Title: Calpain and JNK pathways participate in isoflurane - induced nucleus translocation of apoptosis-inducing factor in the brain of neonatal rats.
Journal: Toxicology letters 20180315
Title: Redox-control of the alarmin, Interleukin-1α.
Journal: Redox biology 20130101
Title: Temporal dependence of cysteine protease activation following excitotoxic hippocampal injury.
Journal: Neuroscience 20121011
Title: Low-dose methylmercury-induced oxidative stress, cytotoxicity, and tau-hyperphosphorylation in human neuroblastoma (SH-SY5Y) cells.
Journal: Environmental toxicology 20120901
Title: Activity-dependent cleavage of the K-Cl cotransporter KCC2 mediated by calcium-activated protease calpain.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20120815
Title: Calpain induces N-terminal truncation of β-catenin in normal murine liver development: diagnostic implications in hepatoblastomas.
Journal: The Journal of biological chemistry 20120629
Title: Calpain inhibitors exhibit matrix metalloproteinase-2 inhibitory activity.
Journal: Biochemical and biophysical research communications 20120622
Title: Neuroprotective effect of undecylenic acid extracted from Ricinus communis L. through inhibition of μ-calpain.
Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20120512
Title: Ablation of junctin or triadin is associated with increased cardiac injury following ischaemia/reperfusion.
Journal: Cardiovascular research 20120501
Title: Calpain inhibitor MDL 28170 protects against the Ca2+ paradox in rat hearts.
Journal: Clinical and experimental pharmacology & physiology 20120401
Title: Short-duration treatment with the calpain inhibitor MDL-28170 does not protect axonal transport in an in vivo model of traumatic axonal injury.
Journal: Journal of neurotrauma 20120120
Title: A pharmacologically-based array to identify targets of cyclosporine A-induced toxicity in cultured renal proximal tubule cells.
Journal: Toxicology and applied pharmacology 20120115
Title: Calpain activation is involved in acute manganese neurotoxicity in the rat striatum in vivo.
Journal: Experimental neurology 20120101
Title: Inhibition of calpain blocks the phagosomal escape of Listeria monocytogenes.
Journal: PloS one 20120101
Title: Activation of mitochondrial μ-calpain increases AIF cleavage in cardiac mitochondria during ischemia-reperfusion.
Journal: Biochemical and biophysical research communications 20111202
Title: Neuroprotective effects of MAPK/ERK1/2 and calpain inhibitors on lactacystin-induced cell damage in primary cortical neurons.
Journal: Neurotoxicology 20111201
Title: Targeted proteolysis of plectin isoform 1a accounts for hemidesmosome dysfunction in mice mimicking the dominant skin blistering disease EBS-Ogna.
Journal: PLoS genetics 20111201
Title: Calpain mediates pulmonary vascular remodeling in rodent models of pulmonary hypertension, and its inhibition attenuates pathologic features of disease.
Journal: The Journal of clinical investigation 20111101
Title: MDL28170, a calpain inhibitor, affects Trypanosoma cruzi metacyclogenesis, ultrastructure and attachment to Rhodnius prolixus midgut.
Journal: PloS one 20110101
Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.
Journal: Bioorganic & medicinal chemistry letters 20101101
Title: Calpain is involved in cisplatin-induced endothelial injury in an in vitro three-dimensional blood vessel model.
Journal: International journal of oncology 20101101
Title: MDL-28170 has no analgesic effect on CCI induced neuropathic pain in mice.
Journal: Molecules (Basel, Switzerland) 20100427
Title: Ischemia-reperfusion-induced changes in sarcolemmal Na+/K+-ATPase are due to the activation of calpain in the heart.
Journal: Canadian journal of physiology and pharmacology 20100301
Title: Calcium-dependent cleavage of the Na(+)/Ca(2+) exchanger by m-calpain in isolated endoplasmic reticulum.
Journal: Journal of biochemistry 20100201
Title: Calpain inhibition reduces axolemmal leakage in traumatic axonal injury.
Journal: Molecules (Basel, Switzerland) 20091209
Title: Interactions between apoptotic signal transduction and capacitation in human spermatozoa.
Journal: Human reproduction (Oxford, England) 20090901
Title: Mitochondrial micro-calpain is not involved in the processing of apoptosis-inducing factor.
Journal: Experimental neurology 20090801
Title: Over-expression of calpastatin inhibits calpain activation and attenuates myocardial dysfunction during endotoxaemia.
Journal: Cardiovascular research 20090701
Title: Role of GRP78/BiP degradation and ER stress in deoxynivalenol-induced interleukin-6 upregulation in the macrophage.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20090601
Title: Calpain-mediated degradation of G-substrate plays a critical role in retinal excitotoxicity for amacrine cells.
Journal: Journal of neuroscience research 20090501
Title: Calpain-mediated truncation of GSK-3 in post-mortem brain samples.
Journal: Journal of neuroscience research 20090401
Title: Arrested growth of Trypanosoma cruzi by the calpain inhibitor MDL28170 and detection of calpain homologues in epimastigote forms.
Journal: Parasitology 20090401
Title: Participation of mu-calpain in status epilepticus-induced hippocampal injury.
Journal: Brain research bulletin 20090316
Title: mu-Calpain mediated cleavage of the Na+/Ca2+ exchanger in isolated mitochondria under A23187 induced Ca2+ stimulation.
Journal: Archives of biochemistry and biophysics 20090201
Title: Protein Never in Mitosis Gene A Interacting-1 (PIN1) regulates degradation of inducible nitric oxide synthase in endothelial cells.
Journal: American journal of physiology. Cell physiology 20080901
Title: Contribution of NMDA and non-NMDA receptors to in vivo glutamate-induced calpain activation in the rat striatum. Relation to neuronal damage.
Journal: Neurochemical research 20080801
Title: Intraspinal MDL28170 microinjection improves functional and pathological outcome following spinal cord injury.
Journal: Journal of neurotrauma 20080701
Title: Mu-calpain mediates hippocampal neuron death in rats after lithium-pilocarpine-induced status epilepticus.
Journal: Brain research bulletin 20080515
Title: Calpain activation is involved in early caspase-independent neurodegeneration in the hippocampus following status epilepticus.
Journal: Journal of neurochemistry 20080501
Title: Contribution of calpain activation to early stages of hippocampal damage during oxygen-glucose deprivation.
Journal: Brain research 20080227
Title: Intracellular GSH levels rather than ROS levels are tightly related to AMA-induced HeLa cell death.
Journal: Chemico-biological interactions 20080110
Title: Sustained calpain inhibition improves locomotor function and tissue sparing following contusive spinal cord injury.
Journal: Neurochemical research 20071201
Title: A key role for calpains in retinal ganglion cell death.
Journal: Investigative ophthalmology & visual science 20071201
Title: Coherent anti-Stokes Raman scattering imaging of myelin degradation reveals a calcium-dependent pathway in lyso-PtdCho-induced demyelination.
Journal: Journal of neuroscience research 20071001
Title: Specific blockage of ligand-induced degradation of the Ah receptor by proteasome but not calpain inhibitors in cell culture lines from different species.
Journal: Biochemical pharmacology 20070630
Title: Calpain inhibitor MDL-28170 reduces the functional and structural deterioration of corpus callosum following fluid percussion injury.
Journal: Journal of neurotrauma 20070601
Title: Ischemia promotes calpain-mediated degradation of p120-catenin in SH-SY5Y cells.
Journal: Biochemical and biophysical research communications 20070216
Title: A role for the intracellular protease calpain in the activation of store-operated calcium entry in human platelets.
Journal: Cell calcium 20070201
Title: Calpain inhibition stimulates caspase-dependent apoptosis induced by taxol in NIH3T3 cells.
Journal: Experimental cell research 20070115
Title: Microtubule disruption, not calpain-dependent loss of MAP2, contributes to enduring NMDA-induced dendritic dysfunction in acute hippocampal slices.
Journal: Experimental neurology 20061201
Title: Calpain mediates the dioxin-induced activation and down-regulation of the aryl hydrocarbon receptor.
Journal: Molecular pharmacology 20061101
Title: Glutamate-induced protease-mediated loss of plasma membrane Ca2+ pump activity in rat hippocampal neurons.
Journal: Journal of neurochemistry 20060901
Title: Antileishmanial activity of MDL 28170, a potent calpain inhibitor.
Journal: International journal of antimicrobial agents 20060801
Title: Tributyltin-induced cell death is mediated by calpain in PC12 cells.
Journal: Neurotoxicology 20060701
Title: Ischemic preconditioning prevents calpain-mediated impairment of Na+/K+-ATPase activity during early reperfusion.
Journal: Cardiovascular research 20060501
Title: The calpain inhibitor MDL-28170 and the AMPA/KA receptor antagonist CNQX inhibit neurofilament degradation and enhance neuronal survival in kainic acid-treated hippocampal slice cultures.
Journal: The European journal of neuroscience 20060501
Title: Developmental changes in NMDA neurotoxicity reflect developmental changes in subunit composition of NMDA receptors.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20060315
Title: Endoplasmic reticulum Ca2+ depletion induces endothelial cell apoptosis independently of caspase-12.
Journal: Cardiovascular research 20060301
Title: Calpain inhibitor MDL28170 modulates Abeta formation by inhibiting the formation of intermediate Abeta46 and protecting Abeta from degradation.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20060201
Title: Calpain inhibitor MDL 28170 protects hypoxic-ischemic brain injury in neonatal rats by inhibition of both apoptosis and necrosis.
Journal: Brain research 20050310
Title: Calpain inhibitor inhibits p35-p25-Cdk5 activation, decreases tau hyperphosphorylation, and improves neurological function after spinal cord hemisection in rats.
Journal: Journal of neuropathology and experimental neurology 20050101
Title: Ischemic preconditioning attenuates calpain-mediated degradation of structural proteins through a protein kinase A-dependent mechanism.
Journal: Cardiovascular research 20041001
Title: Epimerization study of the L,L- and L,D-diastereoisomers of the calpain inhibitor MDL 28170 by capillary electrophoresis.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20040925
Title: Both N-methyl-D-aspartate (NMDA) and non-NMDA receptors mediate glutamate-induced cleavage of the cyclin-dependent kinase 5 (cdk5) activator p35 in cultured rat hippocampal neurons.
Journal: Neuroscience letters 20040923
Title: The calpain inhibitor MDL 28170 prevents inflammation-induced neurofilament light chain breakdown in the spinal cord and reduces thermal hyperalgesia.
Journal: Pain 20040701
Title: Inhibition of severe acute respiratory syndrome-associated coronavirus (SARSCoV) by calpain inhibitors and beta-D-N4-hydroxycytidine.
Journal: Antiviral chemistry & chemotherapy 20040101
Title: Effects of fimbria-fornix transection on calpain and choline acetyl transferase activities in the septohippocampal pathway.
Journal: Neuroscience 20040101
Title: Protective effect of MDL28170 against thioacetamide-induced acute liver failure in mice.
Journal: Journal of biomedical science 20040101
Title: Calpain released from dying hepatocytes mediates progression of acute liver injury induced by model hepatotoxicants.
Journal: Toxicology and applied pharmacology 20030915
Title: Inhibition of calpains prevents neuronal and behavioral deficits in an MPTP mouse model of Parkinson's disease.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20030515
Title: A 48-hour exposure of pancreatic islets to calpain inhibitors impairs mitochondrial fuel metabolism and the exocytosis of insulin.
Journal: Metabolism: clinical and experimental 20030501
Title: Preinjury administration of the calpain inhibitor MDL-28170 attenuates traumatically induced axonal injury.
Journal: Journal of neurotrauma 20030301
Title: Lysophosphatidylcholine inhibits endothelial cell migration by increasing intracellular calcium and activating calpain.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20030201
Title: beta-Amyloid (1-40)-induced apoptosis of cultured cortical neurones involves calpain-mediated cleavage of poly-ADP-ribose polymerase.
Journal: Neurobiology of aging 20030101
Title: Evaluation of conditions for calpain inhibition in the rat spinal cord: effective postinjury inhibition with intraspinal MDL28170 microinjection.
Journal: Journal of neurotrauma 20030101
Title: Cleavage of the cyclin-dependent kinase 5 activator p35 to p25 does not induce tau hyperphosphorylation.
Journal: Biochemical and biophysical research communications 20021115
Title: Selective release of calpain produced alphalI-spectrin (alpha-fodrin) breakdown products by acute neuronal cell death.
Journal: Biological chemistry 20020501
Title: Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.
Journal: The Journal of biological chemistry 20020419
Title: In vitro isolation and identification of human immunodeficiency virus (HIV) variants with reduced sensitivity to C-2 symmetrical inhibitors of HIV type 1 protease.
Journal: Proceedings of the National Academy of Sciences of the United States of America 19930815
Title: Peptide aldehydes as inhibitors of HIV protease.
Journal: FEBS letters 19930322
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