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Home Other Building Blocks 1229236-86-5
1229236-86-5,MFCD20482143
Catalog No.:AA000JPL

1229236-86-5 | Gandotinib

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
≥98%
in stock  
$89.00   $62.00
- +
5mg
98%
in stock  
$132.00   $93.00
- +
10mg
≥98%
in stock  
$250.00   $175.00
- +
25mg
98%
in stock  
$275.00   $193.00
- +
100mg
98%
in stock  
$743.00   $520.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA000JPL
Chemical Name:
Gandotinib
CAS Number:
1229236-86-5
Molecular Formula:
C23H25ClFN7O
Molecular Weight:
469.9423
MDL Number:
MFCD20482143
SMILES:
Clc1ccc(c(c1)F)Cc1c(C)nc2n1nc(Nc1n[nH]c(c1)C)cc2CN1CCOCC1
Properties
Computed Properties
 
Complexity:
644  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
33  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
6  
XLogP3:
3.8  

Literature

Title: Differences in gene expression and alterations in cell cycle of acute myeloid leukemia cell lines after treatment with JAK inhibitors.

Journal: European journal of pharmacology 20151015

Title: Discovery and characterization of LY2784544, a small-molecule tyrosine kinase inhibitor of JAK2V617F.

Journal: Blood cancer journal 20130401

Title: Ma L, et al. Discovery and characterization of LY2784544, a small-molecule tyrosine kinase inhibitor of JAK2V617F. Blood Cancer J. 2013, 3, e109.

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