Title: The G protein-coupled oestrogen receptor 1 agonist G-1 disrupts endothelial cell microtubule structure in a receptor-independent manner.
Journal: Molecular and cellular biochemistry 20120701
Title: Effects of a combined treatment with GPR30 agonist G-1 and herceptin on growth and gene expression of human breast cancer cell lines.
Journal: Cancer investigation 20120601
Title: Activation of GPR30 attenuates diastolic dysfunction and left ventricle remodelling in oophorectomized mRen2.Lewis rats.
Journal: Cardiovascular research 20120401
Title: Aberrant ligand-induced activation of G protein-coupled estrogen receptor 1 (GPER) results in developmental malformations during vertebrate embryogenesis.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20120101
Title: G protein-coupled estrogen receptor 1-mediated effects in the rat myometrium.
Journal: American journal of physiology. Cell physiology 20111101
Title: Estrogen receptor GPR30 reduces oxidative stress and proteinuria in the salt-sensitive female mRen2.Lewis rat.
Journal: Hypertension (Dallas, Tex. : 1979) 20111001
Title: Induction of interleukin-10 in the T helper type 17 effector population by the G protein coupled estrogen receptor (GPER) agonist G-1.
Journal: Immunology 20110901
Title: Mechanisms of estradiol-induced insulin secretion by the G protein-coupled estrogen receptor GPR30/GPER in pancreatic beta-cells.
Journal: Endocrinology 20110801
Title: Insulinotropic and antidiabetic effects of 17β-estradiol and the GPR30 agonist G-1 on human pancreatic islets.
Journal: Endocrinology 20110701
Title: Estrogen destabilizes microtubules through an ion-conductivity-independent TRPV1 pathway.
Journal: Journal of neurochemistry 20110601
Title: Vasodilation in response to the GPR30 agonist G-1 is not different from estradiol in the mRen2.Lewis female rat.
Journal: Journal of cardiovascular pharmacology 20110501
Title: GPR30 activation opposes estrogen-dependent uterine growth via inhibition of stromal ERK1/2 and estrogen receptor alpha (ERα) phosphorylation signals.
Journal: Endocrinology 20110401
Title: GPR30 co-localizes with cholinergic neurons in the basal forebrain and enhances potassium-stimulated acetylcholine release in the hippocampus.
Journal: Psychoneuroendocrinology 20110201
Title: The GPER1 agonist G-1 attenuates endothelial cell proliferation by inhibiting DNA synthesis and accumulating cells in the S and G2 phases of the cell cycle.
Journal: Journal of vascular research 20110101
Title: Activation of GPR30 inhibits the growth of prostate cancer cells through sustained activation of Erk1/2, c-jun/c-fos-dependent upregulation of p21, and induction of G(2) cell-cycle arrest.
Journal: Cell death and differentiation 20100901
Title: Signaling via GPR30 protects the myocardium from ischemia/reperfusion injury.
Journal: Surgery 20100801
Title: Expression and signaling of G protein-coupled estrogen receptor 1 (GPER) in rat sertoli cells.
Journal: Biology of reproduction 20100801
Title: Dilation of epicardial coronary arteries by the G protein-coupled estrogen receptor agonists G-1 and ICI 182,780.
Journal: Pharmacology 20100801
Title: Highly efficient synthesis and characterization of the GPR30-selective agonist G-1 and related tetrahydroquinoline analogs.
Journal: Organic & biomolecular chemistry 20100507
Title: Regulation of ERRalpha gene expression by estrogen receptor agonists and antagonists in SKBR3 breast cancer cells: differential molecular mechanisms mediated by g protein-coupled receptor GPR30/GPER-1.
Journal: Molecular endocrinology (Baltimore, Md.) 20100501
Title: Endothelium-dependent relaxation by G protein-coupled receptor 30 agonists in rat carotid arteries.
Journal: American journal of physiology. Heart and circulatory physiology 20100301
Title: The G protein-coupled receptor GPR30 inhibits proliferation of estrogen receptor-positive breast cancer cells.
Journal: Cancer research 20100201
Title: Attenuation of salt-induced cardiac remodeling and diastolic dysfunction by the GPER agonist G-1 in female mRen2.Lewis rats.
Journal: PloS one 20100101
Title: Activation of a novel estrogen receptor, GPER, is cardioprotective in male and female rats.
Journal: American journal of physiology. Heart and circulatory physiology 20091101
Title: Beneficial role of the GPR30 agonist G-1 in an animal model of multiple sclerosis.
Journal: Journal of neuroimmunology 20090929
Title: Chronic treatment with estrogen receptor agonists restores acquisition of a spatial learning task in young ovariectomized rats.
Journal: Hormones and behavior 20090901
Title: Chronic treatment with the G protein-coupled receptor 30 agonist G-1 decreases blood pressure in ovariectomized mRen2.Lewis rats.
Journal: Endocrinology 20090801
Title: Expression of estrogen receptor GPR30 in the rat spinal cord and in autonomic and sensory ganglia.
Journal: Journal of neuroscience research 20090515
Title: Involvement of estradiol-17beta and its membrane receptor, G protein coupled receptor 30 (GPR30) in regulation of oocyte maturation in zebrafish, Danio rario.
Journal: General and comparative endocrinology 20090301
Title: Membrane estrogen receptor regulates experimental autoimmune encephalomyelitis through up-regulation of programmed death 1.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20090301
Title: GPR30 estrogen receptor agonists induce mechanical hyperalgesia in the rat.
Journal: The European journal of neuroscience 20080401
Title: GPR30 contributes to estrogen-induced thymic atrophy.
Journal: Molecular endocrinology (Baltimore, Md.) 20080301
Title: Distribution and characterization of estrogen receptor G protein-coupled receptor 30 in the rat central nervous system.
Journal: The Journal of endocrinology 20070501
Title: G protein-coupled receptor 30 (GPR30) mediates gene expression changes and growth response to 17beta-estradiol and selective GPR30 ligand G-1 in ovarian cancer cells.
Journal: Cancer research 20070215
Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.
Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
Title: Cheng Q, et al. G-1 exerts neuroprotective effects through G protein-coupled estrogen receptor 1 following spinal cord injury in mice. Biosci Rep. 2016 Aug 31;36(4). pii: e00373.
Title: Kurt AH, et al. Oxidative/antioxidative enzyme-mediated antiproliferative and proapoptotic effects of the GPER1 agonist G-1 on lung cancer cells. Oncol Lett. 2015 Nov;10(5):3177-3182.
Title: Chimento A, et al. GPER agonist G-1 decreases adrenocortical carcinoma (ACC) cell growth in vitro and in vivo. Oncotarget. 2015 Aug 7;6(22):19190-203.
