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122841-12-7,MFCD01940015
Catalog No.:AA000JI8

122841-12-7 | Cefoselis sulfate

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
95%
in stock  
$35.00   $25.00
- +
5mg
≥98%
in stock  
$98.00   $68.00
- +
10mg
95%
in stock  
$158.00   $110.00
- +
25mg
≥98%
in stock  
$307.00   $215.00
- +
50mg
95%
in stock  
$454.00   $318.00
- +
100mg
95%
in stock  
$769.00   $538.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA000JI8
Chemical Name:
Cefoselis sulfate
CAS Number:
122841-12-7
Molecular Formula:
C19H24N8O10S3
Molecular Weight:
620.6365
MDL Number:
MFCD01940015
SMILES:
OS(=O)(=O)O.OCCn1c(=N)ccn1CC1=C(C(=O)O)N2[C@H](SC1)[C@@H](C2=O)NC(=O)/C(=N\OC)/c1csc(n1)N
Properties
Computed Properties
 
Complexity:
1100  
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
2  
Defined Bond Stereocenter Count:
1  
Heavy Atom Count:
40  
Hydrogen Bond Acceptor Count:
17  
Hydrogen Bond Donor Count:
7  
Rotatable Bond Count:
9  

Literature

Title: Human organic anion transporter hOAT3 is a potent transporter of cephalosporin antibiotics, in comparison with hOAT1.

Journal: Biochemical pharmacology 20051001

Title: Cefoselis, a beta-lactam antibiotic, easily penetrates the blood-brain barrier and causes seizure independently by glutamate release.

Journal: Journal of neural transmission (Vienna, Austria : 1996) 20041201

Title: Intracerebroventricular injection of the antibiotic cefoselis produces convulsion in mice via inhibition of GABA receptors.

Journal: Pharmacology, biochemistry, and behavior 20021201

Title: Antimicrobial susceptibility of major pathogens of orofacial odontogenic infections to 11 beta-lactam antibiotics.

Journal: Oral microbiology and immunology 20021001

Title: The beta-lactam antibiotics, penicillin-G and cefoselis have different mechanisms and sites of action at GABA(A) receptors.

Journal: British journal of pharmacology 20020101

Title: Effect of experimental renal failure on the pharmacodynamics of cefoselis-induced seizures in rats.

Journal: Biological & pharmaceutical bulletin 20010901

Title: K Ohtaki, et al. Cefoselis, a beta-lactam antibiotic, easily penetrates the blood-brain barrier and causes seizure independently by glutamate release. J Neural Transm (Vienna). 2004 Dec;111(12):1523-35.

Title: ZHU, D., et al., In vitro activities of cefoselis compared to β-lactams and other antibacterial agents aganst gram-positive and gram-negative clinical isolates. Chinese Journal of Infection and Chemotherapy, 2011. 4: p. 002.

Title: King, A., L. Bethune, and I. Phillips, The Comparative In Vitro Activity of FK-037 (Cefoselis), a New Broad-Spectrum Cephalosporin. Clin Microbiol Infect, 1995. 1(1): p. 13-17.

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