

Title: Statins modulate the levels of osteoprotegerin/receptor activator of NFkappaB ligand mRNA in mouse bone-cell cultures.

Journal: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20051001

Title: The long-term course of low-density lipoprotein cholesterol after initiation of statin treatment: retrospective database analysis over 3 years in health maintenance organization enrollees.

Journal: Clinical therapeutics 20051001

Title: [Hypolipidemic treatment under special conditions: posttransplant and/or immunosuppressive therapy].

Journal: Arquivos brasileiros de cardiologia 20051001

Title: [Hypolipidemic therapy under special conditions: acquired immune deficiency syndrome].

Journal: Arquivos brasileiros de cardiologia 20051001

Title: Cost-effectiveness of pravastatin for primary prevention of coronary artery disease in Japan.

Journal: International journal of cardiology 20050930

Title: Evaluation of apoptosis and necrosis induced by statins using fluorescence-enhanced flow cytometry.

Journal: Journal of pharmaceutical and biomedical analysis 20050915

Title: Structural insights into drug processing by human carboxylesterase 1: tamoxifen, mevastatin, and inhibition by benzil.

Journal: Journal of molecular biology 20050909

Title: Binding thermodynamics of statins to HMG-CoA reductase.

Journal: Biochemistry 20050906

Title: Review of primary and secondary prevention trials with lovastatin, pravastatin, and simvastatin.

Journal: The American journal of cardiology 20050905

Title: The case for intensive statin therapy after acute coronary syndromes.

Journal: The American journal of cardiology 20050905

Title: Early time to benefit with intensive statin treatment: could it be the pleiotropic effects?

Journal: The American journal of cardiology 20050905

Title: Effect of intensive lipid lowering on progression of coronary atherosclerosis: evidence for an early benefit from the Reversal of Atherosclerosis with Aggressive Lipid Lowering (REVERSAL) trial.

Journal: The American journal of cardiology 20050905

Title: Identification of the hepatic efflux transporters of organic anions using double-transfected Madin-Darby canine kidney II cells expressing human organic anion-transporting polypeptide 1B1 (OATP1B1)/multidrug resistance-associated protein 2, OATP1B1/multidrug resistance 1, and OATP1B1/breast cancer resistance protein.

Journal: The Journal of pharmacology and experimental therapeutics 20050901

Title: Involvement of BCRP (ABCG2) in the biliary excretion of pitavastatin.

Journal: Molecular pharmacology 20050901

Title: The effect of statin therapy on lipoprotein associated phospholipase A2 levels.

Journal: Atherosclerosis 20050901

Title: Statin-macrolide interaction risk: a population-based study throughout a general practice database.

Journal: European journal of clinical pharmacology 20050901

Title: Does statin monotherapy address the multiple lipid abnormalities in type 2 diabetes?

Journal: Atherosclerosis. Supplements 20050901

Title: Combined therapy with atorvastatin and calcineurin inhibitors: no interactions with tacrolimus.

Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20050901

Title: REVERSAL and PROVE-IT: are clinically oriented trials really better than 'pure' scientific studies?

Journal: International journal of cardiology 20050901

Title: The -514C/T polymorphism of the hepatic lipase gene significantly modulates the HDL-cholesterol response to statin treatment.

Journal: Atherosclerosis 20050901

Title: Lowering of elevated ambulatory blood pressure by HMG-CoA reductase inhibitors.

Journal: Journal of cardiovascular pharmacology 20050901

Title: The pharmacological potential of mushrooms.

Journal: Evidence-based complementary and alternative medicine : eCAM 20050901

Title: Survival, graft atherosclerosis, and rejection incidence in heart transplant recipients treated with statins: 5-year follow-up.

Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20050901

Title: [HIV infection, antiretroviral therapy, and endothelium].

Journal: Herz 20050901

Title: Lipid-modifying therapy and attainment of cholesterol goals in Europe: the Return on Expenditure Achieved for Lipid Therapy (REALITY) study.

Journal: Current medical research and opinion 20050901

Title: Differences between statins on clinical endpoints: a population-based cohort study.

Journal: Current medical research and opinion 20050901

Title: The prevention of type 2 diabetes: what is the evidence?

Journal: Minerva endocrinologica 20050901

Title: A randomized trial of the efficacy and safety of fenofibrate versus pravastatin in HIV-infected subjects with lipid abnormalities: AIDS Clinical Trials Group Study 5087.

Journal: AIDS research and human retroviruses 20050901

Title: Stroke prevention, blood cholesterol and statins.

Journal: Acta neurologica Taiwanica 20050901

Title: A case of familial hypercholesterolemia; secession from LDL-apheresis by the drug treatment with potent statin and resin.

Journal: The Tokai journal of experimental and clinical medicine 20050901

Title: Increase in plasma malondialdehyde-modified low-density lipoprotein in patients with atherothrombotic cerebral infarction.

Journal: The Tokai journal of experimental and clinical medicine 20050901

Title: [The effects of pravastatin on platelet-derived nitric oxide system in rabbits].

Journal: Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20050901

Title: Endothelial dysfunction: cardiovascular risk factors, therapy, and outcome.

Journal: Vascular health and risk management 20050901

Title: Actions of calcium channel blockers on vascular proteoglycan synthesis: relationship to atherosclerosis.

Journal: Vascular health and risk management 20050901

Title: Premature coronary artery disease in Indians and its associated risk factors.

Journal: Vascular health and risk management 20050901

Title: Impact of the pravastatin or atorvastatin evaluation and infection therapy-thrombolysis in myocardial infarction 22/Reversal of Atherosclerosis with Aggressive Lipid Lowering trials on trends in intensive versus moderate statin therapy in Ontario, Canada.

Journal: Circulation 20050830

Title: Rationale for new American Diabetes Association Guidelines: are national cholesterol education program goals adequate for the patient with diabetes mellitus?

Journal: The American journal of cardiology 20050822

Title: [Intensive LDL lowering to under 80 mg/dl: hypercholesteremia patients with stable coronary disease and diabetes profit especially significantly].

Journal: MMW Fortschritte der Medizin 20050818

Title: Effect of statins on the proteasomal activity in mammalian endothelial and vascular smooth muscle cells.

Journal: Biochemical pharmacology 20050815

Title: Fluvastatin synergistically enhances the antiproliferative effect of gemcitabine in human pancreatic cancer MIAPaCa-2 cells.

Journal: British journal of cancer 20050808

Title: Fast analysis of pravastatin in production media.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050805

Title: Functional involvement of rat organic anion transporter 2 (Slc22a7) in the hepatic uptake of the nonsteroidal anti-inflammatory drug ketoprofen.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20050801

Title: Bile salt export pump (BSEP/ABCB11) can transport a nonbile acid substrate, pravastatin.

Journal: The Journal of pharmacology and experimental therapeutics 20050801

Title: Hydroxymethylglutaryl co-enzyme A reductase inhibition attenuates endotoxin-mediated inflammatory responses.

Journal: The British journal of surgery 20050801

Title: Comparison of the effects of pravastatin and atorvastatin on fracture incidence in the PROVE IT-TIMI 22 trial--secondary analysis of a randomized controlled trial.

Journal: Bone 20050801

Title: Genomic effect of vitamin 'C' and statins within human mononuclear cells involved in atherogenic process.

Journal: European journal of clinical nutrition 20050801

Title: Comparison of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors (statins) as inhibitors of cytochrome P450 2C8.

Journal: Basic & clinical pharmacology & toxicology 20050801

Title: Add-on and withdrawal effect of pravastatin on proteinuria in hypertensive patients treated with AT receptor blockers.

Journal: Kidney international 20050801

Title: The effects of multiple doses of fenofibrate on the pharmacokinetics of pravastatin and its 3alpha-hydroxy isomeric metabolite.

Journal: Journal of clinical pharmacology 20050801

Title: Suppression of Wolffia arrhiza growth by brassinazole, an inhibitor of brassinosteroid biosynthesis and its restoration by endogenous 24-epibrassinolide.

Journal: Phytochemistry 20050801

Title: Three-year follow-up results of angiographic intervention trial using an HMG-CoA reductase inhibitor to evaluate retardation of obstructive multiple atheroma (ATHEROMA) study.

Journal: Circulation journal : official journal of the Japanese Circulation Society 20050801

Title: Statin use after acute myocardial infarction: a nationwide study in Denmark.

Journal: British journal of clinical pharmacology 20050801

Title: Induction of CTGF by TGF-beta1 in normal and radiation enteritis human smooth muscle cells: Smad/Rho balance and therapeutic perspectives.

Journal: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20050801

Title: Effects of acute treatment with pravastatin on cerebral vasospasm, autoregulation, and delayed ischemic deficits after aneurysmal subarachnoid hemorrhage: a phase II randomized placebo-controlled trial.

Journal: Stroke 20050801

Title: Lack of effect of pravastatin on cerebral blood flow or parenchymal volume loss in elderly at risk for vascular disease.

Journal: Stroke 20050801

Title: Treatment strategies in endothelial dysfunction: physical exercise versus pharmacological therapy.

Journal: European journal of cardiovascular prevention and rehabilitation : official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology 20050801

Title: Effect of mild endurance exercise training and pravastatin on peripheral vasodilatation of forearm resistance vessels in patients with coronary artery disease.

Journal: European journal of cardiovascular prevention and rehabilitation : official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology 20050801

Title: Relating statin therapy to C-reactive protein levels.

Journal: Expert opinion on pharmacotherapy 20050801

Title: Not all statins interfere with clopidogrel during antiplatelet therapy.

Journal: European journal of clinical investigation 20050801

Title: Effect of short-term treatment with pravastatin on cytokines and cytokine receptors in patients with chronic heart failure due to ischemic and nonischemic disease.

Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20050801

Title: Statins and cancer development.

Journal: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20050801

Title: The antiplatelet effect of clopidogrel is not attenuated by statin treatment in stable patients with ischemic heart disease.

Journal: Thrombosis and haemostasis 20050801

Title: New light on statin side effects. What recent research on the cholesterol drugs means to you.

Journal: Heart advisor 20050801

Title: Aggressive versus moderate lipid-lowering therapy in hypercholesterolemic postmenopausal women: Beyond Endorsed Lipid Lowering with EBT Scanning (BELLES).

Journal: Circulation 20050726

Title: Association between short-term effectiveness of statins and long-term adherence to lipid-lowering therapy.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20050715

Title: Effect of pravastatin on rate of kidney function loss in people with or at risk for coronary disease.

Journal: Circulation 20050712

Title: Intensive lipid lowering with atorvastatin in coronary disease.

Journal: The New England journal of medicine 20050707

Title: Statin treatment after onset of sepsis in a murine model improves survival.

Journal: Circulation 20050705

Title: Induction of macrophage elastase (MMP-12) gene expression by statins.

Journal: Journal of cellular physiology 20050701

Title: Effect of pravastatin on development of left ventricular hypertrophy in spontaneously hypertensive rats.

Journal: American journal of physiology. Heart and circulatory physiology 20050701

Title: Identification of HMG-CoA reductase inhibitors as activators for human, mouse and rat constitutive androstane receptor.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20050701

Title: Impact of statins in microalbuminuric subjects with the metabolic syndrome: a substudy of the PREVEND Intervention Trial.

Journal: European heart journal 20050701

Title: Metabolic syndrome criteria: ready for clinical prime time or work in progress?

Journal: European heart journal 20050701

Title: Statins prevent oxidized LDL-induced injury of glomerular podocytes by activating the phosphatidylinositol 3-kinase/AKT-signaling pathway.

Journal: Journal of the American Society of Nephrology : JASN 20050701

Title: D-4F and statins synergize to render HDL antiinflammatory in mice and monkeys and cause lesion regression in old apolipoprotein E-null mice.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20050701

Title: TaqIB polymorphism in CETP gene: the influence on incidence of cardiovascular disease in statin-treated patients with familial hypercholesterolemia.

Journal: European journal of human genetics : EJHG 20050701

Title: Improved cerebral vasoreactivity after statin administration in healthy adults.

Journal: Journal of neuroimaging : official journal of the American Society of Neuroimaging 20050701

Title: Biomarkers of inflammation and progression of chronic kidney disease.

Journal: Kidney international 20050701

Title: Comparison of rosuvastatin with atorvastatin, simvastatin and pravastatin in achieving cholesterol goals and improving plasma lipids in hypercholesterolaemic patients with or without the metabolic syndrome in the MERCURY I trial.

Journal: Diabetes, obesity & metabolism 20050701

Title: Biliary excretion of taurocholate, organic anions and vinblastine in rats with alpha-naphthylisothiocyanate-induced cholestasis.

Journal: Journal of gastroenterology and hepatology 20050701

Title: Substitution of nevirapine or efavirenz for protease inhibitor versus lipid-lowering therapy for the management of dyslipidaemia.

Journal: AIDS (London, England) 20050701

Title: Pravastatin does not have a consistent antiviral effect in chronically HIV-infected individuals on antiretroviral therapy.

Journal: AIDS (London, England) 20050701

Title: Suboptimal choices and dosing of statins at start of therapy.

Journal: British journal of clinical pharmacology 20050701

Title: Cholesterol levels and statin use in patients with coronary heart disease treated in primary care settings.

Journal: Preventing chronic disease 20050701

Title: Functional characterization of SLCO1B1 (OATP-C) variants, SLCO1B1*5, SLCO1B1*15 and SLCO1B1*15+C1007G, by using transient expression systems of HeLa and HEK293 cells.

Journal: Pharmacogenetics and genomics 20050701

Title: Effects of cholesterol-lowering statins on the aqueous humor outflow pathway.

Journal: Investigative ophthalmology & visual science 20050701

Title: Effect of efavirenz on the pharmacokinetics of simvastatin, atorvastatin, and pravastatin: results of AIDS Clinical Trials Group 5108 Study.

Journal: Journal of acquired immune deficiency syndromes (1999) 20050701

Title: Pravastatin does not affect insulin sensitivity and adipocytokines levels in healthy nondiabetic patients.

Journal: Metabolism: clinical and experimental 20050701

Title: In vivo and in vitro effects of statins on lymphocytes in patients with Hashimoto's thyroiditis.

Journal: European journal of endocrinology 20050701

Title: Rosuvastatin for the treatment of hypercholesterolemia.

Journal: Pharmacotherapy 20050701

Title: JBMR anniversary classic. Nitrogen-containing biophosphonates inhibit the mevalonate pathway and prevent post-translational prenylation of GTP-binding proteins, including Ras. Originally published in Volume 7, number 4, pp 581-9 (1998).

Journal: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20050701

Title: Volumetric quantitative analysis of tissue characteristics of coronary plaques after statin therapy using three-dimensional integrated backscatter intravascular ultrasound.

Journal: Journal of the American College of Cardiology 20050621

Title: Combined effects of losartan and pravastatin on interstitial inflammation and fibrosis in chronic cyclosporine-induced nephropathy.

Journal: Transplantation 20050615

Title: The safety of rosuvastatin as used in common clinical practice: a postmarketing analysis.

Journal: Circulation 20050614

Title: Genetic variation in the rate-limiting enzyme in cholesterol catabolism (cholesterol 7alpha-hydroxylase) influences the progression of atherosclerosis and risk of new clinical events.

Journal: Clinical science (London, England : 1979) 20050601

Title: Statins reduce interleukin-6-induced C-reactive protein in human hepatocytes: new evidence for direct antiinflammatory effects of statins.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20050601

Title: Pravastatin restores DDAH activity and endothelium-dependent relaxation of rat aorta after exposure to glycated protein.

Journal: Journal of cardiovascular pharmacology 20050601

Title: Cost effectiveness of rosuvastatin in treating patients to low-density lipoprotein cholesterol goals compared with atorvastatin, pravastatin, and simvastatin (a US Analysis of the STELLAR Trial).

Journal: The American journal of cardiology 20050601

Title: Plasma lipoprotein(a) [Lp(a)] concentrations and cardiovascular events in the elderly: evidence from the prospective study of pravastatin in the elderly at risk (PROSPER).

Journal: Atherosclerosis 20050601

Title: Effect of pravastatin on progression of coronary atherosclerosis in patients after coronary artery bypass surgery.

Journal: Circulation journal : official journal of the Japanese Circulation Society 20050601

Title: Baseline levels of low-density lipoprotein cholesterol and lipoprotein (a) and the AvaII polymorphism of the low-density lipoprotein receptor gene influence the response of low-density lipoprotein cholesterol to pravastatin treatment.

Journal: Metabolism: clinical and experimental 20050601

Title: Pravastatin reduces fibrinogen receptor gpIIIa on platelet-derived microparticles in patients with type 2 diabetes.

Journal: Journal of thrombosis and haemostasis : JTH 20050601

Title: Cardiovascular risk: prevention and treatment of the metabolic syndrome.

Journal: Diabetes research and clinical practice 20050601

Title: HDL-C and the diabetic patient: target for therapeutic intervention?

Journal: Diabetes research and clinical practice 20050601

Title: The effect of simvastatin on the proliferation and differentiation of human bone marrow stromal cells.

Journal: Journal of Korean medical science 20050601

Title: Can type 2 diabetes mellitus be considered preventable?

Journal: Diabetes research and clinical practice 20050601

Title: Atorvastatin.

Journal: Expert opinion on pharmacotherapy 20050601

Title: Prediction of genotoxicity of chemical compounds by statistical learning methods.

Journal: Chemical research in toxicology 20050601

Title: Early effects of statin therapy on endothelial function and microvascular reactivity in patients with coronary artery disease.

Journal: American heart journal 20050601

Title: Induction of micronuclei in CHO cells by bleomycin but not by X-irradiation is decreased by treatment with HMG-CoA reductase inhibitors.

Journal: Journal of radiation research 20050601

Title: Acute onset and worsening of diabetes concurrent with administration of statins.

Journal: Endocrine journal 20050601

Title: Gateways to clinical trials.

Journal: Methods and findings in experimental and clinical pharmacology 20050601

Title: 4,8-Dimethyldecanal, the aggregation pheromone of Tribolium castaneum, is biosynthesized through the fatty acid pathway.

Journal: Journal of chemical ecology 20050601

Title: [Erythrocyte fluidity in patients with hyperlipidemia during statins therapy].

Journal: Polskie Archiwum Medycyny Wewnetrznej 20050601

Title: A new paradigm of cardiovascular risk factor modification.

Journal: Vascular health and risk management 20050601

Title: Carotid ultrasound assessment of patients with coronary artery disease: a useful index for risk stratification.

Journal: Vascular health and risk management 20050601

Title: Treatment of high blood pressure and gain in event-free life expectancy.

Journal: Vascular health and risk management 20050601

Title: Clinical implications of changes in hepatic drug metabolism in older people.

Journal: Therapeutics and clinical risk management 20050601

Title: Effect of pravastatin on cerebral infarcts and white matter lesions.

Journal: Neurology 20050524

Title: Relative efficacy of atorvastatin 80 mg and pravastatin 40 mg in achieving the dual goals of low-density lipoprotein cholesterol <70 mg/dl and C-reactive protein <2 mg/l: an analysis of the PROVE-IT TIMI-22 trial.

Journal: Journal of the American College of Cardiology 20050517

Title: Efficacy and safety of rosuvastatin in treatment of dyslipidemia.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20050515

Title: Modulation of regulatory factors involved in cholesterol metabolism in response to feeding of pravastatin- or cholesterol-supplemented diet in chickens.

Journal: Biochimica et biophysica acta 20050515

Title: Statins' dosage in patients with renal failure and cyclosporine drug-drug interactions in transplant recipient patients.

Journal: International journal of cardiology 20050511

Title: Rapid effect of pravastatin on endothelial function and lipid peroxidation in unstable angina.

Journal: International journal of cardiology 20050511

Title: HMG CoA reductase inhibitors (statins) to treat Epstein-Barr virus-driven lymphoma.

Journal: British journal of cancer 20050509

Title: Uptake of irinotecan metabolite SN-38 by the human intestinal cell line Caco-2.

Journal: Cancer chemotherapy and pharmacology 20050501

Title: Statins activate the mitochondrial pathway of apoptosis in human lymphoblasts and myeloma cells.

Journal: Carcinogenesis 20050501

Title: Interleukin-6 and mevastatin regulate plasminogen activator inhibitor-1 through CCAAT/enhancer-binding protein-delta.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20050501

Title: Pharmacogenetic study of statin therapy and cholesterol reduction.

Journal: Current atherosclerosis reports 20050501

Title: Cholesteryl ester transfer protein TaqIB polymorphism in the cholesterol and recurrent events study.

Journal: Current atherosclerosis reports 20050501

Title: Effects of atorvastatin versus other statins on fasting and postprandial C-reactive protein and lipoprotein-associated phospholipase A2 in patients with coronary heart disease versus control subjects.

Journal: The American journal of cardiology 20050501

Title: Effectiveness of inhibition of cholesteryl ester transfer protein by JTT-705 in combination with pravastatin in type II dyslipidemia.

Journal: The American journal of cardiology 20050501

Title: Pravastatin limits endothelial activation after irradiation and decreases the resulting inflammatory and thrombotic responses.

Journal: Radiation research 20050501

Title: Biliary excretion of olmesartan, an anigotensin II receptor antagonist, in the rat.

Journal: Journal of gastroenterology and hepatology 20050501

Title: Acute effects of pravastatin on cholesterol synthesis are associated with SLCO1B1 (encoding OATP1B1) haplotype *17.

Journal: Pharmacogenetics and genomics 20050501

Title: Total first-year costs of acute coronary syndrome in a managed care setting.

Journal: Journal of managed care pharmacy : JMCP 20050501

Title: Value for money in disease management of acute coronary syndrome--the price of aspirin to reduce the costs of ACS.

Journal: Journal of managed care pharmacy : JMCP 20050501

Title: The beneficial effects of lipid-lowering drugs beyond lipid-lowering effects: a comparative study with pravastatin, atorvastatin, and fenofibrate in patients with type IIa and type IIb hyperlipidemia.

Journal: Metabolism: clinical and experimental 20050501

Title: A community-based, randomized trial of ezetimibe added to statin therapy to attain NCEP ATP III goals for LDL cholesterol in hypercholesterolemic patients: the ezetimibe add-on to statin for effectiveness (EASE) trial.

Journal: Mayo Clinic proceedings 20050501

Title: National trends in statin use by coronary heart disease risk category.

Journal: PLoS medicine 20050501

Title: [Effects of pravastatin, fosinopril and their combination on myocardium TNF-alpha expression and ventricular remodeling after myocardial infarction in rats].

Journal: Zhonghua xin xue guan bing za zhi 20050501

Title: Gitelman's syndrome presenting as intolerance to statin therapy.

Journal: Annals of clinical biochemistry 20050501

Title: Pravastatin attenuates ceramide-induced cytotoxicity in mouse cerebral endothelial cells with HIF-1 activation and VEGF upregulation.

Journal: Annals of the New York Academy of Sciences 20050501

Title: Cardiac preconditioning during percutaneous coronary interventions.

Journal: Cardiovascular drugs and therapy 20050501

Title: Effectiveness of statins for secondary prevention in elderly patients after acute myocardial infarction: an evaluation of class effect.

Journal: CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20050426

Title: Quantification of pravastatin in human plasma and urine after solid phase extraction using high performance liquid chromatography with ultraviolet detection.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050425

Title: Effects of switching statins on lipid and apolipoprotein ratios in the MERCURY I study.

Journal: International journal of cardiology 20050420

Title: Statins potentiate the IFN-gamma-induced upregulation of group IIA phospholipase A2 in human aortic smooth muscle cells and HepG2 hepatoma cells.

Journal: Biochimica et biophysica acta 20050415

Title: White blood cell count predicts reduction in coronary heart disease mortality with pravastatin.

Journal: Circulation 20050412

Title: [The PROVE IT-TIMI-22 study or the biter being bit].

Journal: Revue medicale suisse 20050406

Title: Beneficial effect of simvastatin and pravastatin treatment on adverse cardiac remodelling and glomeruli loss in spontaneously hypertensive rats.

Journal: Clinical science (London, England : 1979) 20050401

Title: Differential interaction of 3-hydroxy-3-methylglutaryl-coa reductase inhibitors with ABCB1, ABCC2, and OATP1B1.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20050401

Title: Efficacy and safety of pravastatin in children and adolescents with heterozygous familial hypercholesterolemia: a prospective clinical follow-up study.

Journal: The Journal of clinical endocrinology and metabolism 20050401

Title: High doses of simvastatin upregulate dopamine D1 and D2 receptor expression in the rat prefrontal cortex: possible involvement of endothelial nitric oxide synthase.

Journal: British journal of pharmacology 20050401

Title: Measurement of saturable and non-saturable components of anandamide uptake into P19 embryonic carcinoma cells in the presence of fatty acid-free bovine serum albumin.

Journal: Chemistry and physics of lipids 20050401

Title: Disruption of lipid rafts causes apoptotic cell death in HaCaT keratinocytes.

Journal: Experimental dermatology 20050401

Title: Synthesis and structure-activity relationship of 4-substituted benzoic acids and their inhibitory effect on the biosynthesis of fatty acids and sterols.

Journal: Archiv der Pharmazie 20050401

Title: Lovastatin-induced apoptosis in human melanoma cell lines.

Journal: Melanoma research 20050401

Title: Statin-induced vascular smooth muscle cell apoptosis: a possible role in the prevention of restenosis?

Journal: Current drug targets. Cardiovascular & haematological disorders 20050401

Title: Anti-oxidative effect of fluvastatin in hyperlipidemic type 2 diabetic patients.

Journal: Endocrine journal 20050401

Title: [Effects of atorvastatin, fluvastatin, pravastatin, and simvastatin on endothelial function, lipid peroxidation, and aortic atherosclerosis in hypercholesterolemic rabbits].

Journal: Arquivos brasileiros de cardiologia 20050401

Title: Effect of anticholesterol therapy on soluble ICAM-1 in chronic stroke patients with hyperlipidemia.

Journal: The Tokai journal of experimental and clinical medicine 20050401

Title: Electrocardiographic events and cholesterol reduction with pravastatin in patients with hypercholesterolemia: the Hokuriku Lipid Coronary Heart Disease Study-Pravastatin Atherosclerosis Trial.

Journal: International journal of cardiology 20050330

Title: Plaque rupture after short periods of fat feeding in the apolipoprotein E-knockout mouse: model characterization and effects of pravastatin treatment.

Journal: Circulation 20050322

Title: Not all statins are alike: induced rhabdomyolysis on changing from one statin to another one.

Journal: International journal of cardiology 20050310

Title: [Protective effects of pravastatin against atherosclerosis in children with familial hypercholesterolemia].

Journal: Revue medicale suisse 20050302

Title: Role of organic anion transporter OATP1B1 (OATP-C) in hepatic uptake of irinotecan and its active metabolite, 7-ethyl-10-hydroxycamptothecin: in vitro evidence and effect of single nucleotide polymorphisms.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20050301

Title: Differential effect of LFA703, pravastatin, and fluvastatin on production of IL-18 and expression of ICAM-1 and CD40 in human monocytes.

Journal: Journal of leukocyte biology 20050301

Title: Paradoxical effects of statins on aortic valve myofibroblasts and osteoblasts: implications for end-stage valvular heart disease.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20050301

Title: HMG-CoA reductase inhibitors, statins, induce phosphorylation of Mdm2 and attenuate the p53 response to DNA damage.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20050301

Title: Effects of statins on vascular function of endothelin-1.

Journal: British journal of pharmacology 20050301

Title: Effects of fosinopril and pravastatin on carotid intima-media thickness in subjects with increased albuminuria.

Journal: Stroke 20050301

Title: Intensive versus moderate lipid lowering with statins in acute coronary syndromes.

Journal: Current atherosclerosis reports 20050301

Title: Reversal of atherosclerosis with aggressive lipid lowering.

Journal: Current atherosclerosis reports 20050301

Title: Isotopomer spectral analysis of intermediates of cholesterol synthesis in patients with cerebrotendinous xanthomatosis.

Journal: Metabolism: clinical and experimental 20050301

Title: Modulation of the inflammatory process by statins.

Journal: Timely topics in medicine. Cardiovascular diseases 20050301

Title: Commentary. Additive benefits of pravastatin and aspirin to decrease risks of cardiovascular disease: randomized and observational comparisons of secondary prevention trials and their meta-analyses.

Journal: Perspectives in vascular surgery and endovascular therapy 20050301

Title: A simultaneous assessment of CYP3A4 metabolism and induction in the DPX-2 cell line.

Journal: The AAPS journal 20050301

Title: How common is rhabdomyolysis in patients receiving lipid-lowering therapy?

Journal: Nature clinical practice. Cardiovascular medicine 20050301

Title: Pravastatin may prevent disease progression in normocholesterolemic people with coronary artery disease. Commentary.

Journal: Evidence-based cardiovascular medicine 20050301

Title: By the way, doctor. I take Pravachol to control my cholesterol, and because of high triglycerides, my doctor wants to add TriCor. But my pharmacist warns against taking both medications. If I don't take TriCor, are there alternatives?

Journal: Harvard health letter 20050301

Title: [Clinical protocol. Pravastatin for the prevention of the destruction of the nutritional status of hemodialysis patients exhibiting chronic inflammation].

Journal: Nephrologie & therapeutique 20050301

Title: Ongoing clinical trials of the pleiotropic effects of statins.

Journal: Vascular health and risk management 20050301

Title: Differential associations between actual and expected GP practice prescribing rates for statins, ACE inhibitors, and beta-blockers: a cross-sectional study in England.

Journal: Therapeutics and clinical risk management 20050301

Title: Update of antibiotic trials for secondary prevention of coronary heart disease.

Journal: Future cardiology 20050301

Title: Public welfare agenda or corporate research agenda?

Journal: Mens sana monographs 20050301

Title: Quantitative determination of pravastatin and R-416, its main metabolite in human plasma, by liquid chromatography-tandem mass spectrometry.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050225

Title: Relaxant effects of pravastatin, atorvastatin and cerivastatin on isolated rat aortic rings.

Journal: Life sciences 20050225

Title: Inhibitory effect of fluvastatin on ileal ulcer formation in rats induced by nonsteroidal antiinflammatory drug.

Journal: World journal of gastroenterology 20050221

Title: A prospective trial to evaluate the safety and efficacy of pravastatin for the treatment of refractory chronic graft-versus-host disease.

Journal: Transplantation 20050215

Title: Chronic administration of statins alters multiple gene expression patterns in mouse cerebral cortex.

Journal: The Journal of pharmacology and experimental therapeutics 20050201

Title: Long-term effects of statins on arterial pressure and stiffness of hypertensives.

Journal: Journal of human hypertension 20050201

Title: Statins as coronary vasodilators in isolated bovine coronary arteries--involvement of PGI2 and NO.

Journal: Prostaglandins, leukotrienes, and essential fatty acids 20050201

Title: A literature search on pharmacokinetic drug interactions of statins and analysis of how such interactions are reflected in package inserts in Japan.

Journal: Journal of clinical pharmacy and therapeutics 20050201

Title: Chemical, pharmacokinetic and pharmacodynamic properties of statins: an update.

Journal: Fundamental & clinical pharmacology 20050201

Title: Effects of rosuvastatin, atorvastatin, simvastatin, and pravastatin on atherogenic dyslipidemia in patients with characteristics of the metabolic syndrome.

Journal: The American journal of cardiology 20050201

Title: The influence of guidelines on the use of statins: analysis of prescribing trends 1998-2002.

Journal: British journal of clinical pharmacology 20050201

Title: Oral pre-treatment with rosuvastatin protects porcine myocardium from ischaemia/reperfusion injury via a mechanism related to nitric oxide but not to serum cholesterol level.

Journal: Acta physiologica Scandinavica 20050201

Title: Pravastatin modulates early diabetic nephropathy in an experimental model of diabetic renal disease.

Journal: The Journal of surgical research 20050201

Title: Rosuvastatin is cost-effective in treating patients to low-density lipoprotein-cholesterol goals compared with atorvastatin, pravastatin and simvastatin: analysis of the STELLAR trial.

Journal: European journal of cardiovascular prevention and rehabilitation : official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology 20050201

Title: The relation between hypoalbuminemia and compliance and intima-media thickness of carotid artery in continuous ambulatory peritoneal dialysis patients.

Journal: Journal of Korean medical science 20050201

Title: Cost-efficacy analysis of 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitors based on results of the STELLAR trial: clinical implications for therapeutic selection.

Journal: Pharmacotherapy 20050201

Title: Characterization of secretory intestinal transport of phenolsulfonphthalein.

Journal: Drug metabolism and pharmacokinetics 20050201

Title: Effects of switching pravastatin to cerivastatin on C-reactive protein, butyrylcholinesterase, and lipids.

Journal: Current medical research and opinion 20050201

Title: [Effects of interaction between vascular endothelial cells and monocytes on expression of matrix metalloproteinase-2 and of tissue inhibitor of metalloproteinases 2 and regulation of pravastatin].

Journal: Zhonghua bing li xue za zhi = Chinese journal of pathology 20050201

Title: Effect of statins on LDL particle size in patients with familial combined hyperlipidemia: a comparison between atorvastatin and pravastatin.

Journal: Nutrition, metabolism, and cardiovascular diseases : NMCD 20050201

Title: Cholesteryl ester transfer protein TaqIB variant, high-density lipoprotein cholesterol levels, cardiovascular risk, and efficacy of pravastatin treatment: individual patient meta-analysis of 13,677 subjects.

Journal: Circulation 20050125

Title: C-reactive protein levels and outcomes after statin therapy.

Journal: The New England journal of medicine 20050106

Title: Statin therapy, LDL cholesterol, C-reactive protein, and coronary artery disease.

Journal: The New England journal of medicine 20050106

Title: Effects of combined estriol/pravastatin therapy on intima-media thickness of common carotid artery in hyperlipidemic postmenopausal women.

Journal: Gynecologic and obstetric investigation 20050101

Title: Inhibitory effects of mevastatin and a geranylgeranyl transferase I inhibitor (GGTI-2166) on mononuclear osteoclast formation induced by receptor activator of NF kappa B ligand (RANKL) or tumor necrosis factor-alpha (TNF-alpha).

Journal: Biochemical pharmacology 20050101

Title: Pravastatin therapy is associated with reduction in coronary allograft vasculopathy in pediatric heart transplantation.

Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20050101

Title: Effect of pravastatin on impaired endothelium-dependent relaxation induced by lysophosphatidylcholine in rat aorta.

Journal: Acta pharmacologica Sinica 20050101

Title: Are Canadian guidelines for cholesterol lowering in high-risk patients optimal?

Journal: The Canadian journal of cardiology 20050101

Title: Changes in lipids over twelve months after initiating protease inhibitor therapy among persons treated for HIV/AIDS.

Journal: Lipids in health and disease 20050101

Title: Review of efficacy of rosuvastatin 5 mg.

Journal: International journal of clinical practice 20050101

Title: PROVE IT then believe it.

Journal: International journal of clinical practice 20050101

Title: Preventing type 2 diabetes mellitus.

Journal: The Journal of the American Board of Family Practice 20050101

Title: A comparative crossover study of the effects of fluvastatin and pravastatin (FP-COS) on circulating autoantibodies to oxidized LDL in patients with hypercholesterolemia.

Journal: Journal of atherosclerosis and thrombosis 20050101

Title: Risk evaluation of coronary heart disease and cerebrovascular disease by the Japan Atherosclerosis Society Guidelines 2002 using the cohort of the Holicos-PAT study.

Journal: Journal of atherosclerosis and thrombosis 20050101

Title: Prevalence of potentially severe drug-drug interactions in ambulatory patients with dyslipidaemia receiving HMG-CoA reductase inhibitor therapy.

Journal: Drug safety 20050101

Title: Do the pleiotropic effects of statins in the vasculature predict a role in inflammatory diseases?

Journal: Arthritis research & therapy 20050101

Title: The effects of cholesterol lowering with simvastatin on cause-specific mortality and on cancer incidence in 20,536 high-risk people: a randomised placebo-controlled trial [ISRCTN48489393].

Journal: BMC medicine 20050101

Title: Myoglobin clearance by super high-flux hemofiltration in a case of severe rhabdomyolysis: a case report.

Journal: Critical care (London, England) 20050101

Title: Mevastatin induces apoptosis in HL60 cells dependently on decrease in phosphorylated ERK.

Journal: Molecular and cellular biochemistry 20050101

Title: The 'Statinth' wonder of the world: a panacea for all illnesses or a bubble about to burst.

Journal: Journal of negative results in biomedicine 20050101

Title: A pharmacoeconomic evaluation of statins in the treatment of hypercholesterolaemia in the primary care setting in Spain.

Journal: PharmacoEconomics 20050101

Title: Adverse events with concomitant amiodarone and statin therapy.

Journal: Preventive cardiology 20050101

Title: Ezetimibe: a review of its metabolism, pharmacokinetics and drug interactions.

Journal: Clinical pharmacokinetics 20050101

Title: Effect of rosuvastatin on outcomes in chronic haemodialysis patients - design and rationale of the AURORA study.

Journal: Current controlled trials in cardiovascular medicine 20050101

Title: Acute myopathy in a patient with concomitant use of pravastatin and colchicine.

Journal: The Annals of pharmacotherapy 20050101

Title: Herb-drug interactions: a literature review.

Journal: Drugs 20050101

Title: [Clinical study of pravastatin with different dosage in early admission period in patients with unstable angina].

Journal: Zhonghua xin xue guan bing za zhi 20050101

Title: Chlamydophila pneumoniae induces expression of toll-like receptor 4 and release of TNF-alpha and MIP-2 via an NF-kappaB pathway in rat type II pneumocytes.

Journal: Respiratory research 20050101

Title: Comparison of rosuvastatin and atorvastatin for lipid lowering in patients with type 2 diabetes mellitus: results from the URANUS study.

Journal: Cardiovascular diabetology 20050101

Title: Statins research unfinished saga: desirability versus feasibility.

Journal: Cardiovascular diabetology 20050101

Title: A cluster randomized trial to assess the impact of opinion leader endorsed evidence summaries on improving quality of prescribing for patients with chronic cardiovascular disease: rationale and design [ISRCTN26365328].

Journal: BMC cardiovascular disorders 20050101

Title: Association of CETP TaqI and APOE polymorphisms with type II diabetes mellitus in North Indians: a case control study.

Journal: BMC endocrine disorders 20050101

Title: Stimulatory effects of statins on bone marrow-derived mesenchymal stem cells. Study of a new therapeutic agent for fracture.

Journal: Bio-medical materials and engineering 20050101

Title: Medication adherence trends with statins.

Journal: Advances in therapy 20050101

Title: HMG-CoA reductase inhibitors suppress the development and progression of carotid artery intimal-medial thickening in hypercholesterolemic type 2 diabetic patients.

Journal: Journal of atherosclerosis and thrombosis 20050101

Title: Pitavastatin enhanced lipoprotein lipase expression in 3T3-L1 preadipocytes.

Journal: Journal of atherosclerosis and thrombosis 20050101

Title: The effect of prior statin use on 30-day mortality for patients hospitalized with community-acquired pneumonia.

Journal: Respiratory research 20050101

Title: Changes in serum levels of E-selectin correlate to improved glycaemic control and reduced obesity in subjects with the metabolic syndrome.

Journal: Scandinavian journal of clinical and laboratory investigation 20050101

Title: The non-invasive documentation of coronary microcirculation impairment: role of transthoracic echocardiography.

Journal: Cardiovascular ultrasound 20050101

Title: An association study of 43 SNPs in 16 candidate genes with atorvastatin response.

Journal: The pharmacogenomics journal 20050101

Title: Expression and subcellular localization of aquaporin water channels in the polarized hepatocyte cell line, WIF-B.

Journal: BMC physiology 20050101

Title: Fenofibrate Intervention and Event Lowering in Diabetes (FIELD) study: baseline characteristics and short-term effects of fenofibrate [ISRCTN64783481].

Journal: Cardiovascular diabetology 20050101

Title: [Isoprenoid pigments in representatives of the family Microbacteriaceae].

Journal: Mikrobiologiia 20050101

Title: [Severe muscle disorders associated with statins: analysis of cases notified in France up to the end of February 2002 and data concerning the risk profile of cerivastatin].

Journal: Therapie 20050101

Title: Statins and LDL-cholesterol lowering: an overview.

Journal: Current medical research and opinion 20050101

Title: JTT-130, a microsomal triglyceride transfer protein (MTP) inhibitor lowers plasma triglycerides and LDL cholesterol concentrations without increasing hepatic triglycerides in guinea pigs.

Journal: BMC cardiovascular disorders 20050101

Title: The clopidogrel after surgery for coronary artery disease (CASCADE) randomized controlled trial: clopidogrel and aspirin versus aspirin alone after coronary bypass surgery [NCT00228423].

Journal: Current controlled trials in cardiovascular medicine 20050101

Title: Considerations in the treatment of dyslipidemia associated with chronic kidney failure and renal transplantation.

Journal: Preventive cardiology 20050101

Title: Treatment of dyslipidemia with lovastatin and ezetimibe in an adolescent with cholesterol ester storage disease.

Journal: Lipids in health and disease 20050101

Title: Unblinding of trial participants to their treatment allocation: lessons from the Prospective Study of Pravastatin in the Elderly at Risk (PROSPER).

Journal: Clinical trials (London, England) 20050101

Title: Cost-effectiveness of rosuvastatin compared with other statins from a managed care perspective.

Journal: Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research 20050101

Title: Inhibitory effect of pravastatin on transforming growth factor beta1-inducible gene h3 expression in a rat model of chronic cyclosporine nephropathy.

Journal: American journal of nephrology 20050101

Title: Lipids and stroke: the opportunity of lipid-lowering treatment.

Journal: Cerebrovascular diseases (Basel, Switzerland) 20050101

Title: Quality of life after acute myocardial infarction: a comparison of diabetic versus non-diabetic acute myocardial infarction patients in Quebec acute care hospitals.

Journal: Health and quality of life outcomes 20050101

Title: [Effect of n-3 polyunsaturated fatty acids on plasma lipid, LDL lipoperoxidation, homocysteine and inflammation indicators in diabetic dyslipidemia treated with statin + fibrate combination].

Journal: Casopis lekaru ceskych 20050101

Title: Isolation of a cDNA encoding the alpha-subunit of CAAX-prenyltransferases from Catharanthus roseus and the expression of the active recombinant protein farnesyltransferase.

Journal: Cellular & molecular biology letters 20050101

Title: [Hypertension combined with atherosclerotic lesions in carotid arteries: should angiotensin converting enzyme inhibitors be prescribed?].

Journal: Kardiologiia 20050101

Title: Pravastatin improves insulin resistance in dyslipidemic patients.

Journal: Journal of atherosclerosis and thrombosis 20050101

Title: The status of lipid management in 1,836 patients with coronary artery disease: a multicenter survey to evaluate the percentage of Japanese coronary artery disease patients achieving the target low-density lipoprotein cholesterol level specified by the Japan Atherosclerosis Society.

Journal: Journal of atherosclerosis and thrombosis 20050101

Title: Comparison of the effects of D-003, a mixture of high-molecular-weight aliphatic acids from sugarcane wax, and pravastatin on bones and osteoclast apoptosis of ovariectomized rats.

Journal: Drugs under experimental and clinical research 20050101

Title: HMG-CoA reductase inhibitors reduce matrix metalloproteinase-9 activity in human varicose veins.

Journal: European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes 20050101

Title: [Evaluation of thrombin generation and clot bound thrombin in plasma of hyperlipidemic patients treated with statins].

Journal: Przeglad lekarski 20050101

Title: [Statins in patients with renal failure--the current therapeutic status].

Journal: Przeglad lekarski 20050101

Title: The University of California at Los Angeles heart transplantation experience.

Journal: Clinical transplants 20050101

Title: Successful Treatment with Colesevelam HCl and Pravastatin in a Patient Previously Hospitalised with Severe Normal CPK Myopathy on Introduction of Simvastatin.

Journal: Clinical drug investigation 20050101

Title: Aliskiren in hypertension: evidence for its potential therapeutic value.

Journal: Core evidence 20050101

Title: Chronic cyclosporine nephrotoxicity: new insights and preventive strategies.

Journal: Yonsei medical journal 20041231

Title: Mechanistic and epidemiologic considerations in the evaluation of adverse birth outcomes following gestational exposure to statins.

Journal: American journal of medical genetics. Part A 20041215

Title: Statin-associated exacerbation of myasthenia gravis.

Journal: Neurology 20041214

Title: HMG-CoA reductase inhibitors induce COX-2 gene expression in murine macrophages: role of MAPK cascades and promoter elements for CREB and C/EBPbeta.

Journal: Experimental cell research 20041210

Title: Involvement of multiple transporters in the efflux of 3-hydroxy-3-methylglutaryl-CoA reductase inhibitors across the blood-brain barrier.

Journal: The Journal of pharmacology and experimental therapeutics 20041201

Title: [Statin therapy in patients with acute coronary syndrome. 'Prove-it' study].

Journal: Der Internist 20041201

Title: Different effects of antihypertensive regimens based on fosinopril or hydrochlorothiazide with or without lipid lowering by pravastatin on progression of asymptomatic carotid atherosclerosis: principal results of PHYLLIS--a randomized double-blind trial.

Journal: Stroke 20041201

Title: Statins inhibit synthesis of an oxysterol ligand for the liver x receptor in human macrophages with consequences for cholesterol flux.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20041201

Title: Pharmacogenetic study of statin therapy in cholesterol reduction.

Journal: Current hypertension reports 20041201

Title: Intensive statin therapy in acute coronary syndromes: clinical benefits and vascular biology.

Journal: Current opinion in lipidology 20041201

Title: Therapy and clinical trials: clinical therapy and trials.

Journal: Current opinion in lipidology 20041201

Title: Incidence of hospitalized rhabdomyolysis in patients treated with lipid-lowering drugs.

Journal: JAMA 20041201

Title: Hypolipidemic drugs can change the composition of rat brain lipids.

Journal: The Tohoku journal of experimental medicine 20041201

Title: Effects of a statin group drug, pravastatin, on the insulin resistance in patients with metabolic syndrome.

Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20041201

Title: Effect of aggressive versus moderate lipid-lowering therapy on myocardial ischemia: the rationale, design, and baseline characteristics of the Study Assessing Goals in the Elderly (SAGE).

Journal: American heart journal 20041201

Title: Consistency in efficacy and safety of ezetimibe coadministered with statins for treatment of hypercholesterolemia in women and men.

Journal: Journal of women's health (2002) 20041201

Title: A novel variant allele of OATP-C (SLCO1B1) found in a Japanese patient with pravastatin-induced myopathy.

Journal: Drug metabolism and pharmacokinetics 20041201

Title: What did PROVE-IT prove?

Journal: Diabetes technology & therapeutics 20041201

Title: Multiple antiplatelet effects of clopidogrel are not modulated by statin type in patients undergoing percutaneous coronary intervention.

Journal: Platelets 20041201

Title: Trial finds administering pravastatin early after symptom onset does not improve outcomes in people with acute coronary syndromes.

Journal: Evidence-based cardiovascular medicine 20041201

Title: Fluvastatin and lovastatin but not pravastatin induce neuroglial differentiation in human mesenchymal stem cells.

Journal: Journal of cellular biochemistry 20041115

Title: Inhibition of geranylgeranylation mediates the effects of 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase inhibitors on microglia.

Journal: The Journal of biological chemistry 20041112

Title: Statins enhance migratory capacity by upregulation of the telomere repeat-binding factor TRF2 in endothelial progenitor cells.

Journal: Circulation 20041109

Title: Effects of fosinopril and pravastatin on cardiovascular events in subjects with microalbuminuria.

Journal: Circulation 20041102

Title: Differential multidrug resistance-associated protein 1 through 6 isoform expression and function in human intestinal epithelial Caco-2 cells.

Journal: The Journal of pharmacology and experimental therapeutics 20041101

Title: Disorder resembling Guillain-Barré syndrome on initiation of statin therapy.

Journal: Muscle & nerve 20041101

Title: Statin therapy in kidney disease populations: potential benefits beyond lipid lowering and the need for clinical trials.

Journal: Current opinion in nephrology and hypertension 20041101

Title: Framingham score and microalbuminuria: combined future targets for primary prevention?

Journal: Kidney international. Supplement 20041101

Title: Elevated soluble tumor necrosis factor receptor levels in non-obese adults with the atherogenic dyslipoproteinemia.

Journal: Atherosclerosis 20041101

Title: Comparative pharmacokinetic interaction profiles of pravastatin, simvastatin, and atorvastatin when coadministered with cytochrome P450 inhibitors.

Journal: The American journal of cardiology 20041101

Title: Functional analysis of single nucleotide polymorphisms of hepatic organic anion transporter OATP1B1 (OATP-C).

Journal: Pharmacogenetics 20041101

Title: Statins: can the new generation make an impression?

Journal: Expert opinion on emerging drugs 20041101

Title: Tracking regression and progression of atherosclerosis in human carotid arteries using high-resolution magnetic resonance imaging.

Journal: Magnetic resonance imaging 20041101

Title: Effects of statins on circulating oxidized low-density lipoprotein in patients with hypercholesterolemia.

Journal: Japanese heart journal 20041101

Title: Can pravastatin lower coronary event rate if HDL and LDL cholesterol are at low levels?

Journal: Nature clinical practice. Cardiovascular medicine 20041101

Title: Optimal windows of statin use for immediate infarct limitation: 5'-nucleotidase as another downstream molecule of phosphatidylinositol 3-kinase.

Journal: Circulation 20041012

Title: Gemfibrozil and its glucuronide inhibit the organic anion transporting polypeptide 2 (OATP2/OATP1B1:SLC21A6)-mediated hepatic uptake and CYP2C8-mediated metabolism of cerivastatin: analysis of the mechanism of the clinically relevant drug-drug interaction between cerivastatin and gemfibrozil.

Journal: The Journal of pharmacology and experimental therapeutics 20041001

Title: Effects of pravastatin on the expression of ATP-binding cassette transporter A1.

Journal: The Journal of pharmacology and experimental therapeutics 20041001

Title: Randomized, controlled trial of secondary prevention of coronary sclerosis in normocholesterolemic patients using pravastatin: final 5-year angiographic follow-up of the Prevention of Coronary Sclerosis (PCS) study.

Journal: International journal of cardiology 20041001

Title: An approach to the residence time distribution for stochastic multi-compartment models.

Journal: Mathematical biosciences 20041001

Title: Effect of pravastatin on left ventricular mass by activation of myocardial K ATP channels in hypercholesterolemic rabbits.

Journal: Atherosclerosis 20041001

Title: Safety of rosuvastatin.

Journal: The American journal of cardiology 20041001

Title: [Endothelial dysfunction, inflammation and statins: new evidences].

Journal: Revista espanola de cardiologia 20041001

Title: [Effect of the early administration of pravastatin on C-reactive protein and interleukin-6 levels in the acute phase of myocardial infarction with ST segment elevation].

Journal: Revista espanola de cardiologia 20041001

Title: Mevastatin inhibits ovarian theca-interstitial cell proliferation and steroidogenesis.

Journal: Fertility and sterility 20041001

Title: Genistein supplementation inhibits atherosclerosis with stabilization of the lesions in hypercholesterolemic rabbits.

Journal: Journal of Korean medical science 20041001

Title: Ezetimibe: new preparation. A cholesterol-lowering drug with no clinical advantage.

Journal: Prescrire international 20041001

Title: Nevirapine and efavirenz elicit different changes in lipid profiles in antiretroviral-therapy-naive patients infected with HIV-1.

Journal: PLoS medicine 20041001

Title: Therapeutic effects of ml-236B in primary hypercholesterolemia. 1980.

Journal: Atherosclerosis. Supplements 20041001

Title: Effects of an inhibitor of 3-hydroxy-3-methylglutaryl coenzyme a reductase on serum lipoproteins and ubiquinone-10 levels in patients with familial hypercholesterolemia. 1981.

Journal: Atherosclerosis. Supplements 20041001

Title: Lowering plasma cholesterol by raising ldl receptors. 1981.

Journal: Atherosclerosis. Supplements 20041001

Title: Mevinolin and colestipol stimulate receptor-mediated clearance of low density lipoprotein from plasma in familial hypercholeserolemia heterozygotes. 1983.

Journal: Atherosclerosis. Supplements 20041001

Title: Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia. 1995.

Journal: Atherosclerosis. Supplements 20041001

Title: Guidelines for lowering lipids to reduce coronary artery disease risk: a comparison of rosuvastatin with atorvastatin, pravastatin, and simvastatin for achieving lipid-lowering goals. 2003.

Journal: Atherosclerosis. Supplements 20041001

Title: Effects of lovastatin and pravastatin on amyloid processing and inflammatory response in TgCRND8 brain.

Journal: Neurochemical research 20041001

Title: Eisai hyperbilirubinemic rat (EHBR) as an animal model affording high drug-exposure in toxicity studies on organic anions.

Journal: Drug metabolism and pharmacokinetics 20041001

Title: Biliary excretion of bile acids and organic anions in rats with dichloroethylene-induced bile canalicular injury.

Journal: Journal of gastroenterology 20041001

Title: How low should your cholesterol go? Even lower may be better. For those at highest risk, very low cholesterol levels may help prevent a second heart attack or stroke.

Journal: Health news (Waltham, Mass.) 20041001

Title: Effect of pravastatin on cardiovascular events in people with chronic kidney disease.

Journal: Circulation 20040921

Title: Cholesterol synthesis and import contribute to protective cholesterol increments in acute myeloid leukemia cells.

Journal: Blood 20040915

Title: Identification and chemical profiling of monacolins in red yeast rice using high-performance liquid chromatography with photodiode array detector and mass spectrometry.

Journal: Journal of pharmaceutical and biomedical analysis 20040903

Title: [Lowering of cholesterol. What role is played by the choice of statins?].

Journal: MMW Fortschritte der Medizin 20040902

Title: An integrated evaluation of endothelial constitutive nitric oxide synthase polymorphisms and coronary artery disease in men.

Journal: Clinical science (London, England : 1979) 20040901

Title: Effects of Dai-saiko-to (Da-Chai-Hu-Tang) on plasma lipids and atherosclerotic lesions in female heterozygous heritable Kurosawa and Kusanagi-hypercholesterolemic (KHC) rabbits.

Journal: Pharmacological research 20040901

Title: Early effect of pravastatin on serum soluble CD40L, matrix metalloproteinase-9, and C-reactive protein in patients with acute myocardial infarction.

Journal: Clinical chemistry 20040901

Title: Low-density lipoprotein reduction in high-risk patients: how low do you go?

Journal: Current atherosclerosis reports 20040901

Title: Lessons learned from the prospective pravastatin pooling project.

Journal: Current atherosclerosis reports 20040901

Title: ALLHAT-LLT: questions, questions, and more questions (and some answers).

Journal: Current atherosclerosis reports 20040901

Title: HMG-CoA reductase inhibitors and the risk of vertebral fracture.

Journal: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20040901

Title: Prediction of in vivo biliary clearance from the in vitro transcellular transport of organic anions across a double-transfected Madin-Darby canine kidney II monolayer expressing both rat organic anion transporting polypeptide 4 and multidrug resistance associated protein 2.

Journal: Molecular pharmacology 20040901

Title: Statins and newly diagnosed diabetes.

Journal: British journal of clinical pharmacology 20040901

Title: Is decreased libido associated with the use of HMG-CoA-reductase inhibitors?

Journal: British journal of clinical pharmacology 20040901

Title: Design and baseline characteristics of a study of primary prevention of coronary events with pravastatin among Japanese with mildly elevated cholesterol levels.

Journal: Circulation journal : official journal of the Japanese Circulation Society 20040901

Title: Atorvastatin versus pravastatin: intensive versus moderate lipid lowering.

Journal: Expert opinion on pharmacotherapy 20040901

Title: Inhibitors of HMG-CoA reductase reduce receptor-mediated endocytosis in human kidney proximal tubular cells.

Journal: Journal of the American Society of Nephrology : JASN 20040901

Title: Statins inhibit reoxygenation-induced cardiomyocyte apoptosis: role for glycogen synthase kinase 3beta and transcription factor beta-catenin.

Journal: Journal of molecular and cellular cardiology 20040901

Title: Oral administration of pravastatin reduces egg cholesterol but not plasma cholesterol in laying hens.

Journal: Poultry science 20040901

Title: New decalin derivatives, eujavanoic acids A and B, from Eupenicillium javanicum.

Journal: Journal of natural products 20040901

Title: Rosuvastatin in the management of hyperlipidemia.

Journal: Clinical therapeutics 20040901

Title: Effects of rosuvastatin versus atorvastatin, simvastatin, and pravastatin on non-high-density lipoprotein cholesterol, apolipoproteins, and lipid ratios in patients with hypercholesterolemia: additional results from the STELLAR trial.

Journal: Clinical therapeutics 20040901

Title: Antiinflammatory effects of angiotensin II subtype 1 receptor blockade in hypertensive patients with microinflammation.

Journal: Circulation 20040831

Title: Pitavastatin increases ABCA1-mediated lipid efflux from Fu5AH rat hepatoma cells.

Journal: Biochemical and biophysical research communications 20040827

Title: Glucose-potentiated chemotaxis in human vascular smooth muscle is dependent on cross-talk between the PI3K and MAPK signaling pathways.

Journal: Circulation research 20040820

Title: Effects of pravastatin on progression of glucose intolerance and cardiovascular remodeling in a type II diabetes model.

Journal: Journal of the American College of Cardiology 20040818

Title: Antioxidant effects of statins via S-nitrosylation and activation of thioredoxin in endothelial cells: a novel vasculoprotective function of statins.

Journal: Circulation 20040817

Title: HMG-CoA reductase inhibitors for lowering elevated levels of C-reactive protein.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20040815

Title: Intensive versus moderate lipid lowering with statins after acute coronary syndromes.

Journal: The New England journal of medicine 20040812

Title: Intensive versus moderate lipid lowering with statins after acute coronary syndromes.

Journal: The New England journal of medicine 20040812

Title: Intensive versus moderate lipid lowering with statins after acute coronary syndromes.

Journal: The New England journal of medicine 20040812

Title: Intensive versus moderate lipid lowering with statins after acute coronary syndromes.

Journal: The New England journal of medicine 20040812

Title: Intensive versus moderate lipid lowering with statins after acute coronary syndromes.

Journal: The New England journal of medicine 20040812

Title: Updated guidelines support even lower cholesterol levels for at-risk patients.

Journal: Report on medical guidelines & outcomes research 20040806

Title: [Patient feels completely well. The PROCAM Score first reveals the high infarct risk].

Journal: MMW Fortschritte der Medizin 20040805

Title: Tamoxifen treatment reverses the adverse effects of chemotherapy-induced ovarian failure on serum lipids.

Journal: British journal of cancer 20040802

Title: Treatment of type IIb familial combined hyperlipidemia with the combination pravastatin-piperazine sultosilate.

Journal: European journal of pharmacology 20040802

Title: Acute activation and phosphorylation of endothelial nitric oxide synthase by HMG-CoA reductase inhibitors.

Journal: American journal of physiology. Heart and circulatory physiology 20040801

Title: Chronic mevastatin modulates receptor-dependent vascular contraction in eNOS-deficient mice.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20040801

Title: Statins upregulate PCSK9, the gene encoding the proprotein convertase neural apoptosis-regulated convertase-1 implicated in familial hypercholesterolemia.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20040801

Title: Cholesterol-lowering independent regression and stabilization of atherosclerotic lesions by pravastatin and by antimonocyte chemoattractant protein-1 therapy in nonhuman primates.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20040801

Title: Interleukin-6, fibrin D-dimer, and coagulation factors VII and XIIa in prediction of coronary heart disease.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20040801

Title: Effects of pravastatin and bezafibrate on biliary lipid excretion and hepatic expression of Abcg5 and Abcg8 in the rat.

Journal: Journal of gastroenterology and hepatology 20040801

Title: CETP gene variation: relation to lipid parameters and cardiovascular risk.

Journal: Current opinion in lipidology 20040801

Title: Statin therapy in the elderly.

Journal: Current opinion in lipidology 20040801

Title: AT-1 receptor blockade prevents proteinuria, renal failure, hyperlipidemia, and glomerulosclerosis in the Imai rat.

Journal: Kidney international 20040801

Title: Different effects of pravastatin and cerivastatin on the media of the carotid arteries as assessed by integrated backscatter ultrasound.

Journal: Circulation journal : official journal of the Japanese Circulation Society 20040801

Title: Lipid-lowering response to statins is affected by CYP3A5 polymorphism.

Journal: Pharmacogenetics 20040801

Title: Lipid lowering therapy with fluvastatin and pravastatin in patients with HIV infection and antiretroviral therapy: comparison of efficacy and interaction with indinavir.

Journal: Infection 20040801

Title: Treatment of hyperlipidemia in cardiac transplant recipients.

Journal: American heart journal 20040801

Title: Efficacy and safety of ezetimibe coadministered with statins: randomised, placebo-controlled, blinded experience in 2382 patients with primary hypercholesterolemia.

Journal: International journal of clinical practice 20040801

Title: Lessons from the PROVE-IT trial. Higher dose of potent statin better for high-risk patients.

Journal: Cleveland Clinic journal of medicine 20040801

Title: Rosuvastatin: new preparation. Opt for statins with evidence of efficacy on clinical outcome.

Journal: Prescrire international 20040801

Title: Lipid rafts mediate the synaptic localization of alpha-synuclein.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20040728

Title: Efficacy and safety of statin therapy in children with familial hypercholesterolemia: a randomized controlled trial.

Journal: JAMA 20040721

Title: Depletion of membrane cholesterol causes ligand-independent activation of Fas and apoptosis.

Journal: Biochemical and biophysical research communications 20040716

Title: [Decreasing LDL level moderately or drastically. Is differential therapy with statins available? (interview by Dirk Einecke)].

Journal: MMW Fortschritte der Medizin 20040708

Title: Effect of pravastatin on low-density lipoprotein oxidation and myocardial perfusion in young adults with type 1 diabetes.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20040701

Title: Understanding why older people participate in clinical trials: the experience of the Scottish PROSPER participants.

Journal: Age and ageing 20040701

Title: Moderate versus aggressive lipid lowering with statins following an acute coronary syndrome: the pravastatin or atorvastatin evaluation and infection therapy trial.

Journal: Current cardiology reports 20040701

Title: 3-Hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor (pravastatin) inhibits endothelial cell proliferation dependent on G1 cell cycle arrest.

Journal: Anti-cancer drugs 20040701

Title: Effect of pravastatin compared with placebo initiated within 24 hours of onset of acute myocardial infarction or unstable angina: the Pravastatin in Acute Coronary Treatment (PACT) trial.

Journal: American heart journal 20040701

Title: Comparison of levels of matrix metalloproteinases, tissue inhibitor of metalloproteinases, interleukins, and tissue necrosis factor in carotid endarterectomy specimens from patients on versus not on statins preoperatively.

Journal: The American journal of cardiology 20040701

Title: High plasma pravastatin concentrations are associated with single nucleotide polymorphisms and haplotypes of organic anion transporting polypeptide-C (OATP-C, SLCO1B1).

Journal: Pharmacogenetics 20040701

Title: New LDL goals: even lower?

Journal: The Johns Hopkins medical letter health after 50 20040701

Title: [Pharmacoeconomic analysis of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor therapy for the secondary prevention of coronary heart disease].

Journal: Nihon eiseigaku zasshi. Japanese journal of hygiene 20040701

Title: Pharmacogenetic study of statin therapy and cholesterol reduction.

Journal: JAMA 20040616

Title: Apoptotic injury in cultured human hepatocytes induced by HMG-CoA reductase inhibitors.

Journal: Biochemical pharmacology 20040615

Title: Mouse reduced in osteosclerosis transporter functions as an organic anion transporter 3 and is localized at abluminal membrane of blood-brain barrier.

Journal: The Journal of pharmacology and experimental therapeutics 20040601

Title: Compactin-a review.

Journal: Applied microbiology and biotechnology 20040601

Title: Rhabdomyolysis in association with simvastatin and amiodarone.

Journal: The Annals of pharmacotherapy 20040601

Title: Novel cardioprotective effects of pravastatin in human ventricular cardiomyocytes subjected to hypoxia and reoxygenation: beneficial effects of statins independent of endothelial cells.

Journal: The Journal of surgical research 20040601

Title: Effect of pravastatin on myocardial perfusion after percutaneous transluminal coronary angioplasty.

Journal: The American journal of cardiology 20040601

Title: Therapy for unresectable hepatocellular carcinoma: review of the randomized clinical trials-II: systemic and local non-embolization-based therapies in unresectable and advanced hepatocellular carcinoma.

Journal: Anti-cancer drugs 20040601

Title: Intensive lipid-lowering therapy in coronary artery disease: implications of the REVERSAL and PROVE-IT trials.

Journal: Expert opinion on investigational drugs 20040601

Title: Pravastatin has an additional depressor effect in patients undergoing long-term treatment with antihypertensive drugs.

Journal: American journal of hypertension 20040601

Title: Statins: novel additions to the dermatologic arsenal?

Journal: Experimental dermatology 20040601

Title: High doses of simvastatin, pravastatin, and cholesterol reduce brain cholesterol synthesis in guinea pigs.

Journal: Steroids 20040601

Title: [In vitro effects of mevastatin on the proliferation and apoptosis in human multiple myeloma cell line U266].

Journal: Zhongguo shi yan xue ye xue za zhi 20040601

Title: The importance of aggressive lipid management in patients at risk: evidence from recent clinical trials.

Journal: Clinical cardiology 20040601

Title: Metaanalysis of statins and survival in de novo cardiac transplantation.

Journal: Transplantation proceedings 20040601

Title: Pharmacokinetic interactions of drugs with St John's wort.

Journal: Journal of psychopharmacology (Oxford, England) 20040601

Title: Molecular basis of ML-236B production in the high-producing mutant No. 41520 of Penicillium citrinum.

Journal: The Journal of general and applied microbiology 20040601

Title: Clopidogrel-atorvastatin interaction.

Journal: Circulation 20040525

Title: Pravastatin, a 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor, reduces delayed neuronal death following transient forebrain ischemia in the adult rat hippocampus.

Journal: Neuroscience letters 20040520

Title: The microsomal triglyceride transfer protein gene-493T variant lowers cholesterol but increases the risk of coronary heart disease.

Journal: Circulation 20040518

Title: Meta-analysis of large randomized controlled trials to evaluate the impact of statins on cardiovascular outcomes.

Journal: British journal of clinical pharmacology 20040501

Title: HMG CoA reductase inhibitors and the risk of venous thrombosis among postmenopausal women.

Journal: Journal of thrombosis and haemostasis : JTH 20040501

Title: Induction of CYP3A by 2,3-oxidosqualene:lanosterol cyclase inhibitors is mediated by an endogenous squalene metabolite in primary cultured rat hepatocytes.

Journal: Molecular pharmacology 20040501

Title: Evidence for inverse effects of OATP-C (SLC21A6) 5 and 1b haplotypes on pravastatin kinetics.

Journal: Clinical pharmacology and therapeutics 20040501

Title: The effect of gemfibrozil on the pharmacokinetics of rosuvastatin.

Journal: Clinical pharmacology and therapeutics 20040501

Title: Pharmacogenetics of the CD14 endotoxin receptor polymorphism and progression of coronary atherosclerosis.

Journal: Thrombosis and haemostasis 20040501

Title: Treating low HDL-cholesterol in normocholesterolaemic patients with coronary disease: statins, fibrates or horses for courses?

Journal: European heart journal 20040501

Title: Effects of pravastatin on coronary events in 2073 patients with low levels of both low-density lipoprotein cholesterol and high-density lipoprotein cholesterol: results from the LIPID study.

Journal: European heart journal 20040501

Title: Effects of a novel antihyperlipidemic agent, S-2E, on the blood lipid abnormalities in homozygous WHHL rabbits.

Journal: Metabolism: clinical and experimental 20040501

Title: Lipitor bests Pravachol at certain doses.

Journal: Health news (Waltham, Mass.) 20040501

Title: Pravastatin in patients with nonalcoholic steatohepatitis: results of a pilot study.

Journal: Atherosclerosis 20040501

Title: Cholesterol: low is good. Lower is better. PROVE IT has doctors rethinking how to treat high cholesterol and what's a good target.

Journal: Harvard heart letter : from Harvard Medical School 20040501

Title: Cholesterol limbo: How low should the bar go. Ratcheting down LDL to extra-low levels with high-dose statins seems to work wonders.

Journal: Harvard health letter 20040501

Title: Statins and liver toxicity: a meta-analysis.

Journal: Pharmacotherapy 20040501

Title: Bioequivalence of pravastatin tablet formulations assessed in Korean males.

Journal: International journal of clinical pharmacology and therapeutics 20040501

Title: [The Prosper-Study: practical consequences?].

Journal: Der Internist 20040501

Title: 'Major surprise' in a new study means likely changes in treatment.

Journal: Heart advisor 20040501

Title: [Comparison of effects of taizhi' an capsule and pravastatin on vascular endothelial function in senile patients with coronary heart disease].

Journal: Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20040501

Title: Intensive versus moderate lipid lowering with statins after acute coronary syndromes.

Journal: The New England journal of medicine 20040408

Title: Intensive statin therapy--a sea change in cardiovascular prevention.

Journal: The New England journal of medicine 20040408

Title: HMG-CoA reductase inhibitor attenuates platelet adhesion in intestinal venules of hypercholesterolemic mice.

Journal: American journal of physiology. Heart and circulatory physiology 20040401

Title: Hydroxy-methylglutaryl-coenzyme A reductase inhibition improves endothelial dysfunction in type-1 diabetes.

Journal: European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery 20040401

Title: The UCSD Statin Study: a randomized controlled trial assessing the impact of statins on selected noncardiac outcomes.

Journal: Controlled clinical trials 20040401

Title: Effects of grapefruit juice on pharmacokinetics of atorvastatin and pravastatin in Japanese.

Journal: British journal of clinical pharmacology 20040401

Title: Professional athletes suffering from familial hypercholesterolaemia rarely tolerate statin treatment because of muscular problems.

Journal: British journal of clinical pharmacology 20040401

Title: Plasma clearance of human low-density lipoprotein in human apolipoprotein B transgenic mice is related to particle diameter.

Journal: Metabolism: clinical and experimental 20040401

Title: Preventing type II diabetes mellitus.

Journal: Journal of clinical pharmacology 20040401

Title: Effects of pravastatin on lipoproteins and endothelial function in patients receiving human immunodeficiency virus protease inhibitors.

Journal: American heart journal 20040401

Title: Effects of switching statins on achievement of lipid goals: Measuring Effective Reductions in Cholesterol Using Rosuvastatin Therapy (MERCURY I) study.

Journal: American heart journal 20040401

Title: Impaired myocardial vasodilatation during hyperaemic stress is improved by simvastatin but not by pravastatin in patients with hypercholesterolaemia.

Journal: European heart journal 20040401

Title: Pharmacokinetics of flunixin in the cat: enterohepatic circulation and active transport mechanism in the liver.

Journal: Journal of veterinary pharmacology and therapeutics 20040401

Title: American Heart Association scientific sessions.

Journal: Expert opinion on investigational drugs 20040401

Title: Statins and secondary prevention of coronary heart disease.

Journal: British journal of community nursing 20040401

Title: Believe-it then PROVE-IT.

Journal: International journal of clinical practice 20040401

Title: [Lower, lower, lower. The LDL goal value of 200 mg/dl is still much too high].

Journal: MMW Fortschritte der Medizin 20040325

Title: [Results of randomized study: intensive lipid lowering treatment stops coronary atherosclerosis].

Journal: MMW Fortschritte der Medizin 20040325

Title: [Regarding LDL cholesterol: the lower, the better (interview by Dr. Dirk Einecke)].

Journal: MMW Fortschritte der Medizin 20040325

Title: Atorvastatin does not affect the antiplatelet potency of clopidogrel when it is administered concomitantly for 5 weeks in patients with acute coronary syndromes.

Journal: Circulation 20040323

Title: Regulation of geranylgeranyl pyrophosphate synthase in the proliferation of rat FRTL-5 cells: involvement of both cAMP-PKA and PI3-AKT pathways.

Journal: Biochemical and biophysical research communications 20040319

Title: Analysis of pravastatin to prevent recurrence of atrial fibrillation after electrical cardioversion.

Journal: The American journal of cardiology 20040315

Title: Statins inhibit osteoblast migration by inhibiting Rac-Akt signaling.

Journal: Biochemical and biophysical research communications 20040312

Title: Chronic exposure to U18666A induces apoptosis in cultured murine cortical neurons.

Journal: Biochemical and biophysical research communications 20040305

Title: Effect of intensive compared with moderate lipid-lowering therapy on progression of coronary atherosclerosis: a randomized controlled trial.

Journal: JAMA 20040303

Title: High-intensity statin treatment for coronary heart disease.

Journal: JAMA 20040303

Title: The cholesteryl ester transfer protein (CETP) TaqIB polymorphism in the cholesterol and recurrent events study: no interaction with the response to pravastatin therapy and no effects on cardiovascular outcome: a prospective analysis of the CETP TaqIB polymorphism on cardiovascular outcome and interaction with cholesterol-lowering therapy.

Journal: Journal of the American College of Cardiology 20040303

Title: Effects of brassinazole, an inhibitor of brassinosteroid biosynthesis, on light- and dark-grown Chlorella vulgaris.

Journal: Planta 20040301

Title: Verapamil increases the apolipoprotein-mediated release of cellular cholesterol by induction of ABCA1 expression via Liver X receptor-independent mechanism.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20040301

Title: Haemochromatosis gene mutations and risk of coronary heart disease: a west of Scotland coronary prevention study (WOSCOPS) substudy.

Journal: Heart (British Cardiac Society) 20040301

Title: De novo biosynthesis and radiolabeling of mammalian digitalis-like factors.

Journal: Clinical chemistry 20040301

Title: Determination of pravastatin in tablets by capillary electrophoresis.

Journal: Farmaco (Societa chimica italiana : 1989) 20040301

Title: Hypercholesterolemia is common after pediatric heart transplantation: initial experience with pravastatin.

Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20040301

Title: [Effects of angiotensin II receptor blockers, angiotensin converting enzyme inhibitors, 3-hydroxy-3-methyl glutaryl (HMG) CoA reductase inhibitors, amlodipine and epalrestat on cultured basilar artery smooth muscle cell proliferation].

Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20040301

Title: Association of dyslipidemia and effects of statins on nonmacrovascular diseases.

Journal: Clinical therapeutics 20040301

Title: [Clinical study of the month. REVERAL and PROVE-IT: confirmation of the concept ' the lower, the better' for cholesterol therapy in patients with coronary heart disease].

Journal: Revue medicale de Liege 20040301

Title: A boy with autosomal recessive hypercholesterolaemia.

Journal: The Netherlands journal of medicine 20040301

Title: [Interactions of statins with antithrombotic drugs].

Journal: Medizinische Klinik (Munich, Germany : 1983) 20040215

Title: Pravastatin up-regulates transforming growth factor-beta1 in THP-1 human macrophages: effect on scavenger receptor class A expression.

Journal: Biochemical and biophysical research communications 20040213

Title: Synthesis and biological activity of a novel squalene epoxidase inhibitor, FR194738.

Journal: Bioorganic & medicinal chemistry letters 20040209

Title: Statin use and cancer risk in the General Practice Research Database.

Journal: British journal of cancer 20040209

Title: Statins reduce oxidized low-density lipoprotein levels, but do not alter soluble intercellular cell-adhesion molecule-1 and vascular cell-adhesion molecule-1 levels in subjects with hypercholesterolaemia.

Journal: Clinical science (London, England : 1979) 20040201

Title: Functional characterization of pH-sensitive organic anion transporting polypeptide OATP-B in human.

Journal: The Journal of pharmacology and experimental therapeutics 20040201

Title: More Western hypercholesterolemic patients achieve Japan Atherosclerosis Society LDL-C goals with rosuvastatin therapy than with atorvastatin, pravastatin, or simvastatin therapy.

Journal: Circulation journal : official journal of the Japanese Circulation Society 20040201

Title: Statins induce the regression of left ventricular mass in patients with angina.

Journal: Circulation journal : official journal of the Japanese Circulation Society 20040201

Title: Anti-inflammatory and anticoagulant effects of pravastatin in patients with type 2 diabetes.

Journal: Diabetes care 20040201

Title: Acute and chronic regulation of thick ascending limb endothelial nitric oxide synthase by statins.

Journal: Journal of the American Society of Nephrology : JASN 20040201

Title: Effect of rifampicin on pravastatin pharmacokinetics in healthy subjects.

Journal: British journal of clinical pharmacology 20040201

Title: [Role of lipid lowering therapy in patients with peripheral arterial occlusive disease].

Journal: Herz 20040201

Title: Interactions of human- and rat-organic anion transporters with pravastatin and cimetidine.

Journal: Journal of pharmacological sciences 20040201

Title: Clash of the statins? A trial pitting two popular statins against each other helps answer a far more important question: how low should cholesterol go?

Journal: Harvard heart letter : from Harvard Medical School 20040201

Title: Exercise reduces plasma levels of the chemokines MCP-1 and IL-8 in subjects with the metabolic syndrome.

Journal: European heart journal 20040201

Title: Oral anticoagulant drug interactions with statins: case report of fluvastatin and review of the literature.

Journal: Pharmacotherapy 20040201

Title: Diagnostic, clinical, and therapeutic aspects of familial hypercholesterolemia in children.

Journal: Seminars in vascular medicine 20040201

Title: Conceptual foundations of the UCSD Statin Study: a randomized controlled trial assessing the impact of statins on cognition, behavior, and biochemistry.

Journal: Archives of internal medicine 20040126

Title: Atorvastatin: gold standard for prophylaxis of myocardial ischemia and stroke - comparison of the clinical benefit of statins on the basis of randomized controlled endpoint studies.

Journal: European journal of medical research 20040126

Title: Statins potentiate caspase-3 activity in immortalized murine neurons.

Journal: Neuroscience letters 20040123

Title: [Treatment with statins of the elderly].

Journal: Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20040122

Title: Effect of physical activity on serum C-reactive protein.

Journal: The American journal of cardiology 20040115

Title: Additive benefits of pravastatin and aspirin to decrease risks of cardiovascular disease: randomized and observational comparisons of secondary prevention trials and their meta-analyses.

Journal: Archives of internal medicine 20040112

Title: Evidence for a role of human organic anion transporters in the muscular side effects of HMG-CoA reductase inhibitors.

Journal: European journal of pharmacology 20040112

Title: Lovastatin and mevastatin reduce basal and cytokine-stimulated production of prostaglandins from rat microglial cells in vitro: evidence for a mechanism unrelated to the inhibition of hydroxy-methyl-glutaryl CoA reductase.

Journal: Neuroscience letters 20040109

Title: Pravastatin treatment attenuates interstitial inflammation and fibrosis in a rat model of chronic cyclosporine-induced nephropathy.

Journal: American journal of physiology. Renal physiology 20040101

Title: Distinct light-mediated pathways regulate the biosynthesis and exchange of isoprenoid precursors during Arabidopsis seedling development.

Journal: The Plant cell 20040101

Title: Effect of 3-hydroxy-3-methylglutarylcoenzyme A reductase inhibitors (statins) on tissue paraoxonase 1 and plasma platelet activating factor acetylhydrolase activities.

Journal: Journal of cardiovascular pharmacology 20040101

Title: Characterization of uremic toxin transport by organic anion transporters in the kidney.

Journal: Kidney international 20040101

Title: Differential effects of lipid-lowering agents on human cholinesterases.

Journal: Clinical biochemistry 20040101

Title: Interaction between a genetic variant of the platelet fibrinogen receptor and fibrinogen levels in determining the risk of cardiovascular events.

Journal: American heart journal 20040101

Title: Comparisons of effects of statins (atorvastatin, fluvastatin, lovastatin, pravastatin, and simvastatin) on fasting and postprandial lipoproteins in patients with coronary heart disease versus control subjects.

Journal: The American journal of cardiology 20040101

Title: Does statin therapy influence steroid hormone synthesis?

Journal: Zeitschrift fur Kardiologie 20040101

Title: Marked low-density lipoprotein cholesterol reduction below current national cholesterol education program targets provides the greatest reduction in carotid atherosclerosis.

Journal: Clinical cardiology 20040101

Title: Pharmacokinetics and pharmacodynamics of pravastatin in pediatric and adolescent cardiac transplant recipients on a regimen of triple immunosuppression.

Journal: Clinical pharmacology and therapeutics 20040101

Title: Aggressive lipid-lowering regimen halts CHD progression.

Journal: Geriatrics 20040101

Title: Is there a 'best' statin drug?

Journal: The Johns Hopkins medical letter health after 50 20040101

Title: Cholesteryl ester transfer protein concentration is associated with progression of atherosclerosis and response to pravastatin in men with coronary artery disease (REGRESS).

Journal: European journal of clinical investigation 20040101

Title: A cross-media content analysis of motivational themes in direct-to-consumer prescription drug advertising.

Journal: Clinical therapeutics 20040101

Title: Is Lipitor better than Pravachol?

Journal: Health news (Waltham, Mass.) 20040101

Title: Prolonged inadvertent pravastatin use in pregnancy.

Journal: Reproductive toxicology (Elmsford, N.Y.) 20040101

Title: [Statins-a panacea?].

Journal: Zeitschrift fur Kardiologie 20040101

Title: Down-regulating effect of nicotine on connexin43 gap junctions in human umbilical vein endothelial cells is attenuated by statins.

Journal: European journal of cell biology 20040101

Title: Rising statin use and effect on ischemic stroke outcome.

Journal: BMC medicine 20040101

Title: Rosuvastatin: a review of its use in the management of dyslipidemia.

Journal: American journal of cardiovascular drugs : drugs, devices, and other interventions 20040101

Title: C-reactive protein is not only an inflammatory marker but also a direct cause of cardiovascular diseases.

Journal: Medical hypotheses 20040101

Title: Association between the number of coadministered P-glycoprotein inhibitors and serum digoxin levels in patients on therapeutic drug monitoring.

Journal: BMC medicine 20040101

Title: Pravastatin sodium, an inhibitor of HMG-CoA reductase, decreases HDL cholesterol by transfer of cholesteryl ester from HDL to VLDL in Japanese white rabbits.

Journal: Journal of atherosclerosis and thrombosis 20040101

Title: Rosuvastatin-induced arrest in progression of renal disease.

Journal: Cardiology 20040101

Title: Islet transplantation: an update.

Journal: Chang Gung medical journal 20040101

Title: What to do about cholesterol now. Here's the take-home message from startling new research findings.

Journal: Heart advisor 20040101

Title: The influence of statins on the free intracellular calcium concentration in human umbilical vein endothelial cells.

Journal: BMC cardiovascular disorders 20040101

Title: Comparison of urinary excretion of pravastatin and temocapril in bile duct-ligated rats and Eisai hyperbilirubinemic rats (EHBR).

Journal: Journal of hepato-biliary-pancreatic surgery 20040101

Title: Statin therapy in the elderly: observational and randomized controlled trials support event reduction.

Journal: The American journal of geriatric cardiology 20040101

Title: A prospective study of pravastatin in the elderly at risk: new hope for older persons.

Journal: The American journal of geriatric cardiology 20040101

Title: Positive pleiotropic effects of HMG-CoA reductase inhibitor on vitiligo.

Journal: Lipids in health and disease 20040101

Title: Homocysteine and reactive oxygen species in metabolic syndrome, type 2 diabetes mellitus, and atheroscleropathy: the pleiotropic effects of folate supplementation.

Journal: Nutrition journal 20040101

Title: Assessing compliance of cardiologists with the national cholesterol education program (NCEP) III guidelines in an ambulatory care setting.

Journal: Lipids in health and disease 20040101

Title: Approximate equivalent rosuvastatin doses for temporary statin interchange programs.

Journal: The Annals of pharmacotherapy 20040101

Title: [Pravastatin-associated polymyositis, a case report].

Journal: Rinsho shinkeigaku = Clinical neurology 20040101

Title: Statins rise cytoplasmic calcium level [Ca2+]i in cultured endothelial cells.

Journal: Polish journal of pharmacology 20040101

Title: Industrial application of fuzzy control in bioprocesses.

Journal: Advances in biochemical engineering/biotechnology 20040101

Title: Effect of Nandrolone Decanoate on serum lipoprotein (a) and its isoforms in hemodialysis patients.

Journal: Lipids in health and disease 20040101

Title: Pravastatin potentiates the anticoagulant effects of low molecular weight heparin.

Journal: Thrombosis research 20040101

Title: Pravastatin reduced major coronary heart disease (CHD) events in patients with abnormal fasting glucose and a history of CHD.

Journal: ACP journal club 20040101

Title: Statin drugs do not affect serum complement activation in vitro.

Journal: Scandinavian journal of immunology 20040101

Title: Treatment of HCC with pravastatin, octreotide, or gemcitabine--a critical evaluation.

Journal: Hepato-gastroenterology 20040101

Title: Aggressive lowering of low-density lipoprotein cholesterol: do the studies apply to the elderly?

Journal: The American journal of geriatric cardiology 20040101

Title: Mevastatin-induced apoptosis and growth suppression in U266 myeloma cells.

Journal: Anticancer research 20040101

Title: Genetic polymorphisms in cytochrome P450 enzymes: effect on efficacy and tolerability of HMG-CoA reductase inhibitors.

Journal: American journal of cardiovascular drugs : drugs, devices, and other interventions 20040101

Title: Battle of the statins, or how the news media can change patient care.

Journal: JAAPA : official journal of the American Academy of Physician Assistants 20040101

Title: [Interactions between foodstuffs and statins].

Journal: Nutricion hospitalaria 20040101

Title: Enhancing effect of dietary cholesterol and inhibitory effect of pravastatin on allergic pulmonary inflammation.

Journal: Journal of biomedical science 20040101

Title: Disparities in lipid management for African Americans and Caucasians with coronary artery disease: a national cross-sectional study.

Journal: BMC cardiovascular disorders 20040101

Title: [Relationship Between Lipid Lowering and Changes of Hemostasis and Inflammation During Use of Statins in Non-ST Elevation Acute Coronary Syndrome].

Journal: Kardiologiia 20040101

Title: Metabolic cholesterol depletion hinders cell-surface trafficking of the nicotinic acetylcholine receptor.

Journal: Neuroscience 20040101

Title: Interactions between grapefruit juice and cardiovascular drugs.

Journal: American journal of cardiovascular drugs : drugs, devices, and other interventions 20040101

Title: The pivotal role of cholesterol absorption inhibitors in the management of dyslipidemia.

Journal: Lipids in health and disease 20040101

Title: Looking for prognostic information in the ST-T segment--is it really worth it?

Journal: Journal of electrocardiology 20040101

Title: The need for a large-scale trial of fibrate therapy in diabetes: the rationale and design of the Fenofibrate Intervention and Event Lowering in Diabetes (FIELD) study. [ISRCTN64783481].

Journal: Cardiovascular diabetology 20040101

Title: Statins: much more than just a lipid-lowering therapy.

Journal: Indian heart journal 20040101

Title: Efficacy and safety of coadministration of ezetimibe and statins in elderly patients with primary hypercholesterolaemia.

Journal: Drugs & aging 20040101

Title: Atorvastatin and pravastatin elevated pre-heparin lipoprotein lipase mass of type 2 diabetes with hypercholesterolemia.

Journal: Journal of atherosclerosis and thrombosis 20040101

Title: [Mevastatin induced apoptosis in U266 human myeloma cell line].

Journal: Magyar onkologia 20040101

Title: KGF-induced motility of breast cancer cells is dependent on Grb2 and Erk1,2.

Journal: Clinical & experimental metastasis 20040101

Title: [Effect of eprosartan in combination with pravastatin on some parameters of endothelial function in patients with metabolic syndrome.].

Journal: Kardiologiia 20040101

Title: Closing out a large clinical trial: lessons from the prospective study of pravastatin in the elderly at risk (PROSPER).

Journal: Clinical trials (London, England) 20040101

Title: Steady-state pharmacokinetics of pravastatin in children with familial hypercholesterolaemia.

Journal: Clinical drug investigation 20040101

Title: [First comparison of 2 statins shows: only radical LDL lowering stops coronary atherosclerosis].

Journal: MMW Fortschritte der Medizin 20031218

Title: Effect of statins on the progression of bioprosthetic aortic valve degeneration.

Journal: The American journal of cardiology 20031215

Title: [LDL cholesterol in normal range. The lower the better? Implications of the GREACE study].

Journal: MMW Fortschritte der Medizin 20031211

Title: 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors protect cortical neurons from excitotoxicity.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20031203

Title: Lipid lowering by pravastatin increases parasympathetic modulation of heart rate: Galpha(i2), a possible molecular marker for parasympathetic responsiveness.

Journal: Circulation 20031202

Title: Statin-mediated correction of STAT1 signaling and inducible nitric oxide synthase expression in cystic fibrosis epithelial cells.

Journal: American journal of physiology. Lung cellular and molecular physiology 20031201

Title: Proximal tubular cholesterol loading after mitochondrial, but not glycolytic, blockade.

Journal: American journal of physiology. Renal physiology 20031201

Title: Methyl palmitate: a novel product of the Medfly (Ceratitis capitata) corpus allatum.

Journal: Insect biochemistry and molecular biology 20031201

Title: Different effects of simvastatin and pravastatin on adrenal sensitivity to angiotensin II.

Journal: British journal of clinical pharmacology 20031201

Title: Perspectives from the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial--Lipid Lowering Trial and the Anglo-Scandinavian Cardiac Outcomes Trial--Lipid Lowering Arm.

Journal: Current opinion in lipidology 20031201

Title: Antibiotic treatment of atherosclerosis.

Journal: Current opinion in lipidology 20031201

Title: Peroxisome proliferator activated receptor delta genotype in relation to cardiovascular risk factors and risk of coronary heart disease in hypercholesterolaemic men.

Journal: Journal of internal medicine 20031201

Title: Association of Chlamydia pneumoniae antibody with the cholesterol-lowering effect of statins.

Journal: Atherosclerosis 20031201

Title: Effects of atorvastatin and pravastatin on glucose tolerance in diabetic rats mildly induced by streptozotocin.

Journal: Biological & pharmaceutical bulletin 20031201

Title: Effects of pravastatin on cardiomyocyte hypertrophy and ventricular vulnerability in normolipidemic rats after myocardial infarction.

Journal: Journal of molecular and cellular cardiology 20031201

Title: Direct vascular effects of HR780, a novel 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor.

Journal: Clinical and experimental pharmacology & physiology 20031201

Title: Pravastatin decreases cold ischemia--but not alloantigen-dependent transplant arteriosclerosis.

Journal: Transplantation proceedings 20031201

Title: Accuracy of the Australian National Death Index: comparison with adjudicated fatal outcomes among Australian participants in the Long-term Intervention with Pravastatin in Ischaemic Disease (LIPID) study.

Journal: Australian and New Zealand journal of public health 20031201

Title: The next step in cardiovascular protection.

Journal: Atherosclerosis. Supplements 20031201

Title: Long-term statin safety and efficacy in secondary prevention: can combination therapy improve outcomes?

Journal: Atherosclerosis. Supplements 20031201

Title: Preventing the next event in the elderly: the PROSPER perspective.

Journal: Atherosclerosis. Supplements 20031201

Title: [Clinical trials with rosuvastatin: efficacy and safety of its use].

Journal: Italian heart journal : official journal of the Italian Federation of Cardiology 20031201

Title: [Ezetimibe: from pharmacology to clinical trials].

Journal: Annales d'endocrinologie 20031201

Title: Statin face-off. Surprises from the first head-to-head comparison.

Journal: Time 20031124

Title: Effects of imatinib mesylate (STI571, Glivec) on the pharmacokinetics of simvastatin, a cytochrome p450 3A4 substrate, in patients with chronic myeloid leukaemia.

Journal: British journal of cancer 20031117

Title: Usefulness of lowering low-density lipoprotein cholesterol to <70 mg/dl and usefulness of C-reactive protein in patient selection.

Journal: The American journal of cardiology 20031115

Title: Effects of statins on platelet inhibition by a high loading dose of clopidogrel.

Journal: Circulation 20031104

Title: Individual difference in the pharmacokinetics of a drug, pravastatin, in healthy subjects.

Journal: Journal of clinical pharmacology 20031101

Title: Statin therapy: new therapy for cardiac microvascular dysfunction.

Journal: European heart journal 20031101

Title: Benefits of statin treatment in cardiac syndrome-X1.

Journal: European heart journal 20031101

Title: Depression and cardiovascular morbidity and mortality: cause or consequence?

Journal: European heart journal 20031101

Title: Long-term administration of pravastatin reduces serum lipoprotein(a) levels.

Journal: International journal of clinical pharmacology and therapeutics 20031101

Title: Effects of statins on adhesion molecule expression in endothelial cells.

Journal: Journal of thrombosis and haemostasis : JTH 20031101

Title: Ca2+-releasing effect of cerivastatin on the sarcoplasmic reticulum of mouse and rat skeletal muscle fibers.

Journal: Journal of pharmacological sciences 20031101

Title: [Systemic treatment for hepatocellular carcinoma].

Journal: Zentralblatt fur Chirurgie 20031101

Title: Bioconversion of compactin into pravastatin by Streptomyces sp.

Journal: Biotechnology letters 20031101

Title: The cost-effectiveness of a new statin (rosuvastatin) in the UK NHS.

Journal: International journal of clinical practice 20031101

Title: Rhabdomyolysis caused by distigmine bromide.

Journal: Internal medicine (Tokyo, Japan) 20031101

Title: [Pravastatin for older patients with risk of vascular disease. The PROSPER-Study].

Journal: Der Internist 20031101

Title: Pravastatin reduces the incidence of cardiac events among patients with myocardial infarction.

Journal: Japanese heart journal 20031101

Title: Effects of statins on myocardial and coronary artery response to ischemia-reperfusion.

Journal: Canadian journal of physiology and pharmacology 20031101

Title: Rosuvastatin: a new inhibitor of HMG-coA reductase for the treatment of dyslipidemia.

Journal: Expert review of cardiovascular therapy 20031101

Title: p21-dependent inhibition of colon cancer cell growth by mevastatin is independent of inhibition of G1 cyclin-dependent kinases.

Journal: The Journal of biological chemistry 20031031

Title: Rapid effect of 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibition on coronary endothelial function.

Journal: Circulation research 20031031

Title: Pravastatin at 10 mg/day does not decrease plasma levels of either amyloid-beta (Abeta) 40 or Abeta 42 in humans.

Journal: Neuroscience letters 20031030

Title: Effect of pravastatin on coronary plaque volume.

Journal: The American journal of cardiology 20031015

Title: Secondary prevention of cardiovascular events with long-term pravastatin in patients with diabetes or impaired fasting glucose: results from the LIPID trial.

Journal: Diabetes care 20031001

Title: Interleukin-1B genotype modulates the improvement of coronary artery reactivity by lipid-lowering therapy with pravastatin: a placebo-controlled positron emission tomography study in young healthy men.

Journal: Pharmacogenetics 20031001

Title: The bisphosphonate pamidronate is a potent inhibitor of Ewing's sarcoma cell growth in vitro.

Journal: Anti-cancer drugs 20031001

Title: Pravastatin in hyperlipidemia secondary to HIV protease inhibitors without response to fenofibrate: a brief preliminary report.

Journal: Nutrition (Burbank, Los Angeles County, Calif.) 20031001

Title: A polymorphism of the cholesteryl ester transfer protein gene predicts cardiovascular events in non-smokers in the West of Scotland Coronary Prevention Study.

Journal: European heart journal 20031001

Title: Effect of pravastatin on LDL particle concentration as determined by NMR spectroscopy: a substudy of a randomized placebo controlled trial.

Journal: European heart journal 20031001

Title: Effects of eicosapentaenoic acid on cardiovascular events in Japanese patients with hypercholesterolemia: rationale, design, and baseline characteristics of the Japan EPA Lipid Intervention Study (JELIS).

Journal: American heart journal 20031001

Title: Effects of atorvastatin and pravastatin on malondialdehyde-modified LDL in hypercholesterolemic patients.

Journal: Circulation journal : official journal of the Japanese Circulation Society 20031001

Title: The mevalonate synthesis pathway as a therapeutic target in cancer.

Journal: Clinical orthopaedics and related research 20031001

Title: All hydrophobic HMG-CoA reductase inhibitors induce apoptotic death in rat pulmonary vein endothelial cells.

Journal: Atherosclerosis 20031001

Title: Cholesterol oxidase and the hydroxymethylglutaryl coenzyme A reductase inhibitor mevinolin perturb endocytic trafficking in cultured vascular smooth muscle cells.

Journal: Journal of submicroscopic cytology and pathology 20031001

Title: Oxygen free radical release in human failing myocardium is associated with increased activity of rac1-GTPase and represents a target for statin treatment.

Journal: Circulation 20030930

Title: [Is type-2 diabetes mellitus preventable?].

Journal: Orvosi hetilap 20030928

Title: IL-6 is a key factor in growth inhibition of human myeloma cells induced by pravastatin, an HMG-CoA reductase inhibitor.

Journal: International journal of oncology 20030901

Title: Protective effect of fluvastatin, an HMG-CoA reductase inhibitor, on the formation of 8-oxo-2'-deoxyguanosine in the nuclear DNA of hamster pancreas after a single administration of N-nitrosobis(2-oxopropyl)amine.

Journal: Biological & pharmaceutical bulletin 20030901

Title: Lovastatin induces relaxation and inhibits L-type Ca(2+) current in the rat basilar artery.

Journal: Pharmacology & toxicology 20030901

Title: Statins (HMG-CoA reductase inhibitors) reduce CD40 expression in human vascular cells.

Journal: Cardiovascular research 20030901

Title: Pravastatin prevents arrhythmias induced by coronary artery ischemia/reperfusion in anesthetized normocholesterolemic rats.

Journal: Journal of pharmacological sciences 20030901

Title: Statins differ in their ability to block NF-kappaB activation in human blood monocytes.

Journal: International journal of clinical pharmacology and therapeutics 20030901

Title: Regression of an atherosclerotic coronary artery plaque demonstrated by multislice spiral computed tomography in a patient with stable angina pectoris.

Journal: Heart and vessels 20030901

Title: Role of the pharmacist in establishing lipid intervention programs.

Journal: Pharmacotherapy 20030901

Title: Increased expression of plasminogen activator inhibitor-1 by mediators of the acute phase response: a potential progenitor of vasculopathy in hypertensives.

Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20030901

Title: Lack of adverse clopidogrel-atorvastatin clinical interaction from secondary analysis of a randomized, placebo-controlled clopidogrel trial.

Journal: Circulation 20030826

Title: Benefit-risk assessment of Rosuvastatin 10 to 40 milligrams.

Journal: The American journal of cardiology 20030821

Title: Long-chain omega-3 fatty acids from fish reduce sudden cardiac death in patients with coronary heart disease.

Journal: European journal of medical research 20030820

Title: Prospective serial evaluation of myocardial perfusion and lipids during the first six months of pravastatin therapy: coronary artery disease regression single photon emission computed tomography monitoring trial.

Journal: Journal of the American College of Cardiology 20030820

Title: Cloning of an emopamil-binding protein (EBP)-like protein that lacks sterol delta8-delta7 isomerase activity.

Journal: The Biochemical journal 20030815

Title: Syntheses of 3-ethylidenequinuclidine derivatives as squalene synthase inhibitors. Part 2: enzyme inhibition and effects on plasma lipid levels.

Journal: Bioorganic & medicinal chemistry 20030815

Title: Analytical methods for the quantitative determination of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors in biological samples.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20030815

Title: Plasma C-reactive protein as a marker of cardiac allograft vasculopathy in heart transplant recipients.

Journal: Journal of the American College of Cardiology 20030806

Title: Involvement of human organic anion transporting polypeptide OATP-B (SLC21A9) in pH-dependent transport across intestinal apical membrane.

Journal: The Journal of pharmacology and experimental therapeutics 20030801

Title: Pharmacokinetics and pharmacodynamics of pravastatin in children with familial hypercholesterolemia.

Journal: Clinical pharmacology and therapeutics 20030801

Title: Statins: new data in secondary prevention and diabetes. Pravastatin and simvastatin are the best-assessed statins.

Journal: Prescrire international 20030801

Title: Change in the protein level of mevalonate pyrophosphate decarboxylase in tissues of mouse by pravastatin.

Journal: Biological & pharmaceutical bulletin 20030801

Title: Improvement of serum oxidation by pravastatin might be one of the mechanisms by which endothelial function in dilated coronary artery segments is ameliorated.

Journal: Atherosclerosis 20030801

Title: Hypercholesterolemia. The evidence supports use of statins.

Journal: Geriatrics 20030801

Title: Mevastatin suppresses lipopolysaccharide-induced Rac activation in the human monocyte cell line THP-1.

Journal: Surgery 20030801

Title: A comparative study of the in vitro antioxidant activity of statins.

Journal: International journal of cardiology 20030801

Title: Combination of statins and hormone replacement therapy in postmenopausal women is associated with increased bone mineral density.

Journal: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20030801

Title: [Value and role of lipid lowering therapy for cardiovascular prevention in the elderly].

Journal: Annales de cardiologie et d'angeiologie 20030801

Title: [Long-term hypolipidemic treatment of mixed hyperlipidemia with a combination of statins and fibrates].

Journal: Casopis lekaru ceskych 20030801

Title: Metabolic syndrome with and without C-reactive protein as a predictor of coronary heart disease and diabetes in the West of Scotland Coronary Prevention Study.

Journal: Circulation 20030729

Title: Cross-talk between the cytosolic mevalonate and the plastidial methylerythritol phosphate pathways in tobacco bright yellow-2 cells.

Journal: The Journal of biological chemistry 20030718

Title: Effect of pravastatin on intermediate-density and low-density lipoproteins containing apolipoprotein CIII in patients with diabetes mellitus.

Journal: The American journal of cardiology 20030715

Title: Comparison of the efficacy and safety of rosuvastatin versus atorvastatin, simvastatin, and pravastatin across doses (STELLAR* Trial).

Journal: The American journal of cardiology 20030715

Title: Osteoblast-derived oxysterol is a migration-inducing factor for human breast cancer cells.

Journal: The Journal of biological chemistry 20030711

Title: Contribution of organic anion transporter 3 (Slc22a8) to the elimination of p-aminohippuric acid and benzylpenicillin across the blood-brain barrier.

Journal: The Journal of pharmacology and experimental therapeutics 20030701

Title: Obesity and hyperhomocysteinaemia after kidney transplantation.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20030701

Title: The effect of statin therapy on ventricular late potentials in acute myocardial infarction.

Journal: International journal of cardiology 20030701

Title: Pilot study examining the effect of cholesterol lowering on platelet nitric oxide responsiveness and arterial stiffness in subjects with isolated mild hypercholesterolaemia.

Journal: Clinical and experimental pharmacology & physiology 20030701

Title: Acute vasodilator effects of HMG-CoA reductase inhibitors: involvement of PI3-kinase/Akt pathway and Kv channels.

Journal: Journal of cardiovascular pharmacology 20030701

Title: Influence of 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) reductase inhibitors on endothelial nitric oxide synthase and the formation of oxidants in the vasculature.

Journal: Atherosclerosis 20030701

Title: Allocating funds for cardiovascular disease prevention in light of the NCEP ATP III guidelines.

Journal: The American journal of managed care 20030701

Title: Statin-associated memory loss: analysis of 60 case reports and review of the literature.

Journal: Pharmacotherapy 20030701

Title: Antioxidants decreases the intensification of low density lipoprotein in vivo peroxidation during therapy with statins.

Journal: Molecular and cellular biochemistry 20030701

Title: Quantifying effect of statins on low density lipoprotein cholesterol, ischaemic heart disease, and stroke: systematic review and meta-analysis.

Journal: BMJ (Clinical research ed.) 20030628

Title: Correlation of statin-increased platelet APP ratios and reduced blood lipids in AD patients.

Journal: Neurology 20030624

Title: ABCG2 transports sulfated conjugates of steroids and xenobiotics.

Journal: The Journal of biological chemistry 20030620

Title: Beneficial effects of simvastatin and pravastatin on cardiac allograft rejection and survival.

Journal: Journal of the American College of Cardiology 20030604

Title: Contribution of organic anion transporters to the renal uptake of anionic compounds and nucleoside derivatives in rat.

Journal: The Journal of pharmacology and experimental therapeutics 20030601

Title: Pilot study describing the use of pravastatin in pediatric renal transplant recipients.

Journal: Pediatric transplantation 20030601

Title: Effect of pravastatin on loss of renal function in people with moderate chronic renal insufficiency and cardiovascular disease.

Journal: Journal of the American Society of Nephrology : JASN 20030601

Title: Cost effectiveness of statin therapy for the primary prevention of major coronary events in individuals with type 2 diabetes.

Journal: Diabetes care 20030601

Title: Molecular mechanism for inhibition of 3-hydroxy-3-methylglutaryl CoA (HMG-CoA) reductase by rosuvastatin.

Journal: Biochemical Society transactions 20030601

Title: Apo A-I promoter polymorphism influences basal HDL-cholesterol and its response to pravastatin therapy.

Journal: Atherosclerosis 20030601

Title: Biosynthetic maturation of the corpus allatum of the female adult medfly, Ceratitis capitata, and its putative control.

Journal: Journal of insect physiology 20030601

Title: Reduction in serum total cholesterol and risks of coronary events and cerebral infarction in Japanese men: the Kyushu Lipid Intervention Study.

Journal: Circulation journal : official journal of the Japanese Circulation Society 20030601

Title: Antioxidative potential of fluvastatin via the inhibition of nicotinamide adenine dinucleotide phosphate (NADPH) oxidase activity.

Journal: Biological & pharmaceutical bulletin 20030601

Title: The combination of nebivolol plus pravastatin is associated with a more beneficial metabolic profile compared to that of atenolol plus pravastatin in hypertensive patients with dyslipidemia: a pilot study.

Journal: Journal of cardiovascular pharmacology and therapeutics 20030601

Title: Gemfibrozil increases plasma pravastatin concentrations and reduces pravastatin renal clearance.

Journal: Clinical pharmacology and therapeutics 20030601

Title: Polymorphisms of OATP-C (SLC21A6) and OAT3 (SLC22A8) genes: consequences for pravastatin pharmacokinetics.

Journal: Clinical pharmacology and therapeutics 20030601

Title: Collision-induced dissociation of the negative ions of simvastatin hydroxy acid and related species.

Journal: Journal of mass spectrometry : JMS 20030601

Title: Evaluation of the synergistic adverse effects of concomitant therapy with statins and fibrates on rhabdomyolysis.

Journal: The Journal of pharmacy and pharmacology 20030601

Title: Serum lipid comparison in patients treated by statins or fibrates: existence of bad HDL-C responders to statins.

Journal: Acta cardiologica 20030601

Title: Current perspectives on statins.

Journal: Journal of the Indian Medical Association 20030601

Title: Determination of cholesterol-lowering statin drugs in aqueous samples using liquid chromatography-electrospray ionization tandem mass spectrometry.

Journal: Journal of chromatography. A 20030523

Title: [Coronary disease prevention: only the inhibition of inflammation is important. Why lower lipids, too?].

Journal: MMW Fortschritte der Medizin 20030522

Title: Variants of toll-like receptor 4 modify the efficacy of statin therapy and the risk of cardiovascular events.

Journal: Circulation 20030520

Title: Molecular cloning and characterization of CLICK-III/CaMKIgamma, a novel membrane-anchored neuronal Ca2+/calmodulin-dependent protein kinase (CaMK).

Journal: The Journal of biological chemistry 20030516

Title: [HIV-infection, HAART (highly-active antiretroviral therapy) and hyperlipidemia].

Journal: Deutsche medizinische Wochenschrift (1946) 20030509

Title: Cholesterol-modulating agents kill acute myeloid leukemia cells and sensitize them to therapeutics by blocking adaptive cholesterol responses.

Journal: Blood 20030501

Title: LDL containing apolipoprotein CIII is an independent risk factor for coronary events in diabetic patients.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20030501

Title: DD ACE gene polymorphism is associated with increased coronary artery endothelial dysfunction: the PREFACE trial.

Journal: Heart (British Cardiac Society) 20030501

Title: Acute pancreatitis due to pravastatin therapy.

Journal: JOP : Journal of the pancreas 20030501

Title: Different effect induced by treatment with several statins on monocyte tissue factor expression in hypercholesterolemic subjects.

Journal: Clinical and experimental medicine 20030501

Title: Effects of simvastatin and pravastatin on peroxidation of erythrocyte plasma membrane lipids in patients with type 2 hypercholesterolemia.

Journal: Canadian journal of physiology and pharmacology 20030501

Title: [Caution about the use of statins in elderly individuals].

Journal: Revista medica de Chile 20030501

Title: Combination lipid-lowering therapy with statins: safety issues in the postcerivastatin era.

Journal: Expert opinion on drug safety 20030501

Title: Lovastatin and phospholipase Cgamma regulate constitutive and protein kinase C dependent integrin mediated interactions of human T-cells with collagen.

Journal: Cellular immunology 20030501

Title: The future of lipid-lowering therapy: the big picture.

Journal: The Netherlands journal of medicine 20030501

Title: Ezetimibe: a novel option for lowering cholesterol.

Journal: Expert review of cardiovascular therapy 20030501

Title: Statin therapy and small fibre neuropathy: a serial electrophysiological study.

Journal: Journal of the neurological sciences 20030415

Title: Lipid rafts in the maintenance of synapses, dendritic spines, and surface AMPA receptor stability.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20030415

Title: Statins and fibrates for the treatment of hyperlipidaemia in HIV-infected patients receiving HAART.

Journal: AIDS (London, England) 20030411

Title: High-density lipoprotein subpopulations in pathologic conditions.

Journal: The American journal of cardiology 20030403

Title: Role of c-Src in regulation of endothelial nitric oxide synthase expression during exercise training.

Journal: American journal of physiology. Heart and circulatory physiology 20030401

Title: Opposite regulation of the human paraoxonase-1 gene PON-1 by fenofibrate and statins.

Journal: Molecular pharmacology 20030401

Title: The 3-hydroxy-3-methylglutaryl-CoA reductase inhibitor pravastatin reduces disease activity and inflammation in dextran-sulfate induced colitis.

Journal: The Journal of pharmacology and experimental therapeutics 20030401

Title: A defective response to Hedgehog signaling in disorders of cholesterol biosynthesis.

Journal: Nature genetics 20030401

Title: Results of two clinical trials on the safety and efficacy of pravastatin 80 and 160 mg per day.

Journal: The American journal of cardiology 20030401

Title: Effect of pravastatin on cardiovascular events and mortality in 1516 women with coronary heart disease: results from the Long-Term Intervention with Pravastatin in Ischemic Disease (LIPID) study.

Journal: American heart journal 20030401

Title: Reduction in levels of 24S-hydroxycholesterol by statin treatment in patients with Alzheimer disease.

Journal: Archives of neurology 20030401

Title: The power of statins: aggressive lipid lowering.

Journal: Clinical cardiology 20030401

Title: Lipid-lowering therapy and risk of coronary events.

Journal: JAMA 20030401

Title: Lipid-lowering therapy and risk of coronary events.

Journal: JAMA 20030401

Title: Lipid-lowering therapy and risk of coronary events.

Journal: JAMA 20030401

Title: Efficacy and safety of ezetimibe coadministered with pravastatin in patients with primary hypercholesterolemia: a prospective, randomized, double-blind trial.

Journal: European heart journal 20030401

Title: Effects of cholesterol-lowering therapy on pressor hyperreactivity to stress in hypercholesterolemic patients.

Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20030401

Title: Uptake of rosuvastatin by isolated rat hepatocytes: comparison with pravastatin.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20030401

Title: More on PROSPER.

Journal: Lancet (London, England) 20030329

Title: More on PROSPER.

Journal: Lancet (London, England) 20030329

Title: Safety and statin therapy: reconsidering the risks and benefits.

Journal: Archives of internal medicine 20030324

Title: Differential effects of lipid-lowering therapies on stroke prevention: a meta-analysis of randomized trials.

Journal: Archives of internal medicine 20030324

Title: Mevastatin can cause G1 arrest and induce apoptosis in pulmonary artery smooth muscle cells through a p27Kip1-independent pathway.

Journal: Circulation research 20030321

Title: The sorry saga of the statins in New Zealand--pharmacopolitics versus patient care.

Journal: The New Zealand medical journal 20030314

Title: [Fewer myocardial infarcts. Statin therapy is even effective in the elderly].

Journal: MMW Fortschritte der Medizin 20030313

Title: Inhibition of paclitaxel and baccatin III accumulation by mevinolin and fosmidomycin in suspension cultures of Taxus baccata.

Journal: Journal of biotechnology 20030306

Title: Efficacy of rosuvastatin compared with other statins at selected starting doses in hypercholesterolemic patients and in special population groups.

Journal: The American journal of cardiology 20030306

Title: Guidelines for lowering lipids to reduce coronary artery disease risk: a comparison of rosuvastatin with atorvastatin, pravastatin, and simvastatin for achieving lipid-lowering goals.

Journal: The American journal of cardiology 20030306

Title: Lipid and apolipoprotein ratios: association with coronary artery disease and effects of rosuvastatin compared with atorvastatin, pravastatin, and simvastatin.

Journal: The American journal of cardiology 20030306

Title: Effects of bezafibrate and pravastatin on remnant-like lipoprotein particles and lipoprotein subclasses in type 2 diabetes.

Journal: Diabetes research and clinical practice 20030301

Title: Non-high-density lipoprotein cholesterol: a target of lipid-lowering in dialysis patients.

Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 20030301

Title: Statin effects on cholesterol micro-domains in brain plasma membranes.

Journal: Biochemical pharmacology 20030301

Title: Treating dyslipidemia with statins: the risk-benefit profile.

Journal: American heart journal 20030301

Title: Statins inhibit high glucose-mediated neutrophil-endothelial cell adhesion through decreasing surface expression of endothelial adhesion molecules by stimulating production of endothelial nitric oxide.

Journal: Microvascular research 20030301

Title: High praise for an old standby. Low-cost diuretics excel in combating high blood pressure.

Journal: Heart advisor 20030301

Title: Pravastatin protection from cold stress in myocardium of rats.

Journal: Japanese heart journal 20030301

Title: [Cardiac rehabilitation in a HIV-patient treated with protease inhibitors].

Journal: Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace 20030301

Title: Prevention of nitrate tolerance by long-term treatment with statins.

Journal: Cardiovascular drugs and therapy 20030301

Title: [Statin treatment in type 2 diabetes. Is it a must today?].

Journal: MMW Fortschritte der Medizin 20030227

Title: Reduced connexin43 expression inhibits atherosclerotic lesion formation in low-density lipoprotein receptor-deficient mice.

Journal: Circulation 20030225

Title: [After several years of statin therapy. Long-term prevention of cardiac death].

Journal: MMW Fortschritte der Medizin 20030220

Title: Pharmacologic plaque passivation for the reduction of recurrent cardiac events in acute coronary syndromes.

Journal: Journal of the American College of Cardiology 20030219

Title: Inhibition of cdk2 activating phosphorylation by mevastatin.

Journal: The Journal of biological chemistry 20030214

Title: Trafficking of cholesterol from cell bodies to distal axons in Niemann Pick C1-deficient neurons.

Journal: The Journal of biological chemistry 20030207

Title: Mevastatin can increase toxicity in primary AMLs exposed to standard therapeutic agents, but statin efficacy is not simply associated with ras hotspot mutations or overexpression.

Journal: Leukemia research 20030201

Title: Increased levels of asymmetric dimethylarginine in populations at risk for atherosclerotic disease. Effects of pravastatin.

Journal: Atherosclerosis 20030201

Title: Does pravastatin affect circulating levels of soluble TNF receptor 2 in hypercholesterolemic patients?

Journal: Atherosclerosis 20030201

Title: Pravastatin inhibits pro-inflammatory effects of Alzheimer's peptide Abeta(1-42) in glioma cell culture in vitro.

Journal: Pharmacological research 20030201

Title: Levels of adhesion molecules do not decrease after 3 months of statin therapy in moderate hypercholesterolaemia.

Journal: Clinical science (London, England : 1979) 20030201

Title: The PROSPER trial.

Journal: Lancet (London, England) 20030201

Title: The PROSPER trial.

Journal: Lancet (London, England) 20030201

Title: The PROSPER trial.

Journal: Lancet (London, England) 20030201

Title: The PROSPER trial.

Journal: Lancet (London, England) 20030201

Title: The PROSPER trial.

Journal: Lancet (London, England) 20030201

Title: Inhibitor studies of isopentenyl pyrophosphate biosynthesis in suspension cultures of the yew Taxus chinensis var. mairei.

Journal: Biotechnology and applied biochemistry 20030201

Title: Effect of atorvastatin and pravastatin on serum C-reactive protein.

Journal: American heart journal 20030201

Title: Muscular adverse effects of statins.

Journal: Prescrire international 20030201

Title: Statins can inhibit proliferation of human breast cancer cells in vitro.

Journal: Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 20030201

Title: Statin fails to meet expectations.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20030201

Title: Comparison of the effect of two HMG CoA reductase inhibitors on LDL susceptibility to oxidation.

Journal: Arquivos brasileiros de cardiologia 20030201

Title: Modulation of the inflammatory process by statins.

Journal: Drugs of today (Barcelona, Spain : 1998) 20030201

Title: Alcohol consumption and plasma concentration of C-reactive protein.

Journal: Circulation 20030128

Title: Pravastatin for secondary prevention of cardiovascular events in persons with mild chronic renal insufficiency.

Journal: Annals of internal medicine 20030121

Title: Summaries for patients. Treating cholesterol in patients with mild kidney disease.

Journal: Annals of internal medicine 20030121

Title: Atorvastatin reduces the ability of clopidogrel to inhibit platelet aggregation: a new drug-drug interaction.

Journal: Circulation 20030107

Title: Transformations of cyclic nonaketides by Aspergillus terreus mutants blocked for lovastatin biosynthesis at the lovA and lovC genes.

Journal: Organic & biomolecular chemistry 20030107

Title: High-performance liquid chromatography coupled with negative ion tandem mass spectrometry for determination of pravastatin in human plasma.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20030105

Title: Comparison of micronized fenofibrate and pravastatin in patients with primary hyperlipidemia.

Journal: Journal of cardiovascular pharmacology 20030101

Title: Statins regulate alpha2beta1-integrin expression and collagen I-dependent functions in human vascular smooth muscle cells.

Journal: Journal of cardiovascular pharmacology 20030101

Title: Statin therapy in the elderly-the evidence mounts.

Journal: The American journal of geriatric cardiology 20030101

Title: The ability of statins to inhibit bone resorption is directly related to their inhibitory effect on HMG-CoA reductase activity.

Journal: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20030101

Title: Cerivastatin and atorvastatin inhibit IL-3-dependent differentiation and IgE-mediated histamine release in human basophils and downmodulate expression of the basophil-activation antigen CD203c/E-NPP3.

Journal: Journal of leukocyte biology 20030101

Title: Ubiquinone does not rescue acute myeloid leukemia cells from growth inhibition by statins.

Journal: Leukemia 20030101

Title: Drug-induced, Ro/SSA-positive cutaneous lupus erythematosus.

Journal: Archives of dermatology 20030101

Title: Comparing HMG-CoA reductase inhibitors.

Journal: Clinical cardiology 20030101

Title: Treating hypercholesterolemia: looking forward.

Journal: Clinical cardiology 20030101

Title: Implementing guidelines in primary care: can population impact measures help?

Journal: BMC public health 20030101

Title: hsCRP and HDL effects of statins trial (CHEST): rapid effect of statin therapy on C-reactive protein and high-density lipoprotein levels A clinical investigation.

Journal: Heart disease (Hagerstown, Md.) 20030101

Title: Rosuvastatin: a new HMG-CoA reductase inhibitor for the treatment of hypercholesterolemia.

Journal: Heart disease (Hagerstown, Md.) 20030101

Title: Influence of diabetes mellitus on heart failure risk and outcome.

Journal: Cardiovascular diabetology 20030101

Title: Interactions between cyclosporin and lipid-lowering drugs: implications for organ transplant recipients.

Journal: Drugs 20030101

Title: The development of combination drugs for atherosclerosis.

Journal: Current atherosclerosis reports 20030101

Title: Hepatobiliary transport of a nonpeptidic endothelin antagonist, (+)-(5S,6R,7R)-2-butyl-7-[2((2S)-2-carboxypropyl)-4-methoxyphenyl]-5-(3,4-methylenedioxyphenyl) cyclopentenol[1,2-b]pyridine-6-carboxylic acid: uptake by isolated rat hepatocytes and canalicular membrane vesicles.

Journal: Pharmaceutical research 20030101

Title: Preventing angiographic progression of coronary atherosclerosis with pravastatin.

Journal: Journal of atherosclerosis and thrombosis 20030101

Title: Statin therapy in the elderly: does it make good clinical and economic sense?

Journal: Drugs & aging 20030101

Title: [Clinical study of the month. The ALLHAT-LLT trial].

Journal: Revue medicale de Liege 20030101

Title: A model to assess the cost effectiveness of statins in achieving the UK National Service Framework target cholesterol levels.

Journal: PharmacoEconomics 20030101

Title: An economic analysis of the Atorvastatin Comparative Cholesterol Efficacy and Safety Study (ACCESS).

Journal: PharmacoEconomics 20030101

Title: Statins stimulate arachidonic acid release and prostaglandin I2 production in rat liver cells.

Journal: Lipids in health and disease 20030101

Title: Pravastatin benefits elderly patients: results of PROSPER study.

Journal: Cardiovascular journal of South Africa : official journal for Southern Africa Cardiac Society [and] South African Society of Cardiac Practitioners 20030101

Title: LIFE and ARBITER.

Journal: Preventive cardiology 20030101

Title: Variable influence of statins on isoprostanes in hyperlipidemia.

Journal: Advances in experimental medicine and biology 20030101

Title: Twice-daily amprenavir 1200 mg versus amprenavir 600 mg/ritonavir 100 mg, in combination with at least 2 other antiretroviral drugs, in HIV-1-infected patients.

Journal: BMC infectious diseases 20030101

Title: [Drug interactions with antilipemics].

Journal: Therapie 20030101

Title: Put your heart into the joint benefits of statins!

Journal: Arthritis research & therapy 20030101

Title: HMG-CoA reductase inhibitors inhibit inducible nitric oxide synthase gene expression in macrophages.

Journal: Journal of biomedical science 20030101

Title: Rosuvastatin--a highly effective new 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor: review of clinical trial data at 10-40 mg doses in dyslipidemic patients.

Journal: Cardiology 20030101

Title: Pravastatin lowered coronary disease risk in elderly persons with or at risk for vascular disease.

Journal: ACP journal club 20030101

Title: Pravastatin was not better than usual care in reducing all-cause mortality or CHD events.

Journal: ACP journal club 20030101

Title: Potential nontraditional applications of statins.

Journal: The Annals of pharmacotherapy 20030101

Title: Effect of statins combined with estradiol on the proliferation of human receptor-positive and receptor-negative breast cancer cells.

Journal: Menopause (New York, N.Y.) 20030101

Title: HMG-CoA reductase inhibition aborts functional differentiation and triggers apoptosis in cultured primary human monocytes: a potential mechanism of statin-mediated vasculoprotection.

Journal: BMC cardiovascular disorders 20030101

Title: HIV protease inhibitors and dyslipidemia.

Journal: AIDS reviews 20030101

Title: [Markers of inflammation and platelet aggregation in patients with non ST elevation acute coronary syndrome treated with atorvastatin or pravastatin].

Journal: Kardiologiia 20030101

Title: [Non ST elevation acute coronary syndrome: early use of pravastatin or atorvastatin is associated with divergent changes of parameters of hemostasis].

Journal: Kardiologiia 20030101

Title: Gastrointestinal cancer and the long-term use of pravastatin in the elderly.

Journal: Acta oncologica (Stockholm, Sweden) 20030101

Title: Rosuvastatin achieves new standards in lipid management.

Journal: Cardiovascular journal of South Africa : official journal for Southern Africa Cardiac Society [and] South African Society of Cardiac Practitioners 20030101

Title: Cholesterol-lowering action of policosanol compares well to that of pravastatin and lovastatin.

Journal: Cardiovascular journal of South Africa : official journal for Southern Africa Cardiac Society [and] South African Society of Cardiac Practitioners 20030101

Title: A review of anabolic therapies for osteoporosis.

Journal: Arthritis research & therapy 20030101

Title: [Pharmacologic characteristics of rosuvastatin, a new HMG-CoA reductase inhibitor].

Journal: Therapie 20030101

Title: Clinical pharmacokinetics of statins.

Journal: Methods and findings in experimental and clinical pharmacology 20030101

Title: [Primary prevention of stroke. What helps--what does not help? The guidelines of the German Society of Neurology briefly summarized].

Journal: MMW Fortschritte der Medizin 20030101

Title: Home-based versus hospital-based cardiac rehabilitation after myocardial infarction or revascularisation: design and rationale of the Birmingham Rehabilitation Uptake Maximisation Study (BRUM): a randomised controlled trial [ISRCTN72884263].

Journal: BMC cardiovascular disorders 20030101

Title: [Results of clinical evidence: Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT)].

Journal: Kardiologiia 20030101

Title: Molecular regulation of cholesterol biosynthesis: implications in carcinogenesis.

Journal: Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 20030101

Title: Pharmacological comparison of the statins.

Journal: Arzneimittel-Forschung 20030101

Title: Cerivastatin ameliorates high insulin-enhanced neutrophil-endothelial cell adhesion and endothelial intercellular adhesion molecule-1 expression by inhibiting mitogen-activated protein kinase activation.

Journal: Journal of diabetes and its complications 20030101

Title: Platelet-neutrophil conjugate formation is increased in diabetic women with cardiovascular disease.

Journal: Cardiovascular diabetology 20030101

Title: Are statins indicated for the primary prevention of coronary heart disease in octogenarians? protagonist viewpoint.

Journal: The American journal of geriatric cardiology 20030101

Title: Ezetimibe: a first-in-class, novel cholesterol absorption inhibitor.

Journal: Cardiovascular drug reviews 20030101

Title: Statin stimulates bone morphogenetic protein-2, aggrecan, and type 2 collagen gene expression and proteoglycan synthesis in rat chondrocytes.

Journal: Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association 20030101

Title: Pravastatin: a review of its use in elderly patients.

Journal: Drugs & aging 20030101

Title: Differential effects of fenofibrate versus atorvastatin on the concentrations of E-selectin and vascular cellular adhesion molecule-1 in patients with type 2 diabetes mellitus and mixed hyperlipoproteinemia: a randomized cross-over trial.

Journal: Cardiovascular diabetology 20030101

Title: Ultrastructure of mouse striated muscle fibers following pravastatin administration.

Journal: Journal of muscle research and cell motility 20030101

Title: What ALLHAT tells us about treating high-risk patients with hypertension and hyperlipidemia.

Journal: The Journal of cardiovascular nursing 20030101

Title: Hypergravity-induced changes in gene expression in Arabidopsis hypocotyls.

Journal: Advances in space research : the official journal of the Committee on Space Research (COSPAR) 20030101

Title: Comparison of the efficacy of rosuvastatin versus atorvastatin, simvastatin, and pravastatin in achieving lipid goals: results from the STELLAR trial.

Journal: Current medical research and opinion 20030101

Title: Characteristics and lipid distribution of a large, high-risk, hypertensive population: the lipid-lowering component of the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT).

Journal: Journal of clinical hypertension (Greenwich, Conn.) 20030101

Title: Statins lower plasma and lymphocyte ubiquinol/ubiquinone without affecting other antioxidants and PUFA.

Journal: BioFactors (Oxford, England) 20030101

Title: Ezetimibe.

Journal: American journal of cardiovascular drugs : drugs, devices, and other interventions 20030101

Title: Monocyte chemoattractant protein-1 and CC-chemokine receptor-2 in severe hypercholesterolaemia.

Journal: Scandinavian journal of clinical and laboratory investigation 20030101

Title: Statins in hypercholesterolaemia: a dose-specific meta-analysis of lipid changes in randomised, double blind trials.

Journal: BMC family practice 20030101

Title: Plasma asymmetric dimethylarginine modifies the effect of pravastatin on myocardial blood flow in young adults.

Journal: Vascular medicine (London, England) 20030101

Title: Uptake mechanism of pitavastatin, a new inhibitor of HMG-CoA reductase, in rat hepatocytes.

Journal: Drug metabolism and pharmacokinetics 20030101

Title: Simvastatin and pravastatin equally improve flow-mediated dilation in males with hypercholesterolemia.

Journal: Wiener klinische Wochenschrift 20021230

Title: Receptor-dependent regulation of the CYP3A4 gene.

Journal: Toxicology 20021227

Title: Toxicological implications of hepatobiliary transporters.

Journal: Toxicology 20021227

Title: Secretion of apolipoprotein E by brain glia requires protein prenylation and is suppressed by statins.

Journal: Brain research 20021220

Title: Major outcomes in moderately hypercholesterolemic, hypertensive patients randomized to pravastatin vs usual care: The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT-LLT).

Journal: JAMA 20021218

Title: The ALLHAT lipid lowering trial--less is less.

Journal: JAMA 20021218

Title: Chelation-controlled reduction: stereoselective formation of syn-1,3-diols and synthesis of compactin and mevinolin lactone.

Journal: The Journal of organic chemistry 20021213

Title: Protecting the heart: a practical review of the statin studies.

Journal: MedGenMed : Medscape general medicine 20021210

Title: [Even in advanced age: statins prevent infarct].

Journal: MMW Fortschritte der Medizin 20021205

Title: [Statins for all seniors?].

Journal: MMW Fortschritte der Medizin 20021205

Title: Regulation of CYP2B6 and CYP3A expression by hydroxymethylglutaryl coenzyme A inhibitors in primary cultured human hepatocytes.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20021201

Title: Association of pravastatin and left ventricular mass in hypercholesterolemic patients: role of 8-iso-prostaglandin f2alpha formation.

Journal: Journal of cardiovascular pharmacology 20021201

Title: Fluvastatin induces apoptosis in rat neonatal cardiac myocytes: a possible mechanism of statin-attenuated cardiac hypertrophy.

Journal: Journal of cardiovascular pharmacology 20021201

Title: [Comparative study of the impact of diet versus pravastatin on color vision in Brodman area 19 detected by computerized chromatic analysis (CARDIOCOLOUR Study)].

Journal: Revista espanola de cardiologia 20021201

Title: Statin inhibits leukocyte-endothelial interaction and prevents neuronal death induced by ischemia-reperfusion injury in the rat retina.

Journal: Archives of ophthalmology (Chicago, Ill. : 1960) 20021201

Title: Risk factors for non-haemorrhagic stroke in patients with coronary heart disease and the effect of lipid-modifying therapy with pravastatin.

Journal: Journal of hypertension 20021201

Title: Targeting cardiovascular risk associated with both low density and high density lipoproteins using statin-niacin combination therapy.

Journal: Journal of cardiovascular risk 20021201

Title: Endothelial nitric oxide synthase genotype modulates the improvement of coronary blood flow by pravastatin: a placebo-controlled PET study.

Journal: Journal of molecular medicine (Berlin, Germany) 20021201

Title: Management of dyslipidemia in the high-risk patient.

Journal: American heart journal 20021201

Title: Efficacy and safety of rosuvastatin compared with pravastatin and simvastatin in patients with hypercholesterolemia: a randomized, double-blind, 52-week trial.

Journal: American heart journal 20021201

Title: Inhibition of cholesterol synthesis causes both hypercholesterolemia and hypocholesterolemia in hamsters.

Journal: Biological & pharmaceutical bulletin 20021201

Title: Statins do not meet expectations for lowering low-density lipoprotein cholesterol levels when used in clinical practice.

Journal: The American journal of medicine 20021201

Title: Measuring the cost-effectiveness of lipid-lowering drugs in the elderly: the outcomes research and economic analysis components of the PROSPER trial.

Journal: Controlled clinical trials 20021201

Title: Time-dependent effect of statins on platelet function in hypercholesterolaemia.

Journal: European journal of clinical investigation 20021201

Title: Chlamydiae host cell interactions revealed using DNA microarrays.

Journal: Annals of the New York Academy of Sciences 20021201

Title: An examination of the effect of cytochrome P450 drug interactions of hydroxymethylglutaryl-coenzyme A reductase inhibitors on health care utilization: a Canadian population-based study.

Journal: Clinical therapeutics 20021201

Title: Enzyme inhibitors to increase poly-3-hydroxybutyrate production by transgenic tobacco.

Journal: Bioscience, biotechnology, and biochemistry 20021201

Title: Differing effects of low-dose estrogen-progestin therapy and pravastatin in postmenopausal hypercholesterolemic women.

Journal: Climacteric : the journal of the International Menopause Society 20021201

Title: [The PROSPER Study (PROspective study of pravastatin in the elderly at risk)].

Journal: Revue medicale de Liege 20021201

Title: Toward a role for statins in immunomodulation.

Journal: Molecular interventions 20021201

Title: [Treatment with statins: further data from the Heart Protection Study].

Journal: Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20021130

Title: Statin-induced myositis migrans.

Journal: Wiener klinische Wochenschrift 20021130

Title: High-risk elderly patients PROSPER from cholesterol-lowering therapy.

Journal: Lancet (London, England) 20021123

Title: Pravastatin in elderly individuals at risk of vascular disease (PROSPER): a randomised controlled trial.

Journal: Lancet (London, England) 20021123

Title: Contribution of the mevalonate and methylerythritol phosphate pathways to the biosynthesis of gibberellins in Arabidopsis.

Journal: The Journal of biological chemistry 20021122

Title: Comparative beneficial effects of simvastatin and pravastatin on cardiac allograft rejection and survival.

Journal: Journal of the American College of Cardiology 20021106

Title: Regulation of interleukin-8 expression by HMG-CoA reductase inhibitors in human vascular smooth muscle cells.

Journal: Atherosclerosis 20021101

Title: Association of the factor XII 46C>T polymorphism with risk of coronary heart disease (CHD) in the WOSCOPS study.

Journal: Atherosclerosis 20021101

Title: Association of factor VII levels with inflammatory parameters in hypercholesterolemic patients.

Journal: Atherosclerosis 20021101

Title: Beyond lipid lowering: the role of statins in vascular protection.

Journal: International journal of cardiology 20021101

Title: Liver-specific distribution of rosuvastatin in rats: comparison with pravastatin and simvastatin.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20021101

Title: Squalestatin 1-inducible expression of rat CYP2B: evidence that an endogenous isoprenoid is an activator of the constitutive androstane receptor.

Journal: Molecular pharmacology 20021101

Title: Early statin therapy for acute coronary syndromes.

Journal: The Annals of pharmacotherapy 20021101

Title: Role of the cholesterol biosynthetic pathway in osteoblastic differentiation of marrow stromal cells.

Journal: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20021101

Title: Plasminogen activator inhibitor-1: physiologic role, regulation, and the influence of common pharmacologic agents.

Journal: Journal of clinical pharmacology 20021101

Title: 3-hydroxy-3-methylglutaryl coenzyme A reductase-independent inhibition of CD40 expression by atorvastatin in human endothelial cells.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20021101

Title: Functional analysis of mlcR, a regulatory gene for ML-236B (compactin) biosynthesis in Penicillium citrinum.

Journal: Molecular genetics and genomics : MGG 20021101

Title: Zeroing in on how low cholesterol should go.

Journal: Heart advisor 20021101

Title: Pravastatin promotes coronary collateral circulation in patients with coronary artery disease.

Journal: Coronary artery disease 20021101

Title: Preclinical pharmacokinetics of statins.

Journal: Methods and findings in experimental and clinical pharmacology 20021101

Title: Cerivastatin, a hydroxymethylglutaryl coenzyme A reductase inhibitor, inhibits cardiac myocyte hypertrophy induced by endothelin.

Journal: European journal of pharmacology 20021025

Title: Cholesterol-lowering therapy with pravastatin in patients with average cholesterol levels and established ischaemic heart disease: is it cost-effective?

Journal: The Medical journal of Australia 20021021

Title: Low-density lipoprotein lowering and atherosclerosis progression: does more mean less?

Journal: Circulation 20021015

Title: ARBITER: Arterial Biology for the Investigation of the Treatment Effects of Reducing Cholesterol: a randomized trial comparing the effects of atorvastatin and pravastatin on carotid intima medial thickness.

Journal: Circulation 20021015

Title: The lower the LDL, the better.

Journal: Circulation 20021015

Title: Comparing the effects of five different statins on the HDL subpopulation profiles of coronary heart disease patients.

Journal: Atherosclerosis 20021001

Title: A cell-based reporter gene assay for determining induction of CYP3A4 in a high-volume system.

Journal: The Journal of pharmacology and experimental therapeutics 20021001

Title: Testing cognitive function in elderly populations: the PROSPER study. PROspective Study of Pravastatin in the Elderly at Risk.

Journal: Journal of neurology, neurosurgery, and psychiatry 20021001

Title: Statins, 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors, are able to reduce superoxide anion production by NADPH oxidase in THP-1-derived monocytes.

Journal: Journal of cardiovascular pharmacology 20021001

Title: Factors affecting low-density lipoprotein and high-density lipoprotein cholesterol response to pravastatin in the West Of Scotland Coronary Prevention Study (WOSCOPS).

Journal: The American journal of cardiology 20021001

Title: Frequency of new coronary events in older persons with peripheral arterial disease and serum low-density lipoprotein cholesterol > or = 125 mg/dl treated with statins versus no lipid-lowering drug.

Journal: The American journal of cardiology 20021001

Title: Severe rhabdomyolysis after laparoscopic surgery for adenocarcinoma of the rectum in two patients treated with statins.

Journal: Anesthesiology 20021001

Title: Statin lipid-lowering therapy for acute myocardial infarction and unstable angina: efficacy and mechanism of benefit.

Journal: Mayo Clinic proceedings 20021001

Title: Plasma membrane cholesterol controls the cytotoxicity of Alzheimer's disease AbetaP (1-40) and (1-42) peptides.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20021001

Title: Antioxidative effects of fluvastatin and its metabolites against DNA damage in streptozotocin-treated mice.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20021001

Title: Evaluation and management of dyslipidemia in patients with HIV infection.

Journal: Journal of general internal medicine 20021001

Title: Pharmacokinetics of pravastatin in heart-transplant patients taking cyclosporin A.

Journal: International journal of clinical pharmacology and therapeutics 20021001

Title: Clinical inquiries. What is the target for low-density lipoprotein cholesterol in patients with heart disease?

Journal: The Journal of family practice 20021001

Title: [A survey on the status of lipid-lowering therapy in 180 hypercholesterolemic patients].

Journal: Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi 20021001

Title: Prevention of chronic rejection by pravastatin in a rat kidney transplant model.

Journal: Transplantation 20020927

Title: Reducing the risk for stroke in patients with myocardial infarction: a Myocardial Ischemia Reduction with Aggressive Cholesterol Lowering (MIRACL) substudy.

Journal: Circulation 20020924

Title: Lipid modification of proteins in Archaea: attachment of a mevalonic acid-based lipid moiety to the surface-layer glycoprotein of Haloferax volcanii follows protein translocation.

Journal: The Biochemical journal 20020915

Title: Statin treatment following coronary artery stenting and one-year survival.

Journal: Journal of the American College of Cardiology 20020904

Title: Clinical implications of statin event trials.

Journal: Current atherosclerosis reports 20020901

Title: Mechanisms of NOS2 regulation by Rho GTPase signaling in airway epithelial cells.

Journal: American journal of physiology. Lung cellular and molecular physiology 20020901

Title: Effects of phalloidin on the biliary excretion of cholephilic compounds in rats.

Journal: Pharmacology 20020901

Title: Effects of pravastatin sodium on mevalonate metabolism in common marmosets.

Journal: Journal of biochemistry 20020901

Title: A review of the pharmacologic and pharmacokinetic aspects of rosuvastatin.

Journal: Journal of clinical pharmacology 20020901

Title: Update on the management of dyslipidemia.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20020901

Title: Japanese familial hypercholesterolaemia with a 327insC mutation in the LDL receptor gene.

Journal: Annals of clinical biochemistry 20020901

Title: Statins reduce inflammation in atheroma of nonhuman primates independent of effects on serum cholesterol.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20020901

Title: [Utility of pravastin in cardiac transplant dyslipidemia].

Journal: Revista clinica espanola 20020901

Title: Effect of increased dosage of the ML-236B (compactin) biosynthetic gene cluster on ML-236B production in Penicillium citrinum.

Journal: Molecular genetics and genomics : MGG 20020901

Title: Management of dyslipidemia in the primary prevention of coronary heart disease.

Journal: Current opinion in cardiology 20020901

Title: [Primary prevention of diabetes mellitus by pharmacological intervention].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20020901

Title: Massive postoperative rhabdomyolysis following combined CABG/abdominal aortic replacement: a possible association with HMG-CoA reductase inhibitors.

Journal: Cardiovascular drugs and therapy 20020901

Title: [Antilipemic agents in combined therapy].

Journal: Orvosi hetilap 20020825

Title: Pravastatin and Aspirin.

Journal: Circulation 20020806

Title: Sex difference in inhibition of in vitro mexazolam metabolism by various 3-hydroxy-3-methylglutaryl-coenzyme a reductase inhibitors in rat liver microsomes.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20020801

Title: Chronic hydroxymethylglutaryl coenzyme a reductase inhibition and endothelial function of the normocholesterolemic rat: comparison with angiotensin-converting enzyme inhibition.

Journal: Journal of cardiovascular pharmacology 20020801

Title: Pravastatin does not alter protease inhibitor exposure or virologic efficacy during a 24-week period of therapy.

Journal: Journal of acquired immune deficiency syndromes (1999) 20020801

Title: Reduction of bFGF-induced smooth muscle cell proliferation and endothelin receptor mRNA expression by mevastatin and atorvastatin.

Journal: Biochemical pharmacology 20020801

Title: Pharmacology of 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors (statins), including rosuvastatin and pitavastatin.

Journal: Journal of clinical pharmacology 20020801

Title: HMG-CoA reductase inhibition and PPAR- alpha activation both inhibit cyclosporin A induced endothelin-1 secretion in cultured endothelial cells.

Journal: Clinical science (London, England : 1979) 20020801

Title: The potential of pill splitting to achieve cost savings.

Journal: The American journal of managed care 20020801

Title: Early use of pravastatin in patients with acute myocardial infarction undergoing coronary angioplasty.

Journal: Acta cardiologica 20020801

Title: The HMG Co-A reductase inhibitors ('statins') and myotoxic effects.

Journal: South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 20020801

Title: The extent of late in-stent neointima formation is modified by treatment with pravastatin: a preliminary study with intravascular ultrasound.

Journal: Italian heart journal : official journal of the Italian Federation of Cardiology 20020801

Title: Association between enhanced soluble CD40L and prothrombotic state in hypercholesterolemia: effects of statin therapy.

Journal: Circulation 20020723

Title: Relations of lipoprotein subclass levels and low-density lipoprotein size to progression of coronary artery disease in the Pravastatin Limitation of Atherosclerosis in the Coronary Arteries (PLAC-I) trial.

Journal: The American journal of cardiology 20020715

Title: Effect of pravastatin on apolipoproteins B and C-III in very-low-density lipoproteins and low-density lipoproteins.

Journal: The American journal of cardiology 20020715

Title: Rho/Rho-kinase is involved in the synthesis of tissue factor in human monocytes.

Journal: Atherosclerosis 20020701

Title: Effect of pravastatin on proteinuria in patients with well-controlled hypertension.

Journal: Hypertension (Dallas, Tex. : 1979) 20020701

Title: Effects of combined treatment with pravastatin and ursodeoxycholic acid on hepatic cholesterol metabolism.

Journal: European journal of clinical investigation 20020701

Title: Are some statins more equal than others.

Journal: Diabetes, obesity & metabolism 20020701

Title: Molecular cloning and characterization of an ML-236B (compactin) biosynthetic gene cluster in Penicillium citrinum.

Journal: Molecular genetics and genomics : MGG 20020701

Title: Why stopping drugs abruptly can endanger cardiac recovery.

Journal: Heart advisor 20020701

Title: Resource management in prevention of coronary heart disease: optimising prescription of lipid-lowering drugs.

Journal: Lancet (London, England) 20020629

Title: Inhibition of Rho/Rho-kinase signaling downregulates plasminogen activator inhibitor-1 synthesis in cultured human monocytes.

Journal: Biochimica et biophysica acta 20020612

Title: Increased transforming growth factor-beta(1) circulating levels and production in human monocytes after 3-hydroxy-3-methyl-glutaryl-coenzyme a reductase inhibition with pravastatin.

Journal: Journal of the American College of Cardiology 20020605

Title: Effects of pravastatin in the elderly.

Journal: Annals of internal medicine 20020604

Title: Cholestasis associated with the use of pravastatin sodium.

Journal: The Medical journal of Australia 20020603

Title: Pravastatin sodium, an inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase, decreases serum total cholesterol in Japanese White rabbits by two different mechanisms.

Journal: Atherosclerosis 20020601

Title: A 16-week fenofibrate treatment increases LDL particle size in type IIA dyslipidemic patients.

Journal: Atherosclerosis 20020601

Title: A randomized, double-blind trial comparing the efficacy and safety of pitavastatin versus pravastatin in patients with primary hypercholesterolemia.

Journal: Atherosclerosis 20020601

Title: Apolipoprotein A-I deficiency with accumulated risk for CHD but no symptoms of CHD.

Journal: Atherosclerosis 20020601

Title: Extremely high dose pravastatin may suppress amyloidogenesis in a mouse model.

Journal: Annals of the rheumatic diseases 20020601

Title: Isotopomer spectral analysis of intermediates of cholesterol synthesis in human subjects and hepatic cells.

Journal: American journal of physiology. Endocrinology and metabolism 20020601

Title: Effect of apoE genotype on the hypolipidaemic response to pravastatin in an outpatient setting.

Journal: Journal of internal medicine 20020601

Title: A randomized crossover trial of combination pharmacologic therapy in children with familial hyperlipidemia.

Journal: Pediatric research 20020601

Title: Implementation of a therapeutic-interchange clinic for HMG-CoA reductase inhibitors.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20020601

Title: Pravastatin treatment-associated reduction in plasma homocysteine in heart-transplanted patients.

Journal: Transplantation proceedings 20020601

Title: The history of antibiotics: the Japanese story.

Journal: Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 20020601

Title: Mevastatin induces degeneration and decreases viability of cAMP-induced differentiated neuroblastoma cells in culture by inhibiting proteasome activity, and mevalonic acid lactone prevents these effects.

Journal: Journal of neuroscience research 20020601

Title: Policosanol: a new treatment for cardiovascular disease?

Journal: Alternative medicine review : a journal of clinical therapeutic 20020601

Title: Statin therapy: rationale for a new agent, rosuvastatin.

Journal: International journal of clinical practice 20020601

Title: Gateways to Clinical Trials. June 2002.

Journal: Methods and findings in experimental and clinical pharmacology 20020601

Title: Safety and tolerability of pravastatin in long-term clinical trials: prospective Pravastatin Pooling (PPP) Project.

Journal: Circulation 20020521

Title: Cost-effectiveness of intensive glycemic control, intensified hypertension control, and serum cholesterol level reduction for type 2 diabetes.

Journal: JAMA 20020515

Title: Effects of streptozotocin-induced diabetes on acetoacetyl-CoA synthetase activity in rats.

Journal: Biochemical pharmacology 20020515

Title: Importance of NAD(P)H oxidase-mediated oxidative stress and contractile type smooth muscle myosin heavy chain SM2 at the early stage of atherosclerosis.

Journal: Circulation 20020514

Title: Statins and risk of polyneuropathy: a case-control study.

Journal: Neurology 20020514

Title: Statin use, hyperlipidaemia, and the risk of breast cancer.

Journal: British journal of cancer 20020506

Title: A comparison of pravastatin and gemfibrozil in the treatment of dyslipoproteinemia in patients with non-insulin-dependent diabetes mellitus.

Journal: Atherosclerosis 20020501

Title: Statin use and the risk of breast and prostate cancer.

Journal: Epidemiology (Cambridge, Mass.) 20020501

Title: Atorvastatin inhibition of cytokine-inducible nitric oxide synthase expression in native endothelial cells in situ.

Journal: British journal of pharmacology 20020501

Title: Lipid-lowering drug use and cardiovascular events after myocardial infarction.

Journal: The Annals of pharmacotherapy 20020501

Title: [Results of clinical epidemiology and intervention trial of hyperlipidemia in Japan].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20020501

Title: Immunosuppressive effects of statins.

Journal: Atherosclerosis. Supplements 20020501

Title: Pharmacological interactions of statins.

Journal: Atherosclerosis. Supplements 20020501

Title: The choice of hormone replacement therapy or statin therapy in the treatment of hyperlipidemic postmenopausal women.

Journal: Atherosclerosis. Supplements 20020501

Title: Issues concerning the monitoring of statin therapy in hypercholesterolemic subjects with high plasma lipoprotein(a) levels.

Journal: Lipids 20020501

Title: Gateways to clinical trials.

Journal: Methods and findings in experimental and clinical pharmacology 20020501

Title: Statins as immunomodulators.

Journal: Transplant immunology 20020501

Title: Comparison of the efficacy and safety of pravastatin and simvastatin in heart transplantation.

Journal: The Journal of the Association of Physicians of India 20020501

Title: Risk-benefit of HMG-CoA reductase inhibitors in the treatment of HIV protease inhibitor-related hyperlipidaemia.

Journal: Expert opinion on drug safety 20020501

Title: Long-term effectiveness and safety of pravastatin in 9014 patients with coronary heart disease and average cholesterol concentrations: the LIPID trial follow-up.

Journal: Lancet (London, England) 20020420

Title: Interaction between ritonavir and statins.

Journal: The American journal of medicine 20020415

Title: Statins inhibit A beta-neurotoxicity in vitro and A beta-induced vasoconstriction and inflammation in rat aortae.

Journal: Atherosclerosis 20020401

Title: The effects of hydroxy-methyl-glutaryl co-enzyme A reductase inhibitors on platelet thrombus formation.

Journal: Atherosclerosis 20020401

Title: CD43 polarization in unprimed T cells can be dissociated from raft coalescence by inhibition of HMG CoA reductase.

Journal: Blood 20020401

Title: Comparison of low-density lipoprotein cholesterol lowering by pravastatin to <100 mg/dl versus >100 mg/dl on brachial artery vasoreactivity in patients with severe hypercholesterolemia and previous atherosclerotic events or diabetes mellitus.

Journal: The American journal of cardiology 20020401

Title: Design of the Pravastatin or Atorvastatin Evaluation and Infection Therapy (PROVE IT)-TIMI 22 trial.

Journal: The American journal of cardiology 20020401

Title: Influence of simvastatin, pravastatin, and BM 15.766 on neutral sterols in liver and testis of guinea pigs.

Journal: Metabolism: clinical and experimental 20020401

Title: Effects of hypocholesterolaemic agents on the expression and activity of 3-hydroxy-3-methylglutaryl-CoA reductase in the fat body of the German cockroach.

Journal: Archives of insect biochemistry and physiology 20020401

Title: Interleukin-6 -174G>C polymorphism and risk of coronary heart disease in West of Scotland coronary prevention study (WOSCOPS).

Journal: Arteriosclerosis, thrombosis, and vascular biology 20020401

Title: Drug-induced liver damage -- a three-year study of patients from one gastroenterological department.

Journal: Medical science monitor : international medical journal of experimental and clinical research 20020401

Title: Biosynthesis and biotechnological production of statins by filamentous fungi and application of these cholesterol-lowering drugs.

Journal: Applied microbiology and biotechnology 20020401

Title: A new reality: achieving cholesterol-lowering goals in clinical practice.

Journal: Atherosclerosis. Supplements 20020401

Title: The lower the better? Reviewing the evidence for more aggressive cholesterol reduction and goal attainment.

Journal: Atherosclerosis. Supplements 20020401

Title: Effect of vitamins C and E on progression of transplant-associated arteriosclerosis: a randomised trial.

Journal: Lancet (London, England) 20020330

Title: Coronary heart disease in patients with low LDL-cholesterol: benefit of pravastatin in diabetics and enhanced role for HDL-cholesterol and triglycerides as risk factors.

Journal: Circulation 20020326

Title: Withdrawal of statins increases event rates in patients with acute coronary syndromes.

Journal: Circulation 20020326

Title: Relationship between lipid levels and clinical outcomes in the Long-term Intervention with Pravastatin in Ischemic Disease (LIPID) Trial: to what extent is the reduction in coronary events with pravastatin explained by on-study lipid levels?

Journal: Circulation 20020312

Title: Pharmacokinetic interactions between protease inhibitors and statins in HIV seronegative volunteers: ACTG Study A5047.

Journal: AIDS (London, England) 20020308

Title: Managing dyslipidemia in the high-risk patient.

Journal: The American journal of cardiology 20020307

Title: [Myotoxicity and rhabdomyolisis due to statins].

Journal: Nederlands tijdschrift voor geneeskunde 20020302

Title: 3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitors and rhabdomyolysis: considerations in the renal failure patient.

Journal: Current opinion in nephrology and hypertension 20020301

Title: Functional involvement of rat organic anion transporter 3 (rOat3; Slc22a8) in the renal uptake of organic anions.

Journal: The Journal of pharmacology and experimental therapeutics 20020301

Title: Early benefits of pravastatin to experimentally induced atherosclerosis.

Journal: Journal of cardiovascular pharmacology 20020301

Title: Beta-blockers are associated with lower C-reactive protein concentrations in patients with coronary artery disease.

Journal: The American journal of medicine 20020301

Title: Simvastatin and lovastatin, but not pravastatin, interact with MDR1.

Journal: The Journal of pharmacy and pharmacology 20020301

Title: Experimental model of escape phenomenon in hamsters and the effectiveness of YM-53601 in the model.

Journal: British journal of pharmacology 20020301

Title: Assessment of ADRs associated with lipid-lowering agents recorded in the Department of Internal Medicine, University Hospital, Jena.

Journal: International journal of clinical pharmacology and therapeutics 20020301

Title: Evaluation of myopathy risk for HMG-CoA reductase inhibitors by urethane infusion method.

Journal: Biological & pharmaceutical bulletin 20020301

Title: Effects of an HMG-CoA reductase inhibitor in combination with an ACE inhibitor or angiotensin II type 1 receptor antagonist on myocardial metabolism in ischemic rabbit hearts.

Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20020301

Title: HMG-CoA reductase inhibitors reduce interleukin-6 synthesis in human vascular smooth muscle cells.

Journal: Cardiovascular drugs and therapy 20020301

Title: Rosuvastatin: a highly efficacious statin for the treatment of dyslipidaemia.

Journal: Expert opinion on investigational drugs 20020301

Title: Transcellular transport of organic anions across a double-transfected Madin-Darby canine kidney II cell monolayer expressing both human organic anion-transporting polypeptide (OATP2/SLC21A6) and Multidrug resistance-associated protein 2 (MRP2/ABCC2).

Journal: The Journal of biological chemistry 20020222

Title: Effects of probucol and pravastatin on common carotid atherosclerosis in patients with asymptomatic hypercholesterolemia. Fukuoka Atherosclerosis Trial (FAST).

Journal: Journal of the American College of Cardiology 20020220

Title: Statins as novel therapies for osteoporosis?

Journal: European journal of obstetrics, gynecology, and reproductive biology 20020210

Title: Expedient, stereocontrolled synthesis of (+)-compactin lactone via intramolecular Reformatsky reaction.

Journal: The Journal of organic chemistry 20020208

Title: Fluvastatin enhances apoptosis in cytokine-stimulated vascular smooth muscle cells.

Journal: Journal of cardiovascular pharmacology 20020201

Title: Statins and mortality.

Journal: European heart journal 20020201

Title: Effects of pravastatin on mortality in patients with and without coronary heart disease across a broad range of cholesterol levels. The Prospective Pravastatin Pooling project.

Journal: European heart journal 20020201

Title: Caveolae and cholesterol distribution in vascular smooth muscle cells of different phenotypes.

Journal: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 20020201

Title: Do lipid-lowering drugs cause erectile dysfunction? A systematic review.

Journal: Family practice 20020201

Title: Pharmacokinetic and pharmacodynamic assessments of HMG-CoA reductase inhibitors when coadministered with everolimus.

Journal: Journal of clinical pharmacology 20020201

Title: Safety and efficacy of atorvastatin in heart transplant recipients.

Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20020201

Title: Policosanol: clinical pharmacology and therapeutic significance of a new lipid-lowering agent.

Journal: American heart journal 20020201

Title: Leptin concentrations in GH deficiency: the effect of GH insensitivity.

Journal: The Journal of clinical endocrinology and metabolism 20020201

Title: Modulation of inflammatory mediators and PPARgamma and NFkappaB expression by pravastatin in response to lipoproteins in human monocytes in vitro.

Journal: Pharmacological research 20020201

Title: FDA adverse event reports on statin-associated rhabdomyolysis.

Journal: The Annals of pharmacotherapy 20020201

Title: Lipid-lowering therapy with fluvastatin inhibits oxidative modification of low density lipoprotein and improves vascular endothelial function in hypercholesterolemic patients.

Journal: Atherosclerosis 20020201

Title: The subcellular localization of an unusual rice calmodulin isoform, OsCaM61, depends on its prenylation status.

Journal: Plant molecular biology 20020201

Title: Effect of fluvastatin and pravastatin, HMG-CoA reductase inhibitors, on fluconazole activity against Candida albicans.

Journal: Journal of medical microbiology 20020201

Title: Detection of coronary microvascular disease by means of cardiac scintigraphy.

Journal: The Canadian journal of cardiology 20020201

Title: [Unexpected drug-interaction].

Journal: Rinsho byori. The Japanese journal of clinical pathology 20020201

Title: Effect of pravastatin treatment on the evolution of extracoronary atherosclerosis in renal transplant patients.

Journal: Transplantation proceedings 20020201

Title: Pravastatin improves low-density lipoprotein oxidation in renal transplantation.

Journal: Transplantation proceedings 20020201

Title: Angiographic intervention trial using HMG CoA reductase inhibitor to evaluate retardation of obstructive multiple atheroma in West Japan (ATHEROMA study): rationale, design and baseline.

Journal: Journal of cardiovascular risk 20020201

Title: Atorvastatin versus four statin-fibrate combinations in patients with familial combined hyperlipidaemia.

Journal: Journal of cardiovascular risk 20020201

Title: Distinct mechanisms of bisphosphonate action between osteoblasts and breast cancer cells: identity of a potent new bisphosphonate analogue.

Journal: Breast cancer research and treatment 20020201

Title: Role of transporters in the tissue-selective distribution and elimination of drugs: transporters in the liver, small intestine, brain and kidney.

Journal: Journal of controlled release : official journal of the Controlled Release Society 20020117

Title: Prevention of primary nonfunction of canine islet autografts by treatment with pravastatin.

Journal: Transplantation 20020115

Title: Hypercholesterolaemia and lipid lowering treatment do not affect the acute endogenous fibrinolytic capacity in vivo.

Journal: Heart (British Cardiac Society) 20020101

Title: Fluorescein uptake by a monocarboxylic acid transporter in human intestinal Caco-2 cells.

Journal: Biochemical pharmacology 20020101

Title: Effects of pravastatin treatment on lipoprotein subclass profiles and particle size in the PLAC-I trial.

Journal: Atherosclerosis 20020101

Title: Pravastatin suppress superoxide and fibronectin production of glomerular mesangial cells induced by oxidized-LDL and high glucose.

Journal: Atherosclerosis 20020101

Title: A pharmacoepidemiological assessment of the effect of statins and fibrates on fibrinogen concentration.

Journal: Atherosclerosis 20020101

Title: Effect of pravastatin on responsiveness to N-monomethyl-L-arginine in patients with hypercholesterolaemia.

Journal: Atherosclerosis 20020101

Title: Remarkably high prevalence of small dense low-density lipoprotein in Japanese men with coronary artery disease, irrespective of the presence of diabetes.

Journal: Atherosclerosis 20020101

Title: Rosuvastatin: a highly efficacious statin for the treatment of dyslipidaemia.

Journal: Expert opinion on investigational drugs 20020101

Title: Rhabdomyolysis and statin therapy: relevance to the elderly.

Journal: The American journal of geriatric cardiology 20020101

Title: HMG CoA reductase inhibitors affect the fibrinolytic system of human vascular cells in vitro: a comparative study using different statins.

Journal: British journal of pharmacology 20020101

Title: Maintenance of low-density lipoprotein goal with step-down pravastatin therapy.

Journal: Pharmacotherapy 20020101

Title: Cholesterol-dependent modulation of dendrite outgrowth and microtubule stability in cultured neurons.

Journal: Journal of neurochemistry 20020101

Title: Poststroke emotional incontinence and decreased sexual activity.

Journal: Cerebrovascular diseases (Basel, Switzerland) 20020101

Title: Cholesterol, essential fatty acids, and suicide.

Journal: Pharmacopsychiatry 20020101

Title: Influence of high cholesterol diet and pravastatin sodium on the initiation of liver regeneration in rats after partial hepatectomy.

Journal: Nutrition (Burbank, Los Angeles County, Calif.) 20020101

Title: Effect of early telephone and postal reminders on medication compliance with pravastatin therapy.

Journal: Clinical therapeutics 20020101

Title: Effects of pravastatin on superoxide and fibronectin production of mesangial cells induced by low-density lipoprotein.

Journal: Kidney & blood pressure research 20020101

Title: Inhibition of platelet aggregation and expression of alpha granule membrane protein 140 and thromboxane B2 with pravastatin therapy for hypercholesterolemia.

Journal: Journal of the Association for Academic Minority Physicians : the official publication of the Association for Academic Minority Physicians 20020101

Title: Statins, platelet aggregation and coronary heart disease.

Journal: Journal of the Association for Academic Minority Physicians : the official publication of the Association for Academic Minority Physicians 20020101

Title: Requirement of Rho-family GTPases in the invasion of Type 1-piliated uropathogenic Escherichia coli.

Journal: Cellular microbiology 20020101

Title: Effect of simvastatin on bone markers in osteopenic women: a placebo-controlled, dose-ranging trial [ISRCTN85429598].

Journal: BMC musculoskeletal disorders 20020101

Title: The case for early statin therapy in acute coronary syndromes.

Journal: Cardiology in review 20020101

Title: Gateways to clinical trials.

Journal: Methods and findings in experimental and clinical pharmacology 20020101

Title: Effects of pravastatin on exercise electrocardiography test performance and cardiovascular mortality and morbidity in patients with hypercholesterolemia: Lipid Intervention Study in Kyoto.

Journal: Circulation journal : official journal of the Japanese Circulation Society 20020101

Title: Statins as modulators of bone formation.

Journal: Arthritis research 20020101

Title: Pharmacokinetic-pharmacodynamic drug interactions with HMG-CoA reductase inhibitors.

Journal: Clinical pharmacokinetics 20020101

Title: The role of statins as potential targets for bone formation.

Journal: Arthritis research 20020101

Title: Statin specific toxicity in organ transplant recipients: case report and review of the literature.

Journal: Journal of nephrology 20020101

Title: Interventions in the management of serum lipids for preventing stroke recurrence.

Journal: The Cochrane database of systematic reviews 20020101

Title: A 'bad responder' to statins.

Journal: Cardiology 20020101

Title: The effects of combination therapy with niceritrol and pravastatin on hyperlipidaemia.

Journal: The Journal of international medical research 20020101

Title: Micronised fenofibrate: an updated review of its clinical efficacy in the management of dyslipidaemia.

Journal: Drugs 20020101

Title: Gateways to clinical trials.

Journal: Methods and findings in experimental and clinical pharmacology 20020101

Title: Prognosis of hypercholesterolemic patients taking pravastatin for five years: the Chiba Lipid Intervention Program (CLIP) Study.

Journal: Journal of atherosclerosis and thrombosis 20020101

Title: [Hypothyroidism, pravastatin therapy and myopathy].

Journal: Duodecim; laaketieteellinen aikakauskirja 20020101

Title: Oxysterol-induced apoptosis of vascular smooth muscle cells is reduced by HMG-CoA reductase inhibitor, pravastatin.

Journal: Journal of atherosclerosis and thrombosis 20020101

Title: Oxidation injury in patients receiving HMG-CoA reductase inhibitors: occurrence in patients without enzyme elevation or myopathy.

Journal: Drug safety 20020101

Title: Rosuvastatin.

Journal: Drugs 20020101

Title: [Concentration on Diapak C 16 capsules of lovastatin, mevinolinic acid and other inhibitors of biosynthesis of sterins produced by Penicillium citrinum 89].

Journal: Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20020101

Title: Health-related quality of life and long-term therapy with pravastatin and tocopherol (vitamin E) in older adults.

Journal: Drugs & aging 20020101

Title: Mevastatin, an inhibitor of HMG-CoA reductase, induces apoptosis, differentiation and Rap1 expression in HL-60 cells.

Journal: Physiological chemistry and physics and medical NMR 20020101

Title: Interactions between antiretroviral drugs and drugs used for the therapy of the metabolic complications encountered during HIV infection.

Journal: Clinical pharmacokinetics 20020101

Title: Effect of pravastatin-induced LDL-cholesterol reduction on coronary heart disease and cerebrovascular disease in Japanese: Hokuriku lipid coronary heart disease study-pravastatin atherosclerosis trial (Holicos-PAT).

Journal: Journal of atherosclerosis and thrombosis 20020101

Title: Colchicine-induced acute myopathy in a patient with concomitant use of simvastatin.

Journal: Clinical neuropharmacology 20020101

Title: Benefits and menaces related to the use of statins in patients after renal transplantation.

Journal: Annals of transplantation 20020101

Title: Role of inflammation in cardiovascular disease: how to use C-reactive protein in clinical practice.

Journal: Progress in cardiovascular nursing 20020101

Title: Statins and menopause.

Journal: Drugs 20020101

Title: A multidisciplinary program for achieving lipid goals in chronic hemodialysis patients.

Journal: BMC nephrology 20020101

Title: The anatomy of a clinical trial. The West of Scotland Coronary Prevention Study.

Journal: Medical principles and practice : international journal of the Kuwait University, Health Science Centre 20020101

Title: [Pravastatin: pharmacological action, pleiotropic effects and efficacy in prevention of atherosclerosis].

Journal: Kardiologiia 20020101

Title: [Correction of atherogenic exogenously-induced postprandial hyperlipidemia with pravastatin].

Journal: Kardiologiia 20020101

Title: The discovery and development of atorvastatin, a potent novel hypolipidemic agent.

Journal: Progress in medicinal chemistry 20020101

Title: The in vitro inhibitory effects of crude extracts of traditional Chinese herbs on 3-hydroxy-3-methylglutaryl-coenzyme A reductase on Vero cells.

Journal: The American journal of Chinese medicine 20020101

Title: Differential effect of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors on plasma paraoxonase 1 activity in the rat.

Journal: Polish journal of pharmacology 20020101

Title: The eye lens evaluation of the atorvastatin-treated white rat.

Journal: Annales Universitatis Mariae Curie-Sklodowska. Sectio D: Medicina 20020101

Title: Strategies for minimizing hyperlipidemia after cardiac transplantation.

Journal: American journal of cardiovascular drugs : drugs, devices, and other interventions 20020101

Title: Management of protease inhibitor-associated hyperlipidemia.

Journal: American journal of cardiovascular drugs : drugs, devices, and other interventions 20020101

Title: How do HMG-CoA reductase inhibitors prevent stroke?

Journal: American journal of cardiovascular drugs : drugs, devices, and other interventions 20020101

Title: Integrating cost-effectiveness evidence into clinical practice guidelines in Australia for acute myocardial infarction.

Journal: The European journal of health economics : HEPAC : health economics in prevention and care 20020101

Title: Modulation of COX-2 expression by statins in human aortic smooth muscle cells. Involvement of geranylgeranylated proteins.

Journal: The Journal of biological chemistry 20011214

Title: Estrogen/progesterone replacement versus pravastatin and their sequential association in hypercholesterolemic postmenopausal women.

Journal: Maturitas 20011214

Title: Diverse effects of inhibition of 3-hydroxy-3-methylglutaryl-CoA reductase on the expression of VCAM-1 and E-selectin in endothelial cells.

Journal: The Biochemical journal 20011201

Title: Effect of pravastatin on endothelial function in patients with coronary artery disease (cholesterol-independent effect of pravastatin).

Journal: The American journal of cardiology 20011201

Title: Participant recruitment in the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT).

Journal: Controlled clinical trials 20011201

Title: The effects of lipid-lowering and antioxidant vitamin therapies on flow-mediated vasodilation of the brachial artery in older adults with hypercholesterolemia.

Journal: Journal of the American College of Cardiology 20011201

Title: Pravastatin improves cerebral vasomotor reactivity in patients with subcortical small-vessel disease.

Journal: Stroke 20011201

Title: Downregulation of angiotensin II type 1 receptor by hydrophobic 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors in vascular smooth muscle cells.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20011201

Title: Effect of statin therapy on remnant lipoprotein cholesterol levels in patients with combined hyperlipidemia.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20011201

Title: Different effects of St John's wort on the pharmacokinetics of simvastatin and pravastatin.

Journal: Clinical pharmacology and therapeutics 20011201

Title: Can the potential benefits of statins in general medical practice be extrapolated to liver transplantation?

Journal: Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20011201

Title: Alpha tocopheryl succinate, retinoic acid and polar carotenoids enhanced the growth-inhibitory effect of a cholesterol-lowering drug on immortalized and transformed nerve cells in culture.

Journal: Journal of the American College of Nutrition 20011201

Title: Cost-effectiveness analysis of applying the Cholesterol and Recurrent Events (CARE) study protocol in Hong Kong.

Journal: Hong Kong medical journal = Xianggang yi xue za zhi 20011201

Title: [Lipid-lowering drugs].

Journal: Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20011201

Title: A comparison of continuous combined hormone replacement therapy, HMG-CoA reductase inhibitor and combined treatment for the management of hypercholesterolemia in postmenopausal women.

Journal: The journal of obstetrics and gynaecology research 20011201

Title: Stability of atheromatous plaque affected by lesional composition: study of WHHL rabbits treated with statins.

Journal: Annals of the New York Academy of Sciences 20011201

Title: The use of fibrates and of statins in preventing atherosclerosis in diabetes.

Journal: Current opinion in lipidology 20011201

Title: Antioxidative effects of fluvastatin and its metabolites against oxidative DNA damage in mammalian cultured cells.

Journal: Free radical research 20011201

Title: Fluvastatin depresses the enhanced lipid peroxidation in vitamin E-deficient hamsters.

Journal: Free radical research 20011201

Title: Rosuvastatin demonstrates greater reduction of low-density lipoprotein cholesterol compared with pravastatin and simvastatin in hypercholesterolaemic patients: a randomized, double-blind study.

Journal: Journal of cardiovascular risk 20011201

Title: Effect of diet and treatment with statins on platelet-dependent thrombin generation in hypercholesterolemic subjects.

Journal: Nutrition, metabolism, and cardiovascular diseases : NMCD 20011201

Title: Low-density-lipoprotein cholesterol goals for patients with coronary disease: treating between the lines.

Journal: Circulation 20011127

Title: High-sensitivity C-reactive protein: potential adjunct for global risk assessment in the primary prevention of cardiovascular disease.

Journal: Circulation 20011127

Title: Effect of pravastatin on myocardial protection during coronary angioplasty and the role of adenosine.

Journal: The American journal of cardiology 20011115

Title: Cholesterol lowering with statins reduces exercise-induced myocardial ischemia in hypercholesterolemic patients with coronary artery disease.

Journal: The American journal of cardiology 20011115

Title: Do statins reduce the risk for diabetes by improving exercise capacity?

Journal: Circulation 20011113

Title: CNS synaptogenesis promoted by glia-derived cholesterol.

Journal: Science (New York, N.Y.) 20011109

Title: Locking a leukocyte integrin with statins.

Journal: The New England journal of medicine 20011108

Title: Cost-effectiveness of prescribing statins according to pharmaceutical benefits scheme criteria.

Journal: The Medical journal of Australia 20011105

Title: Use of a reporter gene assay to predict and rank the potency and efficacy of CYP3A4 inducers.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20011101

Title: Pravastatin and endothelium dependent vasomotion after coronary angioplasty: the PREFACE trial.

Journal: Heart (British Cardiac Society) 20011101

Title: Pravastatin, a 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor, attenuates renal injury in an experimental model of ischemia-reperfusion.

Journal: The Journal of surgical research 20011101

Title: HMG-CoA reductase inhibitors reduce vascular monocyte chemotactic protein-1 expression in early lesions from hypercholesterolemic swine independently of their effect on plasma cholesterol levels.

Journal: Atherosclerosis 20011101

Title: In patients with heart disease, is the benefit of lipid-lowering therapy with statins similar in older patients to that in younger patients?

Journal: The Journal of family practice 20011101

Title: Development of indicators for assessing the quality of prescribing of lipid-lowering drugs: data from the pharmacotherapeutic quality circles in Hesse, Germany.

Journal: International journal of clinical pharmacology and therapeutics 20011101

Title: Lovastatin increases nitric oxide synthesis in IL-1 beta-stimulated smooth muscle cells.

Journal: Chinese medical journal 20011101

Title: The use over time of statins in coronary patients in an Italian tertiary referral center.

Journal: Italian heart journal : official journal of the Italian Federation of Cardiology 20011101

Title: Healthy ageing: addressing acute coronary syndrome?

Journal: European heart journal 20011101

Title: Effect of hydroxymethylglutaryl coenzyme a reductase inhibitors on the progression of calcific aortic stenosis.

Journal: Circulation 20011030

Title: Potency of select statin drugs in a new mouse model of hyperlipidemia and atherosclerosis.

Journal: International journal of pharmaceutics 20011023

Title: Alzheimer's disease. Bad for the heart, bad for the mind?

Journal: Science (New York, N.Y.) 20011019

Title: [Can the action of statins reveal etiology of coronary diseases?].

Journal: Lakartidningen 20011017

Title: beta-Oxidation of simvastatin in mouse liver preparations.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20011001

Title: Hyperlipidaemia and cardiovascular disease.

Journal: Current opinion in lipidology 20011001

Title: Effects of low-dose pravastatin on plasma levels of lipids and apolipoproteins in Japanese type II hyperlipoproteinemic subjects with apolipoprotein E phenotype E3/2, E3/3, and E4/3.

Journal: Journal of clinical pharmacology 20011001

Title: Clinically relevant differences between the statins: implications for therapeutic selection.

Journal: The American journal of medicine 20011001

Title: The synergistic hypocholesterolemic activity of the potent cholesterol absorption inhibitor, ezetimibe, in combination with 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitors in dogs.

Journal: Metabolism: clinical and experimental 20011001

Title: Effect of lipid-lowering therapy with pravastatin on myocardial blood flow in young mildly hypercholesterolemic adults.

Journal: Journal of cardiovascular pharmacology 20011001

Title: Effect of statins on bone mineral density and bone histomorphometry in rodents.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20011001

Title: [Cholesterol, omega-3 fatty acids, and suicide risk: empirical evidence and pathophysiological hypotheses].

Journal: Fortschritte der Neurologie-Psychiatrie 20011001

Title: Pravastatin suppresses the interleukin-8 production induced by thrombin in human aortic endothelial cells cultured with high glucose by inhibiting the p44/42 mitogen activated protein kinase.

Journal: British journal of pharmacology 20011001

Title: Paraoxonase genotype modifies the effect of pravastatin on high-density lipoprotein cholesterol.

Journal: Pharmacogenetics 20011001

Title: Simvastatin and atorvastatin enhance hypotensive effect of diltiazem in rats.

Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20011001

Title: Effects of pravastatin therapy on serum lipids and coronary reactivity are not associated with SREBP cleavage-activating protein polymorphism in healthy young men.

Journal: Clinical genetics 20011001

Title: Managed care trends in statin usage.

Journal: Managed care (Langhorne, Pa.) 20011001

Title: [Effect of hypolipemic agents on levels of total plasma homocysteine].

Journal: Vnitrni lekarstvi 20011001

Title: Fluvastatin in combination with rad significantly reduces graft vascular disease in rat cardiac allografts.

Journal: Transplantation 20010927

Title: Low-density lipoprotein size, pravastatin treatment, and coronary events.

Journal: JAMA 20010926

Title: Effect of pravastatin-to-simvastatin conversion on low-density-lipoprotein cholesterol.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20010915

Title: [Hypersensitivity pneumonitis in a patient taking pravastatin].

Journal: Revue des maladies respiratoires 20010901

Title: Serum leptin levels in wild and captive populations of baboons (papio): implications for the ancestral role of leptin.

Journal: The Journal of clinical endocrinology and metabolism 20010901

Title: Effects of lovastatin and pravastatin on cognitive function in military aircrew.

Journal: Aviation, space, and environmental medicine 20010901

Title: Improvement of endothelial function in insulin-resistant carotid arteries treated with pravastatin.

Journal: Journal of neurosurgery 20010901

Title: Smoking diminishes the beneficial effect of statins: observations from the landmark trials.

Journal: Angiology 20010901

Title: [Cholesterin synthase inhibition and atherosclerosis].

Journal: Der Internist 20010901

Title: Rhabdomyolysis and HMG-CoA reductase inhibitors.

Journal: The Annals of pharmacotherapy 20010901

Title: Cerivastatin versus branded pravastatin in the treatment of primary hypercholesterolemia in primary care practice in Canada: a one-year, open-label, randomized, comparative study of efficacy, safety, and cost-effectiveness.

Journal: Clinical therapeutics 20010901

Title: Statins in acute coronary syndromes: from bench to bedside.

Journal: International journal of clinical practice 20010901

Title: Long-term efficacy and safety of cerivastatin 0.8 mg in patients with primary hypercholesterolemia.

Journal: Clinical cardiology 20010901

Title: Role of cardiac ATP-sensitive K+ channels induced by HMG CoA reductase inhibitor in ischemic rabbit hearts.

Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20010901

Title: Lipophilic statins can be osteogenic by promoting osteoblastic calcification in a Cbfa1- and BMP-2-independent manner.

Journal: Methods and findings in experimental and clinical pharmacology 20010901

Title: Statins in the 21st century: end of the simple story?

Journal: Expert opinion on investigational drugs 20010901

Title: Antiinflammatory and antiarteriosclerotic actions of HMG-CoA reductase inhibitors in a rat model of chronic inhibition of nitric oxide synthesis.

Journal: Circulation research 20010831

Title: Dietary advice with or without pravastatin for the management of hypercholesterolaemia associated with protease inhibitor therapy.

Journal: AIDS (London, England) 20010817

Title: Are we aggressive enough in lowering cholesterol?

Journal: The American journal of cardiology 20010816

Title: Achieving and maintaining National Cholesterol Education Program low-density lipoprotein cholesterol goals with five statins.

Journal: The American journal of medicine 20010815

Title: The platelet Pl(A2) and angiotensin-converting enzyme (ACE) D allele polymorphisms and the risk of recurrent events after acute myocardial infarction.

Journal: The American journal of cardiology 20010815

Title: Inhibitory effects of fluvastain and its metabolites on the formation of several reactive oxygen species.

Journal: Life sciences 20010810

Title: Correlation of non-high-density lipoprotein cholesterol with apolipoprotein B: effect of 5 hydroxymethylglutaryl coenzyme A reductase inhibitors on non-high-density lipoprotein cholesterol levels.

Journal: The American journal of cardiology 20010801

Title: Reduced levels of TNF alpha in hypercholesterolemic individuals after treatment with pravastatin for 8 weeks.

Journal: Atherosclerosis 20010801

Title: Combined treatment with low-dose pravastatin and fish oil in post-renal transplantation dislipidemia.

Journal: Nephron 20010801

Title: The effect of pravastatin and atorvastatin on coenzyme Q10.

Journal: American heart journal 20010801

Title: Foundations for blockbuster drugs in federally sponsored research.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20010801

Title: Rho-dependent inhibition of the induction of connective tissue growth factor (CTGF) by HMG CoA reductase inhibitors (statins).

Journal: British journal of pharmacology 20010801

Title: Possible relationship between statin use and decreased incidence of dementia: are we ready for a new indication for these drugs?

Journal: Archives of internal medicine 20010801

Title: A new statin: a new standard.

Journal: Clinical cardiology 20010801

Title: Shoulder stiffness: a common adverse effect of HMG-CoA reductase inhibitors in women?

Journal: Internal medicine (Tokyo, Japan) 20010801

Title: Possible active transport mechanism in pharmacokinetics of flunixin-meglumin in rabbits.

Journal: The Journal of veterinary medical science 20010801

Title: Metabolism and drug interactions of 3-hydroxy-3-methylglutaryl coenzyme A-reductase inhibitors (statins).

Journal: European journal of clinical pharmacology 20010801

Title: Effect of pravastatin in mildly hypercholesterolemic young men on serum matrix metalloproteinases.

Journal: The American journal of cardiology 20010715

Title: Effect of cholesterol-lowering therapy on endothelial function.

Journal: Circulation 20010710

Title: Effect of statin therapy on C-reactive protein levels: the pravastatin inflammation/CRP evaluation (PRINCE): a randomized trial and cohort study.

Journal: JAMA 20010704

Title: Placing PRINCE in perspective.

Journal: JAMA 20010704

Title: HMG-CoA reductase inhibitor mevastatin enhances the growth inhibitory effect of butyrate in the colorectal carcinoma cell line Caco-2.

Journal: Carcinogenesis 20010701

Title: Is pseudocholinesterase activity related to markers of triacylglycerol synthesis in Type II diabetes mellitus?

Journal: Clinical science (London, England : 1979) 20010701

Title: Influence of pravastatin on lipoproteins, and on endothelial, platelet, and inflammatory markers in subjects with peripheral artery disease.

Journal: The American journal of cardiology 20010701

Title: Fibromuscular cap composition is important for the stability of established atherosclerotic plaques in mature WHHL rabbits treated with statins.

Journal: Atherosclerosis 20010701

Title: Lipophilic statins augment inducible nitric oxide synthase expression in cytokine-stimulated cardiac myocytes.

Journal: Journal of cardiovascular pharmacology 20010701

Title: Statins and dementia.

Journal: Archives of neurology 20010701

Title: Long-term risk stratification for survivors of acute coronary syndromes. Results from the Long-term Intervention with Pravastatin in Ischemic Disease (LIPID) Study. LIPID Study Investigators.

Journal: Journal of the American College of Cardiology 20010701

Title: Pravastatin reduces myocardial lesions induced by acute inhibition of nitric oxide biosynthesis in normocholesterolemic rats.

Journal: International journal of cardiology 20010701

Title: Effects of fluvastatin and its major metabolites on low-density lipoprotein oxidation and cholesterol esterification in macrophages.

Journal: Japanese journal of pharmacology 20010701

Title: Short-term effects of statin therapy in patients with hyperlipoproteinemia after liver transplantation: results of a randomized cross-over trial.

Journal: Journal of hepatology 20010701

Title: Heart lines. Can statins help prevent diabetes?

Journal: Harvard heart letter : from Harvard Medical School 20010701

Title: The role of cytochrome P450-mediated drug-drug interactions in determining the safety of statins.

Journal: Expert opinion on pharmacotherapy 20010701

Title: The in vitro inhibitory effect of flavonoid astilbin on 3-hydroxy-3-methylglutaryl coenzyme A reductase on Vero cells.

Journal: Zhonghua yi xue za zhi = Chinese medical journal; Free China ed 20010701

Title: Conversion of cyclic nonaketides to lovastatin and compactin by a lovC deficient mutant of Aspergillus terreus.

Journal: Bioorganic & medicinal chemistry letters 20010618

Title: Statins and fractures.

Journal: Lancet (London, England) 20010609

Title: Compactin enhances osteogenesis in murine embryonic stem cells.

Journal: Biochemical and biophysical research communications 20010608

Title: Limitation of heart growth in neonatal piglets by simvastatin and atorvastatin: comparison with pravastatin.

Journal: American journal of physiology. Heart and circulatory physiology 20010601

Title: Human liver-specific organic anion transporter, LST-1, mediates uptake of pravastatin by human hepatocytes.

Journal: The Journal of pharmacology and experimental therapeutics 20010601

Title: PRINCE's prospects: statins, inflammation, and coronary risk.

Journal: American heart journal 20010601

Title: The pravastatin inflammation CRP evaluation (PRINCE): rationale and design.

Journal: American heart journal 20010601

Title: Randomized clinical trials and recent patterns in the use of statins.

Journal: American heart journal 20010601

Title: Fluvastatin suppresses oxidative stress and fibrosis in the interstitium of mouse kidneys with unilateral ureteral obstruction.

Journal: Kidney international 20010601

Title: Statins selectively inhibit leukocyte function antigen-1 by binding to a novel regulatory integrin site.

Journal: Nature medicine 20010601

Title: Effect of lovastatin, an HMG CoA reductase inhibitor, on acute renal allograft rejection.

Journal: Clinical transplantation 20010601

Title: HMG-CoA reductase inhibitors prevent migration of human coronary smooth muscle cells through suppression of increase in oxidative stress.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20010601

Title: Simvastatin-associated memory loss.

Journal: Pharmacotherapy 20010601

Title: Safety and efficacy of pravastatin therapy for the prevention of hyperlipidemia in pediatric and adolescent cardiac transplant recipients.

Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20010601

Title: Statin therapy and the prevention of dementia.

Journal: Archives of neurology 20010601

Title: Pravastatin therapy increases procollagen I N-terminal propeptide (PINP), a marker of bone formation in post-menopausal women.

Journal: Clinica chimica acta; international journal of clinical chemistry 20010601

Title: Inhibition of growth of methane-producing bacteria of the ruminant forestomach by hydroxymethylglutaryl-SCoA reductase inhibitors.

Journal: Journal of dairy science 20010601

Title: The effects of postal and telephone reminders on compliance with pravastatin therapy in a national registry: results of the first myocardial infarction risk reduction program.

Journal: Clinical therapeutics 20010601

Title: [Stroke, cholesterol and statins--are there new data about stroke prevention?].

Journal: Deutsche medizinische Wochenschrift (1946) 20010601

Title: Diabetes, statins and cardiovascular disease.

Journal: International journal of clinical practice 20010601

Title: Pravastatin in acute ischaemic syndromes: results of a randomised placebo-controlled trial.

Journal: International journal of clinical practice 20010601

Title: Plasmodium falciparum: the lethal effects of tunicamycin and mevastatin on the parasite are not mediated by the inhibition of N-linked oligosaccharide biosynthesis.

Journal: Experimental parasitology 20010601

Title: HMG-CoA reductase inhibitors (statins) characterized as direct inhibitors of P-glycoprotein.

Journal: Pharmaceutical research 20010601

Title: [CSE inhibitors after coronary event. How soon administered?].

Journal: MMW Fortschritte der Medizin 20010531

Title: Chromatographic purification of some 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors.

Journal: Journal of chromatography. A 20010525

Title: Synthesis and biological evaluations of condensed pyridine and condensed pyrimidine-based HMG-CoA reductase inhibitors.

Journal: Bioorganic & medicinal chemistry letters 20010521

Title: Benefits of pravastatin on cardiovascular events and mortality in older patients with coronary heart disease are equal to or exceed those seen in younger patients: Results from the LIPID trial.

Journal: Annals of internal medicine 20010515

Title: Summaries for patients. Benefits of lowering cholesterol levels in older patients.

Journal: Annals of internal medicine 20010515

Title: [Statins as new therapeutic possibility in osteoporosis?].

Journal: Deutsche medizinische Wochenschrift (1946) 20010511

Title: Cholesterol ester accumulation: an immediate consequence of acute in vivo ischemic renal injury.

Journal: Kidney international 20010501

Title: Aggressive versus moderate lipid-lowering therapy in postmenopausal women with hypercholesterolemia: Rationale and design of the Beyond Endorsed Lipid Lowering with EBT Scanning (BELLES) trial.

Journal: American heart journal 20010501

Title: Cost-effectiveness of pravastatin therapy for survivors of myocardial infarction with average cholesterol levels.

Journal: American heart journal 20010501

Title: Effects of 1-year treatment with fluvastatin or pravastatin on bone.

Journal: The American journal of medicine 20010501

Title: Interactions of leptin and thyrotropin 24-hour secretory profiles in short normal children.

Journal: The Journal of clinical endocrinology and metabolism 20010501

Title: The in vitro inhibitory effect of tannin derivatives on 3-hydroxy-3-methylglutaryl-coenzyme a reductase on vero cells.

Journal: Pharmacology 20010501

Title: What do the statin trials tell us?

Journal: The American journal of managed care 20010501

Title: [Pravastatin and the development of diabetes mellitus. Evidence for a protective treatment effect in the West of Scotland Coronary Prevention Study].

Journal: Italian heart journal. Supplement : official journal of the Italian Federation of Cardiology 20010501

Title: Statin induced myopathy does not show up in MIBI scintigraphy.

Journal: Nuclear medicine communications 20010501

Title: Protective effects of Saiko-ka-ryukotsu-borei-to (Chai-Hu-Jia-Long-Gu-Mu-Li-Tang) against atherosclerosis in Kurosawa and Kusanagi-hypercholesterolemic (KHC) rabbits.

Journal: Pharmacological research 20010501

Title: A cost-effectiveness model of alternative statins to achieve target LDL-cholesterol levels.

Journal: International journal of clinical practice 20010501

Title: Reassuring effect of pravastatin on natural killer cell activity in stable renal transplant patients.

Journal: Transplantation 20010427

Title: New pharmacologic aspects of CS-866, the newest angiotensin II receptor antagonist.

Journal: The American journal of cardiology 20010419

Title: [Acute coronary syndrome. Early lipid reduction decreases risk of recurrence].

Journal: MMW Fortschritte der Medizin 20010419

Title: Effect of hydroxymethyl glutaryl coenzyme a reductase inhibitor therapy on high sensitive C-reactive protein levels.

Journal: Circulation 20010417

Title: Assessing the results: phase 1 hyperlipidemia outcomes in 27 health plans.

Journal: The American journal of medicine 20010416

Title: [Effect on plasma fibrinogen of hypercholesterolaemia treatment with pravastatin].

Journal: Atencion primaria 20010415

Title: Safety of statins (hydroxymethyl glutaryl coenzyme a reductase inhibitors): different mechanisms of metabolism and drug transport may have clinical relevance.

Journal: Archives of internal medicine 20010409

Title: Cell cycle-related changes in regulatory volume decrease and volume-sensitive chloride conductance in mouse fibroblasts.

Journal: Journal of cellular physiology 20010401

Title: Comparative study of HMG-CoA reductase inhibitors on fibrinogen.

Journal: Atherosclerosis 20010401

Title: Recent clinical trial highlights in hypertension.

Journal: Current hypertension reports 20010401

Title: A new simvastatin (mevinolin)-resistance marker from Haloarcula hispanica and a new Haloferax volcanii strain cured of plasmid pHV2.

Journal: Microbiology (Reading, England) 20010401

Title: Mevastatin, an HMG-CoA reductase inhibitor, reduces stroke damage and upregulates endothelial nitric oxide synthase in mice.

Journal: Stroke 20010401

Title: Effect of pravastatin on survival in patients with advanced hepatocellular carcinoma. A randomized controlled trial.

Journal: British journal of cancer 20010401

Title: Therapeutic change of HMG-CoA reductase inhibitors in patients with coronary artery disease.

Journal: Pharmacotherapy 20010401

Title: Baseline characteristics of the diabetic participants in the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT).

Journal: Diabetes care 20010401

Title: Pravastatin attenuates lower torso ischaemia-reperfusion-induced lung injury by upregulating constitutive endothelial nitric oxide synthase.

Journal: European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery 20010401

Title: [Secondary prevention of coronary artery disease with lipid-lowering drugs].

Journal: Annales de medecine interne 20010401

Title: [Does statin therapy reduce the risk of stroke? A meta-analysis].

Journal: Annales de medecine interne 20010401

Title: Statins enhance arachidonic acid synthesis in hypercholesterolemic patients.

Journal: Nutrition, metabolism, and cardiovascular diseases : NMCD 20010401

Title: The relationship between low-density lipoprotein cholesterol goal attainment and prevention of coronary heart disease--related events.

Journal: Journal of cardiovascular pharmacology and therapeutics 20010401

Title: The effect of HMG-CoA reductase inhibitors on chronic allograft rejection.

Journal: Expert opinion on emerging drugs 20010401

Title: Pravastatin and coronary heart disease.

Journal: Lancet (London, England) 20010331

Title: Dementia and statins. PROSPER study group.

Journal: Lancet (London, England) 20010317

Title: Dementia and statins.

Journal: Lancet (London, England) 20010317

Title: 3-Hydroxy-3-methylglutaryl coenzyme A synthase-1 of Blattella germanica has structural and functional features of an active retrogene.

Journal: Insect biochemistry and molecular biology 20010315

Title: Effect of pravastatin on plasma markers of inflammation and peripheral endothelial function in male heart transplant recipients.

Journal: The American journal of cardiology 20010315

Title: Statin therapy: where are we? Where do we go next?

Journal: The American journal of cardiology 20010308

Title: Preclinical and clinical pharmacology of Rosuvastatin, a new 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor.

Journal: The American journal of cardiology 20010308

Title: A comparison of the effects of 3-hydroxy-3-methylglutaryl-coenzyme a (HMG-CoA) reductase inhibitors on the CYP3A4-dependent oxidation of mexazolam in vitro.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20010301

Title: Design and rationale of the ARBITER trial (Arterial Biology for the Investigation of the Treatment Effects of Reducing Cholesterol)--a randomized trial comparing the effects of atorvastatin and pravastatin on carotid artery intima-media thickness.

Journal: American heart journal 20010301

Title: HMG-CoA reductase inhibitors and P-glycoprotein modulation.

Journal: British journal of pharmacology 20010301

Title: Inhibition of human tumor cell growth in vivo by an orally bioavailable inhibitor of human farnesyltransferase, BIM-46228.

Journal: International journal of cancer 20010301

Title: Statin therapy--what now?

Journal: Drug and therapeutics bulletin 20010301

Title: Statin-fibrate combinations in patients with combined hyperlipedemia.

Journal: Atherosclerosis 20010301

Title: Medical-economical aspects of high sensitivity C-reactive protein assay for the prediction of coronary heart disease. An analysis in Germany and Italy.

Journal: Italian heart journal : official journal of the Italian Federation of Cardiology 20010301

Title: [Treatment with statins for the reduction of cardiovascular risk].

Journal: Italian heart journal. Supplement : official journal of the Italian Federation of Cardiology 20010301

Title: [Effects of pravastatin in 3260 patients with unstable angina: results from the LIPID study].

Journal: Italian heart journal. Supplement : official journal of the Italian Federation of Cardiology 20010301

Title: Role of fibrates and HMG-CoA reductase inhibitors in gallstone formation: epidemiological study in an unselected population.

Journal: Digestive diseases and sciences 20010301

Title: Is a statin a statin?

Journal: International journal of clinical practice 20010301

Title: [WOSCOPS [West of Scotland Coronary Prevention Study]].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20010301

Title: [LIPID study [Long-term Intervention with Pravastatin in Ischaemic Disease study]].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20010301

Title: [REGRESS [The Regression Growth Evaluation Statin Study]].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20010301

Title: [CARE[ Cholesterol and Recurrent Events Trial]].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20010301

Title: [PATE Study [Pravastatin anti-Atherosclerosis Trial in the Elderly Study]].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20010301

Title: Statins: new drugs for treating osteoporosis?

Journal: Expert opinion on investigational drugs 20010301

Title: A clinical focus on statins.

Journal: Current opinion in investigational drugs (London, England : 2000) 20010301

Title: Suppression of recurrent transient ischemic attacks by a statin agent.

Journal: Neurology 20010227

Title: Pravastatin treatment increases collagen content and decreases lipid content, inflammation, metalloproteinases, and cell death in human carotid plaques: implications for plaque stabilization.

Journal: Circulation 20010220

Title: Statins alter smooth muscle cell accumulation and collagen content in established atheroma of watanabe heritable hyperlipidemic rabbits.

Journal: Circulation 20010220

Title: Effect of pravastatin on frequency of fracture in the LIPID study: secondary analysis of a randomised controlled trial. Long-term Intervention with Pravastatin in Ischaemic Disease.

Journal: Lancet (London, England) 20010217

Title: [Acute coronary syndrome. Statins in the early phase save lives].

Journal: MMW Fortschritte der Medizin 20010208

Title: Operational aspects of terminating the doxazosin arm of The Antihypertensive and Lipid Lowering Treatment to Prevent Heart Attack Trial (ALLHAT).

Journal: Controlled clinical trials 20010201

Title: Lovastatin induces apoptosis of spontaneously immortalized rat brain neuroblasts: involvement of nonsterol isoprenoid biosynthesis inhibition.

Journal: Molecular and cellular neurosciences 20010201

Title: Do HMG-CoA reductase inhibitors affect fibrinogen?

Journal: The Annals of pharmacotherapy 20010201

Title: Protective effect of fluvastatin on degradation of apolipoprotein B by a radical reaction in human plasma.

Journal: Biological & pharmaceutical bulletin 20010201

Title: [Statins: intervention studies, facts and perspectives].

Journal: Annales d'endocrinologie 20010201

Title: Antioxidative effect of fluvastatin, an inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase, on peroxidation of phospholipid liposomes.

Journal: The Journal of pharmacy and pharmacology 20010201

Title: Clinical relevance of statins: instituting treatment early in acute coronary syndrome patients.

Journal: Atherosclerosis. Supplements 20010201

Title: Clinical relevance of statins: their role in secondary prevention.

Journal: Atherosclerosis. Supplements 20010201

Title: [Determination of pravastatin in rat liver by RP-HPLC].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20010201

Title: Beneficial effects of pravastatin in peri- and postmenopausal hyperlipidemic women: a 5-year study on serum lipid and sex hormone levels.

Journal: Maturitas 20010131

Title: Interim monitoring of clinical trials based on long-term binary endpoints.

Journal: Statistics in medicine 20010130

Title: Do interventions to reduce coronary heart disease reduce the incidence of type 2 diabetes? A possible role for inflammatory factors.

Journal: Circulation 20010123

Title: Statins for stroke: the second story?

Journal: Circulation 20010123

Title: Pravastatin and the development of diabetes mellitus: evidence for a protective treatment effect in the West of Scotland Coronary Prevention Study.

Journal: Circulation 20010123

Title: Reduction of stroke events with pravastatin: the Prospective Pravastatin Pooling (PPP) Project.

Journal: Circulation 20010123

Title: Use of the statins in patients after acute myocardial infarction: does evidence change practice?

Journal: Archives of internal medicine 20010122

Title: [Metabolic interactions with statins].

Journal: Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20010120

Title: Effective use of statins to prevent coronary heart disease.

Journal: American family physician 20010115

Title: Statin trials in progress: unanswered questions.

Journal: Current atherosclerosis reports 20010101

Title: New statins and new doses of older statins.

Journal: Current atherosclerosis reports 20010101

Title: Effects of initial and long-term lipid-lowering therapy on vascular wall characteristics.

Journal: Atherosclerosis 20010101

Title: Inflammation and coronary heart disease: an overview.

Journal: Cardiology in review 20010101

Title: [Antioxidative effects of fluvastatin, and its major metabolites [II]].

Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20010101

Title: Systolic and pulse blood pressures (but not diastolic blood pressure and serum cholesterol) are associated with alterations in carotid intima-media thickness in the moderately hypercholesterolaemic hypertensive patients of the Plaque Hypertension Lipid Lowering Italian Study. PHYLLIS study group.

Journal: Journal of hypertension 20010101

Title: Similar effects of atorvastatin, simvastatin and pravastatin on thrombogenic and inflammatory parameters in patients with hypercholesterolemia.

Journal: Thrombosis and haemostasis 20010101

Title: Cholesterol-dependent modulation of tau phosphorylation in cultured neurons.

Journal: Journal of neurochemistry 20010101

Title: Hypolipidemic effect of NK-104 and other 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors in guinea pigs.

Journal: Arzneimittel-Forschung 20010101

Title: Protective effects of fluvastatin against reactive oxygen species induced DNA damage and mutagenesis.

Journal: Free radical research 20010101

Title: Advantages of lipid-lowering therapy in cerebral ischemia: role of HMG-CoA reductase inhibitors.

Journal: Cerebrovascular diseases (Basel, Switzerland) 20010101

Title: Cost effectiveness of HMG-CoA reductase inhibition in Canada.

Journal: The Canadian journal of clinical pharmacology = Journal canadien de pharmacologie clinique 20010101

Title: New OTC drugs and devices 2000: a selective review.

Journal: Journal of the American Pharmaceutical Association (Washington,D.C. : 1996) 20010101

Title: Stimulation of inflammatory responses in vitro and in vivo by lipophilic HMG-CoA reductase inhibitors.

Journal: International immunopharmacology 20010101

Title: The devil is in the details.

Journal: The American journal of geriatric cardiology 20010101

Title: Statin-stimulated nitric oxide release from endothelium.

Journal: Medical science monitor : international medical journal of experimental and clinical research 20010101

Title: Elevated baseline triglyceride levels modulate effects of HMGCoA reductase inhibitors on plasma lipoproteins.

Journal: Journal of cardiovascular pharmacology and therapeutics 20010101

Title: The use of percentage change from baseline as an outcome in a controlled trial is statistically inefficient: a simulation study.

Journal: BMC medical research methodology 20010101

Title: [Rhabdomyolysis and acute renal failure secondary to statins].

Journal: Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20010101

Title: Transplanted livers and kidneys for HIV+ people.

Journal: TreatmentUpdate 20010101

Title: Statins for the reduction of risk of Alzheimer's disease.

Journal: The Cochrane database of systematic reviews 20010101

Title: Statins for the prevention of Alzheimer's disease.

Journal: The Cochrane database of systematic reviews 20010101

Title: Atorvastatin: an updated review of its pharmacological properties and use in dyslipidaemia.

Journal: Drugs 20010101

Title: Prolongation of islet allograft survival in mice by combined treatment with pravastatin and low-dose cyclosporine.

Journal: Cell transplantation 20010101

Title: Pharmacological intervention in renal fibrosis and vascular sclerosis.

Journal: Journal of nephrology 20010101

Title: New data affirm the long-term safety of prevastatin.

Journal: Cardiovascular journal of South Africa : official journal for Southern Africa Cardiac Society [and] South African Society of Cardiac Practitioners 20010101

Title: [Microbiological research for the Hungarian pharmaceutical industry].

Journal: Acta pharmaceutica Hungarica 20010101

Title: A comparison of low versus standard dose pravastatin therapy for the prevention of cardiovascular events in the elderly: the pravastatin anti-atherosclerosis trial in the elderly (PATE).

Journal: Journal of atherosclerosis and thrombosis 20010101

Title: What does the future hold for diabetic dyslipidaemia?

Journal: Acta diabetologica 20010101

Title: Efficacy of n-3 polyunsaturated fatty acids after myocardial infarction: results of GISSI-Prevenzione trial. Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto Miocardico.

Journal: Lipids 20010101

Title: Some nutritional factors influencing mevinolin production by Aspergillus terreus strain.

Journal: Folia microbiologica 20010101

Title: Atorvastatin plus pravastatin for the treatment of heterozygous familial hypercholesterolaemia--a pilot study.

Journal: Current medical research and opinion 20010101

Title: If LDL-C is the answer...what was the question? What do the data really show?

Journal: Heart disease (Hagerstown, Md.) 20010101

Title: Lovastatin inhibits phenylephrine-induced ERK activation and growth of cardiac.

Journal: Cardiovascular toxicology 20010101

Title: Differences in the effects of HMG-CoA reductase inhibitors on proliferation and viability of smooth muscle cells in culture.

Journal: Atherosclerosis 20000601

Title: Compactin and simvastatin, but not pravastatin, induce bone morphogenetic protein-2 in human osteosarcoma cells.

Journal: Biochemical and biophysical research communications 20000519

Title: Pravastatin compared to bezafibrate in the treatment of dyslipidemia in insulin-treated patients with type 2 diabetes mellitus.

Journal: Diabetes/metabolism research and reviews 20000101

Title: ras p21 Isoprenylation inhibition induces flat colon tumors in Wistar rats.

Journal: Diseases of the colon and rectum 20000101

Title: Rhabdomyolysis and acute renal failure after changing statin-fibrate combinations.

Journal: Cardiology 20000101

Title: Acute cholestatic hepatitis associated with pravastatin.

Journal: The American journal of gastroenterology 19990501

Title: Two different types of exercise-induced muscle pain without myopathy and CK-elevation during HMG-Co-enzyme-A-reductase inhibitor treatment.

Journal: Atherosclerosis 19990401

Title: Polymyalgia, hypersensitivity pneumonitis and other reactions in patients receiving HMG-CoA reductase inhibitors: a report of ten cases.

Journal: Chest 19990301

Title: Myotonia associated with sarcoidosis: marked exacerbation with pravastatin.

Journal: Clinical neuropharmacology 19990101

Title: Porphyria cutanea tarda induced by the use of pravastatin.

Journal: Archives of dermatology 19981001

Title: [Influence of pravastatin therapy on expression of P-selectin].

Journal: Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 19980901

Title: Peripheral neuropathy and lipid-lowering therapy.

Journal: Southern medical journal 19980701

Title: Purification and characterization of two mevalonate pyrophosphate decarboxylases from rat liver: a novel molecular species of 37 kDa.

Journal: Journal of biochemistry 19970901

Title: Effects of HMG-CoA reductase inhibitors on growth and differentiation of cultured rat skeletal muscle cells.

Journal: Biochimica et biophysica acta 19960412

Title: [Reduction of cardiovascular events with pravastatin. A pooled analysis of clinical events within the scope of the Pravastatin Atherosclerosis Intervention Program].

Journal: Fortschritte der Medizin 19960320

Title: Reduction in cardiovascular events during pravastatin therapy. Pooled analysis of clinical events of the Pravastatin Atherosclerosis Intervention Program.

Journal: Circulation 19951101

Title: (Aryloxy)methylsilane derivatives as new cholesterol biosynthesis inhibitors: synthesis and hypocholesterolemic activity of a new class of squalene epoxidase inhibitors.

Journal: Journal of medicinal chemistry 19950818

Title: Pravastatin-associated myopathy. Report of a case.

Journal: Recenti progressi in medicina 19950501

Title: HMG-CoA reductase inhibitor therapy and peripheral neuropathy.

Journal: Annals of internal medicine 19940601

Title: [Porphyria cutanea tarda induced by HMG CoA reductase inhibitors: simvastatin, pravastatin].

Journal: Annales de dermatologie et de venereologie 19940101

Title: Inhibitors of cholesterol biosynthesis. 1. 3,5-Dihydroxy-7-(N-imidazolyl)-6-heptenoates and -heptanoates, a novel series of HMG-CoA reductase inhibitors.

Journal: Journal of medicinal chemistry 19931112

Title: Inhibitors of cholesterol biosynthesis. 2. 3,5-Dihydroxy-7-(N-pyrrolyl)-6-heptenoates, a novel series of HMG-CoA reductase inhibitors.

Journal: Journal of medicinal chemistry 19931112

Title: Pravastatin inhibited the cholesterol synthesis in human hepatoma cell line Hep G2 less than simvastatin and lovastatin, which is reflected in the upregulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase and squalene synthase.

Journal: Biochemical pharmacology 19930609

Title: RG 12561 (dalvastatin): a novel synthetic inhibitor of HMG-CoA reductase and cholesterol-lowering agent.

Journal: Pharmacology 19930101

Title: Depressive symptoms in hypercholesterolaemic patients treated with pravastatin.

Journal: Lancet (London, England) 19921010

Title: Synthesis and biological evaluation of dihydroeptastatin, a novel inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase.

Journal: Journal of medicinal chemistry 19920904

Title: Pravastatin-associated inflammatory myopathy.

Journal: The New England journal of medicine 19920827

Title: Myopathy associated with HMG-CoA reductase inhibitors (HMGRIs) and cyclosporin A: evaluation in a rat model.

Journal: European heart journal 19920701

Title: Inhibitors of cholesterol biosynthesis. 6. trans-6-[2-(2-N-heteroaryl-3,5-disubstituted- pyrazol-4-yl)ethyl/ethenyl]tetrahydro-4-hydroxy-2H-pyran-2-ones.

Journal: Journal of medicinal chemistry 19920529

Title: Hepatotoxicity of hydroxy-methyl-glutaryl-coenzyme A reductase inhibitors.

Journal: Minerva gastroenterologica e dietologica 19920101

Title: Lack of hypotension with lovastatin and pravastatin.

Journal: Lancet (London, England) 19911123

Title: HMG-CoA reductase inhibitor-induced myopathy in the rat: cyclosporine A interaction and mechanism studies.

Journal: The Journal of pharmacology and experimental therapeutics 19910601

Title: Purification and regulation of mevalonate kinase from rat liver.

Journal: The Journal of biological chemistry 19900205

Title: Treatment of heterozygous familial hypercholesterolemia with lipid-lowering drugs.

Journal: Arteriosclerosis (Dallas, Tex.) 19890101

Title: McTavish D, et al. Pravastatin. A review of its pharmacological properties and therapeutic potential in hypercholesterolaemia. Drugs. 1991 Jul;42(1):65-89.

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Tags:81093-37-0 Molecular Formula|81093-37-0 MDL|81093-37-0 SMILES|81093-37-0 (βR,δR,1S,2S,6S,8S,8aR)-1,2,6,7,8,8a-Hexahydro-β,δ,6-trihydroxy-2-methyl-8-[(2S)-2-methyl-1-oxobutoxy]-1-naphthaleneheptanoic acid