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89565-68-4,MFCD00864399
Catalog No.:AA003Y5X

89565-68-4 | Tropisetron

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1g
99%
in stock  
$39.00   $28.00
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5g
99%
in stock  
$152.00   $107.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA003Y5X
Chemical Name:
Tropisetron
CAS Number:
89565-68-4
Molecular Formula:
C17H20N2O2
Molecular Weight:
284.3529
MDL Number:
MFCD00864399
SMILES:
CN1[C@H]2CC[C@H]1CC(C2)OC(=O)c1c[nH]c2c1cccc2
Properties
Properties
 
Form:
Solid  
MP:
201-202℃  
Storage:
2-8℃;  

Computed Properties
 
Complexity:
400  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
2  
Heavy Atom Count:
21  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
3  
XLogP3:
3.8  

Downstream Synthesis Route

[1]CurrentPatentAssignee:KAMPPHARMACEUTICALS-CN106831754,2017,ALocationinpatent:Paragraph0012

[2]Langlois;Soulier;Yang;Bremont;Florac;Rampillon;Giudice[EuropeanJournalofMedicinalChemistry,1993,vol.28,#11,p.869-880]

[3]CurrentPatentAssignee:BUCKINSTITUTEFORRESEARCHONAGING-US11325904,2022,B2Locationinpatent:Page/Pagecolumn55

[4]CurrentPatentAssignee:BUCKINSTITUTEFORRESEARCHONAGING-US11325904,2022,B2Locationinpatent:Page/Pagecolumn55

89565-68-4    17341-93-4   
CASUnavailable 

[1]Maksay,Gabor;Nemes,Peter;Vincze,Zoltan;Biro,Timea[BioorganicandMedicinalChemistry,2008,vol.16,#4,p.2086-2092]

[1]CurrentPatentAssignee:KAMPPHARMACEUTICALS-CN106831754,2017,A

89565-68-4   
CASUnavailable 

[1]CurrentPatentAssignee:KAMPPHARMACEUTICALS-CN106831754,2017,ALocationinpatent:Paragraph0012

Literature

Title: Involvement of stimulation of α7 nicotinic acetylcholine receptors in the suppressive effect of tropisetron on dextran sulfate sodium-induced colitis in mice.

Journal: Journal of pharmacological sciences 20150301

Title: The neuroprotective effect of tropisetron on vincristine-induced neurotoxicity.

Journal: Neurotoxicology 20140301

Title: 5-HT(3) receptor mediates the dose-dependent effects of citalopram on pentylenetetrazole-induced clonic seizure in mice: involvement of nitric oxide.

Journal: Epilepsy research 20120901

Title: Short-term tropisetron treatment and cognitive and P50 auditory gating deficits in schizophrenia.

Journal: The American journal of psychiatry 20120901

Title: A general method for palladium-catalyzed direct carbonylation of indole with alcohol and phenol.

Journal: Organic letters 20120817

Title: The anti-inflammatory effects of the 5-HT₃ receptor antagonist tropisetron are mediated by the inhibition of p38 MAPK activation in primary human monocytes.

Journal: International immunopharmacology 20120801

Title: Tropisetron attenuates cardiac injury in a rat trauma-hemorrhage model.

Journal: Shock (Augusta, Ga.) 20120701

Title: Tropisetron and paracetamol association in post-operative patients.

Journal: Fundamental & clinical pharmacology 20120601

Title: Combination of dexamethasone and tropisetron before thyroidectomy to alleviate postoperative nausea, vomiting, and pain: randomized controlled trial.

Journal: World journal of surgery 20120601

Title: Evidence-based knee injections for the management of arthritis.

Journal: Pain medicine (Malden, Mass.) 20120601

Title: Regulation of respiratory-related hypoglossal motor output by α₁ adrenergic and serotonin 5-HT₃ receptor activation in isolated adult turtle brainstems.

Journal: Respiratory physiology & neurobiology 20120430

Title: Efficacy of dexamethasone added to ramosetron for preventing postoperative nausea and vomiting in highly susceptible patients following spine surgery.

Journal: Korean journal of anesthesiology 20120301

Title: [Comparison of the effect of palonosetron versus tropisetron in prevention of vomiting in patients receiving high dose cisplatin-based chemotherapy].

Journal: Zhonghua zhong liu za zhi [Chinese journal of oncology] 20120301

Title: Effects of OCT1 polymorphisms on the cellular uptake, plasma concentrations and efficacy of the 5-HT(3) antagonists tropisetron and ondansetron.

Journal: The pharmacogenomics journal 20120201

Title: Effect of intravenous tropisetron on modulation of pain and central hypersensitivity in chronic low back pain patients.

Journal: Pain 20120201

Title: One failed clinical trial (of 5HT3 antagonists) does not invalidate the concept.

Journal: Pain 20120201

Title: A network meta-analysis on the efficacy of serotonin type 3 receptor antagonists used in adults during the first 24 hours for postoperative nausea and vomiting prophylaxis.

Journal: Clinical therapeutics 20120201

Title: Prophylaxis of radiation-induced nausea and vomiting using 5-hydroxytryptamine-3 serotonin receptor antagonists: a systematic review of randomized trials.

Journal: International journal of radiation oncology, biology, physics 20120101

Title: Synergistic self-administration of ethanol and cocaine directly into the posterior ventral tegmental area: involvement of serotonin-3 receptors.

Journal: The Journal of pharmacology and experimental therapeutics 20120101

Title: [Low-dose droperidol in children: rescue therapy for persistent postoperative nausea and vomiting].

Journal: Der Anaesthesist 20120101

Title: Reappraisal of the role of dolasetron in prevention and treatment of nausea and vomiting associated with surgery or chemotherapy.

Journal: Cancer management and research 20120101

Title: Differentiated human midbrain-derived neural progenitor cells express excitatory strychnine-sensitive glycine receptors containing α2β subunits.

Journal: PloS one 20120101

Title: Protective effect of tropisetron on rodent hepatic injury after trauma-hemorrhagic shock through P38 MAPK-dependent hemeoxygenase-1 expression.

Journal: PloS one 20120101

Title: Discovery and development of α7 nicotinic acetylcholine receptor modulators.

Journal: Journal of medicinal chemistry 20111208

Title: Functional characterization and high-throughput screening of positive allosteric modulators of α7 nicotinic acetylcholine receptors in IMR-32 neuroblastoma cells.

Journal: Assay and drug development technologies 20111201

Title: Serotonin receptor type 3 antagonists improve obesity-associated fatty liver disease in mice.

Journal: The Journal of pharmacology and experimental therapeutics 20111201

Title: Experimental examination of anti-inflammatory effects of a 5-HT3 receptor antagonist, tropisetron, and concomitant effects on autonomic nervous function in a rat sepsis model.

Journal: International immunopharmacology 20111201

Title: Management of postoperative nausea and vomiting in women scheduled for breast cancer surgery.

Journal: Journal of anesthesia 20111201

Title: The serotonin-6 receptor as a novel therapeutic target.

Journal: Experimental neurobiology 20111201

Title: Ramosetron for the prevention of postoperative nausea and vomiting (PONV): a meta-analysis.

Journal: Korean journal of anesthesiology 20111101

Title: Transient expression of functional serotonin 5-HT3 receptors by glutamatergic granule cells in the early postnatal mouse cerebellum.

Journal: The Journal of physiology 20111015

Title: Tropisetron upregulates cannabinoid CB1 receptors in cerebellar granule cells: possible involvement of calcineurin.

Journal: Brain research 20111012

Title: Short-term synaptic plasticity regulates the level of olivocochlear inhibition to auditory hair cells.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20111012

Title: Single-dose palonosetron for prevention of chemotherapy-induced nausea and vomiting in patients with aggressive non-Hodgkin's lymphoma receiving moderately emetogenic chemotherapy containing steroids: results of a phase II study from the Gruppo Italiano per lo Studio dei Linfomi (GISL).

Journal: Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 20111001

Title: Efficacy and tolerability of transdermal granisetron for the control of chemotherapy-induced nausea and vomiting associated with moderately and highly emetogenic multi-day chemotherapy: a randomized, double-blind, phase III study.

Journal: Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 20111001

Title: Synergistic antiemetic interactions between serotonergic 5-HT3 and tachykininergic NK1-receptor antagonists in the least shrew (Cryptotis parva).

Journal: Pharmacology, biochemistry, and behavior 20111001

Title: Tropisetron versus metoclopramide for the treatment of nausea and vomiting in the emergency department: A randomized, double-blinded, clinical trial.

Journal: Emergency medicine Australasia : EMA 20111001

Title: [Efficacy and safety of palonosetron versus tropisetron in the prevention of highly emetogenic chemotherapy-induced acute and delayed vomiting in Chinese cancer patients].

Journal: Zhonghua yi xue za zhi 20110927

Title: Prophylaxis of postoperative nausea and vomiting in elective breast surgery.

Journal: Journal of clinical anesthesia 20110901

Title: The effects of jatrorrhizine on contractile responses of rat ileum.

Journal: European journal of pharmacology 20110801

Title: Profiling of a prescription drug library for potential renal drug-drug interactions mediated by the organic cation transporter 2.

Journal: Journal of medicinal chemistry 20110714

Title: The stimulating effects of ethanol on ventral tegmental area dopamine neurons projecting to the ventral pallidum and medial prefrontal cortex in female Wistar rats: regional difference and involvement of serotonin-3 receptors.

Journal: Psychopharmacology 20110701

Title: Lack of long-term behavioral alterations after early postnatal treatment with tropisetron: implications for developmental psychobiology.

Journal: Pharmacology, biochemistry, and behavior 20110701

Title: Species independence in brain tissue binding using brain homogenates.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20110701

Title: Acetylcholine and norepinephrine mediate GABAergic but not glycinergic transmission enhancement by melittin in adult rat substantia gelatinosa neurons.

Journal: Journal of neurophysiology 20110701

Title: Tropisetron increases the inhibitory effect of mild restraint on lordosis behavior of hormonally primed, ovariectomized rats.

Journal: Behavioural brain research 20110601

Title: Tropisetron blocks analgesic action of acetaminophen: a human pain model study.

Journal: Pain 20110601

Title: Antiemetic prophylaxis in thyroid surgery: a randomized, double-blind comparison of three 5-HT3 agents.

Journal: Journal of anesthesia 20110601

Title: The role of 5-HT(3) receptors in the additive anticonvulsant effects of citalopram and morphine on pentylenetetrazole-induced clonic seizures in mice.

Journal: Epilepsy & behavior : E&B 20110601

Title: Tropisetron ameliorates ischemic brain injury in an embolic model of stroke.

Journal: Brain research 20110525

Title: Mode of action of peppermint oil and (-)-menthol with respect to 5-HT3 receptor subtypes: binding studies, cation uptake by receptor channels and contraction of isolated rat ileum.

Journal: Phytotherapy research : PTR 20110501

Title: The pyramidal neurons in the medial prefrontal cortex show decreased response to 5-hydroxytryptamine-3 receptor stimulation in a rodent model of Parkinson's disease.

Journal: Brain research 20110412

Title: α7 Nicotinic acetylcholine receptors in the central amygdaloid nucleus alter naloxone-induced withdrawal following a single exposure to morphine.

Journal: Psychopharmacology 20110401

Title: Retraction Notice: Current review of ramosetron in the prevention of postoperative nausea and vomiting.

Journal: Current drug safety 20110401

Title: Cisplatin-induced emesis: systematic review and meta-analysis of the ferret model and the effects of 5-HT₃ receptor antagonists.

Journal: Cancer chemotherapy and pharmacology 20110301

Title: Management of postoperative nausea and vomiting in patients undergoing laparoscopic cholecystectomy.

Journal: Surgical endoscopy 20110301

Title: A structural and mutagenic blueprint for molecular recognition of strychnine and d-tubocurarine by different cys-loop receptors.

Journal: PLoS biology 20110301

Title: Anti-emetic drugs in oncology: pharmacology and individualization by pharmacogenetics.

Journal: International journal of clinical pharmacy 20110201

Title: Human plasma quantification of droperidol and ondansetron used in preventing postoperative nausea and vomiting with a LC/ESI/MS/MS method.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20110115

Title: A randomized comparison of droperidol, metoclopramide, tropisetron, and ondansetron for the prevention of postoperative nausea and vomiting.

Journal: Gynecologic and obstetric investigation 20110101

Title: Hippocampal deletion of BDNF gene attenuates gamma oscillations in area CA1 by up-regulating 5-HT3 receptor.

Journal: PloS one 20110101

Title: Characterizing ligand-gated ion channel receptors with genetically encoded Ca2++ sensors.

Journal: PloS one 20110101

Title: α7 nicotinic acetylcholine receptor as a potential therapeutic target for schizophrenia.

Journal: Current pharmaceutical design 20110101

Title: Analysis of multiple compound-protein interactions reveals novel bioactive molecules.

Journal: Molecular systems biology 20110101

Title: Why should gastroenterologists know about fibromyalgia? Common pathogenesis and clinical implications.

Journal: Journal of neurogastroenterology and motility 20110101

Title: Allogeneic hematopoietic stem cell transplantation for acute leukemia with Gilbert's syndrome.

Journal: Journal of hematology & oncology 20110101

Title: Getting the grip on nonspecific treatment effects: emesis in patients randomized to acupuncture or sham compared to patients receiving standard care.

Journal: PloS one 20110101

Title: BICEPP: an example-based statistical text mining method for predicting the binary characteristics of drugs.

Journal: BMC bioinformatics 20110101

Title: Genetic polymorphisms in the three malaysian races effect granisetron clinical antiemetic actions in breast cancer patients receiving chemotherapy.

Journal: Asian Pacific journal of cancer prevention : APJCP 20110101

Title: Palonosetron: A novel approach to control postoperative nausea and vomiting in day care surgery.

Journal: Saudi journal of anaesthesia 20110101

Title: Symptomatic sinus bradycardia: A rare adverse effect of intravenous ondansetron.

Journal: Saudi journal of anaesthesia 20110101

Title: [Development of new therapeutic drugs based on the pathophysiology of schizophrenia].

Journal: Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica 20110101

Title: Comparison of ondansetron and combination of ondansetron and dexamethasone as a prophylaxis for postoperative nausea and vomiting in adults undergoing elective laparoscopic surgery.

Journal: Journal of emergencies, trauma, and shock 20110101

Title: Prophylaxis of postoperative nausea and vomiting in adolescent patients: a review with emphasis on combination of fixed-dose ondansetron and transdermal scopolamine.

Journal: Journal of drug delivery 20110101

Title: Comment on Ekinci et al.: A randomized comparison of droperidol, metoclopramide, tropisetron, and ondansetron for the prevention of postoperative nausea and vomiting.

Journal: Gynecologic and obstetric investigation 20110101

Title: Treating nausea and vomiting in palliative care: a review.

Journal: Clinical interventions in aging 20110101

Title: Current concepts in the management of postoperative nausea and vomiting.

Journal: Anesthesiology research and practice 20110101

Title: The chemical basis of pharmacology.

Journal: Biochemistry 20101207

Title: Ameliorating effects of tropisetron on dopaminergic disruption of prepulse inhibition via the alpha(7) nicotinic acetylcholine receptor in Wistar rats.

Journal: Brain research 20100924

Title: Cardiovascular effects of a novel synthetic analogue of naturally occurring piperamides.

Journal: Journal of cardiovascular pharmacology 20100901

Title: Differential responses to serotonin receptor ligands in an impulsive-aggressive phenotype.

Journal: Behavioral neuroscience 20100801

Title: Anti-emetic doses of dexamethasone suppress cortisol response in laparoscopic cholecystectomy.

Journal: Anaesthesia and intensive care 20100701

Title: 5-HT3 receptor-dependent modulation of respiratory burst frequency, regularity, and episodicity in isolated adult turtle brainstems.

Journal: Respiratory physiology & neurobiology 20100630

Title: The influence of ondansetron on the analgesic effect of acetaminophen after laparoscopic hysterectomy.

Journal: Clinical pharmacology and therapeutics 20100601

Title: Nausea and vomiting in advanced cancer.

Journal: The American journal of hospice & palliative care 20100501

Title: Retraction Notice: Clinical Management of Postoperative Vomiting after Strabismus Surgery in Children.

Journal: Current drug safety 20100401

Title: Serotonin reuptake transporter (SERT) plays a critical role in the onset of fructose-induced hepatic steatosis in mice.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20100301

Title: Role of 5-HT2A, 5-HT4 and 5-HT7 receptors in the antigen-induced airway hyperresponsiveness in guinea-pigs.

Journal: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20100201

Title: [Impact of intrathecal morphine on the tolerance of early feeding after cesarean section].

Journal: Annales francaises d'anesthesie et de reanimation 20100201

Title: Optimizing emetic control in children receiving antineoplastic therapy: beyond the guidelines.

Journal: Paediatric drugs 20100101

Title: A comparative study of prophylactic antiemetic treatment in cancer patients receiving radiotherapy.

Journal: Journal of B.U.ON. : official journal of the Balkan Union of Oncology 20100101

Title: A randomised, double-blind, placebo-controlled trial of tropisetron in patients with schizophrenia.

Journal: Annals of general psychiatry 20100101

Title: Changes in characteristics of the specific binding of [3H]LY-278584, a 5-HT3-receptor antagonist, on differentiated NG108-15 cells.

Journal: Journal of pharmacological sciences 20100101

Title: Htr2a Gene and 5-HT(2A) Receptor Expression in the Cerebral Cortex Studied Using Genetically Modified Mice.

Journal: Frontiers in neuroscience 20100101

Title: A review of granisetron, 5-hydroxytryptamine3 receptor antagonists, and other antiemetics.

Journal: American journal of therapeutics 20100101

Title: HPLC, TLC, and first-derivative spectrophotometry stability-indicating methods for the determination of tropisetron in the presence of its acid degradates.

Journal: Journal of AOAC International 20100101

Title: Arylalkylamine-, beta-carboline-, quinolizine- and azecine-derived compounds and their in vitro interaction with the ionotropic 5-HT3 receptor: search for new lead structures.

Journal: Arzneimittel-Forschung 20100101

Title: Efficacy of intra-articular injection of celecoxib in a rabbit model of osteoarthritis.

Journal: International journal of molecular sciences 20100101

Title: Use of granisetron transdermal system in the prevention of chemotherapy-induced nausea and vomiting: a review.

Journal: Cancer management and research 20100101

Title: α7 Nicotinic Receptor Agonists: Potential Therapeutic Drugs for Treatment of Cognitive Impairments in Schizophrenia and Alzheimer's Disease.

Journal: The open medicinal chemistry journal 20100101

Title: Glycine transport inhibitors for the treatment of schizophrenia.

Journal: The open medicinal chemistry journal 20100101

Title: Brain imaging of nicotinic receptors in Alzheimer's disease.

Journal: International journal of Alzheimer's disease 20100101

Title: Acute gastroenteritis: from guidelines to real life.

Journal: Clinical and experimental gastroenterology 20100101

Title: Impact of the 5-HT3 receptor channel system for insulin secretion and interaction of ginger extracts.

Journal: European journal of pharmacology 20091210

Title: Treatment with the 5-HT3 antagonist tropisetron modulates glucose-induced obesity in mice.

Journal: International journal of obesity (2005) 20091201

Title: Receptor occupancy theory-based analysis of interindividual differences in antiemetic effects of 5-HT3 receptor antagonists.

Journal: International journal of clinical oncology 20091201

Title: [Role of serotonin receptors in vascular tone in the pithed rat].

Journal: Archivos de cardiologia de Mexico 20091201

Title: Influence of 5-HT3 receptor subunit genes HTR3A, HTR3B, HTR3C, HTR3D and HTR3E on treatment response to antipsychotics in schizophrenia.

Journal: Pharmacogenetics and genomics 20091101

Title: Structural determinants for interaction of partial agonists with acetylcholine binding protein and neuronal alpha7 nicotinic acetylcholine receptor.

Journal: The EMBO journal 20091007

Title: Liquid chromatography/tandem mass spectrometry method for the quantification of deserpidine in human plasma: Application to a pharmacokinetic study.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20091001

Title: Fibromyalgia and myofascial pain syndrome-a dilemma.

Journal: Indian journal of anaesthesia 20091001

Title: Specific targeting of peripheral serotonin 5-HT(3) receptors. Synthesis, biological investigation, and structure-activity relationships.

Journal: Journal of medicinal chemistry 20090611

Title: Different binding modes of tropeines mediating inhibition and potentiation of alpha1 glycine receptors.

Journal: Journal of neurochemistry 20090601

Title: 5-Hydroxytryptamine Receptor Subtypes and their Modulators with Therapeutic Potentials.

Journal: Journal of clinical medicine research 20090601

Title: Anti-inflammatory effects of 5-HT receptor antagonist, tropisetron on experimental colitis in rats.

Journal: European journal of clinical investigation 20090501

Title: Tropisetron attenuates naloxone-induced place aversion in single-dose morphine-treated rats: role of alpha7 nicotinic receptors.

Journal: European journal of pharmacology 20090501

Title: Determination of tropisetron in human plasma by liquid chromatography-tandem mass spectrometry.

Journal: Journal of pharmaceutical and biomedical analysis 20090405

Title: Novel antagonists of serotonin-4 receptors: synthesis and biological evaluation of pyrrolothienopyrazines.

Journal: Bioorganic & medicinal chemistry 20090315

Title: [Nicotinic acetylcholine receptors are possible therapeutic targets for schizophrenia].

Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20090201

Title: [Postoperative analgesia with fentanyl combined with flurbiprofen axetil following gynecologic surgery for turnor].

Journal: Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20090201

Title: The antiemetic interaction of Delta9-tetrahydrocannabinol when combined with tropisetron or dexamethasone in the least shrew.

Journal: Pharmacology, biochemistry, and behavior 20090101

Title: Retraction Notice: Current Management of Vomiting after Tonsillectomy in Children.

Journal: Current drug safety 20090101

Title: Tropisetron plus subhypnotic propofol infusion is more effective than tropisetron alone for the prevention of vomiting in children after tonsillectomy.

Journal: Anaesthesia and intensive care 20090101

Title: [Therapeutic effect of acupuncture on cisplatin-induced nausea and vomiting].

Journal: Zhongguo zhen jiu = Chinese acupuncture & moxibustion 20090101

Title: Modulation of paracetamol and nefopam antinociception by serotonin 5-HT(3) receptor antagonists in mice.

Journal: Pharmacology 20090101

Title: Fibromyalgia: diagnosis and treatment options.

Journal: Gender medicine 20090101

Title: Management of postoperative nausea and vomiting: focus on palonosetron.

Journal: Therapeutics and clinical risk management 20090101

Title: Pathogenesis of tendinopathies: inflammation or degeneration?

Journal: Arthritis research & therapy 20090101

Title: Novel inhibitors of the calcineurin/NFATc hub - alternatives to CsA and FK506?

Journal: Cell communication and signaling : CCS 20090101

Title: Prevention of acute chemotherapy-induced nausea and vomiting: the role of palonosetron.

Journal: Cancer management and research 20090101

Title: Palonosetron for the prevention of chemotherapy-induced nausea and vomiting: approval and efficacy.

Journal: Cancer management and research 20090101

Title: Excitability of small-diameter trigeminal ganglion neurons by 5-HT is mediated by enhancement of the tetrodotoxin-resistant sodium current due to the activation of 5-HT(4) receptors and/or by the inhibition of the transient potassium current.

Journal: Neuroscience 20081202

Title: Myocardial ischemia-mediated excitatory reflexes: a new function for thromboxane A2?

Journal: American journal of physiology. Heart and circulatory physiology 20081201

Title: [Prophylaxis of chemotherapy-induced vomiting and nausea].

Journal: Magyar onkologia 20081201

Title: Newer treatments for fibromyalgia syndrome.

Journal: Therapeutics and clinical risk management 20081201

Title: New treatment options in the management of fibromyalgia: role of pregabalin.

Journal: Neuropsychiatric disease and treatment 20081201

Title: Effect of two artichoke extracts (36_U and 36_EB) on rat ileum (with respect to bowel syndrome) and the peristaltic threshold.

Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20081101

Title: Long-term depression in the superior cervical ganglion of the rat.

Journal: Brain research 20081009

Title: Broad complex tachycardia and tropisteron.

Journal: European journal of anaesthesiology 20081001

Title: Optimizing prophylactic treatment of migraine: Subtypes and patient matching.

Journal: Therapeutics and clinical risk management 20081001

Title: Airway smooth muscle relaxation induced by 5-HT(2A) receptors: role of Na(+)/K(+)-ATPase pump and Ca(2+)-activated K(+) channels.

Journal: Life sciences 20080912

Title: Antinociceptive activity of Buddleja globosa (matico) in several models of pain.

Journal: Journal of ethnopharmacology 20080902

Title: The acute effect of tropisetron on ECG parameters in cancer patients.

Journal: Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 20080901

Title: Assessing the neuronal serotonergic target-based antidepressant stratagem: impact of in vivo interaction studies and knockout models.

Journal: Current neuropharmacology 20080901

Title: Serotonin mediates PGE2 overexpression through 5-HT2A and 5-HT3 receptor subtypes in serum-free tissue culture of macrophage-like synovial cells.

Journal: Rheumatology international 20080801

Title: Zinc modulation of glycine receptors in acutely isolated rat CA3 neurons.

Journal: Life sciences 20080801

Title: Acetaminophen reinforces descending inhibitory pain pathways.

Journal: Clinical pharmacology and therapeutics 20080701

Title: 5-HT3 receptor antagonist for the treatment of tendinopathy.

Journal: Nature clinical practice. Rheumatology 20080701

Title: Cutaneous adverse drug reactions during chemotherapy: consider non-antineoplastic drugs.

Journal: Contact dermatitis 20080601

Title: 5-HT3 receptor antagonist for the treatment of tendinopathy.

Journal: Nature clinical practice. Rheumatology 20080601

Title: [5-HT1A/1B receptors, alpha2-adrenoceptors and the post-receptor adenylate cyclase activation in the mice brain are involved in the antidepressant-like action of agmatine].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20080501

Title: Quantitative determination of ondansetron in human plasma by enantioselective liquid chromatography-tandem mass spectrometry.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20080315

Title: Downregulated hypothalamic 5-HT3 receptor expression and enhanced 5-HT3 receptor antagonist-mediated improvement in fatigue-like behaviour in cholestatic rats.

Journal: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20080301

Title: Efficacy of tropisetron in patients with advanced non-small-cell lung cancer receiving adjuvant chemotherapy with carboplatin and taxanes.

Journal: European journal of cancer care 20080301

Title: [Fibromyalgia syndrome: new developments in pharmacotherapy].

Journal: Zeitschrift fur Rheumatologie 20080201

Title: Isobolographic analysis of multimodal analgesia in an animal model of visceral acute pain.

Journal: Pharmacology, biochemistry, and behavior 20080201

Title: Pharmacogenetics: data, concepts and tools to improve drug discovery and drug treatment.

Journal: European journal of clinical pharmacology 20080201

Title: Serotonin (5-HT) excites rat masticatory muscle afferent fibers through activation of peripheral 5-HT3 receptors.

Journal: Pain 20080101

Title: Chemotherapy-and cancer-related nausea and vomiting.

Journal: Current oncology (Toronto, Ont.) 20080101

Title: Detrimental effects of tropisetron on permanent ischemic stroke in the rat.

Journal: BMC neuroscience 20080101

Title: [Pharmacokinetic and pharmacodynamic features of palonosetron].

Journal: Tumori 20080101

Title: [Meta-analysis of phase III studies with palonosetron in the prevention of vomiting induced by moderately emetogenic chemotherapy].

Journal: Tumori 20080101

Title: [Palonosetron in the prevention of chemotherapy-induced nausea and vomiting (CINV) in Italy: pharmacologic, clinical and economic aspects].

Journal: Tumori 20080101

Title: A meta-analysis of the efficacy of fibromyalgia treatment according to level of care.

Journal: Arthritis research & therapy 20080101

Title: Retraction Notice: The Benefits and Risks of Different Therapies in Preventing Postoperative Nausea and Vomiting in Patients Undergoing Thyroid Surgery.

Journal: Current drug safety 20080101

Title: Hypersensitivity to intravenous ondansetron: a case report.

Journal: Journal of medical case reports 20080101

Title: Biology and therapy of fibromyalgia. Evidence-based biomarkers for fibromyalgia syndrome.

Journal: Arthritis research & therapy 20080101

Title: [11C]CHIBA-1001 as a novel PET ligand for alpha7 nicotinic receptors in the brain: a PET study in conscious monkeys.

Journal: PloS one 20080101

Title: Prophylactic antiemetic therapy for acute abdominal surgery. A comparative study of droperidol, metoclopramide, tropisetron, granisetron and dexamethasone.

Journal: Revista brasileira de anestesiologia 20080101

Title: Management of fibromyalgia syndrome--an interdisciplinary evidence-based guideline.

Journal: German medical science : GMS e-journal 20080101

Title: Evidence for neuromodulation of enteropathogen invasion in the intestinal mucosa.

Journal: Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 20071201

Title: Palonosetron as an anti-emetic and anti-nausea agent in oncology.

Journal: Therapeutics and clinical risk management 20071201

Title: Acute selective serotonin reuptake inhibitors increase conditioned fear expression: blockade with a 5-HT(2C) receptor antagonist.

Journal: Biological psychiatry 20071115

Title: [Subgroups of fibromyalgia].

Journal: Schmerz (Berlin, Germany) 20071001

Title: Postoperative nausea, vomiting, airway morbidity, and analgesic requirements are lower for the ProSeal laryngeal mask airway than the tracheal tube in females undergoing breast and gynaecological surgery.

Journal: British journal of anaesthesia 20071001

Title: A meta-analysis comparing the efficacy of four 5-HT3-receptor antagonists for acute chemotherapy-induced emesis.

Journal: Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 20070901

Title: 5-HT3 receptor antagonists regulate autonomic cardiac dysfunction in primary fibromyalgia syndrome.

Journal: Rheumatology international 20070901

Title: The classification of fibromyalgia syndrome.

Journal: Rheumatology international 20070901

Title: [Prophylactic effect of tropisetron hydrochloride against nausea and vomiting in patients receiving chemotherapy for hematological malignancies].

Journal: Gan to kagaku ryoho. Cancer & chemotherapy 20070901

Title: Indirect mechanism of histamine-induced nociception in temporomandibular joint of rats.

Journal: Life sciences 20070809

Title: Endogenous serotonin excites striatal cholinergic interneurons via the activation of 5-HT 2C, 5-HT6, and 5-HT7 serotonin receptors: implications for extrapyramidal side effects of serotonin reuptake inhibitors.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20070801

Title: Translating pharmacogenomics: challenges on the road to the clinic.

Journal: PLoS medicine 20070801

Title: [Tropisetron hydrochloride in preventing and treating chemotherapy-induced nausea and vomiting: a phase II, randomized, multicenter, double-blinded, comparative clinical trial].

Journal: Ai zheng = Aizheng = Chinese journal of cancer 20070801

Title: Ondansetron oral disintegrating tablets for the prevention of postoperative vomiting in children undergoing strabismus surgery.

Journal: Therapeutics and clinical risk management 20070801

Title: The reinforcing actions of a serotonin-3 receptor agonist within the ventral tegmental area: evidence for subregional and genetic differences and involvement of dopamine neurons.

Journal: The Journal of pharmacology and experimental therapeutics 20070601

Title: [Prevention and treatment of postoperative nausea and vomiting in children. An evidence-based approach].

Journal: Annales francaises d'anesthesie et de reanimation 20070601

Title: Effects of medullary Raphé stimulation on fictive lung ventilation during development in Rana catesbeiana.

Journal: The Journal of experimental biology 20070601

Title: An overview of the clinical use of ondansetron in preschool age children.

Journal: Therapeutics and clinical risk management 20070601

Title: Postoperative colonic motility after tropisetron and a standardized meal in patients undergoing conventional colorectal surgery.

Journal: International journal of colorectal disease 20070501

Title: Randomized, double-blind trial comparing the antiemetic effect of tropisetron plus metopimazine with tropisetron plus placebo in patients receiving multiple cycles of multiple-day cisplatin-based chemotherapy.

Journal: Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 20070401

Title: 5-HT acts on nociceptive primary afferents through an indirect mechanism to induce hyperalgesia in the subcutaneous tissue.

Journal: Neuroscience 20070316

Title: 5-HT(3) receptors in the central amygdala mediate the modulation of thymus function in rats.

Journal: Sheng li xue bao : [Acta physiologica Sinica] 20070225

Title: Determination of tropisetron in human plasma by high performance liquid chromatographic method with UV detection and its application to a bioequivalence study.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070201

Title: Tropisetron modulation of the glycine receptor: femtomolar potentiation and a molecular determinant of inhibition.

Journal: Journal of neurochemistry 20070201

Title: [A randomized double-blind study of prevention of postoperative nausea and vomiting with ondansetron, tropisetron, or granisetron in patients undergoing general anesthesia].

Journal: Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae 20070201

Title: Opposite effects of presynaptic 5-HT3 receptor activation on spontaneous and action potential-evoked GABA release at hippocampal synapses.

Journal: Journal of neurochemistry 20070101

Title: In vitro pharmacological characterization of mitemcinal (GM-611), the first acid-resistant non-peptide motilin receptor agonist, in smooth muscle of rabbit small intestine.

Journal: Pharmacology 20070101

Title: The efficacy of 5-HT3 receptor antagonists for the prevention of postoperative nausea and vomiting after craniotomy: a meta-analysis.

Journal: Journal of neurosurgical anesthesiology 20070101

Title: Management of postoperative nausea and vomiting in children.

Journal: Paediatric drugs 20070101

Title: Systemic anticancer therapy in gynecological cancer patients with renal dysfunction.

Journal: International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 20070101

Title: The enantiomers of tramadol and its major metabolite inhibit peristalsis in the guinea pig small intestine via differential mechanisms.

Journal: BMC pharmacology 20070101

Title: Acute gastroenteritis in children: role of anti-emetic medication for gastroenteritis-related vomiting.

Journal: Paediatric drugs 20070101

Title: Tropisetron, ondansetron, and granisetron for control of chemotherapy-induced emesis in Turkish cancer patients: a comparison of efficacy, side-effect profile, and cost.

Journal: Cancer investigation 20070101

Title: Prevention of postoperative nausea and vomiting in children following adenotonsillectomy, using tropisetron with or without low-dose dexamethasone.

Journal: Journal of anesthesia 20070101

Title: [Optimization of anesthetic maintenance of a facial dermabrasion operation].

Journal: Anesteziologiia i reanimatologiia 20070101

Title: Phencyclidine-induced cognitive deficits in mice are improved by subsequent subchronic administration of tropisetron: role of alpha7 nicotinic receptors.

Journal: European journal of pharmacology 20061228

Title: Contribution of peripheral 5-HT2A or 5-HT3 receptors to Fos expression in the trigeminal spinal nucleus produced by acute injury to the masseter muscle during persistent temporomandibular joint inflammation in rats.

Journal: Neuroscience 20061201

Title: Pharmacology, pharmacogenetics, and clinical efficacy of 5-hydroxytryptamine type 3 receptor antagonists for postoperative nausea and vomiting.

Journal: Current opinion in anaesthesiology 20061201

Title: A randomized, placebo-controlled trial of a single dose of tropisetron for the prevention of vomiting after strabismus surgery in children.

Journal: The Mount Sinai journal of medicine, New York 20061201

Title: Expression of heteromeric glycine receptor-channels in rat spinal cultures and inhibition by neuroactive steroids.

Journal: Neurochemistry international 20061101

Title: Prophylaxis of postoperative vomiting in children undergoing tonsillectomy: a systematic review and meta-analysis.

Journal: British journal of anaesthesia 20061101

Title: Serotonin increases protective duodenal bicarbonate secretion via enteric ganglia and a 5-HT4-dependent pathway.

Journal: Scandinavian journal of gastroenterology 20061101

Title: Palliative chemotherapy beyond three courses conveys no survival or consistent quality-of-life benefits in advanced non-small-cell lung cancer.

Journal: British journal of cancer 20061023

Title: [5-HT3 receptor antagonist als analgetics in rheumatic diseases].

Journal: Zeitschrift fur Rheumatologie 20061001

Title: Pharmacological profiles of the novel analgesic M58996 in rat models of persistent and neuropathic pain.

Journal: Journal of pharmacological sciences 20061001

Title: Acute treatment with 5-HT3 receptor antagonist, tropisetron, reduces immobility in intact female rats exposed to the forced swim test.

Journal: Pharmacology, biochemistry, and behavior 20061001

Title: Tooth-pulp-evoked rostral spinal trigeminal neuronal excitation is attenuated by the activation of 5-HT3 receptors via GABAergic interneurons in the rat.

Journal: Brain research 20060913

Title: A novel mechanism involved in 5-hydroxytryptamine-induced nociception: the indirect activation of primary afferents.

Journal: Neuroscience 20060901

Title: Increased 5-HT(3)-mediated signalling in pelvic afferent neurons from mice deficient in P2X(2) and/or P2X (3) receptor subunits.

Journal: Purinergic signalling 20060901

Title: Anti-emetic prophylaxis with oral tropisetron and/or dexamethasone.

Journal: European journal of clinical investigation 20060801

Title: Drugs for preventing postoperative nausea and vomiting.

Journal: The Cochrane database of systematic reviews 20060719

Title: Inhibition of the serotonin-induced inward current by dextromethorphan in rat nodose ganglion neurons.

Journal: Brain research 20060630

Title: Effects of dexfenfluramine and 5-HT3 receptor antagonists on stress-induced reinstatement of alcohol seeking in rats.

Journal: Psychopharmacology 20060501

Title: The prevention of emergence agitation with tropisetron or clonidine after sevoflurane anesthesia in small children undergoing adenoidectomy.

Journal: Anesthesia and analgesia 20060501

Title: Meta-analysis of the safety of 5-HT3 antagonists with dexamethasone or droperidol for prevention of PONV.

Journal: The Annals of pharmacotherapy 20060501

Title: Meta-analysis of the use of rescue antiemetics following PONV prophylactic failure with 5-HT3 antagonist/dexamethasone versus single-agent therapies.

Journal: The Annals of pharmacotherapy 20060501

Title: Analgesic effect of acetaminophen in humans: first evidence of a central serotonergic mechanism.

Journal: Clinical pharmacology and therapeutics 20060401

Title: Early vs late intraoperative administration of tropisetron for the prevention of nausea and vomiting in children undergoing tonsillectomy and/or adenoidectomy.

Journal: Paediatric anaesthesia 20060401

Title: Novel neurokinin-1 antagonists as antiemetics for the treatment of chemotherapy-induced emesis.

Journal: Supportive cancer therapy 20060401

Title: Potential vascular alpha1-adrenoceptor blocking properties of an array of 5-HT receptor ligands in the rat.

Journal: European journal of pharmacology 20060327

Title: The effects of the prophylactic tropisetron-propofol combination on postoperative nausea and vomiting in patients undergoing thyroidectomy under desflurane anesthesia.

Journal: The Mount Sinai journal of medicine, New York 20060301

Title: Role of pre-operative dexamethasone as prophylaxis for postoperative nausea and vomiting in laparoscopic surgery.

Journal: Journal of minimal access surgery 20060301

Title: Ondansetron and tropisetron do not prevent intraspinal morphine- and fentanyl-induced pruritus in elective cesarean delivery.

Journal: Acta anaesthesiologica Scandinavica 20060201

Title: [A pilot study: gastric motility and nausea/vomiting in two leukemia children receiving chemotherapy].

Journal: Hu li za zhi The journal of nursing 20060201

Title: Mode of action of gingerols and shogaols on 5-HT3 receptors: binding studies, cation uptake by the receptor channel and contraction of isolated guinea-pig ileum.

Journal: European journal of pharmacology 20060113

Title: Supraventricular tachycardia and ST segment depression after intravenous administration of tropisetron.

Journal: European journal of anaesthesiology 20060101

Title: Luminal hypotonicity increases duodenal mucosal permeability by a mechanism involving 5-hydroxytryptamine.

Journal: Acta physiologica (Oxford, England) 20060101

Title: Fibromyalgia--new concepts of pathogenesis and treatment.

Journal: International journal of immunopathology and pharmacology 20060101

Title: Prophylactic tropisetron versus rescue tropisetron in fractionated radiotherapy to moderate or high emetogenic areas: a prospective randomized open label study in cancer patients.

Journal: Medical oncology (Northwood, London, England) 20060101

Title: Biology and therapy of fibromyalgia. New therapies in fibromyalgia.

Journal: Arthritis research & therapy 20060101

Title: Alteration of serotonin transporter density and activity in fibromyalgia.

Journal: Arthritis research & therapy 20060101

Title: New treatment options using 5-HT3 receptor antagonists in rheumatic diseases.

Journal: Current topics in medicinal chemistry 20060101

Title: Prophylaxis of postoperative nausea and vomiting in patients scheduled for breast surgery.

Journal: Clinical drug investigation 20060101

Title: Systematic review on the recurrence of postoperative nausea and vomiting after a first episode in the recovery room - implications for the treatment of PONV and related clinical trials.

Journal: BMC anesthesiology 20060101

Title: Antinociception: mechanistic studies on the action of MD-354 and clonidine. Part 1. The 5-HT3 component.

Journal: European journal of pharmacology 20051228

Title: Interventions for preventing or treating alcohol hangover: systematic review of randomised controlled trials.

Journal: BMJ (Clinical research ed.) 20051224

Title: Psychosocial stress-induced hypertension results from in vivo expression of long-term potentiation in rat sympathetic ganglia.

Journal: Neurobiology of disease 20051201

Title: Association of the ABCB1 3435C>T polymorphism with antiemetic efficacy of 5-hydroxytryptamine type 3 antagonists.

Journal: Clinical pharmacology and therapeutics 20051201

Title: Contribution of the peripheral 5-HT 2A receptor to mechanical hyperalgesia in a rat model of neuropathic pain.

Journal: Neurochemistry international 20051101

Title: Tropisetron improves deficient inhibitory auditory processing in DBA/2 mice: role of alpha 7 nicotinic acetylcholine receptors.

Journal: Psychopharmacology 20051101

Title: Employment of substandard antiemetic prophylaxis in recent trials of chemotherapy-induced nausea and vomiting.

Journal: The Annals of pharmacotherapy 20051101

Title: A nonneuronal 5-hydroxytryptamine receptor 3 induces chloride secretion in the rat distal colonic mucosa.

Journal: American journal of surgery 20051101

Title: Cytochrome P450 2D6 metabolism and 5-hydroxytryptamine type 3 receptor antagonists for postoperative nausea and vomiting.

Journal: Medical science monitor : international medical journal of experimental and clinical research 20051001

Title: Mediation of neurogenic ion transport by acetylcholine, prostanoids and 5-hydroxytryptamine in porcine ileum.

Journal: European journal of pharmacology 20050920

Title: Serotonergic mechanisms influence the response to glucocorticoid treatment in TMJ arthritis.

Journal: Mediators of inflammation 20050831

Title: The 5-HT3 receptor antagonist tropisetron inhibits T cell activation by targeting the calcineurin pathway.

Journal: Biochemical pharmacology 20050801

Title: [Preventive efficacies of china-made tropisetron hydrochloride and Navoban on chemotherapy-induced nausea and vomiting: a randomized controlled clinical trial].

Journal: Ai zheng = Aizheng = Chinese journal of cancer 20050801

Title: 5HT3-receptor antagonists as antiemetics in cancer.

Journal: Drug and therapeutics bulletin 20050801

Title: Update on anti-emetics for chemotherapy-induced emesis.

Journal: Internal medicine journal 20050801

Title: Pharmacokinetically guided phase I trial of topotecan and etoposide phosphate in recurrent ovarian cancer.

Journal: British journal of cancer 20050711

Title: Tropisetron: optimal dosage for children in prevention of chemotherapy-induced vomiting.

Journal: Pediatric blood & cancer 20050701

Title: Tropisetron improves deficits in auditory P50 suppression in schizophrenia.

Journal: Schizophrenia research 20050701

Title: The antiemetic effect of a novel tropisetron patch in anticancer agents-induced kaolin pica model using rats.

Journal: Environmental toxicology and pharmacology 20050701

Title: Serotonin excites neurons in the human submucous plexus via 5-HT3 receptors.

Journal: Gastroenterology 20050501

Title: Autonomic efferents affect intake of imbalanced amino acid diets by rats.

Journal: Pharmacology, biochemistry, and behavior 20050501

Title: Molecular dissection of tropisetron, an alpha7 nicotinic acetylcholine receptor-selective partial agonist.

Journal: Neuroscience letters 20050422

Title: Intracranial self-administration of cocaine within the posterior ventral tegmental area of Wistar rats: evidence for involvement of serotonin-3 receptors and dopamine neurons.

Journal: The Journal of pharmacology and experimental therapeutics 20050401

Title: Bradykinin potentiates 5-HT3 receptor-mediated current in rat trigeminal ganglion neurons.

Journal: Acta pharmacologica Sinica 20050401

Title: Analgesic activity of 5-HT3 receptor antagonists.

Journal: Bulletin of experimental biology and medicine 20050401

Title: Involvement of c-Src and protein kinase C delta in the inhibition of Cl(-)/OH- exchange activity in Caco-2 cells by serotonin.

Journal: The Journal of biological chemistry 20050325

Title: Tooth-pulp-evoked rostral spinal trigeminal nucleus neuron activity is inhibited by conditioning sciatic nerve stimulation in the rat: possible role of 5-HT3 receptor mediated GABAergic inhibition.

Journal: Brain research bulletin 20050215

Title: Regional heterogeneity for the intracranial self-administration of ethanol and acetaldehyde within the ventral tegmental area of alcohol-preferring (P) rats: involvement of dopamine and serotonin.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20050201

Title: Acute emesis: moderately emetogenic chemotherapy.

Journal: Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 20050201

Title: 3,4 Methylenedioxymethamphetamine-induced conditioned place preference (CPP) is mediated by endocannabinoid system.

Journal: Pharmacological research 20050201

Title: Serotonin type 3 receptors stimulate offensive aggression in Syrian hamsters.

Journal: Behavioural brain research 20050106

Title: Peristalsis in the Guinea pig small intestine in vitro is impaired by acetaminophen but not aspirin and dipyrone.

Journal: Anesthesia and analgesia 20050101

Title: Granisetron versus tropisetron for prophylaxis of acute chemotherapy-induced emesis: a pooled analysis.

Journal: Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 20050101

Title: Selective serotonin 5-HT3 receptor antagonists for postoperative nausea and vomiting: are they all the same?

Journal: CNS drugs 20050101

Title: Central serotonin 3 receptors play an important role in the modulation of nociceptive neural activity of trigeminal subnucleus caudalis and nocifensive orofacial behavior in rats with persistent temporomandibular joint inflammation.

Journal: Neuroscience 20050101

Title: Stimulation of the lateral hypothalamus produces antinociception mediated by 5-HT1A, 5-HT1B and 5-HT3 receptors in the rat spinal cord dorsal horn.

Journal: Neuroscience 20050101

Title: The utility of antiemetics in the prevention and treatment of postoperative nausea and vomiting in patients scheduled for laparoscopic cholecystectomy.

Journal: Current pharmaceutical design 20050101

Title: In vivo excitation of GABA interneurons in the medial prefrontal cortex through 5-HT3 receptors.

Journal: Cerebral cortex (New York, N.Y. : 1991) 20041201

Title: The role of 5-hydroxytryptamine3 receptors in the vagal afferent activation-induced inhibition of the first cervical dorsal horn spinal neurons projected from tooth pulp in the rat.

Journal: The Journal of pharmacology and experimental therapeutics 20041101

Title: Potentiation of 5-HT3 receptor function by the activation of coexistent 5-HT2 receptors in trigeminal ganglion neurons of rats.

Journal: Neuropharmacology 20041101

Title: 5-HT3 receptor antagonists for prevention of late acute-onset emesis.

Journal: The Annals of pharmacotherapy 20041001

Title: Serotonin type 3 receptors modulate the aggression-stimulating effects of adolescent cocaine exposure in Syrian hamsters (Mesocricetus auratus).

Journal: Behavioral neuroscience 20041001

Title: Activation of presynaptic 5-HT3 receptors facilitates glutamatergic synaptic inputs to area postrema neurons in rat brain slices.

Journal: Methods and findings in experimental and clinical pharmacology 20041001

Title: Blockade of peripheral 5HT3 receptor attenuates the formalin-induced nocifensive behavior in persistent temporomandibular joint inflammation of rat.

Journal: Neuroscience letters 20040902

Title: Acetaminophen: a central analgesic drug that involves a spinal tropisetron-sensitive, non-5-HT(3) receptor-mediated effect.

Journal: Molecular pharmacology 20040901

Title: Tamoxifen treatment reverses the adverse effects of chemotherapy-induced ovarian failure on serum lipids.

Journal: British journal of cancer 20040802

Title: [Serotonin and anticancer drug-induced emesis].

Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20040801

Title: Cloning, pharmacological characterisation and tissue distribution of a novel 5-HT4 receptor splice variant, 5-HT4(i).

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20040601

Title: Dilatation induced by 5-HT in the middle meningeal artery of the anaesthetised cat.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20040601

Title: Pegylated liposomal doxorubicin in combination with mitomycin C, infusional 5-fluorouracil and sodium folinic acid. A phase-I-study in patients with upper gastrointestinal cancer.

Journal: British journal of cancer 20040517

Title: 5-HT3 antagonist ICS 205-930 enhances naltrexone's effects on ethanol intake.

Journal: European journal of pharmacology 20040503

Title: 5-HT receptors involved in opioid-activated descending inhibition of spinal withdrawal reflexes in the decerebrated rabbit.

Journal: Pain 20040501

Title: Antipruritic effects of two different 5-HT3 receptor antagonists and an antihistamine in haemodialysis patients.

Journal: Experimental dermatology 20040501

Title: Activity of alpha7-selective agonists at nicotinic and serotonin 5HT3 receptors expressed in Xenopus oocytes.

Journal: Bioorganic & medicinal chemistry letters 20040419

Title: [Tropisetron in attenuation of nausea and vomiting in patients undergoing high-dose chemo-radiotherapy supported by autologous peripheral blood stem cell transplantation].

Journal: Ai zheng = Aizheng = Chinese journal of cancer 20040401

Title: Patterns of serotonin- and 2-methylserotonin-induced pain may reflect 5-HT3 receptor sensitization.

Journal: European journal of pharmacology 20040112

Title: Efficacy and tolerability of intravenous tropisetron in the treatment of fibromyalgia.

Journal: Scandinavian journal of rheumatology 20040101

Title: Same old story? Do we need to modify our supportive care treatment of elderly cancer patients? Focus on antiemetics.

Journal: Drugs & aging 20040101

Title: Expression of 5-HT3A receptors in cells of the immune system.

Journal: Scandinavian journal of rheumatology. Supplement 20040101

Title: Spectrum of use and tolerability of 5-HT3 receptor antagonists.

Journal: Scandinavian journal of rheumatology. Supplement 20040101

Title: Analgesic effects of 5-HT3 receptor antagonists.

Journal: Scandinavian journal of rheumatology. Supplement 20040101

Title: The influence of the 5-HT3 receptor antagonist tropisetron on pain in fibromyalgia: a functional magnetic resonance imaging pilot study.

Journal: Scandinavian journal of rheumatology. Supplement 20040101

Title: Antiinflammatory effects of 5-HT3 receptor antagonists in lipopolysaccharide-stimulated primary human monocytes.

Journal: Scandinavian journal of rheumatology. Supplement 20040101

Title: Tropisetron inhibits serotonin-induced PGE2 release from macrophage-like synovial cells in serum-free tissue culture.

Journal: Scandinavian journal of rheumatology. Supplement 20040101

Title: Immunomodulatory function of the 5-HT3 receptor antagonist tropisetron.

Journal: Scandinavian journal of rheumatology. Supplement 20040101

Title: Influence of tropisetron on the serum substance P levels in fibromyalgia patients.

Journal: Scandinavian journal of rheumatology. Supplement 20040101

Title: Local treatment of tendinopathies and myofascial pain syndromes with the 5-HT3 receptor antagonist tropisetron.

Journal: Scandinavian journal of rheumatology. Supplement 20040101

Title: Trigger point injection treatment with the 5-HT3 receptor antagonist tropisetron in patients with late whiplash-associated disorder. First results of a multiple case study.

Journal: Scandinavian journal of rheumatology. Supplement 20040101

Title: Intra-articular treatment of arthritides and activated osteoarthritis with the 5-HT3 receptor antagonist tropisetron. A double-blind study compared with methylprednisolone.

Journal: Scandinavian journal of rheumatology. Supplement 20040101

Title: Serotonin type 3 receptor antagonist tropisetron in the treatment of chronic inflammatory rheumatic conditions--preliminary clinical experience.

Journal: Scandinavian journal of rheumatology. Supplement 20040101

Title: Treatment of systemic sclerosis with the 5-HT3 receptor antagonist tropisetron.

Journal: Scandinavian journal of rheumatology. Supplement 20040101

Title: Treatment of fibromyalgia with tropisetron--dose and efficacy correlations.

Journal: Scandinavian journal of rheumatology. Supplement 20040101

Title: The assessment of vegetative and functional symptoms in fibromyalgia patients: the tropisetron experience.

Journal: Scandinavian journal of rheumatology. Supplement 20040101

Title: Intravenous treatment of fibromyalgia with the 5-HT3 receptor antagonist tropisetron in a rheumatological practice.

Journal: Scandinavian journal of rheumatology. Supplement 20040101

Title: Treatment of chronic low back pain with tropisetron.

Journal: Scandinavian journal of rheumatology. Supplement 20040101

Title: Calcium influx through presynaptic 5-HT3 receptors facilitates GABA release in the hippocampus: in vitro slice and synaptosome studies.

Journal: Neuroscience 20040101

Title: 5-HT3 receptor antagonists: a new therapeutic approach in rheumatology? Proceedings of a symposium. Frankfurt, Germany, February 12-13, 2004.

Journal: Scandinavian journal of rheumatology. Supplement 20040101

Title: Participation of the serotonin system in rofecoxib-induced antinociception.

Journal: Proceedings of the Western Pharmacology Society 20040101

Title: [What's new in the therapy of fibromyalgia?].

Journal: Schmerz (Berlin, Germany) 20031201

Title: Use of anti-emetics after intragastric balloon placement: experience with three different drug treatments.

Journal: Obesity surgery 20031201

Title: Pharmacological profile of the 5-HT-induced inhibition of cardioaccelerator sympathetic outflow in pithed rats: correlation with 5-HT1 and putative 5-ht5A/5B receptors.

Journal: British journal of pharmacology 20031001

Title: Pharmacoeconomic considerations of tropisetron for prophylaxis and treatment of CINV and PONV.

Journal: Expert review of pharmacoeconomics & outcomes research 20031001

Title: Cost-minimisation analysis of pegylated liposomal doxorubicin hydrochloride versus topotecan in the treatment of patients with recurrent epithelial ovarian cancer in Spain.

Journal: British journal of cancer 20030915

Title: The tricyclic antidepressant clomipramine increases plasma glucose levels of mice.

Journal: Journal of pharmacological sciences 20030901

Title: Involvement of 5-HT(2) receptor in imipramine-induced hyperglycemia in mice.

Journal: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20030901

Title: Tropisetron and dexamethasone administered twice daily for the prevention of acute emesis in patients treated with continuous infusion of Cisplatin-Doxorubicin and high-dose Ifosfamide over 48, 24, and 120 hours.

Journal: Cancer nursing 20030801

Title: [Tolerance induction in anaphylaxis to carboplatin].

Journal: Deutsche medizinische Wochenschrift (1946) 20030725

Title: Benzodiazepines block alpha2-containing inhibitory glycine receptors in embryonic mouse hippocampal neurons.

Journal: Journal of neurophysiology 20030701

Title: Current position of 5HT3 antagonists and the additional value of NK1 antagonists; a new class of antiemetics.

Journal: British journal of cancer 20030616

Title: Dopaminergic excitation of the goat carotid body is mediated by the serotonin type 3 receptor subtype.

Journal: Respiratory physiology & neurobiology 20030612

Title: Effect of the CYP2D6 genotype on the pharmacokinetics of tropisetron in healthy Korean subjects.

Journal: European journal of clinical pharmacology 20030601

Title: Variations in the 5-hydroxytryptamine type 3B receptor gene as predictors of the efficacy of antiemetic treatment in cancer patients.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20030601

Title: [Local treatment of rheumatic diseases with the 5-HT3 receptor antagonist tropisetron].

Journal: Schmerz (Berlin, Germany) 20030601

Title: Cost-effectiveness of antiemetics use during cancer chemotherapy.

Journal: Expert review of pharmacoeconomics & outcomes research 20030601

Title: Direct interaction of serotonin type 3 receptor ligands with recombinant and native alpha 9 alpha 10-containing nicotinic cholinergic receptors.

Journal: Molecular pharmacology 20030501

Title: Phoneutria nigriventer spider venom activates 5-HT4 receptors in rat-isolated vagus nerve.

Journal: British journal of pharmacology 20030501

Title: 5-HT3 receptors partially mediate halothane depression of spinal dorsal horn sensory neurons.

Journal: Anesthesia and analgesia 20030401

Title: Randomized, double-blinded comparison of tropisetron and placebo for prevention of postoperative nausea and vomiting after supratentorial craniotomy.

Journal: Journal of neurosurgical anesthesiology 20030401

Title: Expression of 5-HT3 receptors by extrinsic duodenal afferents contribute to intestinal inhibition of gastric emptying.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20030301

Title: Role of serotonin in thromboxane A2-induced coronary chemoreflex.

Journal: American journal of physiology. Heart and circulatory physiology 20030301

Title: Heterogeneous actions of serotonin on interneurons in rat visual cortex.

Journal: Journal of neurophysiology 20030301

Title: Pharmacologic characterization of contractile serotonergic receptors in human isolated mesenteric artery.

Journal: Journal of cardiovascular pharmacology 20030201

Title: Plasma serotonin and histamine levels in hemodialysis-related pruritus are not significantly influenced by 5-HT3 receptor blocker and antihistaminic therapy.

Journal: Clinical nephrology 20030201

Title: [5-HT3-receptor-antagonists in therapy of rheumatic diseases].

Journal: Zeitschrift fur Rheumatologie 20030201

Title: [The influence of depression on the effect of Tropisetron in the therapy of fibromyalgia].

Journal: Zeitschrift fur Rheumatologie 20030201

Title: The efficacy and cost-effectiveness of prophylactic 5-hydroxytryptamine3 receptor antagonists: tropisetron, ondansetron and dolasetron.

Journal: Anaesthesia and intensive care 20030201

Title: 5-HT4 receptor ligands: applications and new prospects.

Journal: Journal of medicinal chemistry 20030130

Title: Effects of serotonin-3 receptor antagonists on the intracranial self-administration of ethanol within the ventral tegmental area of Wistar rats.

Journal: Psychopharmacology 20030101

Title: Further evidence that the discriminative stimulus properties of indorenate are mediated by 5-HT 1A/1B/2C receptors.

Journal: Pharmacology, biochemistry, and behavior 20030101

Title: Benefits and risks of newer treatments for chemotherapy-induced and postoperative nausea and vomiting.

Journal: Drug safety 20030101

Title: [Neurotransmitter mechanism of the tropoxin effect in comparison with other antimigraine preparations].

Journal: Eksperimental'naia i klinicheskaia farmakologiia 20030101

Title: Do cytochrome enzymes influence the therapeutic effect of tropisetron in fibromyalgia?

Journal: Drugs under experimental and clinical research 20030101

Title: Comparison of the antiemetic efficacy of tropisetron and droperidol with patient-given tramadol.

Journal: The Journal of international medical research 20030101

Title: Impact of nausea and vomiting on quality of life in cancer patients during chemotherapy.

Journal: Health and quality of life outcomes 20030101

Title: Binding interactions of antagonists with 5-hydroxytryptamine3A receptor models.

Journal: Journal of receptor and signal transduction research 20030101

Title: Inhibitory interactions between 5-HT3 and P2X channels in submucosal neurons.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20021201

Title: Evidence for the involvement of spinal cord alpha1 adrenoceptors in nitrous oxide-induced antinociceptive effects in Fischer rats.

Journal: Anesthesiology 20021201

Title: Dual cooperative allosteric modulation of binding to ionotropic glycine receptors.

Journal: Neuropharmacology 20021201

Title: Activated platelets contribute to stimulation of cardiac afferents during ischaemia in cats: role of 5-HT(3) receptors.

Journal: The Journal of physiology 20021101

Title: Treatment of tendopathies with tropisetron.

Journal: Rheumatology international 20021101

Title: Impact of a multimodal anti-emetic prophylaxis on patient satisfaction in high-risk patients for postoperative nausea and vomiting.

Journal: Anaesthesia 20021001

Title: [Tropisetron for prevention of postoperative nausea and vomiting: a quantitative systematic review].

Journal: Der Anaesthesist 20021001

Title: 5-HT3 receptors mediate serotonergic fast synaptic excitation of neocortical vasoactive intestinal peptide/cholecystokinin interneurons.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20020901

Title: Xanthine oxidase, but not neutrophils, contributes to activation of cardiac sympathetic afferents during myocardial ischaemia in cats.

Journal: The Journal of physiology 20020815

Title: Concurrent administration of Docetaxel and Stealth liposomal doxorubicin with radiotherapy in non-small cell lung cancer : excellent tolerance using subcutaneous amifostine for cytoprotection.

Journal: British journal of cancer 20020812

Title: The effects of continuous 5-HT(3) receptor antagonist administration on the subsequent behavioral response to cocaine.

Journal: European journal of pharmacology 20020809

Title: Small-dose dexamethasone reduces nausea and vomiting after laparoscopic cholecystectomy: a comparison of tropisetron with saline.

Journal: Anesthesia and analgesia 20020701

Title: Tropisetron vs ondansetron for prevention of postoperative nausea and vomiting after laparoscopic cholecystectomy: a randomized double-blind, placebo-controlled study.

Journal: Surgical endoscopy 20020701

Title: Patient-tailored antiemetic treatment with 5-hydroxytryptamine type 3 receptor antagonists according to cytochrome P-450 2D6 genotypes.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20020615

Title: 5-HT(3) receptors mediate inflammation-induced unmasking of functional tachykinin responses in vitro.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20020601

Title: 5-HT(4) receptor antagonists: structure-affinity relationships and ligand-receptor interactions.

Journal: Current topics in medicinal chemistry 20020601

Title: [Pharmacoeconomical model for cost calculation using a study on prophylaxis of nausea and vomiting in the postoperative phase as an example. Cost effectiveness analysis of a tropisetron supplemented desflurane anaesthesia in comparison to a propofol total intravenous anaesthesia (TIVA)].

Journal: Der Anaesthesist 20020601

Title: Paracetamol exerts a spinal, tropisetron-reversible, antinociceptive effect in an inflammatory pain model in rats.

Journal: European journal of pharmacology 20020517

Title: Intrathecal administration of 5-HT(3) receptor agonist modulates jaw muscle activity evoked by injection of mustard oil into the temporomandibular joint in the rat.

Journal: Brain research 20020503

Title: Simultaneous determination of ondansetron and tropisetron in human plasma using HPLC with UV detection.

Journal: Biomedical chromatography : BMC 20020501

Title: Serotonin 5-HT(3) receptors on mechanosensitive neurons with cardiac afferents.

Journal: American journal of physiology. Heart and circulatory physiology 20020501

Title: Oral ondansetron, tropisetron or metoclopramide to prevent postoperative nausea and vomiting: a comparison in high-risk patients undergoing thyroid or parathyroid surgery.

Journal: Acta anaesthesiologica Scandinavica 20020501

Title: [Pilot study with 5-HT3 antagonists. Good outcome in fibromyalgia pain].

Journal: MMW Fortschritte der Medizin 20020314

Title: The prophylactic effect of tropisetron on epidural morphine-related nausea and vomiting: a comparison of dexamethasone with saline.

Journal: Anesthesia and analgesia 20020301

Title: Drug-induced extrapyramidal reactions.

Journal: Journal of paediatrics and child health 20020201

Title: 5-Hydroxytryptamine mediated contractions in isolated preparations of equine ileum and pelvic flexure: pharmacological characterization of a new 5-HT(4) agonist.

Journal: Journal of veterinary pharmacology and therapeutics 20020201

Title: [Dexamethasone enhances the effect of tropisetron and ondansetron against nausea and vomiting against nausea and vomiting after patient-controlled analgesia].

Journal: Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 20020201

Title: Ramosetron, a 5-HT3 receptor antagonist for the control of nausea and vomiting.

Journal: Drugs of today (Barcelona, Spain : 1998) 20020201

Title: Synthesis and pharmacology of isoquinuclidine derivatives as 5-HT(3) ligands.

Journal: Bioorganic & medicinal chemistry letters 20020121

Title: Infusional 5-fluorouracil, cisplatin and mitomycin C in advanced gastric cancer: a low cost effective regimen.

Journal: British journal of cancer 20020121

Title: Safe administration of etoposide phosphate after hypersensitivity reaction to intravenous etoposide.

Journal: British journal of cancer 20020107

Title: Acute effects of serotonin on rat bladder contractility.

Journal: Urologia internationalis 20020101

Title: Does intravenous ondansetron affect gastric emptying of a solid meal, gastric electrical activity or blood hormone levels in healthy volunteers?

Journal: Alimentary pharmacology & therapeutics 20020101

Title: [Local treatment of periarthropathies with the 5-HT3-receptor-antagonist tropisetron].

Journal: Zeitschrift fur Orthopadie und ihre Grenzgebiete 20020101

Title: Low-dose dexamethasone reduces nausea and vomiting after tympanomastoid surgery: a comparison of tropisetron with saline.

Journal: American journal of otolaryngology 20020101

Title: 5-HT3-receptor antagonists and the cytochrome P450 system: clinical implications.

Journal: Cancer journal (Sudbury, Mass.) 20020101

Title: Local treatment of tendinopathies: a comparison between tropisetron and depot corticosteroids combined with local anesthetics.

Journal: Scandinavian journal of rheumatology 20020101

Title: [Prevention of postoperative nausea and vomiting with highly selective 5-HT3 serotonin receptors antagonists during different types of surgery].

Journal: Anesteziologiia i reanimatologiia 20020101

Title: [Pain modification by the 5-HT3 receptor antagonist tropisetron in secondary fibromyalgias].

Journal: Fortschritte der Medizin. Originalien 20020101

Title: Pharmacokinetics of therapeutic doses of tropisetron in healthy volunteers.

Journal: British journal of clinical pharmacology 20011201

Title: Association between increased 5-HIAA plasma concentrations and postoperative nausea and vomiting in patients undergoing general anaesthesia for surgery.

Journal: European journal of anaesthesiology 20011201

Title: Inhibition of ganglionic long-term potentiation decreases blood pressure in spontaneously hypertensive rats.

Journal: Experimental biology and medicine (Maywood, N.J.) 20011201

Title: Comparative study of tropisetron with the addition of dexamethasone or alprazolam in breast cancer patients receiving adjuvant chemotherapy with CEF (cyclophosphamide, epirubicin and 5-fluorouracil).

Journal: Journal of chemotherapy (Florence, Italy) 20011201

Title: Potent antagonism of 5-HT(3) and 5-HT(6) receptors by olanzapine.

Journal: European journal of pharmacology 20011102

Title: Neuroepithelial bodies in mammalian lung express functional serotonin type 3 receptor.

Journal: American journal of physiology. Lung cellular and molecular physiology 20011001

Title: Prevention of postoperative nausea and vomiting after laparoscopic gynaecological surgery. Combined antiemetic treatment with tropisetron and metoclopramide vs. metoclopramide alone.

Journal: European journal of anaesthesiology 20010901

Title: Comparison of tropisetron and granisetron in the control of nausea and vomiting in children receiving combined cancer chemotherapy.

Journal: Pediatric hematology and oncology 20010901

Title: [Presynaptic 5-hydroxytryptamine receptors enhance cholinergic neurosecretion in the human iris-ciliary body].

Journal: [Zhonghua yan ke za zhi] Chinese journal of ophthalmology 20010901

Title: Concealed post-tonsillectomy haemorrhage associated with the use of the antiemetic tropisetron.

Journal: Anaesthesia and intensive care 20010801

Title: Reversal of neuroleptic-induced orofacial dyskinesia by 5-HT3 receptor antagonists.

Journal: European journal of pharmacology 20010525

Title: Characterization of discriminative stimulus effects of the neuroactive steroid pregnanolone.

Journal: The Journal of pharmacology and experimental therapeutics 20010501

Title: Influence of serotonin receptor antagonists on substance P and serotonin release evoked by tooth pulp stimulation with electro-acupuncture in the trigeminal nucleus cudalis of the rabbit.

Journal: Neuroscience research 20010501

Title: Ramosetron for the management of chemotherapy-induced gastrointestinal events in patients with hematological malignancies.

Journal: Methods and findings in experimental and clinical pharmacology 20010501

Title: [The clinical effect of Tropisetron in the prevention of nausea and vomiting induced by anti-cancer drugs].

Journal: Zhonghua zhong liu za zhi [Chinese journal of oncology] 20010501

Title: An endogenous 5-HT(7) receptor mediates pigment granule dispersion in Xenopus laevis melanophores.

Journal: British journal of pharmacology 20010401

Title: Systemic vascular effects of thrombin and thrombin receptor activating peptide in rats.

Journal: Thrombosis research 20010315

Title: Relaxation induced by serotonin and sumatriptan in isolated guinea pig gallbladder strips.

Journal: Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie 20010301

Title: The 5-HT3 antagonist tropisetron (ICS 205-930) is a potent and selective alpha7 nicotinic receptor partial agonist.

Journal: Bioorganic & medicinal chemistry letters 20010212

Title: Intestinal serotonin acts as a paracrine substance to mediate vagal signal transmission evoked by luminal factors in the rat.

Journal: The Journal of physiology 20010201

Title: 5HT4(a) and 5-HT4(b) receptors have nearly identical pharmacology and are both expressed in human atrium and ventricle.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20010201

Title: [5-HT3 receptor antagonists as a new therapeutic principle in rheumatology?].

Journal: Zeitschrift fur Rheumatologie 20010201

Title: Mechanisms for contractile effect of Dai-kenchu-to in isolated guinea pig ileum.

Journal: Digestive diseases and sciences 20010201

Title: The major role of peripheral release of histamine and 5-hydroxytryptamine in formalin-induced nociception.

Journal: Neuroscience 20010101

Title: Possible involvement of 5-HT4 receptors, in addition to 5-HT3 receptors, in the emesis induced by high-dose cisplatin in Suncus murinus.

Journal: Japanese journal of pharmacology 20010101

Title: 5-HT 3 receptor antagonist ICS 205-930 alters the discriminative effects of ethanol.

Journal: Pharmacology, biochemistry, and behavior 20010101

Title: Fibromyalgia treatment with intravenous tropisetron administration.

Journal: Drugs under experimental and clinical research 20010101

Title: Short-term treatment of primary fibromyalgia with the 5-HT3-receptor antagonist tropisetron. Results of a randomized, double-blind, placebo-controlled multicenter trial in 418 patients.

Journal: International journal of clinical pharmacology research 20010101

Title: Comparison of the efficacy of 2 mg versus 5 mg tropisetron in the management of post-operative nausea and vomiting.

Journal: The Journal of international medical research 20010101

Title: Prevention of delayed emesis induced by moderately emetogenic chemotherapy in patients with acute emesis: a pilot study with ACTH-Depot plus tropisetron.

Journal: Medical oncology (Northwood, London, England) 20010101

Title: The development of a protocol for the use of 5-HT3 antagonists in chemotherapy-induced nausea and vomiting.

Journal: Clinical oncology (Royal College of Radiologists (Great Britain)) 20010101

Title: Glycine receptor beta subunits play a critical role in potentiation of glycine responses by ICS-205,930.

Journal: Molecular pharmacology 20001001

Title: Cloning, expression, and characterization of ferret 5-HT(3) receptor subunit.

Journal: European journal of pharmacology 20000707

Title: Selective blocking effects of tropisetron and atropine on recombinant glycine receptors.

Journal: Journal of neurochemistry 19990801

Title: The anti-emetic efficacy of tropisetron plus dexamethasone in patients treated with high-dose chemotherapy and stem cell transplantation.

Journal: Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 19990301

Title: Tropisetron in the prevention of acute nausea and vomiting in patients treated with high dose epirubicin.

Journal: Journal of experimental & clinical cancer research : CR 19980301

Title: Molecular cloning, functional expression, and pharmacological characterization of 5-hydroxytryptamine3 receptor cDNA and its splice variants from guinea pig.

Journal: Molecular pharmacology 19980201

Title: Navoban (tropisetron, ICS 205-930) and dexamethasone combination in the prevention of vomiting for patients receiving preconditioning high-dose chemotherapy before marrow transplantation.

Journal: Japanese journal of clinical oncology 19980201

Title: Cloning and expression of a human serotonin 5-HT4 receptor cDNA.

Journal: Journal of neurochemistry 19971101

Title: Cloning, expression and pharmacology of the mouse 5-HT(4L) receptor.

Journal: FEBS letters 19961125

Title: [3H]5-hydroxytryptamine labels the agonist high affinity state of the cloned rat 5-HT4 receptor.

Journal: European journal of pharmacology 19960523

Title: Binding affinity of sarpogrelate, a new antiplatelet agent, and its metabolite for serotonin receptor subtypes.

Journal: Archives internationales de pharmacodynamie et de therapie 19960101

Title: Molecular cloning of human 5-hydroxytryptamine3 receptor: heterogeneity in distribution and function among species.

Journal: Molecular pharmacology 19950901

Title: The 5-HT4 receptor: molecular cloning and pharmacological characterization of two splice variants.

Journal: The EMBO journal 19950615

Title: 5HT3 receptor antagonists do not block nicotine induced hyperactivity in rats.

Journal: Psychopharmacology 19950501

Title: Prevention of emesis by tropisetron (Navoban) in children receiving cytotoxic therapy for solid malignancies.

Journal: Seminars in oncology 19941001

Title: Enhancement of memory retrieval and attenuation of scopolamine-induced amnesia following administration of 5-HT3 antagonist ICS 205-930.

Journal: Pharmacology & toxicology 19910801

Title: Peristalsis evoked by 5-HT and renzapride: evidence for putative 5-HT4 receptor activation.

Journal: British journal of pharmacology 19910301

Title: The effect of serotonergic agents on haloperidol-induced catalepsy.

Journal: Life sciences 19900101

Title: Macor JE, et al. The 5-HT3 antagonist tropisetron (ICS 205-930) is a potent and selective alpha7 nicotinic receptor partial agonist.Bioorg Med Chem Lett. 2001 Feb 12;11(3):319-21.

Title: Vega Lde L, et al. The 5-HT3 receptor antagonist tropisetron inhibits T cell activation by targeting the calcineurin pathway. Biochem Pharmacol. 2005 Aug 1;70(3):369-80.

Title: Stratz C, et al. The anti-inflammatory effects of the 5-HT? receptor antagonist tropisetron are mediated by the inhibition of p38 MAPK activation in primary human monocytes. Int Immunopharmacol. 2012 Aug;13(4):398-402.

Title: Candelario-Jalil E, et al. Detrimental effects of tropisetron on permanent ischemic stroke in the rat. BMC Neurosci. 2008 Feb 6;9:19.

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Tags:89565-68-4 Molecular Formula|89565-68-4 MDL|89565-68-4 SMILES|89565-68-4 Tropisetron