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Title: Endogenous acetaldehyde toxicity during antral follicular development in the mouse ovary.
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Title: Continuous de novo synthesis of neurosteroids is required for normal synaptic transmission and plasticity in the dentate gyrus of the rat hippocampus.
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Title: Expression of ghrelin and the ghrelin receptor in different stages of porcine corpus luteum development and the inhibitory effects of ghrelin on progesterone secretion, 3β-hydroxysteroid dehydrogenase (3β-honestly significant difference (HSD)) activity and protein expression.
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Title: Evidence that LPS-reactive arthritis in rats depends on the glial activity and the fractalkine-TNF-α signaling in the spinal cord.
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Title: Implication of allopregnanolone in the antinociceptive effect of N-palmitoylethanolamide in acute or persistent pain.
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Title: Treatment Options in Cushing's Disease.
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Title: Antioxidant-induced stress.
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Title: Combination drug delivery approaches in metastatic breast cancer.
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Title: Management Strategies for Aggressive Cushing's Syndrome: From Macroadenomas to Ectopics.
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Title: Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
Journal: PLoS computational biology 20111201
Title: Comparison of ketoconazole and estramustine for treating patients with castration-resistant prostate cancer.
Journal: Korean journal of urology 20111101
Title: Cushing's surgery: Role of the anesthesiologist.
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Title: Regulation of prolactin secretion during the estrus in rats: possible role of glucocorticoids.
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Title: Androgen suppression-induced stimulation of spermatogonial differentiation in juvenile spermatogonial depletion mice acts by elevating the testicular temperature.
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Title: Drug-induced protein free radical formation is attenuated by unsaturated fatty acids by scavenging drug-derived phenyl radical metabolites.
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Title: Lead optimization of 4-imidazolylflavans: new promising aromatase inhibitors.
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Title: A qualitative systematic review of the evidence base for non-cross-resistance between steroidal and non-steroidal aromatase inhibitors in metastatic breast cancer.
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Title: Synthesis of some novel androstanes as potential aromatase inhibitors.
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Title: Differences between the non-steroidal aromatase inhibitors anastrozole and letrozole--of clinical importance?
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Title: The potency and clinical efficacy of aromatase inhibitors across the breast cancer continuum.
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Title: Pharmacological evidence that Ca²+ channels and, to a lesser extent, K+ channels mediate the relaxation of testosterone in the canine basilar artery.
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Title: Hormone treatment of depression.
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Title: Identification and validation of novel human pregnane X receptor activators among prescribed drugs via ligand-based virtual screening.
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Title: Facile synthesis of chrysin-derivatives with promising activities as aromatase inhibitors.
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Title: Chemical modification of L-glutamine to alpha-amino glutarimide on autoclaving facilitates Agrobacterium infection of host and non-host plants: A new use of a known compound.
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Title: Aromatase inhibitors and antiepileptic drugs: a computational systems biology analysis.
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Title: Aromatase inhibitors in men: effects and therapeutic options.
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Title: Predicting selective drug targets in cancer through metabolic networks.
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Title: Melatonin reduces LH, 17 beta-estradiol and induces differential regulation of sex steroid receptors in reproductive tissues during rat ovulation.
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Title: Parallel screening of FDA-approved antineoplastic drugs for identifying sensitizers of TRAIL-induced apoptosis in cancer cells.
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Title: Exemestane in the adjuvant treatment of breast cancer in postmenopausal women.
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Title: Membrane-initiated estradiol signaling regulating sexual receptivity.
Journal: Frontiers in endocrinology 20110101
Title: The Neurosteroid Progesterone Underlies Estrogen Positive Feedback of the LH Surge.
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Title: Minimizing early relapse and maximizing treatment outcomes in hormone-sensitive postmenopausal breast cancer: efficacy review of AI trials.
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Title: A predictive ligand-based Bayesian model for human drug-induced liver injury.
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Title: In vivo alternative assessment of the chemicals that interfere with anterior pituitary POMC expression and interrenal steroidogenesis in POMC: EGFP transgenic zebrafish.
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Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.
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Title: Does administration of non-steroidal anti-inflammatory drug determine morphological changes in adrenal cortex: ultrastructural studies.
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Title: Steroidal and gonadal effects on neural cell proliferation in vitro in an adult songbird.
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Title: Short-term dynamic culture of rat testicular fragments as a model to assess effects on steroidogenesis--potential use and limitations.
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Title: Assessment of chemical effects on aromatase activity using the H295R cell line.
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Title: Investigating the mechanisms of aromatic amine-induced protein free radical formation by quantitative structure-activity relationships: implications for drug-induced agranulocytosis.
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Title: Pharmacophore modeling strategies for the development of novel nonsteroidal inhibitors of human aromatase (CYP19).
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Title: Water-soluble polymer-drug conjugates for combination chemotherapy against visceral leishmaniasis.
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Title: Achiral and chiral separations using MEKC, polyelectrolyte multilayer coatings, and mixed mode separation techniques with molecular micelles.
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Title: Evaluation of plasma and tissue estrogen suppression with third-generation aromatase inhibitors: of relevance to clinical understanding?
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Title: Treatment of Cushing disease: overview and recent findings.
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Title: FACE: the barefaced facts of AI potency.
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Title: Applicability of Generic Assays Based on Liquid Chromatography-Electrospray Mass Spectrometry to Study in vitro Metabolism of 55 Structurally Diverse Compounds.
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Title: Oocyte hydration in the Japanese eel (Anguilla japonica) during meiosis resumption and ovulation.
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Title: Human cytomegalovirus productively infects adrenocortical cells and induces an early cortisol response.
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Title: [Feminizing adrenal tumours in Spain: report of a case and review of the five previously published patients].
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Title: Regulation of inhibin/activin expression in rat early antral follicles.
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Title: Aromatase inhibitors for treatment of advanced breast cancer in postmenopausal women.
Journal: The Cochrane database of systematic reviews 20091007
Title: Gene expression changes in the hypothalamus provide evidence for regionally-selective changes in IL-1 and microglial markers after acute stress.
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Title: An efficient steroid pharmacophore-based strategy to identify new aromatase inhibitors.
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Title: An approach to the management of patients with residual Cushing's disease.
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Title: Regulation of sterol regulatory element-binding transcription factor 1a by human chorionic gonadotropin and insulin in cultured rat theca-interstitial cells.
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Title: In vitro kinetic properties of the Thr201Met variant of human aromatase gene CYP19A1: functional responses to substrate and product inhibition and enzyme inhibitors.
Journal: The Journal of clinical endocrinology and metabolism 20090801
Title: An updated review on the efficacy of adjuvant endocrine therapies in hormone receptor-positive early breast cancer.
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Title: History of aromatase: saga of an important biological mediator and therapeutic target.
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Title: Synthesis of casimiroin and optimization of its quinone reductase 2 and aromatase inhibitory activities.
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Title: Steroidogenesis-disrupting compounds can be effectively studied for major fertility-related endpoints using in vitro cultured mouse follicles.
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Title: Dehydroepiandrosterone and neurotrophins favor axonal growth in a sensory neuron-keratinocyte coculture model.
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Title: Ketoconazole treatment for Cushing syndrome in McCune-Albright syndrome.
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Title: Determination of aminoglutethimide enantiomers in pharmaceutical formulations by capillary electrophoresis using methylated-beta-cyclodextrin as a chiral selector and computational calculation for their respective inclusion complexes.
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Title: Sulfated and sulfonated polysaccharide as chiral stationary phases for capillary electrochromatography and capillary electrochromatography-mass spectrometry.
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Title: Glucocorticoid inhibition in the treatment of depression: can we think outside the endocrine hypothalamus?
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Title: Targeting angiogenesis-dependent calcified neoplasms using combined polymer therapeutics.
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Title: Using molecular similarity to highlight the challenges of routine immunoassay-based drug of abuse/toxicology screening in emergency medicine.
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Title: Antiproliferative effect of exemestane in lung cancer cells.
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Title: Enhanced Interaction between Warfarin and High-Dose Ketoconazole: A Case Report.
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Title: Role of neo-adjuvant hormonal therapy in the treatment of breast cancer: a review of clinical trials.
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Title: Male breast cancer: a review.
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Title: The evolution of treatment for early breast cancer: what's next?
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Title: Predisposing factors for fibroids and outcome of laparoscopic myomectomy in infertility.
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Title: Aromatase inhibitors, efficacy and metabolic risk in the treatment of postmenopausal women with early breast cancer.
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Title: Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
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Title: Secretion of cortisol and aldosterone as a vulnerable target for adrenal endocrine disruption - screening of 30 selected chemicals in the human H295R cell model.
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Title: Screening of herbal constituents for aromatase inhibitory activity.
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Title: Synthesis of 6- or 4-functionalized indoles via a reductive cyclization approach and evaluation as aromatase inhibitors.
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Title: Progesterone stimulates the proliferation of female and male cholangiocytes via autocrine/paracrine mechanisms.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20080701
Title: Xanthones from the botanical dietary supplement mangosteen (Garcinia mangostana) with aromatase inhibitory activity.
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Title: Synthesis and hypnotic activities of N-Cbz-alpha-aminoglutarimidooxy carboxylate derivatives.
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Title: Regulatory role of cytochrome P450scc and pregnenolone in myelination by rat Schwann cells.
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Title: Prolonged remission of severe Cushing syndrome without adrenalectomy in an infant with McCune-Albright syndrome.
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Title: Nitric oxide stimulates the production of atrial natriuretic peptide and progesterone by human granulosa luteinized cells with an antiapoptotic effect.
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Title: CYP1B1 is not a major determinant of the disposition of aromatase inhibitors in epithelial cells of invasive ductal carcinoma.
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Title: Mono-(2-ethylhexyl) phthalate stimulates basal steroidogenesis by a cAMP-independent mechanism in mouse gonadal cells of both sexes.
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Title: New selective inhibitors of steroid 11beta-hydroxylation in the adrenal cortex. Synthesis and structure-activity relationship of potent etomidate analogues.
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Title: Anti-inflammatory effect of theophylline in rats and its involvement of the glucocorticoid-glucocorticoid receptor system.
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Title: Cyclin D1 expression in breast cancer patients receiving adjuvant tamoxifen-based therapy.
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Title: Neuroprogesterone: key to estrogen positive feedback?
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Title: Intrathecally injected morphine inhibits inflammatory paw edema: the involvement of nitric oxide and cyclic-guanosine monophosphate.
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Title: Aromatase inhibitors: assessment of biochemical efficacy measured by total body aromatase inhibition and tissue estrogen suppression.
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Title: Long-term safety of aromatase inhibitors in the treatment of breast cancer.
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Title: Aromatase inhibitors: past, present and future in breast cancer therapy.
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Title: [Medical treatment for Cushing's syndrome].
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Title: The use of interim data and Data Monitoring Committee recommendations in randomized controlled trial reports: frequency, implications and potential sources of bias.
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Title: Systematic review of the clinical effect of glucocorticoids on nonhematologic malignancy.
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Title: Use of letrozole in assisted reproduction: a systematic review and meta-analysis.
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Title: A dramatic, objective antiandrogen withdrawal response: case report and review of the literature.
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Title: Steroid biosynthesis inhibitors in the therapy of hypercortisolism: theory and practice.
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Title: Strength and weakness of phase I to IV trials, with an emphasis on translational aspects.
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Title: Antioxidant systems and oxidative stress in the testes.
Journal: Oxidative medicine and cellular longevity 20080101
Title: Extended adjuvant therapy for breast cancer--how much is enough?
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Title: Extended adjuvant therapy with anastrozole among postmenopausal breast cancer patients: results from the randomized Austrian Breast and Colorectal Cancer Study Group Trial 6a.
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Title: The what, why and how of aromatase inhibitors: hormonal agents for treatment and prevention of breast cancer.
Journal: International journal of clinical practice 20071201
Title: Combining computational and biochemical studies for a rationale on the anti-aromatase activity of natural polyphenols.
Journal: ChemMedChem 20071201
Title: Nodular pulmonary histoplasmosis in Cushing's disease: a case report and literature review.
Journal: Tennessee medicine : journal of the Tennessee Medical Association 20071201
Title: Advanced age and high initial WBC influence the outcome of inv(3) (q21q26)/t(3;3) (q21;q26) positive AML.
Journal: Leukemia & lymphoma 20071101
Title: Letrozole in advanced breast cancer: the PO25 trial.
Journal: Breast cancer research and treatment 20071001
Title: The early days of letrozole.
Journal: Breast cancer research and treatment 20071001
Title: The discovery and mechanism of action of letrozole.
Journal: Breast cancer research and treatment 20071001
Title: A decade of letrozole: FACE.
Journal: Breast cancer research and treatment 20071001
Title: The patient experience.
Journal: Breast cancer research and treatment 20071001
Title: The effects of aromatase inhibitors and selective estrogen receptor modulators on eye development in the zebrafish (Danio rerio).
Journal: Current eye research 20071001
Title: Inhibitory effects of pharmacological doses of melatonin on aromatase activity and expression in rat glioma cells.
Journal: British journal of cancer 20070911
Title: PTGER1 and PTGER2 receptors mediate regulation of progesterone synthesis and type 1 11beta-hydroxysteroid dehydrogenase activity by prostaglandin E2 in human granulosa lutein cells.
Journal: The Journal of endocrinology 20070901
Title: The influence of di-(2-ethylhexyl) phthalate on steroidogenesis by the ovarian granulosa cells of immature female rats.
Journal: The Journal of endocrinology 20070901
Title: Nanomolar concentrations of anabolic-androgenic steroids amplify excitotoxic neuronal death in mixed mouse cortical cultures.
Journal: Brain research 20070824
Title: An alpha-fetoprotein-derived peptide reduces the uterine hyperplasia and increases the antitumour effect of tamoxifen.
Journal: British journal of cancer 20070806
Title: Dehydroepiandrosterone protects vascular endothelial cells against apoptosis through a Galphai protein-dependent activation of phosphatidylinositol 3-kinase/Akt and regulation of antiapoptotic Bcl-2 expression.
Journal: Endocrinology 20070701
Title: Aminoglutethimide-induced protein free radical formation on myeloperoxidase: a potential mechanism of agranulocytosis.
Journal: Chemical research in toxicology 20070701
Title: Synthesis and biological evaluation of (+/-)-abyssinone II and its analogues as aromatase inhibitors for chemoprevention of breast cancer.
Journal: Journal of medicinal chemistry 20070614
Title: Pharmacological therapy of Cushing's syndrome: drugs and indications.
Journal: Mini reviews in medicinal chemistry 20070501
Title: Luteinizing hormone-induced caspase activation in rat preovulatory follicles is coupled to mitochondrial steroidogenesis.
Journal: Endocrinology 20070401
Title: Effects of aromatase inhibitors on human osteoblast and osteoblast-like cells: a possible androgenic bone protective effects induced by exemestane.
Journal: Bone 20070401
Title: Physiological testosterone stimulates tissue plasminogen activator and tissue factor pathway inhibitor and inhibits plasminogen activator inhibitor type 1 release in endothelial cells.
Journal: Biochemistry and cell biology = Biochimie et biologie cellulaire 20070401
Title: Switching to an aromatase inhibitor provides mortality benefit in early breast carcinoma: pooled analysis of 2 consecutive trials.
Journal: Cancer 20070315
Title: Glucocorticoid feedback control of corticotropin in the hypoxic neonatal rat.
Journal: The Journal of endocrinology 20070201
Title: Aromatase inhibitors for treatment of advanced breast cancer in postmenopausal women.
Journal: The Cochrane database of systematic reviews 20070124
Title: Investigating the mechanism of enhanced cytotoxicity of HPMA copolymer-Dox-AGM in breast cancer cells.
Journal: Journal of controlled release : official journal of the Controlled Release Society 20070122
Title: Validation and application of a screening method for beta2-agonists, anti-estrogenic substances and mesocarb in human urine using liquid chromatography/tandem mass spectrometry.
Journal: Rapid communications in mass spectrometry : RCM 20070101
Title: Adrenal toxicology: a strategy for assessment of functional toxicity to the adrenal cortex and steroidogenesis.
Journal: Journal of applied toxicology : JAT 20070101
Title: Is pseudo-Cushing's syndrome in a critically ill patient 'pseudo'? Hypothesis and supportive case report.
Journal: Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 20070101
Title: Simultaneous ectopic adrenocorticotropic hormone syndrome and adrenal metastasis of a medullary thyroid carcinoma causing paraneoplastic Cushing's syndrome.
Journal: International seminars in surgical oncology : ISSO 20070101
Title: Medical management of Cushing disease.
Journal: Neurosurgical focus 20070101
Title: Treatment algorithm in hormone-resistant prostate cancer: Practical guidelines.
Journal: Indian journal of urology : IJU : journal of the Urological Society of India 20070101
Title: Role of corticosterone in immunosuppressive effects of acute ethanol exposure on Toll-like receptor mediated cytokine production.
Journal: Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 20061201
Title: Human adrenocarcinoma (H295R) cells for rapid in vitro determination of effects on steroidogenesis: hormone production.
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Title: The H295R system for evaluation of endocrine-disrupting effects.
Journal: Ecotoxicology and environmental safety 20061101
Title: Inhibition of rainbow trout (Oncorhynchus mykiss) P450 aromatase activities in brain and ovarian microsomes by various environmental substances.
Journal: Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20061101
Title: Hypothermic preconditioning reduces Purkinje cell death possibly by preventing the over-expression of inducible nitric oxide synthase in rat cerebellar slices after an in vitro simulated ischemia.
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Title: Effects of aromatase inhibitors on in vitro steroidogenesis by Atlantic salmon (Salmo salar) gonadal and brain tissue.
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Title: Survival with aromatase inhibitors and inactivators versus standard hormonal therapy in advanced breast cancer: meta-analysis.
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Title: Relationship between steroidogenesis and spermiation in Rana catesbeiana and Leptodactylus ocellatus.
Journal: Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 20060801
Title: Progesterone regulation of the expression and function of multidrug resistance type I in porcine granulosa cells.
Journal: Reproductive toxicology (Elmsford, N.Y.) 20060701
Title: An alternative pathway of vitamin D metabolism. Cytochrome P450scc (CYP11A1)-mediated conversion to 20-hydroxyvitamin D2 and 17,20-dihydroxyvitamin D2.
Journal: The FEBS journal 20060701
Title: Second- and third-generation aromatase inhibitors as first-line endocrine therapy in postmenopausal metastatic breast cancer patients: a pooled analysis of the randomised trials.
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Title: The role of glucocorticoids in the uncontrollable stress-induced potentiation of nucleus accumbens shell dopamine and conditioned place preference responses to morphine.
Journal: Psychoneuroendocrinology 20060601
Title: Future prospects in depression research.
Journal: Dialogues in clinical neuroscience 20060601
Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.
Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
Title: Aminoglutethimide prevents excitotoxic and ischemic injuries in cortical neurons.
Journal: British journal of pharmacology 20060401
Title: Implication of glucocorticoid in anti-inflammatory effects of Ro5-4864 in mouse pleurisy induced by carrageenan.
Journal: Life sciences 20060313
Title: Synthesis and biological evaluation of 5-[(aryl)(1H-imidazol-1-yl)methyl]-1H-indoles: potent and selective aromatase inhibitors.
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Title: [Effects of drugs on the adrenal cortex and its tumors].
Journal: Der Pathologe 20060201
Title: Melatonin inhibits the growth of DMBA-induced mammary tumors by decreasing the local biosynthesis of estrogens through the modulation of aromatase activity.
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Title: Secondary hormonal therapy for advanced prostate cancer.
Journal: The Journal of urology 20060101
Title: Studies of the role of steroid hormone in the regulation of oocyte maturation in cattle.
Journal: Reproductive biology and endocrinology : RB&E 20060101
Title: [Testosterone inhibits the contractile responses to phenylephrine associated with the release of intracellular calcium in rat aorta].
Journal: Gaceta medica de Mexico 20060101
Title: A proposed mechanism for progesterone regulation of trophoblast MMP2 transcription independent of classical progesterone response elements on its promoter.
Journal: Journal of experimental & clinical assisted reproduction 20060101
Title: The role of steroids in follicular growth.
Journal: Reproductive biology and endocrinology : RB&E 20060101
Title: Non-hormonal systemic therapy in men with hormone-refractory prostate cancer and metastases: a systematic review from the Cancer Care Ontario Program in Evidence-based Care's Genitourinary Cancer Disease Site Group.
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Title: Simple tandem repeat (TTTA)n polymorphism in CYP19 (aromatase) gene and breast cancer risk in Nigerian women.
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Title: Efficacy and tolerability of high dose 'ethinylestradiol' in post-menopausal advanced breast cancer patients heavily pre-treated with endocrine agents.
Journal: World journal of surgical oncology 20060101
Title: Dehydroepiandrosterone restoration of growth hormone gene expression in aging female rats, in vivo and in vitro: evidence for actions via estrogen receptors.
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Title: Melatonin enhances the inhibitory effect of aminoglutethimide on aromatase activity in MCF-7 human breast cancer cells.
Journal: Breast cancer research and treatment 20051201
Title: Effect of progesterone on the expression of bax and bcl-2 and on caspase activity in bovine luteal cells.
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Title: Role of adrenalectomy in ectopic ACTH syndrome.
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Title: Neuroendocrine predictors of the evolution of depression.
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Title: Bone loss and the aromatase inhibitors.
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Title: Aminoglutethimide but not spironolactone enhances the anticonvulsant effect of some antiepileptics against amygdala-kindled seizures in rats.
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Title: Letrozole in the treatment of breast cancer.
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Title: Polymer therapeutics designed for a combination therapy of hormone-dependent cancer.
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Title: Influence of aminoglutethimide and spironolactone on the efficacy of carbamazepine and diphenylhydantoin against amygdala-kindled seizures in rats.
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Title: Synthesis and characterization of azole isoflavone inhibitors of aromatase.
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Title: Secondary hormonal manipulations in the management of advanced prostate cancer.
Journal: The Canadian journal of urology 20050601
Title: Changes in peripheral benzodiazepine receptors in patients with bipolar disorder.
Journal: Neuropsychiatric disease and treatment 20050601
Title: Surgical and pharmacological suppression of glucocorticoids prevents the enhancement of morphine conditioned place preference by uncontrollable stress in rats.
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Title: Evidence for a spinal serotonergic control of the peripheral inflammation in the rat.
Journal: Life sciences 20050401
Title: Synthesis and study of some new N-substituted imide derivatives as potential anticancer agents.
Journal: Farmaco (Societa chimica italiana : 1989) 20050401
Title: Benzofuran- and furan-2-yl-(phenyl)-3-pyridylmethanols: synthesis and inhibition of P450 aromatase.
Journal: Journal of enzyme inhibition and medicinal chemistry 20050401
Title: Synthesis and anti-aromatase activity of some new steroidal D-lactones.
Journal: Steroids 20050101
Title: The role of aromatase inhibitors in ameliorating deleterious effects of ovarian stimulation on outcome of infertility treatment.
Journal: Reproductive biology and endocrinology : RB&E 20050101
Title: HPMA copolymer-aminoglutethimide conjugates inhibit aromatase in MCF-7 cell lines.
Journal: Journal of drug targeting 20050101
Title: 2- and 3-[(aryl)(azolyl)methyl]indoles as potential non-steroidal aromatase inhibitors.
Journal: Journal of enzyme inhibition and medicinal chemistry 20041201
Title: Toward the development of a cephalosporin-based dual-release prodrug for use in ADEPT.
Journal: The Journal of organic chemistry 20041112
Title: Steroid-free medium discloses oestrogenic effects of the bisphosphonate clodronate on breast cancer cells.
Journal: British journal of cancer 20041101
Title: Randomised phase III study of intravenous vinorelbine plus hormone therapy versus hormone therapy alone in hormone-refractory prostate cancer.
Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20041101
Title: Effect of combination therapy with aminoglutethimide and hydrocortisone on prostate-specific antigen response in metastatic prostate cancer refractory to standard endocrine therapy.
Journal: Anti-cancer drugs 20041001
Title: Use of aromatase inhibitors in children with short stature.
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Title: Inhibition of ossification in vivo and differentiation of osteoblasts in vitro by tributyltin.
Journal: Biochemical pharmacology 20040815
Title: Methadone metabolism by human placenta.
Journal: Biochemical pharmacology 20040801
Title: Chiral resolution of some piperidine 2, 6-dione drugs by high performance liquid chromatography on Kromasil CHI-DMB column.
Journal: Archiv der Pharmazie 20040801
Title: Synthesis and aromatase inhibitory activity of novel pyridine-containing isoflavones.
Journal: Journal of medicinal chemistry 20040729
Title: Acute effects of testosterone on intracellular Ca2+ kinetics in rat coronary endothelial cells are exerted via aromatization to estrogens.
Journal: American journal of physiology. Heart and circulatory physiology 20040701
Title: Synthesis and evaluation of a dimer of 2-(4-pyridylmethyl)-1-indanone as a novel nonsteroidal aromatase inhibitor.
Journal: Archiv der Pharmazie 20040701
Title: Aminoglutethimide included in nanocapsules suspension: comparison of GC-MS and HPLC methods for control.
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Title: Hormonal impact of the 17alpha-hydroxylase/C(17,20)-lyase inhibitor abiraterone acetate (CB7630) in patients with prostate cancer.
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Title: Aromatase inhibition in the treatment of advanced breast cancer: is there a relationship between potency and clinical efficacy?
Journal: British journal of cancer 20040504
Title: Upregulation of steroidogenic enzymes and ovarian 17beta-estradiol in human granulosa-lutein cells by Cordyceps sinensis mycelium.
Journal: Biology of reproduction 20040501
Title: The estrogen suppression after sequential treatment with formestane in advanced breast cancer patients.
Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20040501
Title: Antinociceptive effects of peripheral benzodiazepine receptors.
Journal: Pharmacology 20040401
Title: Involvement of steroids in anti-inflammatory effects of PK11195 in a murine model of pleurisy.
Journal: Mediators of inflammation 20040401
Title: Prostate cancer metastasis to supraclavicular lymph node.
Journal: Clinical advances in hematology & oncology : H&O 20040401
Title: Oestrogen suppression--lessons from clinical studies.
Journal: Best practice & research. Clinical endocrinology & metabolism 20040301
Title: Aromatase inhibitors: new endocrine treatment of breast cancer.
Journal: Seminars in reproductive medicine 20040201
Title: Involvement of steroids in anti-inflammatory effects of peripheral benzodiazepine receptor ligands.
Journal: Life sciences 20040130
Title: The glucocorticoid receptor mediates the thymic epithelial cell-induced apoptosis of CD4+8+ thymic lymphoma cells.
Journal: Cellular immunology 20040101
Title: Cancer of the endometrium: current aspects of diagnostics and treatment.
Journal: World journal of surgical oncology 20040101
Title: Immature rats show ovulatory defects similar to those in adult rats lacking prostaglandin and progesterone actions.
Journal: Reproductive biology and endocrinology : RB&E 20040101
Title: Endocrinology and hormone therapy in breast cancer: aromatase inhibitors versus antioestrogens.
Journal: Breast cancer research : BCR 20040101
Title: Role of secondary hormonal therapy in the management of recurrent prostate cancer.
Journal: Urology 20031229
Title: Aminoglutethimide-induced leucopenia in a mouse model: effects of metabolic and structural determinates.
Journal: Environmental toxicology and pharmacology 20031201
Title: Aromatase inhibitors in breast cancer.
Journal: The New England journal of medicine 20030911
Title: Aromatase is the major enzyme metabolizing buprenorphine in human placenta.
Journal: The Journal of pharmacology and experimental therapeutics 20030901
Title: Professor Tom Connors and the development of novel cancer therapies by the Phase I/II Clinical Trials Committee of Cancer Research UK.
Journal: British journal of cancer 20030804
Title: Growth retardation as well as spleen and thymus involution in latent TGF-beta binding protein (Ltbp)-3 null mice.
Journal: Journal of cellular physiology 20030801
Title: Corticosterone enhances adrenocorticotropin-induced calcium signals in bovine adrenocortical cells.
Journal: Endocrinology 20030801
Title: Ff1b is required for the development of steroidogenic component of the zebrafish interrenal organ.
Journal: Developmental biology 20030801
Title: A comparison of the efficacy of aromatase inhibitors in second-line treatment of metastatic breast cancer.
Journal: American journal of clinical oncology 20030801
Title: Applicability of the intratumor aromatase preclinical model to predict clinical trial results with endocrine therapy.
Journal: American journal of clinical oncology 20030801
Title: The role of aromatase inhibitors in the treatment of metastatic breast cancer.
Journal: Seminars in oncology 20030801
Title: Expression of 11beta-hydroxysteroid dehydrogenase (11betaHSD) proteins in luteinizing human granulosa-lutein cells.
Journal: The Journal of endocrinology 20030701
Title: Antidepressant-like effect of Ro5-4864, a peripheral-type benzodiazepine receptor ligand, in forced swimming test.
Journal: European journal of pharmacology 20030613
Title: Preparation and pharmacological profile of 7-(alpha-azolylbenzyl)-1H-indoles and indolines as new aromatase inhibitors.
Journal: Bioorganic & medicinal chemistry letters 20030505
Title: Could exemestane affect insulin-like growth factors, interleukin 6 and bone metabolism in postmenopausal advanced breast cancer patients after failure on aminoglutethimide, anastrozole or letrozole?
Journal: International journal of oncology 20030501
Title: Reversal of cycloheximide-induced memory disruption by AIT-082 (Neotrofin) is modulated by, but not dependent on, adrenal hormones.
Journal: Psychopharmacology 20030401
Title: Update on the current use of hormonals as therapy in advanced breast cancer.
Journal: Anti-cancer drugs 20030401
Title: Stereoselective determination of pyridoglutethimide enantiomers in serum with a chiral cellulose-based high-performance liquid chromatographic column using solid phase extraction and UV detection.
Journal: Journal of pharmaceutical and biomedical analysis 20030401
Title: Randomized trial of tamoxifen versus tamoxifen plus aminoglutethimide as adjuvant treatment in postmenopausal breast cancer patients with hormone receptor-positive disease: Austrian breast and colorectal cancer study group trial 6.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20030315
Title: Acute ethanol administration profoundly alters poly I:C-induced cytokine expression in mice by a mechanism that is not dependent on corticosterone.
Journal: Life sciences 20030307
Title: Stimulatory effect of progesterone on the expression of steroidogenic acute regulatory protein in MA-10 Leydig cells.
Journal: Biology of reproduction 20030301
Title: The therapeutic potential of aromatase inhibitors.
Journal: Expert opinion on investigational drugs 20030301
Title: Aromatase inhibitors as adjuvant therapy in breast cancer.
Journal: Oncology (Williston Park, N.Y.) 20030301
Title: A spinal mechanism for the peripheral anti-inflammatory action of indomethacin.
Journal: Brain research 20030207
Title: Anandamide activity and degradation are regulated by early postnatal aging and follicle-stimulating hormone in mouse Sertoli cells.
Journal: Endocrinology 20030101
Title: Long-term survival of patients given hormonal therapy for metastatic endometrial stromal sarcoma.
Journal: Medical oncology (Northwood, London, England) 20030101
Title: The adrenal cortex and steroidogenesis as cellular and molecular targets for toxicity: critical omissions from regulatory endocrine disrupter screening strategies for human health?
Journal: Journal of applied toxicology : JAT 20030101
Title: [Maturation of the follicle-enclosed common frog oocytes stimulated by low progesterone concentrations depends on transcription].
Journal: Ontogenez 20030101
Title: [Effects of cycloheximide, aminoglutethimide, indomethacin, cytochalasin B and colchicine on ovulation and the ultrastructure of the ovarian follicle wall in the stellate sturgeon Acipenser stellatus Pall].
Journal: Ontogenez 20030101
Title: Breast cancer patients with bone metastases are characterised by increased levels of nonisomerised type I collagen fragments.
Journal: Breast cancer research : BCR 20030101
Title: Medical treatment of hyperadrenocorticism in the dog.
Journal: Australian veterinary journal 20030101
Title: Elevation of soluble tumor necrosis factor receptor II in non-febrile patients with acute myeloid leukemia.
Journal: European journal of medical research 20021125
Title: Exemestane: treatment of breast cancer with selective inactivation of aromatase.
Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20021115
Title: A phase II study of cisplatin and vinorelbine in patients with metastatic breast cancer.
Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20021101
Title: Design, synthesis and evaluation of 4-imidazolylflavans as new leads for aromatase inhibition.
Journal: Bioorganic & medicinal chemistry letters 20021021
Title: The evolving role of aromatase inhibitors in breast cancer.
Journal: International journal of clinical oncology 20021001
Title: Design, synthesis, and evaluation of 4-(4'-aminobenzyl)-2-oxazolidinones as novel inhibitors of the cytochrome P-450 enzyme aromatase.
Journal: Bioorganic chemistry 20021001
Title: Secondary hormonal therapies in the treatment of prostate cancer.
Journal: Urology 20020901
Title: Glucocorticoids enhance activation of the human type II 3beta-hydroxysteroid dehydrogenase/Delta5-Delta4 isomerase gene.
Journal: The Journal of steroid biochemistry and molecular biology 20020901
Title: Enantiomeric separations using poly(L-valine) and poly(L-leucine) surfactants. Investigation of steric factors near the chiral center.
Journal: Journal of chromatography. A 20020809
Title: Placental endocrine disruption induced by cadmium: effects on P450 cholesterol side-chain cleavage and 3beta-hydroxysteroid dehydrogenase enzymes in cultured human trophoblasts.
Journal: Biology of reproduction 20020701
Title: FSH and LH induce progesterone production and progesterone receptor synthesis in cumulus cells: a requirement for meiotic resumption in porcine oocytes.
Journal: Molecular human reproduction 20020701
Title: 11beta-Hydroxysteroid dehydrogenase types 1 and 2 are up- and downregulated in cortisol-secreting adrenal adenomas.
Journal: Journal of investigative medicine : the official publication of the American Federation for Clinical Research 20020701
Title: Aromatase inhibitors in breast cancer: current and evolving roles.
Journal: Cleveland Clinic journal of medicine 20020701
Title: Novel oxazolidinone based compounds as inhibitors of aromatase and the use of the substrate-heme complex approach in the rationalisation of these compounds.
Journal: Biochemical and biophysical research communications 20020607
Title: Erratum to 'CNS drugs in Cushing's disease: pathophysiological and therapeutic implications for mood disorders' [Prog. Neuro-Psycol. Biol. Psychiatry, 26, 763 (2002)].
Journal: Progress in neuro-psychopharmacology & biological psychiatry 20020601
Title: LC determination of aminoglutethimide enantiomers as dansyl and fluorescamine derivatives in tablet formulations.
Journal: Journal of pharmaceutical and biomedical analysis 20020515
Title: Residual symptoms in depression an emerging therapeutic concept.
Journal: Progress in neuro-psychopharmacology & biological psychiatry 20020501
Title: Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.
Journal: The Journal of biological chemistry 20020419
Title: New aromatase inhibitors. Synthesis and inhibitory activity of pyridinyl-substituted flavanone derivatives.
Journal: Bioorganic & medicinal chemistry letters 20020408
Title: Effects of 3-MeSO2-DDE and some CYP inhibitors on glucocorticoid steroidogenesis in the H295R human adrenocortical carcinoma cell line.
Journal: Toxicology in vitro : an international journal published in association with BIBRA 20020401
Title: [The role of aromatase inhibitors in the treatment of breast neoplasms. An evaluation of clinical efficacy and the tolerability profile].
Journal: Minerva ginecologica 20020401
Title: Aromatase inhibitors in breast cancer therapy.
Journal: Expert review of anticancer therapy 20020401
Title: Approval summary: letrozole in the treatment of postmenopausal women with advanced breast cancer.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20020301
Title: Use of aminoglutethimide in the treatment of pituitary-dependent hyperadrenocorticism in the dog.
Journal: The Journal of small animal practice 20020301
Title: Synthesis and aromatase inhibitory activity of flavanones.
Journal: Pharmaceutical research 20020301
Title: Testosterone-induced vasorelaxation in the rat mesenteric arterial bed is mediated predominantly via potassium channels.
Journal: British journal of pharmacology 20020201
Title: Tamoxifen resistant and refractory breast cancer: the value of aromatase inhibitors.
Journal: Drugs 20020101
Title: Endocrine and clinical endpoints of exemestane as neoadjuvant therapy.
Journal: Cancer control : journal of the Moffitt Cancer Center 20020101
Title: Cholesterol transport, peripheral benzodiazepine receptor, and steroidogenesis in aging Leydig cells.
Journal: Journal of andrology 20020101
Title: Ectopic ACTH-syndrome due to a thymic carcinoid tumor.
Journal: Acta clinica Belgica 20020101
Title: Estrogen as therapy for breast cancer.
Journal: Breast cancer research : BCR 20020101
Title: Identification of the aromatase inhibitor aminoglutethimide in urine by gas chromatography/mass spectrometry.
Journal: Rapid communications in mass spectrometry : RCM 20020101
Title: Aromatase inhibitors in breast cancer: an update.
Journal: Cancer control : journal of the Moffitt Cancer Center 20020101
Title: Interactions of antioestrogens and aromatase inhibitors.
Journal: Forum (Genoa, Italy) 20020101
Title: Medical therapy of Cushing's disease.
Journal: Pituitary 20020101
Title: Classic and recent etiologies of Cushing's syndrome: diagnosis and therapy.
Journal: Treatments in endocrinology 20020101
Title: Differential role of PR-A and -B isoforms in transcription regulation of human GnRH receptor gene.
Journal: Molecular endocrinology (Baltimore, Md.) 20011201
Title: Relationship between the production of prostaglandins and progesterone by luteinizing human granulosa cells.
Journal: The Journal of endocrinology 20011201
Title: High dehydroepiandrosterone-sulfate predicts breast cancer progression during new aromatase inhibitor therapy and stimulates breast cancer cell growth in tissue culture: a renewed role for adrenalectomy.
Journal: Surgery 20011201
Title: A summary of second-line randomized studies of aromatase inhibitors.
Journal: The Journal of steroid biochemistry and molecular biology 20011201
Title: Adjuvant trials of aromatase inhibitors: determining the future landscape of adjuvant endocrine therapy.
Journal: The Journal of steroid biochemistry and molecular biology 20011201
Title: Where do selective estrogen receptor modulators (SERMs) and aromatase inhibitors (AIs) now fit into breast cancer treatment algorithms?
Journal: The Journal of steroid biochemistry and molecular biology 20011201
Title: The role of tamoxifen and aromatase inhibitors/inactivators in postmenopausal patients.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20011201
Title: Are differences in the available aromatase inhibitors and inactivators significant?
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20011201
Title: Sequential tamoxifen and aminoglutethimide versus tamoxifen alone in the adjuvant treatment of postmenopausal breast cancer patients: results of an Italian cooperative study.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20011115
Title: Aromatase inhibitors from Broussonetia papyrifera.
Journal: Journal of natural products 20011001
Title: Acute stress-induced facilitation of the hypothalamic-pituitary-adrenal axis: evidence for the roles of stressor duration and serotonin.
Journal: Neuroendocrinology 20010901
Title: Primary culture system of adrenocortical cells from dogs to evaluate direct effects of chemicals on steroidogenesis.
Journal: Toxicology 20010828
Title: New D-modified androstane derivatives as aromatase inhibitors.
Journal: Steroids 20010801
Title: Different catalytic properties and inhibitor responses of the goldfish brain and ovary aromatase isozymes.
Journal: General and comparative endocrinology 20010801
Title: Nonsteroidal and steroidal aromatase inhibitors in breast cancer.
Journal: Oncology (Williston Park, N.Y.) 20010801
Title: Induction of atypical ductal hyperplasia in mouse mammary gland organ culture.
Journal: Journal of the National Cancer Institute 20010718
Title: Cytotoxic treatment of adrenocortical carcinoma.
Journal: World journal of surgery 20010701
Title: Aromatase inhibitors: past, present and future.
Journal: Molecular and cellular endocrinology 20010610
Title: Aromatase inhibition by an 11,13-dihydroderivative of a sesquiterpene lactone.
Journal: The Journal of pharmacology and experimental therapeutics 20010601
Title: Expression of messenger RNA for gonadotropin receptor in the granulosa layer during the ovulatory cycle of hens.
Journal: Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20010601
Title: Aryl hydrocarbon receptor (AhR)-linked inhibition of luteal cell progesterone secretion in 2,3,7,8-tetrachlorodibenzo-p-dioxin treated cells.
Journal: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20010601
Title: Luteinization factor-stimulated steroidogenesis in porcine granulosa cells.
Journal: General physiology and biophysics 20010601
Title: Cold-induced increment in rat adrenal gland type II deiodinase is corticosterone dependent.
Journal: Endocrine 20010601
Title: Contribution of progesterone, follicle stimulating hormone and glucocorticoids in survival of serum-free cultured granulosa cell explants.
Journal: The Journal of endocrinology 20010501
Title: Enantioseparation of aminoglutethimide and thalidomide by high performance liquid chromatography or supercritical fluid chromatography on mono-2 and mono-6-O-pentenyl-beta-cyclodextrin-based chiral stationary phases.
Journal: Biomedical chromatography : BMC 20010501
Title: ACTH-receptor expression, regulation and role in adrenocortial tumor formation.
Journal: European journal of endocrinology 20010301
Title: A new class of nonsteroidal aromatase inhibitors: design and synthesis of chromone and xanthone derivatives and inhibition of the P450 enzymes aromatase and 17 alpha-hydroxylase/C17,20-lyase.
Journal: Journal of medicinal chemistry 20010301
Title: Aminoglutethimide, a steroidogenesis inhibitor, abolishes hormonal induction of ornithine decarboxylase in steroidogenic tissues: evidence for its role as cAMP-dependent protein kinase inhibitor.
Journal: Biochemical and biophysical research communications 20010216
Title: Periovulatory changes in catfish ovarian oestradiol-17beta, oestrogen-2-hydroxylase and catechol-O-methyltransferase during GnRH analogue-induced ovulation and in vitro induction of oocyte maturation by catecholoestrogens.
Journal: The Journal of endocrinology 20010201
Title: Synthesis, evaluation and QSAR studies of highly potent aromatase inhibitors of the piperidinedione type.
Journal: Anti-cancer drug design 20010201
Title: Evaluation of the mechanism of aromatase cytochrome P450. A site-directed mutagenesis study.
Journal: European journal of biochemistry 20010101
Title: [Modern approaches to hormone therapy of breast cancer as a reflection of pathogenesis of the disease].
Journal: Voprosy onkologii 20010101
Title: Psychiatric disorders associated with Cushing's syndrome. Epidemiology, pathophysiology and treatment.
Journal: CNS drugs 20010101
Title: Aromatase, aromatase inhibitors, and breast cancer.
Journal: American journal of therapeutics 20010101
Title: Lipoproteins regulate expression of the steroidogenic acute regulatory protein (StAR) in mouse adrenocortical cells.
Journal: The Journal of biological chemistry 20001124
Title: Antiandrogen withdrawal syndrome associated with prostate cancer therapies: incidence and clinical significance.
Journal: Drug safety 20001101
Title: PRAP, a prolactin receptor associated protein: its gene expression and regulation in the corpus luteum.
Journal: Endocrinology 19970801
Title: Exploration for drug therapy in endometrial carcinoma.
Journal: Chinese medical journal 19960501
Title: [Comparison between the roles of aminoglutethimide and hydroxyprogesterone caproates in the treatment of endometrial cancer].
Journal: Zhonghua fu chan ke za zhi 19950801
Title: Methotrexate induced brain necrosis and severe leukoencephalopathy due to disconnection of an Ommaya device.
Journal: Journal of neuro-oncology 19930301
Title: The effect of the aromatase inhibitor, rogletimide (pyridoglutethimide), on guinea pig adrenal cell steroidogenesis and placental microsomal aromatase activity: comparison with aminoglutethimide and CGS 16949A.
Journal: The Journal of steroid biochemistry and molecular biology 19911101
Title: Fadrozole hydrochloride: a potent, selective, nonsteroidal inhibitor of aromatase for the treatment of estrogen-dependent disease.
Journal: Journal of medicinal chemistry 19910201
Title: Androgen depletion and repletion as a means of potentiating the effect of cytotoxic chemotherapy in advanced prostate cancer.
Journal: Journal of steroid biochemistry 19870101
Title: Inappropriate secretion of antidiuretic hormone following aminoglutethimide therapy.
Journal: British journal of urology 19861201
Title: Hormone stimulation and chemotherapy in advanced prostate cancer: interim analysis of an ongoing randomized trial.
Journal: Anticancer research 19860101
Title: Hormone stimulation and chemotherapy in advanced prostate cancer: preliminary results of a prospective controlled clinical trial.
Journal: Anticancer research 19850101
Title: Aminoglutethimide and cholestasis.
Journal: Annals of internal medicine 19840101
Title: Treatment of advanced breast cancer with aminoglutethimide after therapy with tamoxifen.
Journal: Cancer 19821101
Title: Phase II study of aminoglutethimide and medroxyprogesterone acetate in the treatment of patients with advanced breast cancer.
Journal: Cancer research 19820801
Title: Cholestatic jaundice and aminoglutethimide.
Journal: Annals of internal medicine 19820701
Title: [Treatment of metastasizing breast cancer with aminoglutethimide].
Journal: Acta medica Austriaca 19820101
Title: [Aminoglutethimide in metastasizing carcinoma of the breast resistant to hormonal and cytostatic treatment (author's transl)].
Journal: Deutsche medizinische Wochenschrift (1946) 19811002
Title: Medical adrenalectomy with aminoglutethimide-cortisol in the treatment of metastatic breast carcinoma.
Journal: European journal of cancer 19800101
Title: Mineralocorticoid hypertension in childhood.
Journal: Mayo Clinic proceedings 19770501
Title: Evidence for an unidentified ACTH-induced steroid hormone causing hypertension.
Journal: The Journal of clinical endocrinology and metabolism 19761201