Name: Name:Pregna-1,4-diene-3,11,20-trione, 17,21-dihydroxy-16-methyl-, (16β)-
Brand: AABLOCKS
SKU: AA000MKC
Rating: 90 (10 reviews)

Technical Information

Catalog Number: AA000MKC

Chemical Name: Pregna-1,4-diene-3,11,20-trione, 17,21-dihydroxy-16-methyl-, (16β)-

CAS Number: 1247-42-3

Molecular Formula: C22H28O5

Molecular Weight: 372.4547

MDL Number: MFCD00083662

SMILES: OCC(=O)[C@@]1(O)[C@@H](C)C[C@@H]2[C@]1(C)CC(=O)[C@H]1[C@H]2CCC2=CC(=O)C=C[C@]12C

Properties

Complexity: 795

Covalently-Bonded Unit Count: 1

Defined Atom Stereocenter Count: 7

Defined Bond Stereocenter Count: 0

Formal Charge: 0

Heavy Atom Count: 27

Hydrogen Bond Acceptor Count: 5

Hydrogen Bond Donor Count: 2

Isotope Atom Count: 0

Rotatable Bond Count: 2

Undefined Atom Stereocenter Count: 0

Undefined Bond Stereocenter Count: 0

XLogP3: 1.9

Literature fold

Title: Comparative analysis the binding affinity of mycophenolic sodium and meprednisone with human serum albumin: Insight by NMR relaxation data and docking simulation.

Journal: Chemico-biological interactions20160325

Title: Theophylline, a methylxanthine drug induces osteopenia and alters calciotropic hormones, and prophylactic vitamin D treatment protects against these changes in rats.

Journal: Toxicology and applied pharmacology20160315

Title: [Pulmonary hemorrhage associated with celiac disease].

Journal: Archivos argentinos de pediatria20120801

Title: Severe neutropenia in a renal transplant patient suggesting an interaction between mycophenolate and fenofibrate.

Journal: Current drug safety20120201

Title: Corticosteroid administration for patients with coronary artery aneurysms after Kawasaki disease may be associated with impaired regression.

Journal: International journal of cardiology20120112

Title: Disruption of Transitional Stages in 24-h Blood Pressure Recording in Renal Transplant Recipients.

Journal: Frontiers in neurology20120101

Title: Autoimmune cholangitis associated to IgG4 related sclerosing disease.

Journal: Acta gastroenterologica Latinoamericana20110301

Title: Structure-based analysis of five novel disease-causing mutations in 21-hydroxylase-deficient patients.

Journal: PloS one20110101

Title: [Fulminating sclerosant peritonitis. Spectacular response to treatment with steroids].

Journal: Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia20100101

Title: Screening of 397 chemicals and development of a quantitative structure--activity relationship model for androgen receptor antagonism.

Journal: Chemical research in toxicology20080401

Title: Henoch-Schönlein Purpura in adults.

Journal: Clinics (Sao Paulo, Brazil)20080401

Title: [Drug-induced lichenoid eruptions].

Journal: Annales de dermatologie et de venereologie20060401

Title: Prevention and treatment of rejection after simultaneous pancreas-kidney transplantation.

Journal: Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih20050901

Title: 17alpha,21-Dihydroxy-16beta-methylpregna-1,4-diene-3,11,20-trione (meprednisone).

Journal: Acta crystallographica. Section C, Crystal structure communications20030401

Title: Scheuer, E. and E. Warshaw, Allergy to corticosteroids: update and review of epidemiology, clinical characteristics, and structural cross-reactivity. Am J Contact Dermat, 2003. 14(4): p. 179-87.

1247-42-3 | Pregna-1,4-diene-3,11,20-trione, 17,21-dihydroxy-16-methyl-, (16β)-