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885220-61-1,MFCD19443727
Catalog No.:AA00H2UG

885220-61-1 | GSK 561679A

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
95%
1 week  
$128.00   $90.00
- +
5mg
95%
1 week  
$267.00   $187.00
- +
10mg
95%
1 week  
$418.00   $292.00
- +
25mg
95%
1 week  
$662.00   $464.00
- +
50mg
95%
1 week  
$935.00   $655.00
- +
100mg
95%
1 week  
$1,292.00   $904.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00H2UG
Chemical Name:
GSK 561679A
CAS Number:
885220-61-1
Molecular Formula:
C22H26N6O2
Molecular Weight:
406.4808
MDL Number:
MFCD19443727
SMILES:
COc1ccc(c(c1)C)c1c(C)nn2c1nc(C)cc2N[C@H](c1onc(n1)C)CC
Properties
Computed Properties
 
Complexity:
568  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Heavy Atom Count:
30  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
6  
XLogP3:
4.5  

Literature

Title: Behavioral, biological, and chemical perspectives on targeting CRF(1) receptor antagonists to treat alcoholism.

Journal: Drug and alcohol dependence 20130301

Title: Discovery of NBI-77860/GSK561679, a potent corticotropin-releasing factor (CRF1) receptor antagonist with improved pharmacokinetic properties.

Journal: Bioorganic & medicinal chemistry letters 20101215

Title: Schwandt ML, et al. The CRF1 Antagonist Verucerfont in Anxious Alcohol-Dependent Women: Translation of Neuroendocrine, But not of Anti-Craving Effects. Neuropsychopharmacology. 2016 Nov;41(12):2818-2829.

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SDS
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Tags:885220-61-1 Molecular Formula|885220-61-1 MDL|885220-61-1 SMILES|885220-61-1 GSK 561679A