Home Amines 86541-74-4
86541-74-4,MFCD00895734
Catalog No.:AA003NXG

86541-74-4 | 2-[(3S)-3-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}-2-oxo-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl]acetic acid hydrochloride

Pack Size
Purity
Availability
Price(USD)
Quantity
  
50mg
98%
in stock  
$6.00   $4.00
- +
100mg
98%
in stock  
$8.00   $6.00
- +
250mg
98%
in stock  
$11.00   $8.00
- +
1g
98%
in stock  
$13.00   $9.00
- +
5g
98%
in stock  
$37.00   $26.00
- +
25g
98%
in stock  
$167.00   $117.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA003NXG
Chemical Name:
2-[(3S)-3-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}-2-oxo-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl]acetic acid hydrochloride
CAS Number:
86541-74-4
Molecular Formula:
C24H29ClN2O5
Molecular Weight:
460.9505
MDL Number:
MFCD00895734
SMILES:
CCOC(=O)[C@@H](N[C@H]1CCc2c(N(C1=O)CC(=O)O)cccc2)CCc1ccccc1.Cl
NSC Number:
758920
Properties
Properties
 
Form:
Solid  
MP:
188-190°C  
Solubility:
DMSO: ~34 mg/mL, soluble  

Computed Properties
 
Complexity:
619  
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
2  
Heavy Atom Count:
32  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
10  

Literature

Title: Utility of urinary aldosterone measurement in quantitating RAAS activation.

Journal: Journal of veterinary pharmacology and therapeutics 20121001

Title: Comparison of the efficacy and safety profiles of two fixed-dose combinations of antihypertensive agents, amlodipine/benazepril versus valsartan/hydrochlorothiazide, in patients with type 2 diabetes mellitus and hypertension: a 16-week, multicenter, randomized, double-blind, noninferiority study.

Journal: Clinical therapeutics 20120801

Title: Effect of peroxisome proliferator activated receptor γ agonist on angiotensin converting enzyme 2 mRNA expression in monocyte-derived macrophages of essential hypertensive patients.

Journal: Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae 20120801

Title: Simultaneous determination of lercanidipine, benazepril and benazeprilat in plasma by LC-MS/MS and its application to a toxicokinetics study.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20120615

Title: Blood pressure effects of high-dose amlodipine-benazepril combination in Black and White hypertensive patients not controlled on monotherapy.

Journal: Drugs in R&D 20120601

Title: Predictors of systolic BP <140 mmHg and systolic BP level by randomly assigned treatment group (benazepril plus amlodipine or hydrochlorothiazide) in the ACCOMPLISH Study.

Journal: Blood pressure 20120401

Title: [Protective effects and mechanisms of xin'ganbao capsule on STZ induced early kidney injury in diabetic rats].

Journal: Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20120401

Title: Renal outcomes in hypertensive Black patients at high cardiovascular risk.

Journal: Kidney international 20120301

Title: [Efficiency of benazepril combined with wind dispelling and dampness removing chinese herbs on stage 3 chronic kidney disease with wind-dampness syndrome: a prospective study].

Journal: Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20120301

Title: Optimized project of traditional Chinese medicine in treating chronic kidney disease stage 3: a multicenter double-blinded randomized controlled trial.

Journal: Journal of ethnopharmacology 20120215

Title: Angiotensin-I converting enzyme inhibitors suppress angiogenesis and growth of esophageal carcinoma xenografts.

Journal: Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus 20120101

Title: Pharmacokinetic profiles of hydrochlorothiazide alone and in combination with benazepril or valsartan in healthy Chinese volunteers: evaluation of the potential interaction.

Journal: International journal of clinical pharmacology and therapeutics 20111201

Title: Survival and echocardiographic data in dogs with congestive heart failure caused by mitral valve disease and treated by multiple drugs: a retrospective study of 21 cases.

Journal: The Canadian veterinary journal = La revue veterinaire canadienne 20111101

Title: [Effects of benazepril and valsartan on erythropoietin levels in patients with essential hypertension].

Journal: Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20111001

Title: Blockade of angiotensin II improves hyperthyroid induced abnormal atrial electrophysiological properties.

Journal: Regulatory peptides 20110808

Title: Meta-analysis of randomized controlled trials on effect of angiotensin-converting enzyme inhibitors on cancer risk.

Journal: The American journal of cardiology 20110715

Title: High level of proteinuria during treatment with renin-angiotensin inhibitors is a strong predictor of renal outcome in nondiabetic kidney disease.

Journal: Journal of clinical pharmacology 20110701

Title: Impact of benazepril on contrast-induced acute kidney injury for patients with mild to moderate renal insufficiency undergoing percutaneous coronary intervention.

Journal: Chinese medical journal 20110701

Title: Renoprotective effects of benazepril: current perspective.

Journal: Expert review of cardiovascular therapy 20110601

Title: Interactions of renin-angiotensin system gene polymorphisms and antihypertensive effect of benazepril in Chinese population.

Journal: Pharmacogenomics 20110501

Title: [The renal protective effect of xinganbao capsule in adriamycin induced nephropathy rats].

Journal: Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20110501

Title: Simultaneous determination of atorvastatin, amlodipine, ramipril and benazepril in human plasma by LC-MS/MS and its application to a human pharmacokinetic study.

Journal: Biomedical chromatography : BMC 20110401

Title: Effects of MTHFR and MS gene polymorphisms on baseline blood pressure and Benazepril effectiveness in Chinese hypertensive patients.

Journal: Journal of human hypertension 20110301

Title: Efficacy and duration of benazepril plus amlodipine or hydrochlorothiazide on 24-hour ambulatory systolic blood pressure control.

Journal: Hypertension (Dallas, Tex. : 1979) 20110201

Title: [Comparison of benazepril monotherapy to amlodipine plus benazepril in the treatment of patients with mild and moderate hypertension: a multicentre, randomized, double-blind, parallel-controlled study].

Journal: Zhonghua xin xue guan bing za zhi 20110101

Title: ECG alert: Wellens syndrome.

Journal: AACN advanced critical care 20110101

Title: Antithrombotic drug therapy for IgA nephropathy: a meta analysis of randomized controlled trials.

Journal: Internal medicine (Tokyo, Japan) 20110101

Title: Antihypertensive and organ-protective effects of benazepril.

Journal: Expert review of cardiovascular therapy 20101201

Title: Effects of add-on fluvastatin therapy in patients with chronic proteinuric nephropathy on dual renin-angiotensin system blockade: the ESPLANADE trial.

Journal: Clinical journal of the American Society of Nephrology : CJASN 20101101

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: Beneficial effect of all-trans retinoic acid (ATRA) on glomerulosclerosis rats via the down-regulation of the expression of alpha-smooth muscle actin: a comparative study between ATRA and benazepril.

Journal: Experimental and molecular pathology 20100801

Title: Effects of benazepril on cardiac fibrosis in STZ-induced diabetic rats.

Journal: Acta cardiologica 20100801

Title: 24-hour ambulatory blood pressure in the ACCOMPLISH trial.

Journal: The New England journal of medicine 20100701

Title: Cardiovascular events during differing hypertension therapies in patients with diabetes.

Journal: Journal of the American College of Cardiology 20100629

Title: [Correlation of angiotensin-converting enzyme 2 gene polymorphism with antihypertensive effects of benazepril].

Journal: Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences 20100618

Title: Comparative efficacy and safety of amlodipine/benazepril combination therapy and amlodipine monotherapy in severe hypertension.

Journal: Journal of human hypertension 20100601

Title: Role of RAS inhibition in the regulation of Cu/Zn-SOD in the cardiac and peripheral arterial beds in humans.

Journal: Clinical pharmacology and therapeutics 20100601

Title: Hypertension: antihypertensive class matters for combination therapy.

Journal: Nature reviews. Cardiology 20100601

Title: ECG of the month. Arrhythmogenic right ventricular cardiomyopathy in a Boxer.

Journal: Journal of the American Veterinary Medical Association 20100501

Title: Renal outcomes with different fixed-dose combination therapies in patients with hypertension at high risk for cardiovascular events (ACCOMPLISH): a prespecified secondary analysis of a randomised controlled trial.

Journal: Lancet (London, England) 20100403

Title: Composite renal endpoints: was ACCOMPLISH accomplished?

Journal: Lancet (London, England) 20100403

Title: Simultaneous determination of amlodipine besylate and benazepril hydrochloride in pharmaceutical dosage form by LC.

Journal: Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20091201

Title: Cardioprotective effects of benazepril, an angiotensin-converting enzyme inhibitor, in an ischaemia-reperfusion model of myocardial infarction in rats.

Journal: Journal of the renin-angiotensin-aldosterone system : JRAAS 20091201

Title: E112D polymorphism in the prolylcarboxypeptidase gene is associated with blood pressure response to benazepril in Chinese hypertensive patients.

Journal: Chinese medical journal 20091020

Title: [Effect of benazepril on atrial cytoskeleton remodeling in the canine atrial fibrillation models].

Journal: Zhonghua yi xue za zhi 20091020

Title: Magnetic resonance imaging left ventricular mass reduction with fixed-dose angiotensin-converting enzyme inhibitor-based regimens in patients with high-risk hypertension.

Journal: Hypertension (Dallas, Tex. : 1979) 20091001

Title: [Effect of combined therapy with bailing capsule and benazepril on urinary albumin excretion rate and C-reactive protein in patients with early diabetic nephropathy].

Journal: Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20090901

Title: ACCOMPLISH the goal: hypertension and beyond.

Journal: Current hypertension reports 20090801

Title: Menopause and ovariectomy cause a low grade of systemic inflammation that may be prevented by chronic treatment with low doses of estrogen or losartan.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20090715

Title: Synergistic attenuation of myocardial fibrosis in spontaneously hypertensive rats by joint treatment with benazepril and candesartan.

Journal: Journal of cardiovascular pharmacology 20090701

Title: Transient tricuspid valve regurgitation following surgical treatment of cor triatriatum dexter in a dog.

Journal: The Journal of small animal practice 20090501

Title: A randomized controlled clinical trial of the use of benazepril and heparin for the treatment of chronic kidney disease in dogs.

Journal: Journal of the American Veterinary Medical Association 20090415

Title: Hypertension: an ACCOMPLISHED regimen for hypertension.

Journal: Nature reviews. Nephrology 20090401

Title: Benazepril plus amlodipine or hydrochlorothiazide for hypertension.

Journal: The New England journal of medicine 20090312

Title: Benazepril plus amlodipine or hydrochlorothiazide for hypertension.

Journal: The New England journal of medicine 20090312

Title: Benazepril plus amlodipine or hydrochlorothiazide for hypertension.

Journal: The New England journal of medicine 20090312

Title: Benazepril, an angiotensin-converting enzyme inhibitor, alleviates renal injury in spontaneously hypertensive rats by inhibiting advanced glycation end-product-mediated pathways.

Journal: Clinical and experimental pharmacology & physiology 20090301

Title: Will the results of the ACCOMPLISH trial affect the recommendations of JNC 8?

Journal: Journal of clinical hypertension (Greenwich, Conn.) 20090201

Title: [Clinical study of the month. The ACCOMPLISH study: challenging the choice of antihypertensive medications in systolic hypertensive patients with high cardiovascular risk].

Journal: Revue medicale de Liege 20090201

Title: Could mycophenolate mofetil combined with benazapril delay tubulointerstitial fibrosis in 5/6 nephrectomized rats?

Journal: Chinese medical journal 20090120

Title: [The ACCOMPLISH trial: are results really unexpected?].

Journal: Revue medicale suisse 20090107

Title: Prolonged cholestasis associated with benazepril therapy.

Journal: The American journal of gastroenterology 20090101

Title: All thiazide-like diuretics are not chlorthalidone: putting the ACCOMPLISH study into perspective.

Journal: Journal of clinical hypertension (Greenwich, Conn.) 20090101

Title: [Is the combination of benazepril and amlodipine more effective in hypertension than the combination of benazepril and hydrochlorothiazide? Results of the ACCOMPLISH trial].

Journal: Kardiologiia 20090101

Title: Efficacy of benazepril hydrochloride to delay the progression of occult dilated cardiomyopathy in Doberman Pinschers.

Journal: Journal of veterinary internal medicine 20090101

Title: Effect of benazepril on survival and cardiac events in dogs with asymptomatic mitral valve disease: a retrospective study of 141 cases.

Journal: Journal of veterinary internal medicine 20090101

Title: Validation of uv derivative spectrophotometric method for determination of benazepril hydrochloride in tablets and evaluation of its stability.

Journal: Acta poloniae pharmaceutica 20090101

Title: Effect of benazepril on survival and cardiac events in dogs with asymptomatic mitral valve disease: A retrospective study of 141 cases.

Journal: Journal of veterinary internal medicine 20090101

Title: Benazepril plus amlodipine or hydrochlorothiazide for hypertension in high-risk patients.

Journal: The New England journal of medicine 20081204

Title: Does it matter how hypertension is controlled?

Journal: The New England journal of medicine 20081204

Title: Intracellular angiotensin II production in diabetic rats is correlated with cardiomyocyte apoptosis, oxidative stress, and cardiac fibrosis.

Journal: Diabetes 20081201

Title: Effects of calcium channel blockers on proteinuria in patients with diabetic nephropathy.

Journal: Journal of clinical hypertension (Greenwich, Conn.) 20081001

Title: Transforming growth factor-beta1 is associated with kidney damage in patients with essential hypertension: renoprotective effect of ACE inhibitor and/or angiotensin II receptor blocker.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20080901

Title: Comparison of cardioprotective effects using salvianolic acid B and benazepril for the treatment of chronic myocardial infarction in rats.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20080901

Title: [Unexpected study data for treatment of hypertension. Combination therapy with a diuretic not imperative].

Journal: MMW Fortschritte der Medizin 20080605

Title: Effects of different ACE inhibitor combinations on albuminuria: results of the GUARD study.

Journal: Kidney international 20080601

Title: An eight-week, multicenter, randomized, double-blind study to evaluate the efficacy and tolerability of fixed-dose amlodipine/benazepril combination in comparison with amlodipine as first-line therapy in chinese patients with mild to moderate hypertension.

Journal: Blood pressure. Supplement 20080601

Title: Development of hypertension and effects of benazepril hydrochloride in a canine remnant kidney model of chronic renal failure.

Journal: The Journal of veterinary medical science 20080501

Title: Angioedema of the tongue.

Journal: CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20080422

Title: [Amlodipine is the better partner].

Journal: MMW Fortschritte der Medizin 20080417

Title: [Effect of treatment in 39 patients with diabetic nephropathy by safflor yellow and benazepril in combination].

Journal: Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20080401

Title: Dual blockade of the rennin-angiotensin system versus maximal recommended dose of angiotensin II receptor blockade in chronic glomerulonephritis.

Journal: Clinical and experimental nephrology 20080201

Title: Intron-2 conversion polymorphism of the aldosterone synthase gene and the antihypertensive response to angiotensin-converting enzyme inhibitors.

Journal: Journal of hypertension 20080201

Title: [Effect of benazepril on the VEGF and MVD in the remnant kidney of 5/6 subtotal nephrectomized rats].

Journal: Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20080101

Title: Compliance with antihypertensive therapy in the elderly: a comparison of fixed-dose combination amlodipine/benazepril versus component-based free-combination therapy.

Journal: American journal of cardiovascular drugs : drugs, devices, and other interventions 20080101

Title: Concerns about 'Comparative adverse cardiac effects of pimobendan and benazepril monotherapy in dogs with mild degenerative mitral valve disease: a prospective, controlled, blinded and randomized study'.

Journal: Journal of veterinary internal medicine 20080101

Title: Concerns about 'Comparative adverse cardiac effects of pimobendan and benazepril monotherapy in dogs with mild degenerative mitral valve disease'.

Journal: Journal of veterinary internal medicine 20080101

Title: Effect of benazepril on survival and cardiac events in dogs with asymptomatic mitral valve disease: a retrospective study of 141 cases.

Journal: Journal of veterinary internal medicine 20080101

Title: Racial differences in medication compliance and healthcare utilization among hypertensive Medicaid recipients: fixed-dose vs free-combination treatment.

Journal: Ethnicity & disease 20080101

Title: Effect of pimobendan on case fatality rate in Doberman Pinschers with congestive heart failure caused by dilated cardiomyopathy.

Journal: Journal of veterinary internal medicine 20080101

Title: Combination therapy with amlodipine/benazapril (CCB/ACEI) superior to hydrochlorothiazide/benazapril in high-risk hypertensive patients.

Journal: Cardiovascular journal of Africa 20080101

Title: Predictors of blood pressure response to intensified and fixed combination treatment of hypertension: the ACCOMPLISH study.

Journal: Blood pressure 20080101

Title: A stunning day in hypertension research - Results of ONTARGET, ACCOMPLISH and HYVET.

Journal: Blood pressure 20080101

Title: Comparison of cardioprotective effects of salvianolic acid B and benazepril on large myocardial infarction in rats.

Journal: Pharmacological reports : PR 20080101

Title: Effect of pimobendan or benazepril hydrochloride on survival times in dogs with congestive heart failure caused by naturally occurring myxomatous mitral valve disease: the QUEST study.

Journal: Journal of veterinary internal medicine 20080101

Title: Renal hemodynamics and renoprotection.

Journal: Nephron. Clinical practice 20080101

Title: The diabetes subgroup baseline characteristics of the Avoiding Cardiovascular Events Through Combination Therapy in Patients Living With Systolic Hypertension (ACCOMPLISH) trial.

Journal: Journal of the cardiometabolic syndrome 20080101

Title: Merit of Astragalus polysaccharide in the improvement of early diabetic nephropathy with an effect on mRNA expressions of NF-kappaB and IkappaB in renal cortex of streptozotoxin-induced diabetic rats.

Journal: Journal of ethnopharmacology 20071203

Title: [Effects of benazepril and valsartan alone or in combination on proteinuria in chronic glomerular disease].

Journal: Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue 20071201

Title: Combined therapy of rhein and benazepril on the treatment of diabetic nephropathy in db/db mice.

Journal: Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 20071001

Title: Effects of benazepril hydrochloride in cats with experimentally induced or spontaneously occurring chronic renal failure.

Journal: The Journal of veterinary medical science 20071001

Title: [Effect of atorvastatin on carotid intima-medial of thickness of primary hypertension patients of Han nationality in China].

Journal: Zhonghua yi xue za zhi 20070821

Title: [Clinical observation on treatment of diabetic nephropathy with Chinese drugs combined with benazepril].

Journal: Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20070801

Title: [Clinical observation on treatment of hypertension (yin-deficiency with sthenic-yang syndrome type) with Zhongfu Hypotension Capsule].

Journal: Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20070801

Title: Effect of benazepril on heart rate turbulence in patients with dilated cardiomyopathy.

Journal: Clinical and experimental pharmacology & physiology 20070701

Title: Renoprotection of Optimal Antiproteinuric Doses (ROAD) Study: a randomized controlled study of benazepril and losartan in chronic renal insufficiency.

Journal: Journal of the American Society of Nephrology : JASN 20070601

Title: Benazepril slows progression of renal dysfunction in patients with non-diabetic renal disease.

Journal: Nephrology (Carlton, Vic.) 20070601

Title: IgACE: a placebo-controlled, randomized trial of angiotensin-converting enzyme inhibitors in children and young people with IgA nephropathy and moderate proteinuria.

Journal: Journal of the American Society of Nephrology : JASN 20070601

Title: Benazepril induced isolated visceral angioedema: a rare and under diagnosed adverse effect of angiotensin converting enzyme inhibitors.

Journal: International journal of cardiology 20070531

Title: Simultaneous and rapid quantitation of benazepril and benazeprilat in human plasma by high performance liquid chromatography with ultraviolet detection.

Journal: Journal of pharmaceutical and biomedical analysis 20070509

Title: Urinary neutrophil gelatinase-associated lipocalin (NGAL) is an early biomarker for renal tubulointerstitial injury in IgA nephropathy.

Journal: Clinical immunology (Orlando, Fla.) 20070501

Title: Clinical evaluation of imidapril in congestive heart failure in dogs: results of the EFFIC study.

Journal: The Journal of small animal practice 20070501

Title: The effects of high-dose amlodipine/benazepril combination therapies on blood pressure reduction in patients not adequately controlled with amlodipine monotherapy.

Journal: Blood pressure. Supplement 20070301

Title: Association between angiotensinogen, angiotensin II receptor genes, and blood pressure response to an angiotensin-converting enzyme inhibitor.

Journal: Circulation 20070213

Title: Baseline characteristics in the Avoiding Cardiovascular events through Combination therapy in Patients Living with Systolic Hypertension (ACCOMPLISH) trial: a hypertensive population at high cardiovascular risk.

Journal: Blood pressure 20070101

Title: ACE Inhibitor in the treatment of cutaneous and lymphatic sarcoidosis.

Journal: American journal of clinical dermatology 20070101

Title: Exceptional early blood pressure control rates: the ACCOMPLISH trial.

Journal: Blood pressure 20070101

Title: Comparative adverse cardiac effects of pimobendan and benazepril monotherapy in dogs with mild degenerative mitral valve disease: a prospective, controlled, blinded, and randomized study.

Journal: Journal of veterinary internal medicine 20070101

Title: Prognostic factors in cats with chronic kidney disease.

Journal: Journal of veterinary internal medicine 20070101

Title: Efficacy and safety of olmesartan medoxomil and hydrochlorothiazide compared with benazepril and amlodipine besylate.

Journal: American journal of cardiovascular drugs : drugs, devices, and other interventions 20070101

Title: Angiotensin-converting enzyme (ACE) inhibitor-associated angioedema of the stomach and small intestine: a case report.

Journal: The Mount Sinai journal of medicine, New York 20061201

Title: Angiotensin II type 2 receptor expression after vascular injury: differing effects of angiotensin-converting enzyme inhibition and angiotensin receptor blockade.

Journal: Hypertension (Dallas, Tex. : 1979) 20061101

Title: A randomized, double-blind trial comparing the effects of amlodipine besylate/benazepril HCl vs amlodipine on endothelial function and blood pressure.

Journal: Journal of clinical hypertension (Greenwich, Conn.) 20061001

Title: [Expression of connective tissue growth factor in cardiomyocyte of young rats with heart failure and benazepril intervention].

Journal: Zhonghua er ke za zhi = Chinese journal of pediatrics 20061001

Title: Isolation and characterization of benazepril unknown impurity by chromatographic and spectroscopic methods.

Journal: Journal of pharmaceutical and biomedical analysis 20060926

Title: Impact of Lotensin and Salviae on the changes of TGF-beta1 and its receptors in a rat model of chronic cyclosporine-induced nephropathy.

Journal: Transplantation proceedings 20060901

Title: Formal synthesis of the ACE inhibitor benazepril x HCl via an asymmetric aza-Michael reaction.

Journal: Molecules (Basel, Switzerland) 20060823

Title: Combined AGE inhibition and ACEi decreases the progression of established diabetic nephropathy in B6 db/db mice.

Journal: Kidney international 20060801

Title: Impact of renin angiotensin system blockade on night to day blood pressure ratio in diabetic nephropathy.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20060701

Title: Benazepril combined with either amlodipine or hydrochlorothiazide is more effective than monotherapy for blood pressure control and prevention of end-organ injury in hypertensive Dahl rats.

Journal: Journal of cardiovascular pharmacology 20060701

Title: Benazepril increases feed intake and body weight in healthy growing cats.

Journal: Journal of veterinary pharmacology and therapeutics 20060601

Title: Therapeutic conversion from fosinopril to benazepril at a Veterans Affairs medical center.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20060601

Title: Associations between CYP11B2 gene polymorphisms and the response to angiotensin-converting enzyme inhibitors.

Journal: Clinical pharmacology and therapeutics 20060601

Title: [Effects of Astragalus injection on renal tubular function in patients with IgA nephropathy].

Journal: Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20060601

Title: Effects of benazepril on renal function and kidney expression of matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 in diabetic rats.

Journal: Chinese medical journal 20060520

Title: Development and validation of a liquid chromatographic/electrospray ionization mass spectrometric method for the determination of benazepril, benazeprilat and hydrochlorothiazide in human plasma.

Journal: Journal of mass spectrometry : JMS 20060501

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Benazepril and subclinical feline hypertrophic cardiomyopathy: a prospective, blinded, controlled study.

Journal: The Canadian veterinary journal = La revue veterinaire canadienne 20060501

Title: Beneficial effects of combined benazepril-amlodipine on cardiac nitric oxide, cGMP, and TNF-alpha production after cardiac ischemia.

Journal: Journal of cardiovascular pharmacology 20060501

Title: [What is your diagnosis?].

Journal: Praxis 20060412

Title: Benazepril for advanced chronic renal insufficiency.

Journal: The New England journal of medicine 20060406

Title: Acute oxcarbazepine, benazepril, and hydrochlorothiazide overdose with alcohol.

Journal: Therapeutic drug monitoring 20060401

Title: Benazepril hydrochloride: effects of particle size on tablet properties.

Journal: Die Pharmazie 20060401

Title: Angiotensin-converting enzyme inhibitors as a cause of unilateral tongue angioedema in a 68-year-old woman.

Journal: The American journal of emergency medicine 20060301

Title: Efficacy and safety of benazepril for advanced chronic renal insufficiency.

Journal: The New England journal of medicine 20060112

Title: Optimizing ACE-inhibitor therapy for chronic kidney disease.

Journal: The New England journal of medicine 20060112

Title: [Effects of Tangshenling Mixture and benazepril on rats with diabetic nephropathy and its mechanism].

Journal: Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20060101

Title: A five-year comparison of the renal protective effects of angiotensin-converting enzyme inhibitors and angiotensin receptor blockers in patients with non-diabetic nephropathy.

Journal: Internal medicine (Tokyo, Japan) 20060101

Title: A review of the efficacy of fixed-dose combinations olmesartan medoxomil/hydrochlorothiazide and amlodipine besylate/benazepril in factorial design studies.

Journal: American journal of cardiovascular drugs : drugs, devices, and other interventions 20060101

Title: Efficacy of combination therapy with amlodipine besylate/benazepril hydrochloride for lowering systolic blood pressure in stage 2 hypertension.

Journal: The American journal of geriatric cardiology 20060101

Title: An open-label, randomized, controlled, 4-week comparative clinical trial of barnidipine hydrochloride, a calcium-channel blocker, and benazepril, an angiotensin-converting enzyme inhibitor, in Chinese patients with renal parenchymal hypertension.

Journal: The Journal of international medical research 20060101

Title: Clinical efficacy of pimobendan versus benazepril for the treatment of acquired atrioventricular valvular disease in dogs.

Journal: Journal of the American Animal Hospital Association 20060101

Title: Proteinuria in chronic kidney disease in cats--prognostic marker or therapeutic target?

Journal: Journal of veterinary internal medicine 20060101

Title: Tolerability and efficacy of benazepril in cats with chronic kidney disease.

Journal: Journal of veterinary internal medicine 20060101

Title: Evaluation of the clinical efficacy of benazepril in the treatment of chronic renal insufficiency in cats.

Journal: Journal of veterinary internal medicine 20060101

Title: Orolingual angioedema associated with ACE inhibitor use after rtPA treatment of acute stroke.

Journal: Neurology 20051227

Title: Effect of tepoxalin on renal function in healthy dogs receiving an angiotensin-converting enzyme inhibitor.

Journal: Journal of veterinary pharmacology and therapeutics 20051201

Title: Triple vasopeptidase inhibition normalizes blood pressure in conscious, unrestrained, and spontaneously hypertensive rats.

Journal: American journal of hypertension 20051201

Title: T1198C polymorphism of the angiotensinogen gene and antihypertensive response to angiotensin-converting enzyme inhibitors.

Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20051201

Title: A new ATP-sensitive potassium channel opener protects the kidney from hypertensive damage in spontaneously hypertensive rats.

Journal: The Journal of pharmacology and experimental therapeutics 20051101

Title: Efficacy of combination therapy for systolic blood pressure in patients with severe systolic hypertension: the Systolic Evaluation of Lotrel Efficacy and Comparative Therapies (SELECT) study.

Journal: Journal of clinical hypertension (Greenwich, Conn.) 20051101

Title: [Effects of benazepril combined with valsartan on congestive heart failure].

Journal: Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 20051101

Title: [Influence of alcohol consumption on effectiveness of antihypertensive in male patients with essential hypertension].

Journal: Wei sheng yan jiu = Journal of hygiene research 20051101

Title: Stability indicating RP-HPLC method for simultaneous determination of amlodipine and benazepril hydrochloride from their combination drug product.

Journal: Journal of pharmaceutical and biomedical analysis 20050901

Title: [The AGT genotype affects the antihypertensive effects of benazepril].

Journal: Zhonghua xin xue guan bing za zhi 20050901

Title: A common haplotype on methylenetetrahydrofolate reductase gene modifies the effect of angiotensin-converting enzyme inhibitor on blood pressure in essential hypertension patients--a family-based association study.

Journal: Clinical and experimental hypertension (New York, N.Y. : 1993) 20050801

Title: [Can angiotensin-converting enzyme inhibitor be used in chronic kidney disease patients with serum creatinine level greater than 266 micromol/L?].

Journal: Zhonghua nei ke za zhi 20050801

Title: Chronic myocardial infarction due to arteriosclerosis of coronary arteries followed by acute thromboembolism of caudal abdominal aorta in a cat.

Journal: The Journal of veterinary medical science 20050601

Title: [Effect of simvastatin on cardiac fibrosis in patients with essential hypertension].

Journal: Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20050601

Title: Ouabain-like compound changes rapidly on physical exercise in humans and dogs: effects of beta-blockade and angiotensin-converting enzyme inhibition.

Journal: Hypertension (Dallas, Tex. : 1979) 20050501

Title: Comparison of antihypertensive effects of an angiotensin-converting enzyme inhibitor, a calcium antagonist and a diuretic in patients with hypertension not controlled by angiotensin receptor blocker monotherapy.

Journal: Journal of hypertension 20050401

Title: [Influence of angiotensin-converting enzyme gene polymorphism on the anti-proteinuria efficacy of angiotensin-converting enzyme inhibitor in Han nationality of southern Sichuan province in China].

Journal: Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics 20050401

Title: Protective effects of blocking renin-angiotensin system on the progression of renal injury in glomerulosclerosis.

Journal: Cellular & molecular immunology 20050401

Title: Rationale and design of a study comparing two fixed-dose combination regimens to reduce albuminuria in patients with type II diabetes and hypertension.

Journal: Journal of human hypertension 20050201

Title: The Avoiding Cardiovascular events through COMbination therapy in Patients Living with Systolic Hypertension (ACCOMPLISH) trial: a comparison of first-line combination therapies.

Journal: Expert opinion on pharmacotherapy 20050201

Title: HPTLC method for the simultaneous determination of amlodipine and benazepril in their formulations.

Journal: Journal of chromatographic science 20050201

Title: Simultaneous determination of benazepril hydrochloride and benazeprilat in plasma by high-performance liquid chromatography/electrospray-mass spectrometry.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050125

Title: Associations of baseline blood pressure levels and efficacy of Benazepril treatment with interaction of alpha-adducin and ACE gene polymorphisms in hypertensives.

Journal: Clinical and experimental hypertension (New York, N.Y. : 1993) 20050101

Title: A study of the relationships between angiotensin- converting enzyme gene, chymase gene polymorphisms, pharmacological treatment with ACE inhibitor and regression of left ventricular hypertrophy in essential hypertension patients treated with benazepril.

Journal: Annals of human biology 20050101

Title: Effect of fixed-dose ACE-inhibitor/calcium channel blocker combination therapy vs. ACE-inhibitor monotherapy on arterial compliance in hypertensive patients with type 2 diabetes.

Journal: Preventive cardiology 20050101

Title: Renoprotective effect of benazepril on diabetic nephropathy mediated by P42/44MAPK.

Journal: Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20050101

Title: Low-dose dual blockade of the renin-angiotensin system improves tubular status in non-diabetic proteinuric patients.

Journal: Scandinavian journal of urology and nephrology 20050101

Title: Changes of expressions of VEGF, bFGF, and angiogenesis, and effect of benazepril, bFGF on angiogenesis in acute myocardial infarction model of the rabbits.

Journal: Biomedical and environmental sciences : BES 20041201

Title: [Effect of the polymorphism of the angiotensin-converting enzyme gene on the drug treatment in patients with chronic heart failure].

Journal: Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20041201

Title: Class effect of angiotensin-converting enzyme inhibitors on prevention of myocardial infarction.

Journal: The American journal of cardiology 20041101

Title: [Chronic hyperplastic laryngitis following treatment of hypertension with angiotensin converting enzyme-inhibitor].

Journal: HNO 20041101

Title: Triple vasopeptidase inhibition of angiotensin-converting enzyme/neutral endopeptidase/endothelin-converting enzyme activities on the hemodynamic profile of chronically instrumented unrestrained conscious spontaneously hypertensive rats.

Journal: Journal of cardiovascular pharmacology 20041101

Title: [Renoprotective effects of matrine on experimental glomerulosclerosis in rats].

Journal: Zhonghua er ke za zhi = Chinese journal of pediatrics 20041001

Title: The effect of penetration enhancers on drug delivery through skin: a QSAR study.

Journal: Journal of controlled release : official journal of the Controlled Release Society 20040914

Title: [Association between angiotensin converting enzyme gene, chymase gene and regression of left ventricular hypertrophy in patients treated with angiotensin converting enzyme inhibitors].

Journal: Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi 20040901

Title: Renal synthesis of urokinase type-plasminogen activator, its receptor, and plasminogen activator inhibitor-1 in diabetic nephropathy in rats: modulation by angiotensin-converting-enzyme inhibitor.

Journal: The Journal of laboratory and clinical medicine 20040801

Title: Beta2 adrenergic receptor gene Arg16Gly polymorphism is associated with therapeutic efficacy of benazepril on essential hypertension in Chinese.

Journal: Clinical and experimental hypertension (New York, N.Y. : 1993) 20040801

Title: Amlodipine/benazepril combination therapy for hypertensive patients nonresponsive to benazepril monotherapy.

Journal: American journal of hypertension 20040701

Title: ACE inhibitor and angiotensin type I receptor antagonist in combination reduce renal damage in obese Zucker rats.

Journal: Kidney international 20040601

Title: Initial angiotensin-converting enzyme inhibitor/calcium channel blocker combination therapy achieves superior blood pressure control compared with calcium channel blocker monotherapy in patients with stage 2 hypertension.

Journal: American journal of hypertension 20040601

Title: [Analysis on the trend of long-term change of blood pressure in hypertensive patients treated with benazepril].

Journal: Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi 20040601

Title: [Postmarketing surveillance on Benazepril].

Journal: Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi 20040501

Title: [Effect of different angiotensin converting enzyme inhibitors on coronary collateral circulation].

Journal: Zhonghua yi xue za zhi 20040402

Title: Effects of co-administration of urokinase and benazepril on severe IgA nephropathy.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20040401

Title: Correlation and prediction of moisture-mediated dissolution stability for benazepril hydrochloride tablets.

Journal: Pharmaceutical research 20040401

Title: [Relativity of nuclear factor-kappaB (P65/Rel-A) and angiotensin II type 1 receptor expression in early stage of lesions of adriamycin nephrosis in young rats and the effects of intervention].

Journal: Zhonghua er ke za zhi = Chinese journal of pediatrics 20040401

Title: [Renal parenchymal disease and hypertension].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20040301

Title: Low-dose dual blockade of the renin-angiotensin system in patients with primary glomerulonephritis.

Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 20040201

Title: Combined treatment with an AT1 receptor blocker and angiotensin converting enzyme inhibitor has an additive effect on inhibiting neointima formation via improvement of nitric oxide production and suppression of oxidative stress.

Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20040201

Title: Hypertensive patients from two rural Chinese counties respond differently to benazepril: the Anhui Hypertension Health Care Study.

Journal: Annals of epidemiology 20040201

Title: Effect of antihypertensive monotherapy and combination therapy on arterial distensibility and left ventricular mass.

Journal: American journal of hypertension 20040101

Title: Systemic contact dermatitis due to captopril without cross-sensitivity to fosinopril, quinapril and benazepril.

Journal: Acta dermato-venereologica 20040101

Title: D919G polymorphism of methionine synthase gene is associated with blood pressure response to benazepril in Chinese hypertensive patients.

Journal: Journal of human genetics 20040101

Title: The C677T polymorphism of the methylenetetrahydrofolate reductase gene is associated with the level of decrease on diastolic blood pressure in essential hypertension patients treated by angiotensin-converting enzyme inhibitor.

Journal: Thrombosis research 20040101

Title: Application of the wavelet method for the simultaneous quantitative determination of benazepril and hydrochlorothiazide in their mixtures.

Journal: Journal of AOAC International 20040101

Title: Effects of the combined use of benazepril and valsartan on apoptosis in the kidney of rats with adriamycin-induced nephritic glomerulosclerosis.

Journal: Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20040101

Title: Gene expression profile revealed different effects of angiotensin II receptor blockade and angiotensin-converting enzyme inhibitor on heart failure.

Journal: Journal of cardiovascular pharmacology 20031201

Title: Relationship between polymorphism of the angiotensin-converting enzyme gene and the response to angiotensin-converting enzyme inhibition in hypertensive patients.

Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20031101

Title: [Vasopressin analogue injection as ultimate measure for counteracting severe catecholamine-refractory poisoning by several vasodilators taken with suicidal intent].

Journal: Deutsche medizinische Wochenschrift (1946) 20031017

Title: Investigation of pimobendan versus benazepril in canine myxomatous valvular disease.

Journal: The Veterinary record 20031004

Title: Effect of benazepril amlodipine combination on fibrinolysis in hypertensive diabetic patients.

Journal: European journal of clinical pharmacology 20030801

Title: Pharmacokinetic/pharmacodynamic modelling of the disposition and effect of benazepril and benazeprilat in cats.

Journal: Journal of veterinary pharmacology and therapeutics 20030601

Title: [Study on candidate genes of benazepril related cough in Chinese hypertensives].

Journal: Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi 20030601

Title: Results of a pilot pharmacotherapy quality improvement program using fixed-dose, combination amlodipine/benazepril antihypertensive therapy in a long-term care setting.

Journal: Clinical therapeutics 20030601

Title: An angiotensin converting enzyme inhibitor, benazepril can be transformed to an active metabolite, benazeprilat, by the liver of dogs with ascitic pulmonary heartworm disease.

Journal: The Journal of veterinary medical science 20030601

Title: [Postmarketing surveillance of benazepril-related cough and related risk factors analysis on hypertensives].

Journal: Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi 20030501

Title: Additive effect of ACE inhibition and angiotensin II receptor blockade in type I diabetic patients with diabetic nephropathy.

Journal: Journal of the American Society of Nephrology : JASN 20030401

Title: Effects of valsartan with or without benazepril on blood pressure, angiotensin II, and endoxin in patients with essential hypertension.

Journal: Acta pharmacologica Sinica 20030401

Title: Effect of benazepril addition to amlodipine on ankle oedema and subcutaneous tissue pressure in hypertensive patients.

Journal: Journal of human hypertension 20030301

Title: Effects of combined ACE inhibitor and angiotensin II antagonist treatment in human chronic nephropathies.

Journal: Kidney international 20030301

Title: Correlation of Angiotensin-converting enzyme gene polymorphism with effect of antihypertensive therapy by Angiotensin-converting enzyme inhibitor.

Journal: Journal of cardiovascular pharmacology and therapeutics 20030301

Title: Combination is better than monotherapy with ACE inhibitor or angiotensin receptor antagonist at recommended doses.

Journal: Journal of the renin-angiotensin-aldosterone system : JRAAS 20030301

Title: Linear IgA dermatosis induced by a new angiotensin-converting enzyme inhibitor.

Journal: Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 20030201

Title: [Effect of the compound of traditional Chinese drugs on gene expression of renal endothelin and its receptor of experimental diabetic nephropathy].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20030201

Title: Quantitative determination of benazepril and benazeprilat in human plasma by gas chromatography-mass spectrometry using automated 96-well disk plate solid-phase extraction for sample preparation.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20030105

Title: [Comparative effectiveness of lotensin and capoten in patients with chronic cardiac failure].

Journal: Terapevticheskii arkhiv 20030101

Title: Achieving goal blood pressure in patients with type 2 diabetes: conventional versus fixed-dose combination approaches.

Journal: Journal of clinical hypertension (Greenwich, Conn.) 20030101

Title: [The use of angiotensin-converting enzyme inhibitor benazepril in acute period of myocardial infarction].

Journal: Kardiologiia 20030101

Title: Rationale for combination therapy as initial treatment for hypertension.

Journal: Journal of clinical hypertension (Greenwich, Conn.) 20030101

Title: The first hypertension trial comparing the effects of two fixed-dose combination therapy regimens on cardiovascular events: Avoiding Cardiovascular events through Combination therapy in Patients Living with Systolic Hypertension (ACCOMPLISH).

Journal: Journal of clinical hypertension (Greenwich, Conn.) 20030101

Title: Adherence to antihypertensive therapy with fixed-dose amlodipine besylate/benazepril HCl versus comparable component-based therapy.

Journal: Congestive heart failure (Greenwich, Conn.) 20030101

Title: Effects of antihypertensive drugs on peritoneal vessels in hypertensive dogs with mild renal insufficiency.

Journal: Advances in peritoneal dialysis. Conference on Peritoneal Dialysis 20030101

Title: Efficacy and safety of a therapeutic interchange from high-dose calcium channel blockers to a fixed-dose combination of amlodipine/benazepril in patients with moderate-to-severe hypertension.

Journal: Current hypertension reports 20021201

Title: Selection of the dose of angiotensin converting enzyme inhibitor for patients with diabetic nephropathy depends on the presence or absence of left ventricular hypertrophy.

Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20021101

Title: The effects of antihypertensive agents on the survival rate of polycystic kidney disease in Han:SPRD rats.

Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20021101

Title: [Non-immunologic factor: immunosuppressive drug-induced nephrotoxicity].

Journal: Hinyokika kiyo. Acta urologica Japonica 20021101

Title: Effect of renal insufficiency on the pharmacokinetics and pharmacodynamics of benazepril in cats.

Journal: Journal of veterinary pharmacology and therapeutics 20021001

Title: Using ACE inhibitors appropriately.

Journal: American family physician 20020801

Title: Effects of benazepril, an angiotensin-converting enzyme inhibitor, combined with CGS 35066, a selective endothelin-converting enzyme inhibitor, on arterial blood pressure in normotensive and spontaneously hypertensive rats.

Journal: Clinical science (London, England : 1979) 20020801

Title: Combination therapy of amlodipine/benazepril versus monotherapy of amlodipine in a practice-based setting.

Journal: American journal of hypertension 20020601

Title: Comparison of benazepril-amlodipine and captopril-thiazide combinations in the management of mild-to-moderate hypertension.

Journal: International journal of clinical pharmacology and therapeutics 20020601

Title: [The effects of angiotensin-converting enzyme inhibitor on IgA nephropathy and the influencing factors].

Journal: Zhonghua nei ke za zhi 20020601

Title: [Effects of benazepril on apoptosis in the kidney of diabetic rats].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20020601

Title: [Clinical observation on effect of shenle capsule in treating mesangial proliferating glomerulonephritis].

Journal: Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20020501

Title: Effects of losartan and benazepril on abnormal circadian blood pressure rhythm and target organ damage in SHRSP.

Journal: Clinical and experimental hypertension (New York, N.Y. : 1993) 20020401

Title: Combination therapy with benazepril and oral adsorbent ameliorates progressive renal fibrosis in uremic rats.

Journal: Nephron 20020301

Title: Impact of an ACE inhibitor and calcium antagonist on microalbuminuria and lipid subfractions in type 2 diabetes: a randomised, multi-centre pilot study.

Journal: Journal of human hypertension 20020301

Title: Potentiometric and thermal studies of a coated-wire benazepril-selective electrode.

Journal: Journal of pharmaceutical and biomedical analysis 20020101

Title: Kinetics of the acidic and enzymatic hydrolysis of benazepril HCl studied by LC.

Journal: Journal of pharmaceutical and biomedical analysis 20020101

Title: Pregnancy with prolonged fetal exposure to an angiotensin-converting enzyme inhibitor.

Journal: Journal of perinatology : official journal of the California Perinatal Association 20020101

Title: Combination of hydrochlorothiazide or benazepril with valsartan in hypertensive patients unresponsive to valsartan alone.

Journal: Journal of hypertension 20011101

Title: [CEA comprehensive evaluation for Western and traditional Chinese hypotensive drugs].

Journal: Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20010901

Title: Significance of ACE genotypes and medical treatments in childhood focal glomerulosclerosis.

Journal: Nephron 20010801

Title: Efficacy and safety of a therapeutic interchange from high-dose calcium channel blockers to a fixed-dose combination of amlodipine/benazepril in patients with moderate-to-severe hypertension.

Journal: Journal of human hypertension 20010801

Title: Angiotensin-converting enzyme inhibition potentiates angiotensin II type 1 receptor effects on renal bradykinin and cGMP.

Journal: Hypertension (Dallas, Tex. : 1979) 20010801

Title: Once-daily treatment of patients with hypertension: a placebo-controlled study of amlodipine and benazepril vs amlodipine or benazepril alone.

Journal: Journal of human hypertension 20010701

Title: Valsartan alone or with a diuretic or ACE inhibitor as treatment for African American hypertensives: relation to salt intake.

Journal: American journal of hypertension 20010701

Title: Cilnidipine is as effective as benazepril for control of blood pressure and proteinuria in hypertensive patients with benign nephrosclerosis.

Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20010701

Title: [Serological study on inhibitory function of shenkang injection on glomerular mesangial cell].

Journal: Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20010701

Title: Application of LC and HPTLC-densitometry for the simultaneous determination of benazepril hydrochloride and hydrochlorothiazide.

Journal: Journal of pharmaceutical and biomedical analysis 20010501

Title: Spectrophotometric determination of benazepril hydrochloride and hydrochlorothiazide in binary mixture using second derivative, second derivative of the ratio spectra and chemometric methods.

Journal: Journal of pharmaceutical and biomedical analysis 20010501

Title: Effects of the angiotensin converting enzyme inhibitor benazepril in cats with induced renal insufficiency.

Journal: American journal of veterinary research 20010301

Title: Comparison of the effects of an ACE inhibitor and alphabeta blocker on the progression of renal failure with left ventricular hypertrophy: preliminary report.

Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20010301

Title: Effects of combination of ACE inhibitor and angiotensin receptor blocker on cardiac remodeling, cardiac function, and survival in rat heart failure.

Journal: Circulation 20010102

Title: Voltammetric determination of benazepril and ramipril in dosage forms and biological fluids through nitrosation.

Journal: Journal of AOAC International 20010101

Title: Amlodipine/benazepril: fixed dose combination therapy for hypertension.

Journal: Expert opinion on pharmacotherapy 20010101

Title: Renin-angiotensin system plays an important role in the regulation of water transport in the peritoneum.

Journal: Advances in peritoneal dialysis. Conference on Peritoneal Dialysis 20010101

Title: Treatment of IgA nephropathy with angiotensin converting enzyme inhibitors: design of a prospective randomized multicenter trial.

Journal: Journal of nephrology 20010101

Title: Effect of combination of valsartan with benazepril on blood pressure and left ventricular hypertrophy in SHR.

Journal: Acta pharmacologica Sinica 20001101

Title: ACE DD genotype is more susceptible than ACE II and ID genotypes to the antiproteinuric effect of ACE inhibitors in patients with proteinuric non-insulin-dependent diabetes mellitus.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20001001

Title: Additive hypotensive effect of angiotensin-converting enzyme inhibition and angiotensin-receptor antagonism in essential hypertension.

Journal: Journal of cardiovascular pharmacology 20000601

Title: Lack of evidence of blood pressure-independent protection by renin-angiotensin system blockade after renal ablation.

Journal: Kidney international 20000401

Title: Safety of the combination of valsartan and benazepril in patients with chronic renal disease. European Group for the Investigation of Valsartan in Chronic Renal Disease.

Journal: Journal of hypertension 20000101

Title: Renal protective effects of blocking the intrarenal renin-angiotensin system.

Journal: Hypertension research : official journal of the Japanese Society of Hypertension 19990901

Title: Antiatherogenic effect of angiotensin converting enzyme inhibitor (benazepril) and angiotensin II receptor antagonist (valsartan) in the cholesterol-fed rabbits.

Journal: Atherosclerosis 19990401

Title: [Expression of type I transforming growth factor beta receptor in renal cortex in streptozotocin-induced diabetic rats and the regulation of benazepril].

Journal: Zhonghua nei ke za zhi 19990101

Title: [The effects of blocking intrarenal renin-angiotensin system on the expression of transforming growth factor-beta1 mRNA and extracellular matrix components].

Journal: Zhonghua nei ke za zhi 19990101

Title: Effects of benazepril on insulin resistance and glucose tolerance in uremia.

Journal: Clinical nephrology 19980801

Title: Prevention of renal injury in diabetic MWF rats by angiotensin II antagonism.

Journal: Experimental nephrology 19980101

Title: [The expression of AT1A receptor and its modulation by benazepril in the renal tubulointerstitial lesions induced by ureteral obstruction].

Journal: Zhonghua yi xue za zhi 19970401

Title: Blockade of angiotensin converting enzyme but not of angiotensin AT1 receptors improves glucose tolerance.

Journal: European journal of pharmacology 19970114

Title: [Reduced progression, increased mortality in chronic renal disease after treatment with the angiotensin-converting enzyme inhibitor benazepril].

Journal: Ugeskrift for laeger 19961007

Title: Left ventricular wall stress and sarcoplasmic reticulum Ca(2+)-ATPase gene expression in renal hypertensive rats: dose-dependent effects of ACE inhibition and AT1-receptor blockade.

Journal: Cardiovascular research 19960501

Title: Effect of ACE inhibition by benazepril, enalapril and captopril on chronic and post exercise proteinuria.

Journal: Acta physiologica Hungarica 19960101

Title: Antihypertensive treatment efficacy in type II diabetes mellitus. Dissociation between casual and 24-hour ambulatory blood pressure. Spanish Multicenter Study Group.

Journal: Hypertension (Dallas, Tex. : 1979) 19951201

Title: Early genes induction in spontaneously hypertensive rats left ventricle with angiotensin-converting enzyme inhibitors but not hydralazine.

Journal: Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) 19951201

Title: Improved glucose metabolism following blockade of angiotensin converting enzyme but not angiotensin AT1 receptors.

Journal: European journal of pharmacology 19950825

Title: Fixed combination of benazepril and very low dose hydrochlorothiazide in the treatment of mild to moderate essential hypertension: evaluation by 24-hour non invasive ambulatory blood pressure monitoring.

Journal: International journal of clinical pharmacology and therapeutics 19941101

Title: Angiotensin blockade or calcium antagonists improve endothelial dysfunction in hypertension: studies in perfused mesenteric resistance arteries.

Journal: Journal of cardiovascular pharmacology 19940901

Title: Site-differential gastrointestinal absorption of benazepril hydrochloride in healthy volunteers.

Journal: Pharmaceutical research 19940301

Title: Effects of the single and repeated administration of benazepril on systemic and forearm circulation and cardiac function in hypertensive patients.

Journal: Cardiovascular drugs and therapy 19930401

Title: Pharmacokinetics and pharmacodynamics of benazepril hydrochloride in patients with major proteinuria.

Journal: European journal of clinical pharmacology 19930101

Title: Assessment of left ventricular diastolic function in dilated cardiomyopathy with cine magnetic resonance imaging: effect of an angiotensin converting enzyme inhibitor, benazepril.

Journal: American heart journal 19930101

Title: Effects of once-daily benazepril therapy on exercise tolerance and manifestations of chronic congestive heart failure. The Benazepril Heart Failure Study Group.

Journal: The American journal of cardiology 19920801

Title: Sympathomoderating influence of benazepril in essential hypertension.

Journal: Journal of hypertension 19920401

Title: Short-term metabolic effects of the ACE-inhibitor benazepril in type 2 diabetes mellitus associated with arterial hypertension.

Journal: Diabete & metabolisme 19920101

Title: Safety profile of benazepril in essential hypertension.

Journal: Clinical cardiology 19910801

Title: The pharmacokinetics of benazepril relative to other ACE inhibitors.

Journal: Clinical cardiology 19910801

Title: Benazepril at incremental doses in essential hypertension.

Journal: International journal of clinical pharmacology, therapy, and toxicology 19900201

Title: Glucocorticoids amplify glomerular injury in rats with renal ablation.

Journal: American journal of hypertension 19880101

Title: Hou FF, et al. Efficacy and safety of benazepril for advanced chronic renal insufficiency. N Engl J Med. 2006 Jan 12;354(2):131-40.

Title: Huang XM, et al. Effects of chronotherapy of benazepril on the diurnal profile of RAAS and clock genes in the kidney of 5/6 nephrectomy rats. J Huazhong Univ Sci Technolog Med Sci. 2013 Jun;33(3):368-74.

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Tags:86541-74-4 Molecular Formula|86541-74-4 MDL|86541-74-4 SMILES|86541-74-4 2-[(3S)-3-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}-2-oxo-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl]acetic acid hydrochloride