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13147-25-6,MFCD01727871
Catalog No.:AA000W6S

13147-25-6 | N-Ethyl-n-(2-hydroxyethyl)nitrosamine

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Purity
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1g
>97.0%(GC)
in stock  
$35.00   $24.00
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5g
>97.0%(GC)
in stock  
$103.00   $72.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA000W6S
Chemical Name:
N-Ethyl-n-(2-hydroxyethyl)nitrosamine
CAS Number:
13147-25-6
Molecular Formula:
C4H10N2O2
Molecular Weight:
118.1344
MDL Number:
MFCD01727871
SMILES:
OCCN(N=O)CC
Properties
Properties
 
BP:
103 °C / 3mmHg  
Form:
Liquid  
Refractive Index:
1.4710 to 1.4750  
Storage:
2-8℃;  

Computed Properties
 
Complexity:
67.1  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
8  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
3  
XLogP3:
-0.1  

Literature

Title: Phenobarbital mediates an epigenetic switch at the constitutive androstane receptor (CAR) target gene Cyp2b10 in the liver of B6C3F1 mice.

Journal: PloS one 20110101

Title: Chelation in metal intoxication.

Journal: International journal of environmental research and public health 20100701

Title: Potassium bromate enhances N-ethyl-N-hydroxyethylnitrosamine-induced kidney carcinogenesis only at high doses in Wistar rats: indication of the existence of an enhancement threshold.

Journal: Toxicologic pathology 20091201

Title: Etiology of bromate-induced cancer and possible modes of action-studies in Japan.

Journal: Toxicology 20060417

Title: Distinction of carcinogens from mutagens by induction of liver cell foci in a model for detection of initiation activity.

Journal: Cancer letters 20021215

Title: N-ethyl-N-hydroxyethylnitrosamine (EHEN)-induced renal and hepatocarcinogenesis in the tumor suppressor Tsc2 transgenic rat.

Journal: Cancer letters 20021028

Title: Down-regulation of von Hippel-Lindau protein in N-nitroso compound-induced rat non-clear cell renal tumors.

Journal: Cancer letters 20020508

Title: Microsome-mediated oxidation of N-nitrosodiethanolamine (NDELA), a bident carcinogen.

Journal: Chemical research in toxicology 20020401

Title: Strain variation in renal carcinogenesis by N-ethyl-N-hydroxyethylnitrosamine in F1 (Wistar-Fischer) rats.

Journal: Cancer letters 20010920

Title: Establishment and characterization of three new rat renal cell carcinoma cell lines from N-ethyl-N-hydroxyethylnitrosamine-induced basophilic cell tumors.

Journal: Pathology international 20010201

Title: Specific genomic alterations in rat renal cell carcinomas induced by N-ethyl-N-hydroxyethylnitrosamine.

Journal: Toxicologic pathology 20010101

Title: Effects of n-tritriacontane-16,18-dione, curcumin, chlorphyllin, dihydroguaiaretic acid, tannic acid and phytic acid on the initiation stage in a rat multi-organ carcinogenesis model.

Journal: Cancer letters 19970226

Title: Decreased connexin32 and a characteristic enzyme phenotype in clofibrate-induced preneoplastic lesions not shared with spontaneously occurring lesions in the rat liver.

Journal: Carcinogenesis 19961101

Title: Absence of ras family point mutations at codons 12, 13 and 61 in N-ethyl-N-hydroxyethylnitrosamine- or N-nitrosomorpholine-induced renal cell tumors in rats.

Journal: Japanese journal of cancer research : Gann 19920901

Title: Modifying effects of various chemicals on tumor development in a rat wide-spectrum organ carcinogenesis model.

Journal: Japanese journal of cancer research : Gann 19920801

Title: Modifying effects of the naturally occurring antioxidants gamma-oryzanol, phytic acid, tannic acid and n-tritriacontane-16, 18-dione in a rat wide-spectrum organ carcinogenesis model.

Journal: Carcinogenesis 19911001

Title: Synergistic effects of low-dose hepatocarcinogens in induction of glutathione S-transferase P-positive foci in the rat liver.

Journal: Japanese journal of cancer research : Gann 19891001

Title: Changes in gap junction protein (connexin 32) gene expression during rat liver carcinogenesis.

Journal: Journal of cellular biochemistry 19891001

Title: Reciprocal modifying effects of isomeric forms of aminophenol on induction of neoplastic lesions in rat liver and kidney initiated by N-ethyl-N-hydroxyethylnitrosamine.

Journal: Carcinogenesis 19870901

Title: Inhibition of neoplastic development in rat liver, kidney, oesophagus and forestomach by 4,4'-diaminodiphenylmethane administration.

Journal: Carcinogenesis 19870501

Title: Modifying effects of butylated hydroxyanisole, ethoxyquin and acetaminophen on induction of neoplastic lesions in rat liver and kidney initiated by N-ethyl-N-hydroxyethylnitrosamine.

Journal: Carcinogenesis 19840401

Title: Modification of chemical carcinogenesis by antioxidants.

Journal: Princess Takamatsu symposia 19830101

Title: Inhibitory effect of 4,4'-diaminodiphenylmethane on liver, kidney and bladder carcinogenesis in rats ingesting N-ethyl-N-hydroxyethylnitrosamine or N-butyl-N-(4-hydroxybutyl) nitros-amine.

Journal: Carcinogenesis 19810101

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