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119425-90-0,MFCD07781421
Catalog No.:AA000INZ

119425-90-0 | Loureirin B

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1mg
≥98%
in stock  
$69.00   $48.00
- +
5mg
≥98%
in stock  
$318.00   $222.00
- +
10mg
≥98%
in stock  
$562.00   $393.00
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25mg
≥98%
in stock  
$1,153.00   $807.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA000INZ
Chemical Name:
Loureirin B
CAS Number:
119425-90-0
Molecular Formula:
C18H20O5
Molecular Weight:
316.3484
MDL Number:
MFCD07781421
SMILES:
COc1cc(OC)cc(c1CCC(=O)c1ccc(cc1)O)OC
Properties
Computed Properties
 
Complexity:
350  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
23  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
7  
XLogP3:
3.1  

Literature

Title: [Simultaneous determination of five active components in resina draconis and its extract by HPLC].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20120401

Title: Simultaneous quantification of loureirin A and loureirin B in rat urine, feces, and bile by HPLC-MS/MS method and its application to excretion study.

Journal: Analytical and bioanalytical chemistry 20110501

Title: Production of dragon's blood in Dracaena cochinchinensis plants by inoculation of Fusarium proliferatum.

Journal: Plant science : an international journal of experimental plant biology 20110201

Title: A sensitive LC-MS/MS method to quantify loureirin B in rat plasma with application to preclinical pharmacokinetic studies.

Journal: Journal of pharmaceutical and biomedical analysis 20091205

Title: Slow rise of intracellular Ca(2+) concentration in rat primary sensory neurons triggered by loureirin B.

Journal: Sheng li xue bao : [Acta physiologica Sinica] 20090425

Title: Material basis for inhibition of Dragon's Blood on evoked discharges of wide dynamic range neurons in spinal dorsal horn of rats.

Journal: Science in China. Series C, Life sciences 20081101

Title: Modulation of dragon's blood on tetrodotoxin-resistant sodium currents in dorsal root ganglion neurons and identification of its material basis for efficacy.

Journal: Science in China. Series C, Life sciences 20060601

Title: Sha Y, et al. Loureirin B promotes insulin secretion through inhibition of KATP channel and influx of intracellular calcium. J Cell Biochem. 2017 Aug 17.

Title: He T, et al. Loureirin B Inhibits Hypertrophic Scar Formation via Inhibition of the TGF-β1-ERK/JNK Pathway. Cell Physiol Biochem. 2015;37(2):666-76.

Title: Bai X, et al. Loureirin B inhibits fibroblast proliferation and extracellular matrix deposition in hypertrophic scar via TGF-β/Smad pathway. Exp Dermatol. 2015 May;24(5):355-60.

Title: Yu Jiang, et al. Bioactivity-Guided Fractionation of the Traditional Chinese Medicine Resina Draconis Reveals Loureirin B as a PAI-1 Inhibitor. Evidence-Based Complementary and Alternative Medicine

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