[1]Farmaco,EdizioneScientifica,1986,vol.41,#1,p.69-79
[2]Patent:US4411909,1983,A,
84611-23-4
[1]Farmaco,EdizioneScientifica,1986,vol.41,p.69-79
[1]Farmaco,EdizioneScientifica,1986,vol.41,p.69-79
[2]Patent:US4411909,1983,A
[1]Farmaco,EdizioneScientifica,1986,vol.41,p.69-79
[1]Farmaco,EdizioneScientifica,1986,vol.41,p.69-79
[1]Patent:WO2014/174421,2014,A2.Locationinpatent:Paragraph00101;00102
Title: Erdosteine protects HEI-OC1 auditory cells from cisplatin toxicity through suppression of inflammatory cytokines and induction of Nrf2 target proteins.
Journal: Toxicology and applied pharmacology 20151015
Title: Effects of erdosteine on cyclosporin-A-induced nephrotoxicity.
Journal: Human & experimental toxicology 20120601
Title: Effects of erdosteine on hemostasis: an experimental study.
Journal: Human & experimental toxicology 20120601
Title: Antioxidant pharmacological therapies for COPD.
Journal: Current opinion in pharmacology 20120601
Title: Pharmacological antioxidant strategies as therapeutic interventions for COPD.
Journal: Biochimica et biophysica acta 20120501
Title: Is intratympanic injection of erdosteine protective against cisplatin-induced ototoxicity?
Journal: Neurotoxicity research 20120401
Title: Protective effect of erdosteine against cisplatin-induced ototoxicity in a guinea pig model.
Journal: Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 20120401
Title: Caffeic acid phenethyl ester protects 661W cells from H2O2-mediated cell death and enhances electroretinography response in dim-reared albino rats.
Journal: Molecular vision 20120101
Title: Severe drug hypersensitivity induced by erdosteine and doxofylline as confirmed by patch and lymphocyte transformation tests: a case report.
Journal: Journal of investigational allergology & clinical immunology 20120101
Title: Inhibition of gene expression of organic cation/carnitine transporter and antioxidant enzymes in oxazaphosphorines-induced acute cardiomyopathic rat models.
Journal: Oxidative medicine and cellular longevity 20120101
Title: Dual effects of erdosteine on hemostasis via its different metabolites in young rats.
Journal: Human & experimental toxicology 20111001
Title: Comparison of the effects of N-acetyl cysteine and erdosteine in rats with renal injury caused by paracetamol intoxication.
Journal: Human & experimental toxicology 20110901
Title: The protective effect of erdosteine on radiocontrast induced nephrotoxicity in rats.
Journal: Environmental toxicology 20110801
Title: [ Erdosteine (Mucodox), oral administration].
Journal: Journal de pharmacie de Belgique 20110601
Title: Protective effects of erdosteine on amikacin induced visual evoked potentials and lipid peroxidation alterations.
Journal: Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20110401
Title: Effects of erdosteine on cyclosporine-A-induced hepatotoxicity in rats.
Journal: Drug and chemical toxicology 20110101
Title: Erdosteine affects eicosanoid production in COPD.
Journal: International journal of clinical pharmacology and therapeutics 20110101
Title: Prevention of pulmonary complications of pneumoperitoneum in rats.
Journal: Journal of cardiothoracic surgery 20110101
Title: Doxorubicin induced nephrotoxicity: protective effect of nicotinamide.
Journal: International journal of cell biology 20110101
Title: Prevention of hepatorenal toxicity with Sonchus asper in gentamicin treated rats.
Journal: BMC complementary and alternative medicine 20110101
Title: Protective effect of erdosteine metabolite I against hydrogen peroxide-induced oxidative DNA-damage in lung epithelial cells.
Journal: Arzneimittel-Forschung 20110101
Title: Effects of sulphurous water on human neutrophil elastase release.
Journal: Therapeutic advances in respiratory disease 20101201
Title: Combination antioxidant effect of α-tocoferol and erdosteine in ischemia-reperfusion injury in rat model.
Journal: International urology and nephrology 20100901
Title: Beneficial effect of erdosteine on methotrexate-induced testicular toxicity in mice.
Journal: Toxicology and industrial health 20100801
Title: Exaggerated liver injury induced by renal ischemia reperfusion in diabetes: effect of exenatide.
Journal: Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association 20100701
Title: Effect of the mucolytic erdosteine on the success rate of PPI-based first-line triple therapy for Helicobacter pylori eradication: a prospective, double-blind, randomized, placebo-controlled study.
Journal: Scandinavian journal of gastroenterology 20100601
Title: The therapeutic efficacy of erdosteine in the treatment of chronic obstructive bronchitis: a meta-analysis of individual patient data.
Journal: Pulmonary pharmacology & therapeutics 20100401
Title: Effectiveness of erdosteine, a second generation mucolytic agent, in children with acute rhinosinusitis: a randomized, placebo controlled, double-blinded clinical study.
Journal: Acta paediatrica (Oslo, Norway : 1992) 20100401
Title: Cardiotoxicity of anticancer drugs: the need for cardio-oncology and cardio-oncological prevention.
Journal: Journal of the National Cancer Institute 20100106
Title: Erdosteine in renal ischemia-reperfusion injury: an experimental study in pigs.
Journal: The Journal of veterinary medical science 20100101
Title: Modulation of cytokine and nitric oxide by mesenchymal stem cell transfer in lung injury/fibrosis.
Journal: Respiratory research 20100101
Title: Free radical scavenging activity of erdosteine metabolite I investigated by electron paramagnetic resonance spectroscopy.
Journal: Pharmacology 20100101
Title: Ambroxol - Resurgence of an old molecule as an anti-inflammatory agent in chronic obstructive airway diseases.
Journal: Lung India : official organ of Indian Chest Society 20100101
Title: Association between lung function and exacerbation frequency in patients with COPD.
Journal: International journal of chronic obstructive pulmonary disease 20100101
Title: Doxorubicin toxicity can be ameliorated during antioxidant L-carnitine supplementation.
Journal: Oxidative medicine and cellular longevity 20100101
Title: Molecular, genetic and epigenetic pathways of peroxynitrite-induced cellular toxicity.
Journal: Interdisciplinary toxicology 20091201
Title: The protective effect of erdosteine on vancomycin-induced pancreatic damage in rats.
Journal: Molecular and cellular biochemistry 20091101
Title: Erdosteine and ebselen as useful agents in intestinal ischemia/reperfusion injury.
Journal: The Journal of surgical research 20090801
Title: Protective effect of sulfhydryl-containing antioxidants against ischemia/reperfusion injury of prepubertal rat intestine.
Journal: Journal of gastroenterology and hepatology 20090401
Title: Erdosteine modulates radiocontrast-induced hepatotoxicity in rat.
Journal: Cell biochemistry and function 20090401
Title: Erdosteine: its relevance in COPD treatment.
Journal: Expert opinion on drug metabolism & toxicology 20090301
Title: The protective effect of erdosteine on short-term global brain ischemia/reperfusion injury in rats.
Journal: Progress in neuro-psychopharmacology & biological psychiatry 20090201
Title: Environmental toxicity, redox signaling and lung inflammation: the role of glutathione.
Journal: Molecular aspects of medicine 20090101
Title: [Effects of erdosteine on inflammation and fibrosis in rats with pulmonary fibrosis induced by bleomycin].
Journal: Tuberkuloz ve toraks 20090101
Title: Raft of results energizes researchers.
Journal: IAVI report : newsletter on international AIDS vaccine research 20090101
Title: Simultaneous estimation of Cefixime and Erdosteine in capsule dosage form by spectrophotometric method.
Journal: Hindustan antibiotics bulletin 20090101
Title: Antioxidant therapeutic advances in COPD.
Journal: Therapeutic advances in respiratory disease 20081201
Title: The role for S-carboxymethylcysteine (carbocisteine) in the management of chronic obstructive pulmonary disease.
Journal: International journal of chronic obstructive pulmonary disease 20081201
Title: Erdosteine for COPD exacerbations.
Journal: Drug and therapeutics bulletin 20081001
Title: Erdosteine enhances airway response to salbutamol in patients with mild-to-moderate COPD.
Journal: Therapeutic advances in respiratory disease 20081001
Title: Protective role of caffeic acid phenethyl ester and erdosteine on activities of purine-catabolizing enzymes and level of nitric oxide in red blood cells of isoniazid-administered rats.
Journal: Toxicology and industrial health 20080901
Title: The effects of erdosteine, N-acetylcysteine, and vitamin E on nicotine-induced apoptosis of hippocampal neural cells.
Journal: Journal of cellular biochemistry 20080801
Title: Effects of erdosteine on acetaminophen-induced hepatotoxicity in rats.
Journal: Toxicologic pathology 20080701
Title: High-throughput determination of fudosteine in human plasma by liquid chromatography-tandem mass spectrometry, following protein precipitation in the 96-well plate format.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20080501
Title: The effects of erdosteine on lung injury induced by the ischemia-reperfusion of the hind-limbs in rats.
Journal: The Journal of surgical research 20080401
Title: Antioxidant effect of sulphurous thermal water on human neutrophil bursts: chemiluminescence evaluation.
Journal: Respiration; international review of thoracic diseases 20080101
Title: Changes in blood ROS, e-NO, and some pro-inflammatory mediators in bronchial secretions following erdosteine or placebo: a controlled study in current smokers with mild COPD.
Journal: Pulmonary pharmacology & therapeutics 20080101
Title: Renoprotective effect of erdosteine in rats against gentamicin nephrotoxicity: a comparison of 99mTc-DMSA uptake with biochemical studies.
Journal: Molecular and cellular biochemistry 20080101
Title: Erdosteine: antitussive and anti-inflammatory effects.
Journal: Lung 20080101
Title: [Effects of erdosteine on inflammation and fibrosis in rats with pulmonary fibrosis induced by bleomycin].
Journal: Tuberkuloz ve toraks 20080101
Title: Anti-oxidant inhibition of hyaluronan fragment-induced inflammatory gene expression.
Journal: Journal of inflammation (London, England) 20080101
Title: Antioxidant intervention of smoking-induced lung tumor in mice by vitamin E and quercetin.
Journal: BMC cancer 20080101
Title: Antioxidant systems and oxidative stress in the testes.
Journal: Oxidative medicine and cellular longevity 20080101
Title: Pharmacology and clinical efficacy of erdosteine in chronic obstructive pulmonary disease.
Journal: Expert review of respiratory medicine 20071201
Title: The protective effect of erdosteine against cyclosporine A-induced cardiotoxicity in rats.
Journal: Toxicology 20070924
Title: Erdosteine prevents colonic inflammation through its antioxidant and free radical scavenging activities.
Journal: Digestive diseases and sciences 20070901
Title: Mucoactive agents for airway mucus hypersecretory diseases.
Journal: Respiratory care 20070901
Title: Effectiveness of erdosteine in elderly patients with bronchiectasis and hypersecretion: a 15-day, prospective, parallel, open-label, pilot study.
Journal: Clinical therapeutics 20070901
Title: Future therapeutic treatment of COPD: struggle between oxidants and cytokines.
Journal: International journal of chronic obstructive pulmonary disease 20070901
Title: Bacterial lysate in the prevention of acute exacerbation of COPD and in respiratory recurrent infections.
Journal: International journal of chronic obstructive pulmonary disease 20070901
Title: Examination of lung toxicity, oxidant/antioxidant status and effect of erdosteine in rats kept in coal mine ambience.
Journal: Environmental toxicology and pharmacology 20070901
Title: Protective effects of erdosteine and vitamins C and E combination on ischemia-reperfusion-induced lung oxidative stress and plasma copper and zinc levels in a rat hind limb model.
Journal: Biological trace element research 20070701
Title: Protective effects of erdosteine on doxorubicin-induced hepatotoxicity in rats.
Journal: Archives of medical research 20070501
Title: An overview of erdosteine antioxidant activity in experimental research.
Journal: Pharmacological research 20070401
Title: Erdosteine treatment attenuates oxidative stress and fibrosis in experimental biliary obstruction.
Journal: Pediatric surgery international 20070301
Title: The effects of erdosteine, N-acetylcysteine and vitamin E on nicotine-induced apoptosis of cardiac cells.
Journal: Journal of applied toxicology : JAT 20070101
Title: Clinical effects of erdosteine in the treatment of acute respiratory tract diseases in children.
Journal: International journal of clinical pharmacology and therapeutics 20070101
Title: Erdosteine ameliorates lung injury induced by transient aortic occlusion in rats.
Journal: Cardiovascular journal of Africa 20070101
Title: Regulation of sepsis-induced apoptosis of pulmonary cells by posttreatment of erdosteine and N-aceylcysteine.
Journal: Toxicology 20061207
Title: Pharmacological treatment of chronic obstructive pulmonary disease.
Journal: International journal of chronic obstructive pulmonary disease 20061201
Title: Protective role of erdosteine on vancomycin-induced oxidative stress in rat liver.
Journal: Molecular and cellular biochemistry 20061001
Title: Protective effects of N-acetylcysteine and erdosteine on hemorrhagic shock-induced acute lung injury.
Journal: European journal of emergency medicine : official journal of the European Society for Emergency Medicine 20061001
Title: Erdosteine against acetaminophen induced renal toxicity.
Journal: Molecular and cellular biochemistry 20060701
Title: Oxidative stress and redox regulation of lung inflammation in COPD.
Journal: The European respiratory journal 20060701
Title: Antioxidant therapeutic targets in COPD.
Journal: Current drug targets 20060601
Title: Role of mucolytics in the management of COPD.
Journal: International journal of chronic obstructive pulmonary disease 20060601
Title: Antioxidant therapies in COPD.
Journal: International journal of chronic obstructive pulmonary disease 20060301
Title: The effects of erdosteine, N-acetylcysteine, and vitamin E on nicotine-induced apoptosis of pulmonary cells.
Journal: Toxicology 20060215
Title: Protein oxidation and lipid peroxidation after renal ischemia-reperfusion injury: protective effects of erdosteine and N-acetylcysteine.
Journal: Urological research 20060201
Title: Effects of erdosteine on bleomycin-induced lung fibrosis in rats.
Journal: Molecular and cellular biochemistry 20060101
Title: Comparison of the effects of erdosteine and N-acetylcysteine on apoptosis regulation in endotoxin-induced acute lung injury.
Journal: Journal of applied toxicology : JAT 20060101
Title: Hypobaric-hypoxia-induced pulmonary damage in rats ameliorated by antioxidant erdosteine.
Journal: Acta histochemica 20060101
Title: Effect of metabolite I of erdosteine on the release of human neutrophil elastase.
Journal: Pharmacology 20060101
Title: The protective role of erdosteine on testicular tissue after testicular torsion and detorsion.
Journal: Molecular and cellular biochemistry 20051201
Title: In vivo evidences suggesting the role of oxidative stress in pathogenesis of vancomycin-induced nephrotoxicity: protection by erdosteine.
Journal: Toxicology 20051115
Title: The protective effect of erdosteine against ototoxicity induced by cisplatin in rats.
Journal: European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery 20051001
Title: Protective agent, erdosteine, against cisplatin-induced hepatic oxidant injury in rats.
Journal: Molecular and cellular biochemistry 20051001
Title: The effects of isoniazid on hippocampal NMDA receptors: protective role of erdosteine.
Journal: Molecular and cellular biochemistry 20050901
Title: A combination of budesonide and the SH-metabolite I of erdosteine acts synergistically in reducing chemiluminescence during human neutrophil respiratory burst.
Journal: Pharmacology 20050601
Title: Erdosteine ameliorates PTZ-induced oxidative stress in mice seizure model.
Journal: Brain research bulletin 20050530
Title: Effects of erdosteine on smoking-induced lipid peroxidation in healthy smokers.
Journal: Drugs in R&D 20050101
Title: Attenuation of bleomycin-induced lung fibrosis by oral sulfhydryl containing antioxidants in rats: erdosteine and N-acetylcysteine.
Journal: Pulmonary pharmacology & therapeutics 20050101
Title: Inhibition or knock out of inducible nitric oxide synthase result in resistance to bleomycin-induced lung injury.
Journal: Respiratory research 20050101
Title: Erdosteine ameliorates neurological outcome and oxidative stress due to ischemia/reperfusion injury in rabbit spinal cord.
Journal: European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery 20041001
Title: The effects of erdosteine on the activities of some metabolic enzymes during cisplatin-induced nephrotoxicity in rats.
Journal: Pharmacological research 20040901
Title: Effects of aminoguanidine and antioxidant erdosteine on bleomycin-induced lung fibrosis in rats.
Journal: Nitric oxide : biology and chemistry 20040901
Title: Protective effects of erdosteine on rotenone-induced oxidant injury in liver tissue.
Journal: Toxicology and industrial health 20040901
Title: Inhibitory effects of metabolite I of erdosteine on the generation of nitric oxide and peroxynitrite chemiluminescence by human neutrophils.
Journal: Pharmacology 20040701
Title: Erdosteine prevents bleomycin-induced pulmonary fibrosis in rats.
Journal: European journal of pharmacology 20040628
Title: Sensitive determination of erdosteine in human plasma by use of automated 96-well solid-phase extraction and LC-MS/MS.
Journal: Journal of pharmaceutical and biomedical analysis 20040218
Title: In vivo evidence suggesting a role for purine-catabolizing enzymes in the pathogenesis of cisplatin-induced nephrotoxicity in rats and effect of erdosteine against this toxicity.
Journal: Cell biochemistry and function 20040101
Title: Erdosteine improves oxidative damage in a rat model of renal ischemia-reperfusion injury.
Journal: European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes 20040101
Title: Cisplatin-induced acute renal failure is ameliorated by erdosteine in a dose-dependent manner.
Journal: Journal of applied toxicology : JAT 20040101
Title: Peroxynitrite decomposition catalyst ameliorates renal damage and protein nitration in cisplatin-induced nephrotoxicity in rats.
Journal: BMC pharmacology 20040101
Title: The effect of long-term treatment with erdosteine on chronic obstructive pulmonary disease: the EQUALIFE Study.
Journal: Drugs under experimental and clinical research 20040101
Title: Randomised, controlled trial of N-acetylcysteine for treatment of acute exacerbations of chronic obstructive pulmonary disease [ISRCTN21676344].
Journal: BMC pulmonary medicine 20040101
Title: Erdosteine prevents doxorubicin-induced cardiotoxicity in rats.
Journal: Pharmacological research 20031001
Title: The activities of tissue xanthine oxidase and adenosine deaminase and the levels of hydroxyproline and nitric oxide in rat hearts subjected to doxorubicin: protective effect of erdosteine.
Journal: Toxicology 20030930
Title: Effects of erdosteine treatment against doxorubicin-induced toxicity through erythrocyte and plasma oxidant/antioxidant status in rats.
Journal: Pharmacological research 20030401
Title: Depressant effects of ambroxol and erdosteine on cytokine synthesis, granule enzyme release, and free radical production in rat alveolar macrophages activated by lipopolysaccharide.
Journal: Pharmacology & toxicology 20030401
Title: Oral erdosteine administration attenuates cisplatin-induced renal tubular damage in rats.
Journal: Pharmacological research 20030201
Title: Protective effects of erdosteine against doxorubicin-induced cardiomyopathy in rats.
Journal: Journal of applied toxicology : JAT 20030101
Title: Effects on the reactive oxygen species of erdosteine and its metabolite in vitro.
Journal: Arzneimittel-Forschung 20020101
Title: The combination of the SH metabolite of erdosteine (a mucoactive drug) and ciprofloxacin increases the inhibition of bacterial adhesiveness achieved by ciprofloxacin alone.
Journal: Drugs under experimental and clinical research 20020101
Title: The SH-metabolite I of erdosteine, a mucolytic drug, enhances the inhibitory effect of salbutamol on the respiratory burst of neutrophils.
Journal: Drugs under experimental and clinical research 20020101
Title: Bacterial adhesiveness: effects of the SH metabolite of erdosteine (mucoactive drug) plus clarithromycin versus clarithromycin alone.
Journal: Chemotherapy 20010101
Title: Park JS, et al. Anti-inflammatory Effect of Erdosteine in Lipopolysaccharide-Stimulated RAW 264.7 Cells. Inflammation. 2016 Aug;39(4):1573-81.
Title: Oktar S, et al. Beneficial effect of erdosteine on methotrexate-induced testicular toxicity in mice. Toxicol Ind Health. 2010 Aug;26(7):433-8.
Title: Recipharm’s proprietary molecule Erdosteine recognised as COPD treatment
