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Journal: Cellular signalling 20121101
Title: Melittin has an inhibitory effect on TNF-α-induced migration of human aortic smooth muscle cells by blocking the MMP-9 expression.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20121101
Title: Effects of lipoic acid on lipolysis in 3T3-L1 adipocytes.
Journal: Journal of lipid research 20121101
Title: Opposed arsenite-mediated regulation of p53-survivin is involved in neoplastic transformation, DNA damage, or apoptosis in human keratinocytes.
Journal: Toxicology 20121028
Title: Diallyl trisulfide-induced prostate cancer cell death is associated with Akt/PKB dephosphorylation mediated by P-p66shc.
Journal: European journal of nutrition 20121001
Title: Distinct functions of JNK and c-Jun in oxidant-induced hepatocyte death.
Journal: Journal of cellular biochemistry 20121001
Title: JNK-dependent Stat3 phosphorylation contributes to Akt activation in response to arsenic exposure.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20121001
Title: Protective role of quercetin against lead-induced inflammatory response in rat kidney through the ROS-mediated MAPKs and NF-κB pathway.
Journal: Biochimica et biophysica acta 20121001
Title: Mitogen-activated protein kinases-dependent induction of hepatocyte growth factor production in human dermal fibroblasts by the antibiotic polymyxin B.
Journal: Cytokine 20121001
Title: Transcriptional and translational regulation of COX-2 expression by cadmium in C6 glioma cells.
Journal: International journal of molecular medicine 20121001
Title: Naringin attenuates EGF-induced MUC5AC secretion in A549 cells by suppressing the cooperative activities of MAPKs-AP-1 and IKKs-IκB-NF-κB signaling pathways.
Journal: European journal of pharmacology 20120905
Title: Protective role of metabolism by intestinal microflora in butyl paraben-induced toxicity in HepG2 cell cultures.
Journal: Toxicology letters 20120903
Title: Preliminary evidence for the dedifferentiation of RAW 264.7 cells into mesenchymal progenitor-like cells by a purine analog.
Journal: Tissue engineering. Part A 20120901
Title: Activation of macrophages by polysaccharide isolated from Paecilomyces cicadae through toll-like receptor 4.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20120901
Title: Sargachromanol G regulates the expression of osteoclastogenic factors in human osteoblast-like MG-63 cells.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20120901
Title: The p38 MAPK-MK2 axis regulates E2F1 and FOXM1 expression after epirubicin treatment.
Journal: Molecular cancer research : MCR 20120901
Title: Pimaric acid from Aralia cordata has an inhibitory effect on TNF-α-induced MMP-9 production and HASMC migration via down-regulated NF-κB and AP-1.
Journal: Chemico-biological interactions 20120830
Title: PAK1-dependent MAPK pathway activation is required for colorectal cancer cell proliferation.
Journal: Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 20120801
Title: Inhibitory effect of Styrax Japonica Siebold et al. Zuccarini glycoprotein (38 kDa) on interleukin-1β and induction proteins in chromium(VI)-treated BNL CL.2 cells.
Journal: Molecular and cellular biochemistry 20120801
Title: Tumor necrosis factor alpha stimulates cathepsin K and V activity via juxtacrine monocyte-endothelial cell signaling and JNK activation.
Journal: Molecular and cellular biochemistry 20120801
Title: Suppression of adhesion molecule expression by phenanthrene-containing extract of bulbils of Chinese Yam in vascular smooth muscle cells through inhibition of MAPK, Akt and NF-κB.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20120801
Title: Repression of transcription of presenilin-1 inhibits γ-secretase independent ER Ca²⁺ leak that is impaired by FAD mutations.
Journal: Journal of neurochemistry 20120801
Title: Inhibition of c-Jun N-terminal kinase prevents blood-brain barrier disruption and normalizes the expression of tight junction proteins clautin-5 and ZO-1 in a rat model of subarachnoid hemorrhage.
Journal: Acta neurochirurgica 20120801
Title: cAMP-dependent proteolysis of GATA-6 is linked to JNK-signaling pathway.
Journal: Biochemical and biophysical research communications 20120713
Title: Prodigiosin-induced cytotoxicity involves RAD51 down-regulation through the JNK and p38 MAPK pathways in human breast carcinoma cell lines.
Journal: Toxicology letters 20120707
Title: Inhibition of adrenergic human prostate smooth muscle contraction by the inhibitors of c-Jun N-terminal kinase, SP600125 and BI-78D3.
Journal: British journal of pharmacology 20120701
Title: Monocyte chemoattractant protein-1 mediates angiotensin II-induced vascular smooth muscle cell proliferation via SAPK/JNK and ERK1/2.
Journal: Molecular and cellular biochemistry 20120701
Title: The effects of ginsenoside Rb1 on JNK in oxidative injury in cardiomyocytes.
Journal: Archives of pharmacal research 20120701
Title: Evaluation of sirtuin role in neuroprotection of retinal ganglion cells in hypoxia.
Journal: Investigative ophthalmology & visual science 20120628
Title: Delayed inhibition of c-Jun N-terminal kinase worsens outcomes after focal cerebral ischemia.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20120613
Title: Sphingosine-1-phosphate is a mediator of TNF-α action on the Na+/K+ ATPase in HepG2 cells.
Journal: Journal of cellular biochemistry 20120601
Title: Cross-talk between receptor tyrosine kinase and tumor necrosis factor-α signaling networks regulates apoptosis but not proliferation.
Journal: Molecular & cellular proteomics : MCP 20120601
Title: Involvement of intracellular oxidative stress-sensitive pathway in phloxine B-induced photocytotoxicity in human T lymphocytic leukemia cells.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20120601
Title: Arsenic modulates heme oxygenase-1, interleukin-6, and vascular endothelial growth factor expression in endothelial cells: roles of ROS, NF-κB, and MAPK pathways.
Journal: Archives of toxicology 20120601
Title: Tumor necrosis factor-α and interleukin-1β expression pathway induced by Streptococcus mutans in macrophage cell line RAW 264.7.
Journal: Molecular oral microbiology 20120601
Title: [The protective effects of inhibition of c-Jun N-terminal kinase signal pathway on the intestinal barrier in rats with endotoxemia].
Journal: Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue 20120601
Title: Loss of T regulatory cell suppression following signaling through glucocorticoid-induced tumor necrosis receptor (GITR) is dependent on c-Jun N-terminal kinase activation.
Journal: The Journal of biological chemistry 20120518
Title: Arecoline-induced death of human leukemia K562 cells is associated with surface up-modulation of TNFR2.
Journal: Journal of cellular physiology 20120501
Title: Brain-derived neurotrophic factor increases expression of MnSOD in human circulating angiogenic cells.
Journal: Microvascular research 20120501
Title: Acetic acid- and phenyl-p-benzoquinone-induced overt pain-like behavior depends on spinal activation of MAP kinases, PI(3)K and microglia in mice.
Journal: Pharmacology, biochemistry, and behavior 20120501
Title: Intraperitoneal injection of JNK-specific inhibitor SP600125 inhibits the expression of presenilin-1 and Notch signaling in mouse brain without induction of apoptosis.
Journal: Brain research 20120411
Title: Regulation of cigarette smoke-mediated mucin expression by hypoxia-inducible factor-1α via epidermal growth factor receptor-mediated signaling pathways.
Journal: Journal of applied toxicology : JAT 20120401
Title: Enhanced phosphorylation of MAPKs by NE promotes TNF-α production by macrophage through α adrenergic receptor.
Journal: Inflammation 20120401
Title: IL-33 is induced by amyloid-β stimulation and regulates inflammatory cytokine production in retinal pigment epithelium cells.
Journal: Inflammation 20120401
Title: Ethanol extract of Prunella vulgaris var. lilacina inhibits HMGB1 release by induction of heme oxygenase-1 in LPS-activated RAW 264.7 cells and CLP-induced septic mice.
Journal: Phytotherapy research : PTR 20120401
Title: Effects of c-Jun N-terminal kinase signaling pathway on severe acute pancreatitis-associated lung injury.
Journal: Pancreas 20120401
Title: High glucose induces renal mesangial cell proliferation and fibronectin expression through JNK/NF-κB/NADPH oxidase/ROS pathway, which is inhibited by resveratrol.
Journal: The international journal of biochemistry & cell biology 20120401
Title: Daunorubicin induces cell death via activation of apoptotic signalling pathway and inactivation of survival pathway in muscle-derived stem cells.
Journal: Cell biology and toxicology 20120401
Title: Dynamics and regulation of lipid droplet formation in lipopolysaccharide (LPS)-stimulated microglia.
Journal: Biochimica et biophysica acta 20120401
Title: Cyclooxygenase-2 expression is up-regulated by 2-aminobiphenyl in a ROS and MAPK-dependent signaling pathway in a bladder cancer cell line.
Journal: Chemical research in toxicology 20120319
Title: Ginsenoside Rh1 suppresses matrix metalloproteinase-1 expression through inhibition of activator protein-1 and mitogen-activated protein kinase signaling pathway in human hepatocellular carcinoma cells.
Journal: European journal of pharmacology 20120315
Title: Inhibition of JNK/dFOXO pathway and caspases rescues neurological impairments in Drosophila Alzheimer's disease model.
Journal: Biochemical and biophysical research communications 20120302
Title: Involvement of calcium-sensing receptor in oxLDL-induced MMP-2 production in vascular smooth muscle cells via PI3K/Akt pathway.
Journal: Molecular and cellular biochemistry 20120301
Title: Zinc oxide nanoparticles-induced intercellular adhesion molecule 1 expression requires Rac1/Cdc42, mixed lineage kinase 3, and c-Jun N-terminal kinase activation in endothelial cells.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20120301
Title: Inhibition of glycogen synthase kinase-3 activity triggers an apoptotic response in pancreatic cancer cells through JNK-dependent mechanisms.
Journal: Carcinogenesis 20120301
Title: Nicotine stimulates urokinase-type plasminogen activator receptor expression and cell invasiveness through mitogen-activated protein kinase and reactive oxygen species signaling in ECV304 endothelial cells.
Journal: Toxicology and applied pharmacology 20120301
Title: P53 activation plays a crucial role in silibinin induced ROS generation via PUMA and JNK.
Journal: Free radical research 20120301
Title: Fructose-1,6-bisphosphate attenuates induction of nitric oxide synthase in microglia stimulated with lipopolysaccharide.
Journal: Life sciences 20120227
Title: Involvement of oxidative stress-induced ERK/JNK activation in the Cu(2+)/pyrrolidine dithiocarbamate complex-triggered mitochondria-regulated apoptosis in pancreatic β-cells.
Journal: Toxicology letters 20120205
Title: Effect of donor JNK signal transduction inhibition on transplant outcome in brain dead rat model.
Journal: Inflammation 20120201
Title: Quercetin supplementation suppresses the secretion of pro-inflammatory cytokines in the lungs of Mongolian gerbils and in A549 cells exposed to benzo[a]pyrene alone or in combination with β-carotene: in vivo and ex vivo studies.
Journal: The Journal of nutritional biochemistry 20120201
Title: Genistein inhibit cytokines or growth factor-induced proliferation and transformation phenotype in fibroblast-like synoviocytes of rheumatoid arthritis.
Journal: Inflammation 20120201
Title: Ischemia-induced stimulation of cerebral microvascular endothelial cell Na-K-Cl cotransport involves p38 and JNK MAP kinases.
Journal: American journal of physiology. Cell physiology 20120201
Title: Heme oxygenase-1 mediates the protective role of quercetin against ethanol-induced rat hepatocytes oxidative damage.
Journal: Toxicology in vitro : an international journal published in association with BIBRA 20120201
Title: Novel role of c-jun N-terminal kinase in regulating the initiation of cap-dependent translation.
Journal: International journal of oncology 20120201
Title: Exploring the function of the JNK (c-Jun N-terminal kinase) signalling pathway in physiological and pathological processes to design novel therapeutic strategies.
Journal: Biochemical Society transactions 20120201
Title: SNP-induced apoptosis may be mediated with caspase inhibitor by JNK signaling pathways in rabbit articular chondrocytes.
Journal: The Journal of toxicological sciences 20120201
Title: [Effect of expression of c-jun N-terminal kinase on neuron autophagy following diffuse brain injury in rats].
Journal: Zhonghua wai ke za zhi [Chinese journal of surgery] 20120201
Title: Smad7 acts as a negative regulator of the epidermal growth factor (EGF) signaling pathway in breast cancer cells.
Journal: Cancer letters 20120128
Title: Prostaglandin E2 enhances interleukin-8 production via EP4 receptor in human pulmonary microvascular endothelial cells.
Journal: American journal of physiology. Lung cellular and molecular physiology 20120115
Title: A pharmacologically-based array to identify targets of cyclosporine A-induced toxicity in cultured renal proximal tubule cells.
Journal: Toxicology and applied pharmacology 20120115
Title: c-Jun N-terminal kinase 2 phosphorylates endothelial nitric oxide synthase at serine 116 and regulates nitric oxide production.
Journal: Biochemical and biophysical research communications 20120106
Title: Human foetal intestinal fibroblasts are hyper-responsive to lipopolysaccharide stimulation.
Journal: Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20120101
Title: Involvement of JNK and NF-κB pathways in lipopolysaccharide (LPS)-induced BAG3 expression in human monocytic cells.
Journal: Experimental cell research 20120101
Title: The dysregulation of the monocyte/macrophage effector function induced by isopropanol is mediated by the defective activation of distinct members of the AP-1 family of transcription factors.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20120101
Title: Function of MAPK and downstream transcription factors in monomer-induced apoptosis.
Journal: Biomaterials 20120101
Title: The saturated fatty acid palmitate induces human monocytic cell toxicity toward neuronal cells: exploring a possible link between obesity-related metabolic impairments and neuroinflammation.
Journal: Journal of Alzheimer's disease : JAD 20120101
Title: Mutual regulation of growth hormone and bone morphogenetic protein system in steroidogenesis by rat granulosa cells.
Journal: Endocrinology 20120101
Title: SP600125 inhibits Orthopoxviruses replication in a JNK1/2 -independent manner: Implication as a potential antipoxviral.
Journal: Antiviral research 20120101
Title: GW8510 increases insulin expression in pancreatic alpha cells through activation of p53 transcriptional activity.
Journal: PloS one 20120101
Title: miR-16 targets transcriptional corepressor SMRT and modulates NF-kappaB-regulated transactivation of interleukin-8 gene.
Journal: PloS one 20120101
Title: Cyclin D1 induction preceding neuronal death via the excitotoxic NMDA pathway involves selective stimulation of extrasynaptic NMDA receptors and JNK pathway.
Journal: Neuro-degenerative diseases 20120101
Title: Activation of JNK signaling mediates connective tissue growth factor expression and scar formation in corneal wound healing.
Journal: PloS one 20120101
Title: Effects of dihydropyridine calcium channel blockers on oxidized low-density lipoprotein induced proliferation and oxidative stress of vascular smooth muscle cells.
Journal: BMC research notes 20120101
Title: High-mobility group box 1 protein is implicated in advanced glycation end products-induced vascular endothelial growth factor A production in the rat retinal ganglion cell line RGC-5.
Journal: Molecular vision 20120101
Title: MEKK1-MKK4-JNK-AP1 pathway negatively regulates Rgs4 expression in colonic smooth muscle cells.
Journal: PloS one 20120101
Title: Curcumin enhances cytotoxic effects of bortezomib in human multiple myeloma H929 cells: potential roles of NF-κB/JNK.
Journal: International journal of molecular sciences 20120101
Title: Neuregulin promotes incomplete autophagy of prostate cancer cells that is independent of mTOR pathway inhibition.
Journal: PloS one 20120101
Title: Camel milk triggers apoptotic signaling pathways in human hepatoma HepG2 and breast cancer MCF7 cell lines through transcriptional mechanism.
Journal: Journal of biomedicine & biotechnology 20120101
Title: Interleukin-1 induction of aggrecanase gene expression in human articular chondrocytes is mediated by mitogen-activated protein kinases.
Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20120101
Title: Apoptotic effects of satratoxin H is mediated through DNA double-stranded break in PC12 cells.
Journal: The Journal of toxicological sciences 20120101
Title: Increased JNK1 signaling pathway is responsible for ABCG2-mediated multidrug resistance in human colon cancer.
Journal: PloS one 20120101
Title: [Effects of several inhibitors of intracellular signaling on production of cytokines and signal proteins in RAW 264.7 cells cultivated with low dose ammonium].
Journal: Biofizika 20120101
Title: Inhibition of TDP-43 accumulation by bis(thiosemicarbazonato)-copper complexes.
Journal: PloS one 20120101
Title: Mda-9/syntenin promotes human brain glioma migration through focal adhesion kinase (FAK)-JNK and FAK-AKT signaling.
Journal: Asian Pacific journal of cancer prevention : APJCP 20120101
Title: The apoptotic volume decrease is an upstream event of MAP kinase activation during Staurosporine-induced apoptosis in HeLa cells.
Journal: International journal of molecular sciences 20120101
Title: Stressor-like effects of c-Jun N-terminal kinase (JNK) inhibition.
Journal: PloS one 20120101
Title: Calcium entry mediates hyperglycemia-induced apoptosis through Ca(2+)/calmodulin-dependent kinase II in retinal capillary endothelial cells.
Journal: Molecular vision 20120101
Title: Green tea polyphenols induce p53-dependent and p53-independent apoptosis in prostate cancer cells through two distinct mechanisms.
Journal: PloS one 20120101
Title: Disulfiram/copper complex activated JNK/c-jun pathway and sensitized cytotoxicity of doxorubicin in doxorubicin resistant leukemia HL60 cells.
Journal: Blood cells, molecules & diseases 20111215
Title: Flavonoids inhibit high glucose-induced up-regulation of ICAM-1 via the p38 MAPK pathway in human vein endothelial cells.
Journal: Biochemical and biophysical research communications 20111202
Title: Ablation of c-FLIP in hepatocytes enhances death-receptor mediated apoptosis and toxic liver injury in vivo.
Journal: Journal of hepatology 20111201
Title: Novel participation of transglutaminase-2 through c-Jun N-terminal kinase activation in sphingosylphosphorylcholine-induced keratin reorganization of PANC-1 cells.
Journal: Biochimica et biophysica acta 20111201
Title: MAPK phosphatase-1 contributes to trichostatin A inhibition of cyclooxygenase-2 expression in human umbilical vascular endothelial cells exposed to lipopolysaccharide.
Journal: Biochimica et biophysica acta 20111201
Title: CaMKII is involved in cadmium activation of MAPK and mTOR pathways leading to neuronal cell death.
Journal: Journal of neurochemistry 20111201
Title: MAPK and AP-1 proteins are increased in term pre-labour fetal membranes overlying the cervix: regulation of enzymes involved in the degradation of fetal membranes.
Journal: Placenta 20111201
Title: JNK inhibitors increase osteogenesis in Nf1-deficient cells.
Journal: Bone 20111201
Title: Novel stably transfected gene reporter human hepatoma cell line for assessment of aryl hydrocarbon receptor transcriptional activity: construction and characterization.
Journal: Environmental science & technology 20111201
Title: Porphyromonas endodontalis lipopolysaccharides induce RANKL by mouse osteoblast in a way different from that of Escherichia coli lipopolysaccharide.
Journal: Journal of endodontics 20111201
Title: Thymus peptides regulate activity of RAW 264.7 macrophage cells: inhibitory analysis and a role of signal cascades.
Journal: Expert opinion on therapeutic targets 20111201
Title: Activation of the c-Jun N-terminal kinase/activating transcription factor 3 (ATF3) pathway characterizes effective arylated diazeniumdiolate-based nitric oxide-releasing anticancer prodrugs.
Journal: Journal of medicinal chemistry 20111124
Title: Ellipticine induces apoptosis in human endometrial cancer cells: the potential involvement of reactive oxygen species and mitogen-activated protein kinases.
Journal: Toxicology 20111118
Title: Nickel(II) induced JNK activation-regulated mitochondria-dependent apoptotic pathway leading to cultured rat pancreatic β-cell death.
Journal: Toxicology 20111118
Title: Antimetastatic effect and mechanism of ovatodiolide in MDA-MB-231 human breast cancer cells.
Journal: Chemico-biological interactions 20111115
Title: Lung injury caused by high tidal volume mechanical ventilation and hyperoxia is dependent on oxidant-mediated c-Jun NH2-terminal kinase activation.
Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20111101
Title: c-Jun N-terminal kinase induces axonal degeneration and limits motor recovery after spinal cord injury in mice.
Journal: Neuroscience research 20111101
Title: Thymosin β4 activates integrin-linked kinase and decreases endothelial progenitor cells apoptosis under serum deprivation.
Journal: Journal of cellular physiology 20111101
Title: Sodium dl-α-tocopheryl-6-O-phosphate inhibits PGE₂ production in keratinocytes induced by UVB, IL-1β and peroxidants.
Journal: Bioorganic & medicinal chemistry 20111101
Title: The Ebolavirus VP24 protein blocks phosphorylation of p38 mitogen-activated protein kinase.
Journal: The Journal of infectious diseases 20111101
Title: FGF-2- and TGF-β1-induced downregulation of lumican and keratocan in activated corneal keratocytes by JNK signaling pathway.
Journal: Investigative ophthalmology & visual science 20111101
Title: Comprehensive assay of kinase catalytic activity reveals features of kinase inhibitor selectivity.
Journal: Nature biotechnology 20111101
Title: Inhibition of c-Jun-N-terminal kinase increases cardiac peroxisome proliferator-activated receptor alpha expression and fatty acid oxidation and prevents lipopolysaccharide-induced heart dysfunction.
Journal: The Journal of biological chemistry 20111021
Title: Levodopa activates apoptosis signaling kinase 1 (ASK1) and promotes apoptosis in a neuronal model: implications for the treatment of Parkinson's disease.
Journal: Chemical research in toxicology 20111017
Title: Up-regulation of cyclin D1 by JNK1/c-Jun is involved in tumorigenesis of human embryo lung fibroblast cells induced by a low concentration of arsenite.
Journal: Toxicology letters 20111010
Title: Carmustine induces ERK- and JNK-dependent cell death of neuronally-differentiated PC12 cells via generation of reactive oxygen species.
Journal: Toxicology in vitro : an international journal published in association with BIBRA 20111001
Title: Apolipoprotein D mediates autocrine protection of astrocytes and controls their reactivity level, contributing to the functional maintenance of paraquat-challenged dopaminergic systems.
Journal: Glia 20111001
Title: Parathyroid hormone and the regulation of cell cycle in colon adenocarcinoma cells.
Journal: Biochimica et biophysica acta 20111001
Title: JNK inhibition by SP600125 attenuates trans-10, cis-12 conjugated linoleic acid-mediated regulation of inflammatory and lipogenic gene expression.
Journal: Lipids 20111001
Title: Fluvastatin enhances sorafenib cytotoxicity in melanoma cells via modulation of AKT and JNK signaling pathways.
Journal: Anticancer research 20111001
Title: Design and characterization of a potent and selective dual ATP- and substrate-competitive subnanomolar bidentate c-Jun N-terminal kinase (JNK) inhibitor.
Journal: Journal of medicinal chemistry 20110922
Title: Activation of non-canonical Wnt/JNK pathway by Wnt3a is associated with differentiation fate determination of human bone marrow stromal (mesenchymal) stem cells.
Journal: Biochemical and biophysical research communications 20110916
Title: Angiotensin II type 1 receptor signalling regulates microRNA differentially in cardiac fibroblasts and myocytes.
Journal: British journal of pharmacology 20110901
Title: Arsenic trioxide induces autophagy and apoptosis in human glioma cells in vitro and in vivo through downregulation of survivin.
Journal: Journal of molecular medicine (Berlin, Germany) 20110901
Title: tPA contributes to impaired NMDA cerebrovasodilation after traumatic brain injury through activation of JNK MAPK.
Journal: Neurological research 20110901
Title: Arsenic increases lipopolysaccharide-dependent expression of interleukin-8 gene by stimulating a redox-sensitive pathway that strengthens p38-kinase activation.
Journal: Molecular immunology 20110901
Title: Inducible nitric-oxide synthase and nitric oxide donor decrease insulin receptor substrate-2 protein expression by promoting proteasome-dependent degradation in pancreatic beta-cells: involvement of glycogen synthase kinase-3beta.
Journal: The Journal of biological chemistry 20110819
Title: Hepatocyte growth factor induces a proangiogenic phenotype and mobilizes endothelial progenitor cells by activating Nox2.
Journal: Antioxidants & redox signaling 20110815
Title: Vitamin K3-2,3-epoxide induction of apoptosis with activation of ROS-dependent ERK and JNK protein phosphorylation in human glioma cells.
Journal: Chemico-biological interactions 20110815
Title: Vinblastine sensitizes leukemia cells to cyclin-dependent kinase inhibitors, inducing acute cell cycle phase-independent apoptosis.
Journal: Cancer biology & therapy 20110815
Title: MAPKs ERK and p38, but not JNK phosphorylation, modulate IL-6 and TNF-α secretion following OK-432 in vitro stimulation of purified human monocytes.
Journal: Scandinavian journal of immunology 20110801
Title: Increased JNK1 activity contributes to the upregulation of ApoD in the apocrine secretory gland cells from axillary osmidrosis.
Journal: Molecular and cellular biochemistry 20110801
Title: Critical role of c-Jun N-terminal kinase in regulating bFGF-induced angiogenesis in vitro.
Journal: Journal of biochemistry 20110801
Title: A novel 3-dimensional culture system uncovers growth stimulatory actions by TGFβ in pancreatic cancer cells.
Journal: Cancer biology & therapy 20110801
Title: P66Shc mediated ferritin degradation--a novel mechanism of ROS formation.
Journal: Free radical biology & medicine 20110801
Title: Effects of downregulation of aquaporin1 by peptidoglycan and lipopolysaccharide via MAPK pathways in MeT-5A cells.
Journal: Lung 20110801
Title: The ETS family transcription factor ELK-1 regulates induction of the cell cycle-regulatory gene p21(Waf1/Cip1) and the BAX gene in sodium arsenite-exposed human keratinocyte HaCaT cells.
Journal: The Journal of biological chemistry 20110729
Title: Increased level of apoptosis in rat brains and SH-SY5Y cells exposed to excessive fluoride--a mechanism connected with activating JNK phosphorylation.
Journal: Toxicology letters 20110728
Title: SIRT1 deficiency downregulates PTEN/JNK/FOXO1 pathway to block reactive oxygen species-induced apoptosis in mouse embryonic stem cells.
Journal: Stem cells and development 20110701
Title: 5-aminolevulinic acid induce apoptosis via NF-κB/JNK pathway in human oral cancer Ca9-22 cells.
Journal: Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 20110701
Title: Dermal fibroblasts influence the expression profile of 14-3-3 proteins in human keratinocytes.
Journal: Molecular and cellular biochemistry 20110701
Title: ERK is involved in EGF-mediated protection of tight junctions, but not adherens junctions, in acetaldehyde-treated Caco-2 cell monolayers.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20110701
Title: Protective effects of SP600125 on renal ischemia-reperfusion injury in rats.
Journal: The Journal of surgical research 20110701
Title: CXCL2 mediates lipopolysaccharide-induced osteoclastogenesis in RANKL-primed precursors.
Journal: Cytokine 20110701
Title: Brazilian propolis-derived components inhibit TNF-α-mediated downregulation of adiponectin expression via different mechanisms in 3T3-L1 adipocytes.
Journal: Biochimica et biophysica acta 20110701
Title: Identification of new inhibitors of protein kinase R guided by statistical modeling.
Journal: Bioorganic & medicinal chemistry letters 20110701
Title: CPEB1 modulates lipopolysaccharide-mediated iNOS induction in rat primary astrocytes.
Journal: Biochemical and biophysical research communications 20110617
Title: Phosphorylation of JDP2 on threonine-148 by the c-Jun N-terminal kinase targets it for proteosomal degradation.
Journal: The Biochemical journal 20110615
Title: Toll-like receptor 2-mediated sequential activation of MyD88 and MAPKs contributes to lipopolysaccharide-induced sp-a gene expression in human alveolar epithelial cells.
Journal: Immunobiology 20110601
Title: Roles of mitogen-activated protein kinases in the modulation of endothelial cell function following thermal injury.
Journal: Shock (Augusta, Ga.) 20110601
Title: Pro-inflammatory cytokines intensify the activation of NO/NOS, JNK1/2 and caspase cascades in immature neurons exposed to elevated levels of unconjugated bilirubin.
Journal: Experimental neurology 20110601
Title: The signalling axis mediating neuronal apoptosis in response to [Pt(O,O'-acac)(γ-acac)(DMS)].
Journal: Biochemical pharmacology 20110601
Title: Hyperglycemia induces apoptosis of pancreatic islet endothelial cells via reactive nitrogen species-mediated Jun N-terminal kinase activation.
Journal: Biochimica et biophysica acta 20110601
Title: Regulation of Hsp27 and Hsp70 expression in human and mouse skin construct models by caveolae following exposure to the model sulfur mustard vesicant, 2-chloroethyl ethyl sulfide.
Journal: Toxicology and applied pharmacology 20110601
Title: Imatinib mesylate induction of ROS-dependent apoptosis in melanoma B16F0 cells.
Journal: Journal of dermatological science 20110601
Title: Tissue factor pathway inhibitor 2 is induced by thrombin in human macrophages.
Journal: Biochimica et biophysica acta 20110601
Title: Suppression of phorbol-12-myristate-13-acetate-induced tumor cell invasion by piperine via the inhibition of PKCα/ERK1/2-dependent matrix metalloproteinase-9 expression.
Journal: Toxicology letters 20110530
Title: Targeting the JNK signaling pathway potentiates the antiproliferative efficacy of rapamycin in LS174T colon cancer cells.
Journal: The Journal of surgical research 20110515
Title: Virtual screening and further development of novel ALK inhibitors.
Journal: Bioorganic & medicinal chemistry 20110515
Title: Activation of the JNK pathway by nanosecond pulsed electric fields.
Journal: Biochemical and biophysical research communications 20110513
Title: Cinnamaldehyde enhances Nrf2 nuclear translocation to upregulate phase II detoxifying enzyme expression in HepG2 cells.
Journal: Journal of agricultural and food chemistry 20110511
Title: Role of JNK/ATF-2 pathway in inhibition of thrombospondin-1 (TSP-1) expression and apoptosis mediated by doxorubicin and camptothecin in FTC-133 cells.
Journal: Biochimica et biophysica acta 20110501
Title: Regulation of JNK activity in the apoptotic response of intestinal epithelial cells.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20110501
Title: Lipopolysaccharide signaling without a nucleus: kinase cascades stimulate platelet shedding of proinflammatory IL-1β-rich microparticles.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20110501
Title: c-Jun NH₂-terminal kinase contributes to dexmedetomidine-induced contraction in isolated rat aortic smooth muscle.
Journal: Yonsei medical journal 20110501
Title: Interference of the apoptotic signaling pathway in RGC stress response by SP600125 in moderate ocular hypertensive rats.
Journal: The Chinese journal of physiology 20110430
Title: Noncanonical TGFβ signaling contributes to aortic aneurysm progression in Marfan syndrome mice.
Journal: Science (New York, N.Y.) 20110415
Title: 5-Hydroxytryptamine induces cyclooxygenase-2 in rat vascular smooth muscle cells: Mechanisms involving Src, PKC and MAPK activation [corrected].
Journal: European journal of pharmacology 20110410
Title: p,p'-Dichlorodiphenoxydichloroethylene induced apoptosis of Sertoli cells through oxidative stress-mediated p38 MAPK and mitochondrial pathway.
Journal: Toxicology letters 20110410
Title: Helicobacter pylori VacA reduces the cellular expression of STAT3 and pro-survival Bcl-2 family proteins, Bcl-2 and Bcl-XL, leading to apoptosis in gastric epithelial cells.
Journal: Digestive diseases and sciences 20110401
Title: Fluid shear stress induces renal epithelial gene expression through polycystin-2-dependent trafficking of extracellular regulated kinase.
Journal: Nephron. Physiology 20110401
Title: Lithospermic acid B protects β-cells from cytokine-induced apoptosis by alleviating apoptotic pathways and activating anti-apoptotic pathways of Nrf2-HO-1 and Sirt1.
Journal: Toxicology and applied pharmacology 20110401
Title: Insulin-induced oxidative stress up-regulates heme oxygenase-1 via diverse signaling cascades in the C2 skeletal myoblast cell line.
Journal: Endocrinology 20110401
Title: Role of c-Jun N-terminal kinase activation in blastema formation during planarian regeneration.
Journal: Development, growth & differentiation 20110401
Title: Pro-survival effects of JNK and p38 MAPK pathways in LPS-induced activation of BV-2 cells.
Journal: Biochemical and biophysical research communications 20110318
Title: Cadmium induces phosphorylation and stabilization of c-Fos in HK-2 renal proximal tubular cells.
Journal: Toxicology and applied pharmacology 20110315
Title: Involvement of heme oxygenase-1 induction via Nrf2/ARE activation in protection against H2O2-induced PC12 cell death by a metabolite of sesamin contained in sesame seeds.
Journal: Bioorganic & medicinal chemistry 20110315
Title: Apoptosis induced by a new flavonoid in human hepatoma HepG2 cells involves reactive oxygen species-mediated mitochondrial dysfunction and MAPK activation.
Journal: European journal of pharmacology 20110311
Title: Stimulation of pro-inflammatory responses by mebendazole in human monocytic THP-1 cells through an ERK signaling pathway.
Journal: Archives of toxicology 20110301
Title: Preantral follicle growth is regulated by c-Jun-N-terminal kinase (JNK) pathway.
Journal: Reproductive sciences (Thousand Oaks, Calif.) 20110301
Title: Inhibition of JNK phosphorylation reverses memory deficit induced by β-amyloid (1-42) associated with decrease of apoptotic factors.
Journal: Behavioural brain research 20110301
Title: Upregulation of RhoB via c-Jun N-terminal kinase signaling induces apoptosis of the human gastric carcinoma NUGC-3 cells treated with NSC12618.
Journal: Carcinogenesis 20110301
Title: Androgen receptor-mediated regulation of the anti-atherogenic enzyme CYP27A1 involves the JNK/c-jun pathway.
Journal: Archives of biochemistry and biophysics 20110215
Title: JNK regulates binding of alpha-catenin to adherens junctions and cell-cell adhesion.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20110201
Title: Modulation of ROS/MAPK signaling pathways by okadaic acid leads to cell death via, mitochondrial mediated caspase-dependent mechanism.
Journal: Apoptosis : an international journal on programmed cell death 20110201
Title: Quercetin induces FasL-related apoptosis, in part, through promotion of histone H3 acetylation in human leukemia HL-60 cells.
Journal: Oncology reports 20110201
Title: Targeting transcription through inhibition of TBP.
Journal: Oncotarget 20110201
Title: α-TEA cooperates with MEK or mTOR inhibitors to induce apoptosis via targeting IRS/PI3K pathways.
Journal: British journal of cancer 20110104
Title: Mitogen-activated protein kinase inhibitors improve heart function and prevent fibrosis in cardiomyopathy caused by mutation in lamin A/C gene.
Journal: Circulation 20110104
Title: Fluid shear stress-induced JNK activity leads to actin remodeling for cell alignment.
Journal: Journal of cellular physiology 20110101
Title: Gefitinib-induced epidermal growth factor receptor-independent keratinocyte apoptosis is mediated by the JNK activation pathway.
Journal: The British journal of dermatology 20110101
Title: Poly(I:C) reduces expression of JAM-A and induces secretion of IL-8 and TNF-α via distinct NF-κB pathways in human nasal epithelial cells.
Journal: Toxicology and applied pharmacology 20110101
Title: Critical role of the JNK-p53-GADD45α apoptotic cascade in mediating oxidative cytotoxicity in hippocampal neurons.
Journal: British journal of pharmacology 20110101
Title: Enteral arginine modulates inhibition of AP-1/c-Jun by SP600125 in the postischemic gut.
Journal: Molecular and cellular biochemistry 20110101
Title: Epimorphin protects hepatocytes from oxidative stress by inhibiting mitochondrial injury.
Journal: Journal of gastroenterology and hepatology 20110101
Title: The sequential combination of a JNK inhibitor and simvastatin protects porcine islets from peritransplant apoptosis and inflammation.
Journal: Cell transplantation 20110101
Title: SP600125 inhibits cap-dependent translation independently of the c-Jun N-terminal kinase pathway.
Journal: Cell structure and function 20110101
Title: [Effect of JNK pathway in apoptosis of PC12 cell by MPP+].
Journal: Wei sheng yan jiu = Journal of hygiene research 20110101
Title: Attenuated expression and function of the RECK tumor suppressor under hypoxic conditions is mediated by the MAPK signaling pathways.
Journal: Archives of pharmacal research 20110101
Title: Activation of NAG-1 via JNK signaling revealed an isochaihulactone-triggered cell death in human LNCaP prostate cancer cells.
Journal: BMC cancer 20110101
Title: Protective effect of a JNK inhibitor against retinal ganglion cell loss induced by acute moderate ocular hypertension.
Journal: Molecular vision 20110101
Title: Tumor necrosis factor-α enhances hyperbaric oxygen-induced visfatin expression via JNK pathway in human coronary arterial endothelial cells.
Journal: Journal of biomedical science 20110101
Title: Dual specificity phosphatase 1 regulates human inducible nitric oxide synthase expression by p38 MAP kinase.
Journal: Mediators of inflammation 20110101
Title: CP690,550 inhibits oncostatin M-induced JAK/STAT signaling pathway in rheumatoid synoviocytes.
Journal: Arthritis research & therapy 20110101
Title: Suppression of MMP-2 attenuates TNF-α induced NF-κB activation and leads to JNK mediated cell death in glioma.
Journal: PloS one 20110101
Title: Inhibition of c-Jun N-terminal kinase attenuates low shear stress-induced atherogenesis in apolipoprotein E-deficient mice.
Journal: Molecular medicine (Cambridge, Mass.) 20110101
Title: Vitamin K3 and vitamin C alone or in combination induced apoptosis in leukemia cells by a similar oxidative stress signalling mechanism.
Journal: Cancer cell international 20110101
Title: Midazolam suppresses interleukin-1β-induced interleukin-6 release from rat glial cells.
Journal: Journal of neuroinflammation 20110101
Title: Resveratrol inhibits Cdk5 activity through regulation of p35 expression.
Journal: Molecular pain 20110101
Title: Lipopolysaccharide-induced Notch signaling activation through JNK-dependent pathway regulates inflammatory response.
Journal: Journal of biomedical science 20110101
Title: Unfertilized Xenopus eggs die by Bad-dependent apoptosis under the control of Cdk1 and JNK.
Journal: PloS one 20110101
Title: Stretch-inducible expression of connective tissue growth factor (CTGF) in human osteoblasts-like cells is mediated by PI3K-JNK pathway.
Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20110101
Title: Coordinated regulation of ATF2 by miR-26b in γ-irradiated lung cancer cells.
Journal: PloS one 20110101
Title: c-Jun NH2-terminal kinase activation is essential for up-regulation of LC3 during ceramide-induced autophagy in human nasopharyngeal carcinoma cells.
Journal: Journal of translational medicine 20110101
Title: Versican G3 domain modulates breast cancer cell apoptosis: a mechanism for breast cancer cell response to chemotherapy and EGFR therapy.
Journal: PloS one 20110101
Title: Pyrrolidine dithiocarbamate (PDTC)/Cu complex induces lung epithelial cell apoptosis through mitochondria and ER-stress pathways.
Journal: Toxicology letters 20101215
Title: Cardiac-specific overexpression of catalase attenuates paraquat-induced myocardial geometric and contractile alteration: role of ER stress.
Journal: Free radical biology & medicine 20101215
Title: Endoplasmic reticulum stress-mediated apoptosis of EBV-transformed B cells by cross-linking of CD70 is dependent upon generation of reactive oxygen species and activation of p38 MAPK and JNK pathway.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20101215
Title: Targeting the mitotic checkpoint for cancer therapy with NMS-P715, an inhibitor of MPS1 kinase.
Journal: Cancer research 20101215
Title: p22phox-dependent NADPH oxidase activity is required for megakaryocytic differentiation.
Journal: Cell death and differentiation 20101201
Title: JNK-mediated transcriptional upregulation of RhoB is critical for apoptosis of HCT-116 colon cancer cells by a novel diarylsulfonylurea derivative.
Journal: Apoptosis : an international journal on programmed cell death 20101201
Title: Upregulation of contractile endothelin type B receptors by lipid-soluble cigarette smoking particles in rat cerebral arteries via activation of MAPK.
Journal: Toxicology and applied pharmacology 20101115
Title: Induction of DNA damage-inducible gene GADD45beta contributes to sorafenib-induced apoptosis in hepatocellular carcinoma cells.
Journal: Cancer research 20101115
Title: Resveratrol enhances NK cell cytotoxicity: possible role for aryl hydrocarbon receptor.
Journal: Journal of cellular physiology 20101101
Title: DJ-1, a cancer and Parkinson's disease associated protein, regulates autophagy through JNK pathway in cancer cells.
Journal: Cancer letters 20101101
Title: Icaritin induces apoptosis of HepG2 cells via the JNK1 signaling pathway independent of the estrogen receptor.
Journal: Planta medica 20101101
Title: The mechanism for the neuroprotective effect of melatonin against methamphetamine-induced autophagy.
Journal: Journal of pineal research 20101101
Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.
Journal: Bioorganic & medicinal chemistry letters 20101101
Title: The c-Jun N-terminal kinase inhibitor SP600125 is neuroprotective in amygdala kindled rats.
Journal: Brain research 20101021
Title: The role of cyclooxygenase-2-dependent signaling via cyclic AMP response element activation on aromatase up-regulation by o,p'-DDT in human breast cancer cells.
Journal: Toxicology letters 20101020
Title: Enantioselective cytotoxicity of isocarbophos is mediated by oxidative stress-induced JNK activation in human hepatocytes.
Journal: Toxicology 20101009
Title: 3-Caffeoyl, 4-dihydrocaffeoylquinic acid from Salicornia herbacea inhibits tumor cell invasion by regulating protein kinase C-delta-dependent matrix metalloproteinase-9 expression.
Journal: Toxicology letters 20101005
Title: SP600125, a competitive inhibitor of JNK attenuates streptozotocin induced neurocognitive deficit and oxidative stress in rats.
Journal: Pharmacology, biochemistry, and behavior 20101001
Title: MCP-1 production in temporomandibular joint inflammation.
Journal: Journal of dental research 20101001
Title: [Simvastatin suppress lipopolysaccharides induced upregulation of lipoprotein associated phospholipase A(2) expression in macrophages via inactivation of p38MAPK pathway].
Journal: Zhonghua xin xue guan bing za zhi 20101001
Title: The JNK inhibitor SP600125 enhances dihydroartemisinin-induced apoptosis by accelerating Bax translocation into mitochondria in human lung adenocarcinoma cells.
Journal: FEBS letters 20100924
Title: Induction of B-chronic lymphocytic leukemia cell apoptosis by arsenic trioxide involves suppression of the phosphoinositide 3-kinase/Akt survival pathway via c-jun-NH2 terminal kinase activation and PTEN upregulation.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20100901
Title: Lipid soluble smoke particles upregulate endothelin receptors in rat basilar artery.
Journal: Toxicology letters 20100901
Title: Negative modulation of invariant natural killer T cell responses to glycolipid antigens by p38 MAP kinase.
Journal: International immunopharmacology 20100901
Title: Down-regulation of MMP-2 through the p38 MAPK-NF-kappaB-dependent pathway by aloe-emodin leads to inhibition of nasopharyngeal carcinoma cell invasion.
Journal: Molecular carcinogenesis 20100901
Title: Notch1 expression predicts an unfavorable prognosis and serves as a therapeutic target of patients with neuroblastoma.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20100901
Title: Diallyl disulfide induces apoptosis in human leukemia HL-60 cells through activation of JNK mediated by reactive oxygen.
Journal: Die Pharmazie 20100901
Title: HDAC inhibitor, scriptaid, induces glioma cell apoptosis through JNK activation and inhibits telomerase activity.
Journal: Journal of cellular and molecular medicine 20100801
Title: Pyrogallol-induced As4.1 juxtaglomerular cell death is attenuated by MAPK inhibitors via preventing GSH depletion.
Journal: Archives of toxicology 20100801
Title: Impaired dephosphorylation renders G6PD-knockdown HepG2 cells more susceptible to H(2)O(2)-induced apoptosis.
Journal: Free radical biology & medicine 20100801
Title: JNK1 and JNK2 differently regulate IL-12 production in THP-1 macrophage cells.
Journal: Cytokine 20100801
Title: Novel plasminogen activator inhibitor-1-derived peptide protects against impairment of cerebrovasodilation after photothrombosis through inhibition of JNK MAPK.
Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20100801
Title: Effect of hyperthermia in combination with TRAIL on the JNK-Bim signal transduction pathway and growth of xenograft tumors.
Journal: Journal of cellular biochemistry 20100801
Title: The mechanism of fucoidan-induced apoptosis in leukemic cells: involvement of ERK1/2, JNK, glutathione, and nitric oxide.
Journal: Molecular carcinogenesis 20100801
Title: Nucleotide oligomerization domain 1 is a dominant pathway for NOS2 induction in vascular smooth muscle cells: comparison with Toll-like receptor 4 responses in macrophages.
Journal: British journal of pharmacology 20100801
Title: N-acetylcysteine protects alveolar epithelial cells from hydrogen peroxide-induced apoptosis through scavenging reactive oxygen species and suppressing c-Jun N-terminal kinase.
Journal: Experimental lung research 20100801
Title: Control of TrkA-induced cell death by JNK activation and differential expression of TrkA upon DNA damage.
Journal: Molecules and cells 20100801
Title: 8-Bromo-7-methoxychrysin-induced apoptosis of hepatocellular carcinoma cells involves ROS and JNK.
Journal: World journal of gastroenterology 20100721
Title: Amphetamines induce tissue factor and impair tissue factor pathway inhibitor: role of dopamine receptor type 4.
Journal: European heart journal 20100701
Title: Rolipram and SP600125 suppress the early increase in PTP1B expression during cerulein-induced pancreatitis in rats.
Journal: Pancreas 20100701
Title: Mycophenolic acid attenuates tumor necrosis factor-alpha-induced endothelin-1 production in human aortic endothelial cells.
Journal: Atherosclerosis 20100701
Title: Down-expression of PGC-1alpha partially mediated by JNK/c-Jun through binding to CRE site during apoptotic procedure in cerebellar granule neurons.
Journal: Journal of neuroscience research 20100701
Title: Caspases-2 and -8 are involved in the presenilin1/gamma-secretase-dependent cleavage of amyloid precursor protein after the induction of apoptosis.
Journal: Journal of neuroscience research 20100701
Title: Sorafenib combined vitamin K induces apoptosis in human pancreatic cancer cell lines through RAF/MEK/ERK and c-Jun NH2-terminal kinase pathways.
Journal: Journal of cellular physiology 20100701
Title: Chloramphenicol causes mitochondrial stress, decreases ATP biosynthesis, induces matrix metalloproteinase-13 expression, and solid-tumor cell invasion.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20100701
Title: JNK inhibition arrests cotranslational degradation.
Journal: Biochimica et biophysica acta 20100701
Title: Interaction of Pdcd4 with eIF4E inhibits the metastatic potential of hepatocellular carcinoma.
Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20100701
Title: c-Jun N-terminal kinase modulates oxidant stress and peroxynitrite formation independent of inducible nitric oxide synthase in acetaminophen hepatotoxicity.
Journal: Toxicology and applied pharmacology 20100701
Title: PAI-1-derived peptide EEIIMD prevents impairment of cerebrovasodilation by augmenting p38 MAPK upregulation after cerebral hypoxia/ischemia.
Journal: American journal of physiology. Heart and circulatory physiology 20100701
Title: Regulation of (pro)renin receptor expression by glucose-induced mitogen-activated protein kinase, nuclear factor-kappaB, and activator protein-1 signaling pathways.
Journal: Endocrinology 20100701
Title: Protein tyrosine kinase pathway-derived ROS/NO productions contribute to G2/M cell cycle arrest in evodiamine-treated human cervix carcinoma HeLa cells.
Journal: Free radical research 20100701
Title: Deciphering mechanisms controlling placental artery endothelial cell migration stimulated by vascular endothelial growth factor.
Journal: Endocrinology 20100701
Title: Mechanisms of IL-12 synthesis by human dendritic cells treated with the chemical sensitizer NiSO4.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20100701
Title: The JNK pathway modulates expression and phosphorylation of 4E-BP1 in MIN6 pancreatic beta-cells under oxidative stress conditions.
Journal: Cell biochemistry and function 20100701
Title: p75 neurotrophin receptor-mediated apoptosis in sympathetic neurons involves a biphasic activation of JNK and up-regulation of tumor necrosis factor-alpha-converting enzyme/ADAM17.
Journal: The Journal of biological chemistry 20100625
Title: Suppression of PMA-induced tumor cell invasion by dihydroartemisinin via inhibition of PKCalpha/Raf/MAPKs and NF-kappaB/AP-1-dependent mechanisms.
Journal: Biochemical pharmacology 20100615
Title: Role of MAP kinases in regulating expression of antioxidants and inflammatory mediators in mouse keratinocytes following exposure to the half mustard, 2-chloroethyl ethyl sulfide.
Journal: Toxicology and applied pharmacology 20100615
Title: Glucosamine regulation of LPS-mediated inflammation in human bronchial epithelial cells.
Journal: European journal of pharmacology 20100610
Title: Molecular mechanisms involving sigma receptor-mediated induction of MCP-1: implication for increased monocyte transmigration.
Journal: Blood 20100610
Title: The coffee diterpene kahweol sensitizes TRAIL-induced apoptosis in renal carcinoma Caki cells through down-regulation of Bcl-2 and c-FLIP.
Journal: Chemico-biological interactions 20100607
Title: Suppression of the androgen receptor function by quercetin through protein-protein interactions of Sp1, c-Jun, and the androgen receptor in human prostate cancer cells.
Journal: Molecular and cellular biochemistry 20100601
Title: Manganese-mediated up-regulation of HIF-1alpha protein in Hep2 human laryngeal epithelial cells via activation of the family of MAPKs.
Journal: Toxicology in vitro : an international journal published in association with BIBRA 20100601
Title: Deferoxamine mesylate is toxic for retinal pigment epithelium cells in vitro, and its toxicity is mediated by p38.
Journal: Cutaneous and ocular toxicology 20100601
Title: JNK pathway is required for TNCB-induced IL-18 expression in murine keratinocytes.
Journal: Toxicology in vitro : an international journal published in association with BIBRA 20100601
Title: Protective effect of sulforaphane on human vascular endothelial cells against lipopolysaccharide-induced inflammatory damage.
Journal: Cardiovascular toxicology 20100601
Title: The antimicrobial peptide LL37 induces the migration of human pulp cells: a possible adjunct for regenerative endodontics.
Journal: Journal of endodontics 20100601
Title: Inhibition of the JNK signal cascade conserves hearing against electrode insertion trauma-induced loss.
Journal: Cochlear implants international 20100601
Title: Role of oxidative stress and MAPK signaling in reference moist smokeless tobacco-induced HOK-16B cell death.
Journal: Toxicology letters 20100519
Title: Mycophenolic acid inhibits the phosphorylation of NF-kappaB and JNKs and causes a decrease in IL-8 release in H2O2-treated human renal proximal tubular cells.
Journal: Chemico-biological interactions 20100514
Title: Resveratrol enhances perforin expression and NK cell cytotoxicity through NKG2D-dependent pathways.
Journal: Journal of cellular physiology 20100501
Title: Palmitic acid promotes endothelial progenitor cells apoptosis via p38 and JNK mitogen-activated protein kinase pathways.
Journal: Atherosclerosis 20100501
Title: Human cytomegalovirus induces caspase-dependent apoptosis of megakaryocytic CHRF-288-11 cells by activating the JNK pathway.
Journal: International journal of hematology 20100501
Title: Differential functions of growth factor receptor-bound protein 7 (GRB7) and its variant GRB7v in ovarian carcinogenesis.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20100501
Title: SP600125, an inhibitor of c-Jun NH2-terminal kinase, blocks expression of angiotensin II-induced monocyte chemoattractant protein-1 in human mesangial cells.
Journal: World journal of pediatrics : WJP 20100501
Title: TNF-alpha reduces the Na+/K+ ATPase activity in LLC-PK1 cells by activating caspases and JNK and inhibiting NF-kappaB.
Journal: Cell biology international 20100427
Title: Cinnamaldehyde impairs high glucose-induced hypertrophy in renal interstitial fibroblasts.
Journal: Toxicology and applied pharmacology 20100415
Title: Blockage of JNK pathway enhances arsenic trioxide-induced apoptosis in human keratinocytes.
Journal: Toxicology and applied pharmacology 20100415
Title: Ghrelin inhibits cell apoptosis induced by lipotoxicity in pancreatic beta-cell line.
Journal: Regulatory peptides 20100409
Title: The role of p38 mitogen-activated protein kinase in serum-induced leukemia inhibitory factor secretion by bone marrow stromal cells from pediatric myelodysplastic syndromes.
Journal: Leukemia research 20100401
Title: Betacellulin protects from pancreatitis by activating stress-activated protein kinase.
Journal: Gastroenterology 20100401
Title: Regulation of multidrug resistance protein 1 by tumor necrosis factor alpha in cultured glial cells: involvement of nuclear factor-kappaB and c-Jun N-terminal kinase signaling pathways.
Journal: Molecular pharmacology 20100401
Title: Lead induces the expression of endoplasmic reticulum chaperones GRP78 and GRP94 in vascular endothelial cells via the JNK-AP-1 pathway.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20100401
Title: Peritonitis-induced peroxynitrite and lung damage depends on c-Jun NH2-terminal kinase signaling of hematopoietic cells.
Journal: Critical care medicine 20100401
Title: Testosterone membrane-initiated action in breast cancer cells: Interaction with the androgen signaling pathway and EPOR.
Journal: Molecular oncology 20100401
Title: Role of c-Jun N-terminal kinase (JNK) in regulating tumor necrosis factor-alpha (TNF-alpha) mediated increase of acetaminophen (APAP) and chlorpromazine (CPZ) toxicity in murine hepatocytes.
Journal: The Journal of toxicological sciences 20100401
Title: Heme oxygenase-1 mediates nicotine- and lipopolysaccharide-induced expression of cyclooxygenase-2 and inducible nitric oxide synthase in human periodontal ligament cells.
Journal: Journal of periodontal research 20100401
Title: Proinflammatory effects of muramyldipeptide on human gingival fibroblasts.
Journal: Journal of periodontal research 20100401
Title: Purification of a peptide from seahorse, that inhibits TPA-induced MMP, iNOS and COX-2 expression through MAPK and NF-kappaB activation, and induces human osteoblastic and chondrocytic differentiation.
Journal: Chemico-biological interactions 20100330
Title: Bisphenol A-induced aromatase activation is mediated by cyclooxygenase-2 up-regulation in rat testicular Leydig cells.
Journal: Toxicology letters 20100315
Title: Close association of p38 and JNK with plasminogen-dependent upregulation of PAI-1 in rat astrocytes in vitro.
Journal: Neuroscience letters 20100303
Title: Biophysical and X-ray crystallographic analysis of Mps1 kinase inhibitor complexes.
Journal: Biochemistry 20100302
Title: Contrasting patterns of Bim induction and neuroprotection in Bim-deficient mice between hippocampus and neocortex after status epilepticus.
Journal: Cell death and differentiation 20100301
Title: Edaravone improves the expression of nerve growth factor in human astrocytes subjected to hypoxia/reoxygenation.
Journal: Neuroscience research 20100301
Title: Estradiol protects the cochlea against gentamicin ototoxicity through inhibition of the JNK pathway.
Journal: Hearing research 20100301
Title: Toll-like receptor ligands cause proinflammatory and prodiabetic activation of adipocytes via phosphorylation of extracellular signal-regulated kinase and c-Jun N-terminal kinase but not interferon regulatory factor-3.
Journal: Endocrinology 20100301
Title: Acetaminophen induced acute liver failure via oxidative stress and JNK activation: protective role of taurine by the suppression of cytochrome P450 2E1.
Journal: Free radical research 20100301
Title: Butein induces G(2)/M phase arrest and apoptosis in human hepatoma cancer cells through ROS generation.
Journal: Cancer letters 20100227
Title: Surfactin induces apoptosis in human breast cancer MCF-7 cells through a ROS/JNK-mediated mitochondrial/caspase pathway.
Journal: Chemico-biological interactions 20100212
Title: Regulation of neurite outgrowth by interactions between the scaffolding protein, JNK-associated leucine zipper protein, and neuronal growth-associated protein superior cervical ganglia clone 10.
Journal: The Journal of biological chemistry 20100205
Title: Naphtho[1,2-b]furan-4,5-dione induces apoptosis and S-phase arrest of MDA-MB-231 cells through JNK and ERK signaling activation.
Journal: Toxicology in vitro : an international journal published in association with BIBRA 20100201
Title: Rotenone induces apoptosis in MCF-7 human breast cancer cell-mediated ROS through JNK and p38 signaling.
Journal: Molecular carcinogenesis 20100201
Title: Mechanisms involved in ultrafine carbon black-induced release of IL-6 from primary rat epithelial lung cells.
Journal: Toxicology in vitro : an international journal published in association with BIBRA 20100201
Title: Anti-adipogenesis by 6-thioinosine is mediated by downregulation of PPAR gamma through JNK-dependent upregulation of iNOS.
Journal: Cellular and molecular life sciences : CMLS 20100201
Title: Inhibition of Foxo1 mediates protective effects of ghrelin against lipotoxicity in MIN6 pancreatic beta-cells.
Journal: Peptides 20100201
Title: Effects of UVA on TNF-alpha, IL-1beta, and IL-10 expression levels in human keratinocytes and intervention studies with an antioxidant and a JNK inhibitor.
Journal: Photodermatology, photoimmunology & photomedicine 20100201
Title: Role of the JNK/c-Jun/AP-1 signaling pathway in galectin-1-induced T-cell death.
Journal: Cell death & disease 20100201
Title: Induction of tissue inhibitor of matrix metalloproteinase-2 by cholesterol depletion leads to the conversion of proMMP-2 into active MMP-2 in human dermal fibroblasts.
Journal: Experimental & molecular medicine 20100131
Title: Prevention of premature senescence requires JNK regulation of Bcl-2 and reactive oxygen species.
Journal: Oncogene 20100128
Title: Calcium-stimulated mitogen-activated protein kinase activation elicits Bcl-xL downregulation and Bak upregulation in notexin-treated human neuroblastoma SK-N-SH cells.
Journal: Journal of cellular physiology 20100101
Title: Modulation of hepatic fibrosis by c-Jun-N-terminal kinase inhibition.
Journal: Gastroenterology 20100101
Title: Gene regulation of CYP4F11 in human keratinocyte HaCaT cells.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20100101
Title: c-Jun N-terminal kinase 1 is required for cordycepin-mediated induction of G2/M cell-cycle arrest via p21WAF1 expression in human colon cancer cells.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20100101
Title: Apoptosis induction in BEFV-infected Vero and MDBK cells through Src-dependent JNK activation regulates caspase-3 and mitochondria pathways.
Journal: Veterinary research 20100101
Title: JNK mitogen-activated protein kinase limits calcium-dependent chloride secretion across colonic epithelial cells.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20100101
Title: Cadmium induces intracellular Ca2+- and H2O2-dependent apoptosis through JNK- and p53-mediated pathways in skin epidermal cell line.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20100101
Title: (-)-Epigallocatechin-3-gallate decreases thrombin/paclitaxel-induced endothelial tissue factor expression via the inhibition of c-Jun terminal NH2 kinase phosphorylation.
Journal: Biochemical and biophysical research communications 20100101
Title: Transcriptional regulation of the presenilin-1 gene controls gamma-secretase activity.
Journal: Frontiers in bioscience (Elite edition) 20100101
Title: Expression genetics identifies spinal mechanisms supporting formalin late phase behaviors.
Journal: Molecular pain 20100101
Title: Histone deacetylase inhibitors induce apoptosis in human eosinophils and neutrophils.
Journal: Journal of inflammation (London, England) 20100101
Title: Induction of LRF-1/ATF3 by vasopressin in hepatocytes: role of MAP kinases.
Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20100101
Title: Inhibition of c-Jun N-terminal kinase by SP600125: a cDNA microarray analysis.
Journal: Cancer genomics & proteomics 20100101
Title: Pharmacological inhibition of c-Jun N-terminal kinase signaling prevents cardiomyopathy caused by mutation in LMNA gene.
Journal: Biochimica et biophysica acta 20100101
Title: Resveratrol differentially modulates inflammatory responses of microglia and astrocytes.
Journal: Journal of neuroinflammation 20100101
Title: Protective role of taurine against arsenic-induced mitochondria-dependent hepatic apoptosis via the inhibition of PKCdelta-JNK pathway.
Journal: PloS one 20100101
Title: Doxorubicin induces apoptosis in H9c2 cardiomyocytes: role of overexpressed eukaryotic translation initiation factor 5A.
Journal: Biological & pharmaceutical bulletin 20100101
Title: Platelet-activating factor receptor mediates oxidized low density lipoprotein-induced migration of bone marrow-derived mesenchymal stem cells.
Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20100101
Title: c-Jun NH2-terminal kinase-dependent upregulation of DR5 mediates cooperative induction of apoptosis by perifosine and TRAIL.
Journal: Molecular cancer 20100101
Title: Ligand-independent activation of the androgen receptor by insulin-like growth factor-I and the role of the MAPK pathway in skeletal muscle cells.
Journal: Molecules and cells 20091231
Title: NMDA receptors are involved in upstream of the spinal JNK activation in morphine antinociceptive tolerance.
Journal: Neuroscience letters 20091225
Title: Role of the nuclear receptors HNF4 alpha, PPAR alpha, and LXRs in the TNF alpha-mediated inhibition of human apolipoprotein A-I gene expression in HepG2 cells.
Journal: Biochemistry 20091222
Title: Inhibition of c-Jun N-terminal kinase enhances temozolomide-induced cytotoxicity in human glioma cells.
Journal: Journal of neuro-oncology 20091201
Title: Glycosaminoglycans and syndecan-4 are involved in SDF-1/CXCL12-mediated invasion of human epitheloid carcinoma HeLa cells.
Journal: Biochimica et biophysica acta 20091201
Title: Regulation of Lhb and Egr1 gene expression by GNRH pulses in rat pituitaries is both c-Jun N-terminal kinase (JNK)- and extracellular signal-regulated kinase (ERK)-dependent.
Journal: Biology of reproduction 20091201
Title: c-Jun NH2-terminal kinase is crucially involved in renal tubulo-interstitial inflammation.
Journal: The Journal of pharmacology and experimental therapeutics 20091201
Title: ROS inhibit the expression of testicular steroidogenic enzyme genes via the suppression of Nur77 transactivation.
Journal: Free radical biology & medicine 20091201
Title: Doxorubicin induces senescence or apoptosis in rat neonatal cardiomyocytes by regulating the expression levels of the telomere binding factors 1 and 2.
Journal: American journal of physiology. Heart and circulatory physiology 20091201
Title: Local secretion of urocortin 1 promotes microvascular permeability during lipopolysaccharide-induced inflammation.
Journal: Endocrinology 20091201
Title: Forkhead box O1/pancreatic and duodenal homeobox 1 intracellular translocation is regulated by c-Jun N-terminal kinase and involved in prostaglandin E2-induced pancreatic beta-cell dysfunction.
Journal: Endocrinology 20091201
Title: Mechanism of lapatinib-mediated radiosensitization of breast cancer cells is primarily by inhibition of the Raf>MEK>ERK mitogen-activated protein kinase cascade and radiosensitization of lapatinib-resistant cells restored by direct inhibition of MEK.
Journal: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20091201
Title: Triclosan inhibits tumor necrosis factor-alpha-stimulated urokinase production in human gingival fibroblasts.
Journal: Journal of periodontal research 20091201
Title: Abeta(31-35)-induced neuronal apoptosis is mediated by JNK-dependent extrinsic apoptosis pathway.
Journal: Neuroscience bulletin 20091201
Title: Basal c-Jun NH2-terminal protein kinase activity is essential for survival and proliferation of T-cell acute lymphoblastic leukemia cells.
Journal: Molecular cancer therapeutics 20091201
Title: c-Jun N-terminal kinase negatively regulates epidermal growth factor-induced cyclooxygenase-2 expression in oral squamous cell carcinoma cell lines.
Journal: European journal of oral sciences 20091201
Title: Cyclin D1 induction by benzo[a]pyrene-7,8-diol-9,10-epoxide via the phosphatidylinositol 3-kinase/Akt/MAPK- and p70s6k-dependent pathway promotes cell transformation and tumorigenesis.
Journal: The Journal of biological chemistry 20091127
Title: Enterobacter sakazakii targets DC-SIGN to induce immunosuppressive responses in dendritic cells by modulating MAPKs.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20091115
Title: HMGB1 enhances the proinflammatory activity of lipopolysaccharide by promoting the phosphorylation of MAPK p38 through receptor for advanced glycation end products.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20091115
Title: Constitutive and oxidative-stress-induced expression of VEGF in the RPE are differently regulated by different Mitogen-activated protein kinases.
Journal: Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20091101
Title: Matrix metalloproteinase-14 mediates a phenotypic shift in the airways to increase mucin production.
Journal: American journal of respiratory and critical care medicine 20091101
Title: Inhibition of the JNK signalling pathway enhances proteasome inhibitor-induced apoptosis of kidney cancer cells by suppression of BAG3 expression.
Journal: British journal of pharmacology 20091101
Title: Glucose-regulated protein 78 inhibits scavenger receptor A-mediated internalization of acetylated low density lipoprotein.
Journal: Journal of molecular and cellular cardiology 20091101
Title: Protection from diclofenac-induced small intestinal injury by the JNK inhibitor SP600125 in a mouse model of NSAID-associated enteropathy.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20091101
Title: JNK inhibitor protects dopaminergic neurons by reducing COX-2 expression in the MPTP mouse model of subacute Parkinson's disease.
Journal: Journal of the neurological sciences 20091015
Title: Cordycepin causes p21WAF1-mediated G2/M cell-cycle arrest by regulating c-Jun N-terminal kinase activation in human bladder cancer cells.
Journal: Archives of biochemistry and biophysics 20091015
Title: Tpl2 is a key mediator of arsenite-induced signal transduction.
Journal: Cancer research 20091015
Title: PDGF stimulation of Müller cell proliferation: Contributions of c-JNK and the PI3K/Akt pathway.
Journal: Biochemical and biophysical research communications 20091009
Title: Effect of TLR3 and TLR7 activation in uterine NK cells from non-obese diabetic (NOD) mice.
Journal: Journal of reproductive immunology 20091001
Title: JNK-dependent NFATc1 pathway positively regulates IL-13 gene expression induced by (-)-epigallocatechin-3-gallate in human basophilic KU812 cells.
Journal: Free radical biology & medicine 20091001
Title: Effects of prostaglandin D2 on Na-dependent phosphate transport activity and its intracellular signaling mechanism in osteoblast-like cells.
Journal: Prostaglandins, leukotrienes, and essential fatty acids 20091001
Title: Taurine prevents arsenic-induced cardiac oxidative stress and apoptotic damage: role of NF-kappa B, p38 and JNK MAPK pathway.
Journal: Toxicology and applied pharmacology 20091001
Title: Anti-apoptotic action of hydrogen sulfide is associated with early JNK inhibition.
Journal: Cell biology international 20091001
Title: Glucosamine inhibits IL-1beta-mediated IL-8 production in prostate cancer cells by MAPK attenuation.
Journal: Journal of cellular biochemistry 20091001
Title: Ketoconazole-induced JNK phosphorylation and subsequent cell death via apoptosis in human osteosarcoma cells.
Journal: Toxicology in vitro : an international journal published in association with BIBRA 20091001
Title: Syndecan-1 and syndecan-4 are involved in RANTES/CCL5-induced migration and invasion of human hepatoma cells.
Journal: Biochimica et biophysica acta 20091001
Title: Characterization of CRTAM gene promoter: AP-1 transcription factor control its expression in human T CD8 lymphocytes.
Journal: Molecular immunology 20091001
Title: A JNK inhibitor SP600125 induces defective cytokinesis and enlargement in P19 embryonal carcinoma cells.
Journal: Cell biochemistry and function 20091001
Title: Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
Journal: Nature chemical biology 20091001
Title: [Effects of sp600125 on acetaldehyde stimulated hepatic stellate cells].
Journal: Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20091001
Title: JNK inhibitor SP600125 promotes the formation of polymerized tubulin, leading to G2/M phase arrest, endoreduplication, and delayed apoptosis.
Journal: Experimental & molecular medicine 20090930
Title: SP600125, an inhibitor of Jnk pathway, reduces viability of relatively resistant cancer cells to doxorubicin.
Journal: Biochemical and biophysical research communications 20090925
Title: JNK1-dependent PUMA expression contributes to hepatocyte lipoapoptosis.
Journal: The Journal of biological chemistry 20090925
Title: 1,3-Dinitrobenzene induces apoptosis in TM4 mouse Sertoli cells: Involvement of the c-Jun N-terminal kinase (JNK) MAPK pathway.
Journal: Toxicology letters 20090910
Title: FGF2 stimulates the proliferation of human mesenchymal stem cells through the transient activation of JNK signaling.
Journal: FEBS letters 20090903
Title: Silencing of TNF-alpha receptors coordinately suppresses TNF-alpha expression through NF-kappaB activation blockade in THP-1 macrophage.
Journal: FEBS letters 20090903
Title: Interferon-gamma priming is involved in the activation of arginase by oligodeoxinucleotides containing CpG motifs in murine macrophages.
Journal: Immunology 20090901
Title: Quercetin inhibits IL-1 beta-induced ICAM-1 expression in pulmonary epithelial cell line A549 through the MAPK pathways.
Journal: Molecular biology reports 20090901
Title: Arecoline-stimulated connective tissue growth factor production in human buccal mucosal fibroblasts: Modulation by curcumin.
Journal: Oral oncology 20090901
Title: Biphasic effect of cadmium on cell proliferation in human embryo lung fibroblast cells and its molecular mechanism.
Journal: Toxicology in vitro : an international journal published in association with BIBRA 20090901
Title: Involvement of C-jun NH2-terminal kinase and apoptosis induced factor in apoptosis induced by deglycosylated bleomycin in laryngeal carcinoma cells.
Journal: Cell biology international 20090901
Title: Fenofibrate differentially regulates plasminogen activator inhibitor-1 gene expression via adenosine monophosphate-activated protein kinase-dependent induction of orphan nuclear receptor small heterodimer partner.
Journal: Hepatology (Baltimore, Md.) 20090901
Title: Inhibition of basal p38 or JNK activity enhances epithelial barrier function through differential modulation of claudin expression.
Journal: American journal of physiology. Cell physiology 20090901
Title: The JNK MAP kinase pathway contributes to the development of endotoxin-induced diaphragm caspase activation.
Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20090901
Title: Oncogenic Ras signals through activation of both phosphoinositide 3-kinase and Rac1 to induce c-Jun NH2-terminal kinase-mediated, caspase-independent cell death.
Journal: Molecular cancer research : MCR 20090901
Title: [Pathogenetic role of tissue factor in endothelial-injury in graft-versus-host disease].
Journal: Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20090901
Title: Arachidonic acid-induced apoptosis of human neuroblastoma SK-N-SH cells is mediated through mitochondrial alteration elicited by ROS and Ca(2+)-evoked activation of p38alpha MAPK and JNK1.
Journal: Toxicology 20090821
Title: Fluoride-induced cyclooxygenase-2 expression and prostaglandin E2 production in A549 human pulmonary epithelial cells.
Journal: Toxicology letters 20090810
Title: Activation of JNK and PAK2 is essential for citrinin-induced apoptosis in a human osteoblast cell line.
Journal: Environmental toxicology 20090801
Title: Oleoylethanolamide, a natural ligand for PPAR-alpha, inhibits insulin receptor signalling in HTC rat hepatoma cells.
Journal: Biochimica et biophysica acta 20090801
Title: Regulation of Bax by c-Jun NH2-terminal kinase and Bcl-xL in vinblastine-induced apoptosis.
Journal: Biochemical pharmacology 20090801
Title: Nobiletin, a dietary phytochemical, inhibits vascular smooth muscle cells proliferation via calcium-mediated c-Jun N-terminal kinases pathway.
Journal: European journal of pharmacology 20090801
Title: Oxidized {alpha}1-antitrypsin stimulates the release of monocyte chemotactic protein-1 from lung epithelial cells: potential role in emphysema.
Journal: American journal of physiology. Lung cellular and molecular physiology 20090801
Title: Genistein inhibits cell growth by modulating various mitogen-activated protein kinases and AKT in cervical cancer cells.
Journal: Annals of the New York Academy of Sciences 20090801
Title: Ginkgolide B induces apoptosis via activation of JNK and p21-activated protein kinase 2 in mouse embryonic stem cells.
Journal: Annals of the New York Academy of Sciences 20090801
Title: Gallic acid induces neuronal cell death through activation of c-Jun N-terminal kinase and downregulation of Bcl-2.
Journal: Annals of the New York Academy of Sciences 20090801
Title: Cobalt protoporphyrin inhibition of lipopolysaccharide or lipoteichoic acid-induced nitric oxide production via blocking c-Jun N-terminal kinase activation and nitric oxide enzyme activity.
Journal: Chemico-biological interactions 20090715
Title: Role of Paris PM(2.5) components in the pro-inflammatory response induced in airway epithelial cells.
Journal: Toxicology 20090710
Title: Regulation of c-Fos and c-Jun gene expression by phospholipase C activity in adult cardiomyocytes.
Journal: Molecular and cellular biochemistry 20090701
Title: Endogenous IGFBP-3 is required for both growth factor-stimulated cell proliferation and cytokine-induced apoptosis in mammary epithelial cells.
Journal: Journal of cellular physiology 20090701
Title: Upregulation of proinflammatory cytokines and NO production in BV-activated avian macrophage-like cell line (HD11) requires MAPK and NF-kappaB pathways.
Journal: International immunopharmacology 20090701
Title: Block-copolymer micelles as carriers of cell signaling modulators for the inhibition of JNK in human islets of Langerhans.
Journal: Biomaterials 20090701
Title: Pterostilbene inhibited tumor invasion via suppressing multiple signal transduction pathways in human hepatocellular carcinoma cells.
Journal: Carcinogenesis 20090701
Title: Blocking UV-induced eIF2alpha phosphorylation with small molecule inhibitors of GCN2.
Journal: Chemical biology & drug design 20090701
Title: JNK/AP-1 pathway is involved in tumor necrosis factor-alpha induced expression of vascular endothelial growth factor in MCF7 cells.
Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20090701
Title: Cadmium stimulates the expression of vascular cell adhesion molecule-1 (VCAM-1) via p38 mitogen-activated protein kinase (MAPK) and JNK activation in cerebrovascular endothelial cells.
Journal: Journal of pharmacological sciences 20090701
Title: Effects of polychlorinated biphenyls on the neutrophil NADPH oxidase system.
Journal: Toxicology letters 20090622
Title: NADPH oxidase and ERK1/2 are involved in cadmium induced-STAT3 activation in HepG2 cells.
Journal: Toxicology letters 20090622
Title: Inhibiting JNK dephosphorylation and induction of apoptosis by novel anticancer agent NSC-741909 in cancer cells.
Journal: The Journal of biological chemistry 20090619
Title: Distinct Nrf1/2-independent mechanisms mediate As 3+-induced glutamate-cysteine ligase subunit gene expression in murine hepatocytes.
Journal: Free radical biology & medicine 20090615
Title: Activation of ERK and JNK signaling pathways by mycotoxin citrinin in human cells.
Journal: Toxicology and applied pharmacology 20090615
Title: Zinc protoporphyrin inhibition of lipopolysaccharide-, lipoteichoic acid-, and peptidoglycan-induced nitric oxide production through stimulating iNOS protein ubiquitination.
Journal: Toxicology and applied pharmacology 20090615
Title: Characterization of natural killer cells in nonobese diabetic/severely compromised immunodeficient mice during pregnancy.
Journal: Fertility and sterility 20090601
Title: Hydrogen peroxide-induced neuronal apoptosis is associated with inhibition of protein phosphatase 2A and 5, leading to activation of MAPK pathway.
Journal: The international journal of biochemistry & cell biology 20090601
Title: The inhibition of JNK and p38 MAPKs downregulates IL-10 and differentially affects c-Jun gene expression in human monocytes.
Journal: Immunopharmacology and immunotoxicology 20090601
Title: Inhibition of uncoupling protein 2 by genipin reduces insulin-stimulated glucose uptake in 3T3-L1 adipocytes.
Journal: Archives of biochemistry and biophysics 20090601
Title: The protein synthesis inhibitor anisomycin induces macrophage apoptosis in rabbit atherosclerotic plaques through p38 mitogen-activated protein kinase.
Journal: The Journal of pharmacology and experimental therapeutics 20090601
Title: Inhibition of c-Jun NH2-terminal kinase switches Smad3 signaling from oncogenesis to tumor- suppression in rat hepatocellular carcinoma.
Journal: Hepatology (Baltimore, Md.) 20090601
Title: Prevention of hepatocarcinogenesis and increased susceptibility to acetaminophen-induced liver failure in transaldolase-deficient mice by N-acetylcysteine.
Journal: The Journal of clinical investigation 20090601
Title: Acetaminophen and lipopolysaccharide act in synergy for the production of pro-inflammatory cytokines in murine RAW264.7 macrophages.
Journal: Journal of immunotoxicology 20090601
Title: PHR regulates growth cone pausing at intermediate targets through microtubule disassembly.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20090520
Title: Cocoa procyanidins attenuate 4-hydroxynonenal-induced apoptosis of PC12 cells by directly inhibiting mitogen-activated protein kinase kinase 4 activity.
Journal: Free radical biology & medicine 20090515
Title: Up-regulation of endothelial monocyte chemoattractant protein-1 by coplanar PCB77 is caveolin-1-dependent.
Journal: Toxicology and applied pharmacology 20090515
Title: Statins induce apoptosis in ovarian cancer cells through activation of JNK and enhancement of Bim expression.
Journal: Cancer chemotherapy and pharmacology 20090501
Title: JNK and p38 MAPK are independently involved in tributyltin-mediated cell death in rainbow trout (Oncorhynchus mykiss) RTG-2 cells.
Journal: Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20090501
Title: JNK inhibition sensitises hepatocellular carcinoma cells but not normal hepatocytes to the TNF-related apoptosis-inducing ligand.
Journal: Gut 20090501
Title: Insufficiency of pro-heparin-binding epidermal growth factor-like growth factor shedding enhances hypoxic cell death in H9c2 cardiomyoblasts via the activation of caspase-3 and c-Jun N-terminal kinase.
Journal: The Journal of biological chemistry 20090501
Title: JNK is constitutively active in mantle cell lymphoma: cell cycle deregulation and polyploidy by JNK inhibitor SP600125.
Journal: The Journal of pathology 20090501
Title: Echographic detection of diethylnitrosamine-induced liver tumors in rats and the effect of the intratumoral injection of an inhibitor of c-Jun N-terminal kinase.
Journal: Journal of gastroenterology and hepatology 20090501
Title: NaF activates MAPKs and induces apoptosis in odontoblast-like cells.
Journal: Journal of dental research 20090501
Title: Regulation of expression of matrix metalloproteinase-9 by JNK in Raw 264.7 cells: presence of inhibitory factor(s) suppressing MMP-9 induction in serum and conditioned media.
Journal: Experimental & molecular medicine 20090430
Title: Inhibition of JNK enhances TGF-beta1-activated Smad2 signaling in mouse embryonic lung.
Journal: Pediatric research 20090401
Title: Endoplasmic reticulum stress-mediated autophagy/apoptosis induced by capsaicin (8-methyl-N-vanillyl-6-nonenamide) and dihydrocapsaicin is regulated by the extent of c-Jun NH2-terminal kinase/extracellular signal-regulated kinase activation in WI38 lung epithelial fibroblast cells.
Journal: The Journal of pharmacology and experimental therapeutics 20090401
Title: The TAK1-JNK cascade is required for IRF3 function in the innate immune response.
Journal: Cell research 20090401
Title: Expression of inflammatory genes induced by beta-amyloid peptides in human brain endothelial cells and in Alzheimer's brain is mediated by the JNK-AP1 signaling pathway.
Journal: Neurobiology of disease 20090401
Title: N-acetyl cysteine mediates protection from 2-hydroxyethyl methacrylate induced apoptosis via nuclear factor kappa B-dependent and independent pathways: potential involvement of JNK.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20090401
Title: TGF-beta effects on airway smooth muscle cell proliferation, VEGF release and signal transduction pathways.
Journal: Respirology (Carlton, Vic.) 20090401
Title: Tumour necrosis factor alpha stimulates the production of monocyte chemoattractants by extravillous trophoblast cells via differential activation of MAPK pathways.
Journal: Placenta 20090401
Title: Tissue inhibitor of metalloproteinase-3 inhibits neonatal mouse cardiomyocyte proliferation via EGFR/JNK/SP-1 signaling.
Journal: American journal of physiology. Cell physiology 20090401
Title: A dual leucine kinase-dependent axon self-destruction program promotes Wallerian degeneration.
Journal: Nature neuroscience 20090401
Title: Trans-Zeatin inhibits UVB-induced matrix metalloproteinase-1 expression via MAP kinase signaling in human skin fibroblasts.
Journal: International journal of molecular medicine 20090401
Title: Chronic high-dose morphine treatment promotes SH-SY5Y cell apoptosis via c-Jun N-terminal kinase-mediated activation of mitochondria-dependent pathway.
Journal: The FEBS journal 20090401
Title: Neuroprotection by c-Jun NH2-terminal kinase inhibitor SP600125 against potassium deprivation-induced apoptosis involves the Akt pathway and inhibition of cell cycle reentry.
Journal: Neuroscience 20090331
Title: Angiotensin II induces MMP 2 activity via FAK/JNK pathway in human endothelial cells.
Journal: Biochemical and biophysical research communications 20090320
Title: Ultrafine particles from diesel engines induce vascular oxidative stress via JNK activation.
Journal: Free radical biology & medicine 20090315
Title: Up-regulation of CAR expression through Elk-1 in HepG2 and SW480 cells by serum starvation stress.
Journal: FEBS letters 20090304
Title: Glial fibrillary acidic protein promoter targets pancreatic stellate cells.
Journal: Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20090301
Title: Role of mitogen-activated protein kinase cascades in inducible nitric oxide synthase expression by lipopolysaccharide in a rat Schwann cell line.
Journal: Neurochemical research 20090301
Title: Inhibition of the activity of Rho-kinase reduces cardiomyocyte apoptosis in heart ischemia/reperfusion via suppressing JNK-mediated AIF translocation.
Journal: Clinica chimica acta; international journal of clinical chemistry 20090301
Title: Metallic haptens induce differential phenotype of human dendritic cells through activation of mitogen-activated protein kinase and NF-kappaB pathways.
Journal: Toxicology in vitro : an international journal published in association with BIBRA 20090301
Title: Blockage by SP600125 of Fcepsilon receptor-induced degranulation and cytokine gene expression in mast cells is mediated through inhibition of phosphatidylinositol 3-kinase signalling pathway.
Journal: Journal of biochemistry 20090301
Title: Sanguinarine induces apoptosis in A549 human lung cancer cells primarily via cellular glutathione depletion.
Journal: Toxicology in vitro : an international journal published in association with BIBRA 20090301
Title: Regulation of endothelin-1-induced interleukin-6 production by Ca2+ influx in human airway smooth muscle cells.
Journal: European journal of pharmacology 20090301
Title: TNF-alpha reduces the level of Staphylococcus epidermidis internalization by bovine endothelial cells.
Journal: FEMS microbiology letters 20090301
Title: C-jun N-terminal kinase-mediated signaling is essential for Staphylococcus aureus-induced U937 apoptosis.
Journal: Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih 20090301
Title: Role of MAPKs in platinum-induced neuronal apoptosis.
Journal: Neurotoxicology 20090301
Title: The pivotal role of c-Jun NH2-terminal kinase-mediated Beclin 1 expression during anticancer agents-induced autophagy in cancer cells.
Journal: Oncogene 20090212
Title: Regulatory mechanisms of SNAT2, an amino acid transporter, in L6 rat skeletal muscle cells by insulin, osmotic shock and amino acid deprivation.
Journal: Amino acids 20090201
Title: Daxx functions as a scaffold of a protein assembly constituted by GLUT4, JNK1 and KIF5B.
Journal: Journal of cellular physiology 20090201
Title: Differential roles of MAPKs and MSK1 signalling pathways in the regulation of c-Jun during phenylephrine-induced cardiac myocyte hypertrophy.
Journal: Molecular and cellular biochemistry 20090201
Title: c-Jun N-terminal kinase (JNK1) upregulates XIAP-associated factor 1 (XAF1) through interferon regulatory factor 1 (IRF-1) in gastrointestinal cancer.
Journal: Carcinogenesis 20090201
Title: Effect of curcumin on acidic pH-induced expression of IL-6 and IL-8 in human esophageal epithelial cells (HET-1A): role of PKC, MAPKs, and NF-kappaB.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20090201
Title: Curcumin, a potential inhibitor of up-regulation of TNF-alpha and IL-6 induced by palmitate in 3T3-L1 adipocytes through NF-kappaB and JNK pathway.
Journal: Biomedical and environmental sciences : BES 20090201
Title: SP600125 negatively regulates the mammalian target of rapamycin via ATF4-induced Redd1 expression.
Journal: FEBS letters 20090105
Title: 7-Ketocholesterol upregulates interleukin-6 via mechanisms that are distinct from those of tumor necrosis factor-alpha, in vascular smooth muscle cells.
Journal: Journal of vascular research 20090101
Title: TNF-alpha production in the skin.
Journal: Archives of dermatological research 20090101
Title: Enhanced induction of LPS-induced fibroblast MCP-1 by interferon-gamma: involvement of JNK and MAPK phosphatase-1.
Journal: Cellular immunology 20090101
Title: AP-1 and ERK1 but not p38 nor JNK is required for CRPV early protein 2-dependent MMP-9 promoter activation in rabbit epithelial cells.
Journal: Virus research 20090101
Title: Oxidative stress resistance through blocking Hsp60 translocation followed by SAPK/JNK inhibition in aged human diploid fibroblasts.
Journal: Cell biochemistry and function 20090101
Title: Induction of apoptosis in human leukemia cells by grape seed extract occurs via activation of c-Jun NH2-terminal kinase.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20090101
Title: Neuronal injury induces cytokine-induced neutrophil chemoattractant-1 (CINC-1) production in astrocytes.
Journal: Journal of pharmacological sciences 20090101
Title: Activation of c-Jun N-terminal kinase cascades is involved in part of the neuronal degeneration induced by trimethyltin in cortical neurons of mice.
Journal: Journal of pharmacological sciences 20090101
Title: Apoptosis induction by oxidized glycated LDL in human retinal capillary pericytes is independent of activation of MAPK signaling pathways.
Journal: Molecular vision 20090101
Title: Cisplatin primes murine peritoneal macrophages for enhanced expression of nitric oxide, proinflammatory cytokines, TLRs, transcription factors and activation of MAP kinases upon co-incubation with L929 cells.
Journal: Immunobiology 20090101
Title: The role of c-Jun N-terminal kinases 1/2 in transforming growth factor beta(1)-induced expression of connective tissue growth factor and scar formation in the cornea.
Journal: The Journal of international medical research 20090101
Title: The JNK pathway amplifies and drives subcellular changes in tau phosphorylation.
Journal: Neuropharmacology 20090101
Title: Nitric oxide induces cell death by regulating anti-apoptotic BCL-2 family members.
Journal: PloS one 20090101
Title: The proliferation and migration effects of huangqi on RSC96 Schwann cells.
Journal: The American journal of Chinese medicine 20090101
Title: Protective effects of SP600125 in a diet-induced rat model of non-alcoholic steatohepatitis.
Journal: Scandinavian journal of gastroenterology 20090101
Title: Transcription of the protein kinase C-delta gene is activated by JNK through c-Jun and ATF2 in response to the anticancer agent doxorubicin.
Journal: Experimental & molecular medicine 20081231
Title: Cardiotrophin-1 induces intercellular adhesion molecule-1 expression by nuclear factor kappaB activation in human umbilical vein endothelial cells.
Journal: Chinese medical journal 20081220
Title: Increased c-Jun-NH2-kinase signaling in neurofibromatosis-1 heterozygous microglia drives microglia activation and promotes optic glioma proliferation.
Journal: Cancer research 20081215
Title: Brefeldin A activates CHOP promoter at the AARE, ERSE and AP-1 elements.
Journal: Molecular and cellular biochemistry 20081201
Title: Realgar-induced differentiation is associated with MAPK pathways in HL-60 cells.
Journal: Cell biology international 20081201
Title: Phosphorylation of TRPV1 by neurokinin-1 receptor agonist exaggerates the capsaicin-mediated substance P release from cultured rat dorsal root ganglion neurons.
Journal: Neuropharmacology 20081201
Title: o,p'-DDT induces cyclooxygenase-2 gene expression in murine macrophages: Role of AP-1 and CRE promoter elements and PI3-kinase/Akt/MAPK signaling pathways.
Journal: Toxicology and applied pharmacology 20081201
Title: Astrocytic proliferation and mitochondrial dysfunction induced by accumulated glutaric acidemia I (GAI) metabolites: possible implications for GAI pathogenesis.
Journal: Neurobiology of disease 20081201
Title: In vitro and in vivo induction of apoptosis by capsaicin in pancreatic cancer cells is mediated through ROS generation and mitochondrial death pathway.
Journal: Apoptosis : an international journal on programmed cell death 20081201
Title: Phosphatidylinositol acts through mitogen-activated protein kinase to stimulate hepatic apolipoprotein A-I secretion.
Journal: Metabolism: clinical and experimental 20081201
Title: [Impact of PTEN gene knockout in human breast carcinoma MCF-7 cells on activity of JNK pathway].
Journal: Ai zheng = Aizheng = Chinese journal of cancer 20081201
Title: [The influence of JNK inhibitor on hemodynamics after ischemia/reperfusion injury to the heart in rats].
Journal: Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue 20081201
Title: Involvement of regulatory elements on corticotropin-releasing factor gene promoter in hypothalamic 4B cells.
Journal: Journal of endocrinological investigation 20081201
Title: JNK1 regulates histone acetylation in trigeminal neurons following chemical stimulation.
Journal: Biochemical and biophysical research communications 20081128
Title: Reciprocal influences of CB1 cannabinoid receptor agonists on ERK and JNK signalling in N1E-115 cells.
Journal: FEBS letters 20081126
Title: Virtual screening to successfully identify novel janus kinase 3 inhibitors: a sequential focused screening approach.
Journal: Journal of medicinal chemistry 20081113
Title: Selenium attenuates pro-inflammatory gene expression in macrophages.
Journal: Molecular nutrition & food research 20081101
Title: Egr-1 mRNA induction by medium flow involves mRNA stabilization and is enhanced by the p38 inhibitor SB203580 in osteoblast-like cells.
Journal: Acta physiologica (Oxford, England) 20081101
Title: Initiation of caspase-independent death in mouse mesangial cells by Cd2+: involvement of p38 kinase and CaMK-II.
Journal: Journal of cellular physiology 20081101
Title: IL-6/sIL-6R enhances cathepsin B and L production via caveolin-1-mediated JNK-AP-1 pathway in human gingival fibroblasts.
Journal: Journal of cellular physiology 20081101
Title: Curcumin inhibits VEGF-mediated angiogenesis in human intestinal microvascular endothelial cells through COX-2 and MAPK inhibition.
Journal: Gut 20081101
Title: Phosphorylation of claudin-4 is required for tight junction formation in a human keratinocyte cell line.
Journal: Experimental cell research 20081101
Title: Involvement of the PI3K/Akt pathway in estrogen-mediated regulation of human CYP7B1: identification of CYP7B1 as a novel target for PI3K/Akt and MAPK signalling.
Journal: The Journal of steroid biochemistry and molecular biology 20081101
Title: Mechanism of signal transduction in tumor necrosis factor-like weak inducer of apoptosis-induced matrix degradation by MMP-3 upregulation in disc tissues.
Journal: Spine 20081101
Title: Activation of peripheral ephrinBs/EphBs signaling induces hyperalgesia through a MAPKs-mediated mechanism in mice.
Journal: Pain 20081031
Title: Peroxisome proliferator-activated receptor gamma down-regulates follistatin in intestinal epithelial cells through SP1.
Journal: The Journal of biological chemistry 20081031
Title: IL-18 enhances ULBP2 expression through the MAPK pathway in leukemia cells.
Journal: Immunology letters 20081030
Title: The role of p38 MAPK and JNK in Arsenic trioxide-induced mitochondrial cell death in human cervical cancer cells.
Journal: Journal of cellular physiology 20081001
Title: (-)-Epigallocatechin gallate inhibits basic fibroblast growth factor-stimulated interleukin-6 synthesis in osteoblasts.
Journal: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20081001
Title: Expression and regulation of c-Jun N-terminal kinase (JNK) in endometrial cells in vivo and in vitro.
Journal: Histochemistry and cell biology 20081001
Title: TLR4 signaling induces B7-H1 expression through MAPK pathways in bladder cancer cells.
Journal: Cancer investigation 20081001
Title: The alpha1D-adrenergic receptor induces vascular smooth muscle apoptosis via a p53-dependent mechanism.
Journal: Molecular pharmacology 20081001
Title: A novel arsenical has antitumor activity toward As2O3-resistant and MRP1/ABCC1-overexpressing cell lines.
Journal: Leukemia 20081001
Title: Cadmium activates the mitogen-activated protein kinase (MAPK) pathway via induction of reactive oxygen species and inhibition of protein phosphatases 2A and 5.
Journal: Free radical biology & medicine 20081001
Title: A combination of sulindac and arsenic trioxide synergistically induces apoptosis in human lung cancer H1299 cells via c-Jun NH2-terminal kinase-dependent Bcl-xL phosphorylation.
Journal: Lung cancer (Amsterdam, Netherlands) 20080901
Title: Proinflammatory effect of sodium 4-phenylbutyrate in deltaF508-cystic fibrosis transmembrane conductance regulator lung epithelial cells: involvement of extracellular signal-regulated protein kinase 1/2 and c-Jun-NH2-terminal kinase signaling.
Journal: The Journal of pharmacology and experimental therapeutics 20080901
Title: 6-Shogaol and 6-gingerol, the pungent of ginger, inhibit TNF-alpha mediated downregulation of adiponectin expression via different mechanisms in 3T3-L1 adipocytes.
Journal: Biochemical and biophysical research communications 20080829
Title: Activation of endothelial cells to pathological status by down-regulation of connexin43.
Journal: Cardiovascular research 20080801
Title: Diesel exhaust particles induce oxidative stress, proinflammatory signaling, and P-glycoprotein up-regulation at the blood-brain barrier.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20080801
Title: Phosphorylation of Argonaute 2 at serine-387 facilitates its localization to processing bodies.
Journal: The Biochemical journal 20080801
Title: Crystal structure of the catalytic domain of the mitotic checkpoint kinase Mps1 in complex with SP600125.
Journal: The Journal of biological chemistry 20080801
Title: Characterization of early events involved in human dendritic cell maturation induced by sensitizers: cross talk between MAPK signalling pathways.
Journal: Toxicology and applied pharmacology 20080801
Title: The cannabinoid CP55,940 prolongs survival and improves locomotor activity in Drosophila melanogaster against paraquat: implications in Parkinson's disease.
Journal: Neuroscience research 20080801
Title: JNK supports survival in melanoma cells by controlling cell cycle arrest and apoptosis.
Journal: Pigment cell & melanoma research 20080801
Title: BDNF induces late-phase LTP of C-fiber evoked field potentials in rat spinal dorsal horn.
Journal: Experimental neurology 20080801
Title: Differential roles of p38-MAPK and JNKs in mediating early protection or apoptosis in the hyperthermic perfused amphibian heart.
Journal: The Journal of experimental biology 20080801
Title: Combination treatment with arsenic trioxide and sulindac enhances apoptotic cell death in lung cancer cells via activation of oxidative stress and mitogen-activated protein kinases.
Journal: Oncology reports 20080801
Title: P-glycoprotein down-regulates expression of breast cancer resistance protein in a drug-free state.
Journal: FEBS letters 20080723
Title: Piceatannol attenuates hydrogen-peroxide- and peroxynitrite-induced apoptosis of PC12 cells by blocking down-regulation of Bcl-XL and activation of JNK.
Journal: The Journal of nutritional biochemistry 20080701
Title: Dexamethasone-induced expression of endothelial mitogen-activated protein kinase phosphatase-1 involves activation of the transcription factors activator protein-1 and 3',5'-cyclic adenosine 5'-monophosphate response element-binding protein and the generation of reactive oxygen species.
Journal: Endocrinology 20080701
Title: JNK as a positive regulator of angiogenic potential in endothelial cells.
Journal: Cell biology international 20080701
Title: Cyclic AMP acts through Rap1 and JNK signaling to increase expression of cutaneous smooth muscle alpha2C-adrenoceptors.
Journal: American journal of physiology. Heart and circulatory physiology 20080701
Title: c-Jun NH2-terminal kinase 1 is a critical regulator for the development of gastric cancer in mice.
Journal: Cancer research 20080701
Title: Differential bortezomib sensitivity in head and neck cancer lines corresponds to proteasome, nuclear factor-kappaB and activator protein-1 related mechanisms.
Journal: Molecular cancer therapeutics 20080701
Title: Cytosolic accumulation of gammaH2AX is associated with tropomyosin-related kinase A-induced cell death in U2OS cells.
Journal: Experimental & molecular medicine 20080630
Title: Bcl-2 overexpression attenuates SP600125-induced apoptosis in human leukemia U937 cells.
Journal: Cancer letters 20080618
Title: The toxic effect of pyrrolizidine alkaloid clivorine on the human embryonic kidney 293 cells and its primary mechanism.
Journal: Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20080601
Title: Heme-oxygenase 1 gene expression is a marker for hexavalent chromium-induced stress and toxicity in human dermal fibroblasts.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20080601
Title: Prevotella intermedia induces matrix metalloproteinase-9 expression in human periodontal ligament cells.
Journal: FEMS microbiology letters 20080601
Title: Transforming growth factor {beta}1 induces epithelial-mesenchymal transition by activating the JNK-Smad3 pathway in rat peritoneal mesothelial cells.
Journal: Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis 20080601
Title: 25-hydroxycholesterol induces mitochondria-dependent apoptosis via activation of glycogen synthase kinase-3beta in PC12 cells.
Journal: Free radical research 20080601
Title: Pharmacological inhibitors of JNK and ERK kinases SP600125 and U0126 are not appropriate tools for studies of drug metabolism because they activate aryl hydrocarbon receptor.
Journal: General physiology and biophysics 20080601
Title: [Redox-dependent regulation of apoptosis as a function of intracellular reactive oxygen species in oxidative stress].
Journal: Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20080601
Title: Role of JNK translocation to mitochondria leading to inhibition of mitochondria bioenergetics in acetaminophen-induced liver injury.
Journal: The Journal of biological chemistry 20080516
Title: JNK- and IkappaB-dependent pathways regulate MCP-1 but not adiponectin release from artificially hypertrophied 3T3-L1 adipocytes preloaded with palmitate in vitro.
Journal: American journal of physiology. Endocrinology and metabolism 20080501
Title: Activation of peroxisome proliferator-activated receptor-gamma by curcumin blocks the signaling pathways for PDGF and EGF in hepatic stellate cells.
Journal: Laboratory investigation; a journal of technical methods and pathology 20080501
Title: Cruzipain and SP600125 induce p38 activation, alter NO/arginase balance and favor the survival of Trypanosoma cruzi in macrophages.
Journal: Acta tropica 20080501
Title: In vitro, inhibition of mitogen-activated protein kinase pathways protects against bupivacaine- and ropivacaine-induced neurotoxicity.
Journal: Anesthesia and analgesia 20080501
Title: The JNK signaling pathway is involved in sodium-selenite-induced apoptosis mediated by reactive oxygen in HepG2 cells.
Journal: Cancer biology & therapy 20080501
Title: Role of recombinant mitogen-activated protein kinases JNK and p38 in the regulation of apoptosis in blood mononuclear cells under conditions of oxidative stress in vitro.
Journal: Bulletin of experimental biology and medicine 20080501
Title: Involvement of oxidative stress-activated JNK signaling in the methamphetamine-induced cell death of human SH-SY5Y cells.
Journal: Toxicology 20080418
Title: Involvement of mitogen-activated protein kinases and NFkappaB in LPS-induced CD40 expression on human monocytic cells.
Journal: Toxicology and applied pharmacology 20080415
Title: Discovery, synthesis and biological evaluation of isoquinolones as novel and highly selective JNK inhibitors (1).
Journal: Bioorganic & medicinal chemistry 20080415
Title: MAPK and mTOR pathways are involved in cadmium-induced neuronal apoptosis.
Journal: Journal of neurochemistry 20080401
Title: Changes in the expression and dynamics of SHP-1 and SHP-2 during cerulein-induced acute pancreatitis in rats.
Journal: Biochimica et biophysica acta 20080401
Title: Distinct signaling pathways of microtubule inhibitors--vinblastine and Taxol induce JNK-dependent cell death but through AP-1-dependent and AP-1-independent mechanisms, respectively.
Journal: The FEBS journal 20080401
Title: Anti-fas activating antibody enhances trophoblast outgrowth on endometrial epithelial cells by induction of P38 MAPK/JNK-mediated apoptosis.
Journal: Placenta 20080401
Title: Differential roles for Nrf2 and AP-1 in upregulation of HO-1 expression by arsenite in murine embryonic fibroblasts.
Journal: Free radical research 20080401
Title: Distinct role of c-Jun N-terminal kinase isoforms in human neutrophil apoptosis regulated by tumor necrosis factor-alpha and granulocyte-macrophage colony-stimulating factor.
Journal: Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 20080401
Title: [Effect of staurosporine induced apoptosis of MCF7/GFP-Bax stable cell line on Bax translocation from cytosol into mitochondria].
Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20080401
Title: Lipopolysaccharide (LPS) of Porphyromonas gingivalis induces IL-1beta, TNF-alpha and IL-6 production by THP-1 cells in a way different from that of Escherichia coli LPS.
Journal: Innate immunity 20080401
Title: Inhibition of c-Jun N-terminal kinase sensitizes tumor cells to flavonoid-induced apoptosis through down-regulation of JunD.
Journal: Toxicology and applied pharmacology 20080315
Title: Cytotoxic effects of metal protoporphyrins in glioblastoma cells: roles of albumin, reactive oxygen species, and heme oxygenase-1.
Journal: Toxicology letters 20080315
Title: Resveratrol exerts antiproliferative activity and induces apoptosis in Waldenström's macroglobulinemia.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20080315
Title: Inhibitory effects of thunberginols A and B isolated from Hydrangeae Dulcis Folium on mRNA expression of cytokines and on activation of activator protein-1 in RBL-2H3 cells.
Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20080301
Title: The role of redox-sensitive transcription factors NF-kappaB and AP-1 in the modulation of the Cyp1a1 gene by mercury, lead, and copper.
Journal: Free radical biology & medicine 20080301
Title: Cytochrome P4502E1 sensitizes to tumor necrosis factor alpha-induced liver injury through activation of mitogen-activated protein kinases in mice.
Journal: Hepatology (Baltimore, Md.) 20080301
Title: Mycoplasma genitalium-derived lipid-associated membrane proteins induce activation of MAPKs, NF-kappaB and AP-1 in THP-1 cells.
Journal: FEMS immunology and medical microbiology 20080301
Title: Blockade of c-Jun N-terminal kinase activation abrogates hyperglycemia-induced yolk sac vasculopathy in vitro.
Journal: American journal of obstetrics and gynecology 20080301
Title: Role of mitogen-activated protein kinases in the iNOS production and cytokine secretion by Salmonella enterica serovar Typhimurium porins.
Journal: Cytokine 20080301
Title: Inhibition of Src and p38 MAP kinases suppresses the change of claudin expression induced on dedifferentiation of primary cultured parotid acinar cells.
Journal: American journal of physiology. Cell physiology 20080301
Title: p21 Waf1/Cip1 expression by curcumin in U-87MG human glioma cells: role of early growth response-1 expression.
Journal: Cancer research 20080301
Title: Stress-activated protein kinase inhibition to ameliorate lung ischemia reperfusion injury.
Journal: The Journal of thoracic and cardiovascular surgery 20080301
Title: MD-2 controls bacterial lipopolysaccharide hyporesponsiveness in human intestinal epithelial cells.
Journal: Life sciences 20080227
Title: SP600125 inhibits Kv channels through a JNK-independent pathway in cancer cells.
Journal: Biochemical and biophysical research communications 20080222
Title: The c-Jun N-terminal kinase pathway is critical for cell transformation by the latent membrane protein 1 of Epstein-Barr virus.
Journal: Virology 20080220
Title: c-jun-NH2JNK mediates invasive potential and EGFR activation by regulating the expression of HB-EGF in a urokinase-stimulated pathway.
Journal: Journal of cellular biochemistry 20080215
Title: Interleukin-1beta gene in orange-spotted grouper, Epinephelus coioides: molecular cloning, expression, biological activities and signal transduction.
Journal: Molecular immunology 20080201
Title: c-Jun N-terminal kinases trigger both degeneration and neurite outgrowth in primary hippocampal and cortical neurons.
Journal: Journal of neurochemistry 20080201
Title: Transient and sustained oxidative stress differentially activate the JNK1/2 pathway and apoptotic phenotype in H9c2 cells.
Journal: Molecular and cellular biochemistry 20080201
Title: JNK signaling pathway is required for bFGF-mediated surface cadherin downregulation on HUVEC.
Journal: Experimental cell research 20080201
Title: Internalization of Staphylococcus aureus by bovine endothelial cells is associated with the activity state of NF-kappaB and modulated by the pro-inflammatory cytokines TNF-alpha and IL-1beta.
Journal: Scandinavian journal of immunology 20080201
Title: Rapid and bi-directional regulation of AMPA receptor phosphorylation and trafficking by JNK.
Journal: The EMBO journal 20080123
Title: JNK inhibitor SP600125 is a partial agonist of human aryl hydrocarbon receptor and induces CYP1A1 and CYP1A2 genes in primary human hepatocytes.
Journal: Biochemical pharmacology 20080115
Title: Basal c-Jun N-terminal kinases promote mitotic progression through histone H3 phosphorylation.
Journal: Cell cycle (Georgetown, Tex.) 20080115
Title: 4-Hydroxynonenal self-limits fas-mediated DISC-independent apoptosis by promoting export of Daxx from the nucleus to the cytosol and its binding to Fas.
Journal: Biochemistry 20080108
Title: Human TAO kinase 1 induces apoptosis in SH-SY5Y cells.
Journal: Cell biology international 20080101
Title: c-Jun N-terminal kinase inhibitor II (SP600125) activates Mullerian inhibiting substance type II receptor-mediated signal transduction.
Journal: Endocrinology 20080101
Title: Specific inhibition of basal mitogen-activated protein kinases and phosphatidylinositol 3 kinase activities in leukemia cells: a possible therapeutic role for the kinase inhibitors.
Journal: Experimental hematology 20080101
Title: Inhibitors of c-Jun N-terminal kinases: JuNK no more?
Journal: Biochimica et biophysica acta 20080101
Title: Role of JNK-dependent serine phosphorylation of paxillin in migration of corneal epithelial cells during wound closure.
Journal: Investigative ophthalmology & visual science 20080101
Title: High glucose enhances lipopolysaccharide-stimulated CD14 expression in U937 mononuclear cells by increasing nuclear factor kappaB and AP-1 activities.
Journal: The Journal of endocrinology 20080101
Title: Involvement of ROS/ASMase/JNK signalling pathway in inhibiting UVA-induced apoptosis of HaCaT cells by polypeptide from Chlamys farreri.
Journal: Free radical research 20080101
Title: Inhibition of c-Jun N-terminal kinase pathway attenuates cerebral vasospasm after experimental subarachnoid hemorrhage through the suppression of apoptosis.
Journal: Acta neurochirurgica. Supplement 20080101
Title: Membrane initiated signaling by 1,25alpha-dihydroxyvitamin D3 in LNCaP prostate cancer cells.
Journal: Advances in experimental medicine and biology 20080101
Title: JNK pathway is involved in the inhibition of inflammatory target gene expression and NF-kappaB activation by melittin.
Journal: Journal of inflammation (London, England) 20080101
Title: Potentiation by platelet-derived growth factor-BB of FGF-2-stimulated VEGF release in osteoblasts.
Journal: Journal of bone and mineral metabolism 20080101
Title: NF-kappaB and AP-1 are key signaling pathways in the modulation of NAD(P)H:quinone oxidoreductase 1 gene by mercury, lead, and copper.
Journal: Journal of biochemical and molecular toxicology 20080101
Title: Function of Rho-kinase in prostaglandin D2-induced interleukin-6 synthesis in osteoblasts.
Journal: Prostaglandins, leukotrienes, and essential fatty acids 20080101
Title: Up-regulation of endothelin type B receptors in the human internal mammary artery in culture is dependent on protein kinase C and mitogen-activated kinase signaling pathways.
Journal: BMC cardiovascular disorders 20080101
Title: Retinoid acid inhibits IL-1-induced iNOS, COX-2 and chemokine production in human chondrocytes.
Journal: Immunological investigations 20080101
Title: Downregulation of CD147 expression alters cytoskeleton architecture and inhibits gelatinase production and SAPK pathway in human hepatocellular carcinoma cells.
Journal: Journal of experimental & clinical cancer research : CR 20080101
Title: Phorbol 12-myristate 13-acetate-activated protein kinase C increased migratory activity of subconjunctival fibroblasts via stress-activated protein kinase pathways.
Journal: Molecular vision 20071221
Title: A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases.
Journal: Proceedings of the National Academy of Sciences of the United States of America 20071218
Title: The selectivity of protein kinase inhibitors: a further update.
Journal: The Biochemical journal 20071215
Title: Nitric oxide dysregulates adipocytokine expression in 3T3-L1 adipocytes.
Journal: Biochemical and biophysical research communications 20071207
Title: MAPK inhibitors and pifithrin-alpha block cinnamaldehyde-induced apoptosis in human PLC/PRF/5 cells.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20071201
Title: Oridonin induced autophagy in human cervical carcinoma HeLa cells through Ras, JNK, and P38 regulation.
Journal: Journal of pharmacological sciences 20071201
Title: Histone H3 phosphorylation at serine 10 and serine 28 is mediated by p38 MAPK in rat hepatocytes exposed to ethanol and acetaldehyde.
Journal: European journal of pharmacology 20071114
Title: Berberine-induced LDLR up-regulation involves JNK pathway.
Journal: Biochemical and biophysical research communications 20071103
Title: EGCG-targeted p57/KIP2 reduces tumorigenicity of oral carcinoma cells: role of c-Jun N-terminal kinase.
Journal: Toxicology and applied pharmacology 20071101
Title: Inhibition of ERK and JNK decreases both osmosensitive taurine release and cell proliferation in glioma cells.
Journal: Neurochemical research 20071101
Title: Differential modulation of Alzheimer's disease amyloid beta-peptide accumulation by diverse classes of metal ligands.
Journal: The Biochemical journal 20071101
Title: Thimerosal-induced apoptosis in human SCM1 gastric cancer cells: activation of p38 MAP kinase and caspase-3 pathways without involvement of [Ca2+]i elevation.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20071101
Title: Geranylgeranylacetone, an inducer of the 70-kDa heat shock protein (HSP70), elicits unfolded protein response and coordinates cellular fate independently of HSP70.
Journal: Molecular pharmacology 20071101
Title: Antidepressants induce cellular insulin resistance by activation of IRS-1 kinases.
Journal: Molecular and cellular neurosciences 20071101
Title: Involvement of c-Jun NH2-terminal kinase and nitric oxide-mediated mitochondria-dependent intrinsic pathway signaling in cardiotoxin-induced muscle cell death: role of testosterone.
Journal: Apoptosis : an international journal on programmed cell death 20071101
Title: Mechanistic roles of leptin in osteogenic stimulation in thoracic ligament flavum cells.
Journal: The Journal of biological chemistry 20071012
Title: Long-acting kappa opioid antagonists disrupt receptor signaling and produce noncompetitive effects by activating c-Jun N-terminal kinase.
Journal: The Journal of biological chemistry 20071012
Title: Involvement of Na+/H+ exchangers in induction of cyclooxygenase-2 by vacuolar-type (H+)-ATPase inhibitors in RAW 264 cells.
Journal: FEBS letters 20071002
Title: Involvement of c-Jun N-terminal kinase in G2/M arrest and FasL-mediated apoptosis induced by a novel indoloquinoline derivative, IQDMA, in K562 cells.
Journal: Leukemia research 20071001
Title: Patterns of kinase activation induced by injury in the murine femoral artery.
Journal: The Journal of surgical research 20071001
Title: Inhibition of Jun NH2-terminal kinases suppresses the growth of experimental head and neck squamous cell carcinoma.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20071001
Title: Rapid and drastic induction of CYP3A4 mRNA expression via vitamin D receptor in human intestinal LS180 cells.
Journal: Drug metabolism and pharmacokinetics 20071001
Title: House dust mite induces expression of intercellular adhesion molecule-1 in EoL-1 human eosinophilic leukemic cells.
Journal: Journal of Korean medical science 20071001
Title: Tumor necrosis factor-related apoptosis-inducing ligand activates a lysosomal pathway of apoptosis that is regulated by Bcl-2 proteins.
Journal: The Journal of biological chemistry 20070928
Title: Manganese chloride stimulates rat microglia to release hydrogen peroxide.
Journal: Toxicology letters 20070910
Title: Penta-acetyl geniposide-induced apoptosis involving transcription of NGF/p75 via MAPK-mediated AP-1 activation in C6 glioma cells.
Journal: Toxicology 20070905
Title: IGF-I plus E2 induces proliferation via activation of ROS-dependent ERKs and JNKs in human breast carcinoma cells.
Journal: Journal of cellular physiology 20070901
Title: Opposing effects of Bad phosphorylation at two distinct sites by Akt1 and JNK1/2 on ischemic brain injury.
Journal: Cellular signalling 20070901
Title: Inhibition of c-Jun N-terminal kinase in the CA1 region of the dorsal hippocampus blocks extinction of inhibitory avoidance memory.
Journal: Behavioural pharmacology 20070901
Title: Ras pathway activation in malignant mesothelioma.
Journal: Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20070901
Title: Up-regulation of aldose reductase expression mediated by phosphatidylinositol 3-kinase/Akt and Nrf2 is involved in the protective effect of curcumin against oxidative damage.
Journal: Free radical biology & medicine 20070815
Title: Promotion of cancer cell migration: an insulin-like growth factor (IGF)-independent action of IGF-binding protein-6.
Journal: The Journal of biological chemistry 20070803
Title: Predominant activation of MAP kinases and pro-destructive/pro-inflammatory features by TNF alpha in early-passage synovial fibroblasts via TNF receptor-1: failure of p38 inhibition to suppress matrix metalloproteinase-1 in rheumatoid arthritis.
Journal: Annals of the rheumatic diseases 20070801
Title: Effect of JNK inhibition on cisplatin-induced renal damage.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20070801
Title: Beta-sitosterol-induced-apoptosis is mediated by the activation of ERK and the downregulation of Akt in MCA-102 murine fibrosarcoma cells.
Journal: International immunopharmacology 20070801
Title: Wogonin but not Nor-wogonin inhibits lipopolysaccharide and lipoteichoic acid-induced iNOS gene expression and NO production in macrophages.
Journal: International immunopharmacology 20070801
Title: Bee venom and melittin reduce proinflammatory mediators in lipopolysaccharide-stimulated BV2 microglia.
Journal: International immunopharmacology 20070801
Title: Interleukin-1beta modulates endogenous thyroid hormone receptor alpha gene transcription in liver cells.
Journal: The Journal of endocrinology 20070801
Title: Expression and function of mixed lineage kinases in dendritic cells.
Journal: International immunology 20070801
Title: [Effect of phosphorylated c-Jun expression on COX-2 expression in the substantia nigra of MPTP mouse model of subacute Parkinson disease].
Journal: Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20070801
Title: Activation of NADPH oxidase by transforming growth factor-beta in hepatocytes mediates up-regulation of epidermal growth factor receptor ligands through a nuclear factor-kappaB-dependent mechanism.
Journal: The Biochemical journal 20070715
Title: c-Jun N-terminal kinase signaling regulates events associated with both health and degeneration in motoneurons.
Journal: Neuroscience 20070713
Title: PAN-811 provides neuroprotection against glutamate toxicity by suppressing activation of JNK and p38 MAPK.
Journal: Neuroscience letters 20070705
Title: Critical role of c-jun (NH2) terminal kinase in paracetamol- induced acute liver failure.
Journal: Gut 20070701
Title: Humulone inhibits phorbol ester-induced COX-2 expression in mouse skin by blocking activation of NF-kappaB and AP-1: IkappaB kinase and c-Jun-N-terminal kinase as respective potential upstream targets.
Journal: Carcinogenesis 20070701
Title: Insulin protects liver cells from saturated fatty acid-induced apoptosis via inhibition of c-Jun NH2 terminal kinase activity.
Journal: Endocrinology 20070701
Title: Attenuation of ozone-induced airway inflammation and hyper-responsiveness by c-Jun NH2 terminal kinase inhibitor SP600125.
Journal: The Journal of pharmacology and experimental therapeutics 20070701
Title: TNFalpha induces apoptosis through JNK/Bax-dependent pathway in differentiated, but not naïve PC12 cells.
Journal: Cell cycle (Georgetown, Tex.) 20070615
Title: Simvastatin induces apoptosis in human breast cancer cells: p53 and estrogen receptor independent pathway requiring signalling through JNK.
Journal: Cancer letters 20070608
Title: Involvement of c-Jun N-terminal kinases activation in diabetic embryopathy.
Journal: Biochemical and biophysical research communications 20070608
Title: Induction of cyclooxygenase-2 expression by manganese in cultured astrocytes.
Journal: Neurochemistry international 20070601
Title: Pravastatin induces thrombomodulin expression in TNFalpha-treated human aortic endothelial cells by inhibiting Rac1 and Cdc42 translocation and activity.
Journal: Journal of cellular biochemistry 20070601
Title: Apoptotic effect of 3,4-dihydroxybenzoic acid on human gastric carcinoma cells involving JNK/p38 MAPK signaling activation.
Journal: International journal of cancer 20070601
Title: Indomethacin induces apoptosis in 786-O renal cell carcinoma cells by activating mitogen-activated protein kinases and AKT.
Journal: European journal of pharmacology 20070601
Title: Sequential treatment by ionizing radiation and sodium arsenite dramatically accelerates TRAIL-mediated apoptosis of human melanoma cells.
Journal: Cancer research 20070601
Title: Suppression of alloreactivity and allograft rejection by SP600125, a small molecule inhibitor of c-Jun N-terminal kinase.
Journal: Transplantation 20070527
Title: The nucleoside analog sangivamycin induces apoptotic cell death in breast carcinoma MCF7/adriamycin-resistant cells via protein kinase Cdelta and JNK activation.
Journal: The Journal of biological chemistry 20070518
Title: SP600125, a selective JNK inhibitor, protects ischemic renal injury via suppressing the extrinsic pathways of apoptosis.
Journal: Life sciences 20070508
Title: Thrombin-induced ischemic tolerance is prevented by inhibiting c-jun N-terminal kinase.
Journal: Brain research 20070507
Title: c-Jun N-terminal kinase mediates AML1-ETO protein-induced connexin-43 expression.
Journal: Biochemical and biophysical research communications 20070504
Title: Induced secretion of insulin-like growth factor binding protein-1 (IGFBP-1) in human hepatoma cell HepG2 by rubratoxin B.
Journal: Archives of toxicology 20070501
Title: Inhibitory effect of TNF-alpha on the intestinal absorption of galactose.
Journal: Journal of cellular biochemistry 20070501
Title: P38 and ERK mitogen-activated protein kinases mediate acrolein-induced apoptosis in Chinese hamster ovary cells.
Journal: Cellular signalling 20070501
Title: c-Jun N-terminal kinase mediates hydrogen peroxide-induced cell death via sustained poly(ADP-ribose) polymerase-1 activation.
Journal: Cell death and differentiation 20070501
Title: Post-transcriptional regulation of human inducible nitric-oxide synthase expression by the Jun N-terminal kinase.
Journal: Molecular pharmacology 20070501
Title: The interruption of the PDGF and EGF signaling pathways by curcumin stimulates gene expression of PPARgamma in rat activated hepatic stellate cell in vitro.
Journal: Laboratory investigation; a journal of technical methods and pathology 20070501
Title: IKappaB-kinase/nuclear factor-kappaB signaling prevents thermal injury-induced gut damage by inhibiting c-Jun NH2-terminal kinase activation.
Journal: Critical care medicine 20070501
Title: Celecoxib decreases fatty acid synthase expression via down-regulation of c-Jun N-terminal kinase-1.
Journal: Experimental biology and medicine (Maywood, N.J.) 20070501
Title: [CD147 stimulates the angiogenesis in rheumatoid synovium via the activation of vascular endothelial growth factor].
Journal: Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology 20070501
Title: Hydroquinone, a reactive metabolite of benzene, reduces macrophage-mediated immune responses.
Journal: Molecules and cells 20070430
Title: Kinetic characterization of human JNK2alpha2 reaction mechanism using substrate competitive inhibitors.
Journal: Biochemistry 20070424
Title: (-)-Epigallocatechin gallate suppresses endothelin-1-induced interleukin-6 synthesis in osteoblasts: inhibition of p44/p42 MAP kinase activation.
Journal: FEBS letters 20070403
Title: Differential regulation of indoleamine 2,3-dioxygenase by lipopolysaccharide and interferon gamma in murine bone marrow derived dendritic cells.
Journal: FEBS letters 20070403
Title: Curcumin attenuates glutamate-induced HT22 cell death by suppressing MAP kinase signaling.
Journal: Molecular and cellular biochemistry 20070401
Title: Inhibition of JNK activation prolongs survival after smoke inhalation from fires.
Journal: American journal of physiology. Lung cellular and molecular physiology 20070401
Title: TRPV6 mediates capsaicin-induced apoptosis in gastric cancer cells--Mechanisms behind a possible new 'hot' cancer treatment.
Journal: Biochimica et biophysica acta 20070401
Title: Interleukin-1 mediates thermal injury-induced lung damage through C-Jun NH2-terminal kinase signaling.
Journal: Critical care medicine 20070401
Title: Interleukin-1 in thermal injury: what is next?
Journal: Critical care medicine 20070401
Title: Flashlamp pulsed-dye laser suppressed TGF-beta1 expression and proliferation in cultured keloid fibroblasts is mediated by MAPK pathway.
Journal: Lasers in surgery and medicine 20070401
Title: c-Jun N-terminal kinase inhibitor SP600125 modulates the period of mammalian circadian rhythms.
Journal: Neuroscience 20070330
Title: Bakuchiol-induced caspase-3-dependent apoptosis occurs through c-Jun NH2-terminal kinase-mediated mitochondrial translocation of Bax in rat liver myofibroblasts.
Journal: European journal of pharmacology 20070322
Title: An inhibitor of c-Jun NH2-terminal kinase, SP600125, protects mice from D-galactosamine/lipopolysaccharide-induced hepatic failure by modulating BH3-only proteins.
Journal: Life sciences 20070313
Title: Hydrogen peroxide stimulates macrophages and monocytes to actively release HMGB1.
Journal: Journal of leukocyte biology 20070301
Title: Negative regulation by p70 S6 kinase of FGF-2-stimulated VEGF release through stress-activated protein kinase/c-Jun N-terminal kinase in osteoblasts.
Journal: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20070301
Title: REIC/Dkk-3 as a potential gene therapeutic agent against human testicular cancer.
Journal: International journal of molecular medicine 20070301
Title: Suppression of endoplasmic reticulum stress-induced caspase activation and cell death by the overexpression of Bcl-xL or Bcl-2.
Journal: Journal of biochemistry 20070301
Title: Bone morphogenetic protein-4 abrogates lumen formation by mammary epithelial cells and promotes invasive growth.
Journal: Biochemical and biophysical research communications 20070216
Title: p38MAPK activation is involved in androgen-independent proliferation of human prostate cancer cells by regulating IL-6 secretion.
Journal: Biochemical and biophysical research communications 20070216
Title: Docetaxel-induced apoptosis of human melanoma is mediated by activation of c-Jun NH2-terminal kinase and inhibited by the mitogen-activated protein kinase extracellular signal-regulated kinase 1/2 pathway.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20070215
Title: Estrogen regulates Bcl-w and Bim expression: role in protection against beta-amyloid peptide-induced neuronal death.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20070207
Title: Inhibitory effect of obovatol on nitric oxide production and activation of NF-kappaB/MAP kinases in lipopolysaccharide-treated RAW 264.7cells.
Journal: European journal of pharmacology 20070205
Title: Inhibition of JNK increases survival of transplanted dopamine neurons in Parkinsonian rats.
Journal: Cell death and differentiation 20070201
Title: Inhibition of c-Jun N-terminal kinase rescues influenza epitope-specific human cytolytic T lymphocytes from activation-induced cell death.
Journal: Journal of leukocyte biology 20070201
Title: A novel pathway for transcriptional regulation of alpha-synuclein.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20070201
Title: The role of chrysin and the ah receptor in induction of the human UGT1A1 gene in vitro and in transgenic UGT1 mice.
Journal: Hepatology (Baltimore, Md.) 20070201
Title: Macrophage migration inhibitory factor induces MMP-9 expression in macrophages via the MEK-ERK MAP kinase pathway.
Journal: Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 20070201
Title: Complementary effects of HDAC inhibitor 4-PB on gap junction communication and cellular export mechanisms support restoration of chemosensitivity of PDAC cells.
Journal: British journal of cancer 20070115
Title: Neurotoxicity assessment using zebrafish.
Journal: Journal of pharmacological and toxicological methods 20070101
Title: Elevated gadd153/chop expression during resveratrol-induced apoptosis in human colon cancer cells.
Journal: Biochemical pharmacology 20070101
Title: Dopaminergic and adrenergic toxicities on SK-N-MC human neuroblastoma cells are mediated through G protein signaling and oxidative stress.
Journal: Apoptosis : an international journal on programmed cell death 20070101
Title: JNK1 contributes to metabotropic glutamate receptor-dependent long-term depression and short-term synaptic plasticity in the mice area hippocampal CA1.
Journal: The European journal of neuroscience 20070101
Title: Polyphenols downregulate PAI-1 gene expression in cultured human coronary artery endothelial cells: molecular contributor to cardiovascular protection.
Journal: Thrombosis research 20070101
Title: Involvement of glycogen synthase kinase-3beta in palmitate-induced human umbilical vein endothelial cell apoptosis.
Journal: Journal of vascular research 20070101
Title: c-Jun N-terminal kinase (JNK) cooperates with Gsk3beta to regulate Dishevelled-mediated microtubule stability.
Journal: BMC cell biology 20070101
Title: The c-Jun-N-terminal kinase is involved in the neurotoxic effect of azaspiracid-1.
Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20070101
Title: UV-B-induced signaling events leading to enhanced-production of catharanthine in Catharanthus roseus cell suspension cultures.
Journal: BMC plant biology 20070101
Title: Ca2+ stimulates COX-2 expression through calcium-sensing receptor in fibroblasts.
Journal: Biochemical and biophysical research communications 20061229
Title: Involvement of mitogen-activated protein kinases and protein kinase C in regulation of antioxidant response element activity in human keratinocytes.
Journal: Cancer letters 20061208
Title: Involvement of MAP kinases in lipopolysaccharide-induced histamine production in RAW 264 cells.
Journal: Life sciences 20061203
Title: Upregulation of TRAIL-R2 is not involved in HDACi mediated sensitization to TRAIL-induced apoptosis.
Journal: Cell death and differentiation 20061201
Title: Involvement of p38 MAP kinase and Smad3 in TGF-beta-mediated mast cell functions.
Journal: Cellular signalling 20061201
Title: Pharmacologic inhibitors of extracellular signal-regulated kinase (ERKs) and c-Jun NH(2)-terminal kinase (JNK) decrease glutathione content and sensitize human promonocytic leukemia cells to arsenic trioxide-induced apoptosis.
Journal: Journal of cellular physiology 20061201
Title: The c-Jun-N-terminal-Kinase inhibitor SP600125 enhances the butyrate derivative D1-induced apoptosis via caspase 8 activation in Kasumi 1 t(8;21) acute myeloid leukaemia cells.
Journal: British journal of haematology 20061201
Title: Activation-induced cell death of human melanoma specific cytotoxic T lymphocytes is mediated by apoptosis-inducing factor.
Journal: European journal of immunology 20061201
Title: JunD is a profibrogenic transcription factor regulated by Jun N-terminal kinase-independent phosphorylation.
Journal: Hepatology (Baltimore, Md.) 20061201
Title: Buthionine sulfoximine enhancement of arsenic trioxide-induced apoptosis in leukemia and lymphoma cells is mediated via activation of c-Jun NH2-terminal kinase and up-regulation of death receptors.
Journal: Cancer research 20061201
Title: Interleukin-1beta up-regulates inducible nitric oxide by way of phosphoinositide 3-kinase-dependent in a cochlear cell model.
Journal: The Laryngoscope 20061201
Title: In vitro evidence for role of ERK, p38, and JNK in exocrine pancreatic cytokine production.
Journal: Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 20061201
Title: [Amelioration of insulin resistance after scald by c-Jun N-terminal kinase inhibitor in rat].
Journal: Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns 20061201
Title: [The role of MAPK/ERK1/2 signaling pathway in aldosterone stimulated transforming growth factor-beta1 synthesis in renal tubular epithelial cells].
Journal: Zhonghua yi xue za zhi 20061128
Title: Emodin inhibits TNF alpha-induced MMP-1 expression through suppression of activator protein-1 (AP-1).
Journal: Life sciences 20061125
Title: Leflunomide or A77 1726 protect from acetaminophen-induced cell injury through inhibition of JNK-mediated mitochondrial permeability transition in immortalized human hepatocytes.
Journal: Toxicology and applied pharmacology 20061115
Title: Acetylcholinesterase expression mediated by c-Jun-NH2-terminal kinase pathway during anticancer drug-induced apoptosis.
Journal: Oncogene 20061109
Title: Silibinin activates p53-caspase 2 pathway and causes caspase-mediated cleavage of Cip1/p21 in apoptosis induction in bladder transitional-cell papilloma RT4 cells: evidence for a regulatory loop between p53 and caspase 2.
Journal: Carcinogenesis 20061101
Title: Nitric oxide production by the vacuolar-type (H+)-ATPase inhibitors bafilomycin A1 and concanamycin A and its possible role in apoptosis in RAW 264.7 cells.
Journal: The Journal of pharmacology and experimental therapeutics 20061101
Title: Activation of mitogen-activated protein kinases is essential for hydrogen peroxide -induced apoptosis in retinal pigment epithelial cells.
Journal: Apoptosis : an international journal on programmed cell death 20061101
Title: Histamine differentially interacts with tumor necrosis factor-alpha and thrombin in endothelial tissue factor induction: the role of c-Jun NH2-terminal kinase.
Journal: Journal of thrombosis and haemostasis : JTH 20061101
Title: P38 MAPK protects against TNF-alpha-provoked apoptosis in LNCaP prostatic cancer cells.
Journal: Apoptosis : an international journal on programmed cell death 20061101
Title: Targeted mutation of serine 697 in the Ret tyrosine kinase causes migration defect of enteric neural crest cells.
Journal: Development (Cambridge, England) 20061101
Title: Disruption of JNK2 decreases the cytokine response to Plasmodium falciparum glycosylphosphatidylinositol in vitro and confers protection in a cerebral malaria model.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20061101
Title: Diabetes-induced mechanical hyperalgesia involves spinal mitogen-activated protein kinase activation in neurons and microglia via N-methyl-D-aspartate-dependent mechanisms.
Journal: Molecular pharmacology 20061001
Title: Jak3- and JNK-dependent vascular endothelial growth factor expression in cutaneous T-cell lymphoma.
Journal: Leukemia 20061001
Title: Regulation by Jun N-terminal kinase/stress activated protein kinase of cytokine expression in Mycobacterium avium subsp paratuberculosis-infected bovine monocytes.
Journal: American journal of veterinary research 20061001
Title: Transcriptional regulation of the human Sia-alpha2,3-Gal-beta1,4-GlcNAc-R:alpha2,8-sialyltransferase (hST8Sia III) by retinoic acid in human glioblastoma tumor cell line.
Journal: Biochimica et biophysica acta 20061001
Title: Induction of apoptosis and cell cycle arrest by a specific c-Jun NH2-terminal kinase (JNK) inhibitor, SP-600125, in gastrointestinal cancers.
Journal: Cancer letters 20060928
Title: Differential transcriptional responses of keloid and normal keratinocytes to serum stimulation.
Journal: The Journal of surgical research 20060901
Title: Immune regulation of 25-hydroxyvitamin D-1alpha-hydroxylase in human monocytic THP1 cells: mechanisms of interferon-gamma-mediated induction.
Journal: The Journal of clinical endocrinology and metabolism 20060901
Title: p38 MAPK downregulates phosphorylation of Bad in doxorubicin-induced endothelial apoptosis.
Journal: Biochemical and biophysical research communications 20060901
Title: Growth suppression of human mast cells expressing constitutively active c-kit receptors by JNK inhibitor SP600125.
Journal: Genes to cells : devoted to molecular & cellular mechanisms 20060901
Title: PPARgamma phosphorylation mediated by JNK MAPK: a potential role in macrophage-derived foam cell formation.
Journal: Acta pharmacologica Sinica 20060901
Title: Increase in production of matrix metalloproteinase 13 by human articular chondrocytes due to stimulation with S100A4: Role of the receptor for advanced glycation end products.
Journal: Arthritis and rheumatism 20060901
Title: SP600125, a selective JNK inhibitor, aggravates hepatic ischemia-reperfusion injury.
Journal: Experimental & molecular medicine 20060831
Title: Involvement of JNK-initiated p53 accumulation and phosphorylation of p53 in pseudolaric acid B induced cell death.
Journal: Experimental & molecular medicine 20060831
Title: Acquired tolerance in cadmium-adapted lung epithelial cells: roles of the c-Jun N-terminal kinase signaling pathway and basal level of metallothionein.
Journal: Toxicology and applied pharmacology 20060815
Title: atRA-induced apoptosis of mouse embryonic palate mesenchymal cells involves activation of MAPK pathway.
Journal: Toxicology and applied pharmacology 20060815
Title: TNFalpha and GM-CSF-induced activation of the CAEV promoter is independent of AP-1.
Journal: Virology 20060815
Title: Ligustilide inhibits vascular smooth muscle cells proliferation.
Journal: European journal of pharmacology 20060807
Title: Upregulation of endothelial heme oxygenase-1 expression through the activation of the JNK pathway by sublethal concentrations of acrolein.
Journal: Toxicology and applied pharmacology 20060801
Title: Pharmacological and molecular characterization of the mechanisms involved in prostaglandin E2-induced mouse paw edema.
Journal: The Journal of pharmacology and experimental therapeutics 20060801
Title: Copper-induced stimulation of extracellular signal-regulated kinase in trout hepatocytes: the role of reactive oxygen species, Ca2+, and cell energetics and the impact of extracellular signal-regulated kinase signaling on apoptosis and necrosis.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20060801
Title: Low concentrations of paraquat induces early activation of extracellular signal-regulated kinase 1/2, protein kinase B, and c-Jun N-terminal kinase 1/2 pathways: role of c-Jun N-terminal kinase in paraquat-induced cell death.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20060801
Title: Esculetin induces mitochondria-mediated apoptosis in 3T3-L1 adipocytes.
Journal: Apoptosis : an international journal on programmed cell death 20060801
Title: c-Jun N-terminal kinase upregulation as a key event in the proapoptotic interaction between transforming growth factor-beta1 and 4-hydroxynonenal in colon mucosa.
Journal: Free radical biology & medicine 20060801
Title: Prostaglandin D2 induces the phosphorylation of HSP27 in osteoblasts: function of the MAP kinase superfamily.
Journal: Prostaglandins, leukotrienes, and essential fatty acids 20060801
Title: c-Jun N-terminal kinase negatively regulates dsRNA and RSV induction of tumor necrosis factor- alpha transcription in human epithelial cells.
Journal: Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 20060801
Title: p44/42 MAP kinase and c-Jun N-terminal kinase contribute to the up-regulation of caspase-3 in manganese-induced apoptosis in PC12 cells.
Journal: Brain research 20060712
Title: Manganese modulates pro-inflammatory gene expression in activated glia.
Journal: Neurochemistry international 20060701
Title: Nuclear factor-kappa B-independent anti-inflammatory action of salicylate in human endothelial cells: induction of heme oxygenase-1 by the c-jun N-terminal kinase/activator protein-1 pathway.
Journal: The Journal of pharmacology and experimental therapeutics 20060701
Title: Essential role of c-Jun-NH2-terminal kinase on synergy induction of apoptosis by TRAIL plus ADM in ADM resistant MCF-7/ADM cells.
Journal: Apoptosis : an international journal on programmed cell death 20060701
Title: Perfusion-culture-based secreted bioluminescence reporter assay in living cells.
Journal: Analytical biochemistry 20060701
Title: Map kinase c-JUN N-terminal kinase mediates PMMA induction of osteoclasts.
Journal: Journal of orthopaedic research : official publication of the Orthopaedic Research Society 20060701
Title: c-Jun N-terminal kinase plays a major role in murine acetaminophen hepatotoxicity.
Journal: Gastroenterology 20060701
Title: Degradation of the Alzheimer disease amyloid beta-peptide by metal-dependent up-regulation of metalloprotease activity.
Journal: The Journal of biological chemistry 20060630
Title: Ionizing radiation induces apoptosis and inhibits neuronal differentiation in rat neural stem cells via the c-Jun NH2-terminal kinase (JNK) pathway.
Journal: Oncogene 20060622
Title: Synaptogenesis regulates axotomy-induced activation of c-Jun-activator protein-1 transcription.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20060614
Title: Mitogen-activated protein kinases mediate arsenic-induced down-regulation of survivin in human lung adenocarcinoma cells.
Journal: Archives of toxicology 20060601
Title: JNK inhibitor SP600125 reduces COX-2 expression by attenuating mRNA in activated murine J774 macrophages.
Journal: International immunopharmacology 20060601
Title: Interplay between epidermal growth factor receptor and Janus kinase 3 regulates polychlorinated biphenyl-induced matrix metalloproteinase-3 expression and transendothelial migration of tumor cells.
Journal: Molecular cancer research : MCR 20060601
Title: Dracorhodin perchlorate induces apoptosis in HL-60 cells.
Journal: Journal of Asian natural products research 20060601
Title: Neuroprotection against ischemic brain injury by SP600125 via suppressing the extrinsic and intrinsic pathways of apoptosis.
Journal: Brain research 20060530
Title: Two distinct steps of Bak regulation during apoptotic stress signaling: different roles of MEKK1 and JNK1.
Journal: Experimental cell research 20060515
Title: Regression of aortic aneurysms through pharmacologic therapy?
Journal: The New England journal of medicine 20060511
Title: Inhibition of the ERK/MAP kinase pathway attenuates heme oxygenase-1 expression and heme-mediated neuronal injury.
Journal: Neuroscience letters 20060508
Title: N-(4-hydroxyphenyl)retinamide-induced apoptosis triggered by reactive oxygen species is mediated by activation of MAPKs in head and neck squamous carcinoma cells.
Journal: Oncogene 20060504
Title: Oxidative stress and mitogen-activated protein kinase phosphorylation mediate ammonia-induced cell swelling and glutamate uptake inhibition in cultured astrocytes.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20060503
Title: Involvement of p38 MAPK and Nrf2 in phenolic acid-induced P-form phenol sulfotransferase expression in human hepatoma HepG2 cells.
Journal: Carcinogenesis 20060501
Title: Superoxide anions and hydrogen peroxide induce hepatocyte death by different mechanisms: involvement of JNK and ERK MAP kinases.
Journal: Journal of hepatology 20060501
Title: Zn2+-induced IL-8 expression involves AP-1, JNK, and ERK activities in human airway epithelial cells.
Journal: American journal of physiology. Lung cellular and molecular physiology 20060501
Title: Manganese induces inducible nitric oxide synthase (iNOS) expression via activation of both MAP kinase and PI3K/Akt pathways in BV2 microglial cells.
Journal: Neuroscience letters 20060501
Title: Iron released by sodium nitroprusside contributes to heme oxygenase-1 induction via the cAMP-protein kinase A-mitogen-activated protein kinase pathway in RAW 264.7 cells.
Journal: Molecular pharmacology 20060501
Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.
Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
Title: Roles for phosphoinositide 3-kinases, Bruton's tyrosine kinase, and Jun kinases in B lymphocyte chemotaxis and homing.
Journal: European journal of immunology 20060501
Title: The specific JNK inhibitor SP600125 targets tumour necrosis factor-alpha production and epithelial cell apoptosis in acute murine colitis.
Journal: Immunology 20060501
Title: MAP kinase regulation of IP10/CXCL10 chemokine gene expression in microglial cells.
Journal: Brain research 20060501
Title: The novel antioxidant 3-O-caffeoyl-1-methylquinic acid induces Nrf2-dependent phase II detoxifying genes and alters intracellular glutathione redox.
Journal: Free radical biology & medicine 20060415
Title: The effects of ZD1839 (Iressa), a highly selective EGFR tyrosine kinase inhibitor, as a radiosensitiser in bile duct carcinoma cell lines.
Journal: International journal of oncology 20060401
Title: Involvement of protein kinases on the upregulation of endothelin receptors in rat basilar and mesenteric arteries.
Journal: Experimental biology and medicine (Maywood, N.J.) 20060401
Title: Differential involvement of nuclear factor-kappaB and activator protein-1 pathways in the interleukin-1beta-mediated decrease of deiodinase type 1 and thyroid hormone receptor beta1 mRNA.
Journal: The Journal of endocrinology 20060401
Title: S-adenosyl-methionine decreases ethanol-induced apoptosis in primary hepatocyte cultures by a c-Jun N-terminal kinase activity-independent mechanism.
Journal: World journal of gastroenterology 20060328
Title: Regulation of cardiotrophin-1 expression in mouse embryonic stem cells by HIF-1alpha and intracellular reactive oxygen species.
Journal: Journal of cell science 20060315
Title: Glycine-extended gastrin inhibits apoptosis in colon cancer cells via separate activation of Akt and JNK pathways.
Journal: Molecular and cellular endocrinology 20060309
Title: Interleukin-1 beta up-regulates tissue inhibitor of matrix metalloproteinase-1 mRNA and phosphorylation of c-jun N-terminal kinase and p38 in hepatic stellate cells.
Journal: World journal of gastroenterology 20060307
Title: Resveratrol protects against 4-hydroxynonenal-induced apoptosis by blocking JNK and c-JUN/AP-1 signaling.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20060301
Title: Opposing effect of p38 MAP kinase and JNK inhibitors on the development of heart failure in the cardiomyopathic hamster.
Journal: Cardiovascular research 20060301
Title: Proteasome blockade exerts an antifibrotic activity by coordinately down-regulating type I collagen and tissue inhibitor of metalloproteinase-1 and up-regulating metalloproteinase-1 production in human dermal fibroblasts.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20060301
Title: Pro-inflammatory signaling by Jun-N-terminal kinase in inflammatory bowel disease.
Journal: International journal of molecular medicine 20060301
Title: Selective pharmacologic inhibition of c-Jun NH2-terminal kinase radiosensitizes thyroid anaplastic cancer cell lines via induction of terminal growth arrest.
Journal: Thyroid : official journal of the American Thyroid Association 20060301
Title: FADD phosphorylation is critical for cell cycle regulation in breast cancer cells.
Journal: British journal of cancer 20060227
Title: Inhibition of apolipoprotein AI gene expression by tumor necrosis factor alpha: roles for MEK/ERK and JNK signaling.
Journal: Biochemistry 20060221
Title: Matrix metalloproteinase-2 and -9 are induced differently by doxorubicin in H9c2 cells: The role of MAP kinases and NAD(P)H oxidase.
Journal: Cardiovascular research 20060215
Title: As2O3-induced c-Src/EGFR/ERK signaling is via Sp1 binding sites to stimulate p21WAF1/CIP1 expression in human epidermoid carcinoma A431 cells.
Journal: Cellular signalling 20060201
Title: A role for FXR and human FGF-19 in the repression of paraoxonase-1 gene expression by bile acids.
Journal: Journal of lipid research 20060201
Title: Shiga toxin 1-induced cytokine production is mediated by MAP kinase pathways and translation initiation factor eIF4E in the macrophage-like THP-1 cell line.
Journal: Journal of leukocyte biology 20060201
Title: Involvement of COX-2 in VEGF-induced angiogenesis via P38 and JNK pathways in vascular endothelial cells.
Journal: Cardiovascular research 20060201
Title: The roles of Akt and MAPK family members in silymarin's protection against UV-induced A375-S2 cell apoptosis.
Journal: International immunopharmacology 20060201
Title: Porphyromonas gingivalis-related cardiac cell apoptosis was majorly co-activated by p38 and extracellular signal-regulated kinase pathways.
Journal: Journal of periodontal research 20060201
Title: Transcriptional repression of telomerase RNA gene expression by c-Jun-NH2-kinase and Sp1/Sp3.
Journal: Cancer research 20060201
Title: c-Jun N-terminal kinase contributes to norepinephrine-induced contraction through phosphorylation of caldesmon in rat aortic smooth muscle.
Journal: Journal of pharmacological sciences 20060201
Title: Brain ischemia/reperfusion-induced expression of DP5 and its interaction with Bcl-2, thus freeing Bax from Bcl-2/Bax dimmers are mediated by c-Jun N-terminal kinase (JNK) pathway.
Journal: Neuroscience letters 20060130
Title: Cepharanthine triggers apoptosis in a human hepatocellular carcinoma cell line (HuH-7) through the activation of JNK1/2 and the downregulation of Akt.
Journal: FEBS letters 20060123
Title: NAD(P)H oxidase-derived reactive oxygen species regulate angiotensin-II induced adventitial fibroblast phenotypic differentiation.
Journal: Biochemical and biophysical research communications 20060106
Title: Opposite effect of ERK1/2 and JNK on p53-independent p21WAF1/CIP1 activation involved in the arsenic trioxide-induced human epidermoid carcinoma A431 cellular cytotoxicity.
Journal: Journal of biomedical science 20060101
Title: c-Jun NH2-terminal kinase mediates interleukin-1beta-induced inhibition of lacrimal gland secretion.
Journal: Journal of neurochemistry 20060101
Title: c-Jun N-terminal kinase inhibition and alpha-tocopherol protect midbrain dopaminergic neurons from interferon-gamma/lipopolysaccharide-induced injury without affecting nitric oxide production.
Journal: Journal of neuroscience research 20060101
Title: Differential regulation of c-jun and CREB by acrolein and 4-hydroxynonenal.
Journal: Free radical biology & medicine 20060101
Title: NF-kappaB and activator protein 1 response elements and the role of histone modifications in IL-1beta-induced TGF-beta1 gene transcription.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20060101
Title: Inhibition of mitogen-activated protein kinase signalling by Bacillus anthracis lethal toxin causes destabilization of interleukin-8 mRNA.
Journal: Cellular microbiology 20060101
Title: Activation of c-Jun N-terminal kinase (JNK) signalling in experimentally induced gastric lesions in rats.
Journal: Clinical and experimental immunology 20060101
Title: Thermal injury-induced peroxynitrite production and pulmonary inducible nitric oxide synthase expression depend on JNK/AP-1 signaling.
Journal: Critical care medicine 20060101
Title: [Effects of sp600125 on proliferation and protein expression of bcl-2 and c-myc in hepatic stellate cells].
Journal: Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20060101
Title: Trimidox induces apoptosis via cytochrome c release in NALM-6 human B cell leukaemia cells.
Journal: Basic & clinical pharmacology & toxicology 20060101
Title: Inhibition of p38 mitogen-activated protein kinase enhances c-Jun N-terminal kinase activity: implication in inducible nitric oxide synthase expression.
Journal: BMC pharmacology 20060101
Title: Inhibition of UVA-induced c-Jun N-terminal kinase activity results in caspase-dependent apoptosis in human keratinocytes.
Journal: Photochemistry and photobiology 20060101
Title: C-Jun N-terminal kinase (JNK) regulation of iNOS expression in glial cells: predominant role of JNK1 isoform.
Journal: Antioxidants & redox signaling 20060101
Title: Streptococcus pneumoniae induced c-Jun-N-terminal kinase- and AP-1 -dependent IL-8 release by lung epithelial BEAS-2B cells.
Journal: Respiratory research 20060101
Title: Macrophage migration inhibitory factor: a mediator of matrix metalloproteinase-2 production in rheumatoid arthritis.
Journal: Arthritis research & therapy 20060101
Title: JAK inhibitors AG-490 and WHI-P154 decrease IFN-gamma-induced iNOS expression and NO production in macrophages.
Journal: Mediators of inflammation 20060101
Title: Up-regulation of P-glycoprotein expression by catalase via JNK activation in HepG2 cells.
Journal: Redox report : communications in free radical research 20060101
Title: Bortezomib sensitizes pancreatic cancer cells to endoplasmic reticulum stress-mediated apoptosis.
Journal: Cancer research 20051215
Title: Synergistic activation of JNK/SAPK induced by TNF-alpha and IFN-gamma: apoptosis of pancreatic beta-cells via the p53 and ROS pathway.
Journal: Cellular signalling 20051201
Title: Gaseous nitrogen oxide repressed benzo[a]pyrene-induced human lung fibroblast cell apoptosis via inhibiting JNK1 signals.
Journal: Archives of toxicology 20051201
Title: Involvement of histone acetyltransferase (HAT) in ethanol-induced acetylation of histone H3 in hepatocytes: potential mechanism for gene expression.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20051201
Title: KGF induces lipogenic genes through a PI3K and JNK/SREBP-1 pathway in H292 cells.
Journal: Journal of lipid research 20051201
Title: Regression of abdominal aortic aneurysm by inhibition of c-Jun N-terminal kinase.
Journal: Nature medicine 20051201
Title: Aneurysm treatments expand.
Journal: Nature medicine 20051201
Title: X-linked inhibitor of apoptosis (XIAP) inhibits c-Jun N-terminal kinase 1 (JNK1) activation by transforming growth factor beta1 (TGF-beta1) through ubiquitin-mediated proteosomal degradation of the TGF-beta1-activated kinase 1 (TAK1).
Journal: The Journal of biological chemistry 20051118
Title: Hsp70 inhibits heat-induced apoptosis upstream of mitochondria by preventing Bax translocation.
Journal: The Journal of biological chemistry 20051118
Title: Arsenite enhances tumor necrosis factor-alpha-induced expression of vascular cell adhesion molecule-1.
Journal: Toxicology and applied pharmacology 20051115
Title: The role of p38 MAP kinase and c-Jun N-terminal protein kinase signaling in the differentiation and apoptosis of immortalized neural stem cells.
Journal: Mutation research 20051111
Title: Leukotriene B4 receptor inhibitor LY293111 induces cell cycle arrest and apoptosis in human anaplastic large-cell lymphoma cells via JNK phosphorylation.
Journal: Leukemia 20051101
Title: Regulation of B7.1 costimulatory molecule is mediated by the IFN regulatory factor-7 through the activation of JNK in lipopolysaccharide-stimulated human monocytic cells.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20051101
Title: Agents targeting c-Jun N-terminal kinase pathway as potential neuroprotectants.
Journal: Expert opinion on investigational drugs 20051101
Title: [Role of MAPK in the migration of human coronary artery smooth muscle cell into three-dimensional fibrin gel].
Journal: Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 20051101
Title: Inhibitors of mitogen-activated protein kinases downregulate COX-2 expression in human chondrocytes.
Journal: Mediators of inflammation 20051024
Title: The role of p-c-Jun in survival and outgrowth of developing sensory neurons.
Journal: Neuroreport 20051017
Title: Arsenic trioxide induces Hsp70 expression via reactive oxygen species and JNK pathway in MDA231 cells.
Journal: Life sciences 20051014
Title: Regulation of cAMP-induced arylalkylamine N-acetyltransferase, Period1, and MKP-1 gene expression by mitogen-activated protein kinases in the rat pineal gland.
Journal: Brain research. Molecular brain research 20051003
Title: Inhibition of iNOS gene expression by quercetin is mediated by the inhibition of IkappaB kinase, nuclear factor-kappa B and STAT1, and depends on heme oxygenase-1 induction in mouse BV-2 microglia.
Journal: European journal of pharmacology 20051003
Title: Effects of the JNK inhibitor anthra[1,9-cd]pyrazol-6(2H)-one (SP-600125) on soluble guanylyl cyclase alpha1 gene regulation and cGMP synthesis.
Journal: American journal of physiology. Cell physiology 20051001
Title: Phosphorylation of the retinoid x receptor at the omega loop, modulates the expression of retinoic-acid-target genes with a promoter context specificity.
Journal: Cellular signalling 20051001
Title: Conditional expression of MAP kinase phosphatase-2 protects against genotoxic stress-induced apoptosis by binding and selective dephosphorylation of nuclear activated c-jun N-terminal kinase.
Journal: Cellular signalling 20051001
Title: Advanced glycosylation end products might promote atherosclerosis through inducing the immune maturation of dendritic cells.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20051001
Title: Mutually exclusive subsets of BH3-only proteins are activated by the p53 and c-Jun N-terminal kinase/c-Jun signaling pathways during cortical neuron apoptosis induced by arsenite.
Journal: Molecular and cellular biology 20051001
Title: JNK1-dependent antimitotic activity of thiazolidin compounds in human non-small-cell lung and colon cancer cells.
Journal: Cellular and molecular life sciences : CMLS 20051001
Title: Arsenic trioxide inhibits nuclear receptor function via SEK1/JNK-mediated RXRalpha phosphorylation.
Journal: The Journal of clinical investigation 20051001
Title: Mitomycin-C induces the apoptosis of human Tenon's capsule fibroblast by activation of c-Jun N-terminal kinase 1 and caspase-3 protease.
Journal: Investigative ophthalmology & visual science 20051001
Title: Shp2 is required for protein kinase C-dependent phosphorylation of serine 307 in insulin receptor substrate-1.
Journal: The Journal of biological chemistry 20050923
Title: c-Jun N-terminal kinase activation in dorsal root ganglion contributes to pain hypersensitivity.
Journal: Biochemical and biophysical research communications 20050916
Title: Calcium-activated RAF/MEK/ERK signaling pathway mediates p53-dependent apoptosis and is abrogated by alpha B-crystallin through inhibition of RAS activation.
Journal: Molecular biology of the cell 20050901
Title: Motorcycle exhaust particles induce IL-8 production through NF-kappaB activation in human airway epithelial cells.
Journal: Journal of toxicology and environmental health. Part A 20050901
Title: Blockage of NF-kappaB induces serine 15 phosphorylation of mutant p53 by JNK kinase in prostate cancer cells.
Journal: Cell cycle (Georgetown, Tex.) 20050901
Title: Ablation of the spindle assembly checkpoint by a compound targeting Mps1.
Journal: EMBO reports 20050901
Title: Inhibition of inflammatory bone erosion by constitutively active STAT-6 through blockade of JNK and NF-kappaB activation.
Journal: Arthritis and rheumatism 20050901
Title: Interleukin-25-induced chemokines and interleukin-6 release from eosinophils is mediated by p38 mitogen-activated protein kinase, c-Jun N-terminal kinase, and nuclear factor-kappaB.
Journal: American journal of respiratory cell and molecular biology 20050801
Title: Syndecan-2 overexpression induces osteosarcoma cell apoptosis: Implication of syndecan-2 cytoplasmic domain and JNK signaling.
Journal: Bone 20050801
Title: HNE increases HO-1 through activation of the ERK pathway in pulmonary epithelial cells.
Journal: Free radical biology & medicine 20050801
Title: Multiple anti-apoptotic pathways stimulated by EGF in cytotrophoblasts.
Journal: Placenta 20050801
Title: Human immunodeficiency virus type 1 envelope glycoprotein 120 induces cyclooxygenase-2 expression in neuroblastoma cells through a nuclear factor-kappaB and activating protein-1 mediated mechanism.
Journal: Journal of neurochemistry 20050801
Title: Inhibition of c-Jun-N-terminal-kinase sensitizes tumor cells to CD95-induced apoptosis and induces G2/M cell cycle arrest.
Journal: Cancer research 20050801
Title: Mitogen-activated protein kinases (MAPKs) mediate SIN-1/ glucose deprivation-induced death in rat primary astrocytes.
Journal: Archives of pharmacal research 20050801
Title: Histamine induces tissue factor expression: implications for acute coronary syndromes.
Journal: Circulation 20050719
Title: Eosinophil migration induced by mast cell chymase is mediated by extracellular signal-regulated kinase pathway.
Journal: Biochemical and biophysical research communications 20050715
Title: Radical mediators and mitogen-activated protein kinase signaling in oxygen-dependent radiosensitivity of human tumor cell lines.
Journal: Free radical biology & medicine 20050715
Title: Identification of a novel synthetic thiazolidin compound capable of inducing c-Jun NH2-terminal kinase-dependent apoptosis in human colon cancer cells.
Journal: Cancer research 20050715
Title: Cinnamaldehyde-induced apoptosis in human PLC/PRF/5 cells through activation of the proapoptotic Bcl-2 family proteins and MAPK pathway.
Journal: Life sciences 20050708
Title: P-glycoprotein-independent apoptosis induction by a novel synthetic compound, MMPT [5-[(4-methylphenyl)methylene]-2-(phenylamino)-4(5H)-thiazolone].
Journal: The Journal of pharmacology and experimental therapeutics 20050701
Title: Investigating the neuroprotective mechanism of action of a CDK5 inhibitor by phosphoproteome analysis.
Journal: Journal of cellular biochemistry 20050701
Title: CD437, a synthetic retinoid, induces apoptosis in human respiratory epithelial cells via caspase-independent mitochondrial and caspase-8-dependent pathways both up-regulated by JNK signaling pathway.
Journal: Experimental cell research 20050701
Title: Polypeptide from Chlamys farreri inhibits murine thymocytes apoptosis and modulates UVB induced signaling pathway activation.
Journal: Life sciences 20050701
Title: Role of c-Jun N-terminal kinase in cerebral vasospasm after experimental subarachnoid hemorrhage.
Journal: Stroke 20050701
Title: Inflammatory responses of corneal epithelial cells to Pseudomonas aeruginosa infection.
Journal: Current eye research 20050701
Title: Galpha12/13-mediated production of reactive oxygen species is critical for angiotensin receptor-induced NFAT activation in cardiac fibroblasts.
Journal: The Journal of biological chemistry 20050617
Title: Substituting c-Jun N-terminal kinase-3 (JNK3) ATP-binding site amino acid residues with their p38 counterparts affects binding of JNK- and p38-selective inhibitors.
Journal: Archives of biochemistry and biophysics 20050615
Title: Hibiscus anthocyanins rich extract-induced apoptotic cell death in human promyelocytic leukemia cells.
Journal: Toxicology and applied pharmacology 20050615
Title: Inhibition of the PI3K pathway sensitizes fludarabine-induced apoptosis in human leukemic cells through an inactivation of MAPK-dependent pathway.
Journal: Biochemical and biophysical research communications 20050603
Title: c-Jun NH2-terminal kinase mediation of angiotensin II-induced proliferation of human mesangial cells.
Journal: American journal of physiology. Renal physiology 20050601
Title: Neuroprotection against focal ischemic brain injury by inhibition of c-Jun N-terminal kinase and attenuation of the mitochondrial apoptosis-signaling pathway.
Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20050601
Title: Short-term interleukin-1(beta) increases the release of secreted APP(alpha) via MEK1/2-dependent and JNK-dependent alpha-secretase cleavage in neuroglioma U251 cells.
Journal: Journal of neuroscience research 20050601
Title: DNA topoisomerase I is a cofactor for c-Jun in the regulation of epidermal growth factor receptor expression and cancer cell proliferation.
Journal: Molecular and cellular biology 20050601
Title: Regulation of vitamin D receptor expression via estrogen-induced activation of the ERK 1/2 signaling pathway in colon and breast cancer cells.
Journal: The Journal of endocrinology 20050601
Title: Inflammatory pathway analysis using a high content screening platform.
Journal: Assay and drug development technologies 20050601
Title: Activation of c-Jun N-terminal kinase is required for neurite outgrowth of dopaminergic neuronal cells.
Journal: Neuroreport 20050531
Title: 2-Methoxyestradiol-induced apoptosis in human leukemia cells proceeds through a reactive oxygen species and Akt-dependent process.
Journal: Oncogene 20050526
Title: Contribution of mitogen-activated protein kinases to NMDA-induced neurotoxicity in the rat retina.
Journal: Brain research 20050524
Title: Cyclin-dependent kinase inhibitors and JNK act as molecular switches, regulating the choice between growth arrest and apoptosis induced by galectin-8.
Journal: The Journal of biological chemistry 20050513
Title: Keratinocyte growth factor expression by fibroblasts in pulmonary fibrosis: poor response to interleukin-1beta.
Journal: American journal of respiratory cell and molecular biology 20050501
Title: Inhibition of c-Jun N-terminal kinase limits lipopolysaccharide-induced pulmonary neutrophil influx.
Journal: American journal of respiratory and critical care medicine 20050501
Title: Juzentaihoto, a Kampo medicine, enhances IL-12 production by modulating Toll-like receptor 4 signaling pathways in murine peritoneal exudate macrophages.
Journal: International immunopharmacology 20050501
Title: Pepsin-digested bovine lactoferrin induces apoptotic cell death with JNK/SAPK activation in oral cancer cells.
Journal: Journal of pharmacological sciences 20050501
Title: c-Jun NH2-terminal kinase-interacting protein-3 facilitates phosphorylation and controls localization of amyloid-beta precursor protein.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20050413
Title: Requirement for ERK activation in acetone extract identified from Bupleurum scorzonerifolium induced A549 tumor cell apoptosis and keratin 8 phosphorylation.
Journal: Life sciences 20050408
Title: Inhibition of tumor growth, angiogenesis, and tumor cell proliferation by a small molecule inhibitor of c-Jun N-terminal kinase.
Journal: The Journal of pharmacology and experimental therapeutics 20050401
Title: Leptin induces hypertrophy via p38 mitogen-activated protein kinase in rat vascular smooth muscle cells.
Journal: Biochemical and biophysical research communications 20050401
Title: Cigarette smoke extract induces endothelial cell injury via JNK pathway.
Journal: Biochemical and biophysical research communications 20050401
Title: Jun N-terminal kinase is essential for CD40-mediated IgE class switching in B cells.
Journal: The Journal of allergy and clinical immunology 20050401
Title: Retinoic acid and arsenic trioxide cooperate for apoptosis through phosphorylated RXR alpha.
Journal: Oncogene 20050331
Title: Activation of c-Jun NH2-terminal kinase (JNK) signaling pathway is essential for the stimulation of hepatitis C virus (HCV) non-structural protein 3 (NS3)-mediated cell growth.
Journal: Virology 20050315
Title: A small molecule-kinase interaction map for clinical kinase inhibitors.
Journal: Nature biotechnology 20050301
Title: Rapamycin and UCN-01 synergistically induce apoptosis in human leukemia cells through a process that is regulated by the Raf-1/MEK/ERK, Akt, and JNK signal transduction pathways.
Journal: Molecular cancer therapeutics 20050301
Title: SAPK/JNK plays a role in transforming growth factor-beta-induced VEGF synthesis in osteoblasts.
Journal: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20050301
Title: The neuroprotective action of SP600125, a new inhibitor of JNK, on transient brain ischemia/reperfusion-induced neuronal death in rat hippocampal CA1 via nuclear and non-nuclear pathways.
Journal: Brain research 20050221
Title: Beta-amyloid-induced neuronal apoptosis involves c-Jun N-terminal kinase-dependent downregulation of Bcl-w.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20050202
Title: Cypermethrin blocks a mitochondria-dependent apoptotic signal initiated by deficient N-linked glycosylation within the endoplasmic reticulum.
Journal: Cellular signalling 20050201
Title: Disruption of microtubules leads to glucocorticoid receptor degradation in HeLa cell line.
Journal: Cellular signalling 20050201
Title: Superoxide dismutase inhibits the expression of vascular cell adhesion molecule-1 and intracellular cell adhesion molecule-1 induced by tumor necrosis factor-alpha in human endothelial cells through the JNK/p38 pathways.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20050201
Title: c-Jun N-terminal kinase is involved in mercuric ions-mediated interleukin-4 secretion in mast cells.
Journal: International archives of allergy and immunology 20050201
Title: Pro- and anti-apoptotic roles of c-Jun N-terminal kinase (JNK) in ethanol and acetaldehyde exposed rat hepatocytes.
Journal: European journal of pharmacology 20050131
Title: Induction of apoptosis and cytokine production in the Jurkat human T cells by deoxynivalenol: role of mitogen-activated protein kinases and comparison to other 8-ketotrichothecenes.
Journal: Toxicology 20050115
Title: Implication of the MAPK pathways in the maturation of human dendritic cells induced by nickel and TNF-alpha.
Journal: Toxicology 20050115
Title: Negative regulation of adipogenesis from human mesenchymal stem cells by Jun N-terminal kinase.
Journal: Biochemical and biophysical research communications 20050114
Title: Potential role of c-Jun NH2-terminal kinase in allergic airway inflammation and remodelling: effects of SP600125.
Journal: European journal of pharmacology 20050104
Title: Synthesis of the Na-K-ATPase gamma-subunit is regulated at both the transcriptional and translational levels in IMCD3 cells.
Journal: American journal of physiology. Renal physiology 20050101
Title: Signaling via the angiotensin-converting enzyme enhances the expression of cyclooxygenase-2 in endothelial cells.
Journal: Hypertension (Dallas, Tex. : 1979) 20050101
Title: Secreted beta-amyloid precursor protein activates microglia via JNK and p38-MAPK.
Journal: Neurobiology of aging 20050101
Title: Inhibition of inhibitor of kappaB kinases stimulates hepatic stellate cell apoptosis and accelerated recovery from rat liver fibrosis.
Journal: Gastroenterology 20050101
Title: Interleukin-1beta-induced transdifferentiation of renal proximal tubular cells is mediated by activation of JNK and p38 MAPK.
Journal: Nephron. Experimental nephrology 20050101
Title: Differential involvement of p38 and JNK MAP kinases in HIV-1 Tat and gp120-induced apoptosis and neurite degeneration in striatal neurons.
Journal: Neuroscience 20050101
Title: Induction and regulation of matrix metalloproteinase-12 in human airway smooth muscle cells.
Journal: Respiratory research 20050101
Title: JNK2 translocates to the mitochondria and mediates cytochrome c release in PC12 cells in response to 6-hydroxydopamine.
Journal: The Journal of biological chemistry 20041231
Title: Pseudolaric acid B induces apoptosis via activation of c-Jun N-terminal kinase and caspase-3 in HeLa cells.
Journal: Experimental & molecular medicine 20041231
Title: Paraoxonase 2 (PON2) expression is upregulated via a reduced-nicotinamide-adenine-dinucleotide-phosphate (NADPH)-oxidase-dependent mechanism during monocytes differentiation into macrophages.
Journal: Free radical biology & medicine 20041215
Title: p38alpha, but not p38beta, inhibits the phosphorylation and presence of c-FLIPS in DISC to potentiate Fas-mediated caspase-8 activation and type I apoptotic signaling.
Journal: Journal of cell science 20041215
Title: c-Jun NH2-terminal kinase activation contributes to hypoxia-inducible factor 1alpha-dependent P-glycoprotein expression in hypoxia.
Journal: Cancer research 20041215
Title: Lipopolysaccharide stimulates nitric oxide synthase-2 expression in murine skeletal muscle and C(2)C(12) myoblasts via Toll-like receptor-4 and c-Jun NH(2)-terminal kinase pathways.
Journal: American journal of physiology. Cell physiology 20041201
Title: Role of c-Jun N-terminal kinase on lipopolysaccharide induced maturation of human monocyte-derived dendritic cells.
Journal: International immunology 20041201
Title: Methotrexate enhances prostaglandin D2-stimulated heat shock protein 27 induction in osteoblasts.
Journal: Prostaglandins, leukotrienes, and essential fatty acids 20041201
Title: Induction of serine racemase by inflammatory stimuli is dependent on AP-1.
Journal: Annals of the New York Academy of Sciences 20041201
Title: Microtubule disarray in primary cultures of human hepatocytes inhibits transcriptional activity of the glucocorticoid receptor via activation of c-jun N-terminal kinase.
Journal: Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia 20041201
Title: KR-31378 protects cardiac H9c2 cells from chemical hypoxia-induced cell death via inhibition of JNK/p38 MAPK activation.
Journal: The Japanese journal of physiology 20041201
Title: c-Jun phosphorylation by the human vaccinia-related kinase 1 (VRK1) and its cooperation with the N-terminal kinase of c-Jun (JNK).
Journal: Oncogene 20041125
Title: Identification of promoters bound by c-Jun/ATF2 during rapid large-scale gene activation following genotoxic stress.
Journal: Molecular cell 20041119
Title: UV-induced apoptosis in SH-SY5Y cells: contribution to apoptosis by JNK signaling and cytochrome c.
Journal: Journal of neuroscience research 20041115
Title: Rescuing melanoma epitope-specific cytolytic T lymphocytes from activation-induced cell death, by SP600125, an inhibitor of JNK: implications in cancer immunotherapy.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20041115
Title: Transactivation of epidermal growth factor receptor mediates catecholamine-induced growth of vascular smooth muscle.
Journal: Circulation research 20041112
Title: Role of mitogen-activated protein kinase activation in injured and intact primary afferent neurons for mechanical and heat hypersensitivity after spinal nerve ligation.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20041110
Title: Transforming growth factor-beta induces the expression of ANF and hypertrophic growth in cultured cardiomyoblast cells through ZAK.
Journal: Biochemical and biophysical research communications 20041105
Title: Altered processing of the amyloid precursor protein and decreased expression of ADAM 10 by chronic hypoxia in SH-SY5Y: no role for the stress-activated JNK and p38 signalling pathways.
Journal: Brain research. Molecular brain research 20041104
Title: Curcumin induces c-jun N-terminal kinase-dependent apoptosis in HCT116 human colon cancer cells.
Journal: Carcinogenesis 20041101
Title: Inhibition of c-Jun phosphorylation reduces axonal outgrowth of adult rat nodose ganglia and dorsal root ganglia sensory neurons.
Journal: Molecular and cellular neurosciences 20041101
Title: Possible pathophysiological roles of mitogen-activated protein kinases (MAPKs) in endometriosis.
Journal: American journal of reproductive immunology (New York, N.Y. : 1989) 20041101
Title: Protective effects of SP600125 a new inhibitor of c-jun N-terminal kinase (JNK) and extracellular-regulated kinase (ERK1/2) in an experimental model of cerulein-induced pancreatitis.
Journal: Life sciences 20041029
Title: Induction of thyroid cancer cell apoptosis by a novel nuclear factor kappaB inhibitor, dehydroxymethylepoxyquinomicin.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20041015
Title: Hypoxia-responsive growth factors upregulate periostin and osteopontin expression via distinct signaling pathways in rat pulmonary arterial smooth muscle cells.
Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20041001
Title: Cross-talk between phosphatidylinositol 3-kinase/AKT and c-jun NH2-terminal kinase mediates survival of isolated human islets.
Journal: Endocrinology 20041001
Title: Calcium-mediated activation of c-Jun NH2-terminal kinase (JNK) and apoptosis in response to cadmium in murine macrophages.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20041001
Title: MAP kinases differentially regulate the expression of macrophage hyperactivity after thermal injury.
Journal: Journal of cellular physiology 20041001
Title: Mechanical stimulation and mitogen-activated protein kinase signaling independently regulate osteogenic differentiation and mineralization by calcifying vascular cells.
Journal: Journal of biomechanics 20041001
Title: High sensitivity of fibroblast cell lines derived from LEC rats to heat treatment.
Journal: The Journal of veterinary medical science 20041001
Title: Anti-apoptotic and pro-apoptotic effect of NEPP11 on manganese-induced apoptosis and JNK pathway activation in PC12 cells.
Journal: Brain research 20040924
Title: Andrographolide acts through inhibition of ERK1/2 and Akt phosphorylation to suppress chemotactic migration.
Journal: European journal of pharmacology 20040913
Title: Regulation of tumor necrosis factor-alpha in glioma cells by lead and lipopolysaccharide: involvement of common signaling pathway.
Journal: Toxicology letters 20040910
Title: Indirubin-3'-oxime inhibits c-Jun NH2-terminal kinase: anti-apoptotic effect in cerebellar granule neurons.
Journal: Neuroscience letters 20040909
Title: The c-Jun N-terminal protein kinase signaling pathway mediates Bax activation and subsequent neuronal apoptosis through interaction with Bim after transient focal cerebral ischemia.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20040908
Title: Simvastatin induces heme oxygenase-1: a novel mechanism of vessel protection.
Journal: Circulation 20040907
Title: Inhibition of human immunodeficiency virus type 1 replication by Z-100, an immunomodulator extracted from human-type tubercle bacilli, in macrophages.
Journal: The Journal of general virology 20040901
Title: Flavonoids inhibit tumor necrosis factor-alpha-induced up-regulation of intercellular adhesion molecule-1 (ICAM-1) in respiratory epithelial cells through activator protein-1 and nuclear factor-kappaB: structure-activity relationships.
Journal: Molecular pharmacology 20040901
Title: Glucose-potentiated chemotaxis in human vascular smooth muscle is dependent on cross-talk between the PI3K and MAPK signaling pathways.
Journal: Circulation research 20040820
Title: Critical roles of c-Jun signaling in regulation of NFAT family and RANKL-regulated osteoclast differentiation.
Journal: The Journal of clinical investigation 20040816
Title: p21(Cip-1/SDI-1/WAF-1) expression via the mitogen-activated protein kinase signaling pathway in insulin-induced chondrogenic differentiation of ATDC5 cells.
Journal: Biochemical and biophysical research communications 20040806
Title: A c-Jun NH2-terminal kinase inhibitor SP600125 (anthra[1,9-cd]pyrazole-6 (2H)-one) blocks activation of pancreatic stellate cells.
Journal: The Journal of pharmacology and experimental therapeutics 20040801
Title: Jun N-terminal kinase promotes proliferation of immature erythroid cells and erythropoietin-dependent cell lines.
Journal: Blood 20040801
Title: JNK MAP kinase is involved in the humoral immune response of the greater wax moth larvae Galleria mellonella.
Journal: Archives of insect biochemistry and physiology 20040801
Title: Interleukin-4 increases murine airway response to kinins, via up-regulation of bradykinin B1-receptors and altered signalling along mitogen-activated protein kinase pathways.
Journal: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20040801
Title: The herbicide paraquat induces dopaminergic nigral apoptosis through sustained activation of the JNK pathway.
Journal: The Journal of biological chemistry 20040730
Title: Down-regulation of WW domain-containing oxidoreductase induces Tau phosphorylation in vitro. A potential role in Alzheimer's disease.
Journal: The Journal of biological chemistry 20040716
Title: Induction of matrix metalloproteinase-2 by tenascin-X deficiency is mediated through the c-Jun N-terminal kinase and protein tyrosine kinase phosphorylation pathway.
Journal: Experimental cell research 20040715
Title: Mood stabilizers inhibit glucocorticoid receptor function in LMCAT cells.
Journal: European journal of pharmacology 20040714
Title: JNK signaling involved in the effects of cyclic AMP on IL-1beta plus IFNgamma-induced inducible nitric oxide synthase expression in hepatocytes.
Journal: Cellular signalling 20040701
Title: Amphetamine activates connexin43 gene expression in cultured neonatal rat cardiomyocytes through JNK and AP-1 pathway.
Journal: Cardiovascular research 20040701
Title: Effect of an inhibitor of Jun N-terminal protein kinase, SP600125, in single allergen challenge in sensitized rats.
Journal: Immunology 20040701
Title: C-jun N-terminal kinase modulates 1,25-dihydroxyvitamin D3-induced cytochrome P450 3A4 gene expression.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20040701
Title: Macrophage-mediated renal injury is dependent on signaling via the JNK pathway.
Journal: Journal of the American Society of Nephrology : JASN 20040701
Title: Activation of protein kinase C betaII/epsilon-c-Jun NH2-terminal kinase pathway and inhibition of mitogen-activated protein/extracellular signal-regulated kinase 1/2 phosphorylation in antitumor invasive activity induced by the polymethoxy flavonoid, nobiletin.
Journal: Molecular cancer therapeutics 20040701
Title: Thioredoxin-2 inhibits mitochondria-located ASK1-mediated apoptosis in a JNK-independent manner.
Journal: Circulation research 20040611
Title: Signaling pathways involved in induction of GADD45 gene expression and apoptosis by troglitazone in human MCF-7 breast carcinoma cells.
Journal: Oncogene 20040603
Title: Structural basis for the selective inhibition of JNK1 by the scaffolding protein JIP1 and SP600125.
Journal: The EMBO journal 20040602
Title: BRG1/BRM and prohibitin are required for growth suppression by estrogen antagonists.
Journal: The EMBO journal 20040602
Title: Angiotensin II increases Pax-2 expression in fetal kidney cells via the AT2 receptor.
Journal: Journal of the American Society of Nephrology : JASN 20040601
Title: Involvement of SAPK/JNK in prostaglandin E(1)-induced VEGF synthesis in osteoblast-like cells.
Journal: Molecular and cellular endocrinology 20040531
Title: Arsenite sensitizes human melanomas to apoptosis via tumor necrosis factor alpha-mediated pathway.
Journal: The Journal of biological chemistry 20040521
Title: Involvement of stress-activated protein kinase (SAPK)/c-Jun N-terminal kinase (JNK) in prostaglandin F2alpha-induced heat shock protein 27 in osteoblasts.
Journal: Prostaglandins, leukotrienes, and essential fatty acids 20040501
Title: The hierarchical relationship between MAPK signaling and ROS generation in human leukemia cells undergoing apoptosis in response to the proteasome inhibitor Bortezomib.
Journal: Experimental cell research 20040501
Title: Anti-apoptotic effects of curcumin on photosensitized human epidermal carcinoma A431 cells.
Journal: Journal of cellular biochemistry 20040501
Title: Dimethylaminopurine inhibits metabolic effects of insulin in primary adipocytes.
Journal: The Journal of nutritional biochemistry 20040501
Title: Involvement of ROS and JNK1 in selenite-induced apoptosis in Chang liver cells.
Journal: Experimental & molecular medicine 20040430
Title: JNK regulates HIPK3 expression and promotes resistance to Fas-mediated apoptosis in DU 145 prostate carcinoma cells.
Journal: The Journal of biological chemistry 20040423
Title: Suppression of cadmium-induced JNK/p38 activation and HSP70 family gene expression by LL-Z1640-2 in NIH3T3 cells.
Journal: Toxicology and applied pharmacology 20040415
Title: Differential requirement for c-Jun NH2-terminal kinase in TNFalpha- and Fas-mediated apoptosis in hepatocytes.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20040401
Title: The role of c-Jun N-terminal kinase in the A beta-mediated impairment of LTP and regulation of synaptic transmission in the hippocampus.
Journal: Neuropharmacology 20040401
Title: MAPK signaling pathways modulate IL-1beta expression in human keratinocytes.
Journal: Archives of biochemistry and biophysics 20040401
Title: Inhibition of AP-1 transcription activator induces myc-dependent apoptosis in HL60 cells.
Journal: Journal of cellular biochemistry 20040401
Title: Src and Cas are essentially but differentially involved in angiotensin II-stimulated migration of vascular smooth muscle cells via extracellular signal-regulated kinase 1/2 and c-Jun NH2-terminal kinase activation.
Journal: Molecular pharmacology 20040401
Title: Block of long-term potentiation by naturally secreted and synthetic amyloid beta-peptide in hippocampal slices is mediated via activation of the kinases c-Jun N-terminal kinase, cyclin-dependent kinase 5, and p38 mitogen-activated protein kinase as well as metabotropic glutamate receptor type 5.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20040331
Title: Lipopolysaccharide-induced c-Jun NH2-terminal kinase activation in human neutrophils: role of phosphatidylinositol 3-Kinase and Syk-mediated pathways.
Journal: The Journal of biological chemistry 20040319
Title: Inhibition of cell proliferation and cell cycle progression by specific inhibition of basal JNK activity: evidence that mitotic Bcl-2 phosphorylation is JNK-independent.
Journal: The Journal of biological chemistry 20040319
Title: Targeting the JNK MAPK cascade for inhibition: basic science and therapeutic potential.
Journal: Biochimica et biophysica acta 20040311
Title: Increased myeloproliferation in glutathione S-transferase pi-deficient mice is associated with a deregulation of JNK and Janus kinase/STAT pathways.
Journal: The Journal of biological chemistry 20040305
Title: Reciprocal regulation of beta-adrenergic receptor mRNA stability by mitogen activated protein kinase activation and inhibition.
Journal: Molecular and cellular biochemistry 20040301
Title: Thombospondin-1 disrupts estrogen-induced endothelial cell proliferation and migration and its expression is suppressed by estradiol.
Journal: Molecular cancer research : MCR 20040301
Title: Ventilation-induced neutrophil infiltration depends on c-Jun N-terminal kinase.
Journal: American journal of respiratory and critical care medicine 20040215
Title: Bcl-2 enhances neurite extension via activation of c-Jun N-terminal kinase.
Journal: Biochemical and biophysical research communications 20040206
Title: Sphingomyelinase of Helicobacter pylori-induced cytotoxicity in AGS gastric epithelial cells via activation of JNK kinase.
Journal: Biochemical and biophysical research communications 20040206
Title: c-Jun is regulated by combination of enhanced expression and phosphorylation in acute-overloaded rat heart.
Journal: American journal of physiology. Heart and circulatory physiology 20040201
Title: DEP-induced fra-1 expression correlates with a distinct activation of AP-1-dependent gene transcription in the lung.
Journal: American journal of physiology. Lung cellular and molecular physiology 20040201
Title: SP600125, a new JNK inhibitor, protects dopaminergic neurons in the MPTP model of Parkinson's disease.
Journal: Neuroscience research 20040201
Title: Regulation of polyamine analogue cytotoxicity by c-Jun in human MDA-MB-435 cancer cells.
Journal: Molecular cancer research : MCR 20040201
Title: 12-O-tetradecanoylphorbol-13-acetate may both potentiate and decrease the generation of apoptosis by the antileukemic agent arsenic trioxide in human promonocytic cells. Regulation by extracellular signal-regulated protein kinases and glutathione.
Journal: The Journal of biological chemistry 20040130
Title: All-trans retinoic acid potentiates Taxotere-induced cell death mediated by Jun N-terminal kinase in breast cancer cells.
Journal: Oncogene 20040115
Title: Activation of ERK1/2, JNK and PKB by hydrogen peroxide in human SH-SY5Y neuroblastoma cells: role of ERK1/2 in H2O2-induced cell death.
Journal: European journal of pharmacology 20040112
Title: An apoptotic signaling pathway in the interferon antiviral response mediated by RNase L and c-Jun NH2-terminal kinase.
Journal: The Journal of biological chemistry 20040109
Title: Production and release of neuroprotective tumor necrosis factor by P2X7 receptor-activated microglia.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20040107
Title: Bile acids up-regulate death receptor 5/TRAIL-receptor 2 expression via a c-Jun N-terminal kinase-dependent pathway involving Sp1.
Journal: The Journal of biological chemistry 20040102
Title: Opposed arsenite-induced signaling pathways promote cell proliferation or apoptosis in cultured lung cells.
Journal: Carcinogenesis 20040101
Title: Anthocyanidins inhibit activator protein 1 activity and cell transformation: structure-activity relationship and molecular mechanisms.
Journal: Carcinogenesis 20040101
Title: Retinoblastoma protein and CCAAT/enhancer-binding protein beta are required for 1,25-dihydroxyvitamin D3-induced monocytic differentiation of HL60 cells.
Journal: Cancer research 20040101
Title: Erianin induces a JNK/SAPK-dependent metabolic inhibition in human umbilical vein endothelial cells.
Journal: In vivo (Athens, Greece) 20040101
Title: Characterization of Cd-induced molecular events prior to cellular damage in primary rat hepatocytes in culture: activation of the stress activated signal protein JNK and transcription factor AP-1.
Journal: Journal of biochemical and molecular toxicology 20040101
Title: Inhibition of c-Jun NH2-terminal kinase or extracellular signal-regulated kinase improves lung injury.
Journal: Respiratory research 20040101
Title: p38 MAP kinase mediates bilirubin-induced neuronal death of cultured rat cerebellar granule neurons.
Journal: Neuroscience letters 20031226
Title: IGF-I stimulates IL-8 production in the promyelocytic cell line HL-60 through activation of extracellular signal-regulated protein kinase.
Journal: Cellular signalling 20031201
Title: Verotoxin activates mitogen-activated protein kinase in human peripheral blood monocytes: role in apoptosis and proinflammatory cytokine release.
Journal: British journal of pharmacology 20031201
Title: Allergen-induced inflammation and airway epithelial and smooth muscle cell proliferation: role of Jun N-terminal kinase.
Journal: British journal of pharmacology 20031201
Title: Transcriptional and posttranscriptional roles for p38 mitogen-activated protein kinase in upregulation of TNF-alpha expression by deoxynivalenol (vomitoxin).
Journal: Toxicology and applied pharmacology 20031201
Title: N-nitrosocarbofuran induces apoptosis in mouse brain microvascular endothelial cells (bEnd.3).
Journal: Journal of pharmacological sciences 20031201
Title: Biologic sequelae of c-Jun NH(2)-terminal kinase (JNK) activation in multiple myeloma cell lines.
Journal: Oncogene 20031127
Title: Inhibition of JNK signaling diminishes early but not late cellular stress-induced apoptosis.
Journal: International journal of cancer 20031120
Title: Inhibition by dexamethasone of interleukin 13 production via glucocorticoid receptor-mediated inhibition of c-Jun phosphorylation.
Journal: FEBS letters 20031120
Title: C-jun N-terminal kinase (JNK) inhibitor, SP600125, blocks interleukin (IL)-6-induced vascular endothelial growth factor (VEGF) production: cyclosporine A partially mimics this inhibitory effect.
Journal: Transplantation 20031115
Title: Effect of MG132, a proteasome inhibitor, on the expression of growth related oncogene protein-alpha in human umbilical vein endothelial cells.
Journal: Cytokine 20031107
Title: Lipopolysaccharide and proinflammatory cytokines stimulate interleukin-6 expression in C2C12 myoblasts: role of the Jun NH2-terminal kinase.
Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20031101
Title: The Jun N-terminal kinase inhibitor SP600125 is a ligand and antagonist of the aryl hydrocarbon receptor.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20031101
Title: Mitogen activated protein kinases selectively regulate palytoxin-stimulated gene expression in mouse keratinocytes.
Journal: Toxicology and applied pharmacology 20031101
Title: Activation of p38 mitogen-activated protein kinase and c-Jun-NH2-terminal kinase by BMP-2 and their implication in the stimulation of osteoblastic cell differentiation.
Journal: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20031101
Title: Disruption of the c-JUN-JNK complex by a cell-permeable peptide containing the c-JUN delta domain induces apoptosis and affects a distinct set of interleukin-1-induced inflammatory genes.
Journal: The Journal of biological chemistry 20031010
Title: Neuroprotective action of flavopiridol, a cyclin-dependent kinase inhibitor, in colchicine-induced apoptosis.
Journal: Neuropharmacology 20031001
Title: Involvement of the JNK-like protein of the Aedes albopictus mosquito cell line, C6/36, in phagocytosis, endocytosis and infection of West Nile virus.
Journal: Insect molecular biology 20031001
Title: Inhibition of the SAPK/JNK pathway blocks the stimulatory effects of glutamine on fluid secretion by the Malpighian tubules of Rhodnius prolixus.
Journal: Journal of insect physiology 20031001
Title: The cytoplasmic domain of Alzheimer's amyloid-beta protein precursor causes sustained apoptosis signal-regulating kinase 1/c-Jun NH2-terminal kinase-mediated neurotoxic signal via dimerization.
Journal: The Journal of pharmacology and experimental therapeutics 20030901
Title: Involvement of stress-activated protein kinase/c-Jun N-terminal kinase in endothelin-1-induced heat shock protein 27 in osteoblasts.
Journal: European journal of endocrinology 20030901
Title: Sphingosine-1-phosphate-induced ERK activation protects human melanocytes from UVB-induced apoptosis.
Journal: Archives of pharmacal research 20030901
Title: The in vivo roles of STEF/Tiam1, Rac1 and JNK in cortical neuronal migration.
Journal: The EMBO journal 20030815
Title: SP600125, an inhibitor of c-jun N-terminal kinase, activates CREB by a p38 MAPK-mediated pathway.
Journal: Biochemical and biophysical research communications 20030808
Title: Stretch-induced IL-8 depends on c-Jun NH2-terminal and nuclear factor-kappaB-inducing kinases.
Journal: American journal of physiology. Lung cellular and molecular physiology 20030801
Title: The roles of JNK and apoptotic signaling pathways in PEITC-mediated responses in human HT-29 colon adenocarcinoma cells.
Journal: Carcinogenesis 20030801
Title: c-Jun NH2-terminal kinase inhibitor anthra(1,9-cd)pyrazol-6(2H)-one reduces inducible nitric-oxide synthase expression by destabilizing mRNA in activated macrophages.
Journal: Molecular pharmacology 20030801
Title: Induction of matrix metalloproteinases-14 and -2 by cyclical mechanical stretch is mediated by tumor necrosis factor-alpha in cultured human umbilical vein endothelial cells.
Journal: Cardiovascular research 20030801
Title: Protection of rat hepatocytes from apoptosis by inhibition of c-Jun N-terminal kinase.
Journal: Surgery 20030801
Title: The structure of JNK3 in complex with small molecule inhibitors: structural basis for potency and selectivity.
Journal: Chemistry & biology 20030801
Title: c-Jun N-terminal kinase negatively regulates lipopolysaccharide-induced IL-12 production in human macrophages: role of mitogen-activated protein kinase in glutathione redox regulation of IL-12 production.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20030715
Title: c-Jun N-terminal kinase contributes to apoptotic synergy induced by tumor necrosis factor-related apoptosis-inducing ligand plus DNA damage in chemoresistant, p53 inactive mesothelioma cells.
Journal: The Journal of biological chemistry 20030711
Title: JNK phosphorylates paxillin and regulates cell migration.
Journal: Nature 20030710
Title: Ephrin-B1 reverse signaling activates JNK through a novel mechanism that is independent of tyrosine phosphorylation.
Journal: The Journal of biological chemistry 20030704
Title: Effects of transforming growth factor-[beta] and budesonide on mitogen-activated protein kinase activation and apoptosis in airway epithelial cells.
Journal: American journal of respiratory cell and molecular biology 20030701
Title: Definition of a novel growth factor-dependent signal cascade for the suppression of bile acid biosynthesis.
Journal: Genes & development 20030701
Title: The role of JNK and p38 MAPK activities in UVA-induced signaling pathways leading to AP-1 activation and c-Fos expression.
Journal: Neoplasia (New York, N.Y.) 20030701
Title: JNK-independent activation of c-Jun during neuronal apoptosis induced by multiple DNA-damaging agents.
Journal: The Journal of biological chemistry 20030620
Title: The activation of c-Jun NH2-terminal kinase (JNK) by DNA-damaging agents serves to promote drug resistance via activating transcription factor 2 (ATF2)-dependent enhanced DNA repair.
Journal: The Journal of biological chemistry 20030606
Title: C-Jun-NH2-terminal kinase mediates expression of connective tissue growth factor induced by transforming growth factor-beta1 in human lung fibroblasts.
Journal: American journal of respiratory cell and molecular biology 20030601
Title: Mechanisms for sensitization to TNF-induced apoptosis by acute glutathione depletion in murine hepatocytes.
Journal: Hepatology (Baltimore, Md.) 20030601
Title: Transcriptional regulation of heme oxygenase-1 gene expression by MAP kinases of the JNK and p38 pathways in primary cultures of rat hepatocytes.
Journal: The Journal of biological chemistry 20030516
Title: JNK-dependent release of mitochondrial protein, Smac, during apoptosis in multiple myeloma (MM) cells.
Journal: The Journal of biological chemistry 20030516
Title: Amyloid peptide-induced cytokine and chemokine expression in THP-1 monocytes is blocked by small inhibitory RNA duplexes for early growth response-1 messenger RNA.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20030515
Title: Comparison between ischaemic and anisomycin-induced preconditioning: role of p38 MAPK.
Journal: Cardiovascular drugs and therapy 20030501
Title: The specificities of protein kinase inhibitors: an update.
Journal: The Biochemical journal 20030401
Title: c-Jun-N-terminal kinase drives cyclin D1 expression and proliferation during liver regeneration.
Journal: Hepatology (Baltimore, Md.) 20030401
Title: Rapid and selective apoptosis in human leukemic cells induced by Aplidine through a Fas/CD95- and mitochondrial-mediated mechanism.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20030401
Title: Involvement of SAPK/JNK in basic fibroblast growth factor-induced vascular endothelial growth factor release in osteoblasts.
Journal: The Journal of endocrinology 20030401
Title: Immediate-early gene induction by the stresses anisomycin and arsenite in human osteosarcoma cells involves MAPK cascade signaling to Elk-1, CREB and SRF.
Journal: Oncogene 20030327
Title: Modulation of insulin-stimulated degradation of human insulin receptor substrate-1 by Serine 312 phosphorylation.
Journal: The Journal of biological chemistry 20030307
Title: Grape seed extract inhibits EGF-induced and constitutively active mitogenic signaling but activates JNK in human prostate carcinoma DU145 cells: possible role in antiproliferation and apoptosis.
Journal: Oncogene 20030306
Title: Type 2 deiodinase expression is stimulated by growth factors in human vascular smooth muscle cells.
Journal: Molecular and cellular endocrinology 20030227
Title: Molecular mechanisms mediating antimyeloma activity of proteasome inhibitor PS-341.
Journal: Blood 20030215
Title: Critical role of c-Jun N-terminal protein kinase activation in troglitazone-induced apoptosis of human HepG2 hepatoma cells.
Journal: Molecular pharmacology 20030201
Title: Involvement of c-Jun N-terminal kinase in amyloid precursor protein-mediated neuronal cell death.
Journal: Journal of neurochemistry 20030201
Title: Inhibition of hippocampal Jun N-terminal kinase enhances short-term memory but blocks long-term memory formation and retrieval of an inhibitory avoidance task.
Journal: The European journal of neuroscience 20030201
Title: Salicylic acid reverses phorbol 12-myristate-13-acetate (PMA)- and tumor necrosis factor alpha (TNFalpha)-induced insulin receptor substrate 1 (IRS1) serine 307 phosphorylation and insulin resistance in human embryonic kidney 293 (HEK293) cells.
Journal: The Journal of biological chemistry 20030103
Title: A role for c-Jun N-terminal kinase in the inhibition of long-term potentiation by interleukin-1beta and long-term depression in the rat dentate gyrus in vitro.
Journal: Neuroscience 20030101
Title: p8 inhibits the growth of human pancreatic cancer cells and its expression is induced through pathways involved in growth inhibition and repressed by factors promoting cell growth.
Journal: Molecular cancer 20030101
Title: Up-regulation of c-jun mRNA in cardiac myocytes requires the extracellular signal-regulated kinase cascade, but c-Jun N-terminal kinases are required for efficient up-regulation of c-Jun protein.
Journal: The Biochemical journal 20021115
Title: [Synergetic effect of mitogen-activated protein kinase pathway on expression of tumor necrosis factor alpha gene in RAW 264.7 cells induced by lipopolysaccharide].
Journal: Zhonghua yi xue za zhi 20021025
Title: c-Jun N-terminal kinase activation mediates downregulation of connexin43 in cardiomyocytes.
Journal: Circulation research 20021004
Title: Activation of the mitochondrial caspase cascade in the absence of protein synthesis does not require c-Jun N-terminal kinase.
Journal: Archives of biochemistry and biophysics 20020915
Title: An inhibitor of c-jun aminoterminal kinase (SP600125) represses c-Jun activation, DNA-binding and PMA-inducible 92-kDa type IV collagenase expression.
Journal: Biochimica et biophysica acta 20020508
Title: Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.
Journal: The Journal of biological chemistry 20020419
Title: Stress-activated protein kinase/c-Jun N-terminal kinase (JNK) plays a part in endothelin-1-induced vascular endothelial growth factor synthesis in osteoblasts.
Journal: Journal of cellular biochemistry 20020101
Title: Coadministration of UCN-01 with MEK1/2 inhibitors potently induces apoptosis in BCR/ABL+ leukemia cells sensitive and resistant to ST1571.
Journal: Cancer biology & therapy 20020101
Title: Role of JNK in hypertonic activation of Cl(-)-dependent Na(+)/H(+) exchange in Xenopus oocytes.
Journal: American journal of physiology. Cell physiology 20011201
Title: SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase.
Journal: Proceedings of the National Academy of Sciences of the United States of America 20011120
Title: TAK1/JNK and p38 have opposite effects on rat hepatic stellate cells.
Journal: Hepatology (Baltimore, Md.) 20011101
Title: c-Jun N-terminal kinase is required for metalloproteinase expression and joint destruction in inflammatory arthritis.
Journal: The Journal of clinical investigation 20010701
Title: Mixed lineage kinase-3/JNK1 axis promotes migration of human gastric cancer cells following gastrin stimulation.
Journal: Molecular endocrinology (Baltimore, Md.)
Title: Bennett BL, et al. SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase. Proc Natl Acad Sci U S A, 2001, 98(24), 13681-13686.
Title: Vaishnav D, et al. SP600125, an inhibitor of c-jun N-terminal kinase, activates CREB by a p38 MAPK-mediated pathway. Biochem Biophys Res Commun, 2003, 307(4), 855-860.
Title: Kim JA, et al. SP600125 suppresses Cdk1 and induces endoreplication directly from G2 phase, independent of JNK inhibition. Oncogene, 2010, 29(11), 1702-1716.
Title: Zheng Y, et al. JNK inhibitor SP600125 protects against lipopolysaccharide-induced acute lung injury via upregulation ofclaudin-4. Exp Ther Med. 2014 Jul;8(1):153-158.
Title: Zhang H, et al. SP600125 Suppresses Keap1 Expression and Results in NRF2-mediated Prevention of Diabetic Nephropathy. J Mol Endocrinol. J Mol Endocrinol. 2018 Feb;60(2):145-157.
Title: Yatsushige H, et al. Role of c-Jun N-terminal kinase in cerebral vasospasm after experimental subarachnoid hemorrhage. Stroke. 2005 Jul;36(7):1538-43.
