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85375-15-1,MFCD01321071
Catalog No.:AA003CV9

85375-15-1 | 1-(4,4-Diphenylbut-3-en-1-yl)piperidine-3-carboxylic acid hydrochloride

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5mg
95%
1 week  
$130.00   $91.00
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10mg
95%
1 week  
$167.00   $117.00
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25mg
95%
1 week  
$282.00   $197.00
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50mg
95%
1 week  
$494.00   $346.00
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100mg
95%
1 week  
$700.00   $490.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA003CV9
Chemical Name:
1-(4,4-Diphenylbut-3-en-1-yl)piperidine-3-carboxylic acid hydrochloride
CAS Number:
85375-15-1
Molecular Formula:
C22H26ClNO2
Molecular Weight:
371.9003
MDL Number:
MFCD01321071
SMILES:
OC(=O)C1CCCN(C1)CCC=C(c1ccccc1)c1ccccc1.Cl
Properties
Properties
 
Form:
Solid  

Computed Properties
 
Complexity:
427  
Covalently-Bonded Unit Count:
2  
Heavy Atom Count:
26  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
6  
Undefined Atom Stereocenter Count:
1  

Downstream Synthesis Route

[1]Ali,FadiaE.;Bondinell,WilliamE.;Dandridge,PenelopeA.;Frazee,JamesS.;Garvey,Eleanor;etal.[JournalofMedicinalChemistry,1985,vol.28,#5,p.653-660]

Literature

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Synthesis of novel gamma-aminobutyric acid (GABA) uptake inhibitors. 5.(1) Preparation and structure-activity studies of tricyclic analogues of known GABA uptake inhibitors.

Journal: Journal of medicinal chemistry 20010621

Title: Jinzenji A, et al. Antiallodynic action of 1-(3-(9H-Carbazol-9-yl)-1-propyl)-4-(2-methyoxyphenyl)-4-piperidinol (NNC05-2090), a betaine/GABA transporter inhibitor. J Pharmacol Sci. 2014;125(2):217-26.

Title: Kreitzer MA, et al. Glutamate modulation of GABA transport in retinal horizontal cells of the skate. J Physiol. 2003 Feb 1;546(Pt 3):717-31.

Title: Barakat L, et al. GAT-1 and reversible GABA transport in Bergmann glia in slices. J Neurophysiol. 2002 Sep;88(3):1407-19.

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SDS
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Tags:85375-15-1 Molecular Formula|85375-15-1 MDL|85375-15-1 SMILES|85375-15-1 1-(4,4-Diphenylbut-3-en-1-yl)piperidine-3-carboxylic acid hydrochloride