Title: Activation of peroxisome proliferator-activated receptor α ameliorates perfluorododecanoic acid-induced production of reactive oxygen species in rat liver.
Journal: Archives of toxicology 20160601
Title: Inhibition of PPARα attenuates vimentin phosphorylation on Ser-83 and collapse of vimentin filaments during exposure of rat Sertoli cells in vitro to DBP.
Journal: Reproductive toxicology (Elmsford, N.Y.) 20141201
Title: Sargahydroquinoic acid inhibits TNFα-induced AP-1 and NF-κB signaling in HaCaT cells through PPARα activation.
Journal: Biochemical and biophysical research communications 20140808
Title: Fenofibrate suppresses melanogenesis in B16-F10 melanoma cells via activation of the p38 mitogen-activated protein kinase pathway.
Journal: Chemico-biological interactions 20131005
Title: SIRT1 inhibits NADPH oxidase activation and protects endothelial function in the rat aorta: implications for vascular aging.
Journal: Biochemical pharmacology 20130501
Title: Pretreatment with proteasome inhibitors protects against oxidative injuries via PPARα-dependent and -independent pathways in ARPE-19 cells.
Journal: Investigative ophthalmology & visual science 20120831
Title: Alteration of neuropathic and visceral pain in female C57BL/6J mice lacking the PPAR-α gene.
Journal: Psychopharmacology 20120801
Title: The synthetic cannabinoid R(+)WIN55,212-2 augments interferon-β expression via peroxisome proliferator-activated receptor-α.
Journal: The Journal of biological chemistry 20120720
Title: Effects of palmitoylethanolamide on aqueous humor outflow.
Journal: Investigative ophthalmology & visual science 20120701
Title: Effects of the anandamide uptake blocker AM404 on food intake depend on feeding status and route of administration.
Journal: Pharmacology, biochemistry, and behavior 20120301
Title: OxLDL up-regulates Niemann-Pick type C1 expression through ERK1/2/COX-2/PPARα-signaling pathway in macrophages.
Journal: Acta biochimica et biophysica Sinica 20120201
Title: Peroxisome proliferator-activated receptor activity is involved in the osteoblastic differentiation regulated by bone morphogenetic proteins and tumor necrosis factor-α.
Journal: Molecular and cellular endocrinology 20120102
Title: Chemical cross-linking and high-resolution mass spectrometry to study protein-drug interactions.
Journal: Methods in molecular biology (Clifton, N.J.) 20120101
Title: Fenofibrate down-regulates renal OCT2-mediated organic cation transport via PPARα-independent pathways.
Journal: Drug metabolism and pharmacokinetics 20120101
Title: The role of PPARα in metformin-induced attenuation of mitochondrial dysfunction in acute cardiac ischemia/reperfusion in rats.
Journal: International journal of molecular sciences 20120101
Title: Fenofibrate suppresses growth of the human hepatocellular carcinoma cell via PPARα-independent mechanisms.
Journal: European journal of cell biology 20110801
Title: Regulation mechanism of ABCA1 expression by statins in hepatocytes.
Journal: European journal of pharmacology 20110715
Title: Activation of peroxisome proliferator-activated receptor-alpha stimulates both differentiation and fatty acid oxidation in adipocytes.
Journal: Journal of lipid research 20110501
Title: Activation of peroxisome-proliferator-activated receptors α and γ mediates remote ischemic preconditioning against myocardial infarction in vivo.
Journal: Experimental biology and medicine (Maywood, N.J.) 20110101
Title: Brown adipose tissue responds to cold and adrenergic stimulation by induction of FGF21.
Journal: Molecular medicine (Cambridge, Mass.) 20110101
Title: 13-hydroxy linoleic acid increases expression of the cholesterol transporters ABCA1, ABCG1 and SR-BI and stimulates apoA-I-dependent cholesterol efflux in RAW264.7 macrophages.
Journal: Lipids in health and disease 20110101
Title: Leptin induces hypertrophy through activating the peroxisome proliferator-activated receptor α pathway in cultured neonatal rat cardiomyocytes.
Journal: Clinical and experimental pharmacology & physiology 20101101
Title: Adiponectin-mediated heme oxygenase-1 induction protects against iron-induced liver injury via a PPARα dependent mechanism.
Journal: The American journal of pathology 20101001
Title: Activation of peroxisome proliferator-activated receptor-beta/delta attenuates myocardial ischemia/reperfusion injury in the rat.
Journal: Shock (Augusta, Ga.) 20100801
Title: Fenofibrate induces effective apoptosis in mantle cell lymphoma by inhibiting the TNFalpha/NF-kappaB signaling axis.
Journal: Leukemia 20100801
Title: Resveratrol prevents the impairment of advanced glycosylation end products (AGE) on macrophage lipid homeostasis by suppressing the receptor for AGE via peroxisome proliferator-activated receptor gamma activation.
Journal: International journal of molecular medicine 20100501
Title: An innovative method to study target protein-drug interactions by mass spectrometry.
Journal: Journal of medicinal chemistry 20090514
Title: Inhibition of fatty acid amide hydrolase produces PPAR-alpha-mediated analgesia in a rat model of inflammatory pain.
Journal: British journal of pharmacology 20081201
Title: Exposure to perfluorooctane sulfonate or fenofibrate causes PPAR-alpha dependent transcriptional responses in chicken embryo hepatocytes.
Journal: Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20080801
Title: Inhibition of fatty acid amide hydrolase and cyclooxygenase-2 increases levels of endocannabinoid related molecules and produces analgesia via peroxisome proliferator-activated receptor-alpha in a model of inflammatory pain.
Journal: Neuropharmacology 20080701
Title: Time-dependence of cardiomyocyte differentiation disturbed by peroxisome proliferator-activated receptor alpha inhibitor GW6471 in murine embryonic stem cells in vitro.
Journal: Acta pharmacologica Sinica 20070501
Title: Fatty acid homeostasis and induction of lipid regulatory genes in skeletal muscles of peroxisome proliferator-activated receptor (PPAR) alpha knock-out mice. Evidence for compensatory regulation by PPAR delta.
Journal: The Journal of biological chemistry 20020719
Title: Structural basis for antagonist-mediated recruitment of nuclear co-repressors by PPARalpha.
Journal: Nature 20020214
Title: Xu HE, et al. Structural basis for antagonist-mediated recruitment of nuclear co-repressors by PPARalpha. Nature. 2002 Feb 14;415(6873):813-7.
Title: Abu Aboud O, et al. Inhibition of PPARα induces cell cycle arrest and apoptosis, and synergizes with glycolysisinhibition in kidney cancer cells. PLoS One. 2013 Aug 7;8(8):e71115.
Title: Abu Aboud O, et al. PPARα inhibition modulates multiple reprogrammed metabolic pathways in kidney cancer and attenuates tumor growth. Am J Physiol Cell Physiol. 2015 Jun 1;308(11):C890-8.
