Title: Hyper-O-GlcNAcylation inhibits the induction of heat shock protein 70 (Hsp 70) by sodium arsenite in HeLa cells.
Journal: Biological & pharmaceutical bulletin 20140101
Title: Computational analysis of human OGA structure in complex with PUGNAc and NAG-thiazoline derivatives.
Journal: Journal of chemical information and modeling 20121022
Title: Evidence of the involvement of O-GlcNAc-modified human RNA polymerase II CTD in transcription in vitro and in vivo.
Journal: The Journal of biological chemistry 20120706
Title: Beta-hexosaminidase activity of the oral pathogen Tannerella forsythia influences biofilm formation on glycoprotein substrates.
Journal: FEMS immunology and medical microbiology 20120601
Title: Glucosamine modulates TNF-α-induced ICAM-1 expression and function through O-linked and N-linked glycosylation in human retinal pigment epithelial cells.
Journal: Investigative ophthalmology & visual science 20120424
Title: PUGNAc treatment leads to an unusual accumulation of free oligosaccharides in CHO cells.
Journal: Journal of biochemistry 20120401
Title: Identification of a specific inhibitor of nOGA - a caspase-3 cleaved O-GlcNAcase variant during apoptosis.
Journal: Biochemistry. Biokhimiia 20120201
Title: Modulators of sensitivity and resistance to inhibition of PI3K identified in a pharmacogenomic screen of the NCI-60 human tumor cell line collection.
Journal: PloS one 20120101
Title: Active-pocket size differentiating insectile from bacterial chitinolytic β-N-acetyl-D-hexosaminidases.
Journal: The Biochemical journal 20110915
Title: Down-regulation of β-N-acetyl-D-glucosaminidase increases Akt1 activity in thyroid anaplastic cancer cells.
Journal: Oncology reports 20110901
Title: O-GlcNAcylation increases non-amyloidogenic processing of the amyloid-β precursor protein (APP).
Journal: Biochemical and biophysical research communications 20110121
Title: O-GlcNAc modification of NFκB p65 inhibits TNF-α-induced inflammatory mediator expression in rat aortic smooth muscle cells.
Journal: PloS one 20110101
Title: The role of O-linked GlcNAc modification on the glucose response of ChREBP.
Journal: Biochemical and biophysical research communications 20101126
Title: Inhibition of phospholamban phosphorylation by O-GlcNAcylation: implications for diabetic cardiomyopathy.
Journal: Glycobiology 20101001
Title: Inhibition of O-GlcNAcase using a potent and cell-permeable inhibitor does not induce insulin resistance in 3T3-L1 adipocytes.
Journal: Chemistry & biology 20100924
Title: Quantification of O-glycosylation stoichiometry and dynamics using resolvable mass tags.
Journal: Nature chemical biology 20100901
Title: Cytoskeletal keratin glycosylation protects epithelial tissue from injury.
Journal: Nature cell biology 20100901
Title: Stressing the role of O-GlcNAc: linking cell survival to keratin modification.
Journal: Nature cell biology 20100901
Title: O-GlcNAc modification of proteins affects volume regulation in Jurkat cells.
Journal: European biophysics journal : EBJ 20100701
Title: An improved route to PUGNAc and its galacto-configured congener.
Journal: The Journal of organic chemistry 20100604
Title: Quantum mechanical/molecular mechanical molecular dynamics simulation of wild-type and seven mutants of CpNagJ in complex with PUGNAc.
Journal: The journal of physical chemistry. B 20100527
Title: Development of GlcNAc-inspired iminocyclitiols as potent and selective N-acetyl-beta-hexosaminidase inhibitors.
Journal: ACS chemical biology 20100521
Title: Glycopeptide-specific monoclonal antibodies suggest new roles for O-GlcNAc.
Journal: Nature chemical biology 20100501
Title: Increasing O-GlcNAc levels: An overview of small-molecule inhibitors of O-GlcNAcase.
Journal: Biochimica et biophysica acta 20100201
Title: O-linked beta-N-acetylglucosaminylation in mouse embryonic neural precursor cells.
Journal: Journal of neuroscience research 20091201
Title: O-GlcNAc signaling attenuates ER stress-induced cardiomyocyte death.
Journal: American journal of physiology. Heart and circulatory physiology 20091101
Title: Excessive O-GlcNAcylation of proteins suppresses spontaneous cardiogenesis in ES cells.
Journal: FEBS letters 20090806
Title: Insight into a strategy for attenuating AmpC-mediated beta-lactam resistance: structural basis for selective inhibition of the glycoside hydrolase NagZ.
Journal: Protein science : a publication of the Protein Society 20090701
Title: O-GLcNAc post-translational modifications regulate the entry of neurons into an axon branching program.
Journal: Developmental neurobiology 20090201
Title: Unique hexosaminidase reduces metabolic survival signal and sensitizes cardiac myocytes to hypoxia/reoxygenation injury.
Journal: Circulation research 20090102
Title: O-linked beta-N-acetylglucosamine: a new piece of the cardioprotection puzzle?
Journal: Circulation research 20090102
Title: Elevation of global O-GlcNAc levels in 3T3-L1 adipocytes by selective inhibition of O-GlcNAcase does not induce insulin resistance.
Journal: The Journal of biological chemistry 20081212
Title: A quantum mechanics/molecular mechanics study of the protein-ligand interaction of two potent inhibitors of human O-GlcNAcase: PUGNAc and NAG-thiazoline.
Journal: The journal of physical chemistry. B 20081113
Title: The synthesis and biological evaluation of some carbocyclic analogues of PUGNAc.
Journal: Carbohydrate research 20081103
Title: Increased protein O-GlcNAc modification inhibits inflammatory and neointimal responses to acute endoluminal arterial injury.
Journal: American journal of physiology. Heart and circulatory physiology 20080701
Title: O-glycosylation of FoxO1 increases its transcriptional activity towards the glucose 6-phosphatase gene.
Journal: FEBS letters 20080305
Title: Proteomic analysis of O-GlcNAc modifications derived from streptozotocin and glucosamine induced beta-cell apoptosis.
Journal: Journal of biochemistry and molecular biology 20071130
Title: O-GlcNAc modification modulates the expression of osteocalcin via OSE2 and Runx2.
Journal: Biochemical and biophysical research communications 20071019
Title: Increased O-GlcNAc levels during reperfusion lead to improved functional recovery and reduced calpain proteolysis.
Journal: American journal of physiology. Heart and circulatory physiology 20070901
Title: The sweet nature of cardioprotection.
Journal: American journal of physiology. Heart and circulatory physiology 20070901
Title: Small molecule inhibitors of a glycoside hydrolase attenuate inducible AmpC-mediated beta-lactam resistance.
Journal: The Journal of biological chemistry 20070720
Title: Glucosamine-induced increase in Akt phosphorylation corresponds to increased endoplasmic reticulum stress in astroglial cells.
Journal: Molecular and cellular biochemistry 20070401
Title: The protective effects of PUGNAc on cardiac function after trauma-hemorrhage are mediated via increased protein O-GlcNAc levels.
Journal: Shock (Augusta, Ga.) 20070401
Title: Analysis of PUGNAc and NAG-thiazoline as transition state analogues for human O-GlcNAcase: mechanistic and structural insights into inhibitor selectivity and transition state poise.
Journal: Journal of the American Chemical Society 20070124
Title: Inhibition of O-GlcNAcase by a gluco-configured nagstatin and a PUGNAc-imidazole hybrid inhibitor.
Journal: Chemical communications (Cambridge, England) 20061113
Title: Akt1 is dynamically modified with O-GlcNAc following treatments with PUGNAc and insulin-like growth factor-1.
Journal: FEBS letters 20060529
Title: Structural insights into the mechanism and inhibition of eukaryotic O-GlcNAc hydrolysis.
Journal: The EMBO journal 20060405
Title: An O-GlcNAcase-specific inhibitor and substrate engineered by the extension of the N-acetyl moiety.
Journal: Journal of the American Chemical Society 20060405
Title: A divergent synthesis of 2-acyl derivatives of PUGNAc yields selective inhibitors of O-GlcNAcase.
Journal: Organic & biomolecular chemistry 20060307
Title: Inhibition of O-GlcNAcase by PUGNAc is dependent upon the oxime stereochemistry.
Journal: Bioorganic & medicinal chemistry 20060201
Title: O-GlcNAc modification on IRS-1 and Akt2 by PUGNAc inhibits their phosphorylation and induces insulin resistance in rat primary adipocytes.
Journal: Experimental & molecular medicine 20050630
Title: Protein O-GlcNAc modulates motility-associated signaling intermediates in neutrophils.
Journal: The Journal of biological chemistry 20050415
Title: Selective decrease of membrane-associated PKC-alpha and PKC-epsilon in response to elevated intracellular O-GlcNAc levels in transformed human glial cells.
Journal: Biochimica et biophysica acta 20050415
Title: Relationship between protein O-linked glycosylation and insulin-stimulated glucose transport in rat skeletal muscle following calorie restriction or exposure to O-(2-acetamido-2-deoxy-d-glucopyranosylidene)amino-N-phenylcarbamate.
Journal: Acta physiologica Scandinavica 20050301
Title: Prolonged incubation in PUGNAc results in increased protein O-Linked glycosylation and insulin resistance in rat skeletal muscle.
Journal: Diabetes 20040401
Title: Cytosolic O-GlcNAc accumulation is not involved in beta-cell death in HIT-T15 or Min6.
Journal: Biochemical and biophysical research communications 20010921
Title: O-GlcNAc expression in developing and ageing mouse brain.
Journal: Biochimie 20010701
