Catalog No.:AA00IIN9

950762-95-5 | Pci-34051

Name: Name:Pci-34051
Brand: AABLOCKS
SKU: AA00IIN9
Availability: InStock
Rating: 90 (10 reviews)

Pack Size

Purity

Availability

Price(USD)

Quantity

1mg

98%

in stock

$13.00 $9.00

- +

5mg

98%

in stock

$39.00 $28.00

- +

10mg

98%

in stock

$60.00 $42.00

- +

Technical Information
Properties
Downstream Synthesis Route
Literature
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Download SDS

Technical Information
Properties
Downstream Synthesis Route
Literature

Technical Information

Catalog Number:

AA00IIN9

Chemical Name:

Pci-34051

CAS Number:

950762-95-5

Molecular Formula:

C17H16N2O3

Molecular Weight:

296.3205

MDL Number:

MFCD11114393

SMILES:

ONC(=O)c1ccc2c(c1)n(cc2)Cc1ccc(cc1)OC

Properties

Computed Properties

Complexity:

382

Covalently-Bonded Unit Count:

Heavy Atom Count:

Hydrogen Bond Acceptor Count:

Hydrogen Bond Donor Count:

Rotatable Bond Count:

XLogP3:

2.4

Downstream Synthesis Route

950763-29-8

950762-95-5

[1]CurrentPatentAssignee:ABBVIEINC-WO2007/109178,2007,A2Locationinpatent:Page/Pagecolumn94

50820-65-0

2746-25-0

950762-95-5

[1]CurrentPatentAssignee:ABBVIEINC-WO2007/109178,2007,A2

Literature

Title: A novel histone deacetylase 8 (HDAC8)-specific inhibitor PCI-34051 induces apoptosis in T-cell lymphomas.

Journal: Leukemia 20080501

Title: Balasubramanian S, et al. A novel histone deacetylase 8 (HDAC8)-specific inhibitor PCI-34051 induces apoptosis in T-cell lymphomas. Leukemia. 2008 May;22(5):1026-34.

Title: Ren Y, et al. Therapeutic effects of histone deacetylase inhibitors in a murine asthma model. Inflamm Res. 2016 Dec;65(12):995-1008.

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SDS