Home Amines 1246086-78-1
1246086-78-1,MFCD22378484
Catalog No.:AA000MDO

1246086-78-1 | 2-Pyridinecarboxamide, N-[3-chloro-4-[[(2-chlorophenyl)amino]sulfonyl]phenyl]-

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1mg
≥98%
in stock  
$46.00   $32.00
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5mg
≥98%
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$156.00   $109.00
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10mg
≥98%
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$242.00   $169.00
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25mg
98% by HPLC
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$473.00   $331.00
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50mg
98% by HPLC
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$761.00   $533.00
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100mg
98% by HPLC
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$1,270.00   $889.00
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500mg
98% by HPLC
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$3,958.00   $2,771.00
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1000mg
98% by HPLC
in stock  
$6,295.00   $4,407.00
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  • Technical Information
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  • Technical Information
  • Properties
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Technical Information
Catalog Number:
AA000MDO
Chemical Name:
2-Pyridinecarboxamide, N-[3-chloro-4-[[(2-chlorophenyl)amino]sulfonyl]phenyl]-
CAS Number:
1246086-78-1
Molecular Formula:
C18H13Cl2N3O3S
Molecular Weight:
422.2851
MDL Number:
MFCD22378484
SMILES:
O=C(c1ccccn1)Nc1ccc(c(c1)Cl)S(=O)(=O)Nc1ccccc1Cl
Properties
Computed Properties
 
Complexity:
614  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
27  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
5  
XLogP3:
3.8  

Literature

Title: Tricyclic thiazolopyrazole derivatives as metabotropic glutamate receptor 4 positive allosteric modulators.

Journal: Journal of medicinal chemistry 20110728

Title: Synthesis and SAR of novel, 4-(phenylsulfamoyl)phenylacetamide mGlu4 positive allosteric modulators (PAMs) identified by functional high-throughput screening (HTS).

Journal: Bioorganic & medicinal chemistry letters 20100901

Title: Hong, Sang-Phyo; Liu, Kevin G.; Ma, Gil et al. Tricyclic Thiazolopyrazole Derivatives as Metabotropic Glutamate Receptor 4 Positive Allosteric Modulators. Journal of Medicinal Chemistry (2011), 54(14), 5070-5081.

Title: Engers, Darren W.; Gentry, Patrick R.; Williams, Richard et al. Synthesis and SAR of novel 4-(phenylsulfamoyl)phenylacetamide mGlu4 positive allosteric modulators (PAMs) identified by functional high-throughput screening (HTS). Bioorganic & Medicinal Chemistry Letters (2010), 20(17), 5175-5178.

Title: AJ Robichaud et al. Recent Progress on the Identification of Metabotropic Glutamate 4 Receptor Ligands and Their Potential Utility as CNS Therapeutics. ACS Chem. Neurosci. 2011, 2(8), 433-449.

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Tags:1246086-78-1 Molecular Formula|1246086-78-1 MDL|1246086-78-1 SMILES|1246086-78-1 2-Pyridinecarboxamide, N-[3-chloro-4-[[(2-chlorophenyl)amino]sulfonyl]phenyl]-