Name: Name:3-Phenyl-1,2-oxazole
Brand: AABLOCKS
SKU: AA0002D1
Rating: 90 (10 reviews)

Technical Information

Catalog Number: AA0002D1

Chemical Name: 3-Phenyl-1,2-oxazole

CAS Number: 1006-65-1

Molecular Formula: C9H7NO

Molecular Weight: 145.1580

MDL Number: MFCD00464218

SMILES: c1ccc(cc1)c1nocc1

Properties

Complexity: 121

Covalently-Bonded Unit Count: 1

Defined Atom Stereocenter Count: 0

Defined Bond Stereocenter Count: 0

Formal Charge: 0

Heavy Atom Count: 11

Hydrogen Bond Acceptor Count: 2

Hydrogen Bond Donor Count: 0

Isotope Atom Count: 0

Rotatable Bond Count: 1

Undefined Atom Stereocenter Count: 0

Undefined Bond Stereocenter Count: 0

XLogP3: 2

Literature fold

Title: Synthesis and biological evaluation of isoxazole, oxazole, and oxadiazole containing heteroaryl analogs of biaryl ureas as DGAT1 inhibitors.

Journal: European journal of medicinal chemistry20120801

Title: Fragment-based discovery of bromodomain inhibitors part 2: optimization of phenylisoxazole sulfonamides.

Journal: Journal of medicinal chemistry20120126

Title: Phenyl isoxazole voltage-gated sodium channel blockers: structure and activity relationship.

Journal: Bioorganic & medicinal chemistry letters20110701

Title: Novel mechanism of inhibition of human angiotensin-I-converting enzyme (ACE) by a highly specific phosphinic tripeptide.

Journal: The Biochemical journal20110515

Title: Use of the nitrile oxide cycloaddition (NOC) reaction for molecular probe generation: a new class of enzyme selective histone deacetylase inhibitors (HDACIs) showing picomolar activity at HDAC6.

Journal: Journal of medicinal chemistry20080814

Title: Carbonic anhydrase inhibitors: Valdecoxib binds to a different active site region of the human isoform II as compared to the structurally related cyclooxygenase II 'selective' inhibitor celecoxib.

Journal: Bioorganic & medicinal chemistry letters20060115

1006-65-1 | 3-Phenyl-1,2-oxazole