Home Thiazoles 130717-51-0
130717-51-0,MFCD05863931
Catalog No.:AA000US4

130717-51-0 | Methanone, [4,5-bis(4-methoxyphenyl)-2-thiazolyl](4-methyl-1-piperazinyl)-, hydrochloride (1:1)

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1mg
≥98%
in stock  
$46.00   $32.00
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5mg
≥98%
in stock  
$112.00   $78.00
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10mg
≥98%
in stock  
$199.00   $139.00
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50mg
≥98%
in stock  
$866.00   $606.00
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  • Technical Information
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA000US4
Chemical Name:
Methanone, [4,5-bis(4-methoxyphenyl)-2-thiazolyl](4-methyl-1-piperazinyl)-, hydrochloride (1:1)
CAS Number:
130717-51-0
Molecular Formula:
C23H26ClN3O3S
Molecular Weight:
459.9888
MDL Number:
MFCD05863931
SMILES:
COc1ccc(cc1)c1sc(nc1c1ccc(cc1)OC)C(=O)N1CCN(CC1)C.Cl
Properties
Computed Properties
 
Complexity:
556  
Covalently-Bonded Unit Count:
2  
Heavy Atom Count:
31  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
5  

Literature

Title: Muscle cyclo-oxygenase-2 pathway contributes to the exaggerated muscle mechanoreflex in rats with congestive heart failure.

Journal: Experimental physiology 20120801

Title: Leukotriene B(4) receptors BLT1 and BLT2 are involved in interleukin-8 production in human neutrophils induced by Trichomonas vaginalis-derived secretory products.

Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20120201

Title: The cyclooxygenase and nitric oxide synthesis/pathways mediate the inhibitory serotonergic response to the pressor effect elicited by sympathetic stimulation in long-term diabetic pithed rats.

Journal: Pharmacology 20120101

Title: Participation of cyclooxygenase pathway in the vasoconstriction induced by 5-HT in the in situ autoperfused kidney of long-term diabetic rats.

Journal: European journal of pharmacology 20110520

Title: Increase nitric oxide synthase activity in parotid glands from rats with experimental periodontitis.

Journal: Oral diseases 20101101

Title: Effects of selective and non-selective COX inhibitors on antigen-induced release of prostanoid mediators and bronchoconstriction in the isolated perfused and ventilated guinea pig lung.

Journal: Prostaglandins, leukotrienes, and essential fatty acids 20080201

Title: Dual, but not selective, COX-1 and COX-2 inhibitors, attenuate acetic acid-evoked bladder irritation in the anaesthetised female cat.

Journal: British journal of pharmacology 20060501

Title: Effects of intravenous administration of FR122047 (a selective cyclooxygenase 1 inhibitor) and FR188582 (a selective cyclooxygenase 2 inhibitor) on prostaglandin-E2-induced aqueous flare elevation in pigmented rabbits.

Journal: Ophthalmic research 20040101

Title: Differential effect of FR122047, a selective cyclo-oxygenase-1 inhibitor, in rat chronic models of arthritis.

Journal: British journal of pharmacology 20020201

Title: The analgesic effect profile of FR122047, a selective cyclooxygenase-1 inhibitor, in chemical nociceptive models.

Journal: European journal of pharmacology 20000310

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Tags:130717-51-0 Molecular Formula|130717-51-0 MDL|130717-51-0 SMILES|130717-51-0 Methanone, [4,5-bis(4-methoxyphenyl)-2-thiazolyl](4-methyl-1-piperazinyl)-, hydrochloride (1:1)