Title: Discovery of mammalian target of rapamycin (mTOR) kinase inhibitor CC-223.
Journal: Journal of medicinal chemistry 20150709
Title: Discovery and SAR exploration of a novel series of imidazo[4,5-b]pyrazin-2-ones as potent and selective mTOR kinase inhibitors.
Journal: Bioorganic & medicinal chemistry letters 20111115
Title: Mortensen DS, et al. CC-223, a Potent and Selective Inhibitor of mTOR Kinase: In Vitro and In Vivo Characterization. Mol Cancer Ther. 2015 Jun;14(6):1295-305.
