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926908-04-5,MFCD10568146
Catalog No.:AA0036NG

926908-04-5 | N-Hydroxy-7-(naphthalen-2-ylthio)heptanamide

Pack Size
Purity
Availability
Price(USD)
Quantity
  
5mg
≥98%
in stock  
$122.00   $85.00
- +
10mg
≥98%
in stock  
$226.00   $158.00
- +
25mg
≥98%
in stock  
$535.00   $374.00
- +
  • Technical Information
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  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA0036NG
Chemical Name:
N-Hydroxy-7-(naphthalen-2-ylthio)heptanamide
CAS Number:
926908-04-5
Molecular Formula:
C17H21NO2S
Molecular Weight:
303.4191
MDL Number:
MFCD10568146
SMILES:
ONC(=O)CCCCCCSc1ccc2c(c1)cccc2
Properties
Properties
 
Form:
Solid  
Stability:
Light Sensitive  
Storage:
Inert atmosphere;2-8℃;  

Computed Properties
 
Complexity:
311  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
21  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
8  
XLogP3:
4.1  

Literature

Title: A new histone deacetylase inhibitor improves liver fibrosis in BDL rats through suppression of hepatic stellate cells.

Journal: British journal of pharmacology 20141101

Title: Potential anti-cancer activity of N-hydroxy-7-(2-naphthylthio) heptanomide (HNHA), a histone deacetylase inhibitor, against breast cancer both in vitro and in vivo.

Journal: Cancer science 20110201

Title: N-hydroxy-7-(2-naphthylthio) heptanomide inhibits retinal and choroidal angiogenesis.

Journal: Molecular pharmaceutics 20090101

Title: Anti-tumor activity of N-hydroxy-7-(2-naphthylthio) heptanomide, a novel histone deacetylase inhibitor.

Journal: Biochemical and biophysical research communications 20070427

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