116644-53-2 | Acetic acid, methoxy-, (1S,2S)-2-[2-[[3-(1H-benzimidazol-2-yl)propyl]methylamino]ethyl]-6-fluoro-1,2,3,4-tetrahydro-1-(1-methylethyl)-2-naphthalenyl ester

Title: Why are most phospholipidosis inducers also hERG blockers?

Journal: Archives of toxicology 20171201

Title: Epigallocatechin-3-gallate induces mesothelioma cell death via H2 O2 -dependent T-type Ca2+ channel opening.

Journal: Journal of cellular and molecular medicine 20121101

Title: Involvement of the endogenous hydrogen sulfide/Ca(v) 3.2 T-type Ca2+ channel pathway in cystitis-related bladder pain in mice.

Journal: British journal of pharmacology 20121001

Title: Differential concentration and time dependent effects of progesterone on kinase activity, hyperactivation and acrosome reaction in human spermatozoa.

Journal: International journal of andrology 20121001

Title: Progress curve mechanistic modeling approach for assessing time-dependent inhibition of CYP3A4.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20120901

Title: T-type Ca²⁺ signalling downregulates MEK1/2 phosphorylation and cross-talk with the RAAS transcriptional response in cardiac myocytes.

Journal: Journal of molecular and cellular cardiology 20120801

Title: Hydrogen sulfide-induced mechanical hyperalgesia and allodynia require activation of both Cav3.2 and TRPA1 channels in mice.

Journal: British journal of pharmacology 20120701

Title: Time-dependent inhibition and estimation of CYP3A clinical pharmacokinetic drug-drug interactions using plated human cell systems.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20120701

Title: Mechanism-based inactivation (MBI) of cytochrome P450 enzymes: structure-activity relationships and discovery strategies to mitigate drug-drug interaction risks.

Journal: Journal of medicinal chemistry 20120614

Title: Inhibition of T-type Ca²⁺ channels by endostatin attenuates human glioblastoma cell proliferation and migration.

Journal: British journal of pharmacology 20120601

Title: Functional role of T-type calcium channels in tumour growth and progression: prospective in cancer therapy.

Journal: British journal of pharmacology 20120601

Title: The CatSper channel: a polymodal chemosensor in human sperm.

Journal: The EMBO journal 20120404

Title: The T-type voltage-gated calcium channel as a molecular target of the novel cognitive enhancer ST101: enhancement of long-term potentiation and CaMKII autophosphorylation in rat cortical slices.

Journal: Journal of neurochemistry 20120401

Title: Aortic stiffness in type-1 diabetes mellitus; beware of hypertension.

Journal: The international journal of cardiovascular imaging 20120301

Title: Does heart rate influence CMR image quality of the coronary vessel wall?

Journal: The international journal of cardiovascular imaging 20120301

Title: Evaluation of drugs with specific organ toxicities in organ-specific cell lines.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20120301

Title: Functional expression of voltage-gated calcium channels in human melanoma.

Journal: Pigment cell & melanoma research 20120301

Title: [Impact of calcium channel antagonists for estrogen action on the endometrial carcinoma HEC-1A cells].

Journal: Zhonghua fu chan ke za zhi 20120301

Title: Sigma-1 receptors do not regulate calcium influx through voltage-dependent calcium channels in mouse brain synaptosomes.

Journal: European journal of pharmacology 20120227

Title: Reduction of radiation dose using 80 kV tube voltage: a feasible strategy?

Journal: The international journal of cardiovascular imaging 20120201

Title: Br-DIF-1 accelerates dimethyl sulphoxide-induced differentiation of P19CL6 embryonic carcinoma cells into cardiomyocytes.

Journal: British journal of pharmacology 20120201

Title: 320-row CT scanning: reduction in tube current parallels reduction in radiation exposure?

Journal: The international journal of cardiovascular imaging 20120101

Title: 320-row CT: does beat-to-beat motion of the coronary arteries affect image quality?

Journal: The international journal of cardiovascular imaging 20120101

Title: Atypical Ca2+ currents in chromaffin cells from SHR and WKY rat strains result from the deficient expression of a splice variant of the α1D Ca2+ channel.

Journal: American journal of physiology. Heart and circulatory physiology 20120101

Title: Retrieval of context-associated memory is dependent on the Ca(v)3.2 T-type calcium channel.

Journal: PloS one 20120101

Title: Synthesis and pharmacological evaluation of 2-(1-alkylpiperidin-4-yl)-n-[(1r)-1-(4-fluorophenyl)-2-methylpropyl]acetamide Derivatives as Novel Antihypertensive Agents.

Journal: Chemical & pharmaceutical bulletin 20120101

Title: Network deficiency exacerbates impairment in a mouse model of retinal degeneration.

Journal: Frontiers in systems neuroscience 20120101

Title: Performance scores in general practice: a comparison between the clinical versus medication-based approach to identify target populations.

Journal: PloS one 20120101

Title: Diverse spectrum of presentation of coronary slow flow phenomenon: a concise review of the literature.

Journal: Cardiology research and practice 20120101

Title: Ischemia-induced apoptosis of intestinal epithelial cells correlates with altered integrin distribution and disassembly of F-actin triggered by calcium overload.

Journal: Journal of biomedicine & biotechnology 20120101

Title: TRPA1 has a key role in the somatic pro-nociceptive actions of hydrogen sulfide.

Journal: PloS one 20120101

Title: Neuroprotection by lomerizine, a prophylactic drug for migraine, against hydrogen peroxide-induced hippocampal neurotoxicity.

Journal: Molecular and cellular biochemistry 20111201

Title: Fatal rhabdomyolysis in a patient with liver cirrhosis after switching from simvastatin to fluvastatin.

Journal: Journal of Korean medical science 20111201

Title: Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).

Journal: PLoS computational biology 20111201

Title: Multiple T-type Ca2+ current subtypes in electrophysiologically characterized hamster dorsal horn neurons: possible role in spinal sensory integration.

Journal: Journal of neurophysiology 20111101

Title: On the origin of rhythmic calcium transients in the ICC-MP of the mouse small intestine.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20111101

Title: Closure of multiple types of K+ channels is necessary to induce changes in renal vascular resistance in vivo in rats.

Journal: Pflugers Archiv : European journal of physiology 20111101

Title: Stress imaging in patients with diabetes; routine practice?

Journal: The international journal of cardiovascular imaging 20111001

Title: Cardiac magnetic resonance imaging analysis in STEMI: quantitative or still visual?

Journal: The international journal of cardiovascular imaging 20111001

Title: Evaluation of pulmonary arterial hypertension: invasive or noninvasive?

Journal: The international journal of cardiovascular imaging 20111001

Title: IVUS detects more coronary calcifications than MSCT; matter of both resolution and cross-sectional assessment?

Journal: The international journal of cardiovascular imaging 20111001

Title: CMR-determined scar volume: predictive for ventricular tachycardias?

Journal: The international journal of cardiovascular imaging 20111001

Title: Functional analysis by 64-slice CT scanning: prediction of left ventricular dysfunction together with reduction in radiation exposure?

Journal: The international journal of cardiovascular imaging 20111001

Title: Coding movement direction by burst firing in electrosensory neurons.

Journal: Journal of neurophysiology 20111001

Title: Sodium influx induced by external calcium chelation decreases human sperm motility.

Journal: Human reproduction (Oxford, England) 20111001

Title: Synthesis and biological evaluation of 4-piperidinecarboxylate and 4-piperidinecyanide derivatives for T-type calcium channel blockers.

Journal: Bioorganic & medicinal chemistry letters 20111001

Title: Synthesis and pharmacological evaluation of 1-alkyl-N-[2-ethyl-2-(4-fluorophenyl)butyl]piperidine-4-carboxamide derivatives as novel antihypertensive agents.

Journal: Bioorganic & medicinal chemistry 20110915

Title: The sound of silence: ionic mechanisms encoding sound termination.

Journal: Neuron 20110908

Title: Functional importance of L- and P/Q-type voltage-gated calcium channels in human renal vasculature.

Journal: Hypertension (Dallas, Tex. : 1979) 20110901

Title: Sound rhythms are encoded by postinhibitory rebound spiking in the superior paraolivary nucleus.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20110831

Title: NaChBac: the long lost sodium channel ancestor.

Journal: Biochemistry 20110816

Title: Activation of voltage-gated Na⁺ and Ca²⁺ channels is required for glutamate release from retinal glial cells implicated in cell volume regulation.

Journal: Neuroscience 20110811

Title: Inhibition of T-type calcium channels and hydrogen sulfide-forming enzyme reverses paclitaxel-evoked neuropathic hyperalgesia in rats.

Journal: Neuroscience 20110811

Title: Two structurally different T-type Ca 2+ channel inhibitors, mibefradil and pimozide, protect CA1 neurons from delayed death after global ischemia in rats.

Journal: Fundamental & clinical pharmacology 20110801

Title: TRPC1, STIM1, and ORAI influence signal-regulated intracellular and endoplasmic reticulum calcium dynamics in human myometrial cells.

Journal: Biology of reproduction 20110801

Title: Modulation of subthalamic T-type Ca(2+) channels remedies locomotor deficits in a rat model of Parkinson disease.

Journal: The Journal of clinical investigation 20110801

Title: Simulation of multiple ion channel block provides improved early prediction of compounds' clinical torsadogenic risk.

Journal: Cardiovascular research 20110701

Title: Mechanism-based inactivation of cytochrome P450 3A4 by mibefradil through heme destruction.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20110701

Title: Quantitative prediction of mechanism-based inhibition caused by mibefradil in rats.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20110701

Title: Regulation of spinal substance p release by intrathecal calcium channel blockade.

Journal: Anesthesiology 20110701

Title: Synaptically driven state transitions in distal dendrites of striatal spiny neurons.

Journal: Nature neuroscience 20110701

Title: Scorpion toxins modify phytopathogenic fungus physiology. A possible source of new fungicides.

Journal: Journal of agricultural and food chemistry 20110608

Title: Blockade of T-type Ca(2+) channels inhibits human ovarian cancer cell proliferation.

Journal: Cancer investigation 20110601

Title: The influence of high-dose simvastatin and diltiazem on myocardium in rabbits: a haemodynamic study.

Journal: Archives of medical science : AMS 20110601

Title: Simplified bacterial 'pore' channel provides insight into the assembly, stability, and structure of sodium channels.

Journal: The Journal of biological chemistry 20110506

Title: Chelating luminal zinc mimics hydrogen sulfide-evoked colonic pain in mice: possible involvement of T-type calcium channels.

Journal: Neuroscience 20110505

Title: 100 kV versus 120 kV: effective reduction in radiation dose?

Journal: The international journal of cardiovascular imaging 20110401

Title: Assessment of left ventricular volumes; reliable by gated SPECT?

Journal: The international journal of cardiovascular imaging 20110401

Title: Assessment of left ventricular function: visual or quantitative?

Journal: The international journal of cardiovascular imaging 20110401

Title: T-type Ca²+ signalling regulates aldosterone-induced CREB activation and cell death through PP2A activation in neonatal cardiomyocytes.

Journal: Cardiovascular research 20110401

Title: The CatSper channel mediates progesterone-induced Ca2+ influx in human sperm.

Journal: Nature 20110317

Title: T-type voltage-gated calcium channels regulate the tone of mouse efferent arterioles.

Journal: Kidney international 20110201

Title: Effects of T-type calcium channel blockers on a parkinsonian tremor model in rats.

Journal: Pharmacology, biochemistry, and behavior 20110201

Title: Cardiac magnetic resonance imaging; gatekeeper in suspected CAD?

Journal: The international journal of cardiovascular imaging 20110101

Title: Evidence of scar tissue: contra-indication to cardiac resynchronization therapy?

Journal: The international journal of cardiovascular imaging 20110101

Title: Speckle tracking: distinction of physiologic from pathologic LVH?

Journal: The international journal of cardiovascular imaging 20110101

Title: Facile synthesis and biological evaluation of 3,3-diphenylpropanoyl piperazines as T-type calcium channel blockers.

Journal: Bioorganic & medicinal chemistry letters 20110101

Title: Gray matter NG2 cells display multiple Ca2+-signaling pathways and highly motile processes.

Journal: PloS one 20110101

Title: A computational model of the ionic currents, Ca2+ dynamics and action potentials underlying contraction of isolated uterine smooth muscle.

Journal: PloS one 20110101

Title: Involvement of the Cav3.2 T-type calcium channel in thalamic neuron discharge patterns.

Journal: Molecular pain 20110101

Title: Coronary artery ligation and intramyocardial injection in a murine model of infarction.

Journal: Journal of visualized experiments : JoVE 20110101

Title: Potassium-induced intermittent vasomotion in rat isolated pulmonary artery.

Journal: Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi 20110101

Title: Biophysically based modeling of the interstitial cells of cajal: current status and future perspectives.

Journal: Frontiers in physiology 20110101

Title: δ-Sarcoglycan-deficient muscular dystrophy: from discovery to therapeutic approaches.

Journal: Skeletal muscle 20110101

Title: Identification of novel functional inhibitors of acid sphingomyelinase.

Journal: PloS one 20110101

Title: Serotonin augments gut pacemaker activity via 5-HT3 receptors.

Journal: PloS one 20110101

Title: Synthesis and pharmacological evaluation of 1-alkyl-N-[(1R)-1-(4-fluorophenyl)-2-methylpropyl]piperidine-4-carboxamide derivatives as novel antihypertensive agents.

Journal: Chemical & pharmaceutical bulletin 20110101

Title: Distribution of extracellular glutamate in the neuropil of hippocampus.

Journal: PloS one 20110101

Title: Use of the anterior-posterior chest diameter in CT: reduction in radiation dose?

Journal: The international journal of cardiovascular imaging 20101201

Title: Gated myocardial SPECT imaging; true additional value in AMI?

Journal: The international journal of cardiovascular imaging 20101201

Title: Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20101201

Title: A predictive ligand-based Bayesian model for human drug-induced liver injury.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20101201

Title: Identification of human Ether-à-go-go related gene modulators by three screening platforms in an academic drug-discovery setting.

Journal: Assay and drug development technologies 20101201

Title: Design, syntheses, and SAR of 2,8-diazaspiro[4.5]decanones as T-type calcium channel antagonists.

Journal: Bioorganic & medicinal chemistry letters 20101115

Title: T-type calcium channel antagonists suppress tremor in two mouse models of essential tremor.

Journal: Neuropharmacology 20101101

Title: Inhibitory actions of mibefradil on steroidogenesis in mouse Leydig cells: involvement of Ca(2+) entry via the T-type Ca(2+) channel.

Journal: Asian journal of andrology 20101101

Title: Phosphorylation of ERK in the spinal dorsal horn following pancreatic pronociceptive stimuli with proteinase-activated receptor-2 agonists and hydrogen sulfide in rats: evidence for involvement of distinct mechanisms.

Journal: Journal of neuroscience research 20101101

Title: Voltage-gated divalent currents in descending vasa recta pericytes.

Journal: American journal of physiology. Renal physiology 20101001

Title: Effects of T-type calcium channel blockers on cocaine-induced hyperlocomotion and thalamocortical GABAergic abnormalities in mice.

Journal: Psychopharmacology 20101001

Title: Biophysical properties of human medulloblastoma cells.

Journal: The Journal of membrane biology 20101001

Title: Rebound discharge in deep cerebellar nuclear neurons in vitro.

Journal: Cerebellum (London, England) 20100901

Title: Altered protein kinase C regulation of pulmonary endothelial store- and receptor-operated Ca2+ entry after chronic hypoxia.

Journal: The Journal of pharmacology and experimental therapeutics 20100901

Title: Evidence both L-type and non-L-type voltage-dependent calcium channels contribute to cerebral artery vasospasm following loss of NO in the rat.

Journal: Vascular pharmacology 20100901

Title: Endothelin-1 (ET-1) increases the expression of remodeling genes in vascular smooth muscle through linked calcium and cAMP pathways: role of a phospholipase A(2)(cPLA(2))/cyclooxygenase-2 (COX-2)/prostacyclin receptor-dependent autocrine loop.

Journal: The Journal of biological chemistry 20100820

Title: Synthesis and T-type calcium channel blocking activity of novel diphenylpiperazine compounds, and evaluation of in vivo analgesic activity.

Journal: Bioorganic & medicinal chemistry 20100815

Title: NADPH oxidase-dependent regulation of T-type Ca2+ channels and ryanodine receptors mediate the augmented exocytosis of catecholamines from intermittent hypoxia-treated neonatal rat chromaffin cells.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20100811

Title: Comparative effects of T-type and L-type Ca(2+)-antagonists against noradrenaline-induced contractions of human vas deferens.

Journal: BJU international 20100801

Title: Positron emission tomography; viable tool in patients pre-CABG?

Journal: The international journal of cardiovascular imaging 20100801

Title: Decoding glutamate receptor activation by the Ca2+ sensor protein hippocalcin in rat hippocampal neurons.

Journal: The European journal of neuroscience 20100801

Title: Synthesis and biological evaluation of oxazole derivatives as T-type calcium channel blockers.

Journal: Bioorganic & medicinal chemistry letters 20100715

Title: Alpha1G T-type calcium channel selectively regulates P-selectin surface expression in pulmonary capillary endothelium.

Journal: American journal of physiology. Lung cellular and molecular physiology 20100701

Title: Changes in aortic stiffness related to elastic fiber network anomalies in the Brown Norway rat during maturation and aging.

Journal: American journal of physiology. Heart and circulatory physiology 20100701

Title: Involvement of Src kinase in T-type calcium channel-dependent neuronal differentiation of NG108-15 cells by hydrogen sulfide.

Journal: Journal of neurochemistry 20100701

Title: Upregulation of Ca(v)3.2 T-type calcium channels targeted by endogenous hydrogen sulfide contributes to maintenance of neuropathic pain.

Journal: Pain 20100701

Title: Dihydropyridine-insensitive calcium currents contribute to function of small cerebral arteries.

Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20100601

Title: Echocardiography in Takotsubo cardiomyopathy; a useful approach?

Journal: The international journal of cardiovascular imaging 20100601

Title: Increased accuracy in computed tomography coronary angiography; a new body surface area adapted protocol.

Journal: The international journal of cardiovascular imaging 20100601

Title: Involvement of CaV3.1 T-type calcium channels in cell proliferation in mouse preadipocytes.

Journal: American journal of physiology. Cell physiology 20100601

Title: Synaptic integration of rhythmogenic neurons in the locomotor circuitry: the case of Hb9 interneurons.

Journal: Annals of the New York Academy of Sciences 20100601

Title: Fast- or slow-inactivated state preference of Na+ channel inhibitors: a simulation and experimental study.

Journal: PLoS computational biology 20100601

Title: Recombinant human ZP3-induced sperm acrosome reaction: evidence for the involvement of T- and L-type voltage-gated calcium channels.

Journal: Biochemical and biophysical research communications 20100514

Title: T-type Ca(2+) channel modulation by otilonium bromide.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20100501

Title: Synthesis and biological evaluation of 1,4-diazepane derivatives as T-type calcium channel blockers.

Journal: Bioorganic & medicinal chemistry letters 20100501

Title: The vasoactive peptides urotensin II and urotensin II-related peptide regulate astrocyte activity through common and distinct mechanisms: involvement in cell proliferation.

Journal: The Biochemical journal 20100428

Title: Electrophysiological effects of neuropeptide S on rat ventromedial hypothalamic neurons in vitro.

Journal: Peptides 20100401

Title: Electrical stimulation induces calcium-dependent release of NGF from cultured Schwann cells.

Journal: Glia 20100401

Title: Angiotensin II regulates endothelial cell migration through calcium influx via T-type calcium channel in human umbilical vein endothelial cells.

Journal: Acta physiologica (Oxford, England) 20100401

Title: Left ventricular mass assessment by CMR; how to define the optimal index.

Journal: The international journal of cardiovascular imaging 20100401

Title: Regulation of phagocyte NADPH oxidase by hydrogen peroxide through a Ca(2+)/c-Abl signaling pathway.

Journal: Free radical biology & medicine 20100315

Title: Transient and big are key features of an invertebrate T-type channel (LCav3) from the central nervous system of Lymnaea stagnalis.

Journal: The Journal of biological chemistry 20100305

Title: CT perfusion angiography; beware of artifacts!

Journal: The international journal of cardiovascular imaging 20100301

Title: Effects of T-type calcium channel blockers and thalidomide on contractions of rat vas deferens.

Journal: British journal of pharmacology 20100301

Title: Cardiac resynchronization therapy; the importance of evaluating cardiac metabolism.

Journal: The international journal of cardiovascular imaging 20100301

Title: Cardiovascular dynamics in ischemic cardiomyopathy during exercise.

Journal: The international journal of cardiovascular imaging 20100201

Title: Fingertip digital thermal monitoring: a fingerprint for cardiovascular disease?

Journal: The international journal of cardiovascular imaging 20100201

Title: Cardiac resynchronization therapy; evaluation by advanced imaging techniques.

Journal: The international journal of cardiovascular imaging 20100201

Title: Distal protection beneficial?

Journal: The international journal of cardiovascular imaging 20100201

Title: Mitral valve prolapse: a source of arrhythmias?

Journal: The international journal of cardiovascular imaging 20100201

Title: Tissue characterization in Takotsubo cardiomyopathy; a valuable approach?

Journal: The international journal of cardiovascular imaging 20100201

Title: Mechanisms involved in the regulation of bovine pulmonary vascular tone by the 5-HT1B receptor.

Journal: British journal of pharmacology 20100101

Title: Delineation of downstream signalling components during acrosome reaction mediated by heat solubilized human zona pellucida.

Journal: Reproductive biology and endocrinology : RB&E 20100101

Title: Regulation of adrenal aldosterone production by serine protease prostasin.

Journal: Journal of biomedicine & biotechnology 20100101

Title: GABA(A) Increases Calcium in Subventricular Zone Astrocyte-Like Cells Through L- and T-Type Voltage-Gated Calcium Channels.

Journal: Frontiers in cellular neuroscience 20100101

Title: The roles of T-type calcium channel in the development of neuropathic pain following chronic compression of rat dorsal root ganglia.

Journal: Pharmacology 20100101

Title: Axons amplify somatic incomplete spikes into uniform amplitudes in mouse cortical pyramidal neurons.

Journal: PloS one 20100101

Title: Fast, repetitive light-activation of CaV3.2 using channelrhodopsin 2.

Journal: Channels (Austin, Tex.) 20100101

Title: Rift valley fever virus infection of human cells and insect hosts is promoted by protein kinase C epsilon.

Journal: PloS one 20100101

Title: Stereoselective Inhibition of the hERG1 Potassium Channel.

Journal: Frontiers in pharmacology 20100101

Title: Transduction mechanism(s) of Na-saccharin in the blowfly Protophormia terraenovae: evidence for potassium and calcium conductance involvement.

Journal: Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology 20091201

Title: Selective T-type calcium channel blockade alleviates hyperalgesia in ob/ob mice.

Journal: Diabetes 20091101

Title: Voltage-dependent Ca2+ currents contribute to spontaneous Ca2+ waves in rabbit corpus cavernosum myocytes.

Journal: The journal of sexual medicine 20091101

Title: A role of functional T-type Ca2+ channel in hepatocellular carcinoma cell proliferation.

Journal: Oncology reports 20091101

Title: Acid-evoked Ca2+ signalling in rat sensory neurones: effects of anoxia and aglycaemia.

Journal: Pflugers Archiv : European journal of physiology 20091101

Title: Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.

Journal: Bioorganic & medicinal chemistry 20091001

Title: T-type Ca2+ channel blockade prevents sudden death in mice with heart failure.

Journal: Circulation 20090901

Title: Evaluating patients with persistent chest pain and no obstructive coronary artery disease.

Journal: JAMA 20090812

Title: Low-dose CT angiography: sufficient contrast for vessel imaging?

Journal: The international journal of cardiovascular imaging 20090801

Title: Cardiac magnetic resonance imaging in primary PCI: additional value?

Journal: The international journal of cardiovascular imaging 20090801

Title: [Calcium channel mechanism by which betaine promotes proliferation of lymphocytes in mice].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20090801

Title: Is combined L- and T-channel blockade better than L-channel blockade in therapy?

Journal: Hypertension (Dallas, Tex. : 1979) 20090701

Title: A genome-wide association study of hypertension and blood pressure in African Americans.

Journal: PLoS genetics 20090701

Title: Luminal hydrogen sulfide plays a pronociceptive role in mouse colon.

Journal: Gut 20090601

Title: Hydrogen sulfide as a novel mediator for pancreatic pain in rodents.

Journal: Gut 20090601

Title: Mechanisms of U46619-induced contraction of rat pulmonary arteries in the presence and absence of the endothelium.

Journal: British journal of pharmacology 20090601

Title: Role of T-type Ca Channels in the Spontaneous Phasic Contraction of Pregnant Rat Uterine Smooth Muscle.

Journal: The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 20090601

Title: Amiloride inhibits hydrogen peroxide-induced Ca2+ responses in human CNS pericytes.

Journal: Microvascular research 20090501

Title: Valsartan vs. other angiotensin II receptor blockers in the treatment of hypertension: a meta-analytical approach.

Journal: International journal of clinical practice 20090501

Title: Heterogeneity of L- and T-channels in the vasculature: rationale for the efficacy of combined L- and T-blockade.

Journal: Hypertension (Dallas, Tex. : 1979) 20090401

Title: Microbiological appraisal of levofloxacin activity against Pseudomonas aeruginosa biofilm in combination with different calcium chanel blockers in vitro.

Journal: Journal of chemotherapy (Florence, Italy) 20090401

Title: Hyperalgesia induced by spinal and peripheral hydrogen sulfide: evidence for involvement of Cav3.2 T-type calcium channels.

Journal: Pain 20090301

Title: High throughput screening assay of alpha(1G) T-type Ca2+ channels and comparison with patch-clamp studies.

Journal: Combinatorial chemistry & high throughput screening 20090301

Title: Stimulation of alpha(1)-adrenoceptors reduces glutamatergic synaptic input from primary afferents through GABA(A) receptors and T-type Ca(2+) channels.

Journal: Neuroscience 20090218

Title: Egg water from the amphibian Bufo arenarum modulates the ability of homologous sperm to undergo the acrosome reaction in the presence of the vitelline envelope.

Journal: Biology of reproduction 20090201

Title: Molecular pharmacology of human Cav3.2 T-type Ca2+ channels: block by antihypertensives, antiarrhythmics, and their analogs.

Journal: The Journal of pharmacology and experimental therapeutics 20090201

Title: Hydrogen sulfide evokes neurite outgrowth and expression of high-voltage-activated Ca2+ currents in NG108-15 cells: involvement of T-type Ca2+ channels.

Journal: Journal of neurochemistry 20090201

Title: T-type calcium channels mediate rebound firing in intact deep cerebellar neurons.

Journal: Neuroscience 20090123

Title: T- and L-type calcium channels mediate alpha(1)-adrenoceptor-evoked contraction in the guinea-pig vas deferens.

Journal: Neurourology and urodynamics 20090101

Title: The alpha1H Ca2+ channel subunit is expressed in mouse jejunal interstitial cells of Cajal and myocytes.

Journal: Journal of cellular and molecular medicine 20090101

Title: 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) induces calcium influx through T-type calcium channel and enhances lysosomal exocytosis and insulin secretion in INS-1 cells.

Journal: International journal of toxicology 20090101

Title: Positive allosteric interaction of structurally diverse T-type calcium channel antagonists.

Journal: Cell biochemistry and biophysics 20090101

Title: The endogenous hydrogen sulfide producing enzyme cystathionine-beta synthase contributes to visceral hypersensitivity in a rat model of irritable bowel syndrome.

Journal: Molecular pain 20090101

Title: Inhibition of human mesangial cell proliferation by targeting T-type calcium channels.

Journal: Nephron. Experimental nephrology 20090101

Title: Cholinergic receptor pathways involved in apoptosis, cell proliferation and neuronal differentiation.

Journal: Cell communication and signaling : CCS 20090101

Title: Neuroprotective effects of blockers for T-type calcium channels.

Journal: Molecular neurodegeneration 20090101

Title: Identification and characterization of a dual-acting antinematodal agent against the pinewood nematode, Bursaphelenchus xylophilus.

Journal: PloS one 20090101

Title: A pharmacovigilance study of antihypertensive medicines at a South delhi hospital.

Journal: Indian journal of pharmaceutical sciences 20090101

Title: Excitatory effects of low-level lead exposure on action potential firing of pyramidal neurons in CA1 region of rat hippocampal slices.

Journal: Journal of neuroscience research 20081201

Title: Prediction of CYP-mediated drug interactions in vivo using in vitro data.

Journal: IDrugs : the investigational drugs journal 20081201

Title: Mechanisms of unmodified CdSe quantum dot-induced elevation of cytoplasmic calcium levels in primary cultures of rat hippocampal neurons.

Journal: Biomaterials 20081101

Title: Effects of distension on airway inflammation and venular P-selectin expression.

Journal: American journal of physiology. Lung cellular and molecular physiology 20081101

Title: Discovery of 1,4-substituted piperidines as potent and selective inhibitors of T-type calcium channels.

Journal: Journal of medicinal chemistry 20081023

Title: Proliferation of human lens epithelial cells (HLE-B3) is inhibited by blocking of voltage-gated calcium channels.

Journal: Pflugers Archiv : European journal of physiology 20081001

Title: Treatment of essential hypertension does not normalize capillary rarefaction.

Journal: Clinics (Sao Paulo, Brazil) 20081001

Title: Staurosporine rapidly commits 3T3-F442A cells to the formation of adipocytes by activation of GSK-3beta and mobilization of calcium.

Journal: Journal of cellular biochemistry 20080901

Title: The dihydropyridine isradipine inhibits the murine but not the bovine A-wave response of the electroretinogram.

Journal: Acta ophthalmologica 20080901

Title: Requirements of calcium fluxes and ERK kinase activation for glucose- and interleukin-1beta-induced beta-cell apoptosis.

Journal: Molecular and cellular biochemistry 20080801

Title: Synthesis and evaluation of alpha,alpha'-disubstituted phenylacetate derivatives for T-type calcium channel blockers.

Journal: Bioorganic & medicinal chemistry letters 20080801

Title: Involvement of T-type Ca2+ channels in the potentiation of synaptic and visual responses during the critical period in rat visual cortex.

Journal: The European journal of neuroscience 20080801

Title: The mibefradil derivative NNC55-0396, a specific T-type calcium channel antagonist, exhibits less CYP3A4 inhibition than mibefradil.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20080701

Title: Facilitation of Ca2+-activated K+ channels (IKCa1) by mibefradil in B lymphocytes.

Journal: Pflugers Archiv : European journal of physiology 20080601

Title: A selective T-type Ca2+ channel blocker R(-) efonidipine.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20080601

Title: The T- and L-type calcium channel blocker (CCB) mibefradil attenuates leg edema induced by the L-type CCB nifedipine in the spontaneously hypertensive rat: a novel differentiating assay.

Journal: The Journal of pharmacology and experimental therapeutics 20080601

Title: Coincidence detection of convergent perforant path and mossy fibre inputs by CA3 interneurons.

Journal: The Journal of physiology 20080601

Title: T-type Ca2+ channels, SK2 channels and SERCAs gate sleep-related oscillations in thalamic dendrites.

Journal: Nature neuroscience 20080601

Title: Enzyme systems of detoxication - overview of recent approaches.

Journal: Interdisciplinary toxicology 20080601

Title: Blockade of T-type voltage-dependent Ca2+ channels by benidipine, a dihydropyridine calcium channel blocker, inhibits aldosterone production in human adrenocortical cell line NCI-H295R.

Journal: European journal of pharmacology 20080428

Title: Molecular and biophysical properties of voltage-gated Na+ channels in murine vas deferens.

Journal: Biophysical journal 20080415

Title: Contributions of voltage- and Ca2+-activated conductances to GABA-induced depolarization in spider mechanosensory neurons.

Journal: Journal of neurophysiology 20080401

Title: In vivo approach for the evaluation of mechanism-based inhibition of cytochrome P450 3A in rats.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20080401

Title: The CaV3.1 T-type Ca2+channel contributes to voltage-dependent calcium currents in rat outer hair cells.

Journal: Brain research 20080327

Title: Follicle-stimulating hormone-induced Galphah/phospholipase C-delta1 signaling mediating a noncapacitative Ca2+ influx through T-type Ca2+ channels in rat sertoli cells.

Journal: Endocrinology 20080301

Title: Participation of low-threshold Ca2+ spike in the Purkinje cells complex spike.

Journal: Neuroreport 20080212

Title: Mechanisms of potassium- and capsaicin-induced axonal calcitonin gene-related peptide release: involvement of L- and T-type calcium channels and TRPV1 but not sodium channels.

Journal: Neuroscience 20080206

Title: Partial restoration of mutant enzyme homeostasis in three distinct lysosomal storage disease cell lines by altering calcium homeostasis.

Journal: PLoS biology 20080201

Title: Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.

Journal: Journal of medicinal chemistry 20080124

Title: T-type Ca2+ channel expression in human esophageal carcinomas: a functional role in proliferation.

Journal: Cell calcium 20080101

Title: K+ channel regulator KCR1 suppresses heart rhythm by modulating the pacemaker current If.

Journal: PloS one 20080101

Title: Potential strategies for minimizing mechanism-based inhibition of cytochrome P450 3A4.

Journal: Current pharmaceutical design 20080101

Title: Long-term potentiation at C-fibre synapses by low-level presynaptic activity in vivo.

Journal: Molecular pain 20080101

Title: Prevention of lens epithelial cell growth in vitro using mibefradil-containing PLGA micro particles.

Journal: The open ophthalmology journal 20080101

Title: Hydrogen sulfide as a novel nociceptive messenger.

Journal: Pain 20071101

Title: Voltage-gated Ca2+ currents are necessary for slow-wave propagation in the canine gastric antrum.

Journal: American journal of physiology. Cell physiology 20071101

Title: Discovery of potent T-type calcium channel blocker.

Journal: Bioorganic & medicinal chemistry letters 20071101

Title: Older versus newer antidepressants: substance P or calcium antagonism?

Journal: Canadian journal of physiology and pharmacology 20071001

Title: T-current related effects of antiepileptic drugs and a Ca2+ channel antagonist on thalamic relay and local circuit interneurons in a rat model of absence epilepsy.

Journal: Neuropharmacology 20070901

Title: Excitability constraints on voltage-gated sodium channels.

Journal: PLoS computational biology 20070901

Title: Glutamate-induced calcium transients in rat neurons of the dorsal motor nucleus of the vagus.

Journal: Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 20070801

Title: Mechanisms of U46619- and 5-HT-induced contraction of bovine pulmonary arteries: role of chloride ions.

Journal: British journal of pharmacology 20070801

Title: Risk assessment for drug-drug interaction caused by metabolism-based inhibition of CYP3A using automated in vitro assay systems and its application in the early drug discovery process.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20070701

Title: Mutation of delta-sarcoglycan is associated with Ca(2+) -dependent vascular remodeling in the Syrian hamster.

Journal: The American journal of pathology 20070701

Title: Fluorescently labeled analogues of dofetilide as high-affinity fluorescence polarization ligands for the human ether-a-go-go-related gene (hERG) channel.

Journal: Journal of medicinal chemistry 20070628

Title: Acidic extracellular pH increases calcium influx-triggered phospholipase D activity along with acidic sphingomyelinase activation to induce matrix metalloproteinase-9 expression in mouse metastatic melanoma.

Journal: The FEBS journal 20070601

Title: Voltage-dependent calcium channels of dog basilar artery.

Journal: The Journal of physiology 20070415

Title: Cav3.1 (alpha1G) controls von Willebrand factor secretion in rat pulmonary microvascular endothelial cells.

Journal: American journal of physiology. Lung cellular and molecular physiology 20070401

Title: Validation of high throughput screening assays against three subtypes of Ca(v)3 T-type channels using molecular and pharmacologic approaches.

Journal: Assay and drug development technologies 20070401

Title: Effects of genistein, resveratrol, and quercetin on steroidogenesis and proliferation of MA-10 mouse Leydig tumor cells.

Journal: The Journal of endocrinology 20070301

Title: Ca2+ channel subtypes and pharmacology in the kidney.

Journal: Circulation research 20070216

Title: Mibefradil-sensitive component involved in the plateau potential in submucosal interstitial cells of the murine proximal colon.

Journal: Biochemical and biophysical research communications 20070202

Title: Lead discovery and optimization of T-type calcium channel blockers.

Journal: Bioorganic & medicinal chemistry 20070201

Title: Effects of intrathecal injection of T-type calcium channel blockers in the rat formalin test.

Journal: Behavioural pharmacology 20070201

Title: T-type Ca2+ channels mediate propagation of odor-induced Ca2+ transients in rat olfactory receptor neurons.

Journal: Neuroscience 20070119

Title: Synthesis and biological evaluation of novel T-type calcium channel blockers.

Journal: Bioorganic & medicinal chemistry letters 20070115

Title: 3D pharmacophore based virtual screening of T-type calcium channel blockers.

Journal: Bioorganic & medicinal chemistry 20070115

Title: Unitary IPSPs enhance hilar mossy cell gain in the rat hippocampus.

Journal: The Journal of physiology 20070115

Title: Design, synthesis, and biological evaluation of 1,3-dioxoisoindoline-5-carboxamide derivatives as T-type calcium channel blockers.

Journal: Bioorganic & medicinal chemistry letters 20070115

Title: Resonance (approximately 10 Hz) of excitatory networks in motor cortex: effects of voltage-dependent ion channel blockers.

Journal: The Journal of physiology 20070101

Title: Novel T-type calcium channel blockers: dioxoquinazoline carboxamide derivatives.

Journal: Bioorganic & medicinal chemistry 20070101

Title: T-type Ca2+ channels contribute to IBMX/forskolin- and K(+)-induced Ca(2+) transients in porcine olfactory receptor neurons.

Journal: Neuroscience research 20070101

Title: Long-term calcium antagonist treatment of human hypertension with mibefradil or amlodipine increases sympathetic nerve activity.

Journal: Journal of hypertension 20070101

Title: L, P-/Q- and T-type Ca2+ channels in smooth muscle cells from human umbilical artery.

Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20070101

Title: Fractal michaelis-menten kinetics under steady state conditions: Application to mibefradil.

Journal: Pharmaceutical research 20061201

Title: An inner pore residue (Asn406) in the Nav1.5 channel controls slow inactivation and enhances mibefradil block to T-type Ca2+ channel levels.

Journal: Molecular pharmacology 20061101

Title: Morpholin-2-one derivatives as novel selective T-type Ca2+ channel blockers.

Journal: Bioorganic & medicinal chemistry letters 20061001

Title: Role of store-operated calcium channels and calcium sensitization in normoxic contraction of the ductus arteriosus.

Journal: Circulation 20060926

Title: Pharmacological characterization of recombinant N-type calcium channel (Cav2.2) mediated calcium mobilization using FLIPR.

Journal: Biochemical pharmacology 20060914

Title: Haloperidol induces calcium ion influx via L-type calcium channels in hippocampal HN33 cells and renders the neurons more susceptible to oxidative stress.

Journal: Molecules and cells 20060831

Title: Atorvastatin inhibits angiotensin II-induced T-type Ca2+ channel expression in endothelial cells.

Journal: Biochemical and biophysical research communications 20060825

Title: Mibefradil, a T-type Ca2+ channel blocker, protects against mesenteric ischemia-reperfusion-induced oxidative injury and histologic alterations in intestinal mucosa in rats.

Journal: Digestive diseases and sciences 20060801

Title: Angiotensin II inhibition reduces stress sensitivity of hypothalamo-pituitary-adrenal axis in spontaneously hypertensive rats.

Journal: Endocrinology 20060701

Title: Inhibitory effects of various L-type and T-type calcium antagonists on electrically generated, potassium-induced and carbachol-induced contractions of porcine detrusor muscle.

Journal: Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 20060601

Title: Presynaptic GABA(B) receptors regulate retinohypothalamic tract synaptic transmission by inhibiting voltage-gated Ca2+ channels.

Journal: Journal of neurophysiology 20060601

Title: Sodium-, chloride-, and mibefradil-sensitive calcium channels in intestinal pacing in wild-type and W/WV mice.

Journal: Canadian journal of physiology and pharmacology 20060601

Title: Synthesis and SAR studies of a novel series of T-type calcium channel blockers.

Journal: Bioorganic & medicinal chemistry 20060515

Title: Spatial and temporal mapping of pacemaker activity in interstitial cells of Cajal in mouse ileum in situ.

Journal: American journal of physiology. Cell physiology 20060501

Title: Mechanisms underlying afterload-induced exacerbation of myocardial infarct size: role of T-type Ca2+ channel.

Journal: Hypertension (Dallas, Tex. : 1979) 20060501

Title: Inhibitory effects of L- and T-type calcium antagonists on contractions of human detrusor muscle.

Journal: European journal of clinical pharmacology 20060501

Title: Prediction of hepatic clearance using cryopreserved human hepatocytes: a comparison of serum and serum-free incubations.

Journal: The Journal of pharmacy and pharmacology 20060501

Title: T-type CaV3.3 calcium channels produce spontaneous low-threshold action potentials and intracellular calcium oscillations.

Journal: The European journal of neuroscience 20060501

Title: Drug therapy for obstructive sleep apnoea in adults.

Journal: The Cochrane database of systematic reviews 20060419

Title: A role for voltage gated T-type calcium channels in mediating 'capacitative' calcium entry?

Journal: Cell calcium 20060401

Title: Zinc and mercuric ions distinguish TRESK from the other two-pore-domain K+ channels.

Journal: Molecular pharmacology 20060301

Title: Acquired cadmium resistance in metallothionein-I/II(-/-) knockout cells: role of the T-type calcium channel Cacnalpha1G in cadmium uptake.

Journal: Molecular pharmacology 20060201

Title: Antihypertensive effects of the putative T-type calcium channel antagonist mibefradil are mediated by the L-type calcium channel Cav1.2.

Journal: Circulation research 20060106

Title: Relaxant responses to calcium channel antagonists and potassium channel opener in human saphenous vein.

Journal: Autonomic & autacoid pharmacology 20060101

Title: Inhibitory effect of efonidipine on aldosterone synthesis and secretion in human adrenocarcinoma (H295R) cells.

Journal: Journal of cardiovascular pharmacology 20060101

Title: Early activation of internal medial smooth muscle cells in the rabbit aorta after mechanical injury: relationship with intimal thickening and pharmacological applications.

Journal: Clinical and experimental pharmacology & physiology 20060101

Title: Actions of mibefradil, efonidipine and nifedipine block of recombinant T- and L-type Ca channels with distinct inhibitory mechanisms.

Journal: Pharmacology 20060101

Title: Ion channel clustering enhances weak electric field detection by neutrophils: apparent roles of SKF96365-sensitive cation channels and myeloperoxidase trafficking in cellular responses.

Journal: European biophysics journal : EBJ 20051201

Title: Divergent action of calcium channel blockers on ATP-binding cassette protein expression.

Journal: Journal of cardiovascular pharmacology 20051201

Title: Role of high-voltage-activated calcium channels in glucose-regulated beta-cell calcium homeostasis and insulin release.

Journal: American journal of physiology. Endocrinology and metabolism 20051101

Title: Pathophysiological significance of T-type Ca2+ channels: T-type Ca2+ channels and drug development.

Journal: Journal of pharmacological sciences 20051101

Title: The antihyperalgesic effects of the T-type calcium channel blockers ethosuximide, trimethadione, and mibefradil.

Journal: European journal of pharmacology 20051003

Title: Cytochrome p450 enzymes mechanism based inhibitors: common sub-structures and reactivity.

Journal: Current drug metabolism 20051001

Title: A Ni(2+)-sensitive component of the ERG b-wave from the isolated bovine retina is related to E-type voltage-gated Ca(2+) channels.

Journal: Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20050901

Title: Descending vasa recta pericytes express voltage operated Na+ conductance in the rat.

Journal: The Journal of physiology 20050901

Title: Effects of calcium channel blocker, mibefradil, and potassium channel opener, pinacidil, on the contractile response of mid-pregnant goat myometrium.

Journal: Indian journal of experimental biology 20050901

Title: T-type calcium channel trigger p21ras signaling pathway to ERK in Cav3.1-expressed HEK293 cells.

Journal: Brain research 20050823

Title: Characterization of a proton-activated, outwardly rectifying anion channel.

Journal: The Journal of physiology 20050815

Title: Effect of mibefradil on sodium and calcium currents.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20050801

Title: Automated screening with confirmation of mechanism-based inactivation of CYP3A4, CYP2C9, CYP2C19, CYP2D6, and CYP1A2 in pooled human liver microsomes.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20050801

Title: Aldosterone increases T-type calcium channel expression and in vitro beating frequency in neonatal rat cardiomyocytes.

Journal: Cardiovascular research 20050801

Title: Involvement of different calcium channels in the depolarization-evoked release of noradrenaline from sympathetic neurones in rabbit carotid artery.

Journal: Basic & clinical pharmacology & toxicology 20050801

Title: Calcium has a permissive role in interleukin-1beta-induced c-jun N-terminal kinase activation in insulin-secreting cells.

Journal: Endocrinology 20050701

Title: Inhibition of T-type calcium channels protects neurons from delayed ischemia-induced damage.

Journal: Molecular pharmacology 20050701

Title: Developmental downregulation of low-voltage-activated Ca2+ channels in Cajal-Retzius cells of the mouse visual cortex.

Journal: The European journal of neuroscience 20050601

Title: Role of protein kinase C in Ca channel blocker-induced renal arteriolar dilation in spontaneously hypertensive rats--studies in the isolated perfused hydronephrotic kidney.

Journal: The Keio journal of medicine 20050601

Title: Voltage-dependent calcium channels.

Journal: General physiology and biophysics 20050601

Title: Inhibition of in vitro contractions of human myometrium by mibefradil, a T-type calcium channel blocker: support for a model using excitation-contraction coupling, and autocrine and paracrine signaling mechanisms.

Journal: Journal of the Society for Gynecologic Investigation 20050501

Title: Low-voltage-activated (T-type) calcium channels control proliferation of human pulmonary artery myocytes.

Journal: Circulation research 20050429

Title: T-type Ca2+ channels are involved in high glucose-induced rat neonatal cardiomyocyte proliferation.

Journal: Pediatric research 20050401

Title: Dendritic sodium spikelets and low-threshold calcium spikes in turtle olfactory bulb granule cells.

Journal: Journal of neurophysiology 20050301

Title: Pacemaker potentials generated by interstitial cells of Cajal in the murine intestine.

Journal: American journal of physiology. Cell physiology 20050301

Title: Differential blocking action of dihydropyridine Ca2+ antagonists on a T-type Ca2+ channel (alpha1G) expressed in Xenopus oocytes.

Journal: Journal of cardiovascular pharmacology 20050301

Title: Voltage-gated calcium channels play crucial roles in the glutamate-induced phase shifts of the rat suprachiasmatic circadian clock.

Journal: The European journal of neuroscience 20050301

Title: Clinical outcomes and management of mechanism-based inhibition of cytochrome P450 3A4.

Journal: Therapeutics and clinical risk management 20050301

Title: Low voltage-activated calcium channels in vascular smooth muscle: T-type channels and AVP-stimulated calcium spiking.

Journal: American journal of physiology. Heart and circulatory physiology 20050201

Title: Variation of T-type calcium channel protein expression affects cell division of cultured tumor cells.

Journal: Cell calcium 20050201

Title: Rapid stimulation causes electrical remodeling in cultured atrial myocytes.

Journal: Journal of molecular and cellular cardiology 20050201

Title: Synthesis and biological activity of 3,4-dihydroquinazolines for selective T-type Ca2+ channel blockers.

Journal: Bioorganic & medicinal chemistry letters 20050117

Title: Low threshold calcium currents in rat cerebellar Purkinje cell dendritic spines are mediated by T-type calcium channels.

Journal: The Journal of physiology 20050101

Title: Modulation of oral squamous cell carcinoma incidence in rats via diet and a novel calcium channel antagonist.

Journal: Toxicologic pathology 20050101

Title: Towards selective antagonists of T-type calcium channels: design, characterization and potential applications of NNC 55-0396.

Journal: Cardiovascular drug reviews 20050101

Title: The effects of mibefradil, a T-type Ca2+ channels blocker, on the renal dysfunction and injury caused by ischemia-reperfusion of the rat kidney.

Journal: Renal failure 20050101

Title: Spontaneous opening of T-type Ca2+ channels contributes to the irregular firing of dopamine neurons in neonatal rats.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20041208

Title: State-dependent mibefradil block of Na+ channels.

Journal: Molecular pharmacology 20041201

Title: The biochemical activation of T-type Ca2+ channels in HEK293 cells stably expressing alpha1G and Kir2.1 subunits.

Journal: Biochemical and biophysical research communications 20041105

Title: Comparative pharmacokinetic interaction profiles of pravastatin, simvastatin, and atorvastatin when coadministered with cytochrome P450 inhibitors.

Journal: The American journal of cardiology 20041101

Title: Role of voltage-gated calcium channels in potassium-stimulated aldosterone secretion from rat adrenal zona glomerulosa cells.

Journal: The Journal of steroid biochemistry and molecular biology 20041001

Title: Calcium channel blockers, either amlodipine or mibefradil, ameliorate renal injury in experimental diabetes.

Journal: Kidney international 20040901

Title: Michaelis-Menten kinetics under spatially constrained conditions: application to mibefradil pharmacokinetics.

Journal: Biophysical journal 20040901

Title: Ca2+ flux through voltage-gated channels with flow cessation in pulmonary microvascular endothelial cells.

Journal: Microcirculation (New York, N.Y. : 1994) 20040901

Title: Differential calcium regulation by hydrogen peroxide and superoxide in vascular smooth muscle cells from spontaneously hypertensive rats.

Journal: Journal of cardiovascular pharmacology 20040801

Title: Testosterone enhances calcium reabsorption by the kidney.

Journal: Molecular and cellular endocrinology 20040730

Title: The angiographic and clinical benefits of mibefradil in the coronary slow flow phenomenon.

Journal: Journal of the American College of Cardiology 20040707

Title: 3,4-Dihydroquinazoline derivatives as novel selective T-type Ca2+ channel blockers.

Journal: Bioorganic & medicinal chemistry letters 20040705

Title: Induction of apoptosis by the calcium antagonist mibefradil correlates with depolarization of the membrane potential and decreased integrin expression in human lens epithelial cells.

Journal: Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20040701

Title: Aldosterone enhances renal calcium reabsorption by two types of channels.

Journal: Kidney international 20040701

Title: Effects of calcium channel blockers on 'dynamic' and 'steady-state step' renal autoregulation.

Journal: American journal of physiology. Renal physiology 20040601

Title: The evaluation of the N-type channel blocking properties of cilnidipine and other voltage-dependent calcium antagonists.

Journal: Fundamental & clinical pharmacology 20040601

Title: Redox modulation of peripheral T-type Ca2+ channels in vivo: alteration of nerve injury-induced thermal hyperalgesia.

Journal: Pain 20040601

Title: Comparison of cardioprotective effects of mibefradil and ramipril in stroke-prone spontaneously hypertensive rats.

Journal: Acta pharmacologica Sinica 20040601

Title: Depolarization-induced calcium influx in rat mesenteric small arterioles is mediated exclusively via mibefradil-sensitive calcium channels.

Journal: British journal of pharmacology 20040601

Title: Characterization of T-type calcium current and its contribution to electrical activity in rabbit urethra.

Journal: American journal of physiology. Cell physiology 20040501

Title: Expression and differential cell distribution of low-threshold Ca(2+) channels in mammalian male germ cells and sperm.

Journal: FEBS letters 20040409

Title: NNC 55-0396 [(1S,2S)-2-(2-(N-[(3-benzimidazol-2-yl)propyl]-N-methylamino)ethyl)-6-fluoro-1,2,3,4-tetrahydro-1-isopropyl-2-naphtyl cyclopropanecarboxylate dihydrochloride]: a new selective inhibitor of T-type calcium channels.

Journal: The Journal of pharmacology and experimental therapeutics 20040401

Title: First pharmacophoric hypothesis for T-type calcium channel blockers.

Journal: Bioorganic & medicinal chemistry 20040401

Title: Identification of channels promoting calcium spikes and waves in HT1080 tumor cells: their apparent roles in cell motility and invasion.

Journal: Cancer research 20040401

Title: Pharmacology of recombinant low-voltage activated calcium channels.

Journal: Current drug targets. CNS and neurological disorders 20040401

Title: Integrating in vitro kinetic data from compounds exhibiting induction, reversible inhibition and mechanism-based inactivation: in vitro study design.

Journal: Current drug metabolism 20040401

Title: Distinct groups of multidrug resistance modulating agents are distinguished by competition of P-glycoprotein-specific antibodies.

Journal: Biochemical and biophysical research communications 20040319

Title: Mibefradil is more effective than verapamil for restoring post-ischemic function of isolated hearts of guinea pigs with acute renal failure.

Journal: European journal of pharmacology 20040319

Title: Developmental changes of intracellular Ca2+ transients in beating rat hearts.

Journal: American journal of physiology. Heart and circulatory physiology 20040301

Title: Combined blockade of AT1-receptors and ACE synergistically potentiates antihypertensive effects in SHR.

Journal: Journal of hypertension 20040301

Title: T-type calcium channels in the regulation of afferent and efferent arterioles in rats.

Journal: American journal of physiology. Renal physiology 20040201

Title: Functional expression of L- and T-type Ca2+ channels in murine HL-1 cells.

Journal: Journal of molecular and cellular cardiology 20040101

Title: Characterization of three types of calcium channel in the luminal membrane of the distal nephron.

Journal: Canadian journal of physiology and pharmacology 20040101

Title: Na(+) and Ca(2+) homeostasis pathways, cell death and protection after oxygen-glucose-deprivation in organotypic hippocampal slice cultures.

Journal: Neuroscience 20040101

Title: The sources and sequestration of Ca(2+) contributing to neuroeffector Ca(2+) transients in the mouse vas deferens.

Journal: The Journal of physiology 20031201

Title: Cellular mechanism for mibefradil-induced vasodilation of renal microcirculation: studies in the isolated perfused hydronephrotic kidney.

Journal: Journal of cardiovascular pharmacology 20031201

Title: Effects of imatinib mesylate (STI571, Glivec) on the pharmacokinetics of simvastatin, a cytochrome p450 3A4 substrate, in patients with chronic myeloid leukaemia.

Journal: British journal of cancer 20031117

Title: Mechanism of active repolarization of inhibitory junction potential in murine colon.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20031101

Title: The influence of calcium channel antagonists on isolated human distal radial arteries.

Journal: Journal of cardiovascular pharmacology 20031101

Title: [Drug interactions. Mechanisms and clinical relevance].

Journal: Der Internist 20031101

Title: Thalamic control of visceral nociception mediated by T-type Ca2+ channels.

Journal: Science (New York, N.Y.) 20031003

Title: Effect of mibefradil on CYP3A4 in vivo.

Journal: Journal of clinical pharmacology 20031001

Title: Generation and characterization of a cell line with inducible expression of Ca(v)3.2 (T-type) channels.

Journal: Assay and drug development technologies 20031001

Title: Reversal of experimental neuropathic pain by T-type calcium channel blockers.

Journal: Pain 20030901

Title: Cav3.1 (alpha1G) T-type Ca2+ channels mediate vaso-occlusion of sickled erythrocytes in lung microcirculation.

Journal: Circulation research 20030822

Title: Mechanisms of lateral inhibition in the olfactory bulb: efficiency and modulation of spike-evoked calcium influx into granule cells.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20030820

Title: Prediction of hERG potassium channel affinity by traditional and hologram qSAR methods.

Journal: Bioorganic & medicinal chemistry letters 20030818

Title: A T-type calcium channel required for normal function of a mammalian mechanoreceptor.

Journal: Nature neuroscience 20030701

Title: Effects of first and second generation calcium channel blockers on diastolic function of the failing hamster heart: relationship with coronary flow changes.

Journal: Journal of cardiovascular pharmacology 20030701

Title: Mibefradil: 'Has the baby been thrown out with the bath water?'.

Journal: American heart journal 20030701

Title: Comparison of in vitro P-glycoprotein screening assays: recommendations for their use in drug discovery.

Journal: Journal of medicinal chemistry 20030424

Title: Detection of proarrhythmia in the female rabbit heart: blinded validation.

Journal: Journal of cardiovascular electrophysiology 20030301

Title: New target molecules in the drug control of blood pressure and circulation.

Journal: Current drug targets. Cardiovascular & haematological disorders 20030301

Title: Regulation of ANP secretion by cardiac Na+/Ca2+ exchanger using a new controlled atrial model.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20030101

Title: Loss of T-type calcium current in sensory neurons of rats with neuropathic pain.

Journal: Anesthesiology 20030101

Title: Influence of R-type (Cav2.3) and t-type (Cav3.1-3.3) antagonists on nigral somatodendritic dopamine release measured by microdialysis.

Journal: Neuroscience 20030101

Title: Spontaneous regenerative activity in mammalian retinal bipolar cells: roles of multiple subtypes of voltage-dependent Ca2+ channels.

Journal: Visual neuroscience 20030101

Title: TGFbeta1 signaling via alphaVbeta6 integrin.

Journal: Molecular cancer 20030101

Title: Inhibition of collateral artery growth by mibefradil: possible role of volume-regulated chloride channels.

Journal: Endothelium : journal of endothelial cell research 20030101

Title: Atrial remodeling: evolving concepts.

Journal: Indian pacing and electrophysiology journal 20030101

Title: An ACTH- and ATP-regulated background K+ channel in adrenocortical cells is TREK-1.

Journal: The Journal of biological chemistry 20021220

Title: Role of T-type calcium channels in myogenic tone of skeletal muscle resistance arteries.

Journal: American journal of physiology. Heart and circulatory physiology 20021201

Title: Different effects of mibefradil and amlodipine on coronary vessels and during beta-adrenergic stimulation in conscious dogs.

Journal: Journal of cardiovascular pharmacology 20021201

Title: Selectivity of different calcium antagonists on T- and L-type calcium currents in guinea-pig ventricular myocytes.

Journal: Pharmacological research 20021201

Title: Effects of mibefradil on uterine contractility.

Journal: European journal of pharmacology 20021122

Title: Ca2+ entry via P/Q-type Ca2+ channels and the Na+/Ca2+ exchanger in rat and human neocortical synaptosomes.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20021101

Title: Involvement of T-type calcium channels in excitatory junction potentials in rat resistance mesenteric arteries.

Journal: British journal of pharmacology 20021101

Title: beta-Subunits: fine tuning of Ca(2+) channel block.

Journal: Trends in pharmacological sciences 20021101

Title: Involvement of T-type calcium channels in the mechanism of action of 5-HT in rat glomerulosa cells: a novel signaling pathway for the 5-HT7 receptor.

Journal: Endocrine research 20021101

Title: Calcium channel blockade limits transcriptional, translational and functional up-regulation of the cardiac calpain system after myocardial infarction.

Journal: European journal of pharmacology 20021018

Title: Mechanical and thermal antinociception in rats following systemic administration of mibefradil, a T-type calcium channel blocker.

Journal: Brain research 20021004

Title: T-channel-like pharmacological properties of high voltage-activated, nifedipine-insensitive Ca2+ currents in the rat terminal mesenteric artery.

Journal: British journal of pharmacology 20021001

Title: Modulation by mibefradil of the histamine-induced Ca2+ entry in human aortic endothelial cells.

Journal: Japanese journal of pharmacology 20021001

Title: Blood pressure response to antihypertensive agents related to baseline blood pressure.

Journal: Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20021001

Title: Local electric stimulation causes conducted calcium response in rat interlobular arteries.

Journal: American journal of physiology. Renal physiology 20020901

Title: Evidence that action potential generation is not the exclusive determinant to trigger spontaneous myogenic contraction of guinea-pig urinary bladder smooth muscle.

Journal: Acta physiologica Scandinavica 20020901

Title: Differential involvement of Ca(2+) channels in survival and neurite outgrowth of cultured embryonic cockroach brain neurons.

Journal: Journal of neurophysiology 20020901

Title: [Functional analysis of the alpha1G subunit of the T-type calcium channel in cellular proliferation].

Journal: Shi yan sheng wu xue bao 20020901

Title: Neuronal T-type alpha 1H calcium channels induce neuritogenesis and expression of high-voltage-activated calcium channels in the NG108-15 cell line.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20020815

Title: The Ca(2+) channel antagonists mibefradil and pimozide inhibit cell growth via different cytotoxic mechanisms.

Journal: Molecular pharmacology 20020801

Title: Fractal pharmacokinetics of the drug mibefradil in the liver.

Journal: Physical review. E, Statistical, nonlinear, and soft matter physics 20020801

Title: T-Type calcium channel alpha1G and alpha1H subunits in human retinoblastoma cells and their loss after differentiation.

Journal: Journal of neurophysiology 20020701

Title: Selective L-type, T-type, and nonspecific calcium-channel blockers for stable angina pectoris.

Journal: American heart journal 20020701

Title: Randomized comparison of T-type versus L-type calcium-channel blockade on exercise duration in stable angina: results of the Posicor Reduction of Ischemia During Exercise (PRIDE) trial.

Journal: American heart journal 20020701

Title: The role of T-type calcium channels in morphine analgesia, development of antinociceptive tolerance and dependence to morphine, and morphine abstinence syndrome.

Journal: Life sciences 20020628

Title: Voltage-dependent inward currents of interstitial cells of Cajal from murine colon and small intestine.

Journal: The Journal of physiology 20020615

Title: Identification of T-type alpha1H Ca2+ channels (Ca(v)3.2) in major pelvic ganglion neurons.

Journal: Journal of neurophysiology 20020601

Title: A post-marketing observational study to assess the safety of mibefradil in the community in England.

Journal: International journal of clinical pharmacology and therapeutics 20020601

Title: [T-type Ca2+ channels and cardiac pacemaker activity].

Journal: Clinical calcium 20020601

Title: Activation of 5-HT(7) receptor in rat glomerulosa cells is associated with an increase in adenylyl cyclase activity and calcium influx through T-type calcium channels.

Journal: Endocrinology 20020501

Title: Three-dimensional quantitative structure-activity relationships of inhibitors of P-glycoprotein.

Journal: Molecular pharmacology 20020501

Title: Mibefradil improves beta-adrenergic responsiveness and intracellular Ca(2+) handling in hypertrophied rat myocardium.

Journal: Experimental biology and medicine (Maywood, N.J.) 20020501

Title: Selective coupling of T-type calcium channels to SK potassium channels prevents intrinsic bursting in dopaminergic midbrain neurons.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20020501

Title: Pharmacological interactions of statins.

Journal: Atherosclerosis. Supplements 20020501

Title: Impaired mechanisms of leukocyte adhesion in vitro by the calcium channel antagonist mibefradil.

Journal: Cardiovascular drugs and therapy 20020501

Title: Impaired mechanisms of leukocyte adhesion in vitro by the calcium channel antagonist mibefradil.

Journal: Cardiovascular drugs and therapy 20020501

Title: Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.

Journal: The Journal of biological chemistry 20020419

Title: Antioxidant effect of T-type calcium channel blockers in gastric injury.

Journal: Digestive diseases and sciences 20020401

Title: Myopathy and rhabdomyolysis with lipid-lowering drugs.

Journal: Toxicology letters 20020310

Title: Single-channel pharmacology of mibefradil in human native T-type and recombinant Ca(v)3.2 calcium channels.

Journal: Molecular pharmacology 20020301

Title: Effect of nitric oxide synthase inhibitor N(omega) nitro-L-arginine methyl ester on relaxant responses to calcium channel antagonists in isolated aortic rings from Dahl normotensive and hypertensive rats.

Journal: Journal of cardiovascular pharmacology 20020301

Title: [Good and bad fortunes of drugs].

Journal: La Revue du praticien 20020301

Title: Angiotensin I-converting enzyme inhibition increases cardiac catecholamine content and reduces monoamine oxidase activity via an angiotensin type 1 receptor-mediated mechanism.

Journal: The Journal of pharmacology and experimental therapeutics 20020201

Title: FDA adverse event reports on statin-associated rhabdomyolysis.

Journal: The Annals of pharmacotherapy 20020201

Title: Acute effects of L- and T-type calcium channel antagonists on cardiovascular reflexes in conscious rabbits.

Journal: Clinical and experimental pharmacology & physiology 20020101

Title: Comparison of L-type and mixed L- and T-type calcium channel blockers on kidney injury caused by deoxycorticosterone-salt hypertension in rats.

Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 20011201

Title: Protective effect of T-type calcium channel blocker in histamine-induced paw inflammation in rat.

Journal: Pharmacological research 20011201

Title: Low-voltage-activated calcium channels are not involved in capacitation and biological response to progesterone in human sperm.

Journal: International journal of andrology 20011201

Title: Low threshold T-type calcium current in rat embryonic chromaffin cells.

Journal: The Journal of physiology 20011115

Title: State-dependent inhibition of inactivation-deficient Ca(V)1.2 and Ca(V)2.3 channels by mibefradil.

Journal: The Journal of membrane biology 20011115

Title: Divergent renal vasodilator action of L- and T-type calcium antagonists in vivo.

Journal: Journal of hypertension 20011101

Title: Evidence against an action of mibefradil at N-type voltage-operated calcium channels.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20011101

Title: T-type Ca(2+) channels mediate neurotransmitter release in retinal bipolar cells.

Journal: Neuron 20011011

Title: Divergent natriuretic action of calcium channel antagonists in mongrel dogs: renal haemodynamics as a determinant of natriuresis.

Journal: Clinical science (London, England : 1979) 20011001

Title: Torsades de pointes caused by Mibefradil.

Journal: European journal of heart failure 20011001

Title: Differential expression of T- and L-type voltage-dependent calcium channels in renal resistance vessels.

Journal: Circulation research 20010928

Title: Effect of T-type selective calcium antagonist on renal microcirculation: studies in the isolated perfused hydronephrotic kidney.

Journal: Hypertension (Dallas, Tex. : 1979) 20010901

Title: The triakontatetraneuropeptide TTN increases [CA2+]i in rat astrocytes through activation of peripheral-type benzodiazepine receptors.

Journal: Glia 20010801

Title: Selectivity of blocking of low- versus high-voltage activated calcium currents by the dihydropyridine derivatives Bay E5759 and Bay A4339 in neuroblastoma--glioma NG 108-15 cells.

Journal: Pharmacological research 20010801

Title: The underreporting of results and possible mechanisms of 'negative' drug trials in patients with chronic heart failure.

Journal: International journal of cardiology 20010801

Title: Redox modulation of T-type calcium channels in rat peripheral nociceptors.

Journal: Neuron 20010719

Title: L-type and T-type calcium channel blockade potentiate the analgesic effects of morphine and selective mu opioid agonist, but not to selective delta and kappa agonist at the level of the spinal cord in mice.

Journal: Pain 20010701

Title: Inhibition of lens epithelial cell adhesion by the calcium antagonist Mibefradil correlates with impaired integrin distribution and organization of the cytoskeleton.

Journal: Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20010701

Title: Novel voltage-dependent non-selective cation conductance in murine colonic myocytes.

Journal: The Journal of physiology 20010601

Title: Inhibition of T-type and L-type calcium channels by mibefradil: physiologic and pharmacologic bases of cardiovascular effects.

Journal: Journal of cardiovascular pharmacology 20010601

Title: Molecular identification of a TTX-sensitive Ca(2+) current.

Journal: American journal of physiology. Cell physiology 20010501

Title: Blocking swelling-activated chloride current inhibits mouse liver cell proliferation.

Journal: The Journal of physiology 20010501

Title: Comparative effects of selective T- and L-type calcium channel blockers in the remnant kidney model.

Journal: Hypertension (Dallas, Tex. : 1979) 20010501

Title: Inhibitory effects of verapamil and diltiazem on simvastatin metabolism in human liver microsomes.

Journal: British journal of clinical pharmacology 20010501

Title: Role of membrane depolarization and T-type Ca2+ channels in angiotensin II and K+ stimulated aldosterone secretion.

Journal: Molecular and cellular endocrinology 20010425

Title: Differential efficacy of L- and T-type calcium channel blockers in preventing tachycardia-induced atrial remodeling in dogs.

Journal: Cardiovascular research 20010301

Title: Comparison of sympathetic modulation induced by single oral doses of mibefradil, amlodipine, and nifedipine in healthy volunteers.

Journal: Clinical pharmacology and therapeutics 20010301

Title: Perceived benefit after participating in positive or negative/neutral heart failure trials: the patients' perspective.

Journal: European journal of heart failure 20010301

Title: Conducted vasoconstriction in rat mesenteric arterioles: role for dihydropyridine-insensitive Ca(2+) channels.

Journal: American journal of physiology. Heart and circulatory physiology 20010201

Title: Comparative effects of mibefradil and nifedipine gastrointestinal transport system on autonomic function in patients with mild to moderate essential hypertension.

Journal: Journal of hypertension 20010201

Title: Calcium channel blockade limits cardiac remodeling and improves cardiac function in myocardial infarction-induced heart failure in rats.

Journal: Journal of cardiovascular pharmacology 20010101

Title: Effects of the T-type calcium channel blockade with oral mibefradil on the electrophysiologic properties of the human heart.

Journal: Medical science monitor : international medical journal of experimental and clinical research 20010101

Title: Effects of mibefradil, a T- and L-type calcium channel blocker, on cardiac remodeling in the UM-X7.1 cardiomyopathic hamster.

Journal: Cardiovascular drugs and therapy 20010101

Title: The evaluation of pharmacologic therapy in humans: a brief summary of the drug evaluation process and guidelines for clinical trials as they related to women.

Journal: The journal of gender-specific medicine : JGSM : the official journal of the Partnership for Women's Health at Columbia 20010101

Title: Different effects of calcium antagonist and beta-blocker therapy on left-ventricular diastolic function in ischemic heart disease. A direct comparison of the impact of mibefradil and atenolol.

Journal: Cardiology 20010101

Title: Emerging role of drug interaction studies in drug development: the good, the bad, and the unknown.

Journal: Psychopharmacology bulletin 20010101

Title: Mibefradil block of cloned T-type calcium channels.

Journal: The Journal of pharmacology and experimental therapeutics 20001001

Title: Determinants of voltage-dependent inactivation affect Mibefradil block of calcium channels.

Journal: Neuropharmacology 20000101

Title: Combination of calcium channel blockers and beta blockers for patients with exercise-induced angina pectoris: a double-blind parallel-group comparison of different classes of calcium channel blockers. The Netherlands Working Group on Cardiovascular Research (WCN).

Journal: Angiology 19990601

Title: Structure and functional characterization of a novel human low-voltage activated calcium channel.

Journal: Journal of neurochemistry 19990201

Title: [Cardiology in 1997].

Journal: Casopis lekaru ceskych 19981005

Title: Mibefradil. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in the management of hypertension and angina pectoris.

Journal: Drugs 19971101

Title: Cardiovascular alterations in rat fetuses exposed to calcium channel blockers.

Journal: Reproductive toxicology (Elmsford, N.Y.) 19970101

Title: Comparative antihypertensive effectiveness of once-daily mibefradil and diltiazem CD. Mibefradil Hypertension Study Group.

Journal: Clinical therapeutics 19970101

Title: Comparative efficacy and tolerability of two long-acting calcium antagonists, mibefradil and amlodipine, in essential hypertension. Mibefradil Hypertension Study Group.

Journal: Clinical therapeutics 19970101

Title: Effect of antihypertensive treatment and N omega-nitro-L-arginine methyl ester on cardiovascular structure in deoxycorticosterone acetate-salt hypertensive rats.

Journal: Journal of hypertension 19961101

Title: Endothelin antagonism in end-organ damage of spontaneously hypertensive rats. Comparison with angiotensin-converting enzyme inhibition and calcium antagonism.

Journal: Hypertension (Dallas, Tex. : 1979) 19960901

Title: The novel calcium antagonist Ro 40-5967 limits myocardial infarct size in the dog.

Journal: Cardiovascular research 19941001

Title: Effect of calcium channel antagonists on cocaine-induced malignant arrhythmias: protection against ventricular fibrillation.

Journal: The Journal of pharmacology and experimental therapeutics 19930701

Title: Mehrke G, et al. The Ca(++)-channel blocker Ro 40-5967 blocks differently T-type and L-type Ca++ channels. J Pharmacol Exp Ther. 1994 Dec;271(3):1483-8.

Title: Brain KL, et al. The sources and sequestration of Ca(2+) contributing to neuroeffector Ca(2+) transients in the mouse vas deferens. J Physiol. 2003 Dec 1;553(Pt 2):627-35.

Title: Yu YF, et al. Protection of the cochlear hair cells in adult C57BL/6J mice by T-type calcium channel blockers. Exp Ther Med. 2016 Mar;11(3):1039-1044.

Title: Shiue SJ, et al. Chronic intrathecal infusion of T-type calcium channel blockers attenuates CaV3.2 upregulation in nerve-ligated rats. Acta Anaesthesiol Taiwan. 2016 Oct 17. pii: S1875-4597(16)30071-6.