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129029-23-8,MFCD00866668
Catalog No.:AA000YQ1

129029-23-8 | Ocaperidone

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
97%
in stock  
$36.00   $25.00
- +
5mg
97%
in stock  
$90.00   $63.00
- +
10mg
97%
in stock  
$134.00   $94.00
- +
25mg
>98.0%(HPLC)
in stock  
$175.00   $123.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA000YQ1
Chemical Name:
Ocaperidone
CAS Number:
129029-23-8
Molecular Formula:
C24H25FN4O2
Molecular Weight:
420.4793
MDL Number:
MFCD00866668
SMILES:
Fc1ccc2c(c1)onc2C1CCN(CC1)CCc1c(C)nc2n(c1=O)cccc2C
Properties
Computed Properties
 
Complexity:
856  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
31  
Hydrogen Bond Acceptor Count:
6  
Rotatable Bond Count:
4  
XLogP3:
3.3  

Literature

Title: Efficacy of antipsychotic agents at human 5-HT(1A) receptors determined by [3H]WAY100,635 binding affinity ratios: relationship to efficacy for G-protein activation.

Journal: European journal of pharmacology 20011005

Title: Agonistic properties of alniditan, sumatriptan and dihydroergotamine on human 5-HT1B and 5-HT1D receptors expressed in various mammalian cell lines.

Journal: British journal of pharmacology 19980401

Title: 5-HT1A receptor activates Na+/H+ exchange in CHO-K1 cells through Gialpha2 and Gialpha3.

Journal: The Journal of biological chemistry 19970321

Title: Alniditan, a new 5-hydroxytryptamine1D agonist and migraine-abortive agent: ligand-binding properties of human 5-hydroxytryptamine1D alpha, human 5-hydroxytryptamine1D beta, and calf 5-hydroxytryptamine1D receptors investigated with [3H]5-hydroxytryptamine and [3H]alniditan.

Journal: Molecular pharmacology 19961201

Title: Leysen JE, et al. In vitro and in vivo receptor binding and effects on monoamine turnover in rat brain regions of the novel antipsychotics risperidone and ocaperidone. Mol Pharmacol. 1992 Mar;41(3):494-508.

Title: Cosi C, et al. Agonist, antagonist, and inverse agonist properties of antipsychotics at human recombinant 5-HT(1A) receptors expressed in HeLa cells. Eur J Pharmacol. 2001 Dec 14;433(1):55-62.

Title: Rijnders HJ, et al. The discriminative stimulus properties of buspirone involve dopamine-2 receptor antagonist activity. Psychopharmacology (Berl). 1993;111(1):55-61.

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