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123171-59-5,MFCD06795759
Catalog No.:AA000K10

123171-59-5 | Cefepime Dihydrochloride Monohydrate

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Purity
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1g
97%(HPLC)
in stock  
$35.00   $25.00
- +
5g
84 - 90% (Assay as Cefepime)
in stock  
$124.00   $87.00
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25g
97%(HPLC)
in stock  
$569.00   $398.00
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100g
97%(HPLC)
in stock  
$1,966.00   $1,376.00
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250g
97%(HPLC)
in stock  
$4,351.00   $3,046.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA000K10
Chemical Name:
Cefepime Dihydrochloride Monohydrate
CAS Number:
123171-59-5
Molecular Formula:
C19H28Cl2N6O6S2
Molecular Weight:
571.4982
MDL Number:
MFCD06795759
SMILES:
CO/N=C(/c1csc(n1)N)\C(=O)N[C@@H]1C(=O)N2[C@@H]1SCC(=C2C(=O)O)C[N+]1(C)CCCC1.O.Cl.[Cl-]
Properties
Computed Properties
 
Complexity:
874  
Covalently-Bonded Unit Count:
4  
Defined Atom Stereocenter Count:
2  
Defined Bond Stereocenter Count:
1  
Heavy Atom Count:
35  
Hydrogen Bond Acceptor Count:
12  
Hydrogen Bond Donor Count:
5  
Rotatable Bond Count:
7  

Literature

Title: Underdosing of common antibiotics for obese patients in the ED.

Journal: The American journal of emergency medicine 20120901

Title: Extended-spectrum β-lactamase producers reported as susceptible to piperacillin-tazobactam, cefepime, and cefuroxime in the era of lowered breakpoints and no confirmatory tests.

Journal: Infection control and hospital epidemiology 20120801

Title: AmpC β-lactamases in nosocomial isolates of Klebsiella pneumoniae from India.

Journal: The Indian journal of medical research 20120801

Title: Population pharmacokinetics of four β-lactams in critically ill septic patients comedicated with amikacin.

Journal: Clinical biochemistry 20120701

Title: Cefepime: a rare cause of encephalopathy.

Journal: Internal medicine journal 20120601

Title: Blood and CSF monitoring of cefepime-induced neurotoxicity: nine case reports.

Journal: The Journal of antimicrobial chemotherapy 20120501

Title: Cefepime for Gram-negative bacteremia in long-term hemodialysis: a single-center experience.

Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 20120501

Title: [Marked reactive plasmacytosis accompanied by drug eruption in a patient with aplastic anemia].

Journal: [Rinsho ketsueki] The Japanese journal of clinical hematology 20120501

Title: Rates and appropriateness of antimicrobial prescribing at an academic children's hospital, 2007-2010.

Journal: Infection control and hospital epidemiology 20120401

Title: Efficacy of doripenem against Escherichia coli and Klebsiella pneumoniae in experimental meningitis.

Journal: The Journal of antimicrobial chemotherapy 20120301

Title: Cefepime dosing in the morbidly obese patient population.

Journal: Obesity surgery 20120301

Title: Genetic characterization of an extended-spectrum AmpC cephalosporinase with hydrolysing activity against fourth-generation cephalosporins in a clinical isolate of Enterobacter aerogenes selected in vivo.

Journal: The Journal of antimicrobial chemotherapy 20120101

Title: Infection from an exfoliating primary tooth in a child with severe neutropenia: a case report.

Journal: Pediatric dentistry 20120101

Title: Role of the two component signal transduction system CpxAR in conferring cefepime and chloramphenicol resistance in Klebsiella pneumoniae NTUH-K2044.

Journal: PloS one 20120101

Title: Animal model methodology: immunocompetent or leucopenic rats, which is the best? Results from a model of experimental pneumonia due to derepressed cephalosporinase-producing Enterobacter cloacae.

Journal: Chemotherapy 20120101

Title: [Resistance to extended-spectrum cephalosporins in non-inducible AmpC enterobacteria: evaluation of the new MIC breakpoints].

Journal: Revista Argentina de microbiologia 20120101

Title: [Severely abnormal electroencephalogram in two patients who were treated with cefepime].

Journal: Rinsho shinkeigaku = Clinical neurology 20120101

Title: The ecology of antibiotic use in the ICU: homogeneous prescribing of cefepime but not tazocin selects for antibiotic resistant infection.

Journal: PloS one 20120101

Title: [Microbiological monitoring in therapy of patients with iatrogenic esophageotracheal fistula].

Journal: Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20120101

Title: Antimicrobial susceptibility pattern and distribution of exoU and exoS in clinical isolates of Pseudomonas aeruginosa at a Malaysian hospital.

Journal: The Southeast Asian journal of tropical medicine and public health 20120101

Title: Mechanisms of resistance in clinical isolates of Pseudomonas aeruginosa less susceptible to cefepime than to ceftazidime.

Journal: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20111201

Title: Effect of spacer sequences between bla(CTX-M) and ISEcp1 on bla(CTX-M) expression.

Journal: Journal of medical microbiology 20111201

Title: Cefepime-associated thrombocytopenia in a critically ill patient.

Journal: International journal of clinical pharmacy 20111201

Title: Antibiotic stability in commercial peritoneal dialysis solutions: influence of formulation, storage and duration.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20111001

Title: Cefepime neurotoxicity despite renal adjusted dosing.

Journal: Scandinavian journal of infectious diseases 20111001

Title: Continuous epileptiform discharges in patients treated with cefepime or meropenem.

Journal: Archives of neurology 20111001

Title: Inhibitory effects of various essential oils and individual components against extended-spectrum beta-lactamase (ESBL) produced by Klebsiella pneumoniae and their chemical compositions.

Journal: Journal of food science 20111001

Title: [Current clinical practice in the treatment of febrile neutropenia (FN)].

Journal: The Japanese journal of antibiotics 20111001

Title: Acute kidney injury from pyelonephritis in an elderly man: case report.

Journal: International urology and nephrology 20110901

Title: False extended-spectrum {beta}-lactamase phenotype in clinical isolates of Escherichia coli associated with increased expression of OXA-1 or TEM-1 penicillinases and loss of porins.

Journal: The Journal of antimicrobial chemotherapy 20110901

Title: Antimicrobial resistance and prevalence of virulence factor genes in fecal Escherichia coli of Holstein calves fed milk with and without antimicrobials.

Journal: Journal of dairy science 20110901

Title: Neurotoxicity due to cefepime in patients on maintenance hemodialysis.

Journal: Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia 20110901

Title: Clinical and electroencephalographic assessment of cefepime during treatment of nosocomial infections in neurological patients.

Journal: Central nervous system agents in medicinal chemistry 20110901

Title: [Assessment of efficacies of imipenem, cefoperazone-sulbactam and cefepime in rats with experimental thigh abscess model with multidrug resistant and susceptible Acinetobacter baumannii strains].

Journal: Mikrobiyoloji bulteni 20110701

Title: The importance of pharmacokinetic consultation of cefepime treatment for Pseudomonas aeruginosa bacteremia: a case report of severe thermal burn injury.

Journal: Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 20110601

Title: Molecular analysis of antimicrobial agent translocation through the membrane porin BpsOmp38 from an ultraresistant Burkholderia pseudomallei strain.

Journal: Biochimica et biophysica acta 20110601

Title: Investigating the impact of the definition of previous antibiotic exposure related to isolation of extended spectrum β-lactamase-producing Klebsiella pneumoniae.

Journal: American journal of infection control 20110601

Title: Is cefepime safe for clinical use? A Bayesian viewpoint.

Journal: The Journal of antimicrobial chemotherapy 20110601

Title: Cefepime-resistant Pseudomonas aeruginosa.

Journal: Emerging infectious diseases 20110601

Title: Cefepime effectiveness in Gram-negative bloodstream infections.

Journal: The Journal of antimicrobial chemotherapy 20110501

Title: Septic elbow in the setting of neuropathic joint as the initial presentation of a cervical syrinx.

Journal: Orthopedics 20110411

Title: Outpatient treatment with intravenous antimicrobial therapy and oral levofloxacin in patients with febrile neutropenia and hematological malignancies.

Journal: Annals of hematology 20110401

Title: Extragenitourinary malakoplakia in a patient with myeloma clinically mimicking extramedullary myelomatous disease.

Journal: Human pathology 20110401

Title: Antibiotic resistance in Pseudomonas aeruginosa related to quinolone formulary changes: an interrupted time series analysis.

Journal: Infection control and hospital epidemiology 20110401

Title: Rare case of large double perforated anterior mitral leaflet pseudoaneurysm in a patient with aortic valve endocarditis.

Journal: Ultraschall in der Medizin (Stuttgart, Germany : 1980) 20110401

Title: Melioidosis presenting as sepsis syndrome: a case report.

Journal: International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases 20110301

Title: Systemic lupus erythematosus induced by cefepime.

Journal: Journal of the American Academy of Dermatology 20110301

Title: Impact of evaluating antibiotic concentrations in abdominal abscesses percutaneously drained.

Journal: American journal of surgery 20110301

Title: Effect of a cholesterol rich diet, recurrent infection and possible treatment modalities on the pulmonary vascular system: an experimental study.

Journal: The West Indian medical journal 20110301

Title: Eradication of Pseudomonas aeruginosa in an adult patient with cystic fibrosis.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20110215

Title: Cefepime-related encephalopathy in peritoneal dialysis patients.

Journal: Journal of the Chinese Medical Association : JCMA 20110201

Title: Steady-state pharmacokinetics and pharmacodynamics of cefepime administered by prolonged infusion in hospitalised patients.

Journal: International journal of antimicrobial agents 20110101

Title: Stability of cefepime in aqueous eye drops.

Journal: Die Pharmazie 20110101

Title: Cefepime resistance and associated risk factors among Escherichia coli strains isolated from clinical specimens.

Journal: Chemotherapy 20110101

Title: Cefepime versus extended spectrum β-lactamase-producing Enterobacteriaceae.

Journal: The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases 20110101

Title: [Application of preparation quadrocef in the treatment of surgical sepsis].

Journal: Klinichna khirurhiia 20110101

Title: The impact of a nationwide antibiotic restriction program on antibiotic usage and resistance against nosocomial pathogens in Turkey.

Journal: International journal of medical sciences 20110101

Title: Recommended β-lactam regimens are inadequate in septic patients treated with continuous renal replacement therapy.

Journal: Critical care (London, England) 20110101

Title: Comparison of the boronic acid disk potentiation test and cefepime-clavulanic acid method for the detection of ESBL among AmpC-producing Enterobacteriaceae.

Journal: Indian journal of medical microbiology 20110101

Title: [Actual aspects of sepsis].

Journal: Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20110101

Title: Antibiotics in critically ill patients: a systematic review of the pharmacokinetics of β-lactams.

Journal: Critical care (London, England) 20110101

Title: [Review of the effectiveness of an empirical antibiotic therapy in suspected ventilator-associated pneumonia].

Journal: Anestezjologia intensywna terapia 20110101

Title: A prospective study of cefepime versus ticarcilline/clavulanate as empirical treatment of febrile neutropenia in lymphoma patients.

Journal: JPMA. The Journal of the Pakistan Medical Association 20110101

Title: A simple and rapid dispersive liquid-liquid microextraction method followed by GC-FID for determination of N-methylpyrrolidine in cefepime.

Journal: Journal of separation science 20101201

Title: Meta-analysis of a possible signal of increased mortality associated with cefepime use.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20101201

Title: [Cefepime versus piperacillin/tazobactam with or without amikacin in the treatment of febrile hematological and oncological neutropenic patients in an internal medicine ward].

Journal: Harefuah 20101201

Title: Anti-pseudomonal beta-lactams for the initial, empirical, treatment of febrile neutropenia: comparison of beta-lactams.

Journal: The Cochrane database of systematic reviews 20101110

Title: Validation of capillary electrophoresis method for determination of N-methylpyrrolidine in cefepime for injection.

Journal: Journal of chromatographic science 20101101

Title: The molecular characteristics of cefepime-susceptible Escherichia coli and Klebsiella spp. isolates with a positive β-lactamase screening test result but negative confirmation.

Journal: European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 20101001

Title: Asymptomatic catheter related Rhizobium radiobacter infection in a haploidentical hemapoetic stem cell recipient.

Journal: Journal of infection in developing countries 20100903

Title: Efficacy and safety of cefepime in pediatric patients: a systematic review and meta-analysis.

Journal: The Journal of pediatrics 20100901

Title: Cefepime-resistant Gram-negative bacteremia in febrile neutropenic patients with hematological malignancies.

Journal: International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases 20100901

Title: Biotic and abiotic degradation of four cephalosporin antibiotics in a lake surface water and sediment.

Journal: Chemosphere 20100901

Title: Role of changes in the L3 loop of the active site in the evolution of enzymatic activity of VIM-type metallo-beta-lactamases.

Journal: The Journal of antimicrobial chemotherapy 20100901

Title: High-performance liquid chromatographic determination and pharmacokinetic study of cefepime in goat plasma and milk after pre-column derivatization with Hg(I).

Journal: Journal of separation science 20100901

Title: [Multiple brain abscesses complicating Enterobacter cloacae sepsis in a premature infant].

Journal: Archives de pediatrie : organe officiel de la Societe francaise de pediatrie 20100901

Title: Meta-analysis of a possible signal of increased mortality associated with cefepime use.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20100815

Title: Cefepime and death: reality to the rescue.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20100815

Title: Maternal and fetal blood levels of moxifloxacin, levofloxacin, cefepime and cefoperazone.

Journal: International journal of antimicrobial agents 20100801

Title: Cefepime and mortality: a real issue?

Journal: Scandinavian journal of infectious diseases 20100701

Title: Efficacy of cefepime therapy for Enterobacter bacteraemia, with special emphasis on febrile neutropenic patients.

Journal: Scandinavian journal of infectious diseases 20100701

Title: Lactation stage influences drug milk-to-serum values and neonatal exposure risk.

Journal: International journal of toxicology 20100701

Title: Chryseobacterium indologenes bacteremia in an infant.

Journal: International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases 20100601

Title: The novel sensitive and high throughput determination of cefepime in mouse plasma by SCX-LC/MS/MS method following off-line microElution 96-well solid-phase extraction to support systemic antibiotic programs.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20100601

Title: Antistaphylococcal activities of telavancin tested alone and in combination by time-kill assay.

Journal: Antimicrobial agents and chemotherapy 20100501

Title: Excess mortality related to cefepime.

Journal: The Lancet. Infectious diseases 20100501

Title: A recent evaluation of empirical cephalosporin treatment and antibiotic resistance of changing bacterial profiles in spontaneous bacterial peritonitis.

Journal: Digestive diseases and sciences 20100401

Title: Clinical efficacy and safety of cefepime in febrile neutropenic patients with lung cancer.

Journal: Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 20100401

Title: Synergy of fosfomycin with other antibiotics for Gram-positive and Gram-negative bacteria.

Journal: European journal of clinical pharmacology 20100401

Title: Low-dose beta-lactam plus amikacin in febrile neutropenia: cefepime vs. piperacillin/tazobactam, a randomized trial.

Journal: European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 20100401

Title: Early endovascular coiling of posterior communicating artery saccular aneurysm in the setting of Staphylococcus bacteremia: case report and review of the literature.

Journal: Neurosurgery 20100401

Title: Acinetobacter endocarditis presenting as a large right atrial mass: an atypical presentation.

Journal: Echocardiography (Mount Kisco, N.Y.) 20100401

Title: Quantitative assessment of combination antimicrobial therapy against multidrug-resistant bacteria in a murine pneumonia model.

Journal: The Journal of infectious diseases 20100315

Title: Pharmacodynamic-based clinical pathway for empiric antibiotic choice in patients with ventilator-associated pneumonia.

Journal: Journal of critical care 20100301

Title: Optimal cefepime and meropenem dosing for ventilator-associated pneumonia patients with reduced renal function: an update to our clinical pathway.

Journal: Journal of critical care 20100301

Title: Cefepime: an underrecognized cause of nonconvulsive status epilepticus.

Journal: Journal of hospital medicine 20100301

Title: Prolonged bacteraemia caused by VIM-1 metallo-beta-lactamase-producing Proteus mirabilis: first report from Italy.

Journal: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20100201

Title: [Change of ESBLs-KPN and ESBLs-ECO after antimicrobial intervention].

Journal: Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20100201

Title: [Comparative activity of ertapenem against extended-spectrum beta-lactamase-producing or plasmid-mediated AmpC beta-lactamase-producing Klebsiella pneumoniae].

Journal: Enfermedades infecciosas y microbiologia clinica 20100101

Title: A case of severe cefepime-related neutropenia in a 15-year-old patient.

Journal: Scandinavian journal of infectious diseases 20100101

Title: Prospective monitoring of cefepime in intensive care unit adult patients.

Journal: Critical care (London, England) 20100101

Title: Insufficient β-lactam concentrations in the early phase of severe sepsis and septic shock.

Journal: Critical care (London, England) 20100101

Title: Nosocomial transmission of Cupriavidus pauculus during extracorporeal membrane oxygenation.

Journal: ASAIO journal (American Society for Artificial Internal Organs : 1992) 20100101

Title: Emergence of fluoroquinolone-resistant Streptococcus pneumoniae in Lebanon: a report of three cases.

Journal: Journal of infection and public health 20100101

Title: Identification and characterization of new degradation products of cefepime dihydrochloride monohydrate drug substance during stress stability studies.

Journal: Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20100101

Title: A novel intraperitoneal cefepime regime based on pharmacokinetic modeling to treat CAPD peritonitis.

Journal: Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis 20100101

Title: Outbreaks of imipenem resistant Acinetobacter baumannii producing OXA-23 beta-lactamase in a tertiary care hospital in Korea.

Journal: Yonsei medical journal 20091231

Title: Influence of plasma exchange on the disposition of the fourth generation cephalosporin cefepime.

Journal: Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners 20091201

Title: Use of the cefepime-clavulanate ESBL Etest for detection of extended-spectrum beta-lactamases in AmpC co-producing bacteria.

Journal: Journal of infection in developing countries 20091121

Title: Simultaneous multiresponse optimization of an HPLC method to separate seven cephalosporins in plasma and amniotic fluid: application to validation and quantification of cefepime, cefixime and cefoperazone.

Journal: Talanta 20091115

Title: Cefepime and mortality in pediatric acute myelogenous leukemia: a retrospective cohort study.

Journal: The Pediatric infectious disease journal 20091101

Title: Piperacillin/tazobactam versus cefepime for the empirical treatment of pediatric cancer patients with neutropenia and fever: a randomized and open-label study.

Journal: Pediatric blood & cancer 20091001

Title: Cefepime and mortality.

Journal: The Lancet. Infectious diseases 20091001

Title: Mortality associated with cefepime therapy among neutropenic patients.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20090915

Title: In vitro activity of ceftobiprole against Acinetobacter baumannii clinical isolates.

Journal: International journal of antimicrobial agents 20090901

Title: Fixed-dose combination of cefepime plus amikacin (potentox) inhibits pneumonia infection.

Journal: Experimental lung research 20090901

Title: Cefepime and all-cause mortality.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20090815

Title: Evaluation of single-dose pharmacokinetics of cefepime in healthy bull camels (Camelus dromedaries).

Journal: Journal of veterinary pharmacology and therapeutics 20090801

Title: Cefepime-associated status epilepticus in an ICU patient with renal failure.

Journal: Journal of chemotherapy (Florence, Italy) 20090801

Title: Assessment of an alternative meropenem dosing strategy compared with imipenem-cilastatin or traditional meropenem dosing after cefepime failure or intolerance in adults with neutropenic fever.

Journal: Pharmacotherapy 20090801

Title: An improved ion chromatographic method for fast and sensitive determination of N-methylpyrrolidine in cefepime hydrochloride.

Journal: Journal of chromatographic science 20090801

Title: Agranulocytosis following phenytoin-induced hypersensitivity syndrome.

Journal: Brain & development 20090601

Title: Overproduction of K1 enzyme in Klebsiella oxytoca clinical isolates against ceftazidime, cefepime and ceftobiprole.

Journal: Journal of chemotherapy (Florence, Italy) 20090601

Title: Determination of total cefozopran concentrations in human peritoneal fluid by HPLC with cefepime as an internal standard: Comparative pharmacokinetics in the fluid and plasma.

Journal: Journal of pharmaceutical and biomedical analysis 20090501

Title: Comparison of different methods of determining beta-lactam susceptibility in clinical strains of Pseudomonas aeruginosa.

Journal: Journal of medical microbiology 20090501

Title: Failure of cefepime therapy in neutropenic patients with extended-spectrum beta-lactamase-producing Gram-negative bacteraemia.

Journal: International journal of antimicrobial agents 20090401

Title: Cefepime monotherapy is as effective as ceftriaxone plus amikacin in pediatric patients with cancer and high-risk febrile neutropenia in a randomized comparison.

Journal: Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi 20090401

Title: [Backache with fever and shivering. Dangerous epidural abscess].

Journal: MMW Fortschritte der Medizin 20090312

Title: Characterization of the charge variants of L2 beta-lactamase in Stenotrophomonas maltophilia.

Journal: Journal of medical microbiology 20090301

Title: Surveillance of intrahospital infections at the clinic for gynaecology and obstetrics.

Journal: Bosnian journal of basic medical sciences 20090201

Title: Effects of an alternative cefepime dosing strategy in pulmonary and bloodstream infections caused by Enterobacter spp, Citrobacter freundii, and Pseudomonas aeruginosa: a single-center, open-label, prospective, observational study.

Journal: Clinical therapeutics 20090201

Title: Cefepime-induced nonconvulsive status epilepticus: case report and review.

Journal: Neurocritical care 20090101

Title: Efficacy and safety of cefepime.

Journal: The Lancet. Infectious diseases 20090101

Title: Why the confusion?

Journal: Journal of the Mississippi State Medical Association 20090101

Title: Cefepime and amikacin as empirical therapy in patients with febrile neutropaenia: a single-centre phase II prospective survey.

Journal: Acta clinica Belgica 20090101

Title: [Cefepime-induced encephalopathy in patients with renal failure].

Journal: Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20090101

Title: [Impact of administration rate parameter in toxicity test].

Journal: Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20090101

Title: 'Aseptic pneumonitis'.

Journal: Internal medicine (Tokyo, Japan) 20090101

Title: Post-antibiotic effect of levofloxacin and tobramycin alone or in combination with cefepime against Pseudomonas aeruginosa.

Journal: Chemotherapy 20090101

Title: [Cefepim in empiric therapy of ventilator-associated pneumonia].

Journal: Anestezjologia intensywna terapia 20090101

Title: Cefepime: a reappraisal in an era of increasing antimicrobial resistance.

Journal: Expert review of anti-infective therapy 20081201

Title: Dose related effect of systemic antibiotics in prevention of postoperative intra-abdominal adhesion formation in experimental animals.

Journal: Journal of the Egyptian Society of Parasitology 20081201

Title: Fever, hip pain, and headache in a 12-year-old girl.

Journal: Clinical pediatrics 20081101

Title: Cefepime-induced neutropenia in a teenager.

Journal: Pediatric blood & cancer 20081101

Title: Antimicrobial activity of cefepime and rifampicin in cerebrospinal fluid in vitro.

Journal: The Journal of antimicrobial chemotherapy 20081101

Title: Cefepime overdosage with neurotoxicity recovered by high-volume haemofiltration.

Journal: The Journal of antimicrobial chemotherapy 20081001

Title: Emergence of a cefepime- and cefpirome-resistant Citrobacter freundii clinical isolate harbouring a novel chromosomally encoded AmpC beta-lactamase, CMY-37.

Journal: International journal of antimicrobial agents 20080901

Title: Fixed dose combination of cefepime plus amikacin prevent oxidative stress in liver of Mus musculus mice.

Journal: Current clinical pharmacology 20080901

Title: Evaluation of sensitivity of different organisms to cefepime and tazobactum (megapime XP) in comparison to cefepime and ceftazidime.

Journal: Journal of the Indian Medical Association 20080901

Title: Bacterial resistance surveillance in China: a report from Mohnarin 2004-2005.

Journal: European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 20080801

Title: An in vivo-in vitro study of cefepime and cefazolin dialytic clearance during high-flux hemodialysis.

Journal: Pharmacotherapy 20080801

Title: Pharmacokinetics of fusidic acid and cefepime in heart tissues: implications for a role in surgical prophylaxis.

Journal: Journal of chemotherapy (Florence, Italy) 20080801

Title: Cefepime/clindamycin vs. ceftriaxone/clindamycin for the empiric treatment of poisoned patients with aspiration pneumonia.

Journal: Acta bio-medica : Atenei Parmensis 20080801

Title: The safety of cefepime in the treatment of infection.

Journal: Expert opinion on drug safety 20080701

Title: Population pharmacokinetics of cefepime in neonates with severe nosocomial infections.

Journal: Journal of clinical pharmacy and therapeutics 20080601

Title: Cefepime and its role in pediatric infections.

Journal: Recent patents on anti-infective drug discovery 20080601

Title: First isolation of a VIM-producing Klebsiella pneumoniae from a seven-year-old child in Venezuela.

Journal: Journal of infection in developing countries 20080601

Title: Efficacy and safety evaluation of fixed dose combination of cefepime and amikacin in comparison with cefepime alone in treatment of nosocomial pneumonia patients.

Journal: Current clinical pharmacology 20080501

Title: High-level cefepime resistance in Escherichia coli from Singapore producing OXA-1 beta-lactamase.

Journal: International journal of antimicrobial agents 20080401

Title: Evaluation of area under the inhibitory curve (AUIC) and time above the minimum inhibitory concentration (T>MIC) as predictors of outcome for cefepime and ceftazidime in serious bacterial infections.

Journal: International journal of antimicrobial agents 20080401

Title: Gram-negative organisms predominate in Hickman line-related infections in non-neutropenic patients with hematological malignancies.

Journal: The Journal of infection 20080401

Title: Cefepime in intensive care unit patients: validation of a population pharmacokinetic approach and influence of covariables.

Journal: International journal of clinical pharmacology and therapeutics 20080401

Title: Bacterial and fungal pneumonias after lung transplantation.

Journal: Transplantation proceedings 20080401

Title: [Preparing antibiotics for infusion: not as simple as it appears!].

Journal: Kinderkrankenschwester : Organ der Sektion Kinderkrankenpflege 20080401

Title: Cefepime for prophylaxis of infections in the surgery of cholelithiasis. Results of a multicentric comparative trial.

Journal: Acta bio-medica : Atenei Parmensis 20080401

Title: Peritoneal pharmacokinetics of cefepime in laparotomy patients with inflammatory bowel disease, and dosage considerations for surgical intra-abdominal infections based on pharmacodynamic assessment.

Journal: Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 20080401

Title: Development of breakpoints of cephems for intraabdominal infections based on pharmacokinetics and pharmacodynamics in the peritoneal fluid of patients.

Journal: Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 20080401

Title: Simultaneous determination of five beta-lactam antibiotics (cefepim, ceftazidim, cefuroxim, meropenem and piperacillin) in human plasma by high-performance liquid chromatography with ultraviolet detection.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20080315

Title: The neurotoxicity and safety of treatment with cefepime in patients with renal failure.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20080301

Title: In vitro activity of cefepime, imipenem, tigecycline, and gentamicin, alone and in combination, against extended-spectrum beta-lactamase-producing Klebsiella pneumoniae and Escherichia coli.

Journal: Pharmacotherapy 20080301

Title: [Clinical case of the month. Antibiotics and hemodialysis: three cases of neurotoxicity from Maxipime].

Journal: Revue medicale de Liege 20080301

Title: Influence of E. coli lipopolysaccharide induced fever on the plasma kinetics of cefepime in cross-bred calves.

Journal: Veterinary research communications 20080201

Title: Pacemaker pocket infection due to Mycobacterium goodii: case report and review of the literature.

Journal: Connecticut medicine 20080201

Title: Research and clinical value of antibacterial-application software.

Journal: Chinese medical journal 20080105

Title: Efficacy and safety of cefepime in late-onset ventilator-associated pneumonia in infants: a pilot randomized and controlled study.

Journal: Annals of tropical medicine and parasitology 20080101

Title: Panipenem versus cefepime as empirical monotherapy in adult cancer patients with febrile neutropenia: a prospective randomized trial.

Journal: Japanese journal of clinical oncology 20080101

Title: Evaluation of a modified double-disc synergy test for detection of extended spectrum beta-lactamases in AMPC beta-lactamase-producing proteus mirabilis.

Journal: Indian journal of medical microbiology 20080101

Title: Occurrence of ESBL & Amp-C beta-lactamases & susceptibility to newer antimicrobial agents in complicated UTI.

Journal: The Indian journal of medical research 20080101

Title: Renal failure is a risk factor for cefepime-induced encephalopathy.

Journal: Journal of nephrology 20080101

Title: [Emergence of extended-spectrum beta-lactamases in Pseudomonas aeruginosa: about 24 cases at Rouen University Hospital].

Journal: Pathologie-biologie 20080101

Title: [The impact of different renal function measuring methods on the dosages of meropenem, piperacillin/tazobactam and cefepime in critically ill patients].

Journal: Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria 20080101

Title: Simultaneous determination of cefepime, vancomycin and imipenem in human plasma of burn patients by high-performance liquid chromatography.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20071215

Title: Antibiotic use in nursing home-acquired pneumonia.

Journal: Journal of the American Geriatrics Society 20071101

Title: [Pseudoperiodic EEG heralding a cefepime-induced encephalopathy].

Journal: Revue neurologique 20071101

Title: Pharmacokinetic disposition and bioavailability of cefepime in buffalo calves.

Journal: Journal of veterinary pharmacology and therapeutics 20071001

Title: Pharmacokinetics of ceftazidime and cefepime in burn patients: the importance of age and creatinine clearance.

Journal: International journal of clinical pharmacology and therapeutics 20071001

Title: Impact of antibiotic restriction on broad spectrum antibiotic usage in the ICU of a developing country.

Journal: JPMA. The Journal of the Pakistan Medical Association 20071001

Title: Pharmacokinetic and pharmacodynamic profiling of cefepime in plasma and peritoneal fluid of abdominal surgery patients.

Journal: International journal of antimicrobial agents 20070901

Title: Comparison of the probability of target attainment between ceftriaxone and cefepime in the cerebrospinal fluid and serum against Streptococcus pneumoniae.

Journal: Diagnostic microbiology and infectious disease 20070801

Title: Blood-brain barrier penetration of cefepime after neurosurgery.

Journal: Chinese medical journal 20070705

Title: A randomized comparison of empiric or pre-emptive antibiotic therapy after hematopoietic stem cell transplantation.

Journal: Bone marrow transplantation 20070701

Title: Cefepime plus amikacin as an initial empirical therapy of febrile neutropenia in paediatric cancer patients.

Journal: Singapore medical journal 20070701

Title: Could geriatric comprehensive assessment predict the outcome of pneumonia in the very old?

Journal: Age and ageing 20070701

Title: Simultaneous determination of cefepime and vancomycin in plasma and cerebrospinal fluid by MEKC with direct sample injection and application for bacterial meningitis.

Journal: Electrophoresis 20070601

Title: Use of cefepime for the treatment of infections caused by extended spectrum: beta-lactamase-producing Klebsiella pneumoniae and Escherichia coli.

Journal: Singapore medical journal 20070601

Title: A randomized prospective study of cefepime plus metronidazole with imipenem-cilastatin in the treatment of intra-abdominal infections.

Journal: Infection 20070601

Title: Cefepime-induced encephalopathy with triphasic waves in three Asian patients.

Journal: Annals of the Academy of Medicine, Singapore 20070601

Title: [Emergence of beta-lactam-dependent Bacillus cereus associated with prolonged treatment with cefepime in a neutropenic patient].

Journal: The Korean journal of laboratory medicine 20070601

Title: Cefepime pharmacodynamics in patients with extended spectrum beta-lactamase (ESBL) and non-ESBL infections.

Journal: The Journal of infection 20070501

Title: Cefepime cerebrospinal fluid concentrations in neonatal bacterial meningitis.

Journal: The Annals of pharmacotherapy 20070501

Title: Efficacy and safety of cefepime: a systematic review and meta-analysis.

Journal: The Lancet. Infectious diseases 20070501

Title: Once-daily cefepime versus ceftriaxone for nursing home-acquired pneumonia.

Journal: Journal of the American Geriatrics Society 20070501

Title: [Cefepime and aztreonam shortages: we've run out of ammo].

Journal: Enfermedades infecciosas y microbiologia clinica 20070501

Title: Molecular epidemiology and characterization of resistance mechanisms to various antimicrobial agents in Acinetobacter baumannii isolated in Mérida, Venezuela.

Journal: Medical science monitor : international medical journal of experimental and clinical research 20070401

Title: Cefepime restriction improves gram-negative overall resistance patterns in neonatal intensive care unit.

Journal: The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases 20070401

Title: Bactericidal activity of cefepime and ceftriaxone tested against Streptococcus pneumoniae.

Journal: Diagnostic microbiology and infectious disease 20070301

Title: Comparative activities of cefepime and piperacillin/tazobactam tested against a global collection of Escherichia coli and Klebsiella spp. with an ESBL phenotype.

Journal: Diagnostic microbiology and infectious disease 20070301

Title: Piperacillin/tazobactam-induced seizure rapidly reversed by high flux hemodialysis in a patient on peritoneal dialysis.

Journal: The American journal of the medical sciences 20070301

Title: Comparative in vivo efficacy of meropenem, imipenem, and cefepime against Pseudomonas aeruginosa expressing MexA-MexB-OprM efflux pumps.

Journal: Diagnostic microbiology and infectious disease 20070201

Title: Cefepime versus ceftazidime: considerations for empirical use in critically ill patients.

Journal: International journal of antimicrobial agents 20070201

Title: Pasteurella multocida sepsis, due to a scratch from a pet cat, in a post-chemotherapy neutropenic patient with non-Hodgkin lymphoma.

Journal: International journal of hematology 20070201

Title: Breakthrough infection of Trichosporon asahii in a patient with chronic lymphocytic leukemia.

Journal: International journal of hematology 20070201

Title: Escherichia coli aortic valve endocarditis.

Journal: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20070201

Title: Comparisons of parenteral broad-spectrum cephalosporins tested against bacterial isolates from pediatric patients: report from the SENTRY Antimicrobial Surveillance Program (1998-2004).

Journal: Diagnostic microbiology and infectious disease 20070101

Title: Carbapenem-resistant Acinetobacter baumannii: an emerging threat for patients with post-neurosurgical meningitis.

Journal: International journal of antimicrobial agents 20070101

Title: Acute-phase response alters the disposition kinetics of cefepime following intravenous administration to rabbits.

Journal: Veterinary research communications 20070101

Title: High-risk febrile neutropenia in Auckland 2003-2004: the influence of the microbiology laboratory on patient treatment and the use of pathogen-specific therapy.

Journal: Internal medicine journal 20070101

Title: Inhibitory effects of ofloxacin and cefepime on enzyme activity of 6-phosphogluconate dehydrogenase from chicken liver.

Journal: Protein and peptide letters 20070101

Title: Selective immediate hypersensitivity to cefepime.

Journal: Journal of investigational allergology & clinical immunology 20070101

Title: Outpatient intravenous antibiotics for methicillin-resistant Staphylococcus aureus sinusitis.

Journal: American journal of rhinology 20070101

Title: [In vitro activity of ertapenem against staphylococci].

Journal: Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi 20070101

Title: [Efficacy of cefixime and cefepime vs. other cephalosporins in experimental plague of albino mice due to variants FI+ and FI- of the plague microbe].

Journal: Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20070101

Title: Cefepime monotherapy for treatment of febrile neutropenia in children.

Journal: Journal of paediatrics and child health 20061201

Title: Randomized study of cefepime versus ceftazidime plus amikacin in patients with solid tumors treated with high dose chemotherapy (HDC) and peripheral blood stem cell support (PBSCS) with febrile neutropenia.

Journal: Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 20061201

Title: Acute neurological deficits caused by cefipime: a case report and review of literature.

Journal: Acta neurologica Taiwanica 20061201

Title: Pharmacokinetic-pharmacodynamic rationale for cefepime dosing regimens in intensive care units.

Journal: The Journal of antimicrobial chemotherapy 20061101

Title: Pyogenic liver abscess: Klebsiella as an emerging pathogen.

Journal: Emergency radiology 20061101

Title: In vitro activity of cefepime combined with sulbactam against clinical isolates of carbapenem-resistant Acinetobacter spp.

Journal: International journal of antimicrobial agents 20061101

Title: Optimising antibiotic dosing regimens based on pharmacodynamic target attainment against Pseudomonas aeruginosa collected in Hungarian hospitals.

Journal: International journal of antimicrobial agents 20061101

Title: Antibiotic-resistance patterns and frequency of extended-spectrum beta-lactamase-producing isolates of Klebsiella pneumoniae in Tehran.

Journal: Medical science monitor : international medical journal of experimental and clinical research 20061101

Title: Use of cefepime for the treatment of infections caused by extended spectrum beta-lactamase-producing Klebsiella pneumoniae and Escherichia coli.

Journal: Diagnostic microbiology and infectious disease 20061101

Title: Phenotypic and genotypic detection of ESBL mediated cephalosporin resistance in Klebsiella pneumoniae: emergence of high resistance against cefepime, the fourth generation cephalosporin.

Journal: The Journal of infection 20061001

Title: Stability of cefepime and metronidazole prepared for simplified administration as a single product.

Journal: Diagnostic microbiology and infectious disease 20061001

Title: Evaluating broad-spectrum antimicrobials.

Journal: QJM : monthly journal of the Association of Physicians 20061001

Title: Treatment of bone and joint infections caused by Gram-negative bacilli with a cefepime-fluoroquinolone combination.

Journal: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20061001

Title: Ertapenem versus cefepime for initial empirical treatment of pneumonia acquired in skilled-care facilities or in hospitals outside the intensive care unit.

Journal: European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 20061001

Title: Emergence of cefotaxime resistance in Citrobacter freundii causing necrotizing fasciitis and osteomyelitis.

Journal: The Journal of infection 20060901

Title: Antimicrobial activity of cefepime tested against ceftazidime-resistant Gram-negative clinical strains from North American Hospitals: report from the SENTRY Antimicrobial Surveillance Program (1998-2004).

Journal: Diagnostic microbiology and infectious disease 20060901

Title: Errors committed by nursing technicians and assistants in administering antibiotics.

Journal: American journal of infection control 20060901

Title: A randomized, open-label, multicenter comparative study of the efficacy and safety of piperacillin-tazobactam and cefepime for the empirical treatment of febrile neutropenic episodes in patients with hematologic malignancies.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20060815

Title: Cefepime neurotoxicity: case report, pharmacokinetic considerations, and literature review.

Journal: Pharmacotherapy 20060801

Title: Efficacy of intravenous ciprofloxacin in patients with febrile neutropenia refractory to initial therapy.

Journal: Leukemia & lymphoma 20060801

Title: Cefepime- and cefixime-induced encephalopathy in a patient with normal renal function.

Journal: Neurology 20060725

Title: Treatment of cavitary pulmonary zygomycosis with surgical resection and posaconazole.

Journal: The Annals of thoracic surgery 20060701

Title: The effect of different doses of cisplatin on the pharmacokinetic parameters of cefepime in mice.

Journal: Laboratory animals 20060701

Title: Application of the ion pair concept to the n-octanol-water partitioning of cefepime and cefpirome.

Journal: International journal of pharmaceutics 20060619

Title: Influence of endotoxin induced fever on the pharmacokinetics of intramuscularly administered cefepime in rabbits.

Journal: Journal of veterinary science 20060601

Title: Prospective drug utilization evaluation of three broad-spectrum antimicrobials: cefepime, piperacillin-tazobactam and meropenem.

Journal: QJM : monthly journal of the Association of Physicians 20060601

Title: In vivo selection of Enterobacter aerogenes with reduced susceptibility to cefepime and carbapenems associated with decreased expression of a 40 kDa outer membrane protein and hyperproduction of AmpC beta-lactamase.

Journal: International journal of antimicrobial agents 20060601

Title: Clinical experiences of the infections caused by extended-spectrum beta-lactamase-producing Serratia marcescens at a medical center in Taiwan.

Journal: Japanese journal of infectious diseases 20060601

Title: Cefepime vs. Ampicillin/Sulbactam and Aztreonam as antibiotic prophylaxis in neurosurgical patients with external ventricular drain: result of a prospective randomized controlled clinical trial.

Journal: Journal of clinical pharmacy and therapeutics 20060601

Title: [Efficacies of ceftazidime and cefepime in rats with experimental pneumonia caused by extended-spectrum beta-lactamase-producing strain of Klebsiella pneumonia].

Journal: Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases 20060601

Title: Pilot study of continuous infusion cefepime in adult patients with cystic fibrosis.

Journal: The Journal of antimicrobial chemotherapy 20060501

Title: Extended-spectrum beta-lactamases and clinical outcomes: current data.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20060415

Title: Pharmacokinetics of cefepime in bile and gall bladder tissue after prophylactic administration in patients with extrahepatic biliary diseases.

Journal: International journal of antimicrobial agents 20060401

Title: Pharmacodynamic profiling of cefepime in plasma and cerebrospinal fluid of hospitalized patients with external ventriculostomies.

Journal: Diagnostic microbiology and infectious disease 20060301

Title: [Maxipime in the treatment of neonatal sepsis].

Journal: Georgian medical news 20060301

Title: Trimethoprim-sulfamethoxazole induced rash and fatal hematologic disorders.

Journal: The Journal of infection 20060201

Title: Nonconvulsive status epilepticus due to cefepime in a patient with normal renal function.

Journal: Epilepsy & behavior : E&B 20060201

Title: Empirical antibiotic monotherapy for febrile neutropenia: systematic review and meta-analysis of randomized controlled trials.

Journal: The Journal of antimicrobial chemotherapy 20060201

Title: Trough serum concentrations of beta-lactam antibiotics in cancer patients: inappropriateness of conventional schedules to pharmacokinetic/pharmacodynamic properties of beta-lactams.

Journal: International journal of antimicrobial agents 20060201

Title: [The combination effects of antibacterial agents against clinical isolated multiple-drug resistant Pseudomonas aeruginosa].

Journal: The Japanese journal of antibiotics 20060201

Title: High-dose cefepime as an alternative treatment for infections caused by TEM-24 ESBL-producing Enterobacter aerogenes in severely-ill patients.

Journal: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20060101

Title: Detection of a novel variant bla(CTX-M-3) extended spectrum beta-lactamase gene in a community-acquired Escherichia coli isolate.

Journal: Scandinavian journal of infectious diseases 20060101

Title: Monotherapy with piperacillin/tazobactam versus cefepime as empirical therapy for febrile neutropenia in pediatric cancer patients: a randomized comparison.

Journal: Pediatric hematology and oncology 20060101

Title: Experience with cefepime versus meropenem as empiric monotherapy for neutropenia and fever in pediatric patients with solid tumors.

Journal: Pediatric hematology and oncology 20060101

Title: Febrile neutropenia as the presenting sign of appendicitis in an adolescent with acute myelogenous leukemia.

Journal: Pediatric hematology and oncology 20060101

Title: [Cefepime as an empiric treatment of febrile neutropenia in patients after high dose therapy and autologous stem cell transplantation].

Journal: Casopis lekaru ceskych 20060101

Title: [Antimicrobial susceptibility of phenotypically extended spectrum beta-lactamase producing Pseudomonas aeruginosa and Acinetobacter baumannii isolates].

Journal: Mikrobiyoloji bulteni 20060101

Title: Modified double-disc test for detection of extended-spectrum beta-lactamases in Escherichia coli and Klebsiella pneumoniae.

Journal: British journal of biomedical science 20060101

Title: Development and in-house validation of a microbiological assay for determination of cefepime in injectable preparations.

Journal: Journal of AOAC International 20060101

Title: Nonsurgical treatment of bilateral emphysematous pyelonephritis in a diabetic patient.

Journal: Journal of nephrology 20060101

Title: [Resistance to cefepime in Enterobacter cloacae isolates from hospitals in Bogotá, Colombia].

Journal: Revista de salud publica (Bogota, Colombia) 20060101

Title: Staphylococcal scalded skin syndrome: a rare complication of a common pathogen.

Journal: The Journal of the Louisiana State Medical Society : official organ of the Louisiana State Medical Society 20060101

Title: Antimicrobial susceptibility of Staphylococcus aureus isolated from colonized hospital personnel.

Journal: Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi 20060101

Title: Susceptibility of Klebsiella spp. to cefpirome and cefepime.

Journal: Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi 20060101

Title: Cefepime- and cefixime-induced encephalopathy in a patient with normal renal function.

Journal: Neurology 20051213

Title: Pharmacokinetics of cefepime administered by i.v. and i.m. routes to ewes.

Journal: Journal of veterinary pharmacology and therapeutics 20051201

Title: Case of the month. Chronic recurrent multifocal osteomyelitis.

Journal: JAAPA : official journal of the American Academy of Physician Assistants 20051201

Title: Pseudomonas aeruginosa infective endocarditis presenting as bacterial meningitis.

Journal: The Journal of infection 20051101

Title: Simultaneous determination of cefepime and L-arginine by micellar electrokinetic chromatography and applications to commercial injections.

Journal: Journal of separation science 20051101

Title: Effect of cefepime on startle amplitude and prepulse inhibition of startle reflex in rats: manipulation of GABAA receptor function with midazolam.

Journal: Methods and findings in experimental and clinical pharmacology 20051101

Title: Determination of ceftazidime and cefepime in plasma and dialysate-ultrafiltrate from patients undergoing continuous veno-venous hemodiafiltration by HPLC.

Journal: Journal of pharmaceutical and biomedical analysis 20051004

Title: Pharmacodynamics of antimicrobials for the empirical treatment of nosocomial pneumonia: a report from the OPTAMA Program.

Journal: Critical care medicine 20051001

Title: Clinical implications of extended spectrum beta-lactamase (ESBL) producing Klebsiella species and Escherichia coli on cefepime effectiveness.

Journal: The Journal of infection 20051001

Title: Effects of hyperbaric oxygen treatment on liver functions, oxidative status and histology in septic rats.

Journal: Intensive care medicine 20050901

Title: Antimicrobial therapy for pulmonary pathogenic colonisation and infection by Pseudomonas aeruginosa in cystic fibrosis patients.

Journal: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20050901

Title: Cephalosporin-induced nonconvulsive status epilepticus: clinical and electroencephalographic features.

Journal: Epilepsia 20050901

Title: [Therapeutic effects of cefepime and sulbactam/cefoperazone on moderate and severe respiratory tract infection in children].

Journal: Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 20050901

Title: Pan-drug-resistant Pseudomonas aeruginosa causing nosocomial infection at a university hospital in Taiwan.

Journal: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20050801

Title: Pharmacodynamics of intermittent and continuous infusion piperacillin/tazobactam and cefepime against extended-spectrum beta-lactamase-producing organisms.

Journal: International journal of antimicrobial agents 20050801

Title: Cefepime in critically ill patients: continuous infusion vs. an intermittent dosing regimen.

Journal: International journal of clinical pharmacology and therapeutics 20050801

Title: Subcutaneous administration of cefepime.

Journal: Journal of pain and symptom management 20050801

Title: Comparative study of the disposition of levofloxacin, netilmicin and cefepime in the isolated rat lung.

Journal: The Journal of pharmacy and pharmacology 20050701

Title: Potency and spectrum trends for cefepime tested against 65746 clinical bacterial isolates collected in North American medical centers: results from the SENTRY Antimicrobial Surveillance Program (1998-2003).

Journal: Diagnostic microbiology and infectious disease 20050701

Title: [Comparison of different phenotypic methods detecting extended spectrum beta-lactamases in Pseudomonas aeruginosa and Acinetobacter baumannii strains].

Journal: Mikrobiyoloji bulteni 20050701

Title: Reevaluation of the cefepime minimal inhibitory concentrations and disk diffusion test zone diameter relationship for a worldwide collection of Enterobacteriaceae enriched for extended-spectrum beta-lactamase-producing organisms.

Journal: Diagnostic microbiology and infectious disease 20050601

Title: Continuous infusion beta-lactams for intensive care unit pulmonary infections.

Journal: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20050501

Title: Comprehensive in vitro evaluation of cefepime combined with aztreonam or ampicillin/sulbactam against multi-drug resistant Pseudomonas aeruginosa and Acinetobacter spp.

Journal: International journal of antimicrobial agents 20050501

Title: Cefepime and continuous renal replacement therapy (CRRT): in vitro permeability of two CRRT membranes and pharmacokinetics in four critically ill patients.

Journal: Clinical therapeutics 20050501

Title: Intermittent administration of betalactam-antibiotics for treatment of severe infection in hemodialysis patients.

Journal: European journal of medical research 20050420

Title: Occurrence of extended-spectrum beta-lactamases among chromosomal AmpC-producing Enterobacter cloacae, Citrobacter freundii, and Serratia marcescens in Korea and investigation of screening criteria.

Journal: Diagnostic microbiology and infectious disease 20050401

Title: [Rapid identification of the isomeric impurity in raw drug of cefepime dihydrochloride by liquid chromatography-tandem mass spectrometry].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20050401

Title: [Cefepime-induced encephalopathy: clinical and electroencephalographic features in seven patients].

Journal: Arquivos de neuro-psiquiatria 20050301

Title: Spontaneous adrenal hemorrhage during pregnancy: a review of the literature and a case report of successful conservative management.

Journal: Obstetrical & gynecological survey 20050301

Title: Comparative activity of oral and parenteral cephalosporins tested against multidrug-resistant Streptococcus pneumoniae: report from the SENTRY Antimicrobial Surveillance Program (1997-2003).

Journal: Diagnostic microbiology and infectious disease 20050201

Title: Activity of cefepime and carbapenems in experimental pneumonia caused by porin-deficient Klebsiella pneumoniae producing FOX-5 beta-lactamase.

Journal: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20050101

Title: Disposition kinetics, bioavailability and renal clearance of cefepime in calves.

Journal: Veterinary research communications 20050101

Title: Pharmacokinetics of intraperitoneal cefepime in automated peritoneal dialysis.

Journal: Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis 20050101

Title: [Images in medicine. Multiple brain abscess ].

Journal: Revista da Associacao Medica Brasileira (1992) 20050101

Title: [Efficacy and safety of cefepime in the treatment of bronchopulmonary disease exacerbation in pediatric patients with mucoviscidosis].

Journal: Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20050101

Title: [Role of cefepime in the treatment of hospital-acquired pneumonia].

Journal: Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20050101

Title: [In vitro activity of cefepime against ESBL-positive clinical strains of gram-negative rods].

Journal: Medycyna doswiadczalna i mikrobiologia 20050101

Title: Cefepime and the inoculum effect in tests with Klebsiella pneumoniae producing plasmid-mediated AmpC-type beta-lactamase.

Journal: The Journal of antimicrobial chemotherapy 20041201

Title: Stability of cefepime in icodextrin peritoneal dialysis solution.

Journal: The Annals of pharmacotherapy 20041201

Title: Treating serious infections: focus on cefepime.

Journal: Pharmacotherapy 20041201

Title: Left atrial myxoma prolapsing into the left ventricle. Case report and review of the literature.

Journal: Chemotherapy 20041201

Title: [Endocarditis due to the Neisseria elongata subspecies nitroreducens].

Journal: Enfermedades infecciosas y microbiologia clinica 20041101

Title: Relationship between pharmacokinetics and pharmacodynamics of beta-lactams and outcome.

Journal: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20041101

Title: In vitro activity of cefepime and cefpirome compared to other third-generation cephem antibiotics against gram-negative nosocomial pathogens.

Journal: Die Pharmazie 20041101

Title: Comparison of in vivo intrinsic activity of cefepime and imipenem in a Pseudomonas aeruginosa rabbit endocarditis model: effect of combination with tobramycin simulating human serum pharmacokinetics.

Journal: The Journal of antimicrobial chemotherapy 20041001

Title: An adult case of Chryseobacterium meningosepticum meningitis.

Journal: Japanese journal of infectious diseases 20041001

Title: Simultaneous determination of cefepime and grepafloxacin in human urine by high-performance liquid chromatography.

Journal: Journal of pharmaceutical and biomedical analysis 20040921

Title: Beta-lactam antibiotics: newer formulations and newer agents.

Journal: Infectious disease clinics of North America 20040901

Title: [Cefepime-associated encephalopathy in a patient with septic shock and renal failure].

Journal: Revista clinica espanola 20040901

Title: Antimicrobial susceptibility survey of Pseudomonas aeruginosa strains isolated from clinical sources.

Journal: Journal of the National Medical Association 20040801

Title: Randomized trial of cefepime monotherapy or cefepime in combination with amikacin as empirical therapy for febrile neutropenia.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20040715

Title: Monotherapy versus dual therapy based on risk categorization of febrile neutropenic patients.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20040715

Title: Fatal hemorrhagic pneumonia caused by infection due to Kytococcus sedentarius--a pathogen or passenger?

Journal: Annals of hematology 20040701

Title: Evaluation of a new cefepime-clavulanate ESBL Etest to detect extended-spectrum beta-lactamases in an Enterobacteriaceae strain collection.

Journal: The Journal of antimicrobial chemotherapy 20040701

Title: Comparison of 99mTc-DTPA and urea for measuring cefepime concentrations in epithelial lining fluid.

Journal: The European respiratory journal 20040701

Title: Case report: Pseudomonas aeruginosa-related intervertebral discitis in a young boy with medulloblastoma.

Journal: Journal of neuro-oncology 20040701

Title: Determination of cefepime in plasma and cerebrospinal fluid by micellar electrokinetic chromatography with direct sample injection.

Journal: Electrophoresis 20040601

Title: In vitro activities of beta-lactam antibiotics alone and in combination with sulbactam against Gram-negative bacteria.

Journal: International journal of antimicrobial agents 20040601

Title: Retrospective study of clinical outcomes with extended-spectrum beta-lactamases--a different interpretation.

Journal: Pharmacotherapy 20040601

Title: In vitro activities of antibiotic combinations against clincal isolates of Pseudomonas aeruginosa.

Journal: The Kaohsiung journal of medical sciences 20040601

Title: Resistance to imipenem, cefepime, and cefpirome associated with mutation in Omp36 osmoporin of Enterobacter aerogenes.

Journal: Biochemical and biophysical research communications 20040507

Title: Exploring the effectiveness of tazobactam against ceftazidime resistant Escherichia coli: insights from the comparison between susceptibility testing and beta-lactamase inhibition.

Journal: FEMS microbiology letters 20040501

Title: Comparison of the double-disk, combined disk, and Etest methods for detecting metallo-beta-lactamases in gram-negative bacilli.

Journal: Diagnostic microbiology and infectious disease 20040501

Title: In vitro killing of parenteral beta-lactams against standard and high inocula of extended-spectrum beta-lactamase and non-ESBL producing Klebsiella pneumoniae.

Journal: Diagnostic microbiology and infectious disease 20040501

Title: Intrapulmonary concentrations of cefepime.

Journal: Critical care medicine 20040501

Title: Reversible coma secondary to cefepime neurotoxicity.

Journal: The Annals of pharmacotherapy 20040401

Title: Cefepime-induced non-convulsive status epilepticus in a peritoneal dialysis patient.

Journal: Pediatric nephrology (Berlin, Germany) 20040401

Title: Cefepime vs. Meropenem as empirical therapy for neutropenic fever in children with lymphoma and solid tumours.

Journal: Pediatric blood & cancer 20040301

Title: A case of IgE-mediated hypersensitivity to cefepime.

Journal: Allergy 20040201

Title: Cefepime-induced encephalopathy.

Journal: International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases 20040101

Title: Nonconvulsive status epilepticus associated with cefepime in a patient undergoing autologous stem cell transplantation.

Journal: Bone marrow transplantation 20040101

Title: Cefepime versus ceftazidime for treatment of pneumonia.

Journal: The Journal of international medical research 20040101

Title: [3-Year experience of use of cefepime (Maxipime) for the treatment of hospital infections in a specialized surgical hospital].

Journal: Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20040101

Title: A prospective, randomized study comparing cefepime and imipenem-cilastatin in the empirical treatment of febrile neutropenia in patients treated for haematological malignancies.

Journal: Scandinavian journal of infectious diseases 20040101

Title: [Risk factors of pseudomonas infection in hemoblastosis patients].

Journal: Zhurnal mikrobiologii, epidemiologii, i immunobiologii 20040101

Title: The cost-effectiveness of cefepime plus metronidazole versus imipenem/cilastatin in the treatment of complicated intra-abdominal infection.

Journal: Surgical infections 20040101

Title: [Respiratory fluoroquinolones in the treatment of exacerbations of chronic obstructive lung disease].

Journal: Problemy tuberkuleza i boleznei legkikh 20040101

Title: [Imipenem and cefepime in empirical therapy of infectious complications after radical surgeries in patients with invasive cancer of the urinary bladder].

Journal: Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20040101

Title: [Study of cefepime in Russia].

Journal: Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20040101

Title: In vitro activity of combination therapy with cefepime, piperacillin-tazobactam, or meropenem with ciprofloxacin against multidrug-resistant Pseudomonas aeruginosa strains.

Journal: Chemotherapy 20031201

Title: In vitro effects of some antibiotics on glutathione reductase from sheep liver.

Journal: Journal of enzyme inhibition and medicinal chemistry 20031201

Title: A simple and sensitive GC method for determination of N-methylpyrrolidine in cefepime and its preparation.

Journal: Journal of pharmaceutical and biomedical analysis 20031124

Title: Neutropenia in patients receiving long-term cefepime therapy for osteomyelitis.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20031101

Title: Cefepime versus cefpirome: the importance of creatinine clearance.

Journal: Anesthesia and analgesia 20031001

Title: Treatment of febrile neutropenic patients with cancer who require hospitalization: a prospective randomized study comparing imipenem and cefepime.

Journal: Cancer 20030901

Title: Adsorptive stripping voltammetric determination of cefepime at the mercury electrode in human urine and cerebrospinal fluid, and differential pulse polarographic determination in serum.

Journal: Journal of pharmaceutical sciences 20030901

Title: Antimicrobial spectrum of activity for meropenem and nine broad spectrum antimicrobials: report from the MYSTIC Program (2002) in North America.

Journal: Diagnostic microbiology and infectious disease 20030901

Title: Post-exposure effects of cefepime and cefpirome on isogenic Escherichia coli hosts producing SHV-extended-spectrum beta-lactamases.

Journal: Journal of chemotherapy (Florence, Italy) 20030801

Title: Steady-state plasma and intrapulmonary concentrations of cefepime administered in continuous infusion in critically ill patients with severe nosocomial pneumonia.

Journal: Critical care medicine 20030801

Title: Antibiotic tissue concentrations revisited in lungs.

Journal: Critical care medicine 20030801

Title: [Yearly changes in antibacterial activities of cefozopran against various clinical isolates between 1996 and 2001--I. Gram-positive bacteria].

Journal: The Japanese journal of antibiotics 20030801

Title: [Yearly changes in antibacterial activities of cefozopran against various clinical isolates between 1996 and 2001--II. Gram-negative bacteria].

Journal: The Japanese journal of antibiotics 20030801

Title: Serum bactericidal activity of trovafloxacin, in combination with cefepime or amikacin, in healthy volunteers.

Journal: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20030701

Title: Stability of cefepime hydrochloride in AutoDose Infusion System bags.

Journal: The Annals of pharmacotherapy 20030601

Title: Cefepime versus ticarcillin and clavulanate potassium and aztreonam for febrile neutropenia therapy in high-dose chemotherapy patients.

Journal: American journal of clinical oncology 20030601

Title: In vitro activity of gatifloxacin alone and in combination with cefepime, meropenem, piperacillin and gentamicin against multidrug-resistant organisms.

Journal: The Journal of antimicrobial chemotherapy 20030501

Title: Experimental prediction of the evolution of cefepime resistance from the CMY-2 AmpC beta-lactamase.

Journal: Genetics 20030501

Title: Neurotoxicity induced by Cefepime in a very old hemodialysis patient.

Journal: Clinical nephrology 20030501

Title: Role of pharmacodynamics in designing dosage regimens for beta-lactams.

Journal: Connecticut medicine 20030501

Title: Is there a rationale for the continuous infusion of cefepime? A multidisciplinary approach.

Journal: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20030501

Title: Determination of the dissociation constants of the cephalosporins cefepime and cefpirome using UV spectrometry and pH potentiometry.

Journal: Journal of pharmaceutical and biomedical analysis 20030410

Title: Enterobacter cloacae ventriculitis successfully treated with cefepime and gentamicin: case report and review of the literature.

Journal: Pharmacotherapy 20030401

Title: Experimental prediction of the natural evolution of antibiotic resistance.

Journal: Genetics 20030401

Title: Antibiotic prophylaxis in elective thoracic surgery: cefuroxime versus cefepime.

Journal: The Thoracic and cardiovascular surgeon 20030401

Title: [Evaluation of a E-test method to detect bactericidy of beta lactam-aminoglycoside associations against Pseudomonas aeruginosa isolates from cystic fibrosis].

Journal: Pathologie-biologie 20030401

Title: Diffusion of cefepime into cancellous and cortical bone tissue.

Journal: Journal of chemotherapy (Florence, Italy) 20030401

Title: [Cefepime-amikacin combination in febrile neutropenic children with malignant hemopathy or tumor].

Journal: Archives de pediatrie : organe officiel de la Societe francaise de pediatrie 20030401

Title: [Meningitis caused by multiresistant E. coli after an echo-directed transrectal biopsy].

Journal: Actas urologicas espanolas 20030401

Title: Cefepime tissue penetration in experimental acute pancreatitis.

Journal: Pancreas 20030301

Title: Stability and compatibility study of cefepime in comparison with ceftazidime for potential administration by continuous infusion under conditions pertinent to ambulatory treatment of cystic fibrosis patients and to administration in intensive care units.

Journal: The Journal of antimicrobial chemotherapy 20030301

Title: Integration of population pharmacokinetics, a pharmacodynamic target, and microbiologic surveillance data to generate a rational empiric dosing strategy for cefepime against Pseudomonas aeruginosa.

Journal: Pharmacotherapy 20030301

Title: Disposition of cefepime in the central nervous system of patients with external ventricular drains.

Journal: Pharmacotherapy 20030301

Title: Retrospective review of neurotoxicity induced by cefepime and ceftazidime.

Journal: Pharmacotherapy 20030301

Title: Cefepime use in a pediatric intensive care unit reduces colonization with resistant bacilli.

Journal: The Pediatric infectious disease journal 20030201

Title: Pancreatic concentrations of cefepime in experimental necrotizing pancreatitis.

Journal: Journal of chemotherapy (Florence, Italy) 20030201

Title: A comparison of antibiotic regimens in the treatment of acute melioidosis in a mouse model.

Journal: The Journal of antimicrobial chemotherapy 20030101

Title: Sustained activity and spectrum of selected extended-spectrum beta-lactams (carbapenems and cefepime) against Enterobacter spp. and ESBL-producing Klebsiella spp.: report from the SENTRY antimicrobial surveillance program (USA, 1997-2000).

Journal: International journal of antimicrobial agents 20030101

Title: Determination of the frequency of inadequate antibiotic therapy using calculation of indication failure (IF), cumulative indication failure (CIF), and balanced indication failure (BIF).

Journal: Wiener medizinische Wochenschrift (1946) 20030101

Title: [Comparative clinical and epidemiological evaluation of beta-lactam antibiotics in the treatment of intraabdominal infections].

Journal: Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20030101

Title: Lack of efflux mechanism in a clinical isolate of Pseudomonas aeruginosa highly resistant to beta-lactams and imipenem.

Journal: Folia microbiologica 20030101

Title: [Cefepime: the new option of target antibiotic therapy].

Journal: Przeglad lekarski 20030101

Title: [The present and the future of cefepime, a 4th generation cephalosporin].

Journal: Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20030101

Title: [Comparative in vitro activity of cefepime and other antibiotics against clinical strains of gram-negative bacteria].

Journal: Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20030101

Title: [Experience with maxipime in neurosurgical clinic].

Journal: Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20030101

Title: [Cefepime treatment efficacy in surgical patients].

Journal: Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20030101

Title: [Cefepime (maxipime) in the treatment of severe urinary tract infection].

Journal: Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20030101

Title: [Cefepime/amikacin in the empirical antibacterial therapy for patients with hemoblastosis of different forms].

Journal: Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20030101

Title: [Empirical cefepime monotherapy in febrile neutropenia].

Journal: Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20030101

Title: [Cefepime in the treatment of hospital-acquired pneumonia].

Journal: Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20030101

Title: Intraperitoneal infusion allows therapeutic plasma levels of cefepime.

Journal: Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis 20030101

Title: Cefepime: a review of its use in the management of hospitalized patients with pneumonia.

Journal: American journal of respiratory medicine : drugs, devices, and other interventions 20030101

Title: [Activity of fourth generation cephalosporins against clinical isolates of Enterobacteriaceae].

Journal: Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi 20030101

Title: Cefepime or carbapenem treatment for febrile neutropenia as a single agent is as effective as a combination of 4th-generation cephalosporin + aminoglycosides: comparative study.

Journal: American journal of hematology 20021201

Title: Continuous infusion versus intermittent administration of cefepime in patients with Gram-negative bacilli bacteraemia.

Journal: The Journal of pharmacy and pharmacology 20021201

Title: Clinical and bacteriological results from the administration of Cefepime (Maxipime) in patients with severe sepsis.

Journal: Medical science monitor : international medical journal of experimental and clinical research 20021101

Title: Antimicrobial susceptibility of major pathogens of orofacial odontogenic infections to 11 beta-lactam antibiotics.

Journal: Oral microbiology and immunology 20021001

Title: A multicenter comparative study of cefepime versus broad-spectrum antibacterial therapy in moderate and severe bacterial infections.

Journal: The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases 20021001

Title: Pharmacodynamics of cefepime in patients with Gram-negative infections.

Journal: The Journal of antimicrobial chemotherapy 20020901

Title: The efficacy of prophylactic outpatient antibiotics for the prevention of neutropenic fever associated with high-dose etoposide (VP-16) for stem cell mobilization.

Journal: Bone marrow transplantation 20020901

Title: Cefepime, piperacillin/tazobactam, gentamicin, ciprofloxacin, and levofloxacin alone and in combination against Pseudomonas aeruginosa.

Journal: Diagnostic microbiology and infectious disease 20020901

Title: Safety and efficacy of cefepime versus ceftazidime in the treatment of severe infections.

Journal: Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi 20020901

Title: Surgical antibiotic prophylaxis in a Turkish university hospital.

Journal: Journal of chemotherapy (Florence, Italy) 20020801

Title: Cefepime plus amikacin versus piperacillin-tazobactam plus amikacin for initial antibiotic therapy in haematology patients with febrile neutropenia: results of an open, randomized, multicentre trial.

Journal: The Journal of antimicrobial chemotherapy 20020701

Title: Geographic variations in activity of broad-spectrum beta-lactams against Pseudomonas aeruginosa: summary of the worldwide SENTRY Antimicrobial Surveillance Program (1997-2000).

Journal: Diagnostic microbiology and infectious disease 20020701

Title: Emerging antimicrobial resistances among Proteus mirabilis in Europe: report from the MYSTIC Program (1997-2001). Meropenem Yearly Susceptibility Test Information Collection.

Journal: Journal of chemotherapy (Florence, Italy) 20020601

Title: Alteration of pore properties of Escherichia coli OmpF induced by mutation of key residues in anti-loop 3 region.

Journal: The Biochemical journal 20020501

Title: Cefepime MIC as a predictor of the extended-spectrum beta-lactamase type in Klebsiella pneumoniae, Taiwan.

Journal: Emerging infectious diseases 20020501

Title: Extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella species: risk factors for colonization and impact of antimicrobial formulary interventions on colonization prevalence.

Journal: Infection control and hospital epidemiology 20020501

Title: Penetration of meropenem and cefepim into pancreatic tissue during the course of experimental acute pancreatitis.

Journal: Pancreas 20020401

Title: Klebsiella pneumoniae brain abscess in a Taiwanese adult.

Journal: The Journal of infection 20020401

Title: Pharmacodynamic considerations in the treatment of moderate to severe pseudomonal infections with cefepime.

Journal: The Journal of antimicrobial chemotherapy 20020301

Title: Cefepime versus ceftazidime as empiric monotherapy for fever and neutropenia in children with cancer.

Journal: The Pediatric infectious disease journal 20020301

Title: Cefepime is efficacious against penicillin- and quinolone-resistant pneumococci in experimental meningitis.

Journal: The Journal of antimicrobial chemotherapy 20020201

Title: Nonconvulsive status epilepticus in dialysis patients.

Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 20020201

Title: Cefepime-induced neurotoxicity: an underestimated complication of antibiotherapy in patients with acute renal failure.

Journal: Intensive care medicine 20020201

Title: A randomized monocentric trial in febrile neutropenic patients: ceftriaxone and gentamicin vs cefepime and gentamicin.

Journal: Annals of hematology 20020101

Title: Clinical evaluation of the Vitek automated system with cards GNS 122 and 127 and VTK-R07.01 software for antimicrobial susceptibility testing of Pseudomonas aeruginosa.

Journal: Diagnostic microbiology and infectious disease 20020101

Title: Intravitreal penetration of cefepime after systemic administration to humans.

Journal: Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde 20020101

Title: Stability of cefepime dihydrochloride monohydrate in solid state.

Journal: Acta poloniae pharmaceutica 20020101

Title: Cefepime monotherapy as an empirical initial treatment of patients with febrile neutropenia.

Journal: Medical oncology (Northwood, London, England) 20020101

Title: [Cefepime (Maxipime) treatment efficacy in surgical patients ].

Journal: Chirurgia (Bucharest, Romania : 1990) 20020101

Title: Severe neurotoxicity of cefepime in uremic patients.

Journal: Annals of internal medicine 20011204

Title: [Activity of new fluoroquinolones against clinical isolates of Acinetobacter baumannii].

Journal: Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia 20011201

Title: The effectiveness of systemic antibiotics in preventing postoperative, intraabdominal adhesions in an animal model.

Journal: The Journal of surgical research 20011101

Title: Susceptibility of pseudomonas aeruginosa to cefepime versus ceftazidime in patients with cystic fibrosis.

Journal: Pharmacotherapy 20011101

Title: Effect of inoculum size on the antibacterial activity of cefpirome and cefepime against Klebsiella pneumoniae strains producing SHV extended-spectrum beta-lactamases.

Journal: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20011101

Title: Invasive pulmonary aspergillosis in a puerperant with drug-induced agranulocytosis.

Journal: Internal medicine (Tokyo, Japan) 20011101

Title: Cefepime versus cefotaxime for empirical treatment of bacterial pneumonia in HIV-infected patients: an open, randomized trial.

Journal: The Journal of antimicrobial chemotherapy 20011001

Title: Application of the IDSA guidelines for the use of antimicrobial agents in neutropenic patients: impact on reducing the use of glycopeptides.

Journal: Infection control and hospital epidemiology 20011001

Title: [Antimicrobial activities of carbapenems and fourth generation cephems against clinically isolated strains].

Journal: The Japanese journal of antibiotics 20010901

Title: Cefepime in vitro activity against derepressed extended-spectrum beta-lactamase (ESBL)-producing and non-ESBL-producing Enterobacter cloacae by a disc diffusion method.

Journal: The Journal of antimicrobial chemotherapy 20010801

Title: Nonconvulsive status epilepticus associated with cephalosporins in patients with renal failure.

Journal: The American journal of medicine 20010801

Title: Comparative in vitro antimicrobial activity of a new carbapenem, E1010, and tentative disc diffusion test interpretative criteria.

Journal: The Journal of antimicrobial chemotherapy 20010701

Title: Cefepime versus vancomycin plus netilmicin therapy for continuous ambulatory peritoneal dialysis-associated peritonitis.

Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 20010701

Title: Effect of cyclosporine, a P-glycoprotein inhibitor, on the pharmacokinetics of cefepime in rat blood and brain: a microdialysis study.

Journal: Life sciences 20010601

Title: Comparison of cefepime pharmacokinetics in neonatal foals and adult dogs.

Journal: Journal of veterinary pharmacology and therapeutics 20010601

Title: Cost-effectiveness of cefepime + netilmicin or ceftazidime + amikacin or meropenem monotherapy in febrile neutropenic children with malignancy in Turkey.

Journal: Journal of chemotherapy (Florence, Italy) 20010601

Title: Efficacy of cefepime versus ceftazidime in the treatment of adult pneumonia.

Journal: Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi 20010601

Title: Abiotrophia bacteremia in a patient with neutropenic fever and antimicrobial susceptibility testing of Abiotrophia isolates.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20010515

Title: Efficacy of gatifloxacin alone and in combination with cefepime against penicillin-resistant Streptococcus pneumoniae in a rabbit meningitis model and in vitro.

Journal: The Journal of antimicrobial chemotherapy 20010501

Title: Pancreatic concentrations of cefepime.

Journal: The Journal of antimicrobial chemotherapy 20010501

Title: Efficiency of cefepime in postoperative meningitis attributable to Enterobacter aerogenes.

Journal: The Journal of trauma 20010501

Title: High-performance liquid chromatographic determination of cefepime in human plasma and in urine and dialysis fluid using a column-switching technique.

Journal: Journal of chromatography. B, Biomedical sciences and applications 20010425

Title: Determination and pharmacokinetic study of unbound cefepime in rat bile by liquid chromatography with on-line microdialysis.

Journal: Journal of chromatography. A 20010420

Title: Randomized comparison of cefepime versus ceftazidime monotherapy for fever and neutropenia in children with solid tumors.

Journal: Medical and pediatric oncology 20010401

Title: Prediction of gram-negative bacteremia in patients with cancer and febrile neutropenia by means of interleukin-8 levels in serum: targeting empirical monotherapy versus combination therapy.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20010301

Title: Cefepime microbiologic profile and update.

Journal: The Pediatric infectious disease journal 20010301

Title: Review of the pharmacokinetics of cefepime in children.

Journal: The Pediatric infectious disease journal 20010301

Title: Empiric use of cefepime in the treatment of lower respiratory tract infections in children.

Journal: The Pediatric infectious disease journal 20010301

Title: Empiric use of cefepime in the treatment of serious urinary tract infections in children.

Journal: The Pediatric infectious disease journal 20010301

Title: Cefepime in the empiric treatment of meningitis in children.

Journal: The Pediatric infectious disease journal 20010301

Title: Comparative study of cefepime versus ceftazidime in the empiric treatment of pediatric cancer patients with fever and neutropenia.

Journal: The Pediatric infectious disease journal 20010301

Title: Extension of resistance to cefepime and cefpirome associated to a six amino acid deletion in the H-10 helix of the cephalosporinase of an Enterobacter cloacae clinical isolate.

Journal: FEMS microbiology letters 20010220

Title: Multicentre study of the in vitro activity of cefepime, a broad-spectrum cephalosporin, compared to other broad-spectrum agents.

Journal: Pathology 20010201

Title: [Activity of cefepime compared with other antibiotics against major hospital bacterial pathogens].

Journal: Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20010201

Title: [Combination effect of arbekacin and cefepime on mixed culture of MRSA and P. aeruginosa].

Journal: The Japanese journal of antibiotics 20010201

Title: Neuropsychiatric symptoms during cefepime treatment.

Journal: Pharmacy world & science : PWS 20010201

Title: Successful use of recombinant tissue plasminogen activator in a patient with relapsing peritonitis.

Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 20010101

Title: In vitro synergy between cefepime and vancomycin against methicillin-susceptible and -resistant Staphylococcus aureus and Staphylococcus epidermidis.

Journal: The Journal of antimicrobial chemotherapy 20010101

Title: Ocular penetration of cefepime following systemic administration in humans.

Journal: Ophthalmic surgery and lasers 20010101

Title: Comparative activities of isepamicin, amikacin, cefepime, and ciprofloxacin alone or in combination with other antibiotics against Stenotrophomonas maltophilia.

Journal: European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 20010101

Title: Pharmacokinetic population study to describe cefepime lung concentrations.

Journal: Pulmonary pharmacology & therapeutics 20010101

Title: Treatment of febrile neutropenia with cefepime monotherapy.

Journal: Chemotherapy 20010101

Title: The effects of cefephim, G-CSF, and sucralfate on bacterial translocation in experimentally induced acute pancreatitis.

Journal: Surgery today 20010101

Title: Activity of cefepime, cefotaxime, ceftazidime, and aztreonam against extended-spectrum-producing isolates of Klebsiella pneumoniae and Escherichia coli from Chilean hospitals.

Journal: Diagnostic microbiology and infectious disease 20010101

Title: [Cefepime (maxipime) in the treatment of abdominal surgical infections].

Journal: Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20010101

Title: Effects of cefepime and meropenem on the gastrointestinal colonization of surgical patients by Candida albicans.

Journal: Chemotherapy 20010101

Title: Comparison of cefepime versus ceftriaxone-amikacin as empirical regimens for the treatment of febrile neutropenia in acute leukemia patients.

Journal: Chemotherapy 20010101

Title: Comparison of cefepime and ceftazidime in combination with amikacin in the empirical treatment of high-risk patients with febrile neutropenia: a prospective, randomized, multicenter study.

Journal: Scandinavian journal of infectious diseases 20010101

Title: [A fourth generation cephalosporin--cefepime (maxipime) in pediatrics].

Journal: Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20010101

Title: [Cefepime (maxipine) in treating abdominal surgical infections].

Journal: Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20010101

Title: [Use of maxipime in treating infections in neutropenic patients].

Journal: Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20010101

Title: [Experience in using the fourth generation cephalosporin cefepime (maxipime) in treating Russian patients with severe infections].

Journal: Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20010101

Title: Susceptibility of bacterial isolates to cefepime in comparison to other broad spectrum antimicrobial agents at a tertiary care center in Lebanon.

Journal: Le Journal medical libanais. The Lebanese medical journal 20010101

Title: [Cefepime (maxipime), large spectrum 4th generation cephalosporin, resistant to beta-lactamases].

Journal: Chirurgia (Bucharest, Romania : 1990) 20010101

Title: beta-lactam antibiotics as substrates for OCTN2, an organic cation/carnitine transporter.

Journal: The Journal of biological chemistry 20000121

Title: Synergistic antimycobacterial activity between ethambutol and the beta-lactam drug cefepime.

Journal: Diagnostic microbiology and infectious disease 19970701

Title: beta-Lactamase activity in mycobacteria including Mycobacterium avium and suppression of their growth by a beta-lactamase-stable antibiotic.

Journal: Microbios 19950101

Title: Efficacy of cefepime in a Staphylococcus aureus endocarditis rat model.

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Title: Neu, H.C., Safety of cefepime: a new extended-spectrum parenteral cephalosporin. Am J Med, 1996. 100(6A): p. 68S-75S.

Title: Wynd, M.A. and J.A. Paladino, Cefepime: a fourth-generation parenteral cephalosporin. Ann Pharmacother, 1996. 30(12): p. 1414-24.

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Tags:123171-59-5 Molecular Formula|123171-59-5 MDL|123171-59-5 SMILES|123171-59-5 Cefepime Dihydrochloride Monohydrate