[1]Arzneimittel-Forschung/DrugResearch,1980,vol.30,#116,p.2045-2053
[1]JournalofMedicinalChemistry,2017,vol.60,#2,p.681-694
[2]Patent:WO2009/105509,2009,A1,.Locationinpatent:Page/Pagecolumn36-37
[3]JournalofPharmaceuticalSciences,1980,vol.69,#1,p.92-93
[4]Patent:WO2008/104994,2008,A2,.Locationinpatent:Page/Pagecolumn32-33
[5]Patent:US2009/197959,2009,A1,.Locationinpatent:Page/Pagecolumn18
[1]Patent:CN105503564,2016,A,.Locationinpatent:Paragraph0005;0013;0014
[1]Synthesis,2004,#12,p.1959-1962
[2]JournalofMedicinalChemistry,1994,vol.37,#11,p.1712-1719
[3]JournaloftheChineseChemicalSociety,2007,vol.54,#3,p.575-578
[4]JournaloftheAmericanChemicalSociety,2013,vol.135,#20,p.7567-7571
[1]SpectrochimicaActa-PartA:MolecularandBiomolecularSpectroscopy,2008,vol.70,#5,p.1231-1237
[1]IndianJournalofChemistry-SectionBOrganicandMedicinalChemistry,1986,vol.25,p.566-568
[1]EuropeanJournalofMedicinalChemistry,1985,vol.20,p.302-308
[1]IndianJournalofChemistry-SectionBOrganicandMedicinalChemistry,1994,vol.33,p.168-170
[2]CanadianJournalofChemistry,1989,vol.67,p.1472-1479
[1]JournalofMedicinalChemistry,1986,vol.29,p.1138-1152
[1]Arzneimittel-Forschung/DrugResearch,1980,vol.30,p.2045-2053
Title: Effects of clofibric acid alone and in combination with 17β-estradiol on mRNA abundance in primary hepatocytes isolated from rainbow trout.
Journal: Toxicology in vitro : an international journal published in association with BIBRA 20140901
Title: Tissue-specific 5' heterogeneity of PPARα transcripts and their differential regulation by leptin.
Journal: PloS one 20130101
Title: Transition metal modified and partially calcined inorganic-organic pillared clays for the adsorption of salicylic acid, clofibric acid, carbamazepine, and caffeine from water.
Journal: Journal of colloid and interface science 20121115
Title: The role of microbial adaptation and biodegradable dissolved organic carbon on the attenuation of trace organic chemicals during groundwater recharge.
Journal: The Science of the total environment 20121015
Title: Interactions of acidic pharmaceuticals with human serum albumin: insights into the molecular toxicity of emerging pollutants.
Journal: Amino acids 20121001
Title: Photochemical fate of a mixture of emerging pollutants in the presence of humic substances.
Journal: Water research 20121001
Title: Effects of effluent organic matter characteristics on the removal of bulk organic matter and selected pharmaceutically active compounds during managed aquifer recharge: Column study.
Journal: Journal of contaminant hydrology 20121001
Title: Impact of the auxin signaling inhibitor p-chlorophenoxyisobutyric acid on short-term Cd-induced hydrogen peroxide production and growth response in barley root tip.
Journal: Journal of plant physiology 20120915
Title: Photocatalytic decomposition of crotamiton over aqueous TiO(2) suspensions: determination of intermediates and the reaction pathway.
Journal: Chemosphere 20120901
Title: Hormonal and chemical regulation of paraoxonases in mice.
Journal: The Journal of pharmacology and experimental therapeutics 20120901
Title: Assessment of possible carcinogenicity of oxyfluorfen to humans using mode of action analysis of rodent liver effects.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20120801
Title: Evaluation of aquatic plants for removing polar microcontaminants: a microcosm experiment.
Journal: Chemosphere 20120801
Title: Batch versus continuous feeding strategies for pharmaceutical removal by subsurface flow constructed wetland.
Journal: Environmental pollution (Barking, Essex : 1987) 20120801
Title: Distribution and temporal evolution of pharmaceutically active compounds alongside sewage sludge treatment. Risk assessment of sludge application onto soils.
Journal: Journal of environmental management 20120715
Title: Effects of pharmaceuticals on the expression of genes involved in detoxification in a carp primary hepatocyte model.
Journal: Environmental science & technology 20120605
Title: Solar regeneration of powdered activated carbon impregnated with visible-light responsive photocatalyst: factors affecting performances and predictive model.
Journal: Water research 20120601
Title: Additive effects of clofibric acid and pyruvate dehydrogenase kinase isoenzyme 4 (PDK4) deficiency on hepatic steatosis in mice fed a high saturated fat diet.
Journal: The FEBS journal 20120501
Title: Pharmaceutical removal in tropical subsurface flow constructed wetlands at varying hydraulic loading rates.
Journal: Chemosphere 20120401
Title: The PPARα agonists fenofibrate and CP-778875 cause increased β-oxidation, leading to oxidative injury in skeletal and cardiac muscle in the rat.
Journal: Toxicologic pathology 20120401
Title: Adsorptive removal of naproxen and clofibric acid from water using metal-organic frameworks.
Journal: Journal of hazardous materials 20120330
Title: Suspended biofilm carrier and activated sludge removal of acidic pharmaceuticals.
Journal: Water research 20120315
Title: Uptake of organic emergent contaminants in spath and lettuce: an in vitro experiment.
Journal: Journal of agricultural and food chemistry 20120227
Title: Analysis of endocrine disrupting compounds, pharmaceuticals and personal care products in sewage sludge by gas chromatography-mass spectrometry.
Journal: Talanta 20120130
Title: Differential induction of stearoyl-CoA desaturase 1 and 2 genes by fibrates in the liver of rats.
Journal: Biological & pharmaceutical bulletin 20120101
Title: The effectiveness of sewage treatment processes to remove faecal pathogens and antibiotic residues.
Journal: Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering 20120101
Title: Malignant ovarian tumors with induced expression of carbonyl reductase show spontaneous regression.
Journal: Clinical Medicine Insights. Oncology 20120101
Title: Analysis of anti-inflammatory, analgesic, stimulant and antidepressant drugs in purified water from wastewater treatment plants using SPE-LC tandem mass spectrometry.
Journal: Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering 20120101
Title: PPARs: Interference with Warburg' Effect and Clinical Anticancer Trials.
Journal: PPAR research 20120101
Title: Impact of solid retention time and nitrification capacity on the ability of activated sludge to remove pharmaceuticals.
Journal: Environmental technology 20120101
Title: Removal of pharmaceuticals in biologically treated wastewater by chlorine dioxide or peracetic acid.
Journal: Environmental technology 20120101
Title: Induction of 1-acylglycerophosphocholine acyltransferase genes by fibrates in the liver of rats.
Journal: Biological & pharmaceutical bulletin 20120101
Title: Microextraction by packed sorbent for the analysis of pharmaceutical residues in environmental water samples by in situ derivatization-programmed temperature vaporizer-gas chromatography-mass spectrometry.
Journal: Journal of chromatography. A 20111230
Title: Adsorption of clofibric acid and ketoprofen onto powdered activated carbon: effect of natural organic matter.
Journal: Environmental technology 20111201
Title: Ecotoxicological impacts of clofibric acid and diclofenac in common carp (Cyprinus carpio) fingerlings: hematological, biochemical, ionoregulatory and enzymological responses.
Journal: Journal of hazardous materials 20111115
Title: Organically functionalized mesoporous SBA-15 as sorbents for removal of selected pharmaceuticals from water.
Journal: Journal of hazardous materials 20111015
Title: Can pharmaceuticals interfere with the synthesis of active androgens in male fish? An in vitro study.
Journal: Marine pollution bulletin 20111001
Title: Effects of clofibric acid on the biliary excretion of benoxaprofen glucuronide and taurine conjugate in rats.
Journal: Die Pharmazie 20111001
Title: Cork-based activated carbons as supported adsorbent materials for trace level analysis of ibuprofen and clofibric acid in environmental and biological matrices.
Journal: Journal of chromatography. A 20110916
Title: In situ aqueous derivatization and determination of non-steroidal anti-inflammatory drugs by salting-out-assisted liquid-liquid extraction and gas chromatography-mass spectrometry.
Journal: Journal of chromatography. A 20110916
Title: Benzothiazole-based N-(phenylsulfonyl)amides as a novel family of PPARα antagonists.
Journal: Bioorganic & medicinal chemistry letters 20110815
Title: Reactive tracer test to evaluate the fate of pharmaceuticals in rivers.
Journal: Environmental science & technology 20110801
Title: Fulvic acid affects proliferation and maturation phases in Abies cephalonica embryogenic cells.
Journal: Journal of plant physiology 20110715
Title: Monitoring of pharmaceutically active compounds on the Guadalquivir River basin (Spain): occurrence and risk assessment.
Journal: Journal of environmental monitoring : JEM 20110701
Title: UV and VUV photolysis vs. UV/H2O2 and VUV/H2O2, treatment for removal of clofibric acid from aqueous solution.
Journal: Environmental technology 20110701
Title: Simultaneous determination of 20 pharmacologically active substances in cow's milk, goat's milk, and human breast milk by gas chromatography-mass spectrometry.
Journal: Journal of agricultural and food chemistry 20110511
Title: Comparison of four extraction methods for the analysis of pharmaceuticals in wastewater.
Journal: Journal of chromatography. A 20110506
Title: Auxin: a major player in the shoot-to-root regulation of root Fe-stress physiological responses to Fe deficiency in cucumber plants.
Journal: Plant physiology and biochemistry : PPB 20110501
Title: Assessment of the occurrence and distribution of pharmaceuticals in a Mediterranean wetland (L'Albufera, Valencia, Spain) by LC-MS/MS.
Journal: Analytical and bioanalytical chemistry 20110501
Title: Nitrification activity and community structure of nitrite-oxidizing bacteria in the bioreactors operated with addition of pharmaceuticals.
Journal: Journal of hazardous materials 20110415
Title: Fate of organic micropollutants in the hyporheic zone of a eutrophic lowland stream: results of a preliminary field study.
Journal: The Science of the total environment 20110415
Title: Decrease of hepatic stellate cells in rats with enhanced sensitivity to clofibrate-induced hepatocarcinogenesis.
Journal: Cancer science 20110401
Title: Occurrence and behavior of non-steroidal anti-inflammatory drugs and lipid regulators in wastewater and urban river water of the Pearl River Delta, South China.
Journal: Journal of environmental monitoring : JEM 20110401
Title: Vibrational spectra and natural bond orbital analysis of the herbicidal molecule 2(4-chlorophenoxy)-2-methyl propionic acid.
Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20110201
Title: Toxicological evaluation of acyl glucuronides of nonsteroidal anti-inflammatory drugs using human embryonic kidney 293 cells stably expressing human UDP-glucuronosyltransferase and human hepatocytes.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20110101
Title: Clofibric acid increases the formation of oleic acid in endoplasmic reticulum of the liver of rats.
Journal: Journal of pharmacological sciences 20110101
Title: Transcription of DWARF4 plays a crucial role in auxin-regulated root elongation in addition to brassinosteroid homeostasis in Arabidopsis thaliana.
Journal: PloS one 20110101
Title: Exposure of the main italian river basin to pharmaceuticals.
Journal: Journal of toxicology 20110101
Title: Alert-QSAR. Implications for electrophilic theory of chemical carcinogenesis.
Journal: International journal of molecular sciences 20110101
Title: The value of repeating studies and multiple controls: replicated 28-day growth studies of rainbow trout exposed to clofibric acid.
Journal: Environmental toxicology and chemistry 20101201
Title: Triglycerides and gallstone formation.
Journal: Clinica chimica acta; international journal of clinical chemistry 20101111
Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.
Journal: Bioorganic & medicinal chemistry letters 20101101
Title: Human health risk assessment of pharmaceuticals in water: issues and challenges ahead.
Journal: International journal of environmental research and public health 20101101
Title: Identification of the UDP-glucuronosyltransferase responsible for bucolome N-glucuronide formation in rats.
Journal: Die Pharmazie 20101101
Title: Fibrates plus betaine: a winning combination?
Journal: The New Zealand medical journal 20101015
Title: Rapid resolution liquid chromatography-tandem mass spectrometry method for the determination of endocrine disrupting chemicals (EDCs), pharmaceuticals and personal care products (PPCPs) in wastewater irrigated soils.
Journal: Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes 20101001
Title: Case report. Hyperlipoproteinaemia(a): which is the optimal therapy? A case report.
Journal: Journal of clinical pharmacy and therapeutics 20101001
Title: Treating mixed hyperlipidemia and the atherogenic lipid phenotype for prevention of cardiovascular events.
Journal: The American journal of medicine 20101001
Title: Effects of fibrates on cardiovascular outcomes.
Journal: Lancet (London, England) 20100925
Title: Effects of fibrates on cardiovascular outcomes.
Journal: Lancet (London, England) 20100925
Title: Liverbeads: a practical and relevant in vitro model for gene induction investigations.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20100901
Title: Beyond statin therapy: a review of the management of residual risk in diabetes mellitus.
Journal: Journal of the Royal Society of Medicine 20100901
Title: Lipid-lowering agents and new onset diabetes mellitus.
Journal: Expert opinion on pharmacotherapy 20100801
Title: Management of hypertriglyceridemia in the diabetic patient.
Journal: Current diabetes reports 20100801
Title: PPARalpha: an emerging therapeutic target in diabetic microvascular damage.
Journal: Nature reviews. Endocrinology 20100801
Title: Assessment of plant-driven removal of emerging organic pollutants by duckweed.
Journal: Chemosphere 20100801
Title: Fibrates: no ACCORD on their use in the treatment of dyslipidaemia.
Journal: Current opinion in lipidology 20100801
Title: Physiological interactions of antiauxins with auxin in roots.
Journal: Journal of plant physiology 20100715
Title: Occurrence and risk assessment of acidic pharmaceuticals in the Yellow River, Hai River and Liao River of north China.
Journal: The Science of the total environment 20100715
Title: [On behalf and the extent of evidence].
Journal: Revue medicale suisse 20100609
Title: Multi-residue method for the analysis of pharmaceutical compounds in sewage sludge, compost and sediments by sonication-assisted extraction and LC determination.
Journal: Journal of separation science 20100601
Title: Fibrates consistently lower risk of cardiovascular events across high-risk groups.
Journal: Cardiovascular journal of Africa 20100601
Title: Occurrence and a screening-level risk assessment of human pharmaceuticals in the Pearl River system, South China.
Journal: Environmental toxicology and chemistry 20100601
Title: Effects of fibrates on cardiovascular outcomes: a systematic review and meta-analysis.
Journal: Lancet (London, England) 20100529
Title: Fibrates in CVD: a step towards personalised medicine.
Journal: Lancet (London, England) 20100529
Title: Fibrates in the prevention of cardiovascular disease in patients with type 2 diabetes mellitus--a pooled meta-analysis of randomized placebo-controlled clinical trials.
Journal: International journal of cardiology 20100528
Title: Conservative treatment of L-asparaginase-associated lipid abnormalities in children with acute lymphoblastic leukemia.
Journal: Pediatric blood & cancer 20100501
Title: Pharmacotherapy of mixed dyslipidemia in the metabolic syndrome.
Journal: Current clinical pharmacology 20100501
Title: The effect of structure and a secondary carbon source on the microbial degradation of chlorophenoxy acids.
Journal: Chemosphere 20100501
Title: Fibrates, glitazones, and peroxisome proliferator-activated receptors.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20100501
Title: Management of cardiovascular risk associated with insulin resistance, diabetes, and the metabolic syndrome.
Journal: Postgraduate medicine 20100501
Title: Determination of pharmaceuticals in soils and sediments by pressurized liquid extraction and liquid chromatography tandem mass spectrometry.
Journal: Journal of chromatography. A 20100416
Title: Investigating the mechanism of clofibric acid removal in Fe(0)/H2O systems.
Journal: Journal of hazardous materials 20100415
Title: Clofibric acid degradation in UV254/H2O2 process: effect of temperature.
Journal: Journal of hazardous materials 20100415
Title: Dynamics and attenuation of acidic pharmaceuticals along a river stretch.
Journal: Environmental science & technology 20100415
Title: [Global therapy of diabetic dyslipidemia: benefits and new therapeutic approaches].
Journal: Medicina clinica 20100403
Title: Removal of pharmaceuticals from water: using liquid-core microcapsules as a novel approach.
Journal: Water research 20100401
Title: Orthopaedic/radiology/pathology conference: Multiple nodular outgrowths in the hands and feet of a 60-year-old man.
Journal: Clinical orthopaedics and related research 20100201
Title: Bezafibrate induces myotoxicity in human rhabdomyosarcoma cells via peroxisome proliferator-activated receptor alpha signaling.
Journal: Toxicology in vitro : an international journal published in association with BIBRA 20100201
Title: Removal of pharmaceuticals in microcosm constructed wetlands using Typha spp. and LECA.
Journal: Bioresource technology 20100201
Title: [HDL and CETP in atherogenesis].
Journal: Deutsche medizinische Wochenschrift (1946) 20100201
Title: Fibrate/Statin initiation in warfarin users and gastrointestinal bleeding risk.
Journal: The American journal of medicine 20100201
Title: Ecotoxicity assessment of lipid regulators in water and biologically treated wastewater using three aquatic organisms.
Journal: Environmental science and pollution research international 20100101
Title: Application of the combination index (CI)-isobologram equation to study the toxicological interactions of lipid regulators in two aquatic bioluminescent organisms.
Journal: Water research 20100101
Title: Management of hypertriglyceridaemia caused by combination antiretroviral therapy in HIV-infected patients: role of omega-3 polyunsaturated fatty acids at different dosages, compared with fibrates.
Journal: International journal of STD & AIDS 20100101
Title: Oxidation of atenolol, propranolol, carbamazepine and clofibric acid by a biological Fenton-like system mediated by the white-rot fungus Trametes versicolor.
Journal: Water research 20100101
Title: Discussion by Reinhard Länge et al. on 'Degradation of the endocrine disrupting chemicals (EDCs) carbamazepine, clofibric acid, and iopromide by corona discharge over water' by Krause et al. [Chemosphere 75(2) (2009) 163-168].
Journal: Chemosphere 20100101
Title: Apolipoprotein B, diabetes and medical consensus.
Journal: Annals of clinical biochemistry 20100101
Title: Photocatalytic degradation of clofibric acid, carbamazepine and iomeprol using conglomerated TiO2 and activated carbon in aqueous suspension.
Journal: Water science and technology : a journal of the International Association on Water Pollution Research 20100101
Title: Antivascular therapy for epithelial ovarian cancer.
Journal: Journal of oncology 20100101
Title: Peroxisome proliferator-activated receptor alpha (PPARalpha) agonists induce constitutive androstane receptor (CAR) and cytochrome P450 2B in rat primary hepatocytes.
Journal: Drug metabolism and pharmacokinetics 20100101
Title: Liquid chromatography with post-column reagent addition of ammonia in methanol coupled to negative ion electrospray ionization tandem mass spectrometry for determination of phenoxyacid herbicides and their degradation products in surface water.
Journal: Analytical chemistry insights 20100101
Title: [Lipid therapy in patients with diabetes].
Journal: Wiener medizinische Wochenschrift (1946) 20100101
Title: PPARalpha: energy combustion, hypolipidemia, inflammation and cancer.
Journal: Nuclear receptor signaling 20100101
Title: Sex-different hepaticglycogen content and glucose output in rats.
Journal: BMC biochemistry 20100101
Title: Methods of chromatographic determination of medicines decreasing the level of cholesterol.
Journal: Acta poloniae pharmaceutica 20100101
Title: PRIC295, a Nuclear Receptor Coactivator, Identified from PPARα-Interacting Cofactor Complex.
Journal: PPAR research 20100101
Title: Peroxisome proliferator-activated receptor alpha target genes.
Journal: PPAR research 20100101
Title: Effects of the PPARα Agonist and Widely Used Antihyperlipidemic Drug Gemfibrozil on Hepatic Toxicity and Lipid Metabolism.
Journal: PPAR research 20100101
Title: Gene Expression Changes Induced by PPAR Gamma Agonists in Animal and Human Liver.
Journal: PPAR research 20100101
Title: Fate of selected pharmaceuticals and personal care products after secondary wastewater treatment processes in Taiwan.
Journal: Water science and technology : a journal of the International Association on Water Pollution Research 20100101
Title: Maternal influences on the transmission of leukocyte gene expression profiles in population samples from Brisbane, Australia.
Journal: PloS one 20100101
Title: Molecular Pharmacology of Kidney and Inner Ear CLC-K Chloride Channels.
Journal: Frontiers in pharmacology 20100101
Title: Glucose sensing neurons in the ventromedial hypothalamus.
Journal: Sensors (Basel, Switzerland) 20100101
Title: Identification of intermediates and assessment of ecotoxicity in the oxidation products generated during the ozonation of clofibric acid.
Journal: Journal of hazardous materials 20091230
Title: Effects of lipid-lowering pharmaceuticals bezafibrate and clofibric acid on lipid metabolism in fathead minnow (Pimephales promelas).
Journal: Environmental toxicology and chemistry 20091201
Title: Statins, fibrates, nicotinic acid, cholesterol absorption inhibitors, anion-exchange resins, omega-3 fatty acids: which drugs for which patients?
Journal: Fundamental & clinical pharmacology 20091201
Title: Functional role of neuroendocrine-specific protein-like 1 in membrane translocation of GLUT4.
Journal: Diabetes 20091201
Title: Combination therapy of statins and fibrates in the management of cardiovascular risk.
Journal: Current opinion in lipidology 20091201
Title: Novel targets that affect high-density lipoprotein metabolism: the next frontier.
Journal: The American journal of cardiology 20091116
Title: The characteristics of enriched nitrifier culture in the degradation of selected pharmaceutically active compounds.
Journal: Journal of hazardous materials 20091115
Title: Phenoxy herbicides and fibrates potently inhibit the human chemosensory receptor subunit T1R3.
Journal: Journal of medicinal chemistry 20091112
Title: Degradation and adsorption of selected pharmaceuticals and personal care products (PPCPs) in agricultural soils.
Journal: Chemosphere 20091101
Title: Lipid disorders.
Journal: JAAPA : official journal of the American Academy of Physician Assistants 20091101
Title: A reexamination of the PPAR-alpha activation mode of action as a basis for assessing human cancer risks of environmental contaminants.
Journal: Environmental health perspectives 20091101
Title: Application of dynamic liquid-phase microextraction and injection port derivatization combined with gas chromatography-mass spectrometry to the determination of acidic pharmaceutically active compounds in water samples.
Journal: Journal of chromatography. A 20091030
Title: Statins, fibrates and retinoic acid upregulate mitochondrial acylcarnitine carrier gene expression.
Journal: Biochemical and biophysical research communications 20091030
Title: New 2-aryloxy-3-phenyl-propanoic acids as peroxisome proliferator-activated receptors alpha/gamma dual agonists with improved potency and reduced adverse effects on skeletal muscle function.
Journal: Journal of medicinal chemistry 20091022
Title: Synthesis and biological evaluation of 2-heteroarylthioalkanoic acid analogues of clofibric acid as peroxisome proliferator-activated receptor alpha agonists.
Journal: Journal of medicinal chemistry 20091022
Title: Review article: nuclear receptors and liver disease--current understanding and new therapeutic implications.
Journal: Alimentary pharmacology & therapeutics 20091015
Title: Subacute exposure to N-ethyl perfluorooctanesulfonamidoethanol results in the formation of perfluorooctanesulfonate and alters superoxide dismutase activity in female rats.
Journal: Archives of toxicology 20091001
Title: Regulation of CYP4A expression by bezafibrate in primary culture of rat and human hepatocytes: interspecies difference and influence of N-acetylcysteine.
Journal: Toxicology in vitro : an international journal published in association with BIBRA 20091001
Title: Fibrates may cause an abnormal urinary betaine loss which is associated with elevations in plasma homocysteine.
Journal: Cardiovascular drugs and therapy 20091001
Title: Prevention of local lipotoxicity: a new renoprotective mechanism of peroxisome proliferator-activated receptor-alpha activation in hypertension and obesity?
Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20091001
Title: Effect of fibrates on lipid profiles and cardiovascular outcomes: a systematic review.
Journal: The American journal of medicine 20091001
Title: Calcium-induced calcium release in skeletal muscle.
Journal: Physiological reviews 20091001
Title: Peroxisome proliferators attenuate free arachidonic acid pool in the kidney through inducing lysophospholipid acyltransferases.
Journal: Journal of pharmacological sciences 20091001
Title: A clinical puzzle: fibrates and homocysteine elevation: editorial to: 'fibrates may cause an abnormal urinary betaine loss which is associated with elevations in plasma homocysteine' by M. Lever et al.
Journal: Cardiovascular drugs and therapy 20091001
Title: [Place of fibrates for the treatment of patients with atherogenic dyslipidemia].
Journal: Revue medicale de Liege 20091001
Title: Ozonation of clofibric acid catalyzed by titanium dioxide.
Journal: Journal of hazardous materials 20090930
Title: Adsorptive removal of selected pharmaceuticals by mesoporous silica SBA-15.
Journal: Journal of hazardous materials 20090915
Title: Probing the fibrate binding specificity of rat liver fatty acid binding protein.
Journal: Journal of medicinal chemistry 20090910
Title: Leachability of some emerging contaminants in reclaimed municipal wastewater-irrigated turf grass fields.
Journal: Environmental toxicology and chemistry 20090901
Title: Dyslipidemia and cardiovascular risk: the importance of early prevention.
Journal: QJM : monthly journal of the Association of Physicians 20090901
Title: Enhancing cardiovascular disease risk reduction: raising high-density lipoprotein levels.
Journal: Current opinion in cardiology 20090901
Title: Factors modulating fibrates response: therapeutic implications and alternative strategies.
Journal: Endocrine, metabolic & immune disorders drug targets 20090901
Title: Myopathy with statin-fibrate combination therapy: clinical considerations.
Journal: Nature reviews. Endocrinology 20090901
Title: Fibrate therapy and renal function.
Journal: Current atherosclerosis reports 20090901
Title: The obesity, metabolic syndrome, and type 2 diabetes mellitus pandemic: II. Therapeutic management of atherogenic dyslipidemia.
Journal: Journal of clinical hypertension (Greenwich, Conn.) 20090901
Title: Differential regulation of the human versus the mouse apolipoprotein AV gene by PPARalpha. Implications for the study of pharmaceutical modifiers of hypertriglyceridemia in mice.
Journal: Biochimica et biophysica acta 20090801
Title: Co-medications that modulate liver injury and repair influence clinical outcome of acetaminophen-associated liver injury.
Journal: Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 20090801
Title: Occurrence of selected pharmaceuticals in an agricultural landscape, western Lake Erie basin.
Journal: Water research 20090801
Title: Advances in the medical treatment of diabetic retinopathy.
Journal: Diabetes care 20090801
Title: Single and combined toxicity of pharmaceuticals and personal care products (PPCPs) on the rainbow trout liver cell line RTL-W1.
Journal: Aquatic toxicology (Amsterdam, Netherlands) 20090726
Title: [HDL-cholesterol: from risk factor to therapeutic target].
Journal: Medicina clinica 20090711
Title: Iatrogenic severe depression of high-density lipoprotein cholesterol.
Journal: Journal of clinical pharmacology 20090701
Title: Fibrates in the treatment of cardiovascular risk and atherogenic dyslipidaemia.
Journal: Current opinion in cardiology 20090701
Title: Lipid-lowering drugs are associated with delayed onset and slower course of Parkinson's disease.
Journal: Pharmacological research 20090701
Title: Effects of WY-14643 on peroxisomal enzyme activity and hormone secretion in immortalized human trophoblast cells.
Journal: Biological & pharmaceutical bulletin 20090701
Title: [Efficacy and safety of etofibrate in patients with non-proliferative diabetic retinopathy].
Journal: Klinische Monatsblatter fur Augenheilkunde 20090701
Title: Analysis of selected pharmaceutical compounds and endocrine disruptors in municipal wastewater using solid-phase microextraction and gas chromatography.
Journal: Water environment research : a research publication of the Water Environment Federation 20090701
Title: Opposing roles of peroxisome proliferator-activated receptor alpha and growth hormone in the regulation of CYP4A11 expression in a transgenic mouse model.
Journal: The Journal of biological chemistry 20090612
Title: Lipids, lipid modifying agents and cardiovascular risk: a review of the evidence.
Journal: Clinical endocrinology 20090601
Title: Niacin and fibrate use among patients with high triglycerides and low high-density lipoprotein cholesterol.
Journal: Current medical research and opinion 20090601
Title: Comment on 'Oxidative degradation of organic compounds using zero-valent iron in the presence of natural organic matter serving as an electron shuttle'.
Journal: Environmental science & technology 20090515
Title: Analysis of differential gene expression in colorectal cancer and stroma using fluorescence-activated cell sorting purification.
Journal: British journal of cancer 20090505
Title: Antiplatelet actions of statins and fibrates are mediated by PPARs.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20090501
Title: In vitro genotoxic assessment of xenobiotic diacylglycerols in an in vitro micronucleus assay.
Journal: Environmental and molecular mutagenesis 20090501
Title: Update on therapeutic strategies to increase adiponectin function and secretion in metabolic syndrome.
Journal: Diabetes, obesity & metabolism 20090501
Title: Statin islands and PPAR ligands in platelets.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20090501
Title: [Diabetic dyslipoproteinemia: beyond LDL].
Journal: Deutsche medizinische Wochenschrift (1946) 20090501
Title: Anatase vs. rutile efficiency on the photocatalytic degradation of clofibric acid under near UV to visible irradiation.
Journal: Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20090501
Title: Fibrates in the chemical action of daunorubicin.
Journal: Current cancer drug targets 20090501
Title: Degradation of the endocrine disrupting chemicals (EDCs) carbamazepine, clofibric acid, and iopromide by corona discharge over water.
Journal: Chemosphere 20090401
Title: Occurrence and removal of pharmaceuticals in a municipal sewage treatment system in the south of Sweden.
Journal: The Science of the total environment 20090401
Title: Water quality improvement in a full-scale tertiary constructed wetland: effects on conventional and specific organic contaminants.
Journal: The Science of the total environment 20090401
Title: Rosiglitazone aggravates nonalcoholic Fatty pancreatic disease in C57BL/6 mice fed high-fat and high-sucrose diet.
Journal: Pancreas 20090401
Title: Automated potentiometric titrations in KCl/water-saturated octanol: method for quantifying factors influencing ion-pair partitioning.
Journal: Analytical chemistry 20090401
Title: Interpreting clinical trials of diabetic dyslipidaemia: new insights.
Journal: Diabetes, obesity & metabolism 20090301
Title: Differential regulation of peroxisome proliferator-activated receptor (PPAR)-alpha1 and truncated PPARalpha2 as an adaptive response to fasting in the control of hepatic peroxisomal fatty acid beta-oxidation in the hibernating mammal.
Journal: Endocrinology 20090301
Title: Lipid management in the geriatric patient.
Journal: Endocrinology and metabolism clinics of North America 20090301
Title: Activation of PPARalpha and PPARgamma reduces triacylglycerol synthesis in rat hepatoma cells by reduction of nuclear SREBP-1.
Journal: European journal of pharmacology 20090301
Title: Switching fibrate to statin in type 2 diabetic patients: consequences on lipid profile.
Journal: European journal of internal medicine 20090301
Title: The use of lipid-lowering drug therapy in children and adolescents.
Journal: Current opinion in investigational drugs (London, England : 2000) 20090301
Title: Free-radical-induced oxidative and reductive degradation of fibrate pharmaceuticals: kinetic studies and degradation mechanisms.
Journal: The journal of physical chemistry. A 20090219
Title: Properties of an oral preparation containing a chitosan salt.
Journal: Molecules (Basel, Switzerland) 20090213
Title: Toxicity and removal efficiency of pharmaceutical metabolite clofibric acid by Typha spp.--potential use for phytoremediation?
Journal: Bioresource technology 20090201
Title: Ability of white-rot fungi to remove selected pharmaceuticals and identification of degradation products of ibuprofen by Trametes versicolor.
Journal: Chemosphere 20090201
Title: Triglycerides and cardiovascular events in ACS: the need for combined lipid-altering therapies.
Journal: Nature clinical practice. Cardiovascular medicine 20090201
Title: Hyperlipidaemia and cardiovascular disease: nonlipid-lowering effects of omega-3 fatty acids, statins and fibrates.
Journal: Current opinion in lipidology 20090201
Title: Fibrates: where are we now?
Journal: Therapeutic advances in cardiovascular disease 20090201
Title: On the road to better dyslipidemia outcomes.
Journal: The Nurse practitioner 20090201
Title: Ten-year all-cause mortality in presumably healthy subjects on lipid-lowering drugs (from the Prospective Epidemiological Study of Myocardial Infarction [PRIME] prospective cohort).
Journal: The American journal of cardiology 20090201
Title: Meta-analysis of the relationship between non-high-density lipoprotein cholesterol reduction and coronary heart disease risk.
Journal: Journal of the American College of Cardiology 20090127
Title: A new respirometric endpoint-based biosensor to assess the relative toxicity of chemicals on immobilized human cells.
Journal: Ecotoxicology and environmental safety 20090101
Title: Determination of phenolic endocrine disrupting chemicals and acidic pharmaceuticals in surface water of the Pearl Rivers in South China by gas chromatography-negative chemical ionization-mass spectrometry.
Journal: The Science of the total environment 20090101
Title: Is there evidence-based hypolipidemic treatment with clinical benefit beyond statins?
Journal: Angiology 20090101
Title: HIV-1 infection and the PPARγ-dependent control of adipose tissue physiology.
Journal: PPAR research 20090101
Title: The effects of medications used for the management of dyslipidemia on postprandial lipemia.
Journal: Current medicinal chemistry 20090101
Title: Anti-inflammatory effects of fibrates: an overview.
Journal: Current medicinal chemistry 20090101
Title: Fibrates and microvascular complications in diabetes--insight from the FIELD study.
Journal: Current pharmaceutical design 20090101
Title: Fibrates but not statins increase plasma selenium in dyslipidemic aged patients--the EVA study.
Journal: Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 20090101
Title: Thermodynamics of lipophilic drug binding to intestinal fatty acid binding protein and permeation across membranes.
Journal: Molecular pharmaceutics 20090101
Title: Impact of sample acquisition and linear amplification on gene expression profiling of lung adenocarcinoma: laser capture micro-dissection cell-sampling versus bulk tissue-sampling.
Journal: BMC medical genomics 20090101
Title: Etofibrate enhances 123I-LDL-binding in human liver.
Journal: Hellenic journal of nuclear medicine 20090101
Title: [Fibrate-induced deterioration of renal function].
Journal: Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20090101
Title: PPAR-γ agonists and their effects on IGF-I receptor signaling: Implications for cancer.
Journal: PPAR research 20090101
Title: Regulation of sulfotransferase and UDP-glucuronosyltransferase gene expression by the PPARs.
Journal: PPAR research 20090101
Title: Comparative analysis of gene regulation by the transcription factor PPARalpha between mouse and human.
Journal: PloS one 20090101
Title: Identifying patients with metabolic syndrome.
Journal: The Practitioner 20090101
Title: [Treatment of dyslipidemia in patients with metabolic syndrome and chronic kidney disease].
Journal: Vnitrni lekarstvi 20090101
Title: Thinking beyond low-density lipoprotein cholesterol: strategies to further reduce cardiovascular risk.
Journal: Vascular health and risk management 20090101
Title: Serum and erythrocyte membrane phospholipids fatty acid composition in hyperlipidemia: effects of dietary intervention and combined diet and fibrate therapy.
Journal: General physiology and biophysics 20090101
Title: Ciprofibrate increases cholesteryl ester transfer protein gene expression and the indirect reverse cholesterol transport to the liver.
Journal: Lipids in health and disease 20090101
Title: Photo-degradation of clofibric acid by ultraviolet light irradiation at 185 nm.
Journal: Water science and technology : a journal of the International Association on Water Pollution Research 20090101
Title: Prediction of pharmacological and xenobiotic responses to drugs based on time course gene expression profiles.
Journal: PloS one 20090101
Title: Combined bezafibrate and medroxyprogesterone acetate: potential novel therapy for acute myeloid leukaemia.
Journal: PloS one 20090101
Title: Crystal structure of the peroxisome proliferator-activated receptor gamma (PPARgamma) ligand binding domain complexed with a novel partial agonist: a new region of the hydrophobic pocket could be exploited for drug design.
Journal: Journal of medicinal chemistry 20081225
Title: A review of the current status of the management of mixed dyslipidemia associated with diabetes mellitus and metabolic syndrome.
Journal: The American journal of cardiology 20081222
Title: 2-Methyl-2-(4-nitro-phen-oxy)propanoic acid.
Journal: Acta crystallographica. Section E, Structure reports online 20081201
Title: Influence of pharmaceutical residues on the structure of activated sludge bacterial communities in wastewater treatment bioreactors.
Journal: Water research 20081101
Title: When high is low: raising low levels of high-density lipoprotein cholesterol.
Journal: Current cardiology reports 20081101
Title: The role of triglycerides in cardiovascular risk.
Journal: Current cardiology reports 20081101
Title: Targeting residual cardiovascular risk: raising high-density lipoprotein cholesterol levels.
Journal: Postgraduate medical journal 20081101
Title: Substituted tertiary phosphine Ru(II) organometallics: catalytic utility on the hydrolysis of etofibrate in pharmaceuticals.
Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20081001
Title: Behaviour and biomarkers of oxidative stress in Gambusia holbrooki after acute exposure to widely used pharmaceuticals and a detergent.
Journal: Ecotoxicology and environmental safety 20081001
Title: HDL therapy for cardiovascular diseases: the road to HDL mimetics.
Journal: Current atherosclerosis reports 20081001
Title: Selective determination of acidic pharmaceuticals in wastewater using molecularly imprinted solid-phase extraction.
Journal: Analytica chimica acta 20080926
Title: PPAR-alpha: therapeutic role in diabetes-related cardiovascular disease.
Journal: Diabetes, obesity & metabolism 20080901
Title: Fibrates and future PPARalpha agonists in the treatment of cardiovascular disease.
Journal: Nature clinical practice. Cardiovascular medicine 20080901
Title: CEPHEUS Trial.
Journal: Archives of cardiovascular diseases 20080901
Title: Assessment of lipid-lowering treatment in France--the CEPHEUS study.
Journal: Archives of cardiovascular diseases 20080901
Title: Simultaneous determination of pharmaceuticals, endocrine disrupting compounds and hormone in soils by gas chromatography-mass spectrometry.
Journal: Journal of chromatography. A 20080822
Title: Effects of fibrates, anti-inflammatory drugs and antidepressants in the fish hepatoma cell line PLHC-1: cytotoxicity and interactions with cytochrome P450 1A.
Journal: Toxicology in vitro : an international journal published in association with BIBRA 20080801
Title: Therapy and clinical trials: metabolic syndrome and cardiovascular risk management.
Journal: Current opinion in lipidology 20080801
Title: A case of rhabdomyolysis and thromboembolic event secondary to fibrate monotherapy.
Journal: Acta cardiologica 20080801
Title: [Clock genes regulate circadian rhythm of lipid metabolism and infarction].
Journal: [Rinsho ketsueki] The Japanese journal of clinical hematology 20080801
Title: Colchicine: serious interactions.
Journal: Prescrire international 20080801
Title: Simvastatin with or without ezetimibe in familial hypercholesterolemia.
Journal: The New England journal of medicine 20080731
Title: [New trends in lipidology: the increasing role of HDL-cholesterol].
Journal: Orvosi hetilap 20080727
Title: Treatment of hypercholesterolemia in patients with primary biliary cirrhosis might be more beneficial than indicated.
Journal: Swiss medical weekly 20080726
Title: [Effectiveness of cardiometabolic risk reduction in patients with type 1 diabetes mellitus].
Journal: Orvosi hetilap 20080706
Title: Species-specific kinetics and zonation of hepatic DNA synthesis induced by ligands of PPARalpha.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20080701
Title: Occurrence of steroid estrogens, endocrine-disrupting phenols, and acid pharmaceutical residues in urban riverine water of the Pearl River Delta, South China.
Journal: The Science of the total environment 20080701
Title: Bibliography. Current world literature. HDL cholesterol.
Journal: Current opinion in cardiology 20080701
Title: Managing dyslipidemia in chronic kidney disease.
Journal: Journal of the American College of Cardiology 20080624
Title: Efficacy of rosuvastatin (5 mg and 10 mg) twice a week in patients intolerant to daily statins.
Journal: The American journal of cardiology 20080615
Title: Role of the p50 subunit of NF-kappaB in vitamin E-induced changes in mice treated with the peroxisome proliferator, ciprofibrate.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20080601
Title: Administration of ciprofibrate to lactating mothers induces PPARalpha-signaling pathway in the liver and kidney of suckling rats.
Journal: Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20080601
Title: Targeting residual cardiovascular risk: raising high-density lipoprotein cholesterol levels.
Journal: Heart (British Cardiac Society) 20080601
Title: Using liquid chromatography-ion trap mass spectrometry to determine pharmaceutical residues in Taiwanese rivers and wastewaters.
Journal: Chemosphere 20080601
Title: Diabetic dyslipidemia: a practical guide to therapy.
Journal: The Journal of family practice 20080601
Title: Statin-fibrate combination therapy.
Journal: The American journal of cardiology 20080515
Title: Behaviour of pharmaceutical products and biodegradation intermediates in horizontal subsurface flow constructed wetland. A microcosm experiment.
Journal: The Science of the total environment 20080501
Title: Inhibiting wild-type and C299S mutant AKR1B10; a homologue of aldose reductase upregulated in cancers.
Journal: European journal of pharmacology 20080428
Title: Evidence to support aggressive management of high-density lipoprotein cholesterol: implications of recent imaging trials.
Journal: The American journal of cardiology 20080417
Title: Comprehensive lipid management versus aggressive low-density lipoprotein lowering to reduce cardiovascular risk.
Journal: The American journal of cardiology 20080417
Title: Nicotinic acid, alone and in combinations, for reduction of cardiovascular risk.
Journal: The American journal of cardiology 20080417
Title: Dual mechanisms for the fibrate-mediated repression of proprotein convertase subtilisin/kexin type 9.
Journal: The Journal of biological chemistry 20080411
Title: Differential effects of fibrates on the metabolic activation of 2-phenylpropionic acid in rats.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20080401
Title: Presence and some characteristics of peroxisomes in immortalized human trophoblast cells.
Journal: Biological & pharmaceutical bulletin 20080401
Title: Effects of modifying triglycerides and triglyceride-rich lipoproteins on cardiovascular outcomes.
Journal: Journal of cardiovascular pharmacology 20080401
Title: Cross-talk between statins and PPARalpha in cardiovascular diseases: clinical evidence and basic mechanisms.
Journal: Trends in cardiovascular medicine 20080401
Title: Belgian expert opinion: how to reduce the residual risk in atherogenic dyslipidaemic patients: place of fibrates.
Journal: Acta cardiologica 20080401
Title: [Dyslipidemia in visceral obesity: pathophysiological mechanisms, clinical implications and therapy].
Journal: Giornale italiano di cardiologia (2006) 20080401
Title: HDL-C in post-menopausal women: An important therapeutic target.
Journal: International journal of cardiology 20080314
Title: Stereospecific synthesis and bio-activity of novel beta(3)-adrenoceptor agonists and inverse agonists.
Journal: Bioorganic & medicinal chemistry 20080301
Title: Vascular and metabolic effects of treatment of combined hyperlipidemia: focus on statins and fibrates.
Journal: International journal of cardiology 20080227
Title: First-line therapies for lowering triglyceride levels.
Journal: American family physician 20080215
Title: Effects of pharmaceutically active compounds on a mixed microbial community originating from a municipal wastewater treatment plant.
Journal: Environmental science & technology 20080215
Title: Ciglitazone induces caspase-independent apoptosis via p38-dependent AIF nuclear translocation in renal epithelial cells.
Journal: Toxicology 20080203
Title: Organic micropollutant removal in a full-scale surface flow constructed wetland fed with secondary effluent.
Journal: Water research 20080201
Title: Individual and mixture effects of selected pharmaceuticals and personal care products on the marine phytoplankton species Dunaliella tertiolecta.
Journal: Archives of environmental contamination and toxicology 20080201
Title: The treatment of dyslipidemia--what's left in the pipeline?
Journal: ChemMedChem 20080201
Title: Quantitative analysis of auxin-regulated proteins from basal part of leaf sheaths in rice by two-dimensional difference gel electrophoresis.
Journal: Phytochemistry 20080201
Title: Multiple benign symmetric lipomatosis--a differential diagnosis of obesity: is there a rationale for fibrate treatment?
Journal: Obesity surgery 20080201
Title: Lipid levels and cardiovascular risk in elderly women: a general population study of the effects of hormonal treatment and lipid-lowering agents.
Journal: Climacteric : the journal of the International Menopause Society 20080201
Title: Drugs for lipids.
Journal: Treatment guidelines from the Medical Letter 20080201
Title: Management of mixed dyslipidemia in patients with or at risk for cardiovascular disease: a role for combination fibrate therapy.
Journal: Clinical therapeutics 20080201
Title: Synthesis of polymeric thiazolidinedione and fibrate conjugates.
Journal: Archives of pharmacal research 20080201
Title: Does the addition of fibrates to statin therapy have a favorable risk to benefit ratio?
Journal: Current atherosclerosis reports 20080201
Title: Is there a role for fibrates in the management of dyslipidemia in the metabolic syndrome?
Journal: Arteriosclerosis, thrombosis, and vascular biology 20080101
Title: A role for IAA in the infection of Arabidopsis thaliana by Orobanche aegyptiaca.
Journal: Annals of botany 20080101
Title: Peroxisome proliferator-activated receptor alpha agonists enhance cardiomyogenesis of mouse ES cells by utilization of a reactive oxygen species-dependent mechanism.
Journal: Stem cells (Dayton, Ohio) 20080101
Title: P-chlorophenoxyisobutyric acid impairs auxin response for gravity-regulated peg formation in cucumber (Cucumis sativus) seedlings.
Journal: Journal of plant research 20080101
Title: Tissue distribution, ontogeny, and regulation of aldehyde dehydrogenase (Aldh) enzymes mRNA by prototypical microsomal enzyme inducers in mice.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20080101
Title: Differential associations between lipid-lowering drugs, statins and fibrates, and venous thromboembolism: role of drug induced homocysteinemia?
Journal: Thrombosis research 20080101
Title: Chylomicronemia and the chylomicronemia syndrome: a practical approach to management.
Journal: The American journal of medicine 20080101
Title: Optimal management of combined dyslipidemia: what have we behind statins monotherapy?
Journal: Advances in cardiology 20080101
Title: Update on the treatment of diabetic retinopathy.
Journal: TheScientificWorldJournal 20080101
Title: Lipid-lowering therapy in patients with type 2 diabetes: the case for early intervention.
Journal: Diabetes/metabolism research and reviews 20080101
Title: Fibrate-associated adverse effects beyond muscle and liver toxicity.
Journal: Current pharmaceutical design 20080101
Title: Treatment of high-risk older persons with lipid-lowering drug therapy.
Journal: American journal of therapeutics 20080101
Title: Fibrate therapy: an update.
Journal: Cardiology in review 20080101
Title: Use of statins and the risk of Parkinson's disease: a retrospective case-control study in the UK.
Journal: Drug safety 20080101
Title: Pigment epithelium-derived factor is an angiogenesis and lipid regulator that activates peroxisome proliferator-activated receptor alpha.
Journal: Advances in experimental medicine and biology 20080101
Title: Plasma PCSK9 levels are significantly modified by statins and fibrates in humans.
Journal: Lipids in health and disease 20080101
Title: Ciprofibrate, clofibric acid and respective glycinate derivatives. Effects of a four-week treatment on male lean and obese Zucker rats.
Journal: Arzneimittel-Forschung 20080101
Title: The Role of PPAR Ligands in Controlling Growth-Related Gene Expression and their Interaction with Lipoperoxidation Products.
Journal: PPAR research 20080101
Title: Mitochondria, PPARs, and Cancer: Is Receptor-Independent Action of PPAR Agonists a Key?
Journal: PPAR research 20080101
Title: Role of peroxisome proliferator-activated receptor alpha in the control of cyclooxygenase 2 and vascular endothelial growth factor: involvement in tumor growth.
Journal: PPAR research 20080101
Title: Therapeutic effects of fibrates in postprandial lipemia.
Journal: American journal of cardiovascular drugs : drugs, devices, and other interventions 20080101
Title: [Raising HDL cholesterol: which is the best strategy?].
Journal: Revista da Associacao Medica Brasileira (1992) 20080101
Title: Removal of selected pharmaceuticals by chlorination, coagulation-sedimentation and powdered activated carbon treatment.
Journal: Water science and technology : a journal of the International Association on Water Pollution Research 20080101
Title: Non invasive in vivo investigation of hepatobiliary structure and function in STII medaka (Oryzias latipes): methodology and applications.
Journal: Comparative hepatology 20080101
Title: Statins but not fibrates improve the atherogenic to anti-atherogenic lipoprotein particle ratio: a randomized crossover study.
Journal: BMC clinical pharmacology 20080101
Title: Determination of etofibrate, fenofibrate, and atorvastatin in pharmaceutical preparations and plasma using differential pulse polarographic and square wave voltammetric techniques.
Journal: Journal of AOAC International 20080101
Title: The importance of recognizing and treating low levels of high-density lipoprotein cholesterol: a new era in atherosclerosis management.
Journal: Reviews in cardiovascular medicine 20080101
Title: 2-Methyl-2-(4-nitro-phenyl-sulfanyl)-propanoic acid.
Journal: Acta crystallographica. Section E, Structure reports online 20080101
Title: High-density lipoprotein metabolism: potential therapeutic targets.
Journal: The American journal of cardiology 20071203
Title: Liver X receptors (LXRs). Part I: structure, function, regulation of activity, and role in lipid metabolism.
Journal: Postepy higieny i medycyny doswiadczalnej (Online) 20071203
Title: Fibrate therapy: safety considerations.
Journal: Current opinion in lipidology 20071201
Title: Effects of medication on cardiovascular events in the Japanese coronary artery disease (JCAD) study.
Journal: Circulation journal : official journal of the Japanese Circulation Society 20071201
Title: A comparison of the effectiveness of lipid-lowering therapy between HIV- and non-HIV-infected subjects with hyperlipidaemia.
Journal: International journal of STD & AIDS 20071201
Title: Atherosclerosis in type 2 diabetes: a role for fibrate therapy?
Journal: Diabetes & vascular disease research 20071201
Title: Bridging the gap in treatment options for patients with hypertriglyceridemia.
Journal: The Journal of family practice 20071201
Title: Behavior of selected priority organic pollutants in horizontal subsurface flow constructed wetlands: a preliminary screening.
Journal: Chemosphere 20071101
Title: Evaluation of UV irradiation for photolytic and oxidative degradation of pharmaceutical compounds in water.
Journal: Water research 20071101
Title: High incidence of reduced plasma HDL cholesterol in diabetic patients treated with rosiglitazone and fibrate.
Journal: Pharmacoepidemiology and drug safety 20071101
Title: Resequencing genomic DNA of patients with severe hypertriglyceridemia (MIM 144650).
Journal: Arteriosclerosis, thrombosis, and vascular biology 20071101
Title: Genetic characterization of mutants resistant to the antiauxin p-chlorophenoxyisobutyric acid reveals that AAR3, a gene encoding a DCN1-like protein, regulates responses to the synthetic auxin 2,4-dichlorophenoxyacetic acid in Arabidopsis roots.
Journal: Plant physiology 20071101
Title: The role of fibrates in the prevention of cardiovascular disease--a pooled meta-analysis of long-term randomized placebo-controlled clinical trials.
Journal: American heart journal 20071101
Title: Measuring biomarkers to assess the therapeutic effects of PPAR agonists?
Journal: Pharmacogenomics 20071101
Title: [Adverse effects of lipid-lowering medications].
Journal: Nihon rinsho. Japanese journal of clinical medicine 20071028
Title: [Drug-induced myopathies].
Journal: Nihon rinsho. Japanese journal of clinical medicine 20071028
Title: Peroxisome proliferator-activated receptor alpha and gamma ligands inhibit the growth of human ovarian cancer.
Journal: Oncology reports 20071001
Title: Carboxylic acid drug-induced DNA nicking in HEK293 cells expressing human UDP-glucuronosyltransferases: role of acyl glucuronide metabolites and glycation pathways.
Journal: Chemical research in toxicology 20071001
Title: Efficacy and safety of pioglitazone in treatment of a patient with an atypical partial lipodystrophy syndrome.
Journal: Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 20071001
Title: FPIN's clinical inquiries. Best alternatives to statins for treating hyperlipidemia.
Journal: American family physician 20071001
Title: Atherosclerosis and cardiovascular risk reduction with PPAR agonists.
Journal: Current atherosclerosis reports 20071001
Title: Mitochondrial impairment by PPAR agonists and statins identified via immunocaptured OXPHOS complex activities and respiration.
Journal: Toxicology and applied pharmacology 20070915
Title: Treating hypertriglyceridemia.
Journal: CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20070911
Title: Treating hypertriglyceridemia.
Journal: CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20070911
Title: Treating hypertriglyceridemia.
Journal: CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20070911
Title: Is it time to stop treating dyslipidaemia with fibrates?
Journal: The New Zealand medical journal 20070907
Title: Clinical practice. Hypertriglyceridemia.
Journal: The New England journal of medicine 20070906
Title: The mode of action of thidiazuron: auxins, indoleamines, and ion channels in the regeneration of Echinacea purpurea L.
Journal: Plant cell reports 20070901
Title: Characterization of 1-aminocyclopropane-1-carboxylate (ACC) deaminase containing Methylobacterium oryzae and interactions with auxins and ACC regulation of ethylene in canola (Brassica campestris).
Journal: Planta 20070901
Title: Diethylnitrosamine initiation does not alter clofibric acid-induced hepatocarcinogenesis in the rat.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20070901
Title: Preliminary studies into the effects of the human pharmaceutical Clofibric acid on sperm parameters in adult Fathead minnow.
Journal: Aquatic toxicology (Amsterdam, Netherlands) 20070815
Title: Liquid chromatography-(tandem) mass spectrometry for the follow-up of the elimination of persistent pharmaceuticals during wastewater treatment applying biological wastewater treatment and advanced oxidation.
Journal: Journal of chromatography. A 20070810
Title: The acyl-CoA thioesterase I is regulated by PPARalpha and HNF4alpha via a distal response element in the promoter.
Journal: Journal of lipid research 20070801
Title: Influence of HDL-cholesterol-elevating drugs on the in vitro activity of the HDL receptor SR-BI.
Journal: Journal of lipid research 20070801
Title: CEC enantioseparations on chiral monolithic columns: a study of the stereoselective degradation of (R/S)-dichlorprop [2-(2,4-dichlorophenoxy)propionic acid] in soil.
Journal: Electrophoresis 20070801
Title: Statin and statin-fibrate use was significantly associated with increased myositis risk in a managed care population.
Journal: Journal of clinical epidemiology 20070801
Title: Strategies for reducing cardiovascular risk in patients with hypertriglyceridemia.
Journal: The Journal of family practice 20070801
Title: [Intervention for hypertriglyceridemia].
Journal: Nihon rinsho. Japanese journal of clinical medicine 20070728
Title: [Intervention study for elevating high density lipoprotein cholesterol level].
Journal: Nihon rinsho. Japanese journal of clinical medicine 20070728
Title: [Role of fibrate in cardiovascular disease prevention].
Journal: Nihon rinsho. Japanese journal of clinical medicine 20070728
Title: Selection of a support matrix for the removal of some phenoxyacetic compounds in constructed wetlands systems.
Journal: The Science of the total environment 20070715
Title: Mitochondria, ciglitazone and liver: a neglected interaction in biochemical pharmacology.
Journal: European journal of pharmacology 20070712
Title: Expression and characterization of cytochrome P450 2X1 in channel catfish (Ictalurus punctatus).
Journal: Biochimica et biophysica acta 20070701
Title: Effect of chrysin and natural coumarins on UGT1A1 and 1A6 activities in rat and human hepatocytes in primary culture.
Journal: Planta medica 20070701
Title: Analytical development for analysis of pharmaceuticals in water samples by SPE and GC-MS.
Journal: Analytical and bioanalytical chemistry 20070601
Title: [Metabolically designed treatments: from biochemistry to the vessel lining].
Journal: La Revue de medecine interne 20070601
Title: Elimination of selected acidic pharmaceuticals from municipal wastewater by an activated sludge system and membrane bioreactors.
Journal: Environmental science & technology 20070515
Title: Studies on the metabolism of tolmetin to the chemically reactive acyl-coenzyme A thioester intermediate in rats.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20070501
Title: Management of hypertriglyceridemia.
Journal: American family physician 20070501
Title: The clinical significance of the size of low-density-lipoproteins and the modulation of subclasses by fibrates.
Journal: Current medical research and opinion 20070501
Title: Determination of anti-inflammatory drugs and estrogens in water by HPLC with UV detection.
Journal: Journal of separation science 20070501
Title: Hypertriglyceridemia and cardiovascular risk reduction.
Journal: Clinical therapeutics 20070501
Title: Hypertriglyceridemia: its etiology, effects and treatment.
Journal: CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20070410
Title: P450 CYP2C epoxygenase and CYP4A omega-hydroxylase mediate ciprofibrate-induced PPARalpha-dependent peroxisomal proliferation.
Journal: Journal of lipid research 20070401
Title: Stearoyl-CoA desaturase activity is elevated by the suppression of its degradation by clofibric acid in the liver of rats.
Journal: Journal of pharmacological sciences 20070401
Title: The role of PPAR-alpha agonists in the prevention of CVD in diabetes.
Journal: Current diabetes reports 20070401
Title: Clofibric acid, a peroxisome proliferator-activated receptor alpha ligand, inhibits growth of human ovarian cancer.
Journal: Molecular cancer therapeutics 20070401
Title: [IV Brazilian Guideline for Dyslipidemia and Atherosclerosis prevention: Department of Atherosclerosis of Brazilian Society of Cardiology].
Journal: Arquivos brasileiros de cardiologia 20070401
Title: Aqueous in situ derivatization of carboxylic acids by an ionic carbodiimide and 2,2,2-trifluoroethylamine for electron-capture detection.
Journal: Journal of chromatography. A 20070323
Title: Expert commentary: the safety of fibrates in lipid-lowering therapy.
Journal: The American journal of cardiology 20070319
Title: Safety considerations with fibrate therapy.
Journal: The American journal of cardiology 20070319
Title: Statins and the risk of pneumonia: a population-based, nested case-control study.
Journal: Pharmacotherapy 20070301
Title: Fibrates: what have we learned in the past 40 years?
Journal: Pharmacotherapy 20070301
Title: Fibrates upregulate TRB3 in lymphocytes independent of PPAR alpha by augmenting CCAAT/enhancer-binding protein beta (C/EBP beta) expression.
Journal: Molecular immunology 20070201
Title: LC-MS analysis and environmental risk of lipid regulators.
Journal: Analytical and bioanalytical chemistry 20070201
Title: Analysis of pharmaceuticals in wastewater and removal using a membrane bioreactor.
Journal: Analytical and bioanalytical chemistry 20070201
Title: Removal of pharmaceutical residues in a pilot wastewater treatment plant.
Journal: Analytical and bioanalytical chemistry 20070201
Title: Ultrastructural effects of pharmaceuticals (carbamazepine, clofibric acid, metoprolol, diclofenac) in rainbow trout (Oncorhynchus mykiss) and common carp (Cyprinus carpio).
Journal: Analytical and bioanalytical chemistry 20070201
Title: Human pharmaceuticals, antioxidants, and plasticizers in wastewater treatment plant and water reclamation plant effluents.
Journal: Water environment research : a research publication of the Water Environment Federation 20070201
Title: High performance liquid chromatographic determination of etofibrate and its hydrolysis products.
Journal: Journal of pharmaceutical and biomedical analysis 20070104
Title: Simultaneous quantification of polycyclic aromatic hydrocarbons (PAHs), polychlorinated biphenyls (PCBs), and pharmaceuticals and personal care products (PPCPs) in Mississippi river water, in New Orleans, Louisiana, USA.
Journal: Chemosphere 20070101
Title: Degradation of clofibric acid in acidic aqueous medium by electro-Fenton and photoelectro-Fenton.
Journal: Chemosphere 20070101
Title: Paradoxical HDL-C reduction during rosiglitazone and fibrate treatment.
Journal: Diabetic medicine : a journal of the British Diabetic Association 20070101
Title: A light- and electron-microscope study of hepatocytes of rats fed different diets.
Journal: Comptes rendus biologies 20070101
Title: Dual PPAR alpha/gamma agonists: promises and pitfalls in type 2 diabetes.
Journal: American journal of therapeutics 20070101
Title: Management of dyslipidemia in the metabolic syndrome: recommendations of the Spanish HDL-Forum.
Journal: American journal of cardiovascular drugs : drugs, devices, and other interventions 20070101
Title: Advances in swine transcriptomics.
Journal: International journal of biological sciences 20070101
Title: Ciprofibrate treatment decreases non-high density lipoprotein cholesterol and triglycerides and increases high density lipoprotein cholesterol in patients with Frederickson type IV dyslipidemia phenotype.
Journal: American journal of therapeutics 20070101
Title: [Molecular pharmacology and medicinal chemistry of fibrate].
Journal: Pharmazie in unserer Zeit 20070101
Title: [Fibrate in lipid metabolism disorders].
Journal: Pharmazie in unserer Zeit 20070101
Title: Clofibrate treatment in pigs: effects on parameters critical with respect to peroxisome proliferator-induced hepatocarcinogenesis in rodents.
Journal: BMC pharmacology 20070101
Title: [Fibrates and markers of inflammation].
Journal: Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20070101
Title: [Influence of combined, hypolipemic therapy on lipids and non-lipid atherosclerosis risk factors].
Journal: Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20070101
Title: [Pleiotropic effects of fibric acid derivatives (Lipanthyl-200) among patients with metabolic syndrome].
Journal: Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology 20070101
Title: Dyslipidemia as a risk factor for erectile dysfunction.
Journal: Current medicinal chemistry 20070101
Title: Pharmacoenvironmentology--a component of pharmacovigilance.
Journal: Environmental health : a global access science source 20070101
Title: Effects of statins, fibrates, rosuvastatin, and ezetimibe beyond cholesterol: the modulation of LDL size and subclasses in high-risk patients.
Journal: Advances in therapy 20070101
Title: Lipid-modifying therapy and attainment of cholesterol goals in Hungary: the return on expenditure achieved for lipid therapy (REALITY) study.
Journal: Clinical drug investigation 20070101
Title: An investigation of the effects of lipid-lowering medications: genome-wide linkage analysis of lipids in the HyperGEN study.
Journal: BMC genetics 20070101
Title: [When should an association of lipid-lowering drugs be proposed in a patient failing to reach therapeutic targets under monotherapy? Guidelines of the New French Society of Atherosclerosis].
Journal: Archives des maladies du coeur et des vaisseaux 20070101
Title: Treatment of dyslipidemia to reduce cardiovascular risk in patients with multiple risk factors.
Journal: Clinical cornerstone 20070101
Title: Targeting high-density lipoprotein cholesterol in the management of cardiovascular disease.
Journal: The American heart hospital journal 20070101
Title: Effectiveness and tolerability of oral administration of low-dose salmon oil to HIV patients with HAART-associated dyslipidemia.
Journal: HIV clinical trials 20070101
Title: [Therapy of dyslipidemia in post-infarction: state of the art].
Journal: La Clinica terapeutica 20070101
Title: Activating effect of benzbromarone, a uricosuric drug, on peroxisome proliferator-activated receptors.
Journal: PPAR research 20070101
Title: [Analysis of dietary habits and dietary intake in hypertensive smokers].
Journal: Przeglad lekarski 20070101
Title: Type 2 diabetes mellitus is associated with multiple cardiometabolic risk factors.
Journal: Clinical cornerstone 20070101
Title: Hypertriglyceridemia and cardiovascular disease management.
Journal: Journal of the American Academy of Nurse Practitioners 20070101
Title: [Fibrate and its perspective as a drug for metabolic syndrome].
Journal: Nihon rinsho. Japanese journal of clinical medicine 20061228
Title: Aryloxoalcanoic compounds induce resistance to antibiotic therapy in urinary tract infection caused by Escherichia coli.
Journal: FEMS immunology and medical microbiology 20061201
Title: Regulation of hepatic cholesterol synthesis by a novel protein (SPF) that accelerates cholesterol biosynthesis.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20061201
Title: [Favorable effects of decreasing lipids in patients with diabetes mellitus].
Journal: Deutsche medizinische Wochenschrift (1946) 20061201
Title: Fibrates after the FIELD study: Some answers, more questions.
Journal: Diabetes & vascular disease research 20061201
Title: Management of hyperlipidemia with statins in the older patient.
Journal: Clinical interventions in aging 20061201
Title: [New indications and therapeutic objectives for dyslipidemia].
Journal: Atencion primaria 20061130
Title: 9-cis beta-carotene-rich powder of the alga Dunaliella bardawil increases plasma HDL-cholesterol in fibrate-treated patients.
Journal: Atherosclerosis 20061101
Title: Human UDP-glucuronosyltransferase (UGT)1A3 enzyme conjugates chenodeoxycholic acid in the liver.
Journal: Hepatology (Baltimore, Md.) 20061101
Title: 20-HETE and salt-sensitivity of blood pressure a novel emerging concept.
Journal: American journal of hypertension 20061101
Title: Activation of peroxisome proliferator-activated receptor-gamma (PPARgamma) induces cell death through MAPK-dependent mechanism in osteoblastic cells.
Journal: Toxicology and applied pharmacology 20060901
Title: Nucleophilic group transfer reactivity for fibric acid derived drug molecules.
Journal: Journal of pharmaceutical sciences 20060901
Title: Fibrate therapy in patients with metabolic syndrome and diabetes mellitus.
Journal: Current atherosclerosis reports 20060901
Title: A critical role for peroxisomal proliferator-activated receptor-alpha nuclear receptors in the development of cardiomyocyte degeneration and necrosis.
Journal: The American journal of pathology 20060901
Title: Seasonality effects on pharmaceuticals and s-triazine herbicides in wastewater effluent and surface water from the Canadian side of the upper Detroit River.
Journal: Environmental toxicology and chemistry 20060901
Title: The interference of pharmaceuticals with endogenous and xenobiotic metabolizing enzymes in carp liver: an in-vitro study.
Journal: Environmental science & technology 20060815
Title: Cloning, tissue expression, and regulation of beagle dog CYP4A genes.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20060801
Title: Fibric acid derivatives in cardiovascular disease prevention: results from the large clinical trials.
Journal: Current opinion in lipidology 20060801
Title: Decrease in triglyceride level by bezafibrate is related to reduction of recurrent coronary events: a Bezafibrate Infarction Prevention substudy.
Journal: Coronary artery disease 20060801
Title: Clofibrate treatment promotes branched-chain amino acid catabolism and decreases the phosphorylation state of mTOR, eIF4E-BP1, and S6K1 in rat liver.
Journal: Life sciences 20060717
Title: Effects of ciprofibrate on testicular and adrenal steroidogenic enzymes in the rat.
Journal: Reproductive toxicology (Elmsford, N.Y.) 20060701
Title: Trace-level determination of pharmaceutical residues by LC-MS/MS in natural and treated waters. A pilot-survey study.
Journal: Analytical and bioanalytical chemistry 20060701
Title: Peroxisome proliferator-activated receptors in vascular biology-molecular mechanisms and clinical implications.
Journal: Vascular pharmacology 20060701
Title: Dyslipidaemia, hypercoagulability and the metabolic syndrome.
Journal: Current vascular pharmacology 20060701
Title: Is it necessary to add fibrate to statin therapy in the management of dyslipidemia of metabolic syndrome?
Journal: International journal of cardiology 20060616
Title: N-3 fatty acid supplementation decreases plasma homocysteine in diabetic dyslipidemia treated with statin-fibrate combination.
Journal: The Journal of nutritional biochemistry 20060601
Title: Cytochrome P450 gene induction in rats ex vivo assessed by quantitative real-time reverse transcriptase-polymerase chain reaction (TaqMan).
Journal: Drug metabolism and disposition: the biological fate of chemicals 20060601
Title: Metabolomic study of cisplatin-induced nephrotoxicity.
Journal: Kidney international 20060601
Title: Ciprofibrate increases paraoxonase activity in patients with metabolic syndrome.
Journal: British journal of clinical pharmacology 20060601
Title: [Nuclear receptors PPARalpha].
Journal: Vnitrni lekarstvi 20060601
Title: PRIC320, a transcription coactivator, isolated from peroxisome proliferator-binding protein complex.
Journal: Biochemical and biophysical research communications 20060505
Title: Separation of fibrate-type antihyperlipidemic drugs by capillary electrophoresis and their quantitation in pharmaceuticals.
Journal: Journal of pharmaceutical and biomedical analysis 20060503
Title: Lipid-lowering drugs.
Journal: Cellular and molecular life sciences : CMLS 20060501
Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.
Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
Title: Apolipoproteins AI and B as therapeutic targets.
Journal: Journal of internal medicine 20060501
Title: Field of confusion: future prospects for fibrate therapy in cardiovascular disease.
Journal: Current atherosclerosis reports 20060501
Title: Bioactivation of carboxylic acid compounds by UDP-Glucuronosyltransferases to DNA-damaging intermediates: role of glycoxidation and oxidative stress in genotoxicity.
Journal: Chemical research in toxicology 20060501
Title: [Intensive cholesterol lowering therapy to reduce cardiovascular risk].
Journal: Revista medica de Chile 20060501
Title: Is atorvastatin superior to other statins? Analysis of the clinical trials with atorvastatin having cardiovascular endpoints.
Journal: Reviews on recent clinical trials 20060501
Title: Statin safety: a systematic review.
Journal: The American journal of cardiology 20060417
Title: [Diabetic dyslipoproteinemia].
Journal: MMW Fortschritte der Medizin 20060406
Title: HDL: the 'new' target of cardiovascular medicine.
Journal: International journal of cardiology 20060404
Title: Early diet-induced non-alcoholic steatohepatitis in APOE2 knock-in mice and its prevention by fibrates.
Journal: Journal of hepatology 20060401
Title: Fish oil increases bile acid synthesis in male patients with hypertriglyceridemia.
Journal: The Journal of nutrition 20060401
Title: [The fibrate-activated PPARalpha/p16INK4A pathway inhibits vascular smooth muscle cell proliferation and vascular occlusion].
Journal: Medecine sciences : M/S 20060401
Title: [Hyperlipidemia].
Journal: Nihon rinsho. Japanese journal of clinical medicine 20060401
Title: [Treatment of dyslipidemia: how and when to combine lipid lowering drugs].
Journal: Arquivos brasileiros de endocrinologia e metabologia 20060401
Title: Cardioprotective properties of fibrates: which fibrate, which patients, what mechanism?
Journal: Circulation 20060328
Title: [Treatment of dyslipidemia in clinical practice].
Journal: Orvosi hetilap 20060305
Title: The occurrence of selected pharmaceuticals in wastewater effluent and surface waters of the lower Tyne catchment.
Journal: The Science of the total environment 20060301
Title: Enantiomeric separation of some demethylated analogues of clofibric acid by capillary zone electrophoresis and nano-liquid chromatography.
Journal: Electrophoresis 20060301
Title: [Changes in serum lipids, plasma fibrinogen and other haemostatic parameters induced by ciprofibrate action in hyperlipidemic patients with and without coronary artery disease].
Journal: Investigacion clinica 20060301
Title: Fibrates in the prevention of cardiovascular disease in patients with type 2 diabetes mellitus: meta-analysis of randomised controlled trials.
Journal: Current medical research and opinion 20060301
Title: [Fibrates, nicotinic acid preparations and muscular pain].
Journal: Lakartidningen 20060301
Title: Is there evidence for the evidence-based guidelines for cardiovascular disease prevention in women?
Journal: Gender medicine 20060301
Title: Strategies for management and treatment of dyslipidemia in HIV/AIDS.
Journal: AIDS care 20060201
Title: Preliminary risk assessment of the lipid-regulating pharmaceutical clofibric acid, for three estuarine species.
Journal: Environmental research 20060201
Title: Management of hyperlipidemia: new LDL-C targets for persons at high-risk for cardiovascular events.
Journal: Medical science monitor : international medical journal of experimental and clinical research 20060201
Title: 'Anti-inflammatory' drugs and their effects on type 2 diabetes.
Journal: Diabetes technology & therapeutics 20060201
Title: Effects of widely used pharmaceuticals and a detergent on oxidative stress biomarkers of the crustacean Artemia parthenogenetica.
Journal: Chemosphere 20060101
Title: Anti-atherogenic properties of fibrates may be largely due to their anti-inflammatory effects.
Journal: Medical hypotheses 20060101
Title: Lipid testing and lipid-lowering therapy in hospitalized ischemic stroke and transient ischemic attack patients: results from a statewide stroke registry.
Journal: Stroke 20060101
Title: Assessment of compliance with lipid guidelines in an academic medical center.
Journal: The Annals of pharmacotherapy 20060101
Title: Statin/fibrate combination in patients with metabolic syndrome or diabetes: evaluating the risks of pharmacokinetic drug interactions.
Journal: Expert opinion on drug safety 20060101
Title: Low-density lipoprotein size and cardiovascular risk assessment.
Journal: QJM : monthly journal of the Association of Physicians 20060101
Title: Fibrates in combination with statins in the management of dyslipidemia.
Journal: Journal of clinical hypertension (Greenwich, Conn.) 20060101
Title: The metabolic syndrome--what is it and how should it be managed?
Journal: Journal of clinical hypertension (Greenwich, Conn.) 20060101
Title: Diabetes mellitus-associated atherosclerosis: mechanisms involved and potential for pharmacological invention.
Journal: American journal of cardiovascular drugs : drugs, devices, and other interventions 20060101
Title: Flow cytometric assessment of peroxisome proliferation from frozen liver of fibrate-treated monkeys.
Journal: International journal of toxicology 20060101
Title: Mode of action of fibrates in the regulation of triglyceride and HDL-cholesterol metabolism.
Journal: Drugs of today (Barcelona, Spain : 1998) 20060101
Title: Regulatory effects of synthetic liver X receptor- and peroxisome-proliferator activated receptor agonists on sterol transport pathways in polarized cerebrovascular endothelial cells.
Journal: The international journal of biochemistry & cell biology 20060101
Title: Biologically relevant effects of mRNA amplification on gene expression profiles.
Journal: BMC bioinformatics 20060101
Title: Potential of fibrates in the treatment of fatty acid oxidation disorders: revival of classical drugs?
Journal: Journal of inherited metabolic disease 20060101
Title: 2-{3-[2-(4-chlorophenyl)ethoxy]phenylthio}-2-methylpropanoic acid: a fibrate-like compound with hypolipidemic and antidiabetic activity.
Journal: ChemMedChem 20060101
Title: Gene expression profiles in rat liver slices exposed to hepatocarcinogenic enzyme inducers, peroxisome proliferators, and 17alpha-ethinylestradiol.
Journal: International journal of toxicology 20060101
Title: Effect of clofibric acid on desmin and vimentin contents in rat myocardiocytes.
Journal: International journal of toxicology 20060101
Title: Atherogenic dyslipidemia in metabolic syndrome and type 2 diabetes: therapeutic options beyond statins.
Journal: Cardiovascular diabetology 20060101
Title: [Clinical trials of statins and fibrates --a meta-analysis].
Journal: Medicinski pregled 20060101
Title: Comparison of effects of fibrates in patients with hypertriglyceridemia.
Journal: Advances in therapy 20060101
Title: [Cardiovascular risk and possibilities of lowering it in patients with metabolic syndrome and type II diabetes mellitus. The role of fibrates].
Journal: Kardiologiia 20060101
Title: Examination of Ligand-Dependent Coactivator Recruitment by Peroxisome Proliferator-Activated Receptor-alpha (PPARalpha).
Journal: PPAR research 20060101
Title: Cardiovascular disease: strategies for risk assessment and modification.
Journal: The Journal of cardiovascular nursing 20060101
Title: Prolonged statin administration does not act on the cell-mediated immunity of HIV-infected dyslipidemic patients treated with a steady and effective highly active antiretroviral therapy. A two-year prospective study of statin versus fibrate administration.
Journal: Journal of biological regulators and homeostatic agents 20060101
Title: [Synthesis and physico-chemical characterisation of some new derivatives of rutoside and clofibric acid].
Journal: Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi 20060101
Title: [Continuing care of patients with cardiovascular risk in general practice: patients with dyslipidemia and their care].
Journal: Orvosi hetilap 20051225
Title: [New studies of high dosage statins and fibrates. How is lipid lowering therapy changing? (interview by Dr. med. Dirk Einecke)].
Journal: MMW Fortschritte der Medizin 20051208
Title: Ciprofibrate stimulates the gastrin-producing cell by acting luminally on antral PPAR-alpha.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20051201
Title: Role for fibrate therapy in diabetes: evidence before FIELD.
Journal: Current opinion in lipidology 20051201
Title: Fibrate prevents cisplatin-induced proximal tubule cell death.
Journal: Kidney international 20051201
Title: Household disposal of pharmaceuticals as a pathway for aquatic contamination in the United kingdom.
Journal: Environmental health perspectives 20051201
Title: Optimal lipid modification: the rationale for combination therapy.
Journal: Vascular health and risk management 20051201
Title: Fibrates inhibit aldose reductase activity in the forward and reverse reactions.
Journal: Biochemical pharmacology 20051125
Title: Phytol directly activates peroxisome proliferator-activated receptor alpha (PPARalpha) and regulates gene expression involved in lipid metabolism in PPARalpha-expressing HepG2 hepatocytes.
Journal: Biochemical and biophysical research communications 20051118
Title: Modifying plasma low-density lipoprotein and high-density lipoprotein cholesterol: what combinations are available in the future?
Journal: The American journal of cardiology 20051107
Title: Pharmacokinetic interactions between statins and fibrates.
Journal: The American journal of cardiology 20051107
Title: Severe rhabdomyolysis during a hypersensitivity reaction to abacavir in a patient treated with ciprofibrate.
Journal: AIDS (London, England) 20051104
Title: Gene expression profiling of the PPAR-alpha agonist ciprofibrate in the cynomolgus monkey liver.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20051101
Title: Beneficial vascular and metabolic effects of peroxisome proliferator-activated receptor-alpha activators.
Journal: Hypertension (Dallas, Tex. : 1979) 20051101
Title: Hypertriglyceridemia-why, when and how should it be treated?
Journal: Zeitschrift fur Kardiologie 20051101
Title: Differential associations of statin and fibrate treatment with carotid arterial remodeling.
Journal: American journal of hypertension 20051101
Title: Therapeutical effects of PPAR agonists assessed by biomarker modulation.
Journal: Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 20051101
Title: Orthogonal array designs for the optimization of liquid-liquid-liquid microextraction of nonsteroidal anti-inflammatory drugs combined with high-performance liquid chromatography-ultraviolet detection.
Journal: Journal of chromatography. A 20051028
Title: Statins and fibrates for preventing melanoma.
Journal: The Cochrane database of systematic reviews 20051019
Title: Fibrates and coronary risk reduction.
Journal: Atherosclerosis 20051001
Title: Effects of pharmaceuticals on Daphnia survival, growth, and reproduction.
Journal: Chemosphere 20051001
Title: High-density lipoprotein cholesterol: ready for prime time?
Journal: Singapore medical journal 20051001
Title: Patients with low levels of high-density lipoprotein cholesterol: to treat or not to treat?
Journal: Singapore medical journal 20051001
Title: Lipoprotein-associated phospholipase A2 as a biomarker for coronary disease and stroke.
Journal: Nature clinical practice. Cardiovascular medicine 20051001
Title: [Drug combinations: statins and fibrates].
Journal: Arquivos brasileiros de cardiologia 20051001
Title: Clinical practice. Low HDL cholesterol levels.
Journal: The New England journal of medicine 20050922
Title: Synthesis and antiplatelet activity of thioaryloxyacids analogues of clofibric acid.
Journal: European journal of medicinal chemistry 20050901
Title: Pleiotropic effects of fibrates.
Journal: Current atherosclerosis reports 20050901
Title: Monocyte release of tumor necrosis factor-alpha and interleukin-1beta in primary type IIa and IIb dyslipidemic patients treated with statins or fibrates.
Journal: Journal of cardiovascular pharmacology 20050901
Title: Differential antiatherogenic effects of PPARalpha versus PPARgamma agonists: should we be surprised?
Journal: Arteriosclerosis, thrombosis, and vascular biology 20050901
Title: Current perspective. Diabetic vascular disease: from endothelial dysfunction to atherosclerosis.
Journal: Italian heart journal : official journal of the Italian Federation of Cardiology 20050901
Title: Synthesis, biological evaluation, and molecular modeling investigation of new chiral fibrates with PPARalpha and PPARgamma agonist activity.
Journal: Journal of medicinal chemistry 20050825
Title: Management of dyslipidemia in patients with complicated metabolic syndrome.
Journal: The American journal of cardiology 20050822
Title: Anti-inflammatory effect of fibrate protects from cisplatin-induced ARF.
Journal: American journal of physiology. Renal physiology 20050801
Title: Modulation of hepatic canalicular or basolateral transport proteins alters hepatobiliary disposition of a model organic anion in the isolated perfused rat liver.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20050801
Title: Fate and mobility of pharmaceuticals in solid matrices.
Journal: Chemosphere 20050801
Title: Therapeutic roles of peroxisome proliferator-activated receptor agonists.
Journal: Diabetes 20050801
Title: Demystifying triglycerides: a practical approach for the clinician.
Journal: Cleveland Clinic journal of medicine 20050801
Title: Electrochemical determination of pharmaceuticals in spiked water samples.
Journal: Journal of hazardous materials 20050715
Title: Environmental fate of pharmaceuticals in water/sediment systems.
Journal: Environmental science & technology 20050715
Title: Behavior of selected pharmaceuticals in subsurface flow constructed wetlands: a pilot-scale study.
Journal: Environmental science & technology 20050715
Title: Expression and induction potential of cytochromes P450 in human cryopreserved hepatocytes.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20050701
Title: Adiponectin receptor gene expression in human skeletal muscle cells is not regulated by fibrates and thiazolidinediones.
Journal: International journal of obesity (2005) 20050701
Title: Acute toxicity of widely used pharmaceuticals in aquatic species: Gambusia holbrooki, Artemia parthenogenetica and Tetraselmis chuii.
Journal: Ecotoxicology and environmental safety 20050701
Title: Pharmacologic augmentation of high-density lipoproteins: mechanisms of currently available and emerging therapies.
Journal: Current opinion in cardiology 20050701
Title: Effects of fibrates on human organic anion-transporting polypeptide 1B1-, multidrug resistance protein 2- and P-glycoprotein-mediated transport.
Journal: Xenobiotica; the fate of foreign compounds in biological systems 20050701
Title: Induction of overlapping genes by fasting and a peroxisome proliferator in pigs: evidence of functional PPARalpha in nonproliferating species.
Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20050601
Title: Hepatic beta-oxidation and carnitine palmitoyltransferase I in neonatal pigs after dietary treatments of clofibric acid, isoproterenol, and medium-chain triglycerides.
Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20050601
Title: Induction of pancreatic acinar cell proliferation by thyroid hormone.
Journal: The Journal of endocrinology 20050601
Title: Expression of cytochrome P450 enzymes in hepatic organoid reconstructed by rat small hepatocytes.
Journal: Journal of gastroenterology and hepatology 20050601
Title: [Significance of HDL cholesterol increase for the risk reduction. Methods of intervention. recommendations of experts].
Journal: Kardiologia polska 20050601
Title: [Treatment of lipid disorders in metabolic syndrome and type 2 diabetes. The place for fibrates].
Journal: Kardiologia polska 20050601
Title: [Influence of ACE inhibitors and fibrates on endothelial function].
Journal: Kardiologia polska 20050601
Title: [Pleiotropic action of ACE-I and fibrates].
Journal: Kardiologia polska 20050601
Title: [Combination pharmacotherapy therapy in the management of atherogenic dyslipidemia].
Journal: Kardiologia polska 20050601
Title: PPAR-alpha activators suppress STAT1 inflammatory signaling in lipopolysaccharide-activated rat glia.
Journal: Neuroreport 20050531
Title: Differences in cell proliferation in rodent and human hepatic derived cell lines exposed to ciprofibrate.
Journal: Cancer letters 20050526
Title: The benefit of fibrates in the treatment of 'bad HDL-C responders to statins'.
Journal: International journal of cardiology 20050525
Title: APOE genotype, cholesterol level, lipid-lowering treatment, and dementia: the Three-City Study.
Journal: Neurology 20050510
Title: Occurrence of several acidic drugs in sewage treatment plants in Switzerland and risk assessment.
Journal: Water research 20050501
Title: The potential use of PPARalpha agonists as immunosuppressive agents.
Journal: Current opinion in investigational drugs (London, England : 2000) 20050501
Title: Regulation of palmitoyl-CoA chain elongation by clofibric acid in the liver of Zucker fa/fa rats.
Journal: Lipids 20050501
Title: Effect of different antilipidemic agents and diets on mortality: a systematic review.
Journal: Archives of internal medicine 20050411
Title: Regulation of human hepatic hydroxysteroid sulfotransferase gene expression by the peroxisome proliferator-activated receptor alpha transcription factor.
Journal: Molecular pharmacology 20050401
Title: Characterization of an acute molecular marker of nongenotoxic rodent hepatocarcinogenesis by gene expression profiling in a long term clofibric acid study.
Journal: Chemical research in toxicology 20050401
Title: Automorphosis of etiolated pea seedlings in space is simulated by a three-dimensional clinostat and the application of inhibitors of auxin polar transport.
Journal: Physiologia plantarum 20050401
Title: Rhabdomyolysis and lipid-lowering drugs.
Journal: JAMA 20050323
Title: Operational options to reduce matrix effects in liquid chromatography-electrospray ionization-mass spectrometry analysis of aqueous environmental samples.
Journal: Journal of chromatography. A 20050304
Title: Effect of lipid-lowering drug therapy on small-dense low-density lipoprotein.
Journal: The Annals of pharmacotherapy 20050301
Title: Drugs for lipids.
Journal: Treatment guidelines from the Medical Letter 20050301
Title: Cross-flow microfiltration with periodical back-washing for photocatalytic degradation of pharmaceutical and diagnostic residues-evaluation of the long-term stability of the photocatalytic activity of TiO2.
Journal: Water research 20050301
Title: Management of dyslipidemia in women in the post-hormone therapy era.
Journal: Journal of general internal medicine 20050301
Title: Beyond the statins: new therapeutic perspectives in cardiovascular disease prevention.
Journal: Cardiovascular drugs and therapy 20050301
Title: Help for your cholesterol when statins won't do. If you are one of the many, but also one of the few..
Journal: Harvard men's health watch 20050301
Title: Determination of pharmaceutical residues in waters by solid-phase extraction and large-volume on-line derivatization with gas chromatography-mass spectrometry.
Journal: Journal of chromatography. A 20050218
Title: Pretranslational upregulation of microsomal CYP4A in rat liver by intake of a high-sucrose, lipid-devoid diet containing orotic acid.
Journal: Biochemical pharmacology 20050215
Title: [Myopathies under therapy with lipid-lowering agents].
Journal: Der Nervenarzt 20050201
Title: Hypolipidemic drugs affect monocyte IL-1beta gene expression and release in patients with IIa and IIb dyslipidemia.
Journal: Journal of cardiovascular pharmacology 20050201
Title: Rationale for combination therapy with statin drugs in the treatment of dyslipidemia.
Journal: Current atherosclerosis reports 20050201
Title: [Dyslipidemia management in patients with impaired glucose tolerance].
Journal: Nihon rinsho. Japanese journal of clinical medicine 20050201
Title: Have we forgotten the pivotal role of high-density lipoprotein cholesterol in atherosclerosis prevention?
Journal: Current medical research and opinion 20050201
Title: Dissociation of branched-chain alpha-keto acid dehydrogenase kinase (BDK) from branched-chain alpha-keto acid dehydrogenase complex (BCKDC) by BDK inhibitors.
Journal: Journal of nutritional science and vitaminology 20050201
Title: Efficacy and safety of high-density lipoprotein cholesterol-increasing compounds: a meta-analysis of randomized controlled trials.
Journal: Journal of the American College of Cardiology 20050118
Title: Photocatalytic degradation of carbamazepine, clofibric acid and iomeprol with P25 and Hombikat UV100 in the presence of natural organic matter (NOM) and other organic water constituents.
Journal: Water research 20050101
Title: Management of diabetic dyslipidemia: need for reappraisal of the goals.
Journal: American journal of cardiovascular drugs : drugs, devices, and other interventions 20050101
Title: Comparative effects of fibrates on drug metabolizing enzymes in human hepatocytes.
Journal: Pharmaceutical research 20050101
Title: [Cardiovascular system drugs. 9/12. Antilipemics--II. Fibrates and colestyramine].
Journal: Soins; la revue de reference infirmiere 20050101
Title: AhR and PPARalpha: antagonistic effects on CYP2B and CYP3A, and additive inhibitory effects on CYP2C11.
Journal: Xenobiotica; the fate of foreign compounds in biological systems 20050101
Title: Diabetic dyslipidaemia: insights for optimizing patient management.
Journal: Current medical research and opinion 20050101
Title: Outcome studies in type 2 diabetes.
Journal: Current medical research and opinion 20050101
Title: Study of the liquid chromatography retention of some fibrate-type antihyperlipidemic drugs on C18 and CN columns: application for quantitation in pharmaceutical formulations.
Journal: Journal of AOAC International 20050101
Title: A two-dimensional electrophoresis preliminary approach to human hepatocarcinoma differentiation induced by PPAR-agonists.
Journal: Journal of cellular and molecular medicine 20050101
Title: [Dyslipidaemia and diabetes mellitus].
Journal: Revue medicale de Liege 20050101
Title: Mechanisms of calcium release from the sarcoplasmic reticulum in skeletal muscle.
Journal: Advances in experimental medicine and biology 20050101
Title: The effect of ciprofibrate on flow-mediated dilation and inflammatory markers in patients with combined hyperlipidemia.
Journal: Endothelium : journal of endothelial cell research 20050101
Title: Enzymatic examination of potential interaction between statins or fibrates and consumed Tricholoma equestre.
Journal: Przeglad lekarski 20050101
Title: Macrodissection versus microdissection of rectal carcinoma: minor influence of stroma cells to tumor cell gene expression profiles.
Journal: BMC genomics 20050101
Title: Single and chronic administration of ciprofibrate or of ciprofibrate-glycinate in male Fischer 344 rats: comparison of the effects on morphological and biochemical parameters in liver and blood.
Journal: European journal of drug metabolism and pharmacokinetics 20050101
Title: Evaluation of the carcinogenic potential of clofibrate in the neonatal mouse.
Journal: International journal of toxicology 20050101
Title: Peroxisome proliferator-activated receptor-gamma and its agonists in hypertension and atherosclerosis : mechanisms and clinical implications.
Journal: American journal of cardiovascular drugs : drugs, devices, and other interventions 20050101
Title: Hypertriglyceridemia, the coronary heart disease risk marker 'solved'.
Journal: Acta physiologica Hungarica 20050101
Title: [Variability in primary care drug prescription in 2003 in Castile-la Mancha, Spain].
Journal: Revista espanola de salud publica 20050101
Title: [Fibrate-induced increase in serum creatinine levels: two cases].
Journal: Therapie 20050101
Title: Suitability of hollow fibre liquid-phase microextraction for the determination of acidic pharmaceuticals in wastewater by liquid chromatography-electrospray tandem mass spectrometry without matrix effects.
Journal: Journal of chromatography. A 20041217
Title: Acute and chronic effects of clofibrate and clofibric acid on the enzymes acetylcholinesterase, lactate dehydrogenase and catalase of the mosquitofish, Gambusia holbrooki.
Journal: Chemosphere 20041201
Title: Lipid lowering drugs prescription and the risk of peripheral neuropathy: an exploratory case-control study using automated databases.
Journal: Journal of epidemiology and community health 20041201
Title: Incidence of hospitalized rhabdomyolysis in patients treated with lipid-lowering drugs.
Journal: JAMA 20041201
Title: Induction of phytohormones and differential gene expression in citrus flowers infected by the fungus Colletotrichum acutatum.
Journal: Molecular plant-microbe interactions : MPMI 20041201
Title: Therapeutic approaches to raising plasma HDL-cholesterol levels.
Journal: Nature clinical practice. Cardiovascular medicine 20041201
Title: [Low HDL-cholesterol, high triglycerides--well known but often ignored].
Journal: Praxis 20041110
Title: Lipid lowering effects of statins and fibrates in the management of HIV dyslipidemias associated with antiretroviral therapy in HIV clinical practice.
Journal: The Journal of infection 20041101
Title: Clofibric and ethacrynic acids prevent experimental pyelonephritis by Escherichia coli in mice.
Journal: FEMS immunology and medical microbiology 20041101
Title: Statin and fibrate treatment of combined hyperlipidemia: the effects on some novel risk factors.
Journal: Thrombosis and haemostasis 20041101
Title: Down regulation of hepatic PPARalpha function by AhR ligand.
Journal: The Journal of veterinary medical science 20041101
Title: Peroxisome proliferator-activated receptors as regulators of lipid metabolism; tissue differential expression in adipose tissues during cold acclimatization and hibernation of jerboa (Jaculus orientalis).
Journal: Biochimie 20041101
Title: Pharmaceuticals and personal care products (PPCPs) and endocrine disrupting chemicals (EDCs) in stormwater canals and Bayou St. John in New Orleans, Louisiana, USA.
Journal: The Science of the total environment 20041015
Title: Activation of peroxisome proliferator-activated receptor alpha in rat spinal cord after peripheral noxious stimulation.
Journal: Neuroscience letters 20041007
Title: The effect of statins and fibrates on interferon-gamma and interleukin-2 release in patients with primary type II dyslipidemia.
Journal: Atherosclerosis 20041001
Title: Raising high-density lipoprotein cholesterol with inhibitors of cholesteryl ester transfer protein - a new approach to coronary artery disease.
Journal: Expert opinion on investigational drugs 20041001
Title: Determination of some acidic drugs in surface and sewage treatment plant waters by capillary electrophoresis-electrospray ionization-mass spectrometry.
Journal: Electrophoresis 20041001
Title: Management of dyslipidaemia in HIV-infected patients receiving antiretroviral therapy.
Journal: Antiviral therapy 20041001
Title: Co-induction of methyltransferase Rv0560c by naphthoquinones and fibric acids suggests attenuation of isoprenoid quinone action in Mycobacterium tuberculosis.
Journal: Canadian journal of microbiology 20041001
Title: PPARalpha-dependent modulation of hepatic CYP1A by clofibric acid in rats.
Journal: Archives of toxicology 20040901
Title: Fibrates induce hepatic peroxisome and mitochondrial proliferation without overt evidence of cellular proliferation and oxidative stress in cynomolgus monkeys.
Journal: Carcinogenesis 20040901
Title: Therapeutic approaches in the prevention of cardiovascular disease in metabolic syndrome and in patients with type 2 diabetes.
Journal: Current opinion in cardiology 20040901
Title: Diabetes mellitus and unstable coronary artery disease: improved clinical outcome of coronary artery stenting in an era of glycoprotein IIb/IIIa inhibitors and lipid-lowering therapy.
Journal: Coronary artery disease 20040901
Title: Utility of currently available modes of therapy in reaching lipid goals.
Journal: The Journal of the American Osteopathic Association 20040901
Title: Coadministration of multidrug therapy to achieve lipid goals.
Journal: The Journal of the American Osteopathic Association 20040901
Title: Peroxisome proliferator-activated receptor (PPAR)-alpha: a pharmacological target with a promising future.
Journal: Pharmaceutical research 20040901
Title: PPARalpha agonists stimulate progastrin production in human colorectal carcinoma cells.
Journal: Regulatory peptides 20040815
Title: Effects of vitamin E on the NF-kappaB pathway in rats treated with the peroxisome proliferator, ciprofibrate.
Journal: Toxicology and applied pharmacology 20040815
Title: Analysis by liquid chromatography-electrospray ionization tandem mass spectrometry and acute toxicity evaluation for beta-blockers and lipid-regulating agents in wastewater samples.
Journal: Journal of chromatography. A 20040813
Title: Statins but not fibrates are associated with a reduced risk of venous thromboembolism: a hospital-based case-control study.
Journal: Fundamental & clinical pharmacology 20040801
Title: Protective behavior survey, West Nile virus, British Columbia.
Journal: Emerging infectious diseases 20040801
Title: Leaching behaviour of pharmaceuticals in soil-testing-systems: a part of an environmental risk assessment for groundwater protection.
Journal: The Science of the total environment 20040726
Title: PPARalpha agonists clofibrate and gemfibrozil inhibit cell growth, down-regulate hCG and up-regulate progesterone secretions in immortalized human trophoblast cells.
Journal: Biochemical pharmacology 20040715
Title: Effects of peroxisome proliferator-activated receptor alpha activation on pathways contributing to cholesterol homeostasis in rat hepatocytes.
Journal: Biochimica et biophysica acta 20040705
Title: Gastrointestinally distributed UDP-glucuronosyltransferase 1A10, which metabolizes estrogens and nonsteroidal anti-inflammatory drugs, depends upon phosphorylation.
Journal: The Journal of biological chemistry 20040702
Title: The peroxisome proliferator-activated receptor alpha (PPARalpha) agonist ciprofibrate inhibits apolipoprotein B mRNA editing in low density lipoprotein receptor-deficient mice: effects on plasma lipoproteins and the development of atherosclerotic lesions.
Journal: The Journal of biological chemistry 20040702
Title: Mitochondrial respiratory chain dysfunction, a non-receptor-mediated effect of synthetic PPAR-ligands: biochemical and pharmacological implications.
Journal: Biochemical and biophysical research communications 20040702
Title: Adiponectin in peritoneal dialysis patients: a comparison with hemodialysis patients and subjects with normal renal function.
Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 20040601
Title: Statin and fibrate associated myopathy: study of eight patients.
Journal: Arquivos de neuro-psiquiatria 20040601
Title: Sexually dimorphic metabolism of branched-chain lipids in C57BL/6J mice.
Journal: Journal of lipid research 20040501
Title: Environmental risk assessment of six human pharmaceuticals: are the current environmental risk assessment procedures sufficient for the protection of the aquatic environment?
Journal: Environmental toxicology and chemistry 20040501
Title: Highlights from the 74th Congress of the European Atherosclerosis Society.
Journal: Timely topics in medicine. Cardiovascular diseases 20040501
Title: Characterization of the species-specificity of peroxisome proliferators in rat and human hepatocytes.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20040401
Title: Regulation of apoptosis by peroxisome proliferators.
Journal: Toxicology letters 20040401
Title: Properties of an alginate gel bead containing a chitosan-drug salt.
Journal: Biological & pharmaceutical bulletin 20040301
Title: Liquid chromatography with triple-quadrupole or quadrupole-time of flight mass spectrometry for screening and confirmation of residues of pharmaceuticals in water.
Journal: Analytical and bioanalytical chemistry 20040201
Title: Evaluation of the dermal subchronic toxicity of phenoxyethyl isobutyrate in the rat.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20040201
Title: Kinetic study of photocatalytic degradation of carbamazepine, clofibric acid, iomeprol and iopromide assisted by different TiO2 materials--determination of intermediates and reaction pathways.
Journal: Water research 20040201
Title: Two-step liquid-liquid-liquid microextraction of nonsteroidal antiinflammatory drugs in wastewater.
Journal: Analytical chemistry 20040101
Title: In vitro reactivity of carboxylic acid-CoA thioesters with glutathione.
Journal: Chemical research in toxicology 20040101
Title: Miniaturized fluorescent RNA dot blot method for rapid quantitation of gene expression.
Journal: BMC biotechnology 20040101
Title: Application of UV-derivative spectra for determination of four antihyperlipidaemic drugs in pharmaceutical formulations.
Journal: Acta poloniae pharmaceutica 20040101
Title: Role of fibric acid derivatives in the management of risk factors for coronary heart disease.
Journal: Drugs 20040101
Title: Transport of pharmaceutically active compounds in saturated laboratory columns.
Journal: Ground water 20040101
Title: Effects of advanced oxidation processes (AOPs) on the toxicity of a mixture of pharmaceuticals.
Journal: Water science and technology : a journal of the International Association on Water Pollution Research 20040101
Title: Toxic effect of pharmaceuticals on methanogenesis.
Journal: Water science and technology : a journal of the International Association on Water Pollution Research 20040101
Title: Comparative effects of lipid-lowering therapies.
Journal: Progress in cardiovascular diseases 20040101
Title: Overexpression of SR-BI by adenoviral vector reverses the fibrateinduced hypercholesterolemia of apolipoprotein E-deficient mice.
Journal: The Journal of biological chemistry 20031226
Title: Determination of acidic pharmaceuticals, antibiotics and ivermectin in river sediment using liquid chromatography-tandem mass spectrometry.
Journal: Journal of chromatography. A 20031222
Title: Cardiovascular disease with diabetes or the metabolic syndrome: should statins or fibrates be first line lipid therapy?
Journal: Current opinion in lipidology 20031201
Title: Liver gene expression profiles of rats treated with clofibric acid: comparison of whole liver and laser capture microdissected liver.
Journal: The American journal of pathology 20031201
Title: Occurrence of neutral and acidic drugs in the effluents of Canadian sewage treatment plants.
Journal: Environmental toxicology and chemistry 20031201
Title: Distribution of acidic and neutral drugs in surface waters near sewage treatment plants in the lower Great Lakes, Canada.
Journal: Environmental toxicology and chemistry 20031201
Title: p-Chlorophenoxyisobutyric acid impairs auxin response in Arabidopsis root.
Journal: Plant physiology 20031101
Title: Ozonation and H2O2/UV treatment of clofibric acid in water: a kinetic investigation.
Journal: Journal of hazardous materials 20031031
Title: Determination of selected human pharmaceutical compounds in effluent and surface water samples by high-performance liquid chromatography-electrospray tandem mass spectrometry.
Journal: Journal of chromatography. A 20031010
Title: Cell proliferation and apoptosis are altered in mice deficient in the NF-kappaB p50 subunit after treatment with the peroxisome proliferator ciprofibrate.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20031001
Title: Pharmaceutical and personal care products in sewage treatment works.
Journal: Journal of environmental monitoring : JEM 20031001
Title: Hypertriglyceridemia increases mitochondrial resting respiration and susceptibility to permeability transition.
Journal: Journal of bioenergetics and biomembranes 20031001
Title: Liver gene expression in rats in response to the peroxisome proliferator-activated receptor-alpha agonist ciprofibrate.
Journal: Physiological genomics 20030929
Title: Simultaneous determination of clofibrate and its active metabolite clofibric acid in human plasma by reversed-phase high-performance liquid chromatography with ultraviolet absorbance detection.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20030905
Title: Fate of pharmaceuticals--photodegradation by simulated solar UV-light.
Journal: Chemosphere 20030901
Title: Effects of clofibric acid on mRNA expression profiles in primary cultures of rat, mouse and human hepatocytes.
Journal: Toxicology and applied pharmacology 20030901
Title: Ethylene promotes the induction by auxin of the cortical microtubule randomization required for low-pH-induced root hair initiation in lettuce (Lactuca sativa L.) seedlings.
Journal: Plant & cell physiology 20030901
Title: Influence of etofibrate on LDL-subtype distribution in patients with diabetic dyslipoproteinemia.
Journal: Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 20030901
Title: The peroxisome-proliferator-activated receptor alpha agonist ciprofibrate severely aggravates hypercholesterolaemia and accelerates the development of atherosclerosis in mice lacking apolipoprotein E.
Journal: The Biochemical journal 20030801
Title: Chromatin sphingomyelin changes in cell proliferation and/or apoptosis induced by ciprofibrate.
Journal: Journal of cellular physiology 20030801
Title: Action of ciprofibrate in type IIb hyperlipoproteinemia: modulation of the atherogenic lipoprotein phenotype and stimulation of high-density lipoprotein-mediated cellular cholesterol efflux.
Journal: The Journal of clinical endocrinology and metabolism 20030801
Title: [Long-term hypolipidemic treatment of mixed hyperlipidemia with a combination of statins and fibrates].
Journal: Casopis lekaru ceskych 20030801
Title: Reshaping the dyslipidemia management paradigm.
Journal: Postgraduate medicine 20030801
Title: CHD risk equivalents and the metabolic syndrome. Trial evidence supports aggressive management.
Journal: Postgraduate medicine 20030801
Title: Pharmaceuticals and personal care products (PPCPs) in surface and treated waters of Louisiana, USA and Ontario, Canada.
Journal: The Science of the total environment 20030720
Title: Ecotoxicological impact of pharmaceuticals found in treated wastewaters: study of carbamazepine, clofibric acid, and diclofenac.
Journal: Ecotoxicology and environmental safety 20030701
Title: Fibrates and renal function.
Journal: Clinical nephrology 20030701
Title: LDL-cholesterol, HDL-cholesterol or triglycerides--which is the culprit?
Journal: Diabetes research and clinical practice 20030701
Title: Short-term tests with a pilot sewage plant and biofilm reactors for the biological degradation of the pharmaceutical compounds clofibric acid, ibuprofen, and diclofenac.
Journal: The Science of the total environment 20030620
Title: Peroxisome proliferator-activated receptor ligands affect growth-related gene expression in human leukemic cells.
Journal: The Journal of pharmacology and experimental therapeutics 20030601
Title: Serum lipid comparison in patients treated by statins or fibrates: existence of bad HDL-C responders to statins.
Journal: Acta cardiologica 20030601
Title: [Ciprofibrate-induced acute cholestatic hepatitis].
Journal: Annales d'endocrinologie 20030601
Title: UDP-glucuronosyltransferase-dependent bioactivation of clofibric acid to a DNA-damaging intermediate in mouse hepatocytes.
Journal: Chemico-biological interactions 20030506
Title: Identification of coenzyme A-related tolmetin metabolites in rats: relationship with reactive drug metabolites.
Journal: Xenobiotica; the fate of foreign compounds in biological systems 20030501
Title: Molecular profiling of hepatocellular carcinomas developing spontaneously in acyl-CoA oxidase deficient mice: comparison with liver tumors induced in wild-type mice by a peroxisome proliferator and a genotoxic carcinogen.
Journal: Carcinogenesis 20030501
Title: Regulation by carbohydrate and clofibric acid of palmitoyl-CoA chain elongation in the liver of rats.
Journal: Lipids 20030501
Title: Determination of polar pharmaceuticals in sewage water of Greece by gas chromatography-mass spectrometry.
Journal: Chemosphere 20030401
Title: Occurrence and fate of carbamazepine, clofibric acid, diclofenac, ibuprofen, ketoprofen, and naproxen in surface waters.
Journal: Environmental science & technology 20030315
Title: Pharmaceuticals in STP effluents and their solar photodegradation in aquatic environment.
Journal: Chemosphere 20030301
Title: Cell-specific toxicity of fibrates in human embryonal rhabdomyosarcoma cells.
Journal: Naunyn-Schmiedeberg's archives of pharmacology 20030301
Title: Fibrates and medroxyprogesterone acetate induce apoptosis of primary Burkitt's lymphoma cells and cell lines: potential for applying old drugs to a new disease.
Journal: Leukemia 20030301
Title: Antral G cells in rats during dosing with a PPAR alpha agonist: a morphometric and immunocytochemical study.
Journal: Medical electron microscopy : official journal of the Clinical Electron Microscopy Society of Japan 20030301
Title: What future for combination therapies?
Journal: International journal of clinical practice. Supplement 20030301
Title: Peroxisome proliferator-activated receptor alpha (PPARalpha)-mediated regulation of multidrug resistance 2 (Mdr2) expression and function in mice.
Journal: The Biochemical journal 20030201
Title: Peroxisome proliferator ameliorates endothelial dysfunction in a murine model of hyperhomocysteinemia.
Journal: American journal of physiology. Lung cellular and molecular physiology 20030201
Title: Fibrates and C-reactive protein.
Journal: Clinica chimica acta; international journal of clinical chemistry 20030201
Title: Inhibition of TNF-alpha-induced RANTES expression in human hepatocyte-derived cells by fibrates, the hypolipidemic drugs.
Journal: International immunopharmacology 20030201
Title: Fibrates down-regulate IL-1-stimulated C-reactive protein gene expression in hepatocytes by reducing nuclear p50-NFkappa B-C/EBP-beta complex formation.
Journal: Blood 20030115
Title: Induction of hepatic ABC transporter expression is part of the PPARalpha-mediated fasting response in the mouse.
Journal: Gastroenterology 20030101
Title: Different effects of the liver mitogens triiodo-thyronine and ciprofibrate on the development of rat hepatocellular carcinoma.
Journal: Toxicologic pathology 20030101
Title: [Conjugation reactions of ciprofibrate with human and laboratory animals].
Journal: Arzneimittel-Forschung 20030101
Title: Evidence of cytochrome P450-catalyzed cleavage of the ether bond of phenoxybutyrate herbicides in Rhodococcus erythropolis K2-3.
Journal: Biodegradation 20030101
Title: A comprehensive description of muscle symptoms associated with lipid-lowering drugs.
Journal: Cardiovascular drugs and therapy 20030101
Title: Clofibric acid stimulates branched-chain amino acid catabolism by three mechanisms.
Journal: Archives of biochemistry and biophysics 20021115
Title: Effects of various fibrates on serum alkaline phosphatase activity.
Journal: Atherosclerosis 20021101
Title: In vivo and in vitro induction of cytochrome P450 enzymes in beagle dogs.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20021101
Title: Dysbetalipoproteinaemia--clinical and pathophysiological features.
Journal: South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 20021101
Title: Peroxisome proliferators compete and ameliorate Hcy-mediated endocardial endothelial cell activation.
Journal: American journal of physiology. Cell physiology 20021001
Title: Effect of ciprofibrate on lipoproteins, fibrinogen, renal function, and hepatic enzymes.
Journal: Journal of cardiovascular pharmacology and therapeutics 20021001
Title: PPAR alpha stimulates the rat gastrin-producing cell.
Journal: Molecular and cellular endocrinology 20020930
Title: Differentiated properties of hepatocytes induced from pancreatic cells.
Journal: Hepatology (Baltimore, Md.) 20020901
Title: Removal of pharmaceuticals during drinking water treatment.
Journal: Environmental science & technology 20020901
Title: Current drug treatments for lipid management.
Journal: Managed care (Langhorne, Pa.) 20020901
Title: Drugs and personal care products as ubiquitous pollutants: occurrence and distribution of clofibric acid, caffeine and DEET in the North Sea.
Journal: The Science of the total environment 20020805
Title: HMG-CoA reductase inhibition and PPAR- alpha activation both inhibit cyclosporin A induced endothelin-1 secretion in cultured endothelial cells.
Journal: Clinical science (London, England : 1979) 20020801
Title: Ciglitazone inhibits plasmin-induced proinflammatory monocyte activation via modulation of p38 MAP kinase activity.
Journal: Thrombosis and haemostasis 20020801
Title: Fibrates suppress chenodeoxycholic acid-induced RANTES expression through inhibition of NF-kappaB activation.
Journal: European journal of pharmacology 20020712
Title: Peroxisome proliferator-activated receptor agonists, hyperlipidaemia, and atherosclerosis.
Journal: Pharmacology & therapeutics 20020701
Title: Detection of pharmaceutical contaminations of river, pond, and tap water from Cologne (Germany) and surroundings.
Journal: International journal of hygiene and environmental health 20020701
Title: Molecular modelling of the peroxisome proliferator-activated receptor alpha (PPAR alpha) from human, rat and mouse, based on homology with the human PPAR gamma crystal structure.
Journal: Toxicology in vitro : an international journal published in association with BIBRA 20020601
Title: PPARalpha suppresses insulin secretion and induces UCP2 in insulinoma cells.
Journal: Journal of lipid research 20020601
Title: Occurrence, fate, and removal of pharmaceutical residues in the aquatic environment: a review of recent research data.
Journal: Toxicology letters 20020510
Title: Mechanism of constrictive vascular remodeling by homocysteine: role of PPAR.
Journal: American journal of physiology. Cell physiology 20020501
Title: Analysis of acidic drugs in the effluents of sewage treatment plants using liquid chromatography-electrospray ionization tandem mass spectrometry.
Journal: Journal of chromatography. A 20020405
Title: The peroxisome proliferator-activated receptor alpha-selective activator ciprofibrate upregulates expression of genes encoding fatty acid oxidation and ketogenesis enzymes in rat brain.
Journal: Neuropharmacology 20020401
Title: Cytochemical and biochemical demonstration of an ATPase in membranes of human peroxisomes.
Journal: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 20020301
Title: Analysis of serious adverse events. Lipid-lowering therapy revisited.
Journal: Canadian family physician Medecin de famille canadien 20020301
Title: Tolerability of statin-fibrate and statin-niacin combination therapy in dyslipidemic patients at high risk for cardiovascular events.
Journal: The American journal of cardiology 20020215
Title: Synergistic effect of 4-hydroxynonenal and PPAR ligands in controlling human leukemic cell growth and differentiation.
Journal: Free radical biology & medicine 20020201
Title: Atorvastatin versus four statin-fibrate combinations in patients with familial combined hyperlipidaemia.
Journal: Journal of cardiovascular risk 20020201
Title: Lipids in type 2 diabetes.
Journal: Seminars in vascular medicine 20020201
Title: Clofibric acid down-regulation of metallothionein IIA in HepG2 human hepatoma cells.
Journal: Biochemical pharmacology 20020115
Title: Fibrate and statin synergistically increase the transcriptional activities of PPARalpha/RXRalpha and decrease the transactivation of NFkappaB.
Journal: Biochemical and biophysical research communications 20020111
Title: Studies on the reactivity of clofibryl-S-acyl-CoA thioester with glutathione in vitro.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20020101
Title: Organ distribution of multidrug resistance proteins 1, 2, and 3 (Mrp1, 2, and 3) mRNA and hepatic induction of Mrp3 by constitutive androstane receptor activators in rats.
Journal: The Journal of pharmacology and experimental therapeutics 20020101
Title: Effect of ciprofibrate on C-reactive protein and fibrinogen levels.
Journal: Angiology 20020101
Title: Prevention/reversal of choline deficiency-induced steatohepatitis by a peroxisome proliferator-activated receptor alpha ligand in rats.
Journal: In vivo (Athens, Greece) 20020101
Title: Combined treatment with fibrates and small doses of atorvastatin in patients with mixed hyperlipidemia.
Journal: Current medical research and opinion 20020101
Title: Use of dominant negative nuclear receptors to study xenobiotic-inducible gene expression in primary cultured hepatocytes.
Journal: Journal of pharmacological and toxicological methods 20020101
Title: Nafenopin-, ciprofibroyl-, and palmitoyl-CoA conjugation in vitro: kinetic and molecular characterization of marmoset liver microsomes and expressed MLCL1.
Journal: Archives of biochemistry and biophysics 20011201
Title: Effects of fibrates on plasma prothrombotic activity in patients with type IIb dyslipidemia.
Journal: International journal of clinical pharmacology and therapeutics 20011201
Title: Occurrence of pharmaceutical contaminants and screening of treatment alternatives for southeastern Louisiana.
Journal: Annals of the New York Academy of Sciences 20011201
Title: Ciprofibrate increases plasma concentration of platelet-derived growth factor AB in patients with advanced atherosclerosis and hyperlipidemia independently of its hypolipidemic effects.
Journal: Journal of cardiovascular pharmacology 20011101
Title: Differential induction of peroxisomal beta-oxidation enzymes by clofibric acid and aspirin in piglet tissues.
Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20011101
Title: Fibrates suppress bile acid synthesis via peroxisome proliferator-activated receptor-alpha-mediated downregulation of cholesterol 7alpha-hydroxylase and sterol 27-hydroxylase expression.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20011101
Title: Ciprofibrate versus gemfibrozil in the treatment of mixed hyperlipidemias: an open-label, multicenter study.
Journal: Metabolism: clinical and experimental 20011101
Title: Metabolic alterations by clofibric acid in the formation of molecular species of phosphatidylcholine in rat liver.
Journal: Biochemical pharmacology 20011001
Title: Properties of Ca(2+) release induced by clofibric acid from the sarcoplasmic reticulum of mouse skeletal muscle fibres.
Journal: British journal of pharmacology 20011001
Title: Effects of dantrolene and its derivatives on Ca(2+) release from the sarcoplasmic reticulum of mouse skeletal muscle fibres.
Journal: British journal of pharmacology 20011001
Title: Carboxylic acids and skeletal muscle chloride channel conductance: effects on the biological activity induced by the introduction of an aryloxyalkyl group alpha to the carboxylic function of 4-chloro-phenoxyacetic acid.
Journal: Farmaco (Societa chimica italiana : 1989) 20011001
Title: Selective degradation of ibuprofen and clofibric acid in two model river biofilm systems.
Journal: Water research 20010901
Title: Drastic reduction of the slow gate of human muscle chloride channel (ClC-1) by mutation C277S.
Journal: The Journal of physiology 20010801
Title: Activation of the activator protein-1 by the peroxisome proliferator clofibric acid in rat H4IIEC3 hepatoma cells.
Journal: Toxicology and applied pharmacology 20010801
Title: Interaction of gamma-glutamyltranspeptidase with clofibryl-S-acyl-glutathione in vitro and in vivo in rat.
Journal: Chemical research in toxicology 20010801
Title: Fibrate-induced increase in blood urea and creatinine.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20010701
Title: Fibrate treatment can increase serum creatinine levels.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20010601
Title: Ciprofibrate versus gemfibrozil in the treatment of mixed hyperlipidemias: an open-label, multicenter study.
Journal: Metabolism: clinical and experimental 20010601
Title: Suppression of hepatocyte nuclear factor-4alpha by acyl-CoA thioesters of hypolipidemic peroxisome proliferators.
Journal: Biochemical pharmacology 20010501
Title: [Effect of ciprofibrate on the endothelial dysfunction of patients with combined dyslipidemia].
Journal: Orvosi hetilap 20010415
Title: Impressive lipid changes following hypolipidaemic drug administration can unveil subclinical hyperthyroidism.
Journal: Diabetes, obesity & metabolism 20010401
Title: Reversible binding of the novel anti-tumour agent 5,6-dimethylxanthenone-4-acetic acid to plasma proteins and its distribution into blood cells in various species.
Journal: The Journal of pharmacy and pharmacology 20010401
Title: Homocysteine elevation with fibrates: is it a class effect?
Journal: The Israel Medical Association journal : IMAJ 20010401
Title: Simultaneous quantification of neutral and acidic pharmaceuticals and pesticides at the low-ng/l level in surface and waste water.
Journal: Journal of chromatography. A 20010316
Title: Assessment of P450 induction in the marmoset monkey using targeted anti-peptide antibodies.
Journal: Biochimica et biophysica acta 20010309
Title: Statin-fibrate combinations in patients with combined hyperlipedemia.
Journal: Atherosclerosis 20010301
Title: Carboxylic acids and skeletal muscle chloride channel conductance: effects on the biological activity induced by the introduction of methyl groups on the aromatic ring of chiral alpha-(4-chloro-phenoxy)alkanoic acids.
Journal: Farmaco (Societa chimica italiana : 1989) 20010301
Title: Determination of drug residues in water by the combination of liquid chromatography or capillary electrophoresis with electrospray mass spectrometry.
Journal: Journal of chromatography. A 20010223
Title: Effects of etofibrate upon the metabolism of chylomicron-like emulsions in patients with coronary artery disease.
Journal: Atherosclerosis 20010201
Title: Differential induction of stearoyl-CoA desaturase and acyl-CoA oxidase genes by fibrates in HepG2 cells.
Journal: Biochemical pharmacology 20010201
Title: Etofibrate but not controlled-release niacin decreases LDL cholesterol and lipoprotein (a) in type IIb dyslipidemic subjects.
Journal: Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20010201
Title: Diabetes: statins, fibrates, or both?
Journal: Current atherosclerosis reports 20010101
Title: The role of fibric acids in atherosclerosis.
Journal: Current atherosclerosis reports 20010101
Title: Treatment of dyslipoproteinemia in the metabolic syndrome.
Journal: Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 20010101
Title: Statin-fibrate combination therapy.
Journal: The Annals of pharmacotherapy 20010101
Title: Hypertriglyceridemia: associated risks and effect of drug treatment.
Journal: American journal of cardiovascular drugs : drugs, devices, and other interventions 20010101
Title: Drug treatment of combined hyperlipidemia.
Journal: American journal of cardiovascular drugs : drugs, devices, and other interventions 20010101
Title: Fibrate-induced increase in blood urea and creatinine: is gemfibrozil the only innocuous agent?
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20001201
Title: CYP2A5/CYP2A6 expression in mouse and human hepatocytes treated with various in vivo inducers.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20001101
Title: Pharmacological characterization of chloride channels belonging to the ClC family by the use of chiral clofibric acid derivatives.
Journal: Molecular pharmacology 20000901
Title: Detection of chemical-induced differential expression of rat hepatic cytochrome P450 mRNA transcripts using branched DNA signal amplification technology.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20000501
Title: Differential induction of hepatic drug-metabolizing enzymes by fenvaleric acid in male rats.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 19991201
Title: Fibrates, dyslipoproteinaemia and cardiovascular disease.
Journal: Current opinion in lipidology 19991201
Title: A ureido-thioisobutyric acid (GW9578) is a subtype-selective PPARalpha agonist with potent lipid-lowering activity.
Journal: Journal of medicinal chemistry 19990923
Title: Effects of fibrate compounds on expression of plasminogen activator inhibitor-1 by cultured endothelial cells.
Journal: Arteriosclerosis, thrombosis, and vascular biology 19990601
Title: Statin + fibrate combination therapy fluvastatin with bezafibrate or ciprofibrate in high risk patients with vascular disease.
Journal: International journal of cardiology 19990601
Title: Insulin differentially affects xenobiotic-enhanced, cytochrome P-450 (CYP)2E1, CYP2B, CYP3A, and CYP4A expression in primary cultured rat hepatocytes.
Journal: The Journal of pharmacology and experimental therapeutics 19990501
Title: Fibrates suppress fibrinogen gene expression in rodents via activation of the peroxisome proliferator-activated receptor-alpha.
Journal: Blood 19990501
Title: Fibrate-modulated expression of fibrinogen, plasminogen activator inhibitor-1 and apolipoprotein A-I in cultured cynomolgus monkey hepatocytes -- role of the peroxisome proliferator-activated receptor-alpha.
Journal: Thrombosis and haemostasis 19981201
Title: Mechanisms of peroxisome proliferation by perfluorooctanoic acid and endogenous fatty acids.
Journal: General pharmacology 19980801
Title: Clinical pharmacokinetics of fibric acid derivatives (fibrates).
Journal: Clinical pharmacokinetics 19980201
Title: The role of phosphatidylethanolamine methylation in the secretion of very low density lipoproteins by cultured rat hepatocytes: rapid inhibition of phosphatidylethanolamine methylation by bezafibrate increases the density of apolipoprotein B48-containing lipoproteins.
Journal: Biochimica et biophysica acta 19961111
Title: Growth regulation by peroxisome proliferators: opposing activities in early and late G1.
Journal: Cancer research 19960715
Title: Oltipraz-mediated changes in aflatoxin B(1) biotransformation in rat liver: implications for human chemointervention.
Journal: Cancer research 19960515
Title: Flow cytometric analysis of neoplastic nodules and hepatocellular carcinomas induced by ciprofibrate in the rat.
Journal: British journal of cancer 19960101
Title: [Rhabdomyolysis and unexplained malaise. Role of combination of ciprofibrate and norfloxacin].
Journal: La Revue de medecine interne 19960101
Title: Hypolipidemic activity of select fibrates correlates to changes in hepatic apolipoprotein C-III expression: a potential physiologic basis for their mode of action.
Journal: Journal of lipid research 19951201
Title: Currently available hypolipidaemic drugs and future therapeutic developments.
Journal: Bailliere's clinical endocrinology and metabolism 19951001
Title: The effects of diquat and ciprofibrate on mRNA expression and catalytic activities of hepatic xenobiotic metabolizing and antioxidant enzymes in rat liver.
Journal: Toxicology and applied pharmacology 19950901
Title: Xenobiotic-enhanced expression of cytochrome P450 2E1 and 2B1/2B2 in primary cultured rat hepatocytes.
Journal: Drug metabolism and disposition: the biological fate of chemicals 19950701
Title: The herbicide dicamba (2-methoxy-3,6-dichlorobenzoic acid) is a peroxisome proliferator in rats.
Journal: Fundamental and applied toxicology : official journal of the Society of Toxicology 19950601
Title: Effect of the peroxisome proliferators ciprofibrate and perfluorodecanoic acid on hepatic cell proliferation and toxicity in Sprague-Dawley rats.
Journal: Carcinogenesis 19941201
Title: The effects of clofibrate and bezafibrate on cholesterol metabolism in the liver of the male rat.
Journal: Lipids 19941101
Title: Antihyperlipidaemic agents. Drug interactions of clinical significance.
Journal: Drug safety 19941101
Title: A recombinant phenobarbital-inducible rat liver UDP-glucuronosyltransferase (UDP-glucuronosyltransferase 2B1) stably expressed in V79 cells catalyzes the glucuronidation of morphine, phenols, and carboxylic acids.
Journal: Molecular pharmacology 19940101
Title: Further studies on the involvement of selenium in peroxisome proliferation in rat liver. Comparison of effects with clofibric acid and perfluorooctanoic acid and the pharmacokinetics of [14C]clofibrate.
Journal: Biochemical pharmacology 19931117
Title: Coordinate induction of acyl-CoA binding protein, fatty acid binding protein and peroxisomal beta-oxidation by peroxisome proliferators.
Journal: Biochimica et biophysica acta 19930606
Title: Reinduction of the hypnotic effects of thiopental with NSAIDs by decreasing thiopental plasma protein binding in humans.
Journal: Acta anaesthesiologica Scandinavica 19930401
Title: Lack of peroxisomal enzyme inducibility in rat hepatic preneoplastic lesions induced by mutagenic carcinogens: contrasted expression of glutathione S-transferase P form and enoyl CoA hydratase.
Journal: Carcinogenesis 19930301
Title: Complementary deoxyribonucleic acid cloning and expression of a human liver uridine diphosphate-glucuronosyltransferase glucuronidating carboxylic acid-containing drugs.
Journal: The Journal of pharmacology and experimental therapeutics 19930101
Title: Analysis of activated protooncogenes in B6C3F1 mouse liver tumors induced by ciprofibrate, a potent peroxisome proliferator.
Journal: Carcinogenesis 19930101
Title: Mechanism of action of fibrates.
Journal: Postgraduate medical journal 19930101
Title: Convergence of 9-cis retinoic acid and peroxisome proliferator signalling pathways through heterodimer formation of their receptors.
Journal: Nature 19920827
Title: Regulation of HMG-CoA reductase, apoprotein-B and LDL receptor gene expression by the hypocholesterolemic drugs simvastatin and ciprofibrate in Hep G2, human and rat hepatocytes.
Journal: Biochimica et biophysica acta 19920709
Title: Plasma levels of HGF in rats treated with tumor promoters.
Journal: Carcinogenesis 19920101
Title: Peroxisome proliferation in neoplastic nodules and hepatocellular carcinomas induced by ciprofibrate in the rat.
Journal: Experimental pathology 19910101
Title: On the mechanism of the hepatocarcinogenicity of peroxisome proliferators.
Journal: Chemico-biological interactions 19910101
Title: Effects of gemfibrozil and other fibric acid derivatives on blood lipids and lipoproteins.
Journal: Journal of clinical pharmacology 19910101
Title: Characterization of the hepatic responses to the short-term administration of ciprofibrate in several rat strain. Co-induction of microsomal cytochrome P-450 IVA1 and peroxisome proliferation.
Journal: Biochemical pharmacology 19900901
Title: Peroxisome proliferator-induced alterations in the expression and modification of rat hepatocyte plasma membrane proteins.
Journal: Cancer research 19900201
Title: Studies with etofibrate in the rat. Part I: Effects on glycerol, free fatty acid and triacylglycerol metabolism.
Journal: Biochimica et biophysica acta 19881104
Title: Lack of expression of glutathione-S-transferase P, gamma-glutamyl transpeptidase, and alpha-fetoprotein messenger RNAs in liver tumors induced by peroxisome proliferators.
Journal: Cancer research 19880901
Title: Interactions of inhibitors of carnitine palmitoyltransferase I and fibrates in cultured hepatocytes.
Journal: The Biochemical journal 19880701
Title: Absence of gamma-glutamyltranspeptidase activity in lung metastasis in rats with hepatocellular carcinomas induced by ciprofibrate, a peroxisome proliferator.
Journal: Cancer letters 19871201
Title: Peroxisome proliferator-induced hepatocarcinogenesis: levels of activating and detoxifying enzymes in hepatocellular carcinomas induced by ciprofibrate.
Journal: Carcinogenesis 19870101
Title: Mitochondrial myopathy--a result of clofibrate/etofibrate treatment? Case report.
Journal: Acta neuropathologica 19850101
Title: Effect of bezafibrate on plasma lipids, lipoproteins, apolipoproteins AI, AII and B and LCAT activity in hyperlipidemic, non-insulin-dependent diabetics.
Journal: Atherosclerosis 19820601
Title: [Clofibrate therapy--current status from a gerontological viewpoint].
Journal: Zeitschrift fur Alternsforschung 19820101
Title: Forman BM, et, al. Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors alpha and delta. Proc Natl Acad Sci U S A. 1997 Apr 29;94(9):4312-7.
Title: Salgado R, et, al. Biodegradation of clofibric acid and identification of its metabolites. J Hazard Mater. 2012 Nov 30;241-242:182-9.
Title: Kawashima Y, et, al. Increased activity of stearoyl-CoA desaturation in liver from rat fed clofibric acid. Biochim Biophys Acta. 1982 Dec 13;713(3):622-8.