Home Amines 81732-46-9
81732-46-9,MFCD03427293
Catalog No.:AA003NVQ

81732-46-9 | 3-[2-(tert-butylamino)-1-hydroxyethyl]-5-[(dimethylcarbamoyl)oxy]phenyl N,N-dimethylcarbamate hydrochloride

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100mg
≥95%
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250mg
98%(HPLC)
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1g
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$112.00   $78.00
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5g
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10g
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25g
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
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Technical Information
Catalog Number:
AA003NVQ
Chemical Name:
3-[2-(tert-butylamino)-1-hydroxyethyl]-5-[(dimethylcarbamoyl)oxy]phenyl N,N-dimethylcarbamate hydrochloride
CAS Number:
81732-46-9
Molecular Formula:
C18H30ClN3O5
Molecular Weight:
403.9009
MDL Number:
MFCD03427293
SMILES:
O=C(N(C)C)Oc1cc(cc(c1)OC(=O)N(C)C)C(CNC(C)(C)C)O.Cl
NSC Number:
758916
Properties
Properties
 
BP:
500.9°C at 760 mmHg  
Form:
Solid  
MP:
222-224°C  
Solubility:
H2O: ~33 mg/mL, soluble  
Storage:
Inert atmosphere;Room Temperature;  

Computed Properties
 
Complexity:
446  
Covalently-Bonded Unit Count:
2  
Heavy Atom Count:
27  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
8  
Undefined Atom Stereocenter Count:
1  

Literature

Title: Design and mechanism of on-off pulsed drug release using nonenteric polymeric systems via pH modulation.

Journal: AAPS PharmSciTech 20110301

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: Effects of bambuterol and terbutaline on isolated rat's tracheal smooth muscle.

Journal: European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery 20100801

Title: Simultaneous analysis of bambuterol and its active metabolite terbutaline enantiomers in rat plasma by chiral liquid chromatography-tandem mass spectrometry.

Journal: Journal of pharmaceutical and biomedical analysis 20100605

Title: Influence of differential expression of acetylcholinesterase in brain and muscle on respiration.

Journal: Respiratory physiology & neurobiology 20090101

Title: Stereoselective inhibition of human, mouse, and horse cholinesterases by bambuterol enantiomers.

Journal: Chemico-biological interactions 20080925

Title: Highly enantioselective synthesis, crystal structure, and circular dichroism spectroscopy of (R)-bambuterol hydrochloride.

Journal: Chirality 20080701

Title: Amino acid residues involved in stereoselective inhibition of cholinesterases with bambuterol.

Journal: Archives of biochemistry and biophysics 20080301

Title: Simultaneous estimation of Montelukast sodium and Bambuterol hydrochloride in tablets by spectrophotometry.

Journal: Hindustan antibiotics bulletin 20070201

Title: Preparative HPLC separation of bambuterol enantiomers and stereoselective inhibition of human cholinesterases.

Journal: Analytical and bioanalytical chemistry 20060801

Title: Irrational combination of montelukast and bambuterol for management of childhood asthma.

Journal: Indian pediatrics 20060801

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Structure-inhibition relationships in the interaction of butyrylcholinesterase with bambuterol, haloxon and their leaving groups.

Journal: Chemico-biological interactions 20051215

Title: Quantification of bambuterol hydrochloride in a formulated product using solid-state NMR.

Journal: Journal of pharmaceutical and biomedical analysis 20050810

Title: Development and validation of HPLC methods for the enantioselective analysis of bambuterol and albuterol.

Journal: Journal of pharmaceutical and biomedical analysis 20050104

Title: Effects of acetylcholinesterase and butyrylcholinesterase inhibition on breathing in mice adapted or not to reduced acetylcholinesterase.

Journal: Pharmacology, biochemistry, and behavior 20050101

Title: Interaction of human butyrylcholinesterase variants with bambuterol and terbutaline.

Journal: Journal of enzyme inhibition and medicinal chemistry 20040401

Title: [Study on bioequivalence of domestic bambuterol capsules and imported tablets by high performance capillary zone electrophoresis].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20031201

Title: Effect of terbutaline and bambuterol on immediate-type allergic skin responses and mediator release in human skin.

Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20030901

Title: Respiratory survival mechanisms in acetylcholinesterase knockout mouse.

Journal: The European journal of neuroscience 20030901

Title: Clinical-pharmacokinetic aspects of prolonged effect duration as illustrated by beta2-agonists.

Journal: European journal of clinical pharmacology 20020701

Title: [Determination of bambuterol in human plasma by liquid chromatography-electrospray tandem mass spectrometry: application to pharmacokinetic study].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20011001

Title: [Rapid analysis of terbutaline by combined solid phase extraction/liquid chromatography tandem mass spectrometry].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20010901

Title: [Bioequivalence of bambuteral and its metabolites terbutaline after oral bambuteral tablet in healthy volunteers by HPLC/MS].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20010501

Title: Age- and gender-specific asthma death rates in patients taking long-acting beta2-agonists: prescription event monitoring pharmacosurveillance studies.

Journal: Drug safety 20010101

Title: Oral bambuterol compared to inhaled salmeterol in patients with partially reversible chronic obstructive pulmonary disease.

Journal: European journal of clinical pharmacology 19990101

Title: Can oral beta2 agonists cause heart failure?

Journal: Lancet (London, England) 19981003

Title: Risk of non-fatal cardiac failure and ischaemic heart disease with long acting beta 2 agonists.

Journal: Thorax 19980701

Title: Therapeutic equivalence between bambuterol, 10 mg once daily, and terbutaline controlled release, 5 mg twice daily, in mild to moderate asthma.

Journal: The European respiratory journal 19931101

Title: Tremor in healthy volunteers after bambuterol and terbutaline CR-tablets.

Journal: European journal of clinical pharmacology 19930101

Title: Bambuterol, From Wikipedia

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Tags:81732-46-9 Molecular Formula|81732-46-9 MDL|81732-46-9 SMILES|81732-46-9 3-[2-(tert-butylamino)-1-hydroxyethyl]-5-[(dimethylcarbamoyl)oxy]phenyl N,N-dimethylcarbamate hydrochloride