Home Other Building Blocks 949588-40-3
949588-40-3,MFCD19708017
Catalog No.:AA01EQC2

949588-40-3 | ORG25935-SCH900435

Pack Size
Purity
Availability
Price(USD)
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5mg
99%
in stock  
$234.00   $164.00
- +
25mg
99%
in stock  
$647.00   $453.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA01EQC2
Chemical Name:
ORG25935-SCH900435
CAS Number:
949588-40-3
Molecular Formula:
C21H26ClNO3
Molecular Weight:
375.8890
MDL Number:
MFCD19708017
SMILES:
CN(CC1CCC2=C(C1C3=CC=CC=C3)C=CC(=C2)OC)CC(=O)O.Cl
Properties
Computed Properties
 
Complexity:
435  
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
2  
Heavy Atom Count:
26  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
6  

Literature

Title: Differential effects of AMPA receptor potentiators and glycine reuptake inhibitors on antipsychotic efficacy and prefrontal glutamatergic transmission.

Journal: Psychopharmacology 20120501

Title: Evaluation of the glycine transporter inhibitor Org 25935 as augmentation to cognitive-behavioral therapy for panic disorder: a multicenter, randomized, double-blind, placebo-controlled trial.

Journal: The Journal of clinical psychiatry 20120501

Title: Glycine transporter inhibitor attenuates the psychotomimetic effects of ketamine in healthy males: preliminary evidence.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20120301

Title: Pre-synaptic glycine GlyT1 transporter--NMDA receptor interaction: relevance to NMDA autoreceptor activation in the presence of Mg2+ ions.

Journal: Journal of neurochemistry 20110501

Title: Glycine transporter-1 blockade leads to persistently reduced relapse-like alcohol drinking in rats.

Journal: Biological psychiatry 20101015

Title: The glycine reuptake inhibitor org 25935 interacts with basal and ethanol-induced dopamine release in rat nucleus accumbens.

Journal: Alcoholism, clinical and experimental research 20090701

Title: [Antinociceptive effects of glycine transporter inhibitors in neuropathic pain models in mice].

Journal: Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20071201

Title: The glycine reuptake inhibitor Org 25935 decreases ethanol intake and preference in male wistar rats.

Journal: Alcohol and alcoholism (Oxford, Oxfordshire) 20070101

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Tags:949588-40-3 Molecular Formula|949588-40-3 MDL|949588-40-3 SMILES|949588-40-3 ORG25935-SCH900435